LOCUS       DAVHSL010000001        81548 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000001 DAVHSL010000000
VERSION     DAVHSL010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 81548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81548
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.001"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..272)
                     /locus_tag="VVR39_000001"
     CDS             complement(<1..272)
                     /locus_tag="VVR39_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029571.1"
                     /translation="MSNIEQQLAELRQSTLDRLKEIHHEGEKELQDLRVSVLGKKGSL
                     TDLLKPQLFTPNLKTIQNPCLSLDPGWFLFSPNGCFLLDKKEFPLYG"
     gene            complement(566..2290)
                     /locus_tag="VVR39_000002"
     CDS             complement(566..2290)
                     /locus_tag="VVR39_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HEU6029572.1"
                     /translation="MPRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFF
                     FGGDAFSGNNLSNQELINRYHIGGARYMNGSPEQVQGLINDLQSYSKVPLLVAANCDS
                     GGDGAVKGGTYISSGAQSEASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWR
                     NTIVNTRAYGTNADDVIAYTSAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNE
                     LSPEEWDDSFGRVYHHHIEAGVEMVMAGHIALLYYQQKLNPSLKDEDILPATLAPELI
                     QDLLKEKLEFNGLVITDASHMLGMTAAMRREDYVPAAIAAGCDMFLFFNNLEEDFEFM
                     LNGYRNGVITKERLHDALRRILGLKAKLNLHVKQAEGTLLKSADELAIIGCEEHLAWQ
                     REAADKAITLLKDTQHNLPISPETHRRIRLYYLEGEKEGIMAASTEVVDNLKSALEAR
                     GYEVTVNDGTTRIKGKTLQYREEVDLALTVANVIGYGAQNNYRIQWKTAMSNEVPWYV
                     HEVSTIFVSLNYTTHLHDVTMVKTAINAYHHNKNTIESLLDKLEGKDEFYGIPNENVW
                     ANKWQAKL"
     gene            complement(2301..4091)
                     /locus_tag="VVR39_000003"
     CDS             complement(2301..4091)
                     /locus_tag="VVR39_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEU6029573.1"
                     /translation="MTHLVDLRKKPYNLDEEAISWVENTIAQMTLDEKIGHLFVNMGI
                     QRTEKYLTGVLEDYKIAAVRYNPGPAADIWEQNYILQTKSKIPLLIAANTESGGNGAV
                     TDGTKIGDEIKIAATADSRHAYEMGKVAGIEAAAVGCNASFAPIMDLSRNWRNPIIAN
                     RTWGADVDQVIELSKEYMRGIMEHGIVPFAKHFPGDGIDERDHHLSFASNPMTKSEWM
                     ETFGRIYGEMADAGLPGIMAGHIHLPNVEKEMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMIGMTASMPRRELLPTAIEAGCDLFLFFNDPEEDLQWMKEGLKNG
                     LLTEERLHDALRRTLGLKAKLGLHLFEGRRQEIMLPKEEALALIGKDEAKNLAKEVAD
                     KAITLVKSKQEGIFPVNPDRYKRILLVEVDGYKGGFGAMINAGKKRAADTLKELLEAR
                     GHEVSIWENTEARIAKLPEEERPAAIANVYASKRPIAEITDNYDLIINLVDVNSGGTT
                     QRIIWPAAKGTPDQPFYVHEIPTIVVSVQHPFALADMPQVATYINAYDGLPVTLETLV
                     TKLAGESSFTGVSPVDAYCGLVDTHIWRGN"
     gene            complement(4138..4935)
                     /locus_tag="VVR39_000004"
     CDS             complement(4138..4935)
                     /locus_tag="VVR39_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6029574.1"
                     /translation="MKTDYVFCVDSDGCAMDTMTYKHKLFFGPLAADVFGVQDREAFL
                     TEWNRVNLYSRTRGINRFVGLVKGLEFAGVTGIEQLKNWVATTDSLSNASLEKLIAEQ
                     PSKDLELALEWSKQVNQAIKNYTGPVLAFIGVHKGLEKLSQLGKVYVVSSANKEAVDE
                     EWSEQGLLDFVTELYCQDRGKKEDVIKLLIDKGYNPDNIIMIGDSPGDLKAAELNNVH
                     FYPILVGREMRSWADLTETIADDFVNQTFAGEKETNLIQAFWKNLDD"
     gene            complement(4938..5777)
                     /locus_tag="VVR39_000005"
     CDS             complement(4938..5777)
                     /locus_tag="VVR39_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6029575.1"
                     /translation="MTRVIEFKDKVVVITGAGGVLCGYLAKEFAKAGAKVALLDLNEV
                     AAQVFVDEIESVGGVAKTYKSNVLSKENLEEVRQQVLADFGPVDILVNGAGGNNPKAT
                     TDNEFHEIGLPVDTKTFFDLDEAGINFVFNLNYLGTLLPTQVFAQDMIGRSGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFFLTNQNRGLLF
                     DESGQPTARANKILTNTPMGRFGEAEELVGGVFFLADENLASFVNGVVLPIDGGFSAY
                     SGV"
     gene            complement(5780..6880)
                     /locus_tag="VVR39_000006"
     CDS             complement(5780..6880)
                     /locus_tag="VVR39_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEU6029576.1"
                     /translation="MKMSFRWYGKKDPVTLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKQMVEEAGLEITVIESIPVHEDIKQGKPNRDELIENYKTSIRNVGAAGIPVVC
                     YNFMPVFDWTRSDLHHPLPDGSTSLAFLKSDLAGVDPVADDLNLPGWDSSYSKEEMKN
                     VIENYRQNISEEDLWANLEYFIKAIMPTAEEAGVKMAIHPDDPPYGIFGLPRIITGQE
                     AVERFLNLYDSEHNGITMCVGSYASDPKNDVLAMTEYALKRNRINFMHTRNVTAGAWG
                     FQETAHLSQSGDIDMNGVVKLLVDYDWQGALRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKTPDFGIKVKTVGNKEG"
     gene            complement(6894..8294)
                     /gene="uxaC"
                     /locus_tag="VVR39_000007"
     CDS             complement(6894..8294)
                     /gene="uxaC"
                     /locus_tag="VVR39_000007"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEU6029577.1"
                     /translation="MSFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKV
                     YEDIVDLWLGGDHYKWRLMRANGISEEEITGFASKLDKFKAWARTLERAFGNPLYHWS
                     HLELRQVFGIEELLTEENAERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDN
                     LEWHKRLAEDSPIDTVVAPTFRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEAL
                     GQRVSYFAQHGCRASDISFTAITYEEATLEELNDILLARMVGKEVGQSGINKWQTAIF
                     RELCRMYKKHGFVTQVHFGALRNNHTGLFEKLGADVGVDSIGDQTCLTGNLNRLLDNL
                     VKENALPKMIWYNLNPGYNIALANTLANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQ
                     MNAYAEQGMLANFVGMLTDSRSFLSYQRHDYFRRILATYVGQWIVDEEVPEDYDRLGQ
                     FVEAISYYNAKEFFEQ"
     gene            complement(8296..8916)
                     /gene="eda"
                     /locus_tag="VVR39_000008"
     CDS             complement(8296..8916)
                     /gene="eda"
                     /locus_tag="VVR39_000008"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6029578.1"
                     /translation="MLRQLKENYFFAVIRGKDEQDAKEIARHAVLGGIRNIEITFSTP
                     NAATVIKELQEEFSDDSSVVIGAGTVMNLNLAQEAIGAGASFLVSPHFDKKIQELAQE
                     TGVLYFPGCATATEIVTASQAGCSIIKLFPGGVLGHGFIKDIHGPVPEVDLMPSGGVS
                     VDNVADWKKAGACAVGIGSALASRVQAEGYDSVTLIARSFVAALEG"
     gene            complement(9039..9755)
                     /locus_tag="VVR39_000009"
     CDS             complement(9039..9755)
                     /locus_tag="VVR39_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEU6029579.1"
                     /translation="MAKPLVEKASERLLELILERGYEVGDKLPNEYELAQDLEVGRST
                     VREAVRSLATRNILEVRQGSGTYISSKKGVSEDPLGFSLVRDRVKLTTDLFEVRYLLE
                     PRIAERVAQFASDEDVAKLEEIVLAIEEAVAAGDTKHLELDVKFHCMLAEMSGNLAMT
                     SLMPVINQSIHLINENYSNRQMKSNSLQAHRNILMAIKQRHPVAAYDSMLAHIISVRQ
                     VVLSEWFDKDMTLHGLNDHK"
     gene            complement(9801..11600)
                     /gene="uidA"
                     /locus_tag="VVR39_000010"
     CDS             complement(9801..11600)
                     /gene="uidA"
                     /locus_tag="VVR39_000010"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEU6029580.1"
                     /translation="MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSF
                     NDIVVDKEKRRFVGDNWYELMVAIPAVSDDEELVVRFGSVTHQAMVYADGQLIGKHKG
                     GFTPFECLVPSELYGLDQFRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFD
                     FFNYAGIQRNVHLYKRPKNRVDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFN
                     QEGQELGLLENGRIVIDNPRLWEVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVE
                     NGQFFINGKPFYFKGFGKHEDTFINGRGFNEAANLMDLNLLKDIGANSFRTSHYPYSE
                     EMMRLADRLGIVVIDEVPAVGLFQLFNAALNLTGDSDEVKNTWEVMQTKDAHELVIDE
                     LIARDKNHPSVVMWVVANEPAGHEKGARAYFEPLIQRMRDRDPSNRPVTLVNIMTATP
                     DKDEVMDLVDVVCLNRYYGWYAAHGDLKMAEKGLRKELETWQELYPDKPILITEYGAD
                     TLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSISNVVGEQVWNFADFETTVGLIRIQGN
                     HKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK"
     gene            complement(11615..12643)
                     /locus_tag="VVR39_000011"
     CDS             complement(11615..12643)
                     /locus_tag="VVR39_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6029581.1"
                     /translation="MKKILAFGEVLLRLSPPHYQTLTQARSLECQFGGSELNVLASLA
                     QLGHSVELVTALPRNEVGKMAEHFLFARQIGQKYLIRKEGRLGLYYYQKGFSLRPSQV
                     TYDRDYSAFSLSREEDYDLEGIFEDVDWFHVSGITVALNPVIRQLAFRLMEMAKEQGI
                     KVSFDLNYRESLWSSFEEAREKLSPFVGLADICFGLEPIQLLNESGKDMKDELGLKRS
                     YENREILLSVVKALAETYSLQSIAFTQREMTYNNEYLLKAYLYQDGVLYETEKESIQV
                     LDRVGTGDAFTAGIILGYLQEKSPQEVVDLGMASFQFKHTIEGDVNVISQSDIDLLLK
                     KGSREIKR"
     gene            complement(12719..14272)
                     /locus_tag="VVR39_000012"
     CDS             complement(12719..14272)
                     /locus_tag="VVR39_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6029582.1"
                     /translation="MEKHVEQRVEDVTYNKAKLWQIILFAMNNSSTNIYLVAFTFVTY
                     LSTGVLGLAALFVSQLMGYIRIFDGFIDPTIGVIIDKTDTKFGKYRPILVLGNIITAS
                     SLFMMLGLSGVSENLRLPLFILVLIIHKIGYSLQQTITKAGQVALTNDPKQRPIFNIV
                     DGIATTVLMTGSQVVVSGTLVPKHGGFTPSFFQELFLGVVIISAILGILAIIGIWEKD
                     NKKYFGLGEKTQETKLKDYWKVIKGNKPLQVLSISAAFVKFVAQLFGDSVIGVMLYGI
                     IFGDYALSGKMSMLLILPGILVTVGAAQLARRKGLRFAYITALQLGIAGLVALAAMLF
                     SAKPGMLDLTNWNLYTIGFFVVYIIARYASGAPSGLVLTMGADITDYETSVSGRYLSG
                     MIGTIFSLTDSIASSFAPMVVGFVLAGIGFGKEYPTVETAFSTDLRMALIVLLTVIPA
                     AVLSVSLFLMKFYKLDREEMARIQEKIHVMKAAKDEERVRAIAKNVPLSDMDYVDVTQ
                     YKVEQYEDK"
     gene            complement(14459..14743)
                     /locus_tag="VVR39_000013"
                     /pseudo
     CDS             complement(14459..14743)
                     /locus_tag="VVR39_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735752.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease"
     gene            complement(14849..15394)
                     /locus_tag="VVR39_000014"
                     /pseudo
     CDS             complement(14849..15394)
                     /locus_tag="VVR39_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735752.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
     gene            complement(15424..15615)
                     /locus_tag="VVR39_000015"
     CDS             complement(15424..15615)
                     /locus_tag="VVR39_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6029583.1"
                     /translation="MDKENLSYVGKNLLLVVIVLLIAALVFVLGLVLGYGVIGDGDNV
                     FAVLSPAKWQELIGKFTGK"
     gene            complement(15658..16887)
                     /locus_tag="VVR39_000016"
     CDS             complement(15658..16887)
                     /locus_tag="VVR39_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU6029584.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAENDLMEAYSFSQFITYISAIGGQAFGVW
                     LLGLSVNNFSLVAGINACFFLVSAVILFLGKSKLSLSMSSADGEKLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFFDNS"
     gene            complement(17078..17929)
                     /gene="rgg"
                     /locus_tag="VVR39_000017"
     CDS             complement(17078..17929)
                     /gene="rgg"
                     /locus_tag="VVR39_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU6029585.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SFPFLSVSLFTRYVREMVHKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKGNETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            18053..18394
                     /locus_tag="VVR39_000018"
     CDS             18053..18394
                     /locus_tag="VVR39_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6029586.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            18452..18532
                     /locus_tag="VVR39_000019"
                     /pseudo
     CDS             18452..18532
                     /locus_tag="VVR39_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(18693..20396)
                     /gene="ilvD"
                     /locus_tag="VVR39_000020"
     CDS             complement(18693..20396)
                     /gene="ilvD"
                     /locus_tag="VVR39_000020"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU6029587.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(20629..21561)
                     /locus_tag="VVR39_000021"
     CDS             complement(20629..21561)
                     /locus_tag="VVR39_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU6029588.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(21558..22415)
                     /locus_tag="VVR39_000022"
     CDS             complement(21558..22415)
                     /locus_tag="VVR39_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6029589.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNKNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(22419..23765)
                     /locus_tag="VVR39_000023"
     CDS             complement(22419..23765)
                     /locus_tag="VVR39_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6029590.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(23778..24062)
                     /locus_tag="VVR39_000024"
     CDS             complement(23778..24062)
                     /locus_tag="VVR39_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6029591.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(24066..26096)
                     /locus_tag="VVR39_000025"
     CDS             complement(24066..26096)
                     /locus_tag="VVR39_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU6029592.1"
                     /translation="MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            26288..27295
                     /locus_tag="VVR39_000026"
     CDS             26288..27295
                     /locus_tag="VVR39_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6029593.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            27298..27498
                     /locus_tag="VVR39_000027"
     CDS             27298..27498
                     /locus_tag="VVR39_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6029594.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            27650..27832
                     /gene="rpmF"
                     /locus_tag="VVR39_000028"
     CDS             27650..27832
                     /gene="rpmF"
                     /locus_tag="VVR39_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU6029595.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            27848..27997
                     /gene="rpmG"
                     /locus_tag="VVR39_000029"
     CDS             27848..27997
                     /gene="rpmG"
                     /locus_tag="VVR39_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6029596.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(28477..30282)
                     /locus_tag="VVR39_000030"
     CDS             complement(28477..30282)
                     /locus_tag="VVR39_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEU6029597.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKD
                     KGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWF
                     TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            30617..30799
                     /locus_tag="VVR39_000031"
     CDS             30617..30799
                     /locus_tag="VVR39_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6029598.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            30744..31549
                     /locus_tag="VVR39_000032"
                     /pseudo
     CDS             30744..31549
                     /locus_tag="VVR39_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(32186..34066)
                     /locus_tag="VVR39_000033"
     CDS             complement(32186..34066)
                     /locus_tag="VVR39_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6029599.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGSETAQFSILSSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTVNQWHTIATASTIY
                     TT"
     gene            complement(34060..34929)
                     /locus_tag="VVR39_000034"
     CDS             complement(34060..34929)
                     /locus_tag="VVR39_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6029600.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(35013..37658)
                     /locus_tag="VVR39_000035"
     CDS             complement(35013..37658)
                     /locus_tag="VVR39_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU6029601.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(37749..39029)
                     /locus_tag="VVR39_000036"
     CDS             complement(37749..39029)
                     /locus_tag="VVR39_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU6029602.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            39200..41284
                     /locus_tag="VVR39_000037"
     CDS             39200..41284
                     /locus_tag="VVR39_000037"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU6029603.1"
                     /translation="MKPLLETIDTRLGTTNRHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSTCKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFEITGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(41324..43003)
                     /locus_tag="VVR39_000038"
     CDS             complement(41324..43003)
                     /locus_tag="VVR39_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6029604.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSLLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFVTYRNELYKEDLALGAEVS
                     GPTLSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            43759..44988
                     /gene="arcA"
                     /locus_tag="VVR39_000039"
     CDS             43759..44988
                     /gene="arcA"
                     /locus_tag="VVR39_000039"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU6029605.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            45046..46062
                     /gene="argF"
                     /locus_tag="VVR39_000040"
     CDS             45046..46062
                     /gene="argF"
                     /locus_tag="VVR39_000040"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU6029606.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            46227..47174
                     /gene="arcC"
                     /locus_tag="VVR39_000041"
     CDS             46227..47174
                     /gene="arcC"
                     /locus_tag="VVR39_000041"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU6029607.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVIKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            47385..48896
                     /locus_tag="VVR39_000042"
     CDS             47385..48896
                     /locus_tag="VVR39_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU6029608.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            48918..50249
                     /locus_tag="VVR39_000043"
     CDS             48918..50249
                     /locus_tag="VVR39_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU6029609.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLYGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            50343..50470
                     /locus_tag="VVR39_000044"
                     /pseudo
     CDS             50343..50470
                     /locus_tag="VVR39_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(50653..50943)
                     /locus_tag="VVR39_000045"
     CDS             complement(50653..50943)
                     /locus_tag="VVR39_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029610.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(50931..51182)
                     /locus_tag="VVR39_000046"
     CDS             complement(50931..51182)
                     /locus_tag="VVR39_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6029611.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            51386..51463
                     /locus_tag="VVR39_000047"
                     /pseudo
     CDS             51386..51463
                     /locus_tag="VVR39_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(51626..52510)
                     /locus_tag="VVR39_000048"
     CDS             complement(51626..52510)
                     /locus_tag="VVR39_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6029612.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(52655..53806)
                     /locus_tag="VVR39_000049"
     CDS             complement(52655..53806)
                     /locus_tag="VVR39_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU6029613.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(53952..55718)
                     /locus_tag="VVR39_000050"
     CDS             complement(53952..55718)
                     /locus_tag="VVR39_000050"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU6029614.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(55731..56459)
                     /locus_tag="VVR39_000051"
     CDS             complement(55731..56459)
                     /locus_tag="VVR39_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU6029615.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            complement(56474..59485)
                     /locus_tag="VVR39_000052"
     CDS             complement(56474..59485)
                     /locus_tag="VVR39_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEU6029616.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKGKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDNKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDKIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGDEV
                     VFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPFTP
                     GNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSANH
                     LNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSYSG
                     KHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQGK
                     YTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVNPK
                     TGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWAND
                     IENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFMFK
                     NTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQGDR
                     QWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVIAH
                     PAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGVLK
                     TDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFVYN
                     YKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSNAQ
                     DANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTNNS
                     YDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            complement(59496..61712)
                     /locus_tag="VVR39_000053"
     CDS             complement(59496..61712)
                     /locus_tag="VVR39_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6029617.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            complement(61734..63605)
                     /locus_tag="VVR39_000054"
     CDS             complement(61734..63605)
                     /locus_tag="VVR39_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEU6029618.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIKNVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            complement(63611..64930)
                     /locus_tag="VVR39_000055"
     CDS             complement(63611..64930)
                     /locus_tag="VVR39_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6029619.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            complement(64927..65766)
                     /locus_tag="VVR39_000056"
     CDS             complement(64927..65766)
                     /locus_tag="VVR39_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6029620.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            complement(65769..66698)
                     /locus_tag="VVR39_000057"
     CDS             complement(65769..66698)
                     /locus_tag="VVR39_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6029621.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            complement(66786..68078)
                     /locus_tag="VVR39_000058"
     CDS             complement(66786..68078)
                     /locus_tag="VVR39_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6029622.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLAAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWDDFTQAMASIRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVHTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            complement(68108..69511)
                     /locus_tag="VVR39_000059"
     CDS             complement(68108..69511)
                     /locus_tag="VVR39_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU6029623.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLLSQGKINEDTELK
                     DIMTNIADTKYYYPQLS"
     gene            69687..70460
                     /locus_tag="VVR39_000060"
     CDS             69687..70460
                     /locus_tag="VVR39_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6029624.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(71588..73093)
                     /gene="adcA"
                     /locus_tag="VVR39_000061"
     CDS             complement(71588..73093)
                     /gene="adcA"
                     /locus_tag="VVR39_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU6029625.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(73103..73909)
                     /locus_tag="VVR39_000062"
     CDS             complement(73103..73909)
                     /locus_tag="VVR39_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6029626.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(73902..74606)
                     /locus_tag="VVR39_000063"
     CDS             complement(73902..74606)
                     /locus_tag="VVR39_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6029627.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(74606..75046)
                     /gene="adcR"
                     /locus_tag="VVR39_000064"
     CDS             complement(74606..75046)
                     /gene="adcR"
                     /locus_tag="VVR39_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU6029628.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(75201..76469)
                     /gene="dltD"
                     /locus_tag="VVR39_000065"
     CDS             complement(75201..76469)
                     /gene="dltD"
                     /locus_tag="VVR39_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU6029629.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(76462..76701)
                     /gene="dltC"
                     /locus_tag="VVR39_000066"
     CDS             complement(76462..76701)
                     /gene="dltC"
                     /locus_tag="VVR39_000066"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU6029630.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(76715..77959)
                     /gene="dltB"
                     /locus_tag="VVR39_000067"
     CDS             complement(76715..77959)
                     /gene="dltB"
                     /locus_tag="VVR39_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU6029631.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(77956..79506)
                     /gene="dltA"
                     /locus_tag="VVR39_000068"
     CDS             complement(77956..79506)
                     /gene="dltA"
                     /locus_tag="VVR39_000068"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU6029632.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GQPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMIPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(79527..79658)
                     /locus_tag="VVR39_000069"
     CDS             complement(79527..79658)
                     /locus_tag="VVR39_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU6029633.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(79982..81160)
                     /locus_tag="VVR39_000070"
     CDS             complement(79982..81160)
                     /locus_tag="VVR39_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6029634.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
BASE COUNT        24868 a        17692 c        14254 g        24734 t
ORIGIN      
        1 ccataaaggg gaaactcttt tttgtctagt aaaaaacacc cattgggtga aaaaagaaac
       61 catccaggat ctaagctaag gcaaggattc tggatggttt ttagatttgg ggtgaataat
      121 tggggtttta ataagtctgt caacgagcct tttttcccca agacagagac acgtaggtct
      181 tgcaattctt tctcaccttc atggtgaatt tcttttagtc tatcaagcgt gctttgacgc
      241 aactcagcca actgttgttc aatgtttgac ataattcctc caataaaaaa aacgcatgac
      301 accattcgta tcggagcgtt gtcacgcggc accatccgtt ttcatctgct aggcagacct
      361 ttattctaag tccttatatg agtgaattcg accaactttc actgattgag ctttcagtca
      421 cggctcaact ccctggacag tttccatagg tgtactagtc tcacaaactt ctattcaatt
      481 aagaatattc tatcaaaatg caggtcattt ggcaagaaat cttgctaaaa aactccttct
      541 atctacgata gaaaggagct tacatttata gtttcgcttg ccacttattg gcccaaacat
      601 tttcatttgg aataccatag aactcatctt taccttccaa tttatcaagg agggattcaa
      661 tggtattttt gttgtggtga taggcgttga tagctgtttt caccatggta acatcgtgaa
      721 gatgggtagt gtaattgaga gaaacaaaga tggttgatac ttcatgaaca taccaaggaa
      781 cttcattgga catggctgtt ttccattgga tacggtaatt attctgcgca ccgtatccga
      841 tgacattggc aaccgtcaat gctaaatcta cttcttctcg atattgtaga gtttttcctt
      901 taatccgagt agtaccatca ttgacagtca cttcatagcc acgcgcttcc aaggcggatt
      961 tgagattatc tactacttct gtacttgccg ccataatccc ctctttttcc ccttctaagt
     1021 aatataagcg gatccttcga tgagtttcag ggctgattgg aagattgtgt tgggtatctt
     1081 tcaaaagagt aatcgcctta tctgccgcct cacgttgcca agccaaatgt tcttcacatc
     1141 caataattgc caactcatca gcggatttca acagagtccc ttctgcttgt ttgacatgaa
     1201 gattgagttt ggctttcaat cctaaaatgc ggcgaagagc atcatgaaga cgttctttgg
     1261 taatcacgcc atttctgtaa ccgttcagca taaactcaaa atcttcttcc aggttattga
     1321 aaaacaagaa catatcacaa cccgctgcaa tggcagctgg tacatagtct tcgcgacgca
     1381 tagccgctgt catccccagc atgtgactgg catcggtaat aaccaagcca ttgaattcca
     1441 gtttttcttt caataaatct tgaatcaatt cgggagctag tgttgctggt aagatatcct
     1501 catcctttaa actagggttc aatttttgtt gataatatag caaggcgata tgaccagcca
     1561 taaccatctc tacaccagct tcaatatggt ggtgatagac acgaccaaaa ctatcgtccc
     1621 actcttctgg tgatagctca ttgacaccga gaactaggtg ctgatctcgc tcttctgtcc
     1681 catcacctgg aaaatgtttt atgcattgaa taacatctct ttcggcagtc aaaccctcta
     1741 aataggcgct ggtataagca ataacatcgt cagcattggt cccataagct ctggtattca
     1801 caatggtatt gcgccagttt tgaacgatgt ctacgcatgg gtcaaaattg acattgacac
     1861 ccaatgcagt ttcctccctc gcagatacaa gacctgcaag atatggaatg cgagaatcac
     1921 gactggcttc agactgggca cctgaagaaa tgtaagttcc acctttcaca gctccatctc
     1981 caccggaatc acagttagct gcaacaagga gaggaacttt tgaatatgac tgtaagtcat
     2041 tgataagccc ctgtacttgc tcaggactac cattcatata acgagcaccg ccaatgtggt
     2101 atcgattaat cagctcctga ttgctcagat tattcccgct aaaggcatca ccgccaaaga
     2161 agaagaggtt gacaaaaagt tggccaattt tttcttcatc tgtcagattt tcaagggtac
     2221 tctctaccca gacaatctga tcatcattca agtaatatgg tttctttctt aaatcaacta
     2281 gtctaggcat tgctgtctcc ttaattccca cgccaaatat gtgtatctac caagccacag
     2341 taagcatcaa caggggacac tcctgtaaac gatgattctc ctgctagttt ggtaactaag
     2401 gtttccaaag ttactggtaa accatcatag gcattgatat aggttgctac ttgtggcata
     2461 tctgccagag caaagggatg ctgaacagaa acaacgatgg ttggtatttc atgaacatag
     2521 aacggctgat ctggtgttcc cttggcagca ggccaaataa ttcgttgagt tgttccacct
     2581 gaattgacat caaccaaatt gataatcaaa tcatagttat ctgtgatttc tgcaatagga
     2641 cgcttagatg catagacatt agcaatcgca gctggtcttt cttcttctgg taatttggca
     2701 atccttgctt ctgtattttc ccagatagac acttcgtgac ctcgtgcttc taacaattct
     2761 tttagcgtat cagccgccct cttctttcct gcattaatca tggcaccaaa gccacctttg
     2821 tagccgtcga cttcaaccaa taaaatccgt ttatagcgat ctggattgac tgggaaaatg
     2881 ccttcttgct tggattttac caaggtaata gccttgtcag ctacttcttt tgcaagattt
     2941 ttagcctcat cttttccaat taaagccagc gcttcttctt ttggcaacat aatttcctga
     3001 cgacgacctt caaaaaggtg gaggccgagt ttagctttca agcccaaggt ccgacgaaga
     3061 gcatcatgga gccgctcctc agtgagaagt ccatttttca acccctcttt catccattgc
     3121 aaatcttctt caggatcatt gaaaaagagg aagagatcgc agcccgcttc aatagctgtc
     3181 ggtaagagct cacgacgtgg catagatgct gtcataccaa tcatgtgact agcatccgtc
     3241 acaattgcgc cgttgtagcc taactcccca cgcaacaatt catccaagag ggttttattc
     3301 aacgaagctg gcaacatatc atccaattca cgttctggat gcatttcttt ctcaacattt
     3361 ggcaaatgaa tgtgccccgc catgatacct ggaagacctg catcagccat ttcaccgtaa
     3421 atccgtccaa aggtttccat ccattcagat tttgtcattg gattagaagc aaaagagagg
     3481 tggtgatcgc gttcatcaat accatcgcca ggaaaatgct tcgcaaaagg cacaatgcca
     3541 tgttccataa tcccacgcat gtattcttta gacagttcaa tcacttggtc aacatctgct
     3601 ccccaagtac gattggcgat aattggattt cgccagttgc ggctaagatc cataatcggt
     3661 gcaaaggaag cgttacagcc tactgctgct gcttcaatcc ctgcaacttt ccccatctca
     3721 taagcatggc gagaatcagc tgttgctgca attttgattt catcgccaat ttttgttcca
     3781 tctgtaacag caccatttcc accagattct gtgtttgctg ctattaagag aggaattttg
     3841 gacttagttt gcaaaatata gttttgttcc caaatatctg ccgctggccc tggattatac
     3901 cgaacagcag caatcttgta atcttccaat actcctgtca gatatttctc cgtccgctgg
     3961 atacccatgt tgacaaagag atgtcctatt ttttcatcca atgtcatctg agcaatcgta
     4021 ttttcaaccc atgaaatagc ttcttcatca aggttataag gtttcttccg taagtctacc
     4081 aaatgtgtca tcgttgcctc caaaaaagct agagggcatg tagcctctag cccttatcta
     4141 gtcgtctaaa tttttccaaa atgcttgtat caagtttgtt tctttctcac ctgcaaatgt
     4201 ttgattaaca aagtcatctg caatcgtttc tgttaaatct gcccaagatc gcatctcccg
     4261 tcctactaaa ataggataga agtggacatt attcagttct gcagccttca aatcaccagg
     4321 agaatcacca atcattatga tgttatcagg gttataaccc ttatcaatca ataactttat
     4381 cacatcctcc ttcttgcctc gatcttgaca ataaagttca gtaacaaaat ccagtaatcc
     4441 ttgctcggac cactcttcgt cgaccgcttc tttattggct gaagaaacga catatacttt
     4501 tcccaactgg ctcaattttt ccaagccttt gtgaacgccg atgaatgcta aaacaggacc
     4561 agtatagttc ttaatagctt gattgacttg tttggaccat tctaaagcta attctaaatc
     4621 tttcgatggt tgctccgcta tcagcttttc cagagaagca tttgacaaag aatctgtggt
     4681 cgcaacccaa tttttcaact gttcaatacc agtcacacct gcaaattcta aacctttaac
     4741 caacccgaca aaacggttaa tgccacgtgt tcgtgaatag agattgactc gattccattc
     4801 cgttaagaaa gcctccctat cttgaactcc aaagacatct gctgccaagg ggccaaagaa
     4861 gagcttatgt ttgtaggtca tggtgtccat tgcacagcca tcagagtcca cacaaaatac
     4921 ataatctgtc ttcatgatta gactcctgaa taggctgaaa atccaccgtc aatcggtaaa
     4981 acaacgccat ttacaaaact tgccagattc tcatctgcta agaagaagac acctccaact
     5041 agctcttctg cttcgccaaa ccgtcccatc ggtgtattgg tcaaaatctt gttggcacgt
     5101 gctgtcggtt gacctgactc atcaaataac aagccgcggt tctgattggt taaaaagaaa
     5161 cctggtgcaa tggcattgca acggattcca acttttgaaa aatgcactgc taaccactga
     5221 gtaaaattgc tgatggcagc tttggcccct gaatatgctg gaattttagt caatggtgtg
     5281 aaggcgttca tgctagaaat attaataata tttgctccgc tacggccaat catatcctgc
     5341 gcaaatacct gagttggcaa gagagtacct aaataattca aattgaatac aaagttgatt
     5401 cccgcctcgt ccaaatcaaa gaaagttttg gtgtccacag gaagtccaat ttcatgaaac
     5461 tcattgtccg tcgttgcttt cggattgttg cctccggcac cgttaaccaa gatatcaact
     5521 ggaccaaaat ctgctaagac ttgttggcga acttcttcca aattttcctt agaaagaacg
     5581 ttagatttat aggtctttgc aactccacct actgactcaa tttcatcaac aaacacttga
     5641 gcagctacct catttaagtc caaaagagct actttagcac cagccttcgc aaattctttt
     5701 gccaaataac cacaaagaac gcctccagct ccggtaataa caacaacctt gtctttaaat
     5761 tcaataacac gtgtcataac tagccctcct tattcccaac tgtttttact ttaattccaa
     5821 aatctggtgt cttacctgcc gctcgcatat tcgcttcgta gagaccgtta aaataggtcg
     5881 caccgagtgc acggtcatac aaaccatagc caggtgtctt agtttggtct ccccagatac
     5941 gtcgaccatg gtctggtcgc aaagctcctt gccaatcata gtccaccaag agtttaacta
     6001 ctccattcat atcaatatcg ccagactgtg acaagtgtgc agtttcttgg aagccccaag
     6061 cccctgccgt cacattacga gtgtgcataa aattgatacg gttgcgtttg agagcatatt
     6121 ctgtcatggc gaggacatca tttttcggat cagaagcata ggaaccgaca cacatggtaa
     6181 ttccattatg ttctgagtca tagagattca aaaagcgttc aacagcttct tgaccagtaa
     6241 tgatacgtgg caatccaaaa attccatacg gaggatcatc tgggtgaatc gccattttca
     6301 ctcctgcttc ctcagccgtt ggcataatcg ccttgatgaa atactccaag tttgcccata
     6361 aatcttcctc agaaatattc tgacgataat tttcaataac gttcttcatt tcttccttgg
     6421 aataagatga atcccaaccc ggcaagttca agtcatctgc cacaggatca acaccagcta
     6481 aatcagattt cagaaaggct agggaagttg aaccatctgg aagaggatga tgcaagtccg
     6541 aacgtgtcca gtcaaataca ggcatgaagt tgtagcatac aactggaatt cctgccgctc
     6601 cgacattacg aatagatgtt ttatagtttt caatcagctc atcacggttt ggtttgcctt
     6661 gtttgatatc ttcatggaca ggaatggact caataactgt aatctctaaa cctgcctctt
     6721 ccaccatttg tttcaactca agaatatttt ccaaaggcca agcctgacct actggcacat
     6781 cgtagacagc tgtcacaatt ccctgcatgc caggaattgc tttaatctct tcaagtgtca
     6841 cagggtcttt ttttccatac catcgaaatg acattttcat gatttactct cctttattgt
     6901 tcaaaaaact ctttggcatt gtagtaagat attgcttcta caaactgacc taggcgatca
     6961 tagtcctcag gcacttcctc atccacaatc cattggccaa cataggtcgc caaaattcgt
     7021 ctgaaataat catggcgttg gtaggacaag aagctacgcg aatctgtcaa catccctaca
     7081 aaattagcaa gcataccttg ctcggcatag gcattcatct ggtcaatcat gcctagcttg
     7141 gtatcgttaa accaccaacc cgcaccaaac tgcaactgac tacgacgccc ttcctcattg
     7201 gcttggaaat ttgctaaggt gttggctagg gcaatattgt agcctggatt aaggttgtac
     7261 caaatcattt ttggaagggc attttccttg accaagttgt ccaacaaacg attcaagttc
     7321 cccgtcaagc acgtctggtc tccaatcgaa tctacaccta catctgctcc aagtttttca
     7381 aacagtcctg tatggttgtt tcgtaaggca ccaaaatgaa cttgtgtgac aaatccatgt
     7441 ttcttgtaca tacgacagag ttctctaaaa atagctgtct gccacttatt gatcccagat
     7501 tgtccgacct ctttccctac catcctagca agtaaaatat cattcagttc ttcaagtgta
     7561 gcttcttcat aggtaatagc tgtaaaacta atatcgcttg ctcggcaacc atgttgagca
     7621 aaataggaaa ctcgttggcc caaagcctct acaaaactgg caaagtctct tactgctacc
     7681 tccgtcactt cttccaagcg tttaataaat aaattgaaat ttctgtgttc tataaaggct
     7741 tcatctggac ggaaggttgg cgctactaca gtgtcaatgg gtgaatcttc tgccaaacgc
     7801 ttatgccatt ctaggttatc aagaggatgg tcagttgtcc cgataaaggc cactctggca
     7861 tcagcgatca gcttacgtgg actaatttga tgttcttgca aataggtatt gagctgatga
     7921 tagagacgct ctgcattttc ttccgtcagc aattcctcga taccaaaaac ttgtcgtaat
     7981 tccaaatgac tccaatggta gagaggattt ccaaaagcac gttccaaagt tcttgcccag
     8041 gctttaaatt tatctaactt acttgcaaat cctgtgatct cttcttctga aattccatta
     8101 gcccgcatca agcgccactt atagtgatct ccacctagcc acaaatcaac aatatcttca
     8161 tagaccttgt cttcaaaaat ttccttagga tccaagtgac aatgaaaatc atagataggt
     8221 agctctgcta ttttcacgta aagctcctta gcaggttcat tttttagcat aaagttttta
     8281 tcgttaaaac tcatcttatc cctccaaagc tgctacaaaa ctacgagcaa tcaacgttac
     8341 actgtcatag ccctcagcct gcacccgact cgccaatgcc gaaccaattc caacagcaca
     8401 agcaccggcc tttttccaat ccgcaacatt gtcaacagat actccaccag atggcatcaa
     8461 gtccacttca gggacgggac cgtgaatatc tttgataaac ccatgtccca atacaccacc
     8521 agggaaaagc ttgataatag aacacccagc ctgactagct gtaacaattt ccgttgcagt
     8581 tgcacaacca ggaaaataga gaacccctgt ctcttgcgct aactcttgga ttttcttatc
     8641 aaaatgagga ctaacaagaa aactagcccc tgcaccaatc gcctcctgtg cgagattaag
     8701 attcattact gtgcctgcac cgatgactac agacgaatca tctgagaact cttcttgtaa
     8761 ttctttgatg actgtcgcag cattaggcgt cgaaaatgta atctcgatat ttcgaatacc
     8821 acctaaaacc gcatgacgag caatttcttt tgcatcttgt tcatcttttc cgcgaatcac
     8881 tgcgaaaaag taattttctt ttaattgtct taacatctta acctccaatt agaaagcgtt
     8941 gctatttata gttatagtat ataattcatc agatgatttg tcaaggaaaa agcaaaaaaa
     9001 tacccagaag actcttctgg gcagttcgtt ttatatttct atttatgatc atttagacca
     9061 tgcaaggtca tgtctttatc gaaccattcg cttaaaacaa cctgtcttac cgatataata
     9121 tgcgctaaca tactatcata agctgcaaca gggtggcgtt gtttgattgc cattaagata
     9181 tttctgtgcg cctgtaaact atttgatttc atctgacgat ttgagtaatt ttcattgatc
     9241 agatgaatgg actgattaat gacaggcatc aggctagtca ttgccagatt cccactcatc
     9301 tcagccagca tacaatgaaa tttcacatcc aactccaaat gcttcgtgtc tccagcagct
     9361 acagcctctt caattgcaag gacaatttcc tctaatttag caacatcttc atccgaagca
     9421 aattgagcta cacgctccgc aattctcggt tcaagtaagt accgcacttc aaacaaatcc
     9481 gttgtcaact tcacacggtc tcttaccaaa gaaaaaccta gagggtcttc cgatactcct
     9541 tttttagagc tgatgtatgt ccctgaccct tggcgcacct ccagaatatt gcgagtagcc
     9601 aaactccgaa cagcttcacg aacagtcgaa cgtccaactt ctaaatcttg ggctaattca
     9661 tactcatttg gaagcttgtc tccaacctca tatcctcttt ccaaaatcaa ttccaataag
     9721 cgttctgatg ctttttctac caagggtttc gccatgtgct tggtcctcca atacaacttt
     9781 ctatttgcta ctattatagc ctatttcctt ttataatggt agtttggaat ggcagtccaa
     9841 cgtttcttta tttctctaac aatttgcttg ggttgacgat tccgtgagaa taaaccctta
     9901 tgatttcctt gaatccgaat gagaccaact gtggtttcaa aatcagcaaa attccagact
     9961 tgttcaccaa ccacatttga aatagaatca aaaaccctgt gattcatatc atagtaatcc
    10021 acttgaaatt cttccgtata aggaatatcc cacattgaat gcaagcctgg gagagtatct
    10081 gcaccatatt ctgtaatcaa aataggcttg tctggatata gttcttgcca tgtctctagt
    10141 tcctttcgaa gtcctttttc tgccatcttc aagtcgccat gagcagcata ccaaccataa
    10201 taacgattga gacagacaac atcaaccaag tccataactt catctttatc aggtgttgcc
    10261 gtcataatat taaccaaggt tacaggacgg ttagaaggat ctctatctct cattcgctga
    10321 atcagaggtt caaagtaagc acgtgcacct ttttcatgcc ctgccggttc attggctaca
    10381 acccacatca ctacggatgg atggttctta tcacgcgcta tcaattcatc aatcactagt
    10441 tcatgagcat ccttggtttg catgacttcc caggtatttt ttacctcatc agaatcccct
    10501 gtcaaattca aggctgcatt gaaaagctgg aacagcccga ctgctggcac ctcgtcaatg
    10561 actacaattc ccaatcgatc tgccagtcgc atcatttctt cagaatatgg ataatgggac
    10621 gttctaaatg aattagctcc aatatctttg agtaagttca aatccatcag attagctgct
    10681 tcgttgaagc cgcggccatt gataaaggtg tcttcatgtt taccaaatcc cttgaaatag
    10741 aacggttttc cgttgatgaa aaattgtcca ttctcaactg caacactacg aagaccaaac
    10801 tgttcgcagt aagtatctaa taagctctca ccatcaaata attcgacttt tgcagtatag
    10861 agataggcat ctaaaacttc ccaaaggcgg ggattatcaa tgactatccg tccattttca
    10921 agaagaccta gttcctgtcc ttcttgatta aaaatgtgaa tacgaataga atcatactgc
    10981 ccaactgtcg ccacctcaac atgaacaaca gcttgagtca attcattatt cagttcagtc
    11041 cgaataacaa tatcatcaac cctatttttc ggacgtttat agagatgaac attccgctga
    11101 ataccagcat agttgaaaaa gtcaaaattt tccttgaccg tcttcacaat ttgaccgttt
    11161 tcatctacct cttcactgta attccctact ggaagggttg tataattcag ctcattattg
    11221 gcacaaactg tcaggcggaa ttgatccaaa ccatataatt ccgacggaac caggcattca
    11281 aaaggggtaa agcccccctt atgcttcccg attaactgac catccgcata gaccatagcc
    11341 tgatgcgtca cggagccaaa gcgcaccact aattcttcat catcagacac agcagggata
    11401 gccaccatca gttcatacca attatctccg acaaaacggc gtttctcttt gtcaacaaca
    11461 atatcattga aggaacttgg tacaaccatt acctcatccg tatctaacaa agattgaaca
    11521 tcattgtttc cttgcttaaa ggcccatatt ccgtttaaag aataaactga gcgtgttttc
    11581 gtttgaattg gatacaacat atttttccta ctttctatcg ttttatttca cgagaccctt
    11641 ttttcaataa caaatcaata tctgattgac tgatgacatt gacatcccct tcaatggtat
    11701 gtttgaattg aaaactagcc attcctaagt ctactacttc ctgcggcgat ttttcctgta
    11761 aatagcccaa aataattcct gccgtaaagg catcacctgt cccaactcgg tctaaaactt
    11821 gaatggattc cttttctgtt tcgtatagaa caccatcttg atacaaataa gctttcagca
    11881 agtattcatt attgtaggtc atttctcgct gggtaaaagc aatgctttgc agagaatagg
    11941 tttctgctaa agctttaacg actgacaata ggatttctct attttcataa gatcgcttca
    12001 agcccagttc atccttcata tcttttccag attcatttag gagttggata ggctctagac
    12061 caaagcaaat atctgccaag cctacaaaag gagataactt ctccctagct tcctcaaaag
    12121 aagaccacaa actttcccga taattcaggt caaaggaaac cttaatacct tgctcctttg
    12181 ccatctccat caaacgaaag gccagttgac gaataactgg attcagggca actgtaatac
    12241 cactcacatg gaaccaatca acatcttcaa atatgccttc caaatcgtaa tcttcttccc
    12301 ttgataggct aaaagcagaa taatcacggt cgtaggtcac ctgactgggt ctaagagaaa
    12361 aacctttttg ataataataa agtcccagtc ttccctcttt tcgaatcaaa tatttctgtc
    12421 caatctgacg tgcaaagaga aaatgttctg ccattttgcc tacttcattc ctagggagtg
    12481 ccgtcaccaa ctcgactgaa tgaccgagct gagccaaact agccaaaaca tttaactccg
    12541 aaccaccaaa ttgacactcc aagctcctag cctgtgtcaa agtctgataa tgtgggggag
    12601 atagtcgcaa taaaacttct ccaaatgcta aaattttctt cataccgcct cctagttgaa
    12661 agacccagct ggaagcctcc aactaggtca atcattgtac tatttacatt caaaaatctt
    12721 atttatcttc gtattgttca accttatact gagttacatc aacgtagtcc atatcagata
    12781 gtggaacatt tttcgcaata gcacgcactc gttcttcatc ttttgccgct ttcatgacat
    12841 ggattttctc ttgaatacga gccatttctt cacggtctag tttgtagaat ttcatcaaga
    12901 acaaggatac gctcaatacc gctgctggaa ttactgttaa caagacaatt agtgccattc
    12961 tcaaatcagt tgagaaagct gtttcaacag ttggatattc tttaccaaat ccaatacctg
    13021 ctaacacaaa accaacaacc attggagcaa atgaagacgc aattgagtct gtcaatgaga
    13081 agatagtacc aatcatacct gacaagtaac gaccagatac tgatgtttca tagtctgtaa
    13141 tatctgcacc cattgtcaat accaaaccgg atggagcgcc agatgcataa cgtgcaatga
    13201 tataaacaac aaagaaaccg attgtgtaga gattccaatt tgttaaatcc aacataccag
    13261 gttttgctga aaacagcatc gctgccaagg caacaagacc agcaataccc aactgaagcg
    13321 ctgtaatata ggcaaagcgt aaacctttac gacgagccaa ctgtgccgca ccaactgtta
    13381 cgaggatacc aggcaaaatc aagagcattg acatttttcc agaaagagca tagtcaccga
    13441 agataatacc ataaagcata accccgataa ctgaatcacc gaacaactga gcaacaaatt
    13501 ttacaaaggc tgcagagatt gaaagtacct gcaaaggttt atttcctttg ataactttcc
    13561 agtagtcttt caacttagtt tcttgcgttt tttcgccaag accaaagtat ttcttattgt
    13621 ctttttccca aataccgata atagcaagga tacccagaat agctgaaata atcacaacac
    13681 caaggaacaa ttcttggaag aaacttggtg tgaagccacc atgtttagga accaatgttc
    13741 ctgatacaac aacctgacta ccagtcatca atactgttgt tgcaataccg tcaacaatat
    13801 tgaagattgg acgttgtttc ggatcattgg taagagcaac ctgtcccgct ttcgtaatag
    13861 tctgttgcaa tgaataacca attttatgga taatcaaaac aagtataaac aagggaagac
    13921 ggagattctc actaactcca cttaagccca acatcatgaa aagggaacta gccgtaatga
    13981 tattccccaa aaccaagata ggacgatatt taccaaactt agtatctgtt ttatcaataa
    14041 taacaccaat tgttggatca atgaaaccat caaagatacg aatatagccc atcagttggc
    14101 taacaaacag cgctgccaga ccaagcacac ccgtcgataa ataagtcaca aaagtaaagg
    14161 caaccaagta aatattcgtc gacgaattat tcatcgcaaa taagatgatt tgccataact
    14221 tcgctttgtt ataagtaacg tcttcgacac gttgctcaac atgtttttcc atcggaaatt
    14281 cctcctaaat gttttctacg acaaagtcgt aagcgttttc tttaactata ttctactatt
    14341 cgtcagatga tttgtcaaca gtttttgtaa atatttttaa ttatacgcaa aaaaagacga
    14401 ttttacgtaa aaatcatctg atatatttta tttaaacaca gccaattcgt ctgactattt
    14461 attgatttac tgtaatttcc ccactatggt agttgatact gagaccgctc tgcacattgg
    14521 gaacaaaaac attgaactct aggcttccat ctgccgcttt tgcttctagc tgactcccta
    14581 caggaaccag gtcatctgcc tctgcataga ccaaggttac acgatagcgg acacgcttat
    14641 ttttatccaa agcgcgtctt atttggctct cagaaaaatt ttgacccgca gagctttggt
    14701 cattagcttg gttagaccaa gctgtttgaa cagcaatgtt tttatagtaa agtgaaataa
    14761 gaataggaca aatcaatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagat
    14821 gtgtactatt ctagtttcaa tctactatag gattgctggt cgaagcatca aaacctgaaa
    14881 gtccaccaat caaggcatag cccagaaggt gacctcggtc cactgcatgg tcatattctc
    14941 cagttaagtc atggacctga tgccaaccag caggtgtcca agaagtccga ccatttctag
    15001 tttcttcacg atccttatac tgacgtgtag attttgctaa aagcgcattg gctactgtcg
    15061 gaatagtttc tccctgcacc gtttttgtct tgttgtctcc gtaaggaaca cttgcaacag
    15121 aggcatttaa atccgtctga ttatcgttaa taataaaggc tccagcacca ttccattcaa
    15181 tagaattccc cagttgcttt ttgacttctt ctgtcaatac cgaactagct agttcctgac
    15241 taggagtccc ttcactcgcc ttagactgat tgacataata ggaataattg gcaggagtgc
    15301 tactctggct atcacttaaa agataaccac ccgctactgc aattatagtc accagtaagc
    15361 tcattgcctg ttttttcaaa tttttcttcg ccattttctc tccatcaaaa aagcaggacc
    15421 agcctacttt cctgtaaatt taccgattaa ttcctgccac ttagcaggtg acaataccgc
    15481 aaatacattg tcaccatcac ctatgacacc ataaccaagc actaatccta acacaaatac
    15541 caaagcagca attaacaaaa caattaccac caagagcaag tttttgccaa catagctgag
    15601 attttcctta tccattttca acttctccac tcacgcgttc aaatatcatt tttgagatta
    15661 agaattgtca aaaaaaatag ctagcaagga aaaaccaaca aatagcatcc aagtcaactg
    15721 catgttccat acggctacta gtgaaaaaca agctgttccc acaggtatgg ataaggtaaa
    15781 caatagaccg aaaaaattac tagtacgagc tagaacctct ggagctagat ttttcatgag
    15841 catggcacta atctttggtt gaactttacc agacacatac agagtaaaga agagaaatag
    15901 caaaccaagc acgacttgat tgaataaatt agccaaacca actagactaa gtcctacggt
    15961 ctcccacatc atcaatctag gcaaggactg cttcccaaaa taatcattgc ccgtaaggct
    16021 actgatgata actgctacta aaacacagaa ttgattgata aatagtgcct ctgtataaga
    16081 aaaattcaag agagaatggc tcaaaaagaa gatattataa attccaccca aagcgccacc
    16141 caaggaatta ataagcaaga cagcaaagag cataaaacca aagtttttct gtccactttt
    16201 aagaaaaacg agacgtaaat ttcggtaaat tgttaggaac tggtctttga tagaaagctt
    16261 ctcatttttt agtttttcac catcagcaga tgacattgac aggctcaatt tgctttttcc
    16321 taaaaagagg atgacggctg atactaggaa gaaacaggca ttgattcccg caacgaggga
    16381 aaaattgttg accgatagac ctaagagcca gactccaaaa gcttgaccac caatagctga
    16441 aatataggtg ataaactggg aaaaagaata agcctccatc aaatcatttt cagctacttt
    16501 ttccttaata agaggcatgc gcaggccacc tgcaaaatca ctgatgatat cactaatgac
    16561 attgatcaaa cacaggctag aaaaggcaaa gagactagct tgctgaacaa ctagggctgc
    16621 tagaaaaaat agaaccgcct gaaacaaacc gctatagacc atccatttga ccttgtccct
    16681 cgtgtaatct gcccgaatcc ctacaaaaac tgtaaagagg gtcggaagaa tcatgacaat
    16741 attcgccata gcaacagcaa aagatgcttg tgacaaggtc gatgcataga cgataaagac
    16801 caggttgaaa atcgaagcac caaaagcatt gaagaagcgt gataaagtca aaattctata
    16861 agctggattt ctaaacaata gtttcataga taatctccct tcttgttcta agttctacat
    16921 caagaatagc tttagtatag cacttatgaa tttgcgaaac gattcttttg aatatatgca
    16981 acaaacaaaa tgagcaaaaa aacgatagaa cttttgtaat gacctgagag agggcaacag
    17041 ttctatcgct tcaaattttt tcttggtttg cagatactca acattcggtc gtatttctat
    17101 agtattcggc agatttatta cagccaagca tctcaaaaat acggacagca tcctccatct
    17161 ttttctgacc ttccttgact ctaccttgct tgctatcaag gagaccttct gcccacagat
    17221 aaacaattcg gaaataggtc tcatttccct tgtagaaatg ctcttcgata acacgtttaa
    17281 aataataggc attggtaaat tcttcacact caatactagc taaaaagcca ttcaatagta
    17341 tagtatgaaa aaggtttcga ttgccagaca tttccattag aaaatcagat ttatgtacca
    17401 tttctcgtac atatctagta aaaagagaaa cagataaaaa tggaaaactg actgaaaata
    17461 aattgagttc atagattccc cagatctcgg tagaaaacaa ataatcatga aggacttttc
    17521 cttcctctgc tgttaactct accctttcat ctatgctctt catataagac ttgataataa
    17581 tggcatttag aatatgtttc tgtttgttgt gagaatgggc atgcttttga tactccctgc
    17641 gatataagtc ctcaagaggt gctatattct ttggttccaa gacatctgta atttcttttc
    17701 tcaactcaga atctgtatca tactggaaac ctctcgccag aaagaggatc tcctccacac
    17761 tggcagatat attttccaga gcaaatagaa acttttccac cgaaagctca ctctgacctg
    17821 tttcaaaacg ggacaacata gacggcgaaa attgtcctcc ggttgcttgt ctcagtgaga
    17881 tatttcttga ctctcgtaat tgtctaaaga cttttccaat ctgctccata gacttcccct
    17941 tgattccgta ttttcttcat tttatcatat ttttcagaaa attcatcaaa aacttgccaa
    18001 attgtcagaa ttatgagaaa atagaggata tttatcacgt ggagggactg ctatgagaga
    18061 cgatatcaaa atcaatgacc gtgctttggc cttgcaagac caaattatcg aaaaactaga
    18121 gaaagttttt gatacagatg tggaattgga tgtttacaat ctaggtctga tttatgaaat
    18181 caatctggat gaaacggggc tctgcaagat tgtcatgacc ttcaccgata ctgcctgtga
    18241 ttgcgccgaa agcctgccta ttgaaattgt ggcaggtctg aaacaaatcg agggtatcaa
    18301 agatatcaag gttgaagtta cctggtcgcc tgcttggaaa atcacacgaa tcagtcgcta
    18361 tggccgtatt gcccttggac taccacctcg ttaagcaggc caatcacttt taaagatgaa
    18421 aaaagcaagc cgaaaatggc ttgctttttg atactcaatg aaaatcaaag ggcaaactag
    18481 aaaactagcc gcaggttgct caaaacactg ttttgaagtt gtggatagaa ctgacgaagt
    18541 cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagct caaaacactg
    18601 ttttgaggtt gtagatagaa ctgacgaagt cagtaaccat acctacggca aggcgacgtt
    18661 gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt gtccatattc
    18721 cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata tttaccgagg
    18781 acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc aagttcttct
    18841 tcggatacgg ccatggaaat ttctttggta tcttggtcaa ccgtaacgat atcgccggta
    18901 cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc aacaaccaga
    18961 ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc tccctgacct
    19021 ttaccaacaa tcattgatga aagtgacagc atctcaggca taccaggacc acctttaggt
    19081 ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag aacggcctga
    19141 atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg cactttaaca
    19201 cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat gataagcgga
    19261 ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg agtcaagtct
    19321 gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg atctccgtga
    19381 aggaaaccat ttgccaacaa gtacttcata accgcaggga caccaccgac ttcgtagagg
    19441 tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac acgttcttga
    19501 atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat ggcgagcaag
    19561 tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc atcttcaaag
    19621 gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt aacaacagca
    19681 cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg agaggatgac
    19741 cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc agtatacata
    19801 ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac gtcctcagct
    19861 gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa gtcgatatct
    19921 ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc tgggatatcc
    19981 atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc gatagcgacg
    20041 aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat gatgtcacga
    20101 gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc tacggtaatg
    20161 gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc cagtttcccg
    20221 aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat cactcccaca
    20281 atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc acggttaggt
    20341 gatttaacca tgctgtcata gatgctactg cggtgacgtt tatctaattc agtcatctta
    20401 tccctcccat ttcagttttt actattatag cacaatttaa aggcaatgaa cagaataaaa
    20461 ttcttgaatt ttcagaaaat tctatacgca tgtgaaatat ttaaaattaa aaacaacaaa
    20521 gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt ctttaaataa
    20581 cgtaatgtaa tttttacaga aattctttca gataagtgta tttaacatct atcttgcatt
    20641 ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact cattaagaag
    20701 ataatccatt ttccctactt gaccaaatct ttcttgaaca cccatccgat gaatttttgt
    20761 tattccatca tcagagaata attcacataa agcactgcca attccaccta tctgattgtg
    20821 gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt ctggtatcgg
    20881 tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca gttcatctgc
    20941 aactcgaata cttggagcaa ccattatacc agaagcaacg attacaagat cttcaccatg
    21001 ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag gaactggagc
    21061 ttttctaatt gttcgaatat attttaatcc ttttaagtct aatgtctggt tcaatatttc
    21121 acgaaattgg atatcatcag ttgcttcaaa aatgatcgat ttaggaatta aacgtaacaa
    21181 tccaatttct tcaaatggca tatgtgtccc gccattcatt tctgcagtta ctcctgcatc
    21241 tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata attgatcaaa
    21301 tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc cctgaataga
    21361 caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca cataacggtc
    21421 tccaaagtcc ttttcaagat tatgagtagc catcgaactt gacaaatcgg cttctaagac
    21481 tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata catgccgtaa
    21541 ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct ttctacaact
    21601 gaagttaaca tttgtctctc ctctacagta gggcgaagat gatggttgga tttcatttct
    21661 tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt aggtgatgaa
    21721 ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc tgaacccttg
    21781 accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc tggattacaa
    21841 atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac aattaagttg
    21901 gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc atttaactca
    21961 ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg accatatgca
    22021 agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc tatgcctggc
    22081 gttagatttc tatcaggatg agacggtaat ttggttccat ttttatttaa agaatataag
    22141 aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg tcctccatga
    22201 ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg agtcattggc
    22261 attatttcac cataaagcac tgctaaaact tctacgatag acaaacttcc tccgtaatgt
    22321 ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt cgcaaatttt
    22381 cttaactcat cttctctatt tttacttaaa atcatccctt attcctcctt tgcagatggc
    22441 tttttaataa aggatactcc aaacataact gctaaaataa gaacaagacc aatcacaatg
    22501 cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag accaaaatct
    22561 gcatctgaga aagttgatcc ttggaaaccg agtcctccca aaactggcat taaaaagact
    22621 gggagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc acgaacacca
    22681 ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg tacaacgcct
    22741 ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa accaccaaca
    22801 aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac aatcggacaa
    22861 tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa ggctggaaca
    22921 atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc tgcaaattga
    22981 cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc tttttctata
    23041 tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga taaagtgata
    23101 ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc ctctgttgat
    23161 tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc caaagaactg
    23221 aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt ttgcacaaat
    23281 gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat aagaggcaag
    23341 ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata tagagtgtgg
    23401 tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat attgaacacc
    23461 atgcctgcaa acataatcag tgcagtagct gagccatatg ttgttaaagc tacagctaca
    23521 attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa catggtacca
    23581 aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa gaaaccaaca
    23641 aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag aactaatcct
    23701 aaaattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa tatgaacttc
    23761 atcataacgc tagcctccta tataagtcct ttttcttcac aaagtttagt aattaattct
    23821 cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag atgactagct
    23881 gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc tgctccacct
    23941 aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac agattcaata
    24001 ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc aatttttaac
    24061 attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt tgatgatatt
    24121 aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa agcctttaaa
    24181 tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg ttctggatta
    24241 tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc attcacacct
    24301 tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa aggcccaaac
    24361 tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc ttgatccaaa
    24421 agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga actaacctga
    24481 taggtttctt tggtaatgag ttgttctagc actggtacaa tttcctttct atcatttttt
    24541 tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat aattccatat
    24601 cttttgacaa tattcaggat ttgttcaatc tcaaaatccc catactctaa attcggaaaa
    24661 tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat aaccgaaact
    24721 agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc atagtcacta
    24781 ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat ttgaggaaat
    24841 aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg acaaatgatt
    24901 gctgctttat agcatttttg aggcaaagta tctgctttct ttaaataacc tccgaaatgg
    24961 ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc catcaagggc
    25021 atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac atgcaataca
    25081 tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat aaggtggcgg
    25141 cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat atcttccatt
    25201 ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc tacttcacct
    25261 tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga aaacaccgta
    25321 tctataattc ccaaatcaac cactgtatcc aataaaatag tcgttatatc ttgaataaca
    25381 ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata cctacacaga
    25441 atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac tagctgtagc
    25501 ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga atacccccaa
    25561 ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa ctcactaacc
    25621 atttgaaaag ctaaacggtg cttattccac tctgaaccgt gtaaagtata accttttgct
    25681 ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga ttgaatatca
    25741 gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt cgatataaaa
    25801 tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt tggtaaaacc
    25861 aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga taaactatag
    25921 cgaccttgct ttttatccag cactatccct ttattagcta aataaggcac taaataatct
    25981 attccttctt tgacttcctt tataggtaag ctcaccttaa cagataactc atataatgat
    26041 acctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc aaacatttct
    26101 cttcctttct aactacaatt atagtgtaaa agttataaga ataaaagagt atttgagcac
    26161 aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg attatttttc
    26221 aactttctat tgacttttaa aaacaaagtg atatcattta gatatcaaat aatgggaggt
    26281 cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg cattgattct
    26341 cattgaattg acgctcgtac ttggtatctt tatatttata atgggtgttg gttcggaaaa
    26401 catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag ctcatgctgg
    26461 tttaaaagtt gtcaaacctc aggaagctct ggttctgaca ctctttggta attatacagg
    26521 taccatcaaa gaacctggtt tttactttgt caatcccttc agcgtagcag tcaaccctgc
    26581 aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt ttttaggtgc
    26641 taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaca tttccctcaa
    26701 agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa accctgtaga
    26761 aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct tcaacgttga
    26821 taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata ttgtccgcat
    26881 ctatccttac gatgtgtctc ctaatgtgga tactacgggt gacgggcaag cagatgaagg
    26941 tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa tccaaagtcg
    27001 tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag cttatgctcc
    27061 agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg atgcacggaa
    27121 gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc tcaatgaagg
    27181 ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc tccttgtcgt
    27241 tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagtcttt actaaagatg
    27301 gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata cgctgcactc
    27361 gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata tctcctcaca
    27421 gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat tgacgaacca
    27481 tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag aattttttca
    27541 tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctaa tatggttgat
    27601 gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa tggcagtacc
    27661 tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca aagtaacagc
    27721 tccatctgta aactttgacg aaactactgg agattactca cgttctcacc gtgtatcact
    27781 taaaggatac tacaaaggac gtaaaatcgc taaagctgca tcagctgaat aatagaaggg
    27841 agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac gcttgtacct
    27901 tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat actcaccaaa
    27961 acttcgcaaa cacgttgtgt ttacagaagt gaagtaagca ttcaatacga atcaatacag
    28021 aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactatatt gcaagggaaa
    28081 tcattcgaat gactaccttt tttgaaataa gaatacggat tcggacaatt aaaagcaaga
    28141 ggaactcaaa tgtaagttgg ggttcctttt ttgtatattt ttcaaataac gcctctacac
    28201 tatttgtagc aaattcacca actacagttg tatcttagtt aaaataagtt agaatatgta
    28261 agtgagtacc agatatacca agacatcgtc accatctaag gtatattcaa aatacaaaag
    28321 ttgaccaact agatttctga atatccttat atatccattc ttaaaattgg tttaaatagc
    28381 gtagtctttt aaactagttt taagaatcca aaaaatcttc ctacatatgt aagaagattt
    28441 tttagttcag aatgattaga tttagctaat ggatacctat cctacccact caccgttagc
    28501 attgactcga tagccatcgg gtgtagtcgt gtttactaat aaatctcctg aattataggt
    28561 atagtaccat ttaccagaaa ctgtaaacca accagtagcc attgaacctg attcgtttaa
    28621 gtaataccat aagcctttgt ctttaaccca accagtagcc attgaacctg attcatttaa
    28681 gtaataccat aagcctttgt ctttaaccca accagtagcc attgaacctg attcatttaa
    28741 gtaataccat aagcctttgt ctttaaccca accagtagcc attgaacctg attcgtttaa
    28801 gtaataccat aaacctttgt ctttaaccca accagtagcc attgaacctg attcgtttaa
    28861 gtaataccat aaacctttgt ctttaaccca accaactact ccctgattag aattcttttt
    28921 aggtttagct acatcagttt cttgttttat attatctact ttttcaacaa tgatatcatt
    28981 actagtagat aaatttgatt taagaacatc ttttatatgt tctgatgtta catagaactt
    29041 aacagtttca ggaattgcaa atgtatcttt tttcacagaa aactctgtac ttttattctt
    29101 aatatgaatt tcctttaatg aatctaagac gccacttagg aagaaggacg gcaatgagtt
    29161 gatattatta ccaattgtta aactttttaa ttttggtaaa ccgttcataa cgtgtttacc
    29221 aaaattttta acattatctg gtaatataag ttcttttaat tctaaattac cgtaaaaggc
    29281 taaacgttca atagtttcta aactatttgg taagctaatt tcttcaagtt taatcgcatc
    29341 cgcaaatgca aaagtaccga ttttttctaa accttcattc aattcgagtt ttttcaagta
    29401 agaattttta ttaaacgaat atgatgcaag ttcttttgtc tccttaggcg ttttataact
    29461 ttcgtcattt ttttgacttg gataataaat taattgagtt ttatcttttg aaaacaaaac
    29521 accatcaact gaggcaaacg attcatttcc ttcttcaaca tcaacatgtt ttaagctagt
    29581 agtgagtcta aatagattac ttcctaatgt tttaaccgat tttggtaatg ttagtttctc
    29641 taaatttgat aaattagcaa aagcctcatg tgatattaat tctaattttg aacttgagga
    29701 aaaggttagc tttttcaatt tttgactaaa agaaaatgca cttgttccaa tatattctag
    29761 agatgcaggc aattcaatct cttctaattc agaaaaatca aaagctctat cttcaatttt
    29821 ctccagctga ctgcctttgt caaaaataat agttttagct ttacttccat ggaagccttt
    29881 tttttgtatt ttttttatgc ttgatgggat agtaatagag ctaggatagt agacaattct
    29941 acctgtttca tctggataat aactaaaagc ttgactagct acttcagtaa cggtaaatac
    30001 tttatcacct actgtgattt ttgtaggaat cgtgaatggt tttccatctt gaccagcttc
    30061 aaactctaca ggagtaactc cattacccac ttgaacagtt cctatgttac cttctacagt
    30121 tagaacctta tatttgatat tattttgttg aataatactt ccaactttag tctctttgat
    30181 tacttccgaa ctaggagtat ctgctaggat tggttcatta gggacatatg ctgctaaaat
    30241 aaccgcagct gtagttaatg ataatattgt agtttttttc atttaaattt ccttacatat
    30301 ttattttcta atagatataa aattataact ttgctagccg ttgttataaa aagttttatt
    30361 caatcattat ctagtagaat agagtagtac attttataaa ttgtcatctc tccataaaca
    30421 cagtatatca tttttaaatt ttaagtcaag gaaaattaac ccactttaat ttctttttta
    30481 acccgtgtta aaaaagaaat taaagtgggt taaaaaagaa attaactgag taaaaactct
    30541 cgaaattcaa ttcgctatat tatcactcaa ctttaacaaa taccagaacc acaaaaaaca
    30601 gatgtaaagg aaaaatatgg acttaaaatt tgaaggggtt gatttagaat acaaaaaagc
    30661 taaaaacaat cttccagagt ctttctggga aacctactca gcatttgcaa atacaaatgg
    30721 cgggaaaata attctcggga tagatgaaaa aaacattgac acctaccaaa gagtcaatag
    30781 actccctgcg aaattatgaa gcaagtaaac aattaactga tacacgattt aagcgtcttg
    30841 ttggtgttca gcgcacgact tttaaagaga tgttagctgt attaaaaaca gcttatcaac
    30901 ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct agaagacctt cttatggcca
    30961 ctcttcaata tgtacgagaa taccgcactt atgaagaaat tgcggctgat tttggtattc
    31021 acgaaagcaa cttaatccgt cggagccaat gggttgaagt aactcttgtt caaagtggtg
    31081 ttacgatttc aagaactcct ctcagctctg aggacacggt aatgattgat gtgacggaag
    31141 taaaaagaaa tgccacgcta tgaaggctca ggcgattgtc acaagtcaag ggagaattgt
    31201 ttctttggtt atcgctgtga actattgtca tgatatgaag ttgttcaaaa tgagtcgcag
    31261 aaatatcgga caagctggta aaatcttggc tgacagtggt tattaaggac tcatgaagat
    31321 atatcctcaa gtacaaactc cacgtaaatc cagcaaactc aagccgctaa cagctgaaga
    31381 taaagcctgt aaccatgcgc tatccaagga gagaagcaag gttgagaaca tctttgccaa
    31441 agtaaaaacg tttaaaatgt tttcaacaat ctatcgaaat catcgtaaac gcttcggatt
    31501 acgaatgaat ttgattgctg gtattatcaa tcatgaacta ggattctagt tttgcaggaa
    31561 gtctattgaa atactaagcc tacacagact gatttcaatt ttaccattct tcatagtcaa
    31621 aaccatcata atctagatat tgttctggta acgttcttca acatcgtcac taacaaagct
    31681 aagaaagtaa gaatctgcat gactccactc aacattatcc atgaaaaatg catgagcatg
    31741 atcatttaca aaatcgaaac tccataaaat cacatctgct agttccgcta acgtttttgt
    31801 ttttggaatc tatatatgtc ggtagtaacc ttttttaatt tgacggaaat gatccaagct
    31861 tctacagatg ctggcttttc agcttctatt tcttgtttta ctaattttaa gtgtagcata
    31921 atacctccaa ttgctcatcg atagaattgc tcttaggaaa cattcacttt ctgctatttt
    31981 atcataagtt tgtctaactg tagcatttga aaccagataa ttcttctgtt tcacgcgaaa
    32041 caccctgcgc caagcaagat gttcttgttt ttatactcaa tgaaaatcaa agagcaaact
    32101 aggaagctag ctgcaggctg ctcaaaacac tgttttgagg ttgtagatgg aagctgacgt
    32161 ggtttgaaga gattttcgaa gagtattaag tcgtataaat cgtcgaagct gtcgcaatgg
    32221 tatgccactg gttaactgta gttgctgcga aatccttgtc tgcgtagaag tcagtaaatg
    32281 gtaggatttc aacttccagc tcgtcgatgc ggtcaagctg gccagccaga taaacctcga
    32341 tacggctttc tgctcgtttg atgcgttgca agagtccgcc catacggatg tcaactgtat
    32401 ccaaaccaaa gaccttgttt tctttcagcc attggtgact aaagagggca tggaagtctt
    32461 caatttggct tctaagttct ggtaattctt gtctggcgat ttgttgtaaa ctttctttat
    32521 catccgcttg gtaggcctga cgaatgcgtc gtcccacatc tactttgcta cttaaaatag
    32581 cattcaactg ggcctgagtt tcaaagagat aagcatagtt tccagctttt tctttaatgt
    32641 tagcaagcgt ctcagcagcc tgagcgaagt gcggtttgtc ctgttcaggt gtcatgtgtc
    32701 ggtcaagtat cggacaaaga acatcctgat aaaaaacata gcggttggga ttgataccgc
    32761 tgagattgcc tggtaggtct ggtaagaggt tggcaaggtc aatctgcata aaatcctcaa
    32821 ccgttagacc agtattggtc ttgaagtgcg cagacaaact atctaggtca ttgcgatagc
    32881 tgagttctgc ccagatttgc aagcttgata ggatagagaa ctgggcagtt tcactaccat
    32941 tgtctcccca acccgttacg atgacttctt taatctgatt ggcacggcag gctttattag
    33001 cctcgatagc cactagacgg ctaaaatggt tgtgaggtgt aaagccaatc cacttccaag
    33061 ctccccctgc aaatgcaagg tcatggctaa tcttgtgatg attgcggaaa ttacggttgt
    33121 atttttcctc gctatcctga taataatccc agtaaaccag agtcacacgg tctttgagac
    33181 ggtctaggta gacacgagtt tcctctggaa tttccacatc acggtcgtac tggccatccg
    33241 ctgacatgag tttgaagaac atatcactcc acatctggca gtggaaacca tatttgtcag
    33301 caatatccag cacgcgctcc aagtgttggc acatgaggag actacgatcc acaacaccgt
    33361 tcaaaatcag gtagcgtccc aaaccaacca agtgggcttc gtccatcccg atattgacct
    33421 tgcgagtctt cagtttagac aacgtggcaa acatgccatc aatcaggtca taaacctttt
    33481 cttcgccaat gagaagaatg tcctctacat cacggagctc ctgcacttcc ttgacacccc
    33541 atttgacaaa ggccgacaag tgggccaagg tctggatgca tggtacaaag gtcatgtcaa
    33601 actgttgggc ataggcttcg atttcctgca actcctcagc tgaataagct ccacggaaat
    33661 agccaaagta aggctgccct tcaatctggt aagtgtcttc catgtagagc tcaaaggttg
    33721 agtagcccat gagagccaat atctcaatca tctgcttggc agaagcgaca ttcagcaccg
    33781 catttcgaga acagtcaacc atataagcca aatcttcata agctgcttgt tcctcaatct
    33841 ctactttatc agcttctgct agaactgtta ccaacaagga caaggcacga taaagttggt
    33901 gaggtttgcg gtaggtcaat tgatagtgac cttcctcacc ctcgatagag atagaggctt
    33961 ggtcagactg agtgacagcc acttccacat ctggtagaga aatgtgacct tttaaaacct
    34021 caatagcttg cgtttgtttg ggactaagtc ctataaatct taccattgct tttcctcctg
    34081 tagccagttg acaagggcac cgtagagatt ggcatctgcg tgataggtgc aggcctggat
    34141 aactggtgcg accgtgtatt cttcgtaggc atcgacaaag ttatcaacag ccttcttgac
    34201 accttggata aaatctggat tttgactgat agagccaccc agactgatga catctggatc
    34261 gatgagatac tggatattga gcaagccttg cgccagattg cggttcatgc gctcaatggc
    34321 ttcttgacaa agagcattac cagctgcggc ctcttggtaa atcttgcgac cgtcccaatc
    34381 agtatgacca gatttttcaa tcacgtatcg taccatattc ccagttgatg ctagttgcga
    34441 ccagttatta agtttttcag caggggcaag ggttgtcatg tagccaaatt ctccacccag
    34501 accgtggcga cctcgatgaa gtctaccatt gataatcatg gctccgccaa tccctgtccc
    34561 aatcacgaca caggctgcat tttcaagctc tggatgagct agtagttcac tgagtccaac
    34621 gcagttggca tcattttcca gatggacagg tagctgataa gagctaagcg cctcatacca
    34681 agaaaagcca tggatgtagg gcaccgcact gaagccatca atcacacctg tctcttgatt
    34741 gaccgcacct ggaacgctca tagcaatccc actgtaatcc tgttctgaca agcgttgatc
    34801 tagccacgct agtaaatcct ccaagttttc aggcgttgaa atacttgtct tatccagtat
    34861 tttcccatca ggagtcagac tggcaaactt aatcccagtc cctccgatat caatcgttgc
    34921 aatggtcatt gtttttacca taaaaagggg cgaatcagca gttagttctt actttttcgc
    34981 ccctcctttc ttttgatgtt tactttttga aattaaattt cttctttttt gatgaattct
    35041 gtacgaatct cttgtggagc caatagtcct gaatgaactg gatatggtcg ctcaagtaag
    35101 tcaagaatgg tttgttgatg ttctgatatg cgcacatttt cttgactcat attatagtaa
    35161 cggaggacat agccttcttc attttccgcc actttaaagg ctgttggaca aacttgcggt
    35221 atgctgagaa cagaatggct caagaggcta ccagtcgcaa ccacgcttcc ttcctgtcta
    35281 gcaagctgaa ggctggtaaa cggtgtctgc aaggctttgg cacgacgata ggctgagaag
    35341 cgttcttggg cttggtggca ttcaagtgca aactcgactt caaactcccg caagcattgt
    35401 gcttctggcg ttgggaagta gccccagtca cctagctcac ctgatgcacg caaaatggtc
    35461 acggcaatgg tgttatcccc aaggatttcg tattcattca atcccttatt ggatacagtc
    35521 accccttttt catcgtcata cagactgaca aaagcttgtt ggtgttgagg attttcaggg
    35581 ttttcccatg aagcagctgg tttgtttggt cgtgtcacca cctcatagat actttcagaa
    35641 tcattgcttg gacgcgtgtt atgagtcttg accaagagac ggatacggtg atccttggca
    35701 gtgttagtaa agcgagtctt gaagcggatt tgtggattgt caacgaagac agtcaactca
    35761 gtttccagag gaatgtttgt caattcttct gaccgtccag cctcacgctt cataaactcg
    35821 atgatacctt gttgctcttc ttctagcttt tcatccgcac tgacaggcac ggtcaattca
    35881 tgtttgagca agattttagc atagcaagct gtgttttcca agacctcgtg gcccttaagc
    35941 tctgcaaaga ttggctctgt tccttttggt tggaaataga tatactcgtt tccgatgtcc
    36001 ccacggtctt caaagcggat aaagtcttca taggcttcgt gagttgtctt gtcatagact
    36061 gtgatgttgt catccacact caccgttacg aatggtgtat caatcactcc gttttggtaa
    36121 ataccctcac ggtgttcttg ttttccttcc agcaattgga aggttgtcca agaaagcggc
    36181 gctaggtgaa ctggaatggt cacgcgcact tgtcgagcaa tacgagcttg gcggaactta
    36241 tcttttggta aatcgtactc aaaattagct ccgaggtctt cgattgtagc ctctacagga
    36301 cgaccatcca agtcctccac acggtaactt ggcaagataa gagcagccat ctttttgtag
    36361 ccttctgttg ggtgcaattc cttgaaatca caagtcgcca catcaatcac tgtgctgaca
    36421 gtatcgacct tatcatgcaa gcctgtgtta atgacagtaa agagatagtc actttgagcc
    36481 ttatccgtag caattttacc cttccactcg ttgagcaagt tacttttaac aaagtttcct
    36541 acttggttga ccttggcaaa acgcgtttcc atctcgcggt gaacttcgtc cacgctacag
    36601 ccacagatac tatcatgtgg cgcgttctgc aaaagtgttt tccaagcata ggtcaactgg
    36661 tccttgtggt tgtgtccacc agtgataata gtcaagggtt ctaccacttg ctctaggagg
    36721 ttgctatttt cttggaaggc ttgttttagg taaatgcggg atgaagaagt gttggcaagt
    36781 gtgtaccagc catctgtttc ctgactggtc aactcgcctg taacagttga taagtgttca
    36841 ggaagcgcac cttctacagc ttgaacatat tcatcaaaag aactatgaac aaagattaca
    36901 tccgggaaga gttcatttgc cacacgaatg gcttcgctca gatttttctg tacaggctgg
    36961 tggtcacagc cgttcatcat caaccattgg ttggtcgaag cgtaggcacg cacatctgac
    37021 aatttttgtt tccagaaggt caaggcctca tctttgtcaa ctgggatttc attcccatta
    37081 ctgtaccagt tggcaaagag aatacctaaa acacgactac catccacacc ctgccagtac
    37141 atttctgaaa actgggatgt aaactgctca tcttcaagga cttggttgtc aaatccaatc
    37201 ggcttcacac cacgaccaaa ggccgccaca tgaatgcctg atttttgaag aatttgaggt
    37261 gcttgtccca tatttccaaa ggtatctgga aagtagccaa tctgggttga tttaccccat
    37321 ttggcagctt cttgttgacc aatcaaggta ttgcggacat tggcttcact tgaaatcaaa
    37381 taatcatcct gcaagatgta aaagggacca attttaagct tgccctcgtc aatgtagcgt
    37441 tggaccttgt cgcgattttc agggcgaatt tgtaagtagt cgtcaaggac aatagtttgt
    37501 ccatccaagt ggaaactctt gaactcaggg tcattttcaa agagatcaaa gagattgtca
    37561 aacaattcca ccaactgcat acgatgactt tcaaaaggca agtaccactc acggtcccag
    37621 tgactatgtg agataatatg tacaacaaca ttttccatga agtaaaacct cattctaaat
    37681 ttaaatttta acgttttaaa tgtaaacttg tgattctgat aagaatcggt tgagctaaag
    37741 cgagcccctt agcgaatatc caagtaatcc aagaccaact cacagaacat catgttagcc
    37801 caggagaacc attcacgaga gtagagagtt gggtcatcca cgtggaagct ttcatgcata
    37861 agacctgtac cgccatcgca ggcaaccagc tgatccagca agaagttttt ctctgcctta
    37921 tctcttgttg tcaagccttg gatagaaagg gcgattggcc agatatagcg atagaaggta
    37981 tgagaacttc cgagaccgct agcgtattct ccttggtaga aatatggatt ttcagagctc
    38041 agaatggtac ggcgagtagc ttgatacact tcatcatcga ccgaacagta gcccagatag
    38101 ggcgcagcta gtagacttgg tacgtttgga tcatccataa tgctggcatt tcctaggcca
    38161 tctacttcaa aagcgtaaat cttttcgccc ttgctgttgg tggtgtaagc gtagttttcg
    38221 attccttctt ggatttcatc ctgaagacgc ttggcatcag caataacact ctggctatca
    38281 gctaggttta atgctgcgaa gatttcttgc acataaccca agactactac agcaaacata
    38341 tttgacggaa tcaagtaact atactggcaa cagtcatcac tcggacgaaa ggctgaccaa
    38401 gtcatacctg tcactgcaaa gtcaggtcca aagccatcat ttaccaaggt gtcttcctta
    38461 cggtccgtat ctcggacaaa acgataagga gagttcttgt ggtcttgttc aactgtccat
    38521 agatggagaa tttccttagt cgctgcgaca aaagtctcat caaactgact agtctcgcca
    38581 gtttctttcc agaggagata agccaactgc aaaggatagc aaagcgagtc cacctcatac
    38641 ttgcgttccc aaatccagcc attaaggtcg gtgtggtcgg tctcgtggtg ccccttccag
    38701 ttttcctcta tgttgaagga attggcataa ggatccttga gtaccaaggt catctgacgt
    38761 ttgaccaaac ctgcaatggt ctgacgcagg agggcatctc ttttagctac atgcaggtag
    38821 ggtctgagtt gggctgtcga atcccgaagc cacatagcag gaatatcccc agtcaagaca
    38881 aaagttgaac catcttctaa gatttcaacc gtattgtcca aggtatcggt gtagcaacgc
    38941 tcgaaaacat ccacccactc tggatggtcc ttagcccgct ctgctacttc atctagccat
    39001 tctctaacaa tttctttcga ataaatcatc gtgcaattcc ctctttcaaa caagtttcat
    39061 gttcagtata tagcttttga gacagaaaat acatacacaa atgatagtca tttttctaca
    39121 aaatagttat ttttgaaact ccttttctaa aggccctctt tttctgatat aatgtagaaa
    39181 aacagctaaa ggaaagacta tgaaaccact acttgaaacc atcgataccc gcttgggaac
    39241 taccaatagg catgcctttt ctcggggaaa taccctgcca tacacaggcg tgccttttgg
    39301 gatgaattac tttgtgcccc agaccagtga ccaggatgga gcttggtttt ttgatccgca
    39361 tctgcctatc tttcagggga ttcgattaac tcaccagccc agtccttgga ttggggacta
    39421 ctcttggctc cttctgacac ctgtcaccag tcaactgggg ggagacagcc tctttcaccg
    39481 ccaatcttcc tatgataggg ataaggcctc tttccaacct cattatctaa agattttctc
    39541 cctgcgctat cagattgaaa cccagctcac accgacttgc tatggtgctt ctattcgttt
    39601 gaagcaaaag caaggcaaag ccctctccct ctatcttcac gcagcagatg aactgacagt
    39661 agagcaagta gataagcgga ctcttgccct gcgacaagaa ggtaaaactg aaactaacaa
    39721 aaattcgcta acgatgttca ctgccctgca aatgaacacg gatattcttg ctatcagcca
    39781 agaagctgga gactggcgaa ttgacttagc aagtagtcaa accgagatgc aactagccac
    39841 ttctttcatc tctccttctc aagctctaat caatctacct caagaagatt ttgatagctg
    39901 taaagcaagt gcccaagcgg attgggaaaa tctcctccat cgttttgaca ttatagagac
    39961 aggagaggct gaccgaacct tctttgacca ctgtctctac agactcttcc tcttcccaca
    40021 gactttttat gaggttgatg agtcagggca agccatccac atggatctgg ctactggtac
    40081 tgtcaagcct ggtgtcctct ttagcaacaa tggtttctgg gataccttcc gcaccacctt
    40141 ccccctcttt gcccttatca taccggagca ctatcaacgc tttttagaag gtttcctcaa
    40201 tagctaccgc gatactggtt tccttccaaa atggctggct ccagatgaac gaggtatgat
    40261 gccaggtaca cttttagacg gtattatcgc agatagcacc tgcaaggaca tggcccccga
    40321 cctagaagga gaactcttcc aagccatgct cgaaacagcc agcaaagccg accctctcgg
    40381 aatcaatggc cgccacggac tagcccaata ccaagaacta ggttacctct ctaccgacca
    40441 ccatgaaagt gttagccata ctctagacta tgcctatagt gacttttgta tcgccagctg
    40501 tgccaaaaaa ctagagaaca tagaaatcgc tgaaacctac aaggctgctt cacaaaatta
    40561 ccgccagcta tttgacgctg agacaggtta catgcgagca cgagacaatc aaggaaactt
    40621 tcaccctgac ttctctcctt atagttgggg gcgagactac gctgaatgct ctgccattca
    40681 agctacttta ggcgttctcc acgacatccc tggcttaatc caactgatgg gtggaaaaga
    40741 aacctttagc aactatcttt tgaaaacctg tcaagatgct cccctctttg aaataacagg
    40801 ctatggttac gaaattcacg aaatgagcga gatggctact gctccttttg gacaaatagc
    40861 catttccaac cagcctagtt tccacattcc ttatctcttc cgttacagcg attaccctga
    40921 ctacactgcc cttcttatca agacgctccg tcagaaagct tttcacccaa gttgggaagc
    40981 ctatcctgga gatgaagaca atggtagtct ctctgcttgg tacatctggt cagctctcgg
    41041 attttatcca acctgtccag gaaaaccaag ctatgacctc ggaatccctc tctttgacca
    41101 tctacgagtc tacctcgcta aagaagataa atggctggat atccatacta aacaaaacca
    41161 caaccatttt aactttgtca aagaatgccg actggacaaa acactcgtat caactattca
    41221 acaccaagac ctcttaaaag ctgaacaact aactttcacc ctcagctggt taccaagtca
    41281 ctaataacca aaagaacctt tgcatcgcgc aaaggttctt cttttatgaa acttggactt
    41341 gaagttgatc cacaagctga ccatccaccg ttaggttcag atagaaatcc aaggttttat
    41401 ctcctgcgaa atacaaggtt ggtagcgtca gacttttttc agtctcacca gcttgaaacg
    41461 caaggacttg aatctcatcc tgataggcga caccatggac acctgtcccc ggttgaatcg
    41521 aaatcttagc ctctaaagag gagctacttt cactacgttc aatcctaaaa tgaagagtct
    41581 ctccctttgc cacagctagg cttttttctg caaatgctag ttcctgaaca acttcttttt
    41641 ttgataatcc aggagtttta taaagggaaa tcttggtcaa tacaggaata gattgtgcct
    41701 cggtaatcat cacgcgcacc ttctgtgcct ctactagcgg acctcgcaag aggcgcttat
    41761 gaccaactgt gaagcccctg ccaaattcct gccagacacc atccacctct acttgcacat
    41821 ggaaagcaga aatacgttgg cctaacttca aatcttctct caactcaatt acatcaaaag
    41881 ttttaggaga acctaagtcg agttctaact ggatgggcaa gtctgcatcg cttgcccaag
    41941 agctggtctc aaggccgtct gtcaaatggc gacaagcaaa gtctgcggaa agagttggac
    42001 cagatacctc agctcccaga gccaaatctt ctttatagag ctcattgcga taggtcacaa
    42061 attcataaag tcgttcaata tcctttgcat caaagagccc agcttgattc ggcggaatat
    42121 taagcaagag tggagttcct cgccctactg agtgaaagta gatttcgacc aactcctcga
    42181 gagacttagg atcctgatcc tcatggtaga accagcctgg acggatggaa acatctgcct
    42241 ctccgattga aaaaatcgtg cccgagggat ccccgtgctg aagatagtcc agctctgctt
    42301 ctgttcctag tttatcagga ttcacctttt gccacagtgg atcacctgca taccctcgtt
    42361 catttccaat ccatcggata ctggtgcctt ctgttgaaaa aatcaagcaa ttgccctgca
    42421 ggtcacgaat ggtttcaaac catttttcaa attcataatt aaccttttgc gcgccctctc
    42481 ctctggcacc atccatccaa acctcagcaa atttccctcc atttccatag gcaggatttg
    42541 ataagatttc cttcagctga gccagataat aggcattgta gtccgcttct cggtccacat
    42601 gatagaggag actatgggca tcccacggtg acaggtagac ccccatatcc atatcaaact
    42661 ctgtggcagc ttgggatact tcaaggagca agtcgccctt tcctctcctc caaggactga
    42721 ccttaaccga ataatctgtg tgagctgtcg gataaaggac aaagccatcg tggtgcttga
    42781 ccaccaaaat caactttttg aagcccgttt ccttgagcac acgaacccac tcacgcgcat
    42841 ccaactgact cgggttaaag cgctcaggat cctcctgtcc agtcccccat tcttggtcat
    42901 aaaaggtatt aggaccgaag tggataaaag ctgctagttc atctcccaga taagctagct
    42961 gagtctgact tggtaacggt ccatgcggtt tgattttctt catcgttata tatctccttc
    43021 tttagcaact tctcttgttc acaaggttat ccacaggttg tggataataa accatgatct
    43081 aacagccagc tctttccaac tccaactggt aggctcagga ttttgctcct caatattccc
    43141 tcttcaaaca gctctgtcat atggttctgc taacacctct cagaatgcta ctctccataa
    43201 ttattctcag gcttctttca ggtcattgtg tgaagaccat tcactctcca gacttttcca
    43261 cagattgtga ataagtgatt attctaaact atcacctcgt cgactataac aaaaaataaa
    43321 aagagggtca ataagataat tatctcttcc taaatactca gaaaagattc tataatttgt
    43381 acaattgaac aagaaatgct tctccaaaat ctatcttcaa aagaatgttg catcttttta
    43441 tcctttcaca caaacatttc tctttataca gatccaagtg ataaccagat gataattgga
    43501 cactttttgg ttatttgtgt attttttgaa aaatttttta aaaaaatttt atatcctctt
    43561 taatagaagt ttatgcattt gtatatatgt attccatcct atgttgtgta taataacata
    43621 aaattgtgct aaatatcata atttatatta ttttccgaga aattatagcc attgacatta
    43681 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    43741 ttttaaggag gaaaatacat gtcttcacat ccaattcagg tcttctcaga aattgggaaa
    43801 ctgaaaaaag ttatgttaca ccgtccaggc aaggagttag aaaacttatt gccggactat
    43861 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    43921 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    43981 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    44041 gccaacatcc gtgatcgtca aaccaaggtt gctattcgtg aattacttca cggcatcaag
    44101 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    44161 attcctgacg aagctaaaga tctaactgac ttagttgaat cagagtatcc atttgcaatt
    44221 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    44281 tcgcttaacc acatgtttgc agatactcgt aaccgtgaaa cactttacgg taagtatatc
    44341 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    44401 acgcgtatcg aaggtggaga cgagctaatt ctttctaaag acgtccttgc agtaggtatc
    44461 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    44521 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    44581 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    44641 gaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaatagt tgaagagaaa
    44701 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    44761 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    44821 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    44881 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    44941 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggt
    45001 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    45061 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    45121 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    45181 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    45241 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    45301 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    45361 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    45421 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    45481 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    45541 cgtaacaacg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    45601 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    45661 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    45721 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    45781 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    45841 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    45901 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    45961 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    46021 atggctgcta cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    46081 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatgtaatg
    46141 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    46201 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    46261 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    46321 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tctgattatc actcacggta
    46381 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    46441 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    46501 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    46561 taacgcaagt tgtcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    46621 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    46681 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    46741 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    46801 gtggcggtat tcccgtcatc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    46861 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    46921 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    46981 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    47041 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    47101 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    47161 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    47221 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatattag ttttttagac
    47281 tttaatatgg taaaacaaat ataaatagaa agcgttttct taaatgttta tttaagaaag
    47341 tagttggttt tttacacttt gttagacatc aggaggaaaa acaaatgagt gaaaaagcta
    47401 aaaaagggtt taagatgcct tcatcttaca ccgtattatt gataatcatt gctattatgg
    47461 cagtactaac ttggtttatc cctgcggggg cctttataga aggtatttac gagactcagc
    47521 ctcaaaatcc acaagggatt tgggatgtcc tcatggcacc gattcgggct atgctaggta
    47581 ctcatccaga ggaaggttcg ctcattaaag aaacgagcgc agcgattgat gtagccttct
    47641 tcatccttat ggttggtggt ttccttggca ttgtcaacaa aactggtgct cttgacgtag
    47701 ggattgcctc tatcgtgaag aagtataagg gccgcgaaaa aatgttaatt ttggtactaa
    47761 tgcctttgtt tgccctcggt ggtacaactt atggtatggg tgaagaaaca atggccttct
    47821 atccactcct tgtgccagtt atgatggccg ttggttttga tagcctgact ggtgttgcaa
    47881 ttattttgct cggttctcaa atcggctgtt tggcatctac tctgaatcca tttgcgacag
    47941 gtattgcttc agcgactgcg ggagttggta caggggacgg tatcgtactt cgtctgatct
    48001 tctgggttac cttgactgct cttagtactt ggtttgttta ccgttatgcg gataagattc
    48061 aaaaagatcc gactaagtca ctggtttata gtactcgcaa agaagatttg aaacacttta
    48121 acgtagaaga atcttcatct gtagaatcta cacttagcag caaacaaaaa tcagttctct
    48181 tcttatttgt gttgacattc atcttgatgg tattgagctt cattccatgg acagaccttg
    48241 gcgttaccat ttttgatgac tttaatgctt ggttgactgg tcttccagtt attggtaata
    48301 ttgtcggttc atctacttct gcactaggta cttggtactt cccagaaggc gcaatgctct
    48361 ttgcctttat gggtatcctg attggtgtta tttatggtct taaagaagat aagattatct
    48421 cttccttcat gaatggtgct gctgacttgc tcagtgttgc cttgatcgta gcgattgctc
    48481 gtggtattca agttatcatg aacgacggta tgattaccga tacaatcctc aactggggta
    48541 aagaaggctt gagcggtcta tcttcacaag tctttatcgt tgtaacttat atcttctatc
    48601 tacctatgtc attcttgatc ccatcttcat ctggtcttgc cagcgcaact atgggtatca
    48661 tggctccact tggagaattt gtaaatgtcc gtcctagctt gattatcact gcttaccaat
    48721 ctgcttcagg tgtcttgaac ttgattgcac caacatctgg tattgtgatg ggagctcttg
    48781 cacttggacg tatcaacatt ggtacttggt ggaaattcat gggcaaactc gtagtcgcta
    48841 ttattgtagt gaccatcgcc cttcttctcc ttggaacctt ccttccattc ctataaaata
    48901 gtgagtgagg tgattccatg aaaatagata taacaaatca agttaaagat gaatttctta
    48961 tatcattaaa aaccttgatt tcctatcctt cagtactcaa tgaaggagaa aatggaacac
    49021 cttttggaca agcaatccaa gatgtcctag aaaaaacttt agagatttgt cgagacatag
    49081 gtttcactac ctatcttgac cctaaaggtt attacggata tgcagaaatc ggtcagggag
    49141 cagagcttct ggccattctc tgtcatttgg atgttgttcc atcaggtgat gaagcagatt
    49201 ggcagacacc gccatttgaa gcaactatca aagacggctg ggtattcgga cgtggtgtcc
    49261 aagatgataa aggcccttcg ctcgcagctc tctatgcagt aaaaagcttg ctggaccaag
    49321 gtattcagtt caaaaagcgc gtacgcttta tctttggtac cgatgaggaa accctctggc
    49381 gctgcatggc acgctacaat accatcgaag aacaggccag catgggcttt gcacctgact
    49441 catcttttcc tctgacctat gctgaaaaag ggcttctaca ggtcaaactt tatggccctg
    49501 gatcggatca actagagctt gaagtaggag gcgcctttaa cgttgtacca gacaaggcca
    49561 actaccaagg tcccctctat gaacaggttt gtaacggtct caaagaagct ggttatgatt
    49621 accaaaccac tgaacaaacc gtaacggttc tcggagtgcc aaagcatgct aaggatgcta
    49681 gtcaaggtat caatgctgtc atccgactag ctaccattct tgctcctctc caagaacacc
    49741 ctgctctcag ttttcttgca acacaagcag gtcaagacgg cacaggaaga caaatctttg
    49801 gtgatatagc agatgaacct tctggtcacc tatcctttaa tgtcgcaggt ctcatgatca
    49861 atcatgaacg ttctgaaatc cgtattgaca ttcggactcc tgtcttagct gacaaggaag
    49921 aactagtaga gttgcttaca agatgtgcac aaaactacca actccgctac gaagagtttg
    49981 actatctagc gcctctatac gtcgcaaaag acagtaaact cgttagcaca ctgatgcaaa
    50041 tctaccaaga aaagactggc gataacagtc ctgctatttc atccggtggt gccacttttg
    50101 ctcgcaccat gccaaattgt gtagccttcg gcgccttatt cccaggagcg aagcagacag
    50161 aacatcaggc aaatgaatgt gccgttctag aagatttgta ccgtgctatg gatatttatg
    50221 ccgaagccgt ctatcgactt gcaacttaat caggcaactg tttctaccaa aaaaatcgac
    50281 cgattaatga actgcacccc aaaagttaga cagaataaat ctaacttttg gggtgtttta
    50341 ttatgaaatt gagttatgaa gataaagttc agatctatga actaagaaag caaggacaaa
    50401 gcttcaaaca gctttcaaaa agatttatgt ggatgtttct ggtctaaagt catctgaatc
    50461 tttgagatga gctttataaa tcgatttttt cagtttttgc actggtgttt cgataaactc
    50521 aaacttttta gccgtggtat tgcctgattt tatagtatat tgaaactaga atagtacacc
    50581 tctacttcta aaacattttt agaaatcgat ttgactgtcc tgaacgattt gtcctattct
    50641 tatttcattt tactatattt gagccacttc gtctttaacg gctttattca taagctcttg
    50701 taatttttct ttactatcaa ttacttctga ttttccgttg taatttattg taataggttt
    50761 taacttacct aatttctcga cacgctcatt aatttgatct tttttaaagg ctgcatatgt
    50821 ttttcctaag attttttcga aaatatattt atcagatagc ggtttgcctt cttcttcagc
    50881 ttggtttttg tattgatttg aaacataagg aacaaatcct tcatagtaac ctaatgctcc
    50941 cataagttca aaagcttgtt ttctaattca aaccattgca actcagattt cagcttttca
    51001 gataaatcct gctcatccaa ataatgactt gaaattagtg ctgaactcgt ttctgtatcc
    51061 tgtacaggct gatcacccat accagcaaaa aataaactcg ttcctagcaa gaccgaacaa
    51121 gctcctattg catatttcct caaagaaaaa cgctgctttc tctcaaattg aaattctttc
    51181 atcccatctc ccatcattca ttattactgt atattttgta tatcagaaat agtttgtatt
    51241 cacaaatctt tctagttatt cccttatcat tcctaattaa gggagataac atacaataat
    51301 ttttagttaa atgtatatcg atgttttttg tttttcttaa taaacgcaat acaaaaagag
    51361 cctgttgcca agctctttgt actcaatgaa aatcaaagag caaactagga aactagccac
    51421 aggttgctca aaacaccgtt ttgaggtagt agataagact gacgaagtca gctcaaaaca
    51481 ctgttttgag gttgcagata gaactgacga agtcagctca aaacactgtt ttgaggttgc
    51541 agatagaact gacaaagtca gtaacatcta tacggcaagg cgacgctgac gtggtttgaa
    51601 gagattttcg aagagtatta gtctattatt tcttctcagc gcgaagggct gacaagattt
    51661 gtgttcggat atcatccaca ccatttggag tatttggtaa aaagatagtt tgatttcctt
    51721 tagaggcaaa ggtattcaag gtatccaaat actggttggt caagaggata gacatgattt
    51781 gttcttctgt catgccaaca ttggcttcct tgagttcggt gatagactct gccaatccat
    51841 ccacaatcgc cttacgttgt tgggcaatcc ccacaccatg aaggcggtct ttttctgctt
    51901 ctgcttcagc tgcagtgaca attttaatct tgtcagcttc cgccaattct tgtgctgcga
    51961 cccgcttacg ttgcgccgca ttgatttcat tcatggattg cttaacttct gcatccggtt
    52021 cgaccttggt aatcaaggtt ttcacgataa tgtagccgta agtggtcatt tcttctgcta
    52081 cttggtgttg aacctcaagg gcaatctcat cttttttctc aaacaattca tccaaggtta
    52141 attttggaac agaagagcga agagcatctt cgatataaga tttaatctga gattctggac
    52201 gtatgagttt atagtaggca tctgtcacgc tctgctcgtt gacacggtac tgagtcgcta
    52261 cattcatcat aacgaacaca ttgtccttgg tcttagtctc aaccacaata tcactttgca
    52321 acaagcgcaa ctgaatccgt gctgcaatcg agtcaatccc aaaaggcaag cgaatatgaa
    52381 taccgctatt agcaaccttt tggtatttcc caaagcgttc aataatcgcc accgactgct
    52441 gacgaaccac ataaactgta ctcagtgtga ctatcaccaa taggagcaca caaacaatca
    52501 gaaaaatcat gaaaaatatt gccataatgg aacctccaca agtatttttc tagtattata
    52561 gcacatttaa agaaggctgt gccgttttta ctgcgatttt tcctgaaatg tcaataatta
    52621 gaggtgaatt gtcctattgt cgtctaatct cttgctaaaa taactcttta taaaaggcaa
    52681 tcgtttcttc taaggttggc ataaatggat ttcctggtgc gcaggcatca atcaaggcat
    52741 tcttagaaag gtattcaaag tcgaaatctt tttcttcaat accaagttca gtcaatttct
    52801 taggaatacc tactgtctca gaaagcttct caatctcagc aatcgcataa tcggcacatt
    52861 cttgatctga tttaccttct acatgaagtc ccaaggcttt ggcaacattg cggaaagctt
    52921 ctggtacacg tttagcattt tcacgctcta taactggtag caacatggca cagcaaacac
    52981 catgtggcaa attatatact gcaccgagtt ggtgagccat tgagtgaaca taaccaagac
    53041 cagcattatt aaagctcata ccaccaagga agatggcatt gaccatacct tcacgcgctt
    53101 caatatcatg tccattttct acagcacgag gaagatattc cttgataagc tcaatagcac
    53161 caatagacag tttcttggtt acatcataag caccaggtgt taccaaagct tcaacagcgt
    53221 gagtcagagc atccatacca gtagcagcag tcaaggcttg aggtttggaa agcatgagtt
    53281 ccgggtcatt gacagagata agagcaaggc tattcttgtc aaccattacc atcttaacct
    53341 tgcgttcttc atcagtaatc acatagttaa tagtgatttc tgcagaagtt cctgccgttg
    53401 tattgatagc cacaactggc aagccttttt tagcagactt atgaagccct tcataatcct
    53461 gtggtcttcc accatttgta gccatgatag aaatacaact agctgcatcc tgtggagaac
    53521 ccccaccaag actgatgata aaatcacatc catgttcttg caaagcagct accccatctg
    53581 tgacattctt acaagtaggg tttggctcta catcgctaaa gatgacatat tcgattcctt
    53641 ctgtatccag tggttttaaa accttaggta aaatgtcact gccttcgatg tacttatctg
    53701 tcaccaaaag tgccttttta tagccaagtt ccttgatata aggacccact tcatttacaa
    53761 cacctttacc aataaggttg actgccggaa cataaaatgt agccatataa ttttcctcct
    53821 gcgcctttgc gctatctatt taacatcatt atattacttt ttgtattcgt tttcaattat
    53881 ttgtgaattg tttaacaaat ctttttaaaa ggataggagg gacgtaagtt cacctcctat
    53941 ataaacaagt tttatttatg tagtggtccc aacaactgac atgcacgata gtctgctgat
    54001 tctagatctt ctgttccaaa taaggaccaa tttttaggtc taaagatatc ttcctcaggt
    54061 acattatgca tattgacagg aattctcaac atagaagcca aggtaatcaa gtctgctcca
    54121 atgtgtccat atgttatggc tccgtgatta gctccccaat tattcatgac gtcatagaca
    54181 gacttgaaag caccttttcc tgtcaaacgt ggagcaaacc aagtagttgg ccatcctgga
    54241 tctgtacgat tatctaaagt atggtgaaca tcttcaggaa gttcaagtgt ataaccttct
    54301 gcaatttgta gcactggacc aacccctttt agaagattga gacgtaccat tgttactggc
    54361 atatccccct tcgtcaagaa acgagttgag aatcctcctc cacggaagta ttcgcggttt
    54421 gctggtggga agtctgtatt ttcaagcata gcctgcactt cactttcttc caactcccag
    54481 aatggtttca taacaggttt gccatctcga gtagcttgac ctgtaccatc caatgtacaa
    54541 gaaccagagt tgattagatg taagaagcca gctgcagcac gaccctctaa agtatgtccc
    54601 gttacacgtt taacagcctc tgggctccaa taagtacgca catcagcaaa gatttgtgga
    54661 gtatttgtta atagataatt aaagagcata gacacaccat ttagtgaatc attctctgtc
    54721 gcaaatacaa atggttttcg aataccattc cagtcaaact gagtattgag gaaagtttcc
    54781 ataaaatctc catttggaaa atggtctgtc cactgacgtt gaccttggaa accagctact
    54841 aaagcatggt gaccaaccgc ttcttcctca aaaccaagtt cagcaagtct tgggttacca
    54901 accattaagt cacgtccaat catgaacatc ttaataacaa attcccattg tttttctttc
    54961 tcttctttag aaagaatcaa atcctcacga tttcggtcaa ccccttcttt gatatgttct
    55021 tttacccaaa ccatagcacg ttcgaactct tctgggtcat aaataccacg gtccatacgg
    55081 cgcgtgaact ccgtcatatc taccgattca tttcgcattc ctaagtattc ttggaagaaa
    55141 tctggattta caatagaacc gccaatcccc atcgaaacac tacccattga taggtaagca
    55201 gtgtctctca tcaagccagt tgcaagagct gcacgcgcat aacgtaaaag tttttctttg
    55261 acatcttctg gaatatctgt atcattagct tcctgaacat ctctaccata aatcccaaag
    55321 gctggaatcc ctttttgagc atgtgaagct agtacagctg caagatagac agctcctggg
    55381 cgttctgtcc cattaaatcc ccaaatagca tgaggaatat ctggagacat atccatagtt
    55441 tcactaccat aacaccagca tggtgtaact gtaattgttg cgcaaacatt tgatttttta
    55501 aacaactcat gggaagctgc agcctctgga acacgaccaa tggtagatgg agaaatcaca
    55561 cattccacag gttccccatc tggatatttc aatgtgcttg aaatcaaatc tgccacactt
    55621 ttagccatgt tcattgtttg tacttcaagt gattcgcgta caccttgacg acgaccatca
    55681 atagtcggac gaatcccaat acgtggatgt tgaatcatac tattttcctc ttatttttct
    55741 gtttctttca tactaccatc tccattatat ttacggtagc ctgggtgacg acctgtaacc
    55801 ttataatttt ctcgcattga gaatagacgt tctaaagtcg gacgagcaat ttcttgctcc
    55861 tcaatgccct ttgtagaaag taacattctt ccgtggaagg ttgtctttgc gactaattct
    55921 aaagtttcca tacggtagta tgctgtaatg acatcgcttc cgacagtcag agctccatga
    55981 ttttctaata gcatgacatc atgatcgggc agataaggtg taattgcttc tggcacttcc
    56041 attgtagacg gaactccaaa tggcgttata ggaattgccc ctaccacaat cgcgctctca
    56101 attagtgaat aagtatctaa aggaatgtgt gcaagagcaa atcctgttgc aatcggtgga
    56161 tgcgcgtgaa caactgaacg gacatcctca cgttcttcgt agcaccgaat gtgcatttta
    56221 atttcactag aaggacagta atcaccttct gcttctaaaa tctctccttt aagatttaac
    56281 ttcaccagct tttctggtgt aataaaactt ttgctgatac cagtaggtgt tgcaagaatg
    56341 gtatcctcat ctaatcgaac agatacattc ccatcgttag cagcaaccca accaagttgc
    56401 cacatcttat gacaaacatc acaaatctgt tcacgaatta atttttcatc ttgagacata
    56461 aactcactcc tttctaaaaa tgaagttcga attcaagatt tccgttactg ttaatggtaa
    56521 tagtaaccat atgatttttc tgatcaaaat tgagagatgg ctgatcatag gaattatttg
    56581 ttcctgataa tgaatgaata gtaggaagtt tatctatacc tcttaatact atctttgtaa
    56641 cccttttctc tccaaactga gtatctttga tataatgttc ttcaatccac ttaatcgcac
    56701 ctttcttggt caattgtggt agtttctttg cctgatttgc atcttgagca ttagaccata
    56761 gtgaatcttt atttgttcta aaattattta aattcacttt caatccatta cttattctct
    56821 caaaaatacc ataggtatga ggttcaaatt caacatccat ttctaaagaa ttaaatttta
    56881 atttcccagt ctgtttaaca ttctcattta ccttataatt atagacaaac catctattat
    56941 ctaatttctg agcaaagata tctccttcat aattcatagg atacagctta tttaagtatt
    57001 cttttctagc ctgagtagag ctaaattctg gagaagtgat ttccttaatc tgaatacggc
    57061 taccagaaac agactctttc aatttatctg tttttaaaac acctggaata gctggaataa
    57121 cattataacg accagtcatg tataatggag tttgttctct atcagtattt acgtttacaa
    57181 agaacttacc atttccttta tttgaatagt ctccatgtat gaatactttt gtatcctcaa
    57241 gtaccttttc tttggatggt gctggatgcg ctattacata tctaaaaaat tcttttatta
    57301 cttcgctaaa gagtaagctt tctttattat ttacaccata ggtataagct gggtgttcaa
    57361 aattataaac tacacctcca ttaaggtaaa cccctaaagc ttcttctcct agcatagact
    57421 ctggttcagt caaccattgt ctatctcctt gactttttcc gatattacca cttgcaaaca
    57481 gtttccattt acctgtctca taccacttcc aagtatccat caaaccaccc cattgataag
    57541 tatgatttga aagccaaagt cccttcatat aactttctgt agttgaatca tttccctcag
    57601 cagcaggtgt atttttgaac atgaaaataa ggttcttcca gtacttatca acagatttct
    57661 gaaatgctat cttaccgttt tttccaaatg ctttttctat tgcagaacca ttattttgtt
    57721 cagcccatat aaaatatcct ccatttttag ctgatacttt taagtaatct gccgccttat
    57781 tttcaatatc atttgcccaa atccaataat tctctgtact gaaaatacca tgcaaatttg
    57841 gatatttttg atacatttta tcaatccagc tggtacttaa ccaatgtgcc gaagtataat
    57901 aaggcatatt accagcagtg taaaccgtca gaataactgg aattggttca ttttttccag
    57961 tcttaggatt tacatatttc gctgcttctt ctaacatatg ttcataaaaa tctctagcag
    58021 ctccatctct tttaggaaga tcatctggat gtaactgtat aacagtatat ggttttaagt
    58081 catctggtat attctcccac ttacctgtta atgtatctcc tccccaaaaa gtatatttcc
    58141 cttggttaaa ctcttctccg ttagcatata aaggcatcat aagtaacgga tgttcattat
    58201 taatttcacg acgtttatca acttctgacc aatcattagg attcttaaat ttaccatttg
    58261 ccataaacaa ggctccacct aaaaccaatt cgtcagccca tgtatgtttc cctgaatatg
    58321 atttaagttc tattgtctgt gtatctttgg gaatttcaac atcaaccaga aatgccgatg
    58381 tatcatactt aattcctttt ggatattttg aatctgatga gtaaatgact ttaccatccg
    58441 caacaacttc aaatttttga atatctgcgt aatctgaatt taaatgattg gcactcctat
    58501 caattccgac ataggaaata aatcttgtaa cattagcacc cgaaacatca tattttatac
    58561 tagacgggtt acttgctaca gttcccaatc ccttattaaa ttcgacttcc ttaccgtcaa
    58621 ttagtaattt tattttatta ttagacccgt tattaccagg tgtaaacggt ttatctttct
    58681 gaactgtttt tgatttatcg tcatcaccat gagtagcatc aacccattct aaatcagaaa
    58741 gatatactcc tccattaatt cctttattaa gaagatctgg agttatagtt tgagtactaa
    58801 cagttttaat aagtttagca tcagcaaata caacttcatc accccatgta tgttctcctg
    58861 cgaatgattt taaggatatt tttttagcgt tttgtggaat tgtcacacta ataaattgtg
    58921 cctgggtatt atatctgaat ccttctggat tagttacact actagaatag acaacctttc
    58981 catctatttc tattttatcc actactgcgt ggtctgatct agaactatta gcactttgat
    59041 caattcctat ataagtttca aatttttcaa atccttgacc actaatatca tagctgatta
    59101 cagacgggga atctgcgact gtccctattc ctttatcaaa atacttaact ttattgtcag
    59161 aagtaagcaa tgaaatctta gtatgctctc ctttatttcc tgttgtaaat ggagcatctt
    59221 tttgtactgt ttttgtttta tctatatcac catgagttgc agaagaccaa tccatatctg
    59281 aaagatatgt catctcttta tcaatttctt tacctttagt aataagtttt tctaagttat
    59341 tccctgttac tctagcagtt tcagtactag ctctgttatt agaattactt tgaactacat
    59401 ctgcataaac caaattactt cctaaaaaac ttgttaaaac agccgtagct attaaaatct
    59461 gttttgctat ttttttactt tccattttta tttcctcaat atttacatac aacttcctca
    59521 ataacaaata attttgtaag atattctgga acacaaagtg ctaaattact taaacttact
    59581 tttattccag cattcattaa ttcatctcca taaaagaact catcaaatcc agagacggaa
    59641 tagcatttat ctttatctaa accactaaaa taaactcttg tataacctgg attcaactta
    59701 ctattcaatt gagcatacaa taaaatcgat tggcatttat cttttgaaac aacttgccaa
    59761 ctagcagaat cacaactaaa aggactgttt atcctataga aatccccata ttgaaacaat
    59821 gaacgatatt ttttataaaa ctgaatttgt tctctcactt gttctttttc ttctaccgac
    59881 aatctcgtaa catctaattc ataaccgaaa gaactaaaat aagctacatt tgtcctagtg
    59941 tccaaactcg tttgtcttcc actttgttca tttggagaaa tagaaacatg ggctgtcatc
    60001 attgatggag aatatccata agaagttcca tgctgaattt tcaatctttc tatcgggtcc
    60061 gtatcatcac tcgtccacgc ttgcggtgca taatacataa gtcctaaatc aaaacgtcca
    60121 ccacctgaag aacaagattc aaatagaact gaagggaact tagttattaa acgatctaat
    60181 aactgataaa gacctaagat atatcgatga ccaaattcca tctgctgttc agaatcaagt
    60241 tcaatactat aaatatctgt tatatgacga ttcatatccc atttgatata atccagattt
    60301 gttttgatta tgattttaga aatagaatca aaaagataat caacaacttc ctgtctcgtc
    60361 aaatccaaca catattgatt tcttcctact gacttctctc tgtctaacaa atggatagtc
    60421 caatcggcat gattcttgta caaatcacta tcaatagaaa tcatttcagg ctcaaaccac
    60481 aaaccaaatt gtaaacctat tttgtgaatt tcatctgcaa gaaatccaat accttcagga
    60541 agacgacttc tatctgttac ccaatcaccc agagaacttt tgtcatcttt cctatgacca
    60601 aaccaaccat catccagtac aaataattct atccctaaat ctttagcagc ctttgctaaa
    60661 tctaaaattt tttctgtact caagtcaaaa taaaatgttt cccaactatt gagtattata
    60721 ggacgactag cttgagaaaa attaggatta actaaatgat gtcgataaaa atctgatagt
    60781 tgttggctca tctgattcat cccttgatca gaatagatca caattgcttc tggtgtcaca
    60841 aaactttcgg caggatttaa taaaaaacga aattctactg gatttattcc taccgttact
    60901 ctagcggtgt caaaatggtc aacttcaatc atattttgaa aatttccaga atagataaag
    60961 ttaaaaccat aaacctcacc actatgctct gtagtttccc tccttgatag cataaagaaa
    61021 ggattttgct gaggacttga tgagtatctc aagctatcta ttgcttgaat acctggtcta
    61081 agcgaagttc tatataactg acgttccctc agccatgctc cagaaaattg aataaagtca
    61141 tattgactat caggtagatc tagctgtaag ctcattgctt tcaaaagagt caacttatta
    61201 ttgctattat ttaaaaattc cgtatttcta actaagacat tgtattccgg aaaaattgtg
    61261 taatttagtc taacagttaa atctaatatg gaatctgtta aaataatcgt taatgtttcc
    61321 gcacactgac caatatcatc aaatgttgaa ggtagagagt taagacgatt tttccctttt
    61381 tcaagttcaa aaccttgata ttttagtgtc gttatcctac taccattcat tccttgaact
    61441 tgaaaggctg gatgccgaaa atctcctttc ccatatgaag aatattcatt ttgtatcata
    61501 gactgttgaa tatcctcaaa ttcttcagaa aaagatactt caaatcctct tttttcatag
    61561 gccatcaatt ggttataatt ttccttgaca tgaatccttt tcccaaaatg tagatgttga
    61621 agttccccat tttctaaaat tctaaaaata taactactat ctttcattgc caaatgaaaa
    61681 acggtctcgt ccttattaat ataaatcgtc atctctacct cacaattttt tctttatttc
    61741 ttcagtatca cgatagagta cggtgccaat tctatctcat cttcttgaat agtaaaatct
    61801 ccaattactc tggtaaaatt ctctatcgaa agattctcta tttttatttt ttgtttaatc
    61861 tgagcaggat ttctcagaga gagaatttca gtagaagtct tctgattgtg acacttataa
    61921 ccataaattt caaatttttc aggacttcct cctatttttt tactatattt tagtgtttga
    61981 taattctcct ctatccattt gacggcacga gcattggctt tccagcgttc ttcatcaaac
    62041 atatcaaaag aatagtgaaa ctcccaaaaa gcattccctc ttgttgaaat aaataataga
    62101 taagcttcaa aatctggtat tgatgcaaac atttgatgat ccatgtacca ggtatttgca
    62161 ctgacagcat agattggttc atgattataa agcgaccaca taggtaactg tatctcacgt
    62221 ttttccaaaa attcttgata ctgactatct cggtaagtaa tcatacgatt gatatcatta
    62281 cctgcattct ctgtaaagcc tacatcttga gatatttgaa tccataaact attgacccac
    62341 tgtaaaaacc atggactagg atttacataa gaagtcaagt ttaaccaaca atcttttcct
    62401 cctctctcct ttcttagatc tatcaacagt tgaattaaga actcataaac cgctgtcatg
    62461 gtatacatac cgtgcggtcc actcttatca ggtttgtcag gttgaagtaa ccaaccatca
    62521 attttccaat agctgatatc gaattctttt tgatattcca acatcttttt cttcatttga
    62581 ttgagatagt taaaatcagc cacgtttaca tcatttgaaa tcaaattttt agatccaata
    62641 tttaactctg gatgtgcttc taaccaatca ctcataatga tttctgtccc attataacca
    62701 cctcggggac caatccacaa tcctaggctt gaaccaaatc catttacaag atgtttaata
    62761 tttctcaaac catttgggaa tttatgattg aattcccaaa ctgattgata gtttgtccaa
    62821 ccatcatcaa caacataagc atctaaatga actccatgat tttcaaatcc atctcgaatc
    62881 tcagaaaaac tttttagaat accttcctct gtaatatcgg tcatatggtc ataccaggaa
    62941 ttatactgtt tacggaaata actaggttga gctattcctt caacatattc aaaaaatgcc
    63001 tcttgaatct cttctttttt ataagagcat gctcccccaa taatacaaga ccacaaactc
    63061 ttttcttgat ttacaacagt tcccaagtaa tatcttgata catagtgtct accatctacc
    63121 ttgttttcag acattggaaa ttccattcct aagaataaag aattcgcata aacaggttgt
    63181 cccaattcta cataataacc ggaaaaattc gccatttcct taatacaatc ttgtcttttc
    63241 ggatagaaaa tattgtcttc tgtttcaaac tcaaaactct ctacctctac agatttaata
    63301 acctcagtag atgattctaa aactaattgc ttcgaaagaa catcatccct cgattcaaag
    63361 attaaacgta aacgaatgga aggacaaaca aaagaaacct gaattcgcgt atctccctct
    63421 tccctaacga ttgctgaaaa atgatttgaa gaaagtctta taccattctc caatgtaatg
    63481 gtaaattctt ctttcgaaac attttttatc attactcctg cccgtttgtt tacgatatca
    63541 gtagtataaa atcgaccatc tccccaaaag aaattacgtc ttacattttt attttcaatt
    63601 ttcatataaa ctactctctc aactcaattt tgattacgct atcaatcaag tctggtaatg
    63661 gataggtaaa atgtggaact tctccaaact gtgcaaaaca aattcctttg taggcattgg
    63721 tcgtccagct ttctgaaatt ttcacctcac ttccatcatg aagaaagctc attcttttta
    63781 cgttttcttt actaatacca agaagagcta aaggacctat aggttgttca aatacatgag
    63841 cataaaccgt atttccatta cgagtatagt atccccaatc tggttttggt aaattttcat
    63901 ctccactaca tccataaatt gcctcaccat ttcgagacat ccatcgatga aaattatcta
    63961 atattttctt acttgaatca ttaattcttc ccaaagcatc tgggcctaca ttaagaatca
    64021 tatttccgtt tttactaaca cattccacta actttcttat caaagtttga ctagacttat
    64081 atagataatc tgtaggatta taagcccaat tgttattcat agttagacaa agttcccaag
    64141 gaacaggttc acctttaaag tttcgaatac cttcgtgagg aacaatttgc tctggactaa
    64201 caaaatctcc agcgtaagag gtaatttcat ctgtaacgat acttccgaat ccttcacctg
    64261 atgtttctaa tctattatct acgataacgt ttggctgata atgacgaacc atgtctatta
    64321 attttgaagc tccccatttt tcacccacca tgtcttcata agaataatca aaccataata
    64381 tgtcaatctg accataacca gttacaattt ctttaacttg attgtgcaaa tactccaaat
    64441 aactgtcaaa gttaattttc tcatctcgat aggcttcatt tcctctcatt ggatgattta
    64501 gatcagcata tttagggaaa tcaggatggt gccagtcaat caaactaaaa tataagccta
    64561 cttttaaacc ttcagctcga acagcatcta caaattcttt aactaaatct ctacctgcag
    64621 gtgtatttgt tgctttataa tctgtaaatt ttgaatcaaa caaacaaaac ccatcatgat
    64681 gtttagccgt taaaaccata tacttcatcc ctgcagcttt tgcttgttta gcccattctc
    64741 tagggttata ttccttagga tcaaaagctc gaaaatatgg ttcataatct tcaatagata
    64801 atttctgatg actacgaatc cattcccctt ttcctggaat agaatataac ccccaatgaa
    64861 tgaacatccc aaatcttgct tctctaaacc actgagttct actattgata gtttcaagtg
    64921 tatgtttcat ccttttactg ctcctcctcc taaagcttca atgaagtatt tacttgtaaa
    64981 tgcgaataga atgattggtg gtaatacgat tacaacaata gctgaaaata gaccattata
    65041 attagtatta aaacttgtag taaattgacc tagtaatgct ggtactgtta attcattttt
    65101 atcaatcacc aacatagatg cccaataata ttcattccag ttgttaataa aggcaagtac
    65161 tgctgctgtt aaaattcctg gtctagcaat tggcaacatc actttccaaa aagtttgagc
    65221 atatgtcgca ccatcaatct ctgctgcctc ctccaattct tttggaataa tttcaaaata
    65281 gttctttata ataaagaaac tcatagcaat tccactacaa gagtagacca gaattagagc
    65341 aactggggta ttataaatcc ccaactcatt tactaatcta taaactggaa aagtcatagc
    65401 tgttgctgga ataaatagag tagaatacag catagaagtc accaacttct tccctctaaa
    65461 ttccatccta gcaataacat atgaagacat ggagatcata acaatgctaa taataactga
    65521 tatagacact actttaaagc tattccaaaa gtaagtgaaa acatgaagtt ttgtaaaaac
    65581 atttatataa ccttcaagag taaagtcagt cggtaaacta atacctggat ttttcatagg
    65641 atctgctttt aatgatgata aaaaaatcca cgcaataggg aaaatagaaa ttaaaatggt
    65701 aaggagcata taaccatata taagaacttt gcctttttta ctaataccat ttatatgtgt
    65761 attcataatc atttcccacc tttcagtctt tttctttctc tgaataaaat attaatacaa
    65821 acgataatca acattccacc taagatttgt ataactccaa ttgtatttgc acgagcatac
    65881 tgagttcgtg agctagccac tgctaattct cgaataacaa aactgatact ttttgttcct
    65941 gcagcaccat ttgtcaaaaa gaatacttcg ttatagagca aaaaccctga agttgctgcc
    66001 ataattgaaa cagttttaat tgtcccctta atcatcggaa tcgtaatata ccactctttc
    66061 ctccaaccag taatattgtc taaaatagca gcttcttgaa cttcttctgg aatagcaaaa
    66121 atttgcccaa gaatcataat ggttgatgct cctgcaaaga agatataagc gccagtcata
    66181 gctactatat ttaatcctgg agtcaacagt actgaatctt taaacgatgg attaaataga
    66241 tgaataattt ggttaacaac accatagttt ggattataga tttgaagaaa aatcaagccc
    66301 atagcagcac tagaaatgat acttggtaca atataaagat tcctagatat cttccagcct
    66361 tttaatttct tagataatgt aattgcaaca gatacagcta aaggaacttg aataataaca
    66421 ccaattacag cccaacgaac agaattaatt agagcttctg taaaaaatgg gtattcttta
    66481 aaaacatacc tataattttc aaataattta tcaaatccaa gaaactcagg ggtgtttaaa
    66541 tttgtataat cccatttagc aaatgaagtt aaaaagattg ttactacaga ataaaaataa
    66601 aatagaaaga aacaaatcaa cgttggcaaa agaaataaaa agataaatcg tcttttttga
    66661 ttcttcctat tttgtaggct cataattttt tgtgccataa acaaactcct ttttttcaac
    66721 tatataagta aaatcaagct cagttggcag tgccaactga gcttcgtttt cactccctaa
    66781 aacaattaac caatcaatga tttcaacaca tcttgagtag attttacttt ttgatcaaca
    66841 tctacatttt cagcagcact ttctgtcaat gcattgataa tagctgtgtg tacatcgcca
    66901 ccccaaacat cacttacagt tggaacaact gcttttgcat tcttaacttg agtgattgct
    66961 tgtcctaaaa ttttagtagt agcttctgaa ctcttttctg aaagttcttt tacatttaca
    67021 ttttcattag aaggatttgc tcctactttt tcaaaaatta ctttttgtac atcatcgcta
    67081 gtcatatatt tcaaaaactc aagagctagt ttttgtttag cttcagacat cttacttgag
    67141 atagtgatac cacctccaga agaactaatt gctacacctg caggatagat tccaggtgca
    67201 agacttgggt tcttagacat ctcaccagaa gcccacacac cattaaagaa tactgcagat
    67261 ttaccttctt ggaaatcttt ggaataagca ttggcatcgc caccagcatt cttagaacca
    67321 ttagcttgaa tttctttcat aaccattttc aaagcatctg caaattcttt agattcaatt
    67381 ccttcttttg ttaatggttt atctaataat ttacgtccat tttctgtggt tcctaatact
    67441 gtattaaaca agcgaataga tggttctcca gcaccaaatg catacactcc atcttgtttt
    67501 ctaatgcttg ccattgcctg agtgaaatca tcccaagtat tccactgatc aggtgtctta
    67561 gcacccgctt ttgcaaatat gtccttgttg taccacaaac ccattgtaaa taactgttcg
    67621 tgaactgtat aaatttttcc atctttttgg ttttgcttat agttcaaacc aacatttttt
    67681 tcaagcttat ttgaatcgat atatggtttc aaatctaaaa caagtttttg ttcaatcgca
    67741 gctaatgata ctgcattacc tgctaggtca atcacatcag gaaattcacc actagcaacc
    67801 ttgttattca ttatatcctt caaatcacca tttacaggag ttggtttaaa ttctacacca
    67861 ctatctttat gttcttctgc aaatttatca tataaatctc gcatagtctt cgctacaggc
    67921 cattcatctt cactatgatg atacccatga taaaattcta atacttcttt accagaagaa
    67981 cttccaccgc ttgcatcctt agatgttcca caagctgcta aaccaaaggt agctactaac
    68041 ccgataacag cgcatttcaa aagacttttt ttgttcatga caaaacctcc gtttttttta
    68101 tttttgttta tgatagctga ggataataat attttgtatc agcaatattt gtcataatat
    68161 cctttaactc tgtatcctcg tttattttac cttgactcaa tagctgcaca acaatattcc
    68221 ccacagctgt accctcagtc gaacctgtaa gaacctcttt accagttcta tcagcaatca
    68281 tttggttaaa gtaactggct ctagcacctc ctccaatcac atatatcctc ttataaacct
    68341 tatgagttag ttcttctaat aactctatcg ctttcctata cgtttcagct aggctttcat
    68401 aaacaatctt aaatagttgt ccatctgtcc actctctagt ttcatgatga taagctagat
    68461 attctgtcaa agtcttgtgc atatcagatt ctgttgcaaa ttcagttgat tcagtatcaa
    68521 tcagaggaag attttctttt tctttctcca ccattgtcct aatatcatca aaagaatagg
    68581 ctttccctct tcgttcaaat gaacgtctta gttcctctat gatccacaac cctgtacaat
    68641 tcttcagaaa tgtaatctct ccatctttac cgacttcatt tgtaaatcca taactgaagg
    68701 attcggtagt aagaatcggt gaagtaagtt ccactccaac caaagaccaa gtacctgatg
    68761 aaataaataa actaccttct gtcttaggta ctgagacaat cgcacttgct gtatcatgac
    68821 tacaaacatt cacaacagga atatcgccta aaccatactc cttttttatc cttccaagaa
    68881 catttccctc tgaaacaatt tcaggaagta aagatgaatc caattcaaat agttttaaga
    68941 tattctgatt ccaattttga ctcctaggat caaataattg agttgttgaa gcaatgcttt
    69001 tttctgtagc aaacttacct gtcaagagat aattaaacaa atctggcatt aaaagaatct
    69061 tattggtctt atagaaagag tcaggagatt cttgacgtgc cttaaagagt tgaaacaagg
    69121 tatttatctc cataatctga tttcctgtct ctgaatacag tttttctaat tcagtcattt
    69181 cagatatttc ctttaacact ccctttgttc tttcatcacg ataatgaaca ggttgtgata
    69241 acagcttacc ttcattatca atcagtccaa aatcaactcc ccatgtgtca ataccgatag
    69301 ataaaatctt gtaactagta ttagccaagc ggatactttc aagaatttta gctagtagaa
    69361 agtcaatatc ccaagataaa tgccctttta ctctaatagg tagattagaa aagcgattta
    69421 tttcttccat tactagttta ttttcagaaa ggtaaccaac gattgctctt ccagaagtcg
    69481 cacctaaatc tattgctaaa accgcttcca tttttcttct ctcttcgtcc ttgattaact
    69541 ttattataat ccccacattt tattttttca atatgtgaac gcttacttga ataatgttca
    69601 aatgttaacc caatattcat aaaaataatt caaattcctc caatttgtgc tataatatag
    69661 ttgaaatgat aaattaggag gagcttatga taaaagatga acgtgtactt gaattgattg
    69721 aaattattaa aaagaaaaaa agaattgccg taaaagagct ggcagaaatc actttctcca
    69781 gcacaagtac cttacgtcgt gatttaattt tcttagaaaa tcaaggtctt atcaaaagaa
    69841 agcacggata cgtgaccctg tcctctatga acacaattga actttctcat caaatacggg
    69901 aaggagaaag tactaggcaa aaaagactaa tcgctagtct cgctaaagac tttattcggt
    69961 ctggtatgtg tgtttatctg gattccagta ctactgtcta cgaactttgt ccctatcttt
    70021 ctgaacttga taatttgatt atttttacaa atggtttaca tactgcacaa accctatctg
    70081 aaactgttaa agatagctcc aaaatcttta tcacatctgg cgaggtcaaa catcaatcct
    70141 gttccgtggt caattacgat aaggaaaatt ctttattaga tcattttaat atcgatttag
    70201 cattttgttc agcaagaggt attgatgacc aatatgttta tgaagcttct ctcagccaag
    70261 ctatttcaaa aaagaatatt attgacaaag cccatgaaac tatcttactg attgatagtt
    70321 ctaaatttta caagactgga ttttttaaaa ttaatcccct ctccaaatac acaaccttta
    70381 tttctgacac cgtgccagac caaaaattat tagacgcagt cgaattattt gatggagaat
    70441 gggtttctga tattcaatga aaatcaaata ggaagctagt ctcagcttgc tcaaagtaca
    70501 gatttgaaaa ctgatgaagt caagtccccc atggacacgg aaagacgaag ctgacatgat
    70561 gtgaagagat tttcgaagag tatcgttctg tctgctgact gatttacaaa tattcaccac
    70621 atgacattat tttcttagca accctaaaaa cagaggctgg acaaaaactc aatttcagga
    70681 gaaaatggag taaaccttcc cacaataaaa cgcatagtat caagtttttg cacacctgat
    70741 attatgcgtt tttctgattt taaagacttt gtcgcctaga ccctatattt caagaattaa
    70801 gtgaccttga tgatctaaat gtattgtggt atactatttt tgtcatcggt taccgattac
    70861 gttcctatgg gttcgtgaga ggaggtgaaa ctaatgagcc ttatcataga gctcgctctt
    70921 actattatag cggatgttat agctggaatt atcttgtatt tcgtctgcag atggctagat
    70981 agtaaggagt agaccgactg actagcctat aaacacccat taaatcgcta agatacgtca
    71041 aaaaagccct taactacggc catagttagg ggctttggtg ttctaatgaa ccttatcaat
    71101 taactacatt ttagcatata atctacaata gttcaagcat taagtgaggt tgatgatcta
    71161 aatttagtgt ggtataatac ttttgtcatc ggttaccgat tacgttccta tgggttcgtg
    71221 agaggaggtg aaactaatga gccttatacc agagcttgct cttactatta tagcagatgt
    71281 tatagctgga attatcttgt atttcgtctg caaatggcta gatggtaaga agtagaccga
    71341 ctgactagcc tataaacacc cgttaaatcg ctaagatacg tcaaaaaagc ccttaactat
    71401 ggcactagtt aggggctttg gtgttctaat gaaccttata cactaactac attctagcat
    71461 ataagtccta atatttcaag agttttattt atttttttaa agttccttag ttctgaaagg
    71521 tctataatga agttagccat ctagtatcaa aaaaccgact agctcttatg aactagtcga
    71581 tttctcatca atgcgccaac atttcttggg cgatttcttg gccagatagg ttatctgggt
    71641 agtaggttgg ccagttgtcc atttcttcaa agagggcttc ttggcttgtg cctccaaaaa
    71701 agatatggaa atgttctgcc ttaactgggg cgatattgtg gtcactaaac tgaacatact
    71761 tgaattgtcc agcgtcagca tctgtggctt caaagaggaa acgcacgcca cgattgcctt
    71821 tcttgtaagt caaaattttc ttaccgacat acttgtaagt gtatttcttg ctttgtccac
    71881 cttgaacaaa ttccatagta ttatcagtaa tgttaatctt agtcacatct gtatgatagc
    71941 cttttgtata gtaagccttg tactcagcct gggtcatctt accagtcaac ttagccttgt
    72001 agtcaaagac ttggtcaaac gtgccgtctt caaggaaagg ataaactgat tgccagttac
    72061 ctgcatagtc actcaaggtg cggtccttga cagctgcatc ctcgaagtaa ccattttgga
    72121 ctgtcttggt atcctctgcc ttttcaggtt cgattgctgg gccttcttgg tctgttgttt
    72181 gtttcaaagc cttgaggttt ttctccatca cggaaatgta gttttctcca gccttggtgt
    72241 cctcttctgt cagactttct aaaggattga ggacatcagt tttgacacct gcttcttttg
    72301 aaagtgtgtt agcaagggct tgtgaggcat tttcttcaaa atagatatag gcgattttat
    72361 ttttcttgac atactctgtc aattctgcca agcgagcagc tgatggctct gcatctggag
    72421 aaagtcctga gattgcgact tgtttgagtc catagtccaa ggcaagatag ttaaaggctg
    72481 cgtgttgagt cacaaagctc ttttgttttg cttgagacaa gccttctgcg taagccttat
    72541 ccaaggcttg caatttttcg atataggcag ctgcattctt ctcaaaggtc tcttttttat
    72601 caggataatc tgctgacaag ctgtcacgaa tgtgctctac tagtttaatg gcacgaactg
    72661 gtgataacca aacatggggg tcaaactcat ggtgatgacc ttcttctcca tggtcatggt
    72721 ctccctcttc ttcctcgcca cctggcaaga gcaacatatc gcctgtcgcc ttgatggttt
    72781 tcactttttt cttatccaag gtatctagca atttaggtac ccatgtttcc atgttttcat
    72841 tttcataaac gaaggtatct gcatcttgga ttttggcaac tgccttggca gatggttcgt
    72901 attcatgagg ttctgtccca gcaccgatta ggagttctac attagccgta tctcctgcga
    72961 cttgcttggt aaattcatag acagggtaaa aggttgtcac gatattgagt ttaccatctg
    73021 cctgtttttg attggaacaa gccactaaaa acaaggcaca tagactggct agtaataagc
    73081 taattttttt cacgttcgtc tcctatttga taaaacgtct tactaaactg attagtataa
    73141 agacagttac aaaaataatg gtaatacttg cacttgcagg tgtttctgca tagtaggaaa
    73201 tgtaaagtcc tgctaccatt cccaaaaagc caatcgcact ggcaagcagc ataaccgatt
    73261 taaagttttt ccccagacgc agggcaatac tagctggcaa gaccataatg gtcgatacca
    73321 gaagagctcc tgctgcagga atcataaggg caatagccac ccctgtcacc atgttaaaaa
    73381 gaatggacat ggtacgaact ggcaagccat ccacaaaggc cgtatcttcg tcaaaagtta
    73441 agatatacat aggacgaaga aagagaaagg tcaaaatcaa aacaaccacc gcaatgacaa
    73501 agagggaaat gacctgttct tcactgatag tcacgatcga accaaagaga tattggtcca
    73561 aactcattga actcgagctt ttacccttgc tcatgacaat cagagaaaca gccagacctg
    73621 ttgacatgag gatagctgtc ccgatttcca taaagctctt gtaaaccgta cggagatact
    73681 ccagaaagac cgccgcaatc aagacaatgg caatagtaga aacagttgga gaaatcccca
    73741 aaaccagacc aaaggctaca cctgaaagtg agacgtggct aagggtatca ctcatcaaac
    73801 tctgacgacg caagatgagg aaggttccca ataccggtga gaaaagactc atagcaataa
    73861 ccgccaaaaa ggcgcgctgt ataaagtcgt aagataataa actaagcatg gcccacctcc
    73921 tggccattct catgaacatt gaaacaacgc catggcgagt cttggttacg gactagatga
    73981 atattgcgat ccgcataatc cttaacttct tcagggtcat gggtaatcat caaaacagcc
    74041 ttgccatgat gatgggcgct gtggtgcatg agttcgtaaa attcattttt acttcctgca
    74101 tccatccccg ttgtcggctc gtctaggata aacacatcag ggtcagaagc aaacatacgc
    74161 gcaatcaccg ctcgctgctt ttgtccccca gatagagaac ccaagcgttt gtctcgatgt
    74221 tcccacatgc caactgagtc cagactggcc ttgatatgct cctcatcatg agcattcaaa
    74281 cgacggaacc agccttttct cggatagcga cccgacttga caaattcata gaccgtactt
    74341 ggaaaaccag cattaaaact ggcaatttgt tgaggaagat aggctattct caatttctta
    74401 ccttgcgtat ttgtctttga aatagccacc tttccaatgc gtggttgcag aattccaaga
    74461 ctagccttga tgagcgtcgt cttagccgct ccattttccc cagtcaaggt aacaaattcc
    74521 ccactatcaa cacaataatt gatatgttca agaacaggct ccttatcata atagaaggac
    74581 aaatcctcta ccgtaatata tctcattatt tgatttctcc tactaaagca gtcaaaaacc
    74641 gctgaatcac tttttgttca tttggagtaa actgagtcgc cacttgttca taggttaaaa
    74701 gtgtatgctc atggtgatgg tggtgctcct cagcgattgg acgagccaag tcagtcaact
    74761 gataaaaaat cacacgcgca tctttagaat ctttagatgt ttccaacatc ccttccttga
    74821 ccaaagactt aatggccttg gtaactgccg cctgactgac attgagacga cgggccaatt
    74881 ctgaatttgt taaagattcc tctgacaaga gcataaggat atgctcctga gtattggtca
    74941 gggccacctc gctagtgcaa tgacctatta ggatttcatg ctgattttcc gcctgcaaaa
    75001 tcacctcatt caaaaaagca ttgatatcct ttgctagctg tctcatatct gactcctttc
    75061 cttttagact tctctttttt aagagaaaaa tactattctt tgacattttg tttaccagtt
    75121 aattatatca caagcaaaaa aagagtcaag aaaaaacgtg aaaactagtt tcattcttga
    75181 actcttctat attatattat ctattgaaat tctttgacat ctccatcata agtcgcccaa
    75241 tctttgctga aaaagcgctc attcagatgg taagtcggag ctggtgtggg attggatagg
    75301 aaaggatcaa ctgccttgtc aaaagccaac caacccaacc aaccaaggtg aatggtgtcc
    75361 ttcataaaga aaggctcccc gccgtcctta gaaaaatctg ctatattggt aaaaccttga
    75421 ctttctaact ggtagcgaat cttctgcacc gtttgttggt acatatcctc tcgtagacca
    75481 gcatagtcca tccatttttt attaacaggt ggaatgataa aaatcgggtt taccttagat
    75541 ttagaaaact gtgttaaaac caactgcaag tcattatact ctggcgactt gagataggta
    75601 aagcttttct gagaatcctt taatttcttc aaatccttct tgatctgctc attatagaaa
    75661 taattttcca ttcccatctc attattggaa gtattttttt cagcatctgc tttgacaaca
    75721 tcttctattg cttgataaga aaactggtct ggcaagattt ttaaatactt agctacatgc
    75781 ttatcgtagt taacatagcc tctaaccgaa aactgaccaa aaaaggaggc ttggcgttca
    75841 ttaaaacgag ccaataattc aatcatttca ttgtctgctg tcgacaattc tcctttactt
    75901 gccaacttct gaaccaggtc cttcatagct acgtttggga actgttgcag taagcgagtc
    75961 gctgcatatt gactagcctg atccccagat tgatgtttca gaaaactagt caactggtct
    76021 ccattaaaat actgctggaa ggctgctgga tcatagccat ttttactgaa ccactgaggt
    76081 gagataacat acacaacttg tttattctcc agctgtggta acatctgttg cattccaaaa
    76141 tattggttaa gcgatgcagc tcccccctgt cctaaaagat aaggacggta ggaacgattg
    76201 tatttctcag ctaataccgc aggatgagca ccgtcaaaac gaagccattc actagagcca
    76261 aagaagggaa caaaacgcac atttggatca gatagtgctc tgactttttg acttcgctcc
    76321 ttaaaactat cgatagtagt agccactgct gaacgctttt cagctcctag attatgatgc
    76381 atctcagtag gataaaagaa aatgagcaga aaaaccaaca aaccagcgat caagaccggt
    76441 ccgaagatca tccataagcg tttaagcatt ttgtagctcc acaataccag ctatgatttt
    76501 attagctgta ttccagtcgt cacgaccaaa ctctgttaca gggacacgaa tgtcaaaacg
    76561 gttctcaatc tccacaatca actcaaccgt tcccatacta tccaagacac ctgcatcaaa
    76621 aagatcttca tccatcatgt cagaaacatc ttccataaac aactcatcaa taatttcaat
    76681 aacttctgat ttgatatcca tattttattt ccttttattt tttaaaccat agattattca
    76741 agaatccaga aaagattaag aatgacaaca tgacaacatg gaaagtgaca accatgccaa
    76801 gcaactgaat ccagcgattc tcaggtaggg cagccttccc tgcttttttc cgttccttat
    76861 tgagcgtttt tttcttgcga acccaggcat cattgatgac caaacctagt ccatgaaaga
    76921 gtccataggc gatatagtac caggtcacgc catgccaaaa tcccataatc agcatattta
    76981 caatgtaggc catgcttgag gttacattac gatttttaaa gactttcttt ctggttaaca
    77041 ccatcaccat tcgcataaag acaaagtcac ggaaccagaa ggacagactc atatgccagc
    77101 gattccaaaa ctcctttaaa tcccttgata aaaagggctt gttaaagttg atagggctac
    77161 ggattcccat caagtttgag atggccaaag caaacataga ataacctgca aagtcaaaga
    77221 agagctccag accaaaagta tacataactg ccaaggcata gagattaaag aagccacctg
    77281 actgcaaggc taaattcttc agaggaggta gtaaggtctc tcctaaaaca tgagctagga
    77341 taaacttata caaaaagccc cgcatgatat agcggacaga ttcatccagc atatccatca
    77401 actcatctcg ctcaggaatg gcctgataat tttcattaaa tcgcttaaag cgatcgattg
    77461 gaccactcga gaaagttggc atgaagagaa ggaaacggag gaattcccag agggtaaaat
    77521 ccttaatcac tccatctctc agctcgatga taatcccaac cgaacgaaag gtcaggtaag
    77581 aaattcccaa gaacccaagc aaagactgcg ttccattgat agctggttgc accttgacaa
    77641 agataatcgg aagtagggac agaaaactaa ctaagtagaa gacccacttg ccatccttgc
    77701 tttttcgata atgcttgtag aaaagcagga gcaatatttc ccagcaaagg taaataccca
    77761 aggcagctag ttgattggtc tttccaccca ccaacatggt gacaataaag aagagactta
    77821 ccaacacttc ataccaggca aagcgtttct tgaaaaagag acctataaag atgggcaagg
    77881 ttgcagcaat cacataaaca aaatactgag gattgccata tggctctaaa tgaggaagct
    77941 gttgaaaaaa ctccatcatc tcttattcac ctcgttaatc aatcctttga tgtcaatctt
    78001 tccatttgga gtcagtggca aactgtctcg gtaaaggaat ttagatggta tcatgtagga
    78061 catcatgatg tctgtcaggt cttccttgat ggccttggta atatcgatat ctcgctcaaa
    78121 ctgctcacga acactgtctt ttaagatgac ataagccaat agattttgta ccttgtggtc
    78181 cttgttatag cgcggtactg cgacagcaga ttcgataaag cgagacttgt tgaggttttg
    78241 agagacatct tctaactcaa tgcggtaacc gttaaactta atctggaagt ccatgcgtcc
    78301 gccgtagaga agcaagccct catctgtcat ggttcccaca tcgcctgtgt gataggctgg
    78361 cagatcttca aactcaaaga aggcttctgc tgttttttca ggattgttca tataaccttt
    78421 tgaaacagct ggcccagaaa caatgatttc tccctgctca ccatttggca gtttatttcc
    78481 ttcctcgtca atgataaagg ttggagaatc agccttggta tagccgattg gtaggcgttt
    78541 gagagtcgct aacatctcgt ctgtcacggc aactgctgac agagctactg tcgcttctgt
    78601 tgggccgtaa gcattgatga tacgggcatt tgggaaacgc tcgcgcagtt tttgagctgt
    78661 tttgaccgtc aattcttcac catcaaagta gaaatgcgtg attccaggca ttttctcact
    78721 gttgaagtat tcagacaaca tggccatatc tgcaaaggat ggtgttgatg tccagatagc
    78781 gattggcaat gaaaagatag ccgcaaagag ttgcttaaag tcctgagtga tgactgaagg
    78841 aagagtgaaa agcgtaccac caagtgccaa ggtcggtgcc caatacatga cagacaagtc
    78901 aaaagaataa ggtggctgtg ccagcatttg cggacgactc ggtgtcgcaa attccttatc
    78961 cgtaatcatc cagtttgtaa agctgaggag attatcatgt gaaatctgca ctcccttagg
    79021 ctgaccagtc gtaccagaag taaagataat gtagtaatta tcatctccct tgactggatg
    79081 cgtgatttca tagttgttcc cttgggcaaa ggcttcttga acctgagcta gatttatcat
    79141 tggtgtagaa acctgctcca agggaaaggc tgaaatggca ataatcaagc ttggctctgc
    79201 tacttctaaa atagctgaaa ctcgctccaa ggccgaatgg ctatcaattg gaatgtaggc
    79261 atgacctgac ttagtcagcg ctacaaaggt tgccaacatt tcatattctt ggccaccaaa
    79321 aacaaccaca ggagacttct caggcaagcc tagttggtca atgactgcag ccaaactatc
    79381 cgaatcagac tttaaatcgc cataagtgtg ttcctgcccc aaaacattat agacaggata
    79441 gctaggctgt gtctgagcaa aatgctcaat ggtttcaatc atatctgcta ttggtttatt
    79501 tgacacaata gggattctcc ttcaagttaa aattcattat agataaagct tccttgaccc
    79561 tgaccaagat agctaaagaa gtaaagcagc cctagaaaga taagaaaata caaggctgtc
    79621 cgaccaagaa agaggtacaa ttcttttctc tgtttcatca agaaaaacca ttcatttctg
    79681 taatttttcg ctaaaattcg ctaaaataag agtgattctt actagcttat ttttctacca
    79741 ttgtaccact ttatatagta tcttttcaat tgtttaccgt atgtttccaa tagatttcag
    79801 cttattttaa ggattatgcg gtttttctat gtatattttc aaatagagtg atcctgcttc
    79861 aaaactccat ttcaggagac aatgaagtaa atcttcccat aataaaacac acaatatcaa
    79921 gttttttcaa cacctgatac tatgcgcttt tctgattttt aaagactttt taaccactct
    79981 ctcatttaaa ataatctcgt ctgatataaa ttaaaatagc ttctatcatc agacaaatgg
    80041 ctgatagcca aaaactgatg ctaataccaa aactctcagt aatatagctc attagcaaaa
    80101 caaatactga aaatgctaat gtagaaatca cttcaagaac ggaatagaca ttaactaaat
    80161 gattttcctc tactgtttcc tgaagaaata cactttcagg aacttctttt agttgcgata
    80221 acataccaac taaagctgaa aataataaaa acatctgtgc gtttggaaaa tatagaatag
    80281 tcagtgtcac tattgccata gctacaagag gaaaaagaat actttcccat ttagcagcaa
    80341 ggaacttttc agatagccta aaagcaatta agccactaat tataatacca atagagtatg
    80401 ctgtattaga atatccccag taactttccg ttttatttaa taactccgtt acaaaaacaa
    80461 gtataatgga agaaacccaa atcgtatttg aaaaaatttc caataaattt gctgatacaa
    80521 aaagtcttaa tctaggattt ctagcaacta acttccaacc tttgagcaaa atttcaagat
    80581 tagtttctga ctctaacacc tccacttcag cgttaggaag aaataacatc agaaagctag
    80641 aaatgatata caagactaaa atgataaacg tggtaggtaa cagaccaatt gttgcaaaca
    80701 agagtccacc taatccccaa cctatcaatt gaacagcttc accagtcatt gataaggctg
    80761 aattagcctt acccaaatcg gtcgcatagc gtggcacaat agcataggaa acgggtgctg
    80821 caaaaccatc tagtatggaa attgcaacaa caaatagata ggtcaccaaa ggcgctacgg
    80881 attgcattac ggtaaacatt cctaccagta tcgccaataa tatagtcttt ccaaattgag
    80941 ataaagataa aaccctattt agcgctaacc ttttagtaac caacggaact aaaagactcg
    81001 caacaaaaga ggatattcct attaagatag gaactagtga tgtggcaatt actgattttg
    81061 aaataatgta tatgttagca atgattgtta ctctaaagaa aatatctgct aaatttgcaa
    81121 ataattgaga gactaacaac ttgacaaatg aattagacat gtagcgctcc ccctttagtt
    81181 acaaactttg gaattaaatt tgatttttaa tattttagca taaaatagca gaaaacaaaa
    81241 gtgaggtttt ttacatgaaa aaacaaaaac tattgccttt attattccta attttaggag
    81301 gaattatgat tatcgttgtt ggctagtact aagaagttag ttagttagta gaataattac
    81361 atcttcaatc gaaaaagaga ctggaaaaag tcttaaaaat cagaaaaacg ctcaaatcct
    81421 ttggcgctct aagcttttct aatgatagat ttagatagtc aaaaaaatat ctgaaaagtt
    81481 cccaggatcg tcgtctcagc atcaaaaata cgtgaaattt gcataattaa aataaatttc
    81541 aggggagt
//
LOCUS       DAVHSL010000002        75017 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000002 DAVHSL010000000
VERSION     DAVHSL010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.002"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(52..1410)
                     /locus_tag="VVR39_000071"
     CDS             complement(52..1410)
                     /locus_tag="VVR39_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6029635.1"
                     /translation="MGKQDMKTQLLTKSPKDLLFQLAIPGIIGMVVIGLYPFMDGIFA
                     GWIIGDYAMSAISISMSLTIINGGISALIGVGSASILSRAIGKGDKETTDKIFGNFCY
                     WVILFSIVITVLGLVFAPNFLDLVGAKGNIKELGVRYLRVVFFGSIFVNFAQAGNMTM
                     RGEGALKQSMMIMGVGALLNIILDPIFMKLMGEYAIEGAAIATVISQIVQAILTFHYF
                     SKKSAFVGIHKIQKSKAIYSEMFSIGSSAMMMQILFAVQQTFLFKQAFAYGGDNWGIL
                     MSATMRLYMFSFIPLWGMSQGLQPVIGANFGAKQYQRVKDTMKIFMYGATILAAISWI
                     PSMFFSEKLLSLFNVRSEIIEAGVMNFKLFYSTFILYGIMIMTLTFFQSIGDGKKASM
                     IVMLRQLILFIPAILLLPKVFGGLAVWWAEPIVDFSMILLGLFLMLSRLRKIGKEEAI
                     NC"
     gene            complement(1446..3179)
                     /locus_tag="VVR39_000072"
     CDS             complement(1446..3179)
                     /locus_tag="VVR39_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029636.1"
                     /translation="MLSALKKILDFSGDEKKNIYHSIWVSFLFAIFHMLQISAIYFIV
                     KAVSEKDMSMTPAWIALILLVVSIVGRSIANYYSQLQQCHASYFMVANKRISIGEMFK
                     KIPMGFFNGNNGGEVVGISTTVLEDVENTAAMVMVNTLSGFINTIIFTLMILIFEWRI
                     GFIVTVGSLLYLVILSKMEKKSREVLPKRQMASAKLVDTVLEQIGGMSVIKSFNLTGK
                     GDEKVRGAIENTRKTNLDCEKLFTPYTIVQNILLDLFSILIIGAGIFFYQRGELSFLN
                     TVMTIIISFLAFSQIKLAGSATTALRVVSGSIEQTKKLEEFPQMDIEGKDIKPANFNI
                     SFENVEFAYSGKKILDDISVDIPQNQMTAIVGPSGAGKTTFCNLIARFWDIDNGKISI
                     GGHNIKEYSLESLMKQISMVFQNVYLFQDTIENNIKFAKPNATHEEVVDAAKKACCHD
                     FIMNLPEQYQTVIGEGGASLSGGEKQRISIARAMIKNAPIIIFDEATANVDPENEDKL
                     QLAMEELTRNKTVIMIAHRLKTIKNANQILVLANGKIMQKGTHEELIQTDGIYRNFVE
                     ARQVATKWQLS"
     gene            complement(3173..4918)
                     /locus_tag="VVR39_000073"
     CDS             complement(3173..4918)
                     /locus_tag="VVR39_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029637.1"
                     /translation="MKEKSPTAILWELAHDEHPKLKTSVFIASIGVLAGIVPYIAASR
                     ILVYLVNGIEDSKVYLMWLGIGLLSYALKSILYSLALSVSHKATFSVLKDIRLRMLDK
                     LPKMPLGEIINIPSGNLKQIIVDQVESMEKPLAHLLPEMTSNILGSLSIFIYLLFLDW
                     RMALLSLVSIPLGMFFMGLVMKNYAAQYEGSVKVSREMNSAIVEYVNGIEVIKTFNQD
                     KRSYAKYKDKVIANAKYFYEWMRSCQLPVSLSKNISPTTMITILPVGWYFYINGSLSI
                     ETFIVVIILSLGIAGPLLETMNFVDGLAKIGTIANSINSILEGKEQIHSNVDVKINKY
                     DIALQDVKFGYEEGKEILHGVSLNIEEGTTIAFVGPSGSGKSTLAKLIAGYWDINTGS
                     IKIGGYNLQEIPLKQLYSLVAFVSQDNFLFNESIRENIRMGNPSASDKEVENIAKKSG
                     CHDFIMNMEKGYDTVVGSSGSHISGGERQRISIARAMLKKSPIVILDEATSYIDPENE
                     VIIKEALSKLIQNKTVIVIAHRLSTITDVQQIFFVENGELISHGKHNELMEDCELYKK
                     MWNAHIGVKDGEIKC"
     gene            complement(4952..5797)
                     /locus_tag="VVR39_000074"
                     /pseudo
     CDS             complement(4952..5797)
                     /locus_tag="VVR39_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844950.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(5975..7192)
                     /locus_tag="VVR39_000075"
     CDS             complement(5975..7192)
                     /locus_tag="VVR39_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6029638.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(7274..7477)
                     /locus_tag="VVR39_000076"
     CDS             complement(7274..7477)
                     /locus_tag="VVR39_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU6029639.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            complement(7938..8168)
                     /locus_tag="VVR39_000077"
     CDS             complement(7938..8168)
                     /locus_tag="VVR39_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6029640.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            complement(8165..8587)
                     /locus_tag="VVR39_000078"
     CDS             complement(8165..8587)
                     /locus_tag="VVR39_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6029641.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            9092..9445
                     /locus_tag="VVR39_000079"
     CDS             9092..9445
                     /locus_tag="VVR39_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6029642.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            complement(9505..9672)
                     /locus_tag="VVR39_000080"
     CDS             complement(9505..9672)
                     /locus_tag="VVR39_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6029643.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(9791..11710)
                     /gene="tet(M)"
                     /locus_tag="VVR39_000081"
     CDS             complement(9791..11710)
                     /gene="tet(M)"
                     /locus_tag="VVR39_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6029644.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDYLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            complement(11726..11842)
                     /locus_tag="VVR39_000082"
     CDS             complement(11726..11842)
                     /locus_tag="VVR39_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6029645.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(12087..13019)
                     /locus_tag="VVR39_000083"
     CDS             complement(12087..13019)
                     /locus_tag="VVR39_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6029646.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            complement(13016..14017)
                     /locus_tag="VVR39_000084"
     CDS             complement(13016..14017)
                     /locus_tag="VVR39_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6029647.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            complement(14014..16191)
                     /locus_tag="VVR39_000085"
     CDS             complement(14014..16191)
                     /locus_tag="VVR39_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6029648.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYDPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            complement(16194..18641)
                     /locus_tag="VVR39_000086"
     CDS             complement(16194..18641)
                     /locus_tag="VVR39_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6029649.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(18625..19131)
                     /locus_tag="VVR39_000087"
     CDS             complement(18625..19131)
                     /locus_tag="VVR39_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6029650.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            complement(19106..19603)
                     /locus_tag="VVR39_000088"
     CDS             complement(19106..19603)
                     /locus_tag="VVR39_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6029651.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(19720..19941)
                     /locus_tag="VVR39_000089"
     CDS             complement(19720..19941)
                     /locus_tag="VVR39_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029652.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(19984..21189)
                     /locus_tag="VVR39_000090"
     CDS             complement(19984..21189)
                     /locus_tag="VVR39_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6029653.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(21212..21364)
                     /locus_tag="VVR39_000091"
     CDS             complement(21212..21364)
                     /locus_tag="VVR39_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6029654.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            complement(21367..22752)
                     /locus_tag="VVR39_000092"
     CDS             complement(21367..22752)
                     /locus_tag="VVR39_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6029655.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(22781..23167)
                     /locus_tag="VVR39_000093"
     CDS             complement(22781..23167)
                     /locus_tag="VVR39_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6029656.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(23183..23497)
                     /locus_tag="VVR39_000094"
     CDS             complement(23183..23497)
                     /locus_tag="VVR39_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6029657.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(23830..24387)
                     /locus_tag="VVR39_000095"
                     /pseudo
     CDS             complement(23830..24387)
                     /locus_tag="VVR39_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844950.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(24380..25081)
                     /locus_tag="VVR39_000096"
     CDS             complement(24380..25081)
                     /locus_tag="VVR39_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6029658.1"
                     /translation="MTIKLDFRTKLFMTIVLSYVMVLGNIQVKYFLQALIISVIPIVL
                     LINTKHTRVAIIGMATLVFVYGADRFLMKLEYSPLVAILLILVMVVKKILPAFLMGKY
                     TILTSNVGESIYSLKKMKCPDEIAIPLTVMVRFFYAARIDYSQIKKAMRLRGLTLKKL
                     IKNPILLFEYRLVPLLMCLSKTADDLTVSAMTKGLAVNQKRTSISESRIGGIDCIFFV
                     IMVWAIYLYIRGKYA"
     gene            complement(25102..25689)
                     /locus_tag="VVR39_000097"
     CDS             complement(25102..25689)
                     /locus_tag="VVR39_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6029659.1"
                     /translation="MSKRLEVKDLINIGLFSVLGFVFMMIGSFLGMVPVLMPVVPFAQ
                     GVLVGPVNMLYSTKIKKRGMVFIQSLLIALVYVAMGHGPWALLTAVIAGIIAEVILKS
                     GEYTDVNKARLAFSVAPLCTLGNWLPIFISRNEYVKQMLERGYKQEFIDKMLSVMPNW
                     IIVVMAIGGIIGAYIGCSIGMAFLKKHFKKAGMEK"
     gene            complement(25701..26291)
                     /locus_tag="VVR39_000098"
     CDS             complement(25701..26291)
                     /locus_tag="VVR39_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6029660.1"
                     /translation="MKEEKQKVGQIRKKEIREAAKKCFLNKGFQLTTMEDVITEVGMS
                     RGGVYHHYGNTNEMFKDLMLDGNDYRNNLINEYLKNNRGKDKYQQMGDILVDKSLADT
                     ELMRLYTLLLQAKKYNQDLEKLYQELKLNTTNELSLIAKQLGIKADIFGDGFLVNYIN
                     AMILSSEVLCARNSFSQHKKYIKETMVNYIVDIDKR"
     gene            26631..26981
                     /gene="mobC"
                     /locus_tag="VVR39_000099"
     CDS             26631..26981
                     /gene="mobC"
                     /locus_tag="VVR39_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEU6029661.1"
                     /translation="MANRMRNERLEIKLTEEEKALFEEKRKLAKCKNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQGLLSNATNNINQIAKRVNSTGIIYKDDINDMKKQIEHFSKELW
                     QIHSLLLNRTSGGD"
     gene            26987..28318
                     /locus_tag="VVR39_000100"
     CDS             26987..28318
                     /locus_tag="VVR39_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU6029662.1"
                     /translation="MAITKIHPIKSTLNLAISYIVNGEKTDEQILVSTHKCHQETAHT
                     QFLRTRNDAGTNGTVLARHLIQSFLPGETSPEIAHQIGLELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGKCYQSNKKSYHQIRYQSDKLCKDNNLSVIDEFYESYKRK
                     YKTNGKSWYENEQAKRGSSWKSKLQFDIDRLIKQSKDWEEFLKKMAELGYEIKHGKHI
                     AFKPKDKQKFTRAKTIGEDYTEERLRERITENQSIKAPPVKKRIGNVINMNTNAKVKE
                     SKGYEYWATKHNLNTMAESVVFIREHGIKSVKQLDECIKKSAEERQNLQDKIKKIDKD
                     MQLLSDTMEQVHTVKKYRAYYKEYKANPSDKAFFEEHKSEITRYETDLAKLKKSYSKL
                     PDSKDILDKLDKLQEKKNTLMQEYSSTKSTMDELYQIRKNYGIYMGKEMER"
     gene            complement(28392..29051)
                     /locus_tag="VVR39_000101"
     CDS             complement(28392..29051)
                     /locus_tag="VVR39_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6029663.1"
                     /translation="MDYKTMRNQIEDMVNDNHKDFVKAIISLEKGINNESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLVNIVGNIVGEVDVVEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNIRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQAEDKEKPKEKKEANKEAE
                     R"
     gene            complement(29094..37850)
                     /locus_tag="VVR39_000102"
     CDS             complement(29094..37850)
                     /locus_tag="VVR39_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6029664.1"
                     /translation="MRINDFHNILELIKQDVLQSEAEYLKLLKVVGNNQKYDFRSQLS
                     IYDKNPEATACAKFDYWREHFNRTVMRGQKGIPILEDYGTYKKVDYIFDISQTVSKNR
                     DVNEVNLWRFDKEAHRDVLKEMIKAEGYEESESTLENIFSLSRLYGDEKIDSLMNELR
                     ISDEDRISFTKFARDSVSYAVASRFKLDYPMDKELLKENFAMLDSISLMSLGETVSDI
                     SGTVIDATIQKSKELELQKEVLRGKEAGYNKIKEKLEEVEENVLRRDDQERISENERI
                     FRNGEYGRDNRENQREYTESVGGRDGLYEGISESDIRSDETGLSFKQRGAEQLRDVSG
                     SIQGEETDRASDGYAETSNRIYESREAETDGSLGDRGREPSAVQSDDFSPQRDDNQGN
                     SGNLKENTDKEIREADKASFSLPENRSGQIKLTIPLTQNDIDSILVNGGNHEGERLPI
                     IAEFSKGKTVEELGEYLKDTFRGGNGLFLNGAEVSSWYSDKGIHLAYGTSAREDMTQI
                     LSWSDAVRRINELLENGEFATNVELLEAHDYERDRVSESLWYLYHDLSEEGKAQGYFD
                     FMERGGEFPKETRQLSEALKNPDYLKNVISEYSRFLAGYKENRDVLRFHYHKVDSLYQ
                     KLQELELTRKEYTSNLIEPPKVQGFITEDEVLATISRGSGFDRGKERIIKFFKENHTL
                     QEKANFLKDEYGIGGGSHAVSGAKGSDEWHDAKGLKLQKNHCNDVFLTWSNVAKHIDE
                     LLSKNIYLEENKIESKTAIEEQKEPSYYSKGDPYNLMTDEMLEKVPELYAQEDVALAD
                     KQVHAAYIIPFRSNWTWYMTEYDRESKDAFGLVLGIEPEWGYFNLEELKELNAQRLIL
                     EDFPKTFRELRDSELKKQMDEQELHNVFNGELSFEENIADLEAPEEVEESIQAEPFQA
                     TLLDYLKEKEEVELNEKEDRSSDEFAVKEDDTVYFNHEEYKVREISKNPITGRNDLWL
                     DPARQGNHQIPIVAFTDNEDLLRQVSLERPDFIIGDEVKYKGKDYTITRFDDMGNNLK
                     TVTIKDNTEYLGGMITGSDVIPYRKESEIGKIFENLTYAKPEKTFEEAEIKKNQAHNF
                     KITEETLPSKLFPSERLNNNLEAISMLNRVESGERELDITAQEVLAKYVGWGGLADVF
                     DESKDGQWKEARAFLKENLSSSEYEAARESTLTSFYTPKTVIDGVYKTLSGMGFKQGN
                     ILEPSMGIGNFIGNLPDEMNQSKFYGVELDSVSGRIGKLLYPESDIQVKGLEETGFSN
                     NFFDVAIGNVPFGEYKVNDREYNRNNFLIHDYFFAKSIDKVRNGGVIAFITSSGTMDK
                     KDESVRRYLAARTEFIGAIRLPNDTFKGVAGTEVTSDIIFLKKRDSVLERDEDWIHLA
                     EDENGLSYNKYFVDHPEQVLGSMREVSGRFGKTLTCEPIAYLGTEINMASLKERIEIA
                     GERISKEAKYEEIELLDDEITSIPATDDVKNFSYTLIDDEVYYRENSLFIKKEVSDKN
                     KEKIKDYLELNAALKDVIYKQKEDFNEEEIKASQEKLNEVYDNFSKKHGFVNNLSNTR
                     ALKEDSNFPLVSSIEILDEEENFKAKGDIFSKRTITKAKIIDHVDTSLEALVLSVSEK
                     GYVDFDYMGSLTGKDRPTLIEELRGEIYLNIREEQNFYRPLSFNLEDGDLPFACANGS
                     NSYKYGYVTKDEYLSGNIRDKIVIVDSYLSKLRQTERELPHLGYEENGKEKELISYEM
                     NRLEYQKTELTKVLPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGYAKWDIKVK
                     FSNLTSEWNVEGKSKDRGNDLAEMTFGTNRVNAYKLIEDALNLKETKVFDQIVNPDGS
                     KTSVLNKKETMLAGQKQELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSN
                     LSFEGMNTEIDLRPHQRNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSK
                     SLFVVPNHLTGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYDAVVIGH
                     TQFEKIPMSKEYQEKHIQDQIDEIVNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKL
                     NDDFKKDDVITFEELGVDKLFVDEAHGFKNLYLYTKMRNVAGIGQSEAFKSSDMFMKC
                     RYMDEMTGGKGVVFATGTPVSNSMTELYTMQRYLQYESLKKNNLEHFDSWASTFGETQ
                     SSFELSPEGTGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEANYEVIKTE
                     PSEEQKEILKSLSERADDVRNRVVEPDVDNMLKITNDGKKLALDQRLINPLLPDNPDS
                     KVNVCVKNVFAIWDKTKENRSTQLLFSDMSTPKGDGEFNIYDDIREKLVSMGIPKEEI
                     AFIHEANSDKQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIAMHDLDVPWRPAD
                     LEQRAGRIVRQGNENEKVNIYRYVTENTFDSYLWQTIENKQKFISQIMTSKTPVRVAE
                     DVDESSLNYAEIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYP
                     EEIARTEKLIEAVKKDIASVEPKAEGEEKFTSITIAGEKITDKKLAGERLLEAISKVK
                     INESKVIGRYRNMDLEVSYNFFTNEHNFSLNGAAKHSGELGTSVDGNITRLDNALEKM
                     PEKLNRLEEKLISTKEQLENAKEELKKPFEKADELKTKVLRLAELNKLLDMGEVEEKR
                     NDNPLVEDVKRAIIDFCNREYEENHSYDEFNTLYPDLKHIGIAYTNTPDERHGIQYEL
                     NLEEKTWTQYIDDTPIKTESFDYESKGENEALRNMKNEMEMSSFSDLVYVDSEDLKAA
                     TGLEIDDEGNFYDPLSKDLDNDGIPDRYDNDFKDSDYFESTYDVEDNLHSKEETAQKS
                     EDKPSILGQIRAYQNESKTEEKQKTKEQEFLR"
     gene            complement(37937..39364)
                     /locus_tag="VVR39_000103"
     CDS             complement(37937..39364)
                     /locus_tag="VVR39_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEU6029665.1"
                     /translation="MTIDEIKKLIQNGEKIDVEFKESRNALTKDVFDTVCSFNNRNGG
                     HILLGVNDKRDIVGVSEDKVDKIIKEFTTSINNSQKMYPPLYLLPEVFELDSKKVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHAELVYKLYARKQGSYFVNKVYPNLDIEFL
                     DTDVIDKAKRMAVARNKNHVWENMSYEELLRSANLILTDPETKHEGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIAFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDEKIMIENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTRLYSGVDPLFEEGDIFRTIIPLKKIA
                     TQKVGGSGVAQDVAHSVAQDVAHDKIALAEFIKEKIRGNNKITRKAIADEAGVSVKTI
                     ERTIKEMDNLQYVGSGSNGHWELNE"
     gene            complement(39384..39563)
                     /locus_tag="VVR39_000104"
     CDS             complement(39384..39563)
                     /locus_tag="VVR39_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEU6029666.1"
                     /translation="MKDTFMDTAKVMSKGQVTIPKRIRELLDLQNGDYVTFVVNKDKV
                     QIQNSKTFIEENIDK"
     gene            complement(39647..41353)
                     /locus_tag="VVR39_000105"
     CDS             complement(39647..41353)
                     /locus_tag="VVR39_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEU6029667.1"
                     /translation="MNLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLI
                     KMANPESYDEKYAKWNMADLPIIPKEYKYEIAKSTKKQFTILKKLMNDKDIDIVINAC
                     DAGREGEAIFRLVYNQANCKKRMKRLWISSMEDSAIKEGFDNLKDGSSYDNLFESAQA
                     RAIADWLVGMNLSRLYSCLYKQNYSVGRVQTPTLAMIVKRDGEIANFKKEKYFTVELS
                     LNGFTLSTDRIDDEITAEQLLNLVGDKIEITDVIQKEKITKPELPFDLTTLQRECNKY
                     FGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMIVSTVNNILGKNDFDTERIKTVF
                     NSKKVTDHHAIIPTASSMNENLTSLPESELKVYELILNKLHASVGYPLIENTTKIVAE
                     FDGFEFTSSGKVIVDDGFTKYLNEYAKKKNEDTVLPDVKIGYSLDIKDKEIKEKYTQP
                     AKHFTEDLLLKAMELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNL
                     IATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGQSSEENFLEAIENEIKEVVSTY
                     TK"
     gene            complement(41451..43637)
                     /locus_tag="VVR39_000106"
     CDS             complement(41451..43637)
                     /locus_tag="VVR39_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEU6029668.1"
                     /translation="MKTSLKNKRITAIVVAFTLLMVGVLGVLKVGAKTVFASNEPPEK
                     YETYYELKFEDHTSDDTFRGFYHLGKGNKEGQPLNFKFSLSKSFEEKGGVVVDKYNET
                     FTNENMDKVNQLDDLRYMTKKPYPYYRIHNIGTGAFTSIVSPRDKDNYYIGDITENAE
                     ERTVKGKKANVIVYTCPVLQLNRNIEKVTVDYEGEFKEETKNSIIGRVKEANPNINNV
                     KEIKIVKDKLIIETWNRFHTGVPYLELPLEDLYKRVANASAQTDNKDTKDEESQTKSE
                     VKIKYQYQDGNVYKEYSASFDKNQMIDASDLEMLPDNMSFNDDFVSYTVKGDGSDSII
                     RIVKKLESNAQTQTEKPKTEDKGIQTELSKDDISKMEKESKELQEKLDKLNQEIKDKD
                     KLSDKQKEKIKDLEEKIDKLKEKLEKGKDDKDLSADIKKEIEKLTEKIKELEKKTNEV
                     GKATVTHNPTVTPISPISGMKTGTGNFPQTSVSDTGKGSSSQDNTGKITKDTNIGKNN
                     DKEKEVRYPNKLTPKQPANNSSQDSSMDGSSKNVNTNKGVASAPSKARGTVTENKDNA
                     NKDYPIHHNDSKDNKETDMYSADARQFVTFTTKNGKTFHLIINHDEDSENVMLLTEVS
                     EDDLLNMVEKKEAPKQEITKEEPEKEEPKPVKKEESSNMGTYLILILVVAGALGAGYY
                     FKVVKKKEDKELEGFEEEDDDFFSEAEESENEVDETETEDKEDELE"
     gene            complement(43615..43851)
                     /locus_tag="VVR39_000107"
     CDS             complement(43615..43851)
                     /locus_tag="VVR39_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6029669.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLMAKVNREKAEVKKEKTNENQFEK"
     gene            complement(43864..45996)
                     /locus_tag="VVR39_000108"
     CDS             complement(43864..45996)
                     /locus_tag="VVR39_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6029670.1"
                     /translation="MGKKLKKDFKERQRARIEKERLQSNSSIEPEENKLKHNDDYRGK
                     IVHDKDRFQDKVHEKVSKRSAETELNGKTSKRNARYRSPETGSVSQEEIGKADYDTEV
                     KDGKIYDPLGKDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLQHKVEDTKGFSKSQKA
                     QKKNYKRKNYSDKLYTRKKDKEAKEEKADSKKSGKEAILDREKKNRLSKEQERAFKNK
                     TSKVSALSGLAKGSETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKKAK
                     KGYDLTNKDYKIRKRKSKLEFRDAKEELKKTQEYQKANNFKRFQKRKQMKDSIKRKNK
                     SRLRDRIKEGLIGSLKSSKEVILRKAKGLMIIFIGLIILGTFFINFAGTGMTGFMNST
                     SSVLTTSYLSKPNVLSEINENFSEMEKELQSEVDNVEENYPGYDEYILNNTEYIGHNV
                     HELLSYITSRCGEVKNASEVSSVLNELFKSMYDLEYKEEVEIRYRTVTETYTDEDGNE
                     YTESHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMGEAFGNS
                     DLIASNGGIGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGG
                     NACDMYRNYTFTSDKSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGRI
                     RVTTLDDWIASFCQHHPVGFGFPPNVNR"
     gene            complement(46001..48430)
                     /locus_tag="VVR39_000109"
     CDS             complement(46001..48430)
                     /locus_tag="VVR39_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6029671.1"
                     /translation="MKDKRKIQQLKLEQNQKKLRSQKQDLKQNKGKSKKDRGGLLDLI
                     FRKEPKRYTVEDTIPYLRLLKSGICQIDEKHFNKSIAFEDINYQLALEEDRDLIFNQF
                     ANFLNSFDPSVSIEFSYINQLGRNEEMKSAIQIPDKKDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFEFSYKDLKKKESTKTYIAPDEFNFTPSRYFKFGKFIGAASHFQILASELS
                     DRMLAEFLDIDDNINISFHIKAIEQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVTIIFMNFARTIQRLDNTISQISSIANKH
                     NCKLKRLDHSQEQGLISVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSANSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILTTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFENPKPCNMPILQNLYDMLKNQEEKVGKKLATEMEIY
                     VTGSLNVFNHQSNVDLNKQLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISQPQLKYVTNSNAGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(48342..48731)
                     /locus_tag="VVR39_000110"
     CDS             complement(48342..48731)
                     /locus_tag="VVR39_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU6029672.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLIGIPIYLFMR
                     KVVPNDIAVIFLIVSTLPIFFITLFEKDGLSFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     RQKKNSAAKVRTKPKEVKKSKTGLKAK"
     gene            complement(48735..48998)
                     /locus_tag="VVR39_000111"
     CDS             complement(48735..48998)
                     /locus_tag="VVR39_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6029673.1"
                     /translation="MNKRKTVLIAVAVGTGILAVMDRIRLHIKENDLEERTKDIGRCH
                     NDFCLMQERYNRSTDEQIASIQEEIGSVYEHIEELSKGKEDGR"
     gene            complement(49016..49879)
                     /locus_tag="VVR39_000112"
     CDS             complement(49016..49879)
                     /locus_tag="VVR39_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029674.1"
                     /translation="MFGIFDKIEEFFKDLLLGGIQANLESMFLDINDKVGAIATDVGK
                     TPMGWNGQVFSFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFQFSMAVFDVAQHMVNKAAGVINTSAVISGDQIVTMVEGLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYVYSSVSAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIQITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            complement(49899..50114)
                     /locus_tag="VVR39_000113"
     CDS             complement(49899..50114)
                     /locus_tag="VVR39_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEU6029675.1"
                     /translation="MEFFTQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLK"
     gene            complement(50118..50429)
                     /locus_tag="VVR39_000114"
     CDS             complement(50118..50429)
                     /locus_tag="VVR39_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6029676.1"
                     /translation="MKQEMININANLLAEPTFSSFDKEGETVEVVNFTLVKKYGKGKE
                     YINCAAYGEKSETAKAFEKGDLIHIFGYFKKREKDGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(50595..52379)
                     /locus_tag="VVR39_000115"
     CDS             complement(50595..52379)
                     /locus_tag="VVR39_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU6029677.1"
                     /translation="MIDKILKDIKGLFKVQDKSKFFKQNIPYLAFFYVGNIFSHHVRA
                     YTGGDVIDKIFQGILELNTMSFIPSIHPIDILMGVEVAVLIKFIVYTKGKNAKKFRQG
                     KEYGSARWGTRKDIEPYVDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVIECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKAGEDFWVKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDDETYMNPIDRLFEALEKKEPTHFAVKQYKKYKLAAGKTAKS
                     ILISCGARLAPFDIQELRDLMKEDELELDTLGDRKTALFVIISDTDDTFNFVVSIMYS
                     QLFNLLCDKADDEYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQA
                     QSQLKAIYKDNADTIVGNCDSTLFLGGKEKTTLKELSETLGKETIDLYNTSETRSNAN
                     SYGLNYQKTGKELMSQDEITVMDGSKCIFQLRGVRPFLSDKFDITKHKNYKLLEDFNK
                     KNAFDIEEYIKRKGKAKLNRETVITRVQ"
     gene            complement(52376..52861)
                     /locus_tag="VVR39_000116"
     CDS             complement(52376..52861)
                     /locus_tag="VVR39_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU6029678.1"
                     /translation="MINEEIARKTLNMEVKAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKESGKYSVF
                     FQAKDMKVMDKAFKHALSESEKKTERKESIHKNIEKFKEMAKNALSKDKVKNKQKEQS
                     L"
     gene            complement(52858..53709)
                     /locus_tag="VVR39_000117"
     CDS             complement(52858..53709)
                     /locus_tag="VVR39_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6029679.1"
                     /translation="MIKELEKVMIEDVEYSFNPEKEYIKDGHAYCKVCHERKDGKALE
                     FFGKQMIFKTACKCDRDREAKEKERQKQLEIERLKSICFTSIIQWSYTFENYQGKENQ
                     SLIIAKNFVKDYELMKKENIGLLFYGTVGSGKTYLACSIANALIEQYQISVKIRNFSQ
                     IINELQKGGFDIDKNAYIESLVNTSVLILDDLGIERDTSYAKEQVYNIVNNRYLKHKP
                     TIFTTNLSYSQIENCTESVEYQRIYSRIIEMCIPVMVLGENYRKVIQEEKLKRNKERL
                     LTGGERT"
     gene            complement(53706..54476)
                     /locus_tag="VVR39_000118"
     CDS             complement(53706..54476)
                     /locus_tag="VVR39_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6029680.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWVDKEGRVFIYFTVEEIMRRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNVIYVKDFMSIIAVKENDFQKSKNLTSEVRDFNLRSKENELQEVQNVDSNYI
                     ENNKSKYSKREYSFGKSGLGTFQNVFLKDEDIGELQIIMAGELDNYIERLSTYLQSTG
                     KTYKDHKATILSWFYKDQGSKKKTNIPTWEEYNKGVHL"
     gene            complement(54567..54848)
                     /locus_tag="VVR39_000119"
     CDS             complement(54567..54848)
                     /locus_tag="VVR39_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029681.1"
                     /translation="MRWIIKIILFPISLVLSILTAFLTFLLGIGTALLYLLMMFCIFG
                     AIASFLQKEVTIGIEALIIGFLVSPYGIPMVGATVIAFLQGINEAIKSI"
     gene            complement(55013..56371)
                     /gene="rlmD"
                     /locus_tag="VVR39_000120"
     CDS             complement(55013..56371)
                     /gene="rlmD"
                     /locus_tag="VVR39_000120"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6029682.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECIALIQR
                     VK"
     gene            complement(56445..57419)
                     /locus_tag="VVR39_000121"
     CDS             complement(56445..57419)
                     /locus_tag="VVR39_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU6029683.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKTLSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(57493..58107)
                     /gene="pmp23"
                     /locus_tag="VVR39_000122"
     CDS             complement(57493..58107)
                     /gene="pmp23"
                     /locus_tag="VVR39_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU6029684.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(58107..59081)
                     /locus_tag="VVR39_000123"
     CDS             complement(58107..59081)
                     /locus_tag="VVR39_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU6029685.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(59089..60345)
                     /locus_tag="VVR39_000124"
     CDS             complement(59089..60345)
                     /locus_tag="VVR39_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU6029686.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITAREFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(60407..60838)
                     /locus_tag="VVR39_000125"
     CDS             complement(60407..60838)
                     /locus_tag="VVR39_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029687.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(60840..61442)
                     /locus_tag="VVR39_000126"
     CDS             complement(60840..61442)
                     /locus_tag="VVR39_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU6029688.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(61426..62265)
                     /gene="prmC"
                     /locus_tag="VVR39_000127"
                     /pseudo
     CDS             complement(61426..62265)
                     /gene="prmC"
                     /locus_tag="VVR39_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
     gene            complement(62265..63344)
                     /gene="prfA"
                     /locus_tag="VVR39_000128"
     CDS             complement(62265..63344)
                     /gene="prfA"
                     /locus_tag="VVR39_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU6029689.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(63354..63833)
                     /locus_tag="VVR39_000129"
     CDS             complement(63354..63833)
                     /locus_tag="VVR39_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029690.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(63823..64422)
                     /locus_tag="VVR39_000130"
     CDS             complement(63823..64422)
                     /locus_tag="VVR39_000130"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU6029691.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            64545..64727
                     /locus_tag="VVR39_000131"
     CDS             64545..64727
                     /locus_tag="VVR39_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU6029692.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            64864..66237
                     /gene="mnmE"
                     /locus_tag="VVR39_000132"
     CDS             64864..66237
                     /gene="mnmE"
                     /locus_tag="VVR39_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU6029693.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(66284..67219)
                     /gene="dapA"
                     /locus_tag="VVR39_000133"
     CDS             complement(66284..67219)
                     /gene="dapA"
                     /locus_tag="VVR39_000133"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU6029694.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(67275..68351)
                     /locus_tag="VVR39_000134"
     CDS             complement(67275..68351)
                     /locus_tag="VVR39_000134"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU6029695.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(68693..68765)
                     /locus_tag="VVR39_000135"
     tRNA            complement(68693..68765)
                     /locus_tag="VVR39_000135"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68730..68732),aa:Thr,seq:ggt)
     gene            complement(68865..69374)
                     /locus_tag="VVR39_000136"
     CDS             complement(68865..69374)
                     /locus_tag="VVR39_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU6029696.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(69372..69468)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            69497..69928
                     /locus_tag="VVR39_000137"
     CDS             69497..69928
                     /locus_tag="VVR39_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU6029697.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            70010..70387
                     /gene="mscL"
                     /locus_tag="VVR39_000138"
     CDS             70010..70387
                     /gene="mscL"
                     /locus_tag="VVR39_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU6029698.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(70429..71523)
                     /gene="hemH"
                     /locus_tag="VVR39_000139"
     CDS             complement(70429..71523)
                     /gene="hemH"
                     /locus_tag="VVR39_000139"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU6029699.1"
                     /translation="MKKAILMMTFGSPEETTFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITHQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKIIFSAHSVPIFALDFGDPYIDQIFENSKLVVEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTAHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            71677..72900
                     /gene="pepT"
                     /locus_tag="VVR39_000140"
     CDS             71677..72900
                     /gene="pepT"
                     /locus_tag="VVR39_000140"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU6029700.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(72936..73565)
                     /locus_tag="VVR39_000141"
     CDS             complement(72936..73565)
                     /locus_tag="VVR39_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029701.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            73530..73751
                     /locus_tag="VVR39_000142"
     CDS             73530..73751
                     /locus_tag="VVR39_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029702.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(73828..74369)
                     /locus_tag="VVR39_000143"
                     /pseudo
     CDS             complement(73828..74369)
                     /locus_tag="VVR39_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(74473..75017)
                     /locus_tag="VVR39_000144"
                     /pseudo
     CDS             complement(74473..75017)
                     /locus_tag="VVR39_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT        21230 a        15766 c        12225 g        25796 t
ORIGIN      
        1 atatatcaaa cctttctaat agtttatttt cacctttgga taataagata cttaacaatt
       61 tatcgcttct tcttttccaa tttttctaag tctgctaagc attaaaaaca agccgagcaa
      121 aatcatacta aaatctacaa taggttcagc ccaccaaact gctaatcctc caaatacctt
      181 tggcaatagc aatatcgccg gaataaataa aatcagttgt ctaagcatta caatcatgct
      241 tgcttttttc ccatctccaa tagattggaa aaatgtaaga gtcataatca taattccata
      301 caggataaag gtagaataga acaatttaaa gttcataact ccagcttcaa ttatttcact
      361 tctcacatta aacaatgaca ataatttttc ggagaaaaac atggatggta tccaagaaat
      421 agcagcaagt attgttgccc catacatgaa aatcttcata gtatctttta ctctttgata
      481 ttgttttgct ccaaaattgg ctcctataac aggctgtaac ccttgactca ttccccacaa
      541 tggaataaat gagaacatat aaagtctcat tgttgcagac attagaattc cccaattatc
      601 tccaccataa gcgaaagcct gtttgaacaa aaatgtttgt tgtactgcaa ataaaatttg
      661 catcatcata gccgaacttc ctatactaaa catttcactg tagattgcct tgctcttttg
      721 aattttatgg ataccaacaa aagcactttt ctttgaaaaa tagtgaaatg ttaatatcgc
      781 ctgtacaatt tgagatatta cagttgcaat ggctgcacct tcaattgcat actctcccat
      841 caacttcata aaaataggat ctaaaataat atttaataaa gcacctactc ccataatcat
      901 catagattgc ttcaatgcac cttcaccacg cattgtcata ttgcctgctt gagcaaaatt
      961 cacaaatatt gaaccaaaga aaactactct taaatatcta actcccagtt ctttaatatt
     1021 tccttttgct cctaccaaat ccagaaaatt aggtgcaaat accaagccta atactgtgat
     1081 tactatagag aataaaatta cccaataaca aaaatttcca aatattttat ccgttgtttc
     1141 tttatctccc tttccaatag cccttgacaa aatcgacgca ctaccaactc caataagtgc
     1201 tgatatacca ccatttatta ttgttaaaga catcgatata ctaatggcag acatagcata
     1261 atcccctata atccacccag caaatattcc atccataaat ggataaagtc ctataacaac
     1321 cattcctata attcctggaa tagctaattg aaacaataaa tctttaggac tttttgttaa
     1381 aagttgtgtt ttcatatctt gttttcccat atgacttcct cctattgttt ttaatatttt
     1441 tcagcttatg ataactgcca cttggttgct acttgtcttg cttcaacaaa atttctgtaa
     1501 ataccatctg tttgaattag ttcttcgtgt gttccttttt gcattatctt tccattagcc
     1561 aatacaagaa tttgatttgc attttttata gtttttagcc tatgtgcaat cataatcaca
     1621 gttttatttc tcgtaagttc ctccattgca agctgtaatt tatcctcatt ttcaggatca
     1681 acatttgctg tggcttcatc aaaaataata attggggcat tttttatcat agctcttgct
     1741 attgaaattc tttgtttttc accacctgat aaacttgcac caccttctcc tataacagtt
     1801 tggtattgtt caggaaggtt cataataaaa tcatgacagc aagccttttt agcagcatct
     1861 actacttctt catgggtagc attaggctta gcaaacttta tattattttc tatagtatct
     1921 tggaacaaat acacattttg gaaaaccata ctgatttgtt tcatcaatga ctctaaggaa
     1981 tattccttta tattatgtcc tcctatacta atcttcccgt tatctatatc ccaaaacctt
     2041 gcaatcaagt tacaaaatgt ggtttttcca gctcctgaag gtccgactat tgcagtcatt
     2101 tggttttgtg gtatatcaac agatatatca tcaagaattt tctttcctga atatgcaaat
     2161 tctacatttt caaaagaaat attaaaatta gcaggtttta tatcttttcc ttcaatatcc
     2221 atttgtggaa attcttctaa tttcttggtt tgttcaatag agccactaac aaccctaagg
     2281 gcagttgtcg cacttcctgc caatttaatt tgtgaaaaag caagaaatga aattatgatt
     2341 gtcataactg tattcagaaa cgaaagttct cctctttggt agaagaaaat acctgcacct
     2401 atgattaaaa tgctgaacaa atctaaaaga atattttgaa caatcgtgta aggtgtaaac
     2461 aacttttcac aatcaagatt tgtttttctg gtattttcaa tagcacctct aactttctca
     2521 tcacctttac cggttaaatt aaaggatttt ataacagaca ttcctccaat ctgttctaaa
     2581 acagtatcta ctaattttgc tgaagccatt tgtcgtttag gaagaacctc tcttgacttc
     2641 ttttccattt ttgacaaaat aaccaaatat aatagacttc cgacagttac aataaaacct
     2701 attctccatt caaatattaa aatcatcaaa gtaaagatta tagtatttat aaatcccgac
     2761 aaggtattta ccataaccat cgcagccgta ttttccacat cttctaaaac ggttgtagaa
     2821 ataccaacga cttctccccc attgtttcca ttaaaaaatc ccataggaat ttttttgaac
     2881 atttccccta ttgaaattct tttatttgca accataaaat agcttgcatg gcattgttgt
     2941 aactgtgaat aataatttgc aatacttctg cctactatgc ttacaacaag aagtatcaaa
     3001 gcaatccacg caggtgtcat actcatatct ttttcagaaa cagctttaac tataaaataa
     3061 attgcactga tttgaagcat gtgaaaaatt gcaaacaaga aacttaccca tatagaatgg
     3121 tatatatttt tcttctcatc acctgagaaa tctaaaattt tttttaaagc acttagcatt
     3181 ttatttcacc atcctttact ccaatatgag cattccacat ttttttatat agctcacaat
     3241 cttccattaa ctcgttatgt ttaccatgtg aaataagctc tccattctca acaaaaaaga
     3301 tttgttgaac atctgttatt gttgataacc tgtgtgcaat aacgataaca gttttatttt
     3361 gtatcaattt tgatagagct tctttgataa tcacctcatt ctccggatca atatatgaag
     3421 ttgcttcatc caatatcact atcggggatt ttttaagcat tgctcttgct attgagattc
     3481 tttgtctttc tcctccggaa atatggctac cactgcttcc gacaactgtg tcatagcctt
     3541 tttccatatt cataataaaa tcatggcagc ctgacttctt tgcaatattt tcaacttctt
     3601 tatcacttgc acttggattt cccattcgta tgttttccct aatgctttca ttaaaaagga
     3661 aattgtcttg agaaacaaat gctactaagc tatataactg tttaagagga atctcttgga
     3721 gattatatcc accaattttt atgcttcctg tatttatgtc ccaatatcct gctatcagtt
     3781 ttgccaaagt tgactttcca ctaccgctcg gtccaacaaa agctatcgtt gtcccttctt
     3841 ctatgtttaa cgacactcca tgaagaattt cctttccttc ttcatatcca aacttcacat
     3901 cttgcagagc aatatcatat ttgtttattt tcacatcaac attggaatga atttgctctt
     3961 ttccttctaa aattgaatta atagaatttg caatagttcc tatctttgca agaccatcaa
     4021 caaaattcat cgtttcaagt aaaggtcctg caattcctaa cgacaaaata ataactacta
     4081 taaatgtttc tatactcaaa cttccattga tgtaaaaata ccagccaacc ggaaggattg
     4141 ttatcattgt agtaggcgat atattttttg ataaagacac aggaagttga cagcttctca
     4201 tccattcata gaaatacttt gcatttgcaa taaccttatc tttatatttt gcatatgacc
     4261 ttttatcctg attgaaggtt ttgatcactt ctattccgtt aacatactcc acaattgccg
     4321 agttcatttc acgactaact tttacagatc cttcatactg agcagcgtag tttttcatca
     4381 caagtcccat gaaaaacatt cctaaaggaa tagaaactaa tgacaataac gccattctcc
     4441 agtcaagaaa taacaaatat atgaatatac tcaaagagcc taatatattg gatgtcattt
     4501 caggtaataa gtgtgcaaga ggtttctcca tactttcgac ctgatcgact ataatttgct
     4561 ttaaattacc gcttggaata tttattattt ctcccaatgg catctttgga agtttatcaa
     4621 gcattcttaa acgaatatct tttagtacac taaaagtcgc tttatgagat actgataatg
     4681 ctaaagaata taaaattgat ttcaaagcat atgatagcaa gcctatgcca agccacataa
     4741 gataaacctt gctgtcttca attccattca ctaaataaac taaaatgcga cttgccgcaa
     4801 tgtatggaac aatccccgct aaaacaccaa tactcgctat aaatactgat gtctttaatt
     4861 ttggatgttc atcatgtgca agctcccaca atattgcagt aggacttttt tctttcattt
     4921 caacacctcc atagttctat ctatttacat ttcatttcaa aaattcatat attgcaccat
     4981 cgcattgttt tataaattca aaatcatgcg tgattataat aatagttttt ccttgctcta
     5041 ccatttgatt taaaaatcca atcaaaatat ccatttgcat tttgcaaagt ccactcgttg
     5101 gctcatcaaa cactatgatt ggtttttgac ttaccataga catagcaagc aacaatctct
     5161 gtttttcacc acctgataac gaacttgggt gcatttcttt tttattaaat aaatgtacct
     5221 ttcttaaggc ttcatttttc aaattatcct gttttgtaac tgttccaatt tcctgccata
     5281 cagattctgt gaaaagttga taattaacat cttgcatgac tgcaaagata ttctcgtacc
     5341 gttttttgag cttttctccc ttataaaaaa cttctccctt gccttttata gttcccataa
     5401 gtaaattgat aaaagtactt ttcccaacac cgttttgtcc aataatgaaa tttatcccgg
     5461 tattaaaaga aacactaaaa tcaaaaattg tattcttatc gtatgttttt ttgaaatgta
     5521 gacatgttat tgattcatta acaaagtttg atggagtatt tttttgtaac atatctactt
     5581 tttcatattg tctatttaag aaatcactct taaaaatttc attgaaattt cttaaattat
     5641 gtttttctga aactcttaca aagaaatcat cactaaaata ttctttcgtg tattctttaa
     5701 aagttttatt ttctattaca cacagcttgt ctacaatgtc tttcaaataa aataatctat
     5761 gctcgacaat gattatgatt ttatttcttt tttttaatat aaacaaagta taaatttcta
     5821 attatctttt tatattttct taaatgctcg taaagcctta ttctatgtgc tttcgagtat
     5881 ttttactgta ggaagatact tcacgtttct ttgcatattt cctcatgtct tagctgtcag
     5941 aagtggtaaa taagtagtaa attcatttgt actactaagc aacaagacgc tcctgttgct
     6001 tctctttatt caagcgtttc atttctgcca ttgcagaatc gaatgttgca tgtgcgtaat
     6061 agttcagcgt catggctata ttagcatgtc ccataatgta ctgtaatgcc tttggattca
     6121 ttcctgcatt tgcatagttg gtacagaatg tatgtcgcaa actatgtgga gtgatgtgtg
     6181 gcaatttatc ctcgttatac ttattgtatt tcttaacaag acctttcatc atgccgttgt
     6241 aatcacttgc cacttttgga tagttctttc tattaagaaa gagaaaatca ctatatccat
     6301 caatctcaac acgcttatca ttctttcgat tcgctaacac tcgcttaaat gcttgatagg
     6361 cttcttcaac cataggaact tgacgttcgc cacttttggt ctttggtgtt tcaatgtagt
     6421 acccaatttc agtatctctc aatagctgat ggtctatatt gacaagacga ttctcaaaat
     6481 ctaaatctgg aagtgtcaaa ccaccaaact ctgaaatacg aagacctgtt tttaagagta
     6541 tcagaatttc atcataattt ttgctgtagg ttttatcagc ttttgcaaag gctaacagtt
     6601 tttcttcctg ttcttctgtt agtacggtct tagggacagt atcatcatca agaactgctt
     6661 tcagttgaaa gtcaaatgga ttcttccgaa cacaatcatc ttgtatagca atatagaatg
     6721 aagcctttaa agaacgtttg tagttattga tggtttgata agcataacca ttttcactca
     6781 ttctaatagc ccattcttta gcgtctgatg gcttaatact gtcaatactt cttacaccta
     6841 acttgtcttt cttcaaaata tccataagat atttgcgtcc agtttcagtg ttttttctaa
     6901 cctttggtct ttgagcgttc tgttttgcgt aaagctggca gagtgtcatt ttctttccta
     6961 caacatcaat accatcatga atgtctttct gtaactctgc gattttctct ctaagtgaga
     7021 tacaatcacg ctttcctgct ggtactcggt ctgtagccac aagtttccac gagtaaacaa
     7081 attgcggttc tccaaatgaa tctatatatt tgtataagta tcttccgtct tttcgttggc
     7141 tctctccagt ctttaagatt cgacctttat tgtcacgtct tttttctgac atggcatttg
     7201 ctcctttcct ttatggaaag agccttgata cgacttaata ctattttatc atatacaaga
     7261 ccctttggcg acgctagatt gcgtccaatg tatctataat tttttcaaat tgttttcgtt
     7321 taatctgaat acgattgcca ttcataatca gccaatttgc atttttattt tcctctgcca
     7381 agcgtcgtag cttgttttcg ccaatacgaa aatattttga cgcttcttca atggttaggg
     7441 tataacgttc ccaaatagga atgtcagtct gcttcataaa atcctccttt ccaaatcact
     7501 tatttggatt tcataaaagt tgttttacca gcaatcgaac agctttagca aagctcacgg
     7561 gagttccacc cctgcatggt tctcatgtag ccatactcat tgcctgcgac ggttttatca
     7621 cgctcggact attgactgta tgggagtatc attatcacga taagaatgtc gttgcaggca
     7681 atcctgctaa agattgcttc tcggatcact aacatgaatc gctcgctatc tttataagat
     7741 aggtcatggc ggttagttcc gttggctctt ttcttatcga aacgtattcg attactttta
     7801 ttcagttttc aaagaacaat ggctcgttag cctatcaaaa cacattgaaa gctcaatatg
     7861 ctttggtgga ataacaaacc tccctgttcg ggaagcgtgg aatggtttag cacgcttcca
     7921 cgaaaggaga gaggatatta cttaatttca aatgacaaaa tctttgtaat cagtctggtt
     7981 tccattcttc cacgtaagac ttcatcaacg accatacttt gattgccata ttcatctttc
     8041 ataagtcgta gggaacgctt cgttatgtac cctctgtaat gatgtagaat ctggttaatc
     8101 gcttcggtat cgccatctgt tgcctttaca atgagaggaa agggaatcat aggatattgt
     8161 gttttcattc ttcaaattcc tccataaact ttttaattaa ggctagtcca ctggttctat
     8221 gccgatagac agtagaacgg ttcaatttca acaggtctgc aatttctgaa tcgctcatgt
     8281 ccataaagta aaacagcagt agaatttcac gtttcttgtc tggcaactca cgtaatgctt
     8341 cactcaacaa atcattttca acgcctactg ataacccatt gagtgtaaaa atctgaaagt
     8401 cagttgaata gttatctgtt gtcgcaaact ggctaacaag ataatcgcca acatccgaaa
     8461 aggacacctc acgctttgca atccttgaaa gataaagcat ataattcttt cgctcgtctt
     8521 ccatagcacg tttacagata tagtcaaact gattttctat tgtggtctga aaagaagatg
     8581 gtttcatgtt tctcaccccc tttctgtcta ggaaaggaag tgagccttgc tcgtttatct
     8641 cctttcactc ttagtcccaa tgtgaaaggg ggatttgttg cattactgat aaataaactt
     8701 tgtaaaaaag ttctgaatag ccaaaaaagc atataaacag atttatttct ctgtttacat
     8761 gcttctgtta ttctatctat atgatttata aaaccacatt ggtggacgta cttatctatt
     8821 gcagatagac gacttttttt gacaagaacc caatgtaagg aaatttattg tatatgatgt
     8881 acttcatggc gacgttgacc tccaacaaac cgccatttgg aagtaatata caatatttta
     8941 acagcgtaaa tagcactacc atataacggt tttttttatt ggcgtttagt agtgcttttt
     9001 attaaatata aacctataaa ccatataaca cgtttttcta tacctgtttt taattcagta
     9061 ggaacaataa aatgtataga ggtggtctac tatgcgtaaa aaagaagata aatatgattt
     9121 tagagccttt ggtttagcca ttaaagaagc tcgattgaaa cgaggtttaa ctcgtgaaca
     9181 agtgggagca ttgattgaaa ttgacccacg gtacttaact aatattgaaa ataaagggca
     9241 acaccccagc atacaagttc tttatgacct tgtatcgtta cttcatgttt ccgttgatga
     9301 atttttctta cctgctaata acttggtaaa aagcacccga cgattacaga tagagaaata
     9361 catggatagc tttacagaca aagaactatc cttaatggaa tctttagcca gcggtatcaa
     9421 cgaagcaaga aacatcgaag actaattaaa agaatccata cataacggaa agagccgata
     9481 aaatgagatt gtattaatct cattttatcg gctctgcgtc tttgcgtctg gctctgtaat
     9541 cacagttact ttgaactgct ttatttcaat taaattttct tgtctgcatt tcggacaata
     9601 gagggggaat ttttttaatt cagtatcttc ccttatcttt aatcgtgttt tatttccaca
     9661 tacaggacac aatatccact tgtagtttat aataactatc tcctccttta cactttaatt
     9721 caaatcttta ttaaaaaata tttcatctta tttaacaaga aaccatattt atataacaac
     9781 ataaaataca ctaagttatt ttattgaaca tatatcgtac tttatctatc cgactatttg
     9841 gacgacgggg ctggcaaaca ggttcaccgg tagtaacatg gtaccctttt aactctgtta
     9901 aacaaacact acgtccattt gtaaagaaag ttaaatcact acgatattct tgaatacacc
     9961 gagcagggat ttctccacta agaatgacct cattattttt caattgagtg tctacgatgt
    10021 tcgcacaata tttaggagca tcgttgtatg ctcgtgaaag atattcctgt ggcgcataaa
    10081 ttttaaaact aagatatggc tctaacaatt ctgttccagc tttttttaag acttgttcca
    10141 atacaatagg agcaagcatc cgaaaatctg ctggggtact aacagggcta tagtataagc
    10201 catacttaaa acagatttta cagtccgtca cattccaacc atacaatcct tgttcacagc
    10261 catagcgtat cccctccata actgcatttt gaaacgattg atttaagtat ccaagagaaa
    10321 ccgagctctc atactgcatt ccacttccca acggaagcgg tgatacagat aaaccaatgg
    10381 aagcccagaa aggatttggc ggcacttcga tgtgaatggt atattctgca ttttttaacg
    10441 gtctctccat ataaatgact gtaggctctt ttagttctat ctccacatga tacttttctt
    10501 gcaacagtgc actaatcact tccatttgta ctttccctaa gaaagaaagt ataatttcat
    10561 gtgtcgtaga atccacgtaa tatcgtagaa gcggatcact atctgagatt tccaaaaggg
    10621 catcaagcaa catttctctc tgttcaggtt tactcggttc aacagttgtt tgtagtagag
    10681 ggtgcggatt ttcaatcttt tttctctgtg gcaatagttt tgtatctcca agaacactat
    10741 ttaacttcaa aaactcattt tgcaaaataa caatttctcc agaataagct ctatcaatct
    10801 tacataattc accatttatt gaagtataca tttctgtaac ttttattttt tctttttctg
    10861 atactctaac cgaatctcgt aaatgtagta ctccactata aaggcgtata tatgcaagac
    10921 gttgtctttt ttttgtatat tcaattttga aaacatttcc gcaaagttca gacggacctc
    10981 gatgtgttga tgaataaaat ttattagtaa taacttctat aaggttatca atccctatat
    11041 tactttttgc acttccatga taaagaggga acagagaaca attctgaaat cttatgcttt
    11101 cctcttgttc gagttccaat gcttctaatg atttaccgga catatatttc tctaaaaggt
    11161 aatcgtttcc ctctattacc gtatcccatt gttcagattc ggtaaagttc gtcacacaca
    11221 tattaggata cagttctacc ttctgtttga ttacaatttc ggcagaaagt ttctctttaa
    11281 tatcctgata aaccgttgat aaatcaattc cattttggtc aatcttattg ataaaaaaga
    11341 ttgtgggaat ccccattttc ctaagtgcat gaaataatat acgagtttgt gcttgtacgc
    11401 catcttttgc agaaatcagt agaattgccc catctaaaac tgataatgaa cgatatactt
    11461 ctgctaagaa atccatatgt cctggcgtgt ctatgatgtt caccttcgta ttttcccact
    11521 gaaaagaggt tattcctgtc tgaattgtaa ttcctctctg acgttctaaa agcgtattat
    11581 ccgtcctcgt tgtacctttg tccacgcttc ctaattctgt aatcgctcca ctgttatata
    11641 ataagctttc tgttaaggta gtttttcctg catcaacatg agctaaaact ccaatattaa
    11701 taattttcat gtgattttcc tccattcaaa aacccaaaag ggcataaaaa tcccagtgat
    11761 aaatactttt atcactggga tttttatgca taaccatagg catacaaagc atacagatat
    11821 tctccggata ctttagaatc acatgataaa ggtattctta aactgggtac aaaaaactaa
    11881 gccctcctaa aaaaggacat ccaattattt gttcccacta tcaaattgac agtttattta
    11941 agaatacctt gccgcatatt tattaactcc ttttaaatag atacttaaat aatagcacgt
    12001 aagagcatat ttgtaaagga atctccaatt ttttatcaaa gagagtacgt gattacaaaa
    12061 tagctgtaat aatgtaccaa tatttgttat tctataatct tccaattact cccgttcttt
    12121 tcaagtacca aatcaaattg agatacctgc gttgctttgg tctgctggtc gatatactcc
    12181 actgtcagcg ataccgtgac ttgattatcc ttacgattgt gaataggatt taccagttct
    12241 tgaaagatgt actcttttcc gattggtttt aatatcccgt cattcacata gtaggaaagt
    12301 tcactggctg tcgctgtagg atagagcttg aagaacgtcg ttaaaaactc attgatttca
    12361 ttggttgtaa tggaatcaac cgtcccctca ctttcaatgg cttttggttt ataacttgat
    12421 ttcttaggta tgttggtaat ggtcggattc ttaaccagta ccatatttcc agaaccatct
    12481 acatagacac tcactatata agcagagtgg acggtctttg tattttctcc ctctgtaatg
    12541 agctggtcta cactgtaggt tacattaaac tcattgtcgc cagttggctc taccgtccat
    12601 atctgaaatc ctcttacaga agacgataca ggaatatctt tgcgtactgt atcaacattg
    12661 agagcttgaa gttcatctgt cagatagcct tttagacttt ccattcgatt atcaatggac
    12721 ttatcggatt gctcccatga atagtagact ttcgcaaagt tctctacaaa attttctaca
    12781 tgatgagtat caacgtattc cttttctatg atagttgttt cgtgaatagt atgagtatct
    12841 atagctgtaa agtgcttgaa tatcgcaaag ctgaaactaa gccctaaaag tacccacaag
    12901 gcaatcacaa cctttttatg aggattgacc ttatagacac gaggtttctt ttcctttggt
    12961 atctgttttt ctttattctg attttttcta aatttcatca ttaaatcttc ctttctcatt
    13021 gtttgattcg tcctgctccc actaaatgct gttgccagta ggggcttgtt aagtcggcat
    13081 aaccgattgg gtcgcctgca tgaaacatac ggttattgcc aaggtatatc ccaacatgag
    13141 taatataaga gccagcgtta taggtagaat gaaagaaaac caaatcgcca gcttgtgctt
    13201 ccgatagtgg gatatgctgg gtcacatcat attgctgttg tgcggttcgt ggtaagttaa
    13261 ttccagcttt tccatacgtc cattgtgtca gtccgctaca atcaaaagaa gtagtcgggg
    13321 aagctccacc gtaaacgtat cgccagccct catatttcag tgcttcgtcc atgatggctt
    13381 gtaccgtatc atcatcaaac tctgttgtga caagatactg cgttaccagt tgcacataaa
    13441 acatattgcc atagttgtat cgccagcccc cattgatagg tatggctatg ggattggggt
    13501 aagacacttt ttcgccacct gaatactctt ttgagaaact ttgagccagt tcaaaggtat
    13561 atttatttcc acgattagcc acatacccta agaaaccacc accataattg taggactgga
    13621 taaccgattc taaatctaca ctgagccttt cgctactggc taataattca ctgaaatact
    13681 tcacaccttg cttaatggat tcttctgtac tcaatgaatt aggtggaaga ccgagggatt
    13741 ccgaggactg cataacatct tccgcagtac cgcccgattc cacctgtata atcgcaagaa
    13801 gtatgttgac atattcttca acgccatatt ctttggcata tttttctacc ataggcttat
    13861 gagccagcac ttctgcggaa acattcacac ctccataatg aatattggaa attccgctgt
    13921 cctgttcatc tgaaaataaa atggcaacaa acagaagcag tgagaagacc atcaagaata
    13981 atccagaacc accaatcact aaagttttca acttcatggt ttcttaccga ctttcttaat
    14041 ggtggcggtt ttgattggtg gtctacttct tgtattttgt agtggtactc tttgaacagt
    14101 agacggacgt tcttttgtga ttggacgttg tgaagttcta tctgctgtag tggttgaagt
    14161 tgctggcttt tgaacggttt tttcttgaac ggtattgcct tggcgttcca cttttggact
    14221 tgaaaaatcg gacttaactg ctggacgctc ttgtttggct tgttgagatt ccttatatga
    14281 agtctgaata ttagactgtt ttgaggtctg ttcatcatga tattgttctt gtcttgtagt
    14341 cggtctttca tgaacagaag aagcaggctg ttttttctgt ttgacctgtt ccatttcaga
    14401 gcgacgcttc gcaatggttt ttcgcctttg ttcctgctgt tccttgcgtc cactggctct
    14461 gtccgctttg gtttgagaaa tactactggt taaatcacgg acattctctt ttactttgga
    14521 ttttccttga tatactgcat atcttgcatt ggtcggcaaa tctttaacct gttctttcaa
    14581 accactagca gtgtctacca ttctgtcttt ggtatcagct actgtaccga tggtttgacc
    14641 gatacgtttt ccaagtgttg atttttcctt tccgtctggt cgggagtgat ctgcttgtgt
    14701 ccttgcagaa ctccccgaac ccgactgtcc ttttttacct gtaacaatgg cagacccagc
    14761 ccctagagta gtcatggaac gtccaagttt ccgctgtaga cggtgcatgt gagcgtgcat
    14821 aagcatacga ggttttctca tcacacgact tcccacactt tgagaatcgt tactctgtag
    14881 agaaaacata ctcattaaat cgcccagctt gaagtagatt cctgcaaagg tcacaatctg
    14941 tagaaaagca atcaaaaaga acggataacc agccgataag gtatagagca tggttgaaat
    15001 actaaatgct gtcgtaataa tcaatgtgat tccagctcgt gtcaaaatgg tattaaagag
    15061 ctttgttatg gctcgttttg acataccatc aaatgatgga atcatgctta aaataaagct
    15121 cacaggcaga aacatagcat agatgataaa aagtacctgc gagaaaatca tgattcctgt
    15181 taataggaat acaaatatgg aaatcccaat attgaagaca aataggaaga agactgtacc
    15241 taaacggtta atggtctttg taatggttag attggtattg cttctgtctt caatttcttc
    15301 cgcaacaatt ttttctctat cttcgccatt gttggaatct gggctggtgg agagcaggct
    15361 ttccacacgg tcaataccga tactttcaat gtctgaactg ttgtattgaa gcagtagcca
    15421 cggttgctga acctgtatgg aaaacaggct atctctgatt aagtccacgc tgtccttgcc
    15481 ttgactatcg gaatggggca tgacaatctt cgtgccaagt gataaactgg cattactgat
    15541 gtctgatgaa aagtcattga tttttttaat gtagtcggga tcgtaggcaa taaaggaagc
    15601 cgataggata aacaccagca caaaattcat aatggcatga attgcctttg tggtttctct
    15661 ctttatcagt cccgtatagg caacataaac cccaagaacc aaaatcaaga gtaagaggaa
    15721 tccaacatag aaaccctctg ttgaaaatcc gtttgcactc acaccagcta aggtctgcat
    15781 attcttacca atggaatctg ctgtagcgga aatgaagtct aaggaatagg cttcctgtac
    15841 taagtaacct gtcgcattgg aaacatacaa actgattgtc caaataaaat tggtaatggc
    15901 atatagtcca tacatgacct gttttccaat cccgtccgac cagttccacg gaagccagcc
    15961 ccagctatta tccacataaa aatccagttg atagttttca agtgggtatc ggctgtattc
    16021 atttgccaca ttgaccgtat catctaccaa gcccgcagct tgaaccaccg ttcccagcat
    16081 ggctaaaaga aaaatggcaa tcacaagtgt gaaagccact gtcattgcca ctttacctag
    16141 acgtttcagc gtccagtttg attttattct gtttactatt gatggtttca catttacacc
    16201 tcttttcgca caggtggtct ggtatcaaag gcatggagca gttcttcaaa tacagggtgg
    16261 aactgtatca caccgacacg accatataaa tcactgataa ggcattgccc gttttccaaa
    16321 tcacgcaatc gcttctgatt gttttcgtcc tctgggtcta caccaaaaaa ggctaaggtc
    16381 tttttaatct cgttaaggtc agtggaacga aatgcaaatt ttaagccgag gttatttttc
    16441 agtttttcat ctaagaggtc gtctgtattt tgggtcacga aatatacccc agcgttcata
    16501 gcacgaccag cccgaaccag cttcatagat agtgtttttc cttgtgctac ctgtaaaaag
    16561 ctccatgctt cgtctaaatc tacaatcttg aaaatgcttc ggtctgtatg gataaagtct
    16621 aaagcaaagg tactaatgac aatcagcata gcaacggata aaagctccat agtggtatat
    16681 tcctcaaagg aagtttcctt gtcgggaagt accaagtccg caacctgtat aatgttcagt
    16741 tgtttttcta agctgataga ctgctccaca taaccattac tgaataataa atgtgcaaag
    16801 tcatagtctg taaaactttc gatatggtcg gctatactgg tacttagtgg cgtattctca
    16861 acccgtaatt cctcaatcac tttcatcaac cctcgtactt cactattggt tactgcacga
    16921 atggcttttc taaggattgg gaagcgttcc ccatcacgag aggaaatccc cgtaaggaat
    16981 gtcagaatat caatagccag tgattcagaa tctttgggat ttttcataat cacataaggg
    17041 tcaagtaagc ctttgttttt ctcatcagaa gtcagagtga cgatattgat ttcatgggaa
    17101 atctctggca aggtttcttt ccatctgcca cgttctgctt ttgggtctac aatcactgct
    17161 tgtgccccat aaagcaccgc ataatagacg ataaggttat tcgcaaagga tttaccacca
    17221 cccagcgaac caacaaaagc cgacgctaac gcattggtta ctgaaccctt aaccccttga
    17281 ctggcaagag caggtttcag atagacattg cgtccagtat ctaagctgta gccaacataa
    17341 atcccctcat tttcccccag catttgagta gcaccaaaac ctaaaccagc gaggaaatca
    17401 gaggtcacgt attgaatata atcattcata taacgcttgc tggcaggtaa aaattcttca
    17461 tgtaagccga gcatatcccc aaatggtcgt accagtttta cgcttaaatc gtcataaaaa
    17521 tctttcactt cattacaacg acgtttgagt tcgtcaagat catttgctga tacccttacc
    17581 acataagaca gcttgtacat agattccttg ctttggtcta aattggtttc cagctcattc
    17641 acactttcca gagcttccgc cacattggag ctggtttcat tatcactttg ccaagcgtgg
    17701 ttatccaagt ctttcagttc tttcttttta ttgcggacag tagatagggc tttacgattc
    17761 gctacaattt ccacattcat tgacgtatca atcgggaatg taaattgctg ttgctggtag
    17821 tagaagattt cagaggacgg gaagtccagt tctccgacaa tgctgttaat ggtaaagtaa
    17881 gctacataga cggtttcatc ttcctgctgg attttcaaat atcgctgttt ttcttccacc
    17941 aaacagcgag taggcttaat caagtcatag tatttaatca gcgtttcatt atccagcttt
    18001 ttctttgata gatggtactc atactcttca taggcagtgc ctgtctgtcc gtaaaggtgt
    18061 tcaatcagat agccgaagtc gtccttatct aacctgcgga ttttgaaacg acgagagatt
    18121 ttattttcta agagcttttc catcttctga aaacgcagga tttcatcatt actcatacta
    18181 acaaaatcgc ccatcagctt atggttcaca tcatagacaa aatcagacaa agcatttttt
    18241 gcttcaacgg taagactttt catagaaaac tcctgatcgt tgagaagcaa cttaaagccg
    18301 ataaagaaac ggtagttcac ttgattttcg ccaatcatgg atattaaagc gtctgtctgt
    18361 tggtcgattt tgtcataggc aaccgctttg agcttgccag tgacttcatt tttggaacgc
    18421 tcttgtgcag aacgtatgct ggattctgta ctgatttgta aagcatgaat tttgccatca
    18481 cgattttgtg cgataagctg tctgaaagaa tcatgcactt gtattttctg ttctggactt
    18541 agaaatgagt aattgtaagg aacaagctca tagtaagcat aacattcccc gtctttattc
    18601 cagacgagat tgttttcaat gtatttaatt ggatatgcca taaaattcac tcctaactgc
    18661 tgtaatggct tcttgtggct ggtttctgcc aagcgttact ttttttcctg cataggtcag
    18721 ctttggtcgc agtgcataag caatgacaga cttcaaaaat ccataaggct ttttaccatc
    18781 aaaagttttt gtagacataa accatgtgaa agccacagga atcccaaagt atttgagaaa
    18841 tgctccctct atcatggaaa gagggggcaa gttgccaagt atcatcactg caaagagtga
    18901 cacgacaaac catgtcattt gcgtaaaggt tatgggaaac ggaagtctaa aatcattgat
    18961 agaatacagt accttttcca cagaccagat actggtatag cttcgtattt tcttcatgta
    19021 atcaatcctt tcataaaaaa taggggtagc tgattgagcc accccgtaaa atagaaaatc
    19081 tgccagtagt aatgtaccga cagatttaat agacgatttc aaaaatccca tgattggttg
    19141 agataaacgt tcctgaaagg tctaaatccc gaccataggc ttgataatca atatagtttt
    19201 gaagactagc tggtacttcg cctaaagcac ccgtttcttc aatgtagtag cgtgccacgt
    19261 catacatatc atcacaatcg gaatgaatga taatatcctc ttgatgttcg cttagttctt
    19321 caatgcttga aaaatgagtg agcagagcag atagctccga ttgtaattct tcgggtaatt
    19381 ccgataccat ttcccatagt cgattgagtt cgccaatgga agtgtattcg tcaaccgtaa
    19441 agggtaactc gtagtcatga atggcgtatt cctcatattc atcattcaag ccgattttct
    19501 ctttgacttc ctcaaagtca atgggaaagg taaaccacgc accgaccaat tcgccctcat
    19561 tgtatttgcc taaattcgca atatagactt gcatatcgtc catatattca cgtcctttct
    19621 ttgtagagat tcaaaaatcc ctaccgcact tcgtttggtg taccattcct ttgcggaaca
    19681 taagaaaacc acttatattc cacaaaagaa cggttttatt taagcaccaa taatgcgatt
    19741 gaatagctct agtaaaatgt cttttactcc agcagcgttg aagactaagc caaccgcaat
    19801 aatcgcaata attaaaaagc caatcagttt gctaaactca cgcttgaagc caagatacaa
    19861 gccaatcaca acgattgcta aaagcaccag tgattgagcg tttgatagaa accagttata
    19921 aaggttttgt ccaaaattca taaaaatgtt ctcctctcta tattcaatga atttgtattt
    19981 gagttatttt tttgttgtta tcacgtcctg ttcttttact gactgttgct tcaaaatctg
    20041 cttgtgtcgg tctgtcagtt tcgcatggtc gagaatgtct tttacaacct gcgtctggtt
    20101 gatttcatca agtttaatcg caacctttaa ggtcggggca acttgatgag atagccagtt
    20161 cagcgtcctt tggaaggagt aaggctctgg ttttgtggtt agttttaatc gttcacgatt
    20221 gttcccaata aaccaagccc attcttcatt cagtttccaa tcagaacgag gtttggaatc
    20281 gtctttatct acaaaacgga tataccgatt gataatttta aaggcggtat gctctggatt
    20341 gtcatagacg agtaaatcac ggactgcata ataggcacgc tcatttttca atcgaatctc
    20401 aaaacggttt tttacttctg cgtcttcaat gggaatatca tttttcttgt actgctcgta
    20461 gtccttttca tagatacaga aataaacttc actttgtaat gaaccgatat agagggtgtt
    20521 tcccatacat tccttttcct ctttgcgtac cagttcgcca ctgcgatagc ttttaaaact
    20581 gcggaagacg gagatacatt cttcctgttg gcacttttca gtgagtacag ggatatttaa
    20641 aatccctgtc ttatcgttaa tggcaaggtc aaggcgtttc atcacaccgc cagccaccaa
    20701 aacgtccata aagaactcat accagcttct ttgttgtgcc agaagatagc tttcaaattg
    20761 tctgcaccca cgacctttca attccaccag aactcctttg tccagttcat gggagcaaag
    20821 gacgaatatg tcgcctaaag cataatgctc tgaataagaa tagaaaccat agtcctcatg
    20881 aagaaaatag gacagtttca gttgtaagat gttttcgacc acctgctgta cgtctgttgt
    20941 cggaaagcga attcttacat aatcaaacag catttcaagg ggagcgtcgg gattgaagcg
    21001 ttccagagct tcccaaaggg actgctgtaa atcctctgat ggcttgactt ttcctgtttc
    21061 aatatcgctt agatactgcc ttgtaatacc agtcgcaaca gctaaacggt tttgagatag
    21121 tccataagcc aagcgttttt cttttaaatg ctgtaaccaa gtttgttcat tcagtaaaaa
    21181 tccctccaat caaaaaggcg tatgtcaact tttaaagccc atttgacata cgctgaaatt
    21241 ttgtaaatcc cttgtaacca aaggattttc taatgttttt ttgactgttt cctgtcgatt
    21301 tgtacccccc tgttagatac ggggggttaa gtgctggcgt ggctattgcc acaccagcca
    21361 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
    21421 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
    21481 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
    21541 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
    21601 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
    21661 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
    21721 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
    21781 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
    21841 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
    21901 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
    21961 gtccgcaaga tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
    22021 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
    22081 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
    22141 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
    22201 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
    22261 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
    22321 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
    22381 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
    22441 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
    22501 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
    22561 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
    22621 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
    22681 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
    22741 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
    22801 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
    22861 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
    22921 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
    22981 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
    23041 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
    23101 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
    23161 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
    23221 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
    23281 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
    23341 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
    23401 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
    23461 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
    23521 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
    23581 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
    23641 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
    23701 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
    23761 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
    23821 ttatgctatt tttagctcaa taatagctct ttttaagttc ttaattgatt cataatccaa
    23881 agatgaagat ggttcatcta aaagaataat ttcattttct gaaattccac tagcagttat
    23941 agcaattaac tgcttctctc caccggacag ttcaaaaata ttcttgtcta acaaatcttt
    24001 actacctaaa acatctgaat aatagtgtat tttatctaaa attaaatttc tttctataca
    24061 tctattttct aattgaaaag ccaattcatc tgtggaattg atacaataaa actgtgtttt
    24121 aggattttga aacactgtag atataaactt ggatcgttct aatatactca tccctaataa
    24181 agatttgtcc ttgtataaaa catctccttt tacatctcca caatcatatt cgggaataat
    24241 gccgtttatt acttttaaca aactactttt ccccgtacct gagtgtcccg ttataacagt
    24301 tacctctccg ggtttgaaat ttagatttac attttctaat atgctttctc catcaaactt
    24361 taatactaaa ttttgtaaac taagcatact taccccttat atataaatag attgcccata
    24421 ccattatcac aaaaaatatg caatcaatgc caccaatgcg tgattcacta atacttgttc
    24481 gcttttgatt aacagctaac ccttttgtca ttgcggatac tgttaaatca tctgccgtct
    24541 tagacaaaca catcaatagt ggcactaatc tatattcaaa taatagaatt ggatttttta
    24601 ttaacttttt aagcgttagt cctctcaaac gcatggcttt ttttatctgg ctataatcaa
    24661 tccttgcggc ataaaagaaa cgaaccatca cagtcaatgg tattgctatt tcatcgggac
    24721 atttcatttt tttcaatgaa taaatacttt cccctacatt tgatgtgagt atggtatatt
    24781 tccccattaa aaatgcggga agtattttct taacaaccat tactaatatc agtaaaatcg
    24841 ctaccaaggg actgtattct aatttcatta aaaatctatc agcaccataa acgaacacaa
    24901 gagtagccat cccaataata gctactcttg tatgttttgt atttattaaa agcactatcg
    24961 gaattacgga tattataagg gcttgcaaga aatactttac ttgaatattg cctaaaacca
    25021 tcacatatga aagaactatt gtcataaaaa gttttgtacg aaaatcaagt ttgattgtca
    25081 tccttaactc cttatgaatc cttatttttc cataccagcc tttttaaaat gtttttttag
    25141 gaaagccata cctatactac aaccaatata tgctcctata attccaccta ttgccattac
    25201 gacaataatc caattcggca ttacactaag catcttatca ataaattctt gtttatatcc
    25261 tcgctctaac atctgcttga catattcatt tcttgatata aaaattggca accaatttcc
    25321 taatgtgcaa agtggagcaa cagaaaatgc taatcttgcc ttattaacat ccgtatattc
    25381 tcctgatttc aaaataactt cagcaataat accagcaata acagcggtca ataatgccca
    25441 aggtccatgt cccatagcaa catatactaa tgcaataagt aatgattgaa taaacaccat
    25501 tcctcttttt ttaatctttg tggaatacag catatttaca ggtcctacta aaactccctg
    25561 tgcaaatgga acaaccggca ttaaaactgg aaccattcct aaaaatgatc caatcatcat
    25621 aaatacaaaa cctaatacag aaaataatcc tatgttgatt aaatccttta cttctaatcg
    25681 tttactcatt ttaaacctcc ctatctcttg tcaatatcaa caatgtaatt taccattgtt
    25741 tcttttatat attttttatg ttgtgaaaaa gaatttcttg cacagagaac ttcagaactt
    25801 aatatcatcg cattgatata attcactaaa aaaccgtcac caaatatatc tgccttaatt
    25861 ccaagctgct tggcgattaa acttagctca ttagtcgtat taagtttcaa ttcttgatac
    25921 aatttttcca aatcctgatt atattttttt gcttgtaaaa ggagtgtata caatctcatc
    25981 aattctgtat cagccagcga cttatcaacc aaaatatcac ccatttgctg atatttatct
    26041 tttcctcgat tgttttttaa atactcattt atcaagttgt ttctataatc attaccatca
    26101 agcattaagt ctttaaacat ttcgtttgta ttaccataat gatgatagac acctcctcta
    26161 ctcattccta cctctgtgat aacatcttcc attgttgtaa gttgaaaccc tttatttaga
    26221 aagcatttct ttgcagcttc tcgaatctct ttttttctaa tttgtccaac tttttgtttt
    26281 tcttctttca aaacaaagac ctcatttcat atcgtaataa aaaccgacac tactgtcgaa
    26341 ttttatttta tcataaatga tagttaatgt caactaactt ttaagtttga ataacaatct
    26401 tctttatagc tttgactttc agcaaatttt attgtaaaat tatctaaaag ttaatagatg
    26461 cttaatgctt gctatctaat tcattctttt gtagcaagca cagtaagtgt acggacactt
    26521 acgaaaaaat tgatgaagca gccctttggg atctgcttct ttttttatca atttttaact
    26581 tgttagggtg taccctaaga cccgaaatac attcaaagga ggatttacct atggcaaata
    26641 gaatgcgaaa tgaaagactt gaaattaaat taactgaaga agaaaaggct ctttttgagg
    26701 agaaaagaaa acttgcgaaa tgcaaaaata tgagccattt cattcgcaag tgcgttttag
    26761 aaaaggaaat atatcaagtg gatttagagc catttagaga tttacagggc ttgctttcca
    26821 acgctacaaa caacataaat cagattgcaa agcgtgtaaa ttcgaccggc ataatctaca
    26881 aagatgatat aaacgatatg aaaaagcaga ttgaacattt ctcaaaagag ttgtggcaga
    26941 tacattcact gcttcttaac agaacttctg gaggtgatta aattttatgg ctattacaaa
    27001 aatacatccc ataaaatcaa cccttaatct tgccatttca tatattgtta atggagaaaa
    27061 aacagacgag caaatcttag taagcactca taaatgccat caggaaactg ctcataccca
    27121 atttttaaga acacgaaatg atgcaggaac aaacggaact gttcttgcca gacaccttat
    27181 tcaatccttt ttaccgggag aaacaagtcc tgaaattgca catcaaatcg gtcttgaact
    27241 atgtaaaaag atattaaagg atgagtacga atttgtctta tctacccata tagataaagg
    27301 gcatatccac aatcatatca tcttcaataa tgtaaatatg gtaactggca agtgctatca
    27361 atccaacaag aaaagctacc accaaatcag gtatcaaagc gataaactat gcaaggataa
    27421 taacctttct gtgattgatg agttctacga gagctataag agaaagtaca aaacaaatgg
    27481 caagtcatgg tatgaaaatg aacaggcaaa gcgtggcagt tcttggaaga gcaagcttca
    27541 atttgacatt gatcgtttga taaaacagtc taaagattgg gaagaatttc taaagaaaat
    27601 ggcggaactt ggttatgaaa taaagcatgg aaaacatata gcctttaagc caaaagataa
    27661 gcagaaattt acaagggcta agacgattgg tgaggattat accgaagaaa gattaagaga
    27721 gcgtattaca gaaaatcaat caattaaagc cccacctgtc aaaaaacgca ttggaaatgt
    27781 catcaatatg aataccaatg ccaaagtgaa agagagcaaa ggctatgaat attgggcaac
    27841 aaaacataac ttaaatacaa tggctgagtc agttgttttc atcagagaac atggcattaa
    27901 atccgttaag cagcttgatg aatgcatcaa gaaaagtgct gaagaaagac agaacttaca
    27961 agataaaatc aaaaaaattg acaaggatat gcaactactt tctgatacga tggaacaagt
    28021 tcatactgtt aaaaagtatc gagcctacta caaggaatat aaagcaaatc cttctgataa
    28081 ggcatttttt gaggagcata agtctgaaat cacacgctac gaaacagatc ttgcaaaact
    28141 caaaaaatcc tattcaaagc tgcctgattc aaaagatatt ttagataaac ttgataaatt
    28201 gcaagaaaaa aagaataccc taatgcaaga gtattcttct acaaaatcta ctatggacga
    28261 gctttatcaa atacgaaaga actatgggat ttacatgggc aaggagatgg agagataatt
    28321 ttttctctcc tcttttttca agacaaataa aaaacagtcg gtgcagccct aagaccacac
    28381 cgaccgtaaa tttatctctc agcttctttg tttgcttctt tcttttcttt tggcttttcc
    28441 ttatcttccg cctgatattt cttgatagct ccaagtacag attctttctt ttcttcttgt
    28501 cctttcattt gttcctttgc ctttagtagc tttgaagaaa gtatcctgat gttgctatgc
    28561 tccttgccgt tatcatcaat ggatgttctg atttgtccaa agagcttaac aaaatctccc
    28621 tgcttaaagt cctttggaat atcgcttttt tctccgtatg ccgaacaatt atgatatacc
    28681 ttattccctt catcgtcttt ggatactacg gagaaattcg ctaccttaaa ggcttctccg
    28741 tttttatttt ccctttcaac tacatcgacc tctccaacga tatttcctac aatatttaca
    28801 aggttatcct tttcttcctg aacataaggc aggtctttta tctgcccctg ttctcttaaa
    28861 tcctcaatca tatagtcaaa ttcctcatgc agcaaattaa ggctgtcatt gtccatataa
    28921 gcgtcataga gcttatctaa agcactttca ttgttgatac ctttttctag gcttataatc
    28981 gcctttacaa agtccttgtg gttatcattt accatatctt ctatttgatt tctcattgtt
    29041 ttgtaatcca tgtttttatc tcctttcatg gcaaaaggga ggttaccctc cccttatctt
    29101 aaaaattcct gttcttttgt tttttgcttt tcttcagttt tgctttcatt ttgataagct
    29161 cttatctgtc ctaaaataga tggcttatcc tcagattttt gtgcggtttc ttctttgcta
    29221 tgaagattgt cctccacatc ataagttgac tcaaaataat cactgtcctt aaagtcattg
    29281 tcatatctgt caggaatacc gtcattatcg aggtctttgg aaagcggatc atagaagttg
    29341 ccttcatcat caatttcaag ccctgttgct gcttttaaat cttcagaatc aacatagact
    29401 aaatcactaa aagaggacat ttccatttca tttttcatat tccttagagc ttcattttct
    29461 cctttactct cgtaatcaaa gctctctgtt ttgataggag tatcatcaat gtactgtgtc
    29521 caagttttct cctctaagtt cagttcatac tgaatcccat gcctttcatc tggtgtattg
    29581 gtataggcga tcccgatatg ctttaagtca ggatacaagg tattaaattc atcatagctg
    29641 tgattttctt cgtactctct gttacagaag tcaatgattg ccctttttac atcttctaca
    29701 agtggattgt catttctctt ttcttccact tctcccatat caaggagctt attcagttct
    29761 gcaagtctta ataccttagt tttcagctca tcagcttttt caaaaggctt tttgagttct
    29821 tctttggcat tttcaagttg ttcctttgtg ctgataagtt tttcttcaag cctatttaat
    29881 ttctcaggca ttttctcaag agcgttatca agtcttgtaa tgttaccgtc cacacttgtt
    29941 ccaagctctc ctgaatgctt tgcagcaccg tttaagctaa agttatgctc attggtaaag
    30001 aagttatagc ttacctctaa atccatattt ctataccttc ctataacctt gctttcattg
    30061 attttaacct ttgaaattgc ttcaagcagt ctttctccgg ctaatttctt atcggtaatc
    30121 ttttctcctg caatagtaat agaagtaaac ttttcctcac cttccgcttt aggttctaca
    30181 cttgctatat ctttcttaac agcttctatg agcttttccg ttcttgcgat ttcttcagga
    30241 tagtttttcg ccactttatc ctctaatctg taacggttag acttatagtt tgcttcaagc
    30301 attttaagtt ttgtaacctc gttgtccaaa tccatcttct ctttaatctt tggatcaccc
    30361 gttgcaagag ctttaatctc tgcatagtta agagagcttt cgtccacatc ttccgcaaca
    30421 cgaacaggag tctttgaagt cataatctga gaaatgaatt tctgcttatt ctctatcgtc
    30481 tgccataagt agctgtcaaa tgtattctct gtaacataac gatagatatt tactttctca
    30541 ttttcgtttc cctgtcttac aattctccct gctctttgct ctaagtcagc aggtctccat
    30601 ggtacgtcta aatcatgcat tgcaattagt ttattttgca catttgtacc agcacccatc
    30661 ttctgtgtcg aacccattaa gatacgaact tcgccttttc ttacctttgc aaagagttca
    30721 tctttttgct tatcggaatt cgcttcatgg ataaaggcga tttcttcttt cggtattccc
    30781 atagatacga gcttttctct aatatcatca tagatgttaa attctccatc tccttttgga
    30841 gtagacatat cggaaaaaag tagctgtgtt gacctgtttt cttttgtctt atcccaaata
    30901 gcaaatacat ttttcacgca tacattgacc ttgctatcag gattatcagg aagaagtgga
    30961 ttgattaaac gctgatctaa ggcaagtttc ttaccatcgt tggtaatctt aagcatatta
    31021 tcaacatctg gctctacaac cctatttctg acatcatctg ctctttcaga gaggctcttt
    31081 agaatttcct tttgttcctc acttggctct gtcttaataa cctcgtagtt agcttcaggt
    31141 gtaggaagat taagcatatc tgccgtctga atatcagcaa cttccttaaa catagacata
    31201 agctcaggca agttatagaa ctttgaaaat ctcgttttca ccctatatcc tgtaccttca
    31261 ggcgataatt caaaggagga ttgtgtttct ccaaaagtgg aagcccaaga gtcaaaatgc
    31321 tccagattat ttttctttaa gctctcatac tgaagataac gctgcatggt ataaagctcg
    31381 gtcattgagt tacttacagg cgttcctgtg gcaaagacca cgcctttgcc gcctgtcatt
    31441 tcgtccatat atctgcattt cataaacata tcggaggact taaaggcttc tgactgccct
    31501 atacctgcaa catttctcat tttggtatag agataaaggt ttttaaagcc atgtgcttcg
    31561 tcaacaaaga gcttatcaac tcccagctcc tcaaaggtaa tcacatcgtc tttcttaaaa
    31621 tcatcattta atttttcaag ccttgtttcc agttttttct ttgtcttttc aagctgtttt
    31681 acggtaaagt tctgatttct atcatgcttg tattcttcta catagtttac gatttcatca
    31741 atctgatctt gaatatgctt ttcctgatat tccttactca tcgggatttt ttcaaactgc
    31801 gtatgtccga taacaaccgc atcatattcc cctgtggcaa tcttaccaat aaatctcttt
    31861 ctgtttttcg gctcaaaatc tttcttatca gccaccataa tgttagccga tggatatagc
    31921 tgcataaact cacgcccgat ttgccctgtt aaatgatttg gtacaacaaa caaggactta
    31981 ctgcacattc caagcctttt actctccatt gcggaagcta ccatttcaaa ggtctttcca
    32041 cttcctacta catgggcaag caaggtattt cctccataaa ggcttcttgc tatggcattt
    32101 ctttgatgag gtcttaagtc aatctctgta ttcattccct caaaagagag attgcttccg
    32161 tcatattctc tgttgcggat tgagttaaaa cgctcattat acagttttac aagacggttt
    32221 cttctttcct gatcgttaaa tatccagttc ttaaattctt cttttaataa ctcctgcttt
    32281 tgtcctgcaa gcatggtttc ttttttattt aagacagaag ttttagagcc atccggattt
    32341 acaatctggt caaatacctt tgtttctttt aggtttaagg catcttcaat cagcttatag
    32401 gcattaactc tatttgtacc aaaggtcatt tctgcaaggt catttcctct gtccttgctt
    32461 tttccttcta cattccattc gcttgtaagg ttggaaaatt ttaccttaat atcccatttg
    32521 gcatatcccg gagtttttag cgtttcaaaa ataaatttct caatatcttt aataggtatc
    32581 caagttgcac caagacgcac attgatttca cttgcttcca attcctttgg aagaactttt
    32641 gtaagctctg ttttttgata ttccaaacgg ttcatttcat agcttatcag ctctttttct
    32701 ttgccatttt cttcatagcc aagatgagga agttctcttt ccgtttgtct tagctttgat
    32761 aagtagctgt ctactatgac aatcttatcc ctgatatttc cactcaaata ttcatctttt
    32821 gttacatagc catatttata tgaattactg ccattagcac aggcaaaagg taaatcgcca
    32881 tcttctaagt taaaggaaag tggtctgtaa aagttttgtt cttctctgat gtttagatag
    32941 atttcccctc gaagctcctc aattaaagtt ggtctgtctt ttccggtaag acttcccata
    33001 tagtcaaagt ccacatatcc tttttcagat accgataaaa caagagcttc taaagaggta
    33061 tccacatggt ctatgatttt ggcttttgta atggttcttt tggagaaaat atctcccttt
    33121 gccttgaaat tttcttcttc atcaaggatt tctatggagg aaacaagcgg gaagttgcta
    33181 tcctctttta aggctctggt attgcttagg ttattgacaa agccatgctt tttagaaaag
    33241 ttgtcatata cttcatttag tttttcctgt gaagccttga tttcttcttc gttaaaatct
    33301 tctttctgct tgtaaatcac atcttttaag gcagcattca gctcaaggta atccttgatt
    33361 ttttctttat tcttgtctga tacttccttt ttgataaaaa gtgagttttc tctgtaatag
    33421 acttcatcgt caatcaaggt ataagagaag ttctttacat catcggttgc agggatagaa
    33481 gttatttcat catcaagtag ctctatttct tcatacttgg cttcttttga aattctttct
    33541 cctgcaatct cgatacgctc ctttaatgaa gccatgttta tctctgtacc taaataagct
    33601 atcggctcac aagtgagtgt tttcccaaac cttccgctaa cttcacgcat agaaccaagc
    33661 acctgctcag gatgatcgac aaagtatttg ttatatgaaa gtccattttc atcttccgca
    33721 aggtgtatcc aatcttcatc tcgctctaat acactatctc ttttctttaa gaagataata
    33781 tccgaagtta cttctgtgcc ggcaacaccc ttaaaggtat cgtttggaag tctgattgct
    33841 cctataaatt cggttcttgc tgcaagatat cttcttacac tttcgtcttt tttatccatt
    33901 gttcctgaag atgtaataaa ggcgataaca ccgccgtttc ttaccttatc aatggacttg
    33961 gcaaagaaat aatcgtggat aagaaagtta ttacgattgt attccctgtc atttacctta
    34021 tactctccaa atggaacatt tccgattgct acatcgaaga agttattgga aaatcccgtt
    34081 tcttcaagtc cctttacctg tatatcactt tcagggtata gcagctttcc aatacgaccg
    34141 cttaccgaat caagctctac tccataaaac tttgactgat tcatttcatc aggtaaatta
    34201 ccgataaagt tcccgatacc cattgacggt tcaaggatat ttccctgttt aaatcccata
    34261 cctgaaagcg tcttatatac gccatctata acggttttcg gtgtgtaaaa gctcgttaag
    34321 gttgattctc ttgcagcttc atattctgat gacgatagat tttcctttaa gaaggctctt
    34381 gcctctttcc actgtccatc cttactttca tcaaagacat cagcaagtcc accccaacca
    34441 acatatttcg ctaaaacttc ctgagctgta atatcaagct ctcgttctcc actttccacc
    34501 ctgttgagca tagagattgc ttcaaggtta ttgtttaacc tctcacttgg aaataacttt
    34561 gaaggaagcg tttcttctgt aatcttgaaa ttgtgagcct gatttttctt tatctctgct
    34621 tcctcaaaag tcttttcagg tttcgcataa gtcaaatttt caaagatttt accaatctca
    34681 ctttccttac gataaggaat aacatcggag cctgtaatca tgcctccaag atattcggta
    34741 ttatccttaa tcgttactgt ctttaggtta tttcccatat catcaaatct tgtgatggta
    34801 tagtcttttc ccttatattt cacttcatca cctatgataa agtcaggtct ttcaagactt
    34861 acttgtctta ataaatcctc attatcagta aaggctacaa tcggtatttg atgattacct
    34921 tgccttgcag gatcaagcca caaatcattt cttcctgtga ttggattttt ggaaatctct
    34981 cttactttgt actcctcatg attaaaatag acggtatcat cttctttaac tgcaaactca
    35041 tctgaagatc tgtcctcttt ttcattaagc tctacttctt ctttttcctt tagataatct
    35101 aataaggtag cctgaaaagg ttctgcctgt atgctttctt ctacttcttc aggtgcttca
    35161 aggtctgcaa tattctcctc aaagctaagt tctccgttaa atacattgtg aagctcctgc
    35221 tcatccatct gctttttaag ctcactgtct ctaagttctc taaaggtctt tggaaaatcc
    35281 tctaaaatga gcctttgtgc atttagttcc tttagctctt caagattaaa atatccccat
    35341 tcaggctcta ttccaagcac aagtccaaaa gcgtctttac tttccctgtc atattccgtc
    35401 atataccaag tccagttact tctaaatgga atgatatatg ctgcatgaac ctgtttatcc
    35461 gctaaagcta catcctcttg tgcataaagt tcaggaactt tctcaagcat ttcatcagtc
    35521 attagattat atggatcgcc tttagagtaa taacttggct ctttttgttc ttctatcgct
    35581 gtcttgcttt caattttatt ctcttcaaga taaatatttt tagaaagcag ctcatctata
    35641 tgctttgcta catttgacca tgtaagaaaa acatcgttac aatgattctt ctgtaatttc
    35701 agtccctttg catcatgcca ttcatcactt ccctttgctc ctgaaacagc atgagaacct
    35761 ccaccgattc catactcatc ttttaagaaa ttcgcttttt cctgcaaggt atgattttct
    35821 ttgaaaaact taataattcg ctcttttcct ctatcaaagc cgcttcctct tgaaatcgta
    35881 gcaaggactt catcttctgt aataaagcct tgtacctttg gaggttcgat aaggttagaa
    35941 gtatattcct ttcttgtaag ttcaagctcc tgcaattttt gataaaggct atctaccttg
    36001 tgataatgaa accttagtac atctctattt tctttgtatc ctgctaaaaa acggctgtac
    36061 tcggaaataa cattttttag atagtcagga tttttaagag cttccgataa ctgtcttgtt
    36121 tctttaggaa actcacctcc tctttccata aagtcaaaat atccctgtgc tttcccttct
    36181 tcacttaaat cgtgatataa ataccataag gattctgaaa ctctatctct ttcatagtca
    36241 tgtgcttcca aaagctctac atttgtggca aactctccat tttccaaaag ctcattgatt
    36301 cttcttacag catcactcca gcttaaaatt tgcgtcatat cttctcttgc agaagttcca
    36361 taagctaaat gaataccttt atccgaatac caggaagata cttctgctcc attaagaaat
    36421 aaaccgtttc cgcctctaaa ggtatcttta aggtattctc ctaattcttc tactgttttc
    36481 cctttggaaa attcagcaat gataggaagt ctttcgccct catggtttcc accgtttaca
    36541 agaatactgt caatatcatt ttgtgtaaga ggtattgtaa gtttaatctg tcctgatctg
    36601 ttttcgggta aagaaaaaga agccttgtca gcttctctta tctctttatc cgtattttct
    36661 tttagatttc cactatttcc ttgattgtca tctctttgag ggctgaaatc atcgctttgt
    36721 actgcggatg gctctcgtcc tctatctccc aagctgccat cagtttcggc ttctctgctc
    36781 tcataaattc tattgcttgt ttctgcgtat ccatcagatg ccctatcagt ttcttctcct
    36841 tgtatagatc cactaacatc tcgaagttgc tctgctcctc gctgtttgaa agataatcca
    36901 gtctcatcac tgcgtatgtc ggattcggat attccctcat aaagtccatc tcttcctcca
    36961 actgattcag tgtattctct ttgattttct ctattatctc gtccgtactc tccatttcgg
    37021 aaaattcgct cgttttcact aattctttcc tgatcatctc gtcgaagtac attttcttct
    37081 acctcctcta atttttcttt tattttatta tatcctgctt ctttacctct taaaacttct
    37141 ttttgaagct ctaattcttt gcttttttga atggttgcat caatgactgt tccgctaata
    37201 tccgatacag tttctccaag gctcataaga gaaatgctgt caagcattgc aaagttttcc
    37261 tttaacagct ccttatccat tggatagtct aacttaaatc ttgaagctac tgcataactt
    37321 accgagtccc ttgcaaactt ggtaaaggat attctgtcct catcagatat tctaagttca
    37381 ttcatcaagc tatctatttt ttcatctccg taaagcctac ttaaagaaaa gatattttct
    37441 aaggtgcttt cactttcttc atagccttca gcttttatca tttcttttaa tacatctcta
    37501 tgagcttctt tatcaaatct ccaaagattt acctcattga catctctgtt tttggaaact
    37561 gtctgactaa tatcaaagat atagtccacc tttttgtatg tgccatagtc ctctaaaatg
    37621 ggaataccct tttgacctcg catgacagtt cggttaaagt gttctctcca gtagtcaaac
    37681 ttggcacaag ctgtcgcttc aggattttta tcataaatac ttaactgact tctaaaatcg
    37741 tacttctgat tgttcccgac aacttttaag agcttcagat actctgcttc actctgcaga
    37801 acatcttgtt ttatcagctc caaaatgtta tgaaaatcat ttattcgcat gtttacctcc
    37861 ttcttttttt acaaacaaaa aaggcggtta gattttactc taatcacctt taaattctgt
    37921 gtgctacaac ttactgctat tcattcagtt cccaatgacc attacttcca cttcctacat
    37981 attgtagatt atccatttct ttaatggttc tttctatagt ctttacacta actccagctt
    38041 catctgcaat tgcttttctt gtaatcttgt tgtttcctct tattttttct tttataaact
    38101 ctgcaagagc tatcttatcg tgagcgacat cctgagcgac actgtgagcg acatcctgag
    38161 cgacaccgct tcctccaact ttttgagtcg ctattttctt caaaggaata atcgttctaa
    38221 atatatctcc ctcctcaaac agaggatcaa cacctgaata tagccttgta tatttatagg
    38281 tgtttctcat acctgaacca agctcatcag caagtcctat ttctctaaat acttttgaaa
    38341 tagccggatt tttaggaaaa ggttcaaact tttgtaaatc caatgctccc atgccatgag
    38401 ctaagttact gttttcaatc ataatcttct catcgtcaat aatcattttt gcagggaaac
    38461 cacttgaata atctctgtga gccaatgtat tagaaacaat ttctctaagt attctatccc
    38521 ttgcattgac atttacaatt ccgtctaaga caaataagtc attcaaatgc ttctgtccaa
    38581 acgcaataag cctatcgtag ctatcaatca gatttgttat gacaacatct ctatcgtcat
    38641 acctatcctt gttttcaact ctaaatattg catcagtttt atgctgtggg agaactgaca
    38701 taatagagtt gtcttttcca aataacaaaa ttgccgctaa tgtaatgccc tcatgctttg
    38761 tttcaggatc tgtcagaatg agatttgcac ttcggagcag ttcctcataa ctcatatttt
    38821 cccagacatg atttttattt cttgctactg ccattctctt ggctttatca ataacatcag
    38881 tatcaagaaa ttctatatcg aggtttggat acaccttatt cacaaaatag cttccctgtt
    38941 tcctcgcata tagcttataa acaagttctg catggtctgt gatattgatg tctccttcat
    39001 aagacctgtc ccatattctt ccgttatgcc tgcatacctg ataaccttca ggtactcgga
    39061 tataaatcac ttttttactg tcaagctcaa atacttccgg taataaataa agtggtgggt
    39121 acatcttctg cgaattgttg atagatgttg taaattcttt aataatcttg tcaactttat
    39181 cttcactaac accaacaata tctcttttat catttacacc aagtaaaata tgtcctccat
    39241 ttctattgtt gaaagagcat actgtatcaa agacatcttt ggttagagca ttcctcgatt
    39301 ctttaaattc aacatctatc ttttctccat tttgaattaa cttttttatt tcatctatag
    39361 tcatctttgt tgtttcacca cctttattta tcaatgtttt cttcaataaa agtcttggag
    39421 ttttgaattt gcactttatc tttattgact acaaaagtaa cataatctcc attttgtaag
    39481 tccaaaagtt ctcttatcct ttttggaata gtaacctgcc cttttgacat aacttttgca
    39541 gtatccataa atgtatcttt catacctgtt tcctttctcc ctacttttcc tacaaaagat
    39601 tatatcattt ttagggcatt ttttccacct tgaaattagt ggcatcttac ttggtataag
    39661 tggaaaccac ttcttttatc tcattttcaa tcgcttctaa aaagttttcc tctgaagatt
    39721 gcccctgtgc aatatccgat aactccattt cccactttgc tgttgtttct gctgatttaa
    39781 aagtatcggc tacaatcgtt acaaggctga ttcccttatg tgtagcaata aggttctttt
    39841 tatctctttc tacaaatccc ttgaaaatca gattttcaat aatccctgct cttgttgcag
    39901 gtgttccaag tccttttcgc tcaacttcta cacctttttc caatgcgtca tttcctgcaa
    39961 gctccatcgc ctttaggaga agatcttccg taaaatgctt agctggttga gtgtattttt
    40021 cttttatctc tttatcttta atatcaagac tataaccaat ctttacatcc ggaagcactg
    40081 tatcttcatt tttctttttc gcatattcgt ttaggtattt ggtaaagcca tcatctacaa
    40141 tcacctttcc actacttgta aattcaaatc catcaaattc agccacaatc ttcgttgtat
    40201 tctcaattaa aggatagcct acacttgcat gtagcttatt taaaataagt tcatatacct
    40261 tcaattcact ttccggaaga gaagttaagt tctcattcat actgcttgct gtcggtataa
    40321 tcgcatgatg gtctgtaacc tttttagaat taaataccgt cttgatacgc tctgtgtcaa
    40381 aatcattctt tcctaaaatg ttattaaccg tacttacaat catatcttcc gtaaggcatc
    40441 tgctgtctgt tcttggatag gtaatcagtt tcttttcgta aagactttga gcataatcaa
    40501 gtgtctgctt agctgagtat ccaaaatatt tattgcactc tctttgaagc gtcgtcaggt
    40561 caaatggcag ctcaggcttt gttatctttt ccttttgaat aacatcggta atttctatct
    40621 tatcgcctac taaatttaag agctgttccg ctgttatttc atcatcaatt ctatctgttg
    40681 atagtgtaaa gccattaagg cttaattcca ctgtaaaata tttttctttc ttgaaattgg
    40741 ctatctcacc atctcttttt acaatcattg caagggtagg tgtctgcact ctgcccacac
    40801 tgtaattttg cttgtataga cacgaataca gtctgcttaa attcattccc acaagccaat
    40861 ctgctattgc tcttgcttgt gcagactcaa atagattatc gtaagaactt ccatctttta
    40921 ggttatcaaa gccctctttt atggcactat cttccattga tgaaatccaa agacgcttca
    40981 ttctcttttt acaatttgcc tgattatata caagcctgaa gatggcttct ccttcacgcc
    41041 ctgcatcgca ggcatttatc acgatgtcta tatccttatc attcatcagc tttttaagaa
    41101 tcgtaaattg tttctttgta gactttgcaa tctcatactt atattccttt ggaataatcg
    41161 gtaaatccgc catattccac ttagcatact tttcatcata gctttccgga tttgccattt
    41221 taattaaatg tccaacacac cagcttacct tatatccgtt tccttcataa tatccgtctt
    41281 tcttctttgt tgctccgatc acttttgcaa tagaaattgc aacacttggc ttttcagcaa
    41341 ttactaaatt catctatttt ttcctcctgt ttttcaaaat aatagggcgg aagatgttac
    41401 tctcccgccc tgtcttttgc accaaatatt gtatagtttt gggtgcaaat ttattccaat
    41461 tcatcttctt tatcttctgt ttctgtttca tctacttcat tttcactttc ttctgcctct
    41521 gaaaagaaat catcatcttc ctcctcaaag ccttcaagct ccttatcttc ttttttctta
    41581 acgaccttga aataatatcc tgcacctaat gctcctgcta ctacaagaat gagaattaag
    41641 taggttccca tattgctgct ttcttctttt tttactggct taggttcttc tttttcaggt
    41701 tcttcctttg taatttcctg ttttggagct tctttctttt caaccatatt aagaagatca
    41761 tcttcggata cttctgttag gagcatgaca ttttcgctat cctcatcgtg attgatgatt
    41821 aaatgaaagg tcttgccatt cttagtagta aaggtaacaa actgtcttgc atccgctgaa
    41881 tacatatccg tttctttatt atctttactg tcattatggt gtattggata atccttgttc
    41941 gcattatcct tattttccgt aacagttcct cttgcctttg atggtgctga cgcaactcct
    42001 ttattggtat ttacattctt acttgaacca tccatagagg aatcctgact gctgttattg
    42061 gcaggctgtt tcggtgtcag cttattggga taacgaactt ctttttcttt gtcattattc
    42121 ttaccaatat ttgtgtcctt tgtaatcttt cctgtattat cctgtgatga tgagccttta
    42181 cccgtatcac ttacagatgt ttgaggaaag tttcctgttc ctgttttcat tccggagata
    42241 gggctgattg gtgttacagt aggattatgc gtaactgtag ccttgccaac ctcattcgtc
    42301 tttttctcaa gctccttaat tttctcagtt agcttctcaa tctccttttt aatatccgcc
    42361 gataaatcct tatcgtcttt gcccttttca agtttttcct tcagcttatc tattttttcc
    42421 tcaaggtctt tgattttctc cttttgcttg tcgcttaatt tatccttgtc cttaatctcc
    42481 tgatttagct tatcaagttt ttcctgaagt tccttagatt ccttttccat tttggaaatg
    42541 tcatctttgc taagctctgt ttgaattccc ttatcttcag tttttggctt ttctgtctgc
    42601 gtctgagcat tactttctaa cttctttaca attcggataa tactatcgct tccatcacct
    42661 tttactgtgt agcttacaaa atcgtcatta aaactcatat tatccggaag catttcaaga
    42721 tcagacgcat caatcatctg atttttgtca aaggaagctg aatactcctt atatacattt
    42781 ccgtcctgat attgatattt gatctttact tcactttttg tctgactttc ctcatcctta
    42841 gtatccttat tgtctgtttg agctgacgca ttcgctaccc tcttatataa atcctctaaa
    42901 ggtaattcaa ggtagggtac accagtatga aatctattcc atgtttcaat aatcagcttg
    42961 tccttaacaa tcttaatttc ttttacattg ttgatattgg gatttgcttc ttttactctg
    43021 ccaataatag aattctttgt ttcctcttta aactctccct catagtcaac agttactttc
    43081 tcaatatttc tatttaactg tagaacaggg caggtataga caatgacatt tgctttcttt
    43141 ccttttacgg ttcgttcttc tgcattttct gtaatatctc caatatagta attatcctta
    43201 tctcttggag aaacgatact tgtaaaagca cctgtcccta tattatgaat tcgataatat
    43261 ggatagggtt tctttgtcat atatcttaga tcatctaact gatttacctt gtccatattc
    43321 tcattggtaa aggtttcatt atacttatcg acaactacac cgcccttttc ttcaaaggat
    43381 tttgataagg aaaatttaaa gttcaatggc tgaccttcct tatttccttt tccgagatga
    43441 taaaatcctc taaaggtgtc atctgaagta tgatcctcaa atttcagttc ataatatgtt
    43501 tcatattttt caggcggttc atttgatgca aatactgtct ttgcaccaac ttttaacacc
    43561 cctaaaactc caaccattag cagggtaaaa gctacaacaa tggctgtaat tcttttattt
    43621 ttcaaactgg ttttcatttg ttttctcctt tttcacttct gctttttctc tgtttacttt
    43681 tgccattaaa tcactgattg taatgttgtt ctttctgcaa atggcaataa tttcttcgtt
    43741 ttcaagttct tcctcacgaa tgaacaaagg ctccaattct tcatcaatca gagccttttt
    43801 atcttttaat ttctttattc tgttttttac tgctgtaagt tcttttttca aattgtgtcc
    43861 tccttatctg tttacatttg gcggaaagcc gaagcctact ggatgatgct gacaaaaaga
    43921 tgctatccaa tcatctaaag ttgttactct gattcgaccg atattatcta ttactttgcc
    43981 atcgcctata taaatgccta catgaccata agtaagtcct gctgtacttc cgctgctact
    44041 actttccacc gcaacaagca ttcccacctt gagttttgat ttgtccgatg taaaggtgta
    44101 gtttcgatac atatcacagg catttccgcc aatatatcca agtcctgcat tttgatagac
    44161 ctgtgatacc cacatggcac accagcctgc ccccggagat ggcgtaatgt atgcagcatt
    44221 tacaatcttc ttttgaactt ccgtagaagc ctcatactct tttccgcctc cgatacctcc
    44281 attggaagca ataaggtcgc tattaccaaa ggcttctccc atattgcctt gagcaaggaa
    44341 tagggcttca tagtgcttca gattgtcagg atagtttgca aaaacctttc tgataatgct
    44401 atccatctct tttttatgaa gcgttacaat cagtttcttg tactcgtaag gttcttcatg
    44461 gctttcggta tattcatttc catcttcatc ggtataagtt tctgtaactg tcctatatct
    44521 gatttccact tcttccttat actcaaggtc atacatggac ttaaaaagct catttaatac
    44581 ggagcttact tccgatgcat tctttacttc cccgcacctt gatgtaatgt aggataaaag
    44641 ctcgtggaca ttatgaccga tgtactctgt gttatttagg atgtactcat catatccggg
    44701 ataattttct tctacattgt caacctcact ttgaagctcc ttttccatct ccgaaaaatt
    44761 ctcattgatt tcacttagga catttggctt tgacaaatag cttgttgtaa gaacagaact
    44821 tgtggagttc ataaagcctg tcattcctgt tcctgcaaag ttgataaaga aagttcccaa
    44881 aataataaga cctatgaaaa taatcataag tcccttcgct tttcttaata taacttcctt
    44941 tgaactttta agacttccta taagcccttc cttaatgcga tctctaagcc ttgacttatt
    45001 cttcctttta atggaatctt tcatctgctt tcgcttctga aatcgcttaa agttatttgc
    45061 tttttgatac tcctgtgtct ttttcagctc ctctttggca tctcgaaact caagtttgga
    45121 ttttctcttt ctgattttat agtccttatt cgtaaggtca tatccttttt ttgctttttt
    45181 cttatccgag tagttcttaa tgccatgaat gagctttgag cttgtatctg ctgtcttctc
    45241 tcctgcctct accccttgat tttcatcgct tccatgagat aggtaatctc ttacggtttc
    45301 acttccttta gcaagtcctg ataaagcgga cactttagaa gtcttattct taaaggctct
    45361 ttcctgttct ttagaaagcc tgtttttctt ttctctatca agaatggctt cttttccgct
    45421 ttttttacta tccgcctttt cctctttggc ttctttatcc ttttttctgg tatagagctt
    45481 atcagaatag ttttttctct tataattttt cttttgagct ttttggcttt ttgaaaagcc
    45541 ttttgtatct tctactttat gttgcagatt atcctctaca tcataggttg actcaaaata
    45601 gtcgctgtcc ctaaagtcat tgtcatatct gtctatgatt ccgtcattgt cgaggtcttt
    45661 tcctaaagga tcatagattt ttccatcctt aacctcagta tcataatccg ctttcccgat
    45721 ttcttcctga cttacacttc ctgtttcagg acttctatac cttgcatttc ttttagaagt
    45781 ttttccgttt aattcagttt ctgcacttct cttactgacc ttttcatgaa ccttatcttg
    45841 aaatctgtct ttgtcatgga cgattttccc tctgtaatca tcgttatgct ttagcttatt
    45901 ttcttcaggc tctatgctgc tattactttg cagcctttcc ttttcaatcc ttgccctttg
    45961 cctttcctta aagtcctttt tcagtttctt tcccataagc ctacctcact tcttcaggct
    46021 tggttgtcat tttctgataa aggattgtgt ctttcgggaa tttatcaagg aaagggacaa
    46081 tggtatttcc aaagaacaaa agtccttctc ctgcattgga attggttaca tattttagct
    46141 gtggctgtga gattttaagt ttccttgcta aaatctctct atctcctgaa gcctgattaa
    46201 gcattaaaac aaagtccgta ttatcaaaga tattttcaat ttccttgctc ataagtaagt
    46261 ctttgacatt ttgtgtaatg cctgtcggga ttcctcccca cttacgaaat cttttccaaa
    46321 tttctacgga ataggaagct gtctgctcat cttttaacaa taagtgaaac tcgtcgatat
    46381 agtaccttgt agccttattt cctctgtttt gcgatacctt attccacacc tgatcctgaa
    46441 taacaagcat tccgattttt ttaagctgtg agcctaactc cttaatatca aaacaaagta
    46501 gctgcttatt taagtccaca ttggactgat ggttaaatac atttaaggat cctgttacat
    46561 aaatctccat ttccgttgcc agctttttac cgactttttc ttcctgattt ttgagcatat
    46621 catacaggtt ttgaagaatc ggcatattac aaggctttgg attttcaaaa tacttttcat
    46681 aaatcttagg aaggcatctg tctataaccg acttttcttc tgctgtaaga ccactaccgc
    46741 caactactaa ttcaagcatc gacataatga agtttgcttt atctttcagt ggtgcgtccc
    46801 catcgccata gttcatattt atatctaaag gattaaggta gtcttttgac ttactgctga
    46861 cctttattac ttctccttta aactgacgaa caaggtttcc gtactcgcct tccggatcgc
    46921 agataataac gtcatcatcc gttgtaagaa tggcatttgc catttctctt tttgcactaa
    46981 aggatttacc acttcccgga gttccgagaa ttaaaccgtt cgggtttttc aatttctttc
    47041 tatcagccat aatcaggtta tggcttaggg catttagtcc ataatacaaa ctgttcgccg
    47101 aatttatgaa aagctcctct gtggtaaaag gcataaatac tgccgtagat gatgaggtta
    47161 gtcctctgtc aatttcaatc ttatttaccc caagtggaag tacactgatt aagccctgct
    47221 cctgtgagtg atcaagtctt tttaacttgc aattatgctt attggcaatg gagctgattt
    47281 gagaaatggt attgtccagc ctttgaattg tccttgcaaa gttcataaag atgatggtta
    47341 cgacaaacat acgctcatct cttgtctgaa ggtcttttaa gaggcttttt acatcttccc
    47401 cataggtgat taaatcactt ggaagaatgt ccatatcata accgcttctt acagcctttt
    47461 tattctcctc aatcttcatc ttgtcaatat cggtattttt tctttttacc atcttgatgg
    47521 cttccgactg ttcgattgcc ttgatatgaa aagagatatt gatgttatcg tctatatcca
    47581 aaaactctgc aagcatacgg tctgaaagct cacttgcaag gatttgaaaa tgacttgctg
    47641 ctccgataaa tttcccaaac ttaaaatacc ttgacggtgt aaagttaaat tcatcaggag
    47701 caatatatgt ctttgtgctt tctttcttct ttaagtcctt atatgaaaat tcaaaggtct
    47761 tattgggatt taaaacatca tgaagtatct tcagcctttc ttctccgttt agactttctg
    47821 ctcttactcc catactttta agacttgata atatatctat ctccagtctt tcaagttttg
    47881 atgttgcctg ctctaaatta tccgcttcca ctgtaaaggt tacatacttt gattttttca
    47941 gtccgttatt tccctttaca atctggcttt tcagcatttc tctaaactca aggcgaatat
    48001 cgtcaaaacc gtccttttta tccggtattt gaatggctga tttcatttct tcatttctgc
    48061 caagctgatt aatatatgaa aactctatgc tgacacttgg atcaaaggaa ttaagaaaat
    48121 ttgcaaactg attaaaaatc aaatctctat cttcttctaa ggcaagctga tagtttatat
    48181 cctcaaaggc aatactctta ttaaaatgct tttcatcaat ctgacatatc ccgcttttta
    48241 agagtctaag atagggaatg gtatcttcaa cagtgtatct tttcggttct ttcctaaaga
    48301 taaggtcaag taatccgccc ctatcttttt tagactttcc cttattttgc tttaagtcct
    48361 gtttttgact tcttaacttc ttttggtttt gttctaactt tagctgctga atttttcttt
    48421 tgtctttcaa gataaacctc ctttctcact cttttttgtg gctgataaaa tttgtgaagg
    48481 taaatatact taaaatattt ctcaaagcta agtccgtcct tttcaaaaag agttatgaaa
    48541 aatataggga gagtggacac aatgagaaag atgactgcta tatcatttgg aacgaccttt
    48601 cgcataaata aatagattgg tattccaata agtcctgcaa tcgtaaaacc tataagctgt
    48661 cttttcgtca aattgaatgc aacctttgtt tttaccttct ttaagtcttt tgggataggt
    48721 acatacgcca taacttacct cccatcttct tttccctttg aaagctcctc tatatgctca
    48781 tatacggagc cgatttcttc ctgaatactt gcaatctgtt catctgtact tctgttatat
    48841 ctttcctgca ttagacaaaa atcattgtgg cagcgaccga tgtcttttgt tctttcttcc
    48901 aaatcattct ctttgatgtg aagcctgatt ctatccatca ctgccaaaat acctgttcca
    48961 actgctaccg ctatcaatac tgtttttctt ttgttcatca tatctatcct ttcttttagt
    49021 gtgcatttaa tacgcttttg gccagtgttc cgctctttag catcattaac cccagcaaaa
    49081 ccgcatatcc aagtatcgta aaggtacttg tgtgtatatc tgttatttgt attgtcttaa
    49141 ctaatactgc gtatattcca agacaaacca ttaaaaagag tccttgtaat cctatggcaa
    49201 ataagccttt gatatagttt gttccgattt gtccccactc tttgtttccc attgtggcaa
    49261 aaggaatggc tgaaacggat gagtaaacat aaatctcaaa cattctgccg tataccacaa
    49321 gcataatcac aatggaaatg acctgtattg ccacctttat gagcgaggtt tcaaagagta
    49381 tcatgacaag ctctccaaga cctttatctt ttaagccttc taccatcgtt acaatctgat
    49441 ctccagagat aacggcagag gtgttaatta cccctgccgc tttatttacc atgtgctgtg
    49501 ccacatcaaa gactgccata gaaaactgaa aagcatggga cactaaccat acggcaatcc
    49561 acatctttat gatgtatttg aaaaattcaa aggtatccgt atcgtgcata ttgttctttt
    49621 gcataaccat attgataagc tcgatacaaa ggactgccgt tatgattagc cctgcaatgg
    49681 ggataatgac agagtcgtta atgcttttga taaaactaaa aacctgtcca ttccacccca
    49741 tcggtgtctt tcccacatcc gttgcaatcg caccaacttt atcgttgatg tcaagaaaca
    49801 tggactctaa gtttgcttgg ataccgccca gtagaagatc tttgaaaaac tcctctatct
    49861 tgtcgaatat cccaaacatt taatttctcc ttttcttctt acttgagtac atttgcaaga
    49921 agcggaatca gctttaatcc gataaggaca ataccgcctc ctgccataag ctgcttaatg
    49981 ccctgagatt ttgcacccgg attgtcatta ccataacctt ccatcaggtt aataacgccc
    50041 catgctccaa gtcctgcacc tactgccata actaaaatct ttaatacatt tactgcctgt
    50101 gtaaaaaatt ccataattta ttcctcctcg ttttcttctt tcttttcaat tttgttgtat
    50161 gacttcacaa caaagttttt gtaagtcttt ccatcttttt cacgcttctt aaagtatcca
    50221 aagatatgga tcaaatcacc tttttcaaag gcttttgctg tttctgactt ttcaccatag
    50281 gctgcacaat tgatatattc cttgcctttc ccatactttt ttacaagcgt aaagtttaca
    50341 acttcaaccg tttctccctc tttgtcaaaa cttgaaaaag ttggttctgc caataagttg
    50401 gcattgatgt taatcatttc ttgcttcatt aaaaatttct ccttttcttt tcaataaaaa
    50461 aagcgatcgg agtttttctt ttccaatcgc tgatactctt gctatttagt tttccttagt
    50521 gggacttctt atccttacca tctttcctcc tgattttgag taataaaaaa gcagcaaatc
    50581 tatgttcttt agacttactg cactcttgta ataaccgttt ctctatttaa ttttgctttc
    50641 ccttttctct tgatatattc ctcaatatca aaggcatttt tcttattaaa atcttcaagt
    50701 aacttgtaat tcttatgctt tgtaatatca aatttatctg ataaaaacgg tcttacacct
    50761 ctaagctgaa agatacattt actgccatcc ataaccgtta tctcatcttg actcatcagc
    50821 tcttttcctg tcttttggta attgagtcca taactattag cattggagcg tgtttcagaa
    50881 gtgttatata gatctatcgt ttcctttcca agcgtttctg atagctcttt taatgtggtc
    50941 ttttcctttc cacctaaaaa caatgtacta tcacagttgc ccacgattgt gtcagcatta
    51001 tccttatata tcgcctttaa ctgagattgt gcttgcaaaa taatgcttgc agatatttct
    51061 cttgaacgga ttgtcgctat taacttctca aactttggaa ttaagccgat atttgcaaac
    51121 tcatcaagaa ggcatcttac atgaacaggt aatcttcctc catactcatc atctgcctta
    51181 tcacaaagta gattaaataa ctgtgagtac atgatagata ccacaaagtt aaaagtatca
    51241 tctgtatcag atataatgac aaaaagtgct gtctttctat ctccaagagt atcaagctca
    51301 agttcatctt ctttcatcaa gtccctaagt tcctgaatat caaaaggagc aagtcttgca
    51361 ccacatgaaa taagaataga cttcgccgtt tttccagcag caagtttgta tttcttatat
    51421 tgctttaccg caaagtgcgt aggctctttc ttttccaatg cttcaaatag tctatcaatg
    51481 ggattcatat atgtttcatc atcttccctg acttctgaag catctatcat atccagtagt
    51541 gtcgcaaagt tcttttcttc tcttggagct tcataaaaaa tataacctat caaagccgta
    51601 tagtagagtt tctcggcttt cacccaaaaa tcctcacctg ccttttcccc ttcaccctta
    51661 gtgtttgcaa tgattgtctg cactaatttg aggatgtctt tttcacttct gagataggca
    51721 aagggattgt acttcatact ctttttgaag ttgatggtat ttaagatttt tatctcatag
    51781 ccattatctt caagcatctt gccacactca atgactatcg ttcctttagg atctgtaaca
    51841 caatatgacg agtgcatttg cattaggttt ggctttacat aaaatctcgt ctttccggag
    51901 ccagaaccac caataacaag tacattctta tttcttgcat actttggatt tgccggtctg
    51961 ccattcatgg ttaatcgctc tgtttgagta agcaagatat tgttttggaa cttttcatcc
    52021 acatacggct ctatatcttt tctcgttccc catcgggctg aaccatactc tttcccctgt
    52081 ctgaactttt ttgcattttt acctttggta tagacaataa atttaattaa aactgccact
    52141 tccacgccca ttaaaatatc tattggatga atgctcggaa taaagctcat ggtattaagc
    52201 tctaatattc cttgaaatat tttatctatt acatcgccac ctgtataggc tcttacatgg
    52261 tgagagaaga tgtttccaac atagaaaaat gcaagatagg gaatattctg cttgaaaaac
    52321 tttgacttat cttgcacctt aaataagcct ttgatgtctt ttagtatctt atctatcata
    52381 ggctctgctc cttttgttta ttcttgactt tatctttaga aagagcgttc tttgccattt
    52441 ccttgaactt ctcaatattc ttgtggatag attcttttct ttccgttttc ttttctgatt
    52501 ccgaaagagc gtgtttaaag gctttatcca tgactttcat gtcttttgcc tgaaagaata
    52561 cggagtattt accgctttct ttatctttca tcaccgaaaa ctttacccca taccgattaa
    52621 gttccttttt cagttccttc agctctgctt cttctaccgg aatttcttca agctgtccct
    52681 ttttaaccat atcttttagc tttacttcat ttccgttagc attaaccagc ttttccagtc
    52741 ctccaagttt ttcagcctct ttcatcagtt tctttaataa gttcagaatt agctttcctg
    52801 ttactttagc agctttcact tccatgttaa gcgtttttct tgcgatttct tcattgatca
    52861 agttctctca cctccagtca gtaatctttc tttattcctc tttaattttt cttcctgaat
    52921 aactttcctg taattttctc cgagtaccat cacaggaata cacatctcga taattcttga
    52981 gtaaattctt tggtattcca cactctccgt acagttttca atttggctgt atgaaagatt
    53041 tgtggtaaag attgttggct tatgctttaa gtacctgtta ttgacaatgt tatatacctg
    53101 ctctttggca tagcttgtat ctctttcaat tcctaaatca tctaagatga gaacggaagt
    53161 gtttacaagg gattcgatat atgcgttttt atcaatgtca aatcctcctt tttgcagttc
    53221 gttgattatc tgtgaaaagt ttctaatctt aacgcttatc tgatactgtt caatcagtgc
    53281 attggcaata gagcaggcaa gataggtctt tccgcttcca actgttccat agaacagaag
    53341 tccgatattt tcctttttca tcaattcata atcttttaca aaattctttg cgatgataag
    53401 actctgattt tcttttccct gatagttttc aaaggtatat gaccactgaa taatagatgt
    53461 gaagcagata ctttttaatc tctcgatttc aagctgcttt tgtctttctt tttcttttgc
    53521 ttctctatct ctatcgcatt tacaagctgt cttaaatatc atctgctttc cgaaaaattc
    53581 taatgctttt ccatcttttc tttcatggca cactttacag taggcgtgtc cgtctttgat
    53641 gtattctttt tcaggattga agctgtattc cacatcttct atcatcactt tttctaattc
    53701 tttaatcata aatgtactcc cttgttatat tcctcccatg tagggatatt ggtttttttc
    53761 ttacttccct gatctttata aaaccaagaa aggattgttg ctttatggtc tttatatgtc
    53821 tttccggtac tttgaagata ggttgatagt ctttcaatgt agttatcaag ctctcctgcc
    53881 attattattt gtaattctcc tatgtcttcg tcctttaaaa agacattttg aaatgttcca
    53941 agtccgcttt tcccaaaact atattctctc ttactatact tactcttatt attctctata
    54001 tagttagagt caacattttg aacttcctga agttcatttt ctttacttct gaggttaaaa
    54061 tctcttactt ctgaagttaa gttttttgac ttctgaaagt cattttcttt taccgctatt
    54121 atgctcataa aatctttaac ataaatgaca ttcggcttac caagtccaag ccttactctt
    54181 tcaatcagtc ctattccttt tttgctgtct aactcgtcca atgtttttat ggcagtaggc
    54241 tttgagatat ttcttcttct cataatttct tcaacagtaa aatagataaa tactctgcct
    54301 tccttgtcca cccagttatt cttaaaggac attcctgtgc gtttcaaaag catggagtat
    54361 agaataatgg cttcagcaga cagtccctta aattcttctc cgtctactaa tatttcaggc
    54421 actttcagaa agttaaatcg ctctgcttct ctgttataga aatagtcaaa gtccatgcaa
    54481 gatcacctcc ctccttaaaa atttgcaaag aaaaagacga tagttttttc atctatcgcc
    54541 tttggtaacc atttttatga aattttttag attgatttta ttgcctcatt gataccttgt
    54601 aaaaaagcta taacagttgc cccaaccatc ggtattccgt atggactaac taagaatcca
    54661 ataatcaatg cttctattcc gatggtaact tctttttgca gaaaagatgc aattgctcca
    54721 aatatacaaa acatcatcag caaatatagt agggctgttc cgataccaag tagaaatgtc
    54781 agaaatgctg tgaggatact taacaccaag ctaattggga ataagattat ttttattatc
    54841 catctcataa tttcttattc ctcactttca aaaacattct ttgtatctcc acacaccata
    54901 tcaatgcaaa cattcacatc catataattt tttaagactt tttttcgtcc tccctctccg
    54961 tcttctacaa atacataatg cttgtaaaac tgcttaaaat gcagtatttt cactatttca
    55021 ctctttgtat caacgctatg cactccacat gatgcgtttg aggaaataga tccaccggct
    55081 ggactttctt caattcatat cccaattctt ggtagagttt gatatcacgc gccatggttg
    55141 ctacattgca ggagatatag gcgatgcgat cggctcctgt ttgggcgctt gctttgataa
    55201 agctttctgt caagcccttg cgtggaggat caaccaagat aacggttggt tgaatcccat
    55261 ctttaagcca attcttcata gcattttcag ctgtgtcaca gacataatgg gcgtttgaaa
    55321 tattgttcag ctgagcattt tttttactat tctcaaccgc ttctggaatc agttcaacac
    55381 cgtagacttc tttgacatgc ttggcgactg ataaaccaat ggttccaata ccagaataag
    55441 catcaataac cacgtcatct ttttttaact ctgcaaagtc aatggctgtt tgatagagtt
    55501 tctccgccat ttcagtattg acttggtaaa aggctgggcc agcgatttgg aagtcatttc
    55561 ccaacatctg gtccgtaata tagtcttgac cataaagagt gcgccactcc ttaccaaaaa
    55621 tcgcattggt attctggtcg ttgatatttt gcatgacaga cacaatctct gggaactgct
    55681 tgataacttg ttcaatcaat tggtcaacac gaaaaacttt tggacgagtt gtcaccaaaa
    55741 cgaccatgat ttgtcctgaa tagtgaccac gacgcaccac aagattccga atcaatccag
    55801 actgttcctt ttcgtcataa ggttttaaat caaaacgacg gagcaggtct cgaagagcta
    55861 ctacgacttg gtcaatgaca ggatcctgga taaagaaatc ttcaaggggc atgaggttgt
    55921 gcgaattctt acggaaaaat cctgtttcca agacaccatt cactcgacga acgggcacct
    55981 gcgccttatt gcgatacttg actggatgtt ccataccaag cgtttcagca acttctacat
    56041 ctgcaattcc agcaatcttg tagagactgt ccttgacttg cttggtttta aacttgagct
    56101 gttctggata agaaaggtgt cctaaatccg cgattcctga acgcaggtaa gccaaatcta
    56161 gatcttgatt acggtgtggt gactggacaa ggtatttttc aacttttcca aagccaatct
    56221 ttttattgac cttgaggaca cgcatgagaa ttttttcact cggtaaagca ttctctacaa
    56281 aaaagaccaa accatctacc ttggcaactc ctgccccttc atgggtcaaa tcaacaattt
    56341 caacttctac aatatcattt ttctttaaca ttcttttctc tttctattgg ccgacaaaaa
    56401 agacggcaac gttacggtta ccatccatta taccatgaaa tttcttaaga accaaaactc
    56461 ttgaagaagt tgacaagggc ttgccagagg gagcttaaga agttaccacc gtcctctagc
    56521 gccttatccg catcaaagtt aaggttgata tttttaaaac tgtcgccagc ttgtgatacg
    56581 atgctttgtt taaggtcatt tagggtttta gtgaaatctg cattgctgag gatatcactc
    56641 tttgagagat tcaaggcaaa attgatgatg atattgatct ggtttcctgt tatgacctga
    56701 tcaagtttgt aattttttaa ggtatcttca acaatcttgc ggatatcttc ttctgtcaga
    56761 tttcccttgc tttctttagc tttggcgagt cctgacttga tatcagctag ggcaacgttt
    56821 aatttattag catcatagcc tgatttgtcc ttgttttcag cattgatatc tgacaaagtc
    56881 tttagctctt cttgagccaa atctttattg gcttgcggca ccttggctcc attagcttct
    56941 agcgaatagt agatcccagc caaagcactc tcacctgtaa ctggaatggg tgctgctaca
    57001 gtgattttgg cgtgttccac acccaaagtt acggctgcat ttcggtacat atcctgagtt
    57061 accttagtga tgttttcagg tgtttcaatc ttgacctcaa gtggcgattt gtcacctagc
    57121 ttttgaatct tggctgatga atacaactgt aagctagagt cattggccac attcatgatt
    57181 ttagaataaa catcaggtgt catggtcttg agttctttgg tatctgttga ggcattgtag
    57241 cccagttttt taagagtttg atttttttgg tcttcagata gggaagaacc taggacatat
    57301 tcaggttgga cataggtttc atcgataact ttttgaacat ctgttgctgc atagacgcta
    57361 ttcatagctg ttactgccca caagatcgca gcgctagtca gaaagagttt ctttctcata
    57421 gggaatttcc tcctttactt ctttagagta atatatctat cttaaagaaa acttataaca
    57481 aaaacacctg gtctagccag atgttgaaaa gagagtgaaa catttgatga tgtaaaggtt
    57541 aagtcgtacc tgtctagaat aataatagtt tcctccattt acatagagtt cagcaccgtg
    57601 aaaaatggaa atgggatgaa tataactata agtctttcca gtcgtattac caagcaaggg
    57661 ggcaacagtc tcacgagagt actgtttggc tagagccaag gtattttcct tgccattttg
    57721 ggcgataaaa tcgatatagg caggtccaaa attataggct tgaacagctg tccagatatc
    57781 tacacccttc ttctgcgcca gatagagatt gcctgtcaga gtttgaatgc cttgccgaat
    57841 gctagaggca ttatcattga tggtgttggt ggaaccactt gcagactcac tagactgcat
    57901 aacatcgcct tcttttcctt ttgtttcagt ataaatcata gcaagcacaa gctcttcgtt
    57961 tgctggggtg tctttttcac tcaatatttc tcgcaccatg ggttgatagg tcatgacttg
    58021 tttgacatct tgatgaacgc ggtaagcttt atagccagca aaaaggaaga ctgctagtac
    58081 aagcactctt cgaattcgtt taaacattat ttactttgga tatcctcgat atttttgatt
    58141 aagatagagt aggttccatt ttcgttttgg ataaactcaa cagactcggc gtcttgatag
    58201 acgttattgg gaacgatgag ctcaattcca tttgataagg agagtttttg gttttcaaat
    58261 ttctttaatt ggcgactggc atcaatttca tcaaattgaa caggttctgg tacggcttct
    58321 ttgacttggt caataaagct caaacgagcc gtcagattgt tgtcaaaaag gtcattagcc
    58381 aatttctcag gtgacaattc attgctttct tctaggttgt tgaaaatcgc tgatttgacc
    58441 ttggattgaa attgaaaatc atctgtgtta aaagattcag caattctctg ggctgttttt
    58501 tccagttcct tgatagattt tttaggagaa atcttaggag cgacagcaag aagattatct
    58561 gaaaaatagt tcaaaaaagt cccgttgtac ttgattcgtt tttcaatcag gtgatacttg
    58621 cgactctgaa gattgaccac caaggcctcg tcagcacccg ttccaaatcc aggcaggtta
    58681 ttctgagtca gcttgattgg attatcaact tctcctccga ggtgggtcaa ggtctcccgc
    58741 agggcaattc gcaagaaagc gaaatgttct acaccttctt tagaaaattg aacaaaaatc
    58801 aagtcattgg tcttgagatt ttcagaaatg ctaaactcct ctttccagag attagccagc
    58861 gttactgatg tctccaacaa atcgtctgta atatgattga agaagggatt ttcttcttcg
    58921 aaaatcccag tcttggcttc atctgaatac acatgttcaa tttttttacg taggtattct
    58981 tcgatttttg gagtaatatt gagaaactta tctgctaaga acagctcggt atcatccgga
    59041 ctgaactggt gaataatggc tttcttaata taaatgtcca taaaagtttt attcctcgta
    59101 taatgggaag gcatctgtca attctttgac tgcacttctc acttcttcta atacagcctc
    59161 attttctgaa ttcttaaggg ttttaatgat gagttcagcc actttgcgac tttcttcttc
    59221 accaaattca cgtgcagtaa tagctgctgc tccgatacga atcccacttg tcttgaatgg
    59281 tgacaaggtt tcgtaaggga ttgaattttt atttagggta atattgactt catccagcaa
    59341 gttttgagca acttttccgt tttctacaac cttagtcaca tcaacaagga agagatggtt
    59401 ttcagttcca cctgaaataa tacggaaatc agggtcttgc aagaagacat ctgccatagc
    59461 cttgctgttc ttaattacat tggcagcata ttccttgaag gctggatcca aaacttcttt
    59521 gaaggaaact gccttagccg ccacaacatg ctctaaagga ccgccctgaa tacctgggaa
    59581 aatagctgaa ttgatttttt tagcaagttc ttcgtcattg gtcaaaatca aaccaccacg
    59641 aggtccacga agggttttgt gggtcgttgt tgttgtgata tgagcgtatg gaactgggct
    59701 tggatgaagg ccagccgcaa ccaagccagc gatatgggcc atgtccacca tgagcttcgc
    59761 accgacagca tctgcgattt cacggaattt tgaaaaatcg ataatttgag aataggctga
    59821 agcaccagct acaatcagtt ttggttttac ttcttgggct tgtttcaaga tagcatcaaa
    59881 gtctaagagt tccgttttag gatcaacact ataagaaaca aagttgtagg tttgaccaga
    59941 gaagctaaca ggagccccat gagtcaaatg accacctgat gccaaatcca ttcccataac
    60001 cgtatcacct ggctcaatca aggacatgta agccgcacag ttagcttggc ttcctgaatg
    60061 tggttgaaca ttggcaaatt tagcaccgaa aatttctttt gcgcgttcaa tagcaagagt
    60121 ctctacaacg tctactacat cagttccacc ataataacgg cgtcctgggt aaccctcggc
    60181 atatttattt gtcaagatag acccttgagc tgccataaca gccttggaaa ctacgttttc
    60241 cgaagcaatt aactcgatat tattttgttg gcgttcttct tctttggcaa tagcattcca
    60301 gagatcagca tcatatgctt taaaatcatc tttgtcaaaa atcataggtc ttctccttta
    60361 ttgtgtgact agtccattag tttgatttta caataagaaa atcaaactaa cagatgcgaa
    60421 taaaccgttt ctgcatttta tcacaagtat agccaacttt ttcataaaat gcatgagcac
    60481 ccagacgatg attggcagaa tttaagcgga taaacccata accacatctt tttgcttctt
    60541 cttccaaccc ttgtagtaaa cttttaccaa taccttgacc ttgcgcttga ggtgaaactg
    60601 ctaaagctaa gatattaaat cctgctttgg aatagagtga ttcgtaaact tcagcgtgga
    60661 catatccaag taagacatga ttagctgcat cctcatagcc aagtaggaaa tgatgggaat
    60721 cctgagacag tctagctagt tggctagccg tttcctctgg actaaaagta taacccaaag
    60781 cctcttggtt gatgtcacat atcgctttca catctgtttc ttgcaaatct cttagcattt
    60841 caagcctcct caaaagaaat ctctggcaac cgagcaagaa tatcttctcg tttaattgcg
    60901 ccttggcgta agattttcac cttgtctcca gacaaatcca caatagttga atcctgtcca
    60961 gttagaaaag catcgtcttc cagacccaga acctcttggt caaaatcctt cagaatttgt
    61021 tcaaaggtta caccacttgc ctgacctgag atattggcag acggcccaat caagggacct
    61081 gtctctcgaa ttaaatccag tgtgataggg tgactgggca tccgaaatcc aatagttgca
    61141 aggtcagaat ttacccaata gggaactcgg tcattggctt cgagaataat ggtcaaggga
    61201 cctggcaaaa aggtctctac aagtttttgt agataagctg gctgattctt tgaaaagtgc
    61261 aagatgtcct cgaaagaggc gatattgaga ttgagtgcct tatctctagg acgacgtttg
    61321 agttggtaaa catggtcaac tgctttttca tctaaggcct tggaaaaaag accataaaca
    61381 gtctctgtag gtagaacgac agctccaccc ttttccaact cttgtctaat cctgtccatc
    61441 atcaaccaca accatcctat tttgaccaaa ttggtctttg agtgttcgaa ctcttttttc
    61501 aggaagatgt tttctaaaaa gttcgggaac acattgacct tgcttgtatc caatttcaag
    61561 gtaaatctta ccactatctt tgagatagtc tgttgcatct tccgcaattc tacggtaaat
    61621 agctaggcca tcctcgtctg caaagagagc tagatgaggc tccgaataca agacattcaa
    61681 gcctacctct gactcatctt cacgagagat atagggtgga ttggaaacaa ttatatccta
    61741 tttttcagaa atttctgtaa aacagtcaga tttttttaaa aatatttgaa gattttgatt
    61801 tttagcattt tctctagcta aatctaaggc ctcttgagaa atatctgctg ctgtcactga
    61861 ccaatctggt ctattttttg ctagagcgag agcaatagct ccactacctg ttccaatatc
    61921 cagaactgag agattcgtct caagattttc agttagaata agctccacta actcctctgt
    61981 ttctggacga ggaatcaaaa cccgttcatc cacctttaaa tgcattccat aaaaatctgc
    62041 ctgtccaatg atgtactgag ctggcttgtg agctgctagt tgctggtaaa tatcttctac
    62101 aaattgtttt tcttcctctg ttgtcacctc ctgctggagg gcaaaaataa agtctgtaaa
    62161 agatagattt ttcagactac gatagacaaa agagaggctt tccgcttcct ctccttgtct
    62221 tatcaactct tcttcaaaat ttgaaaataa ttgagctaat ttcattattt gtttaattct
    62281 tctagttttt gtgtttggtc ataaagcacc aaggcatcca caacttcgtc caatttacca
    62341 gacaaaatcg tatctagttt ttggagggtc aagccgatac ggtggtctgt gacacggttt
    62401 tgtgggaagt tataagttcg gatccgttct gaacggtcac cagtaccgat tgtcgactta
    62461 cgctcagcgt cttgttcatc ctgagcaatc tgagcaaagt ggtcagcgac gcgtgcacgg
    62521 ataatcttca tagccttctc gcggttcttc tgctgggtac gttcttcctg catctcaacc
    62581 ttgatattgg ttggcaagtg aacgatacga acggcagtcg caaccttatt gacgttctgt
    62641 ccaccagcac cagaggcgtg atagatgtcg acacgaaggt cttttggatc aatgtcgtat
    62701 tcaacctctt caacttctgg cataacaaga actgtcgctg tcgaagtatg aacacggcct
    62761 tggctttctg tcacaggaac acgttgcaca cggtgggcac ctgattcata cttaagctta
    62821 gagtatacag actgacctga aaccatagca accacttctt taaaaccacc gacaccattc
    62881 atagaggctt ccatgacttc aaagcgccaa ccttgggctt ccgcatactt ttggtacata
    62941 gttagcaaat ctccagcgaa aagtgccgct tcgtctccac cagctgctcc acggatttca
    63001 aggatgatat tcttgtcatc gtttggatcc tttggaagga gcaaaatttt cagtttttct
    63061 tcatattctt ctttttcagc cttggcatct ttgagttctt gcttggccat ttcttccaag
    63121 tccgcatctc cgcctgattc cttaatcatc tcttcggcat cgacgatatt ttgaaggact
    63181 tgtttatact cacggtaggc tattacggtg tcacgattgg aagcttcttc ttttgaaagc
    63241 tccataaaac gcttggtgtc tgaaacgaca tcagggtcac tcagcaattc tcctagttct
    63301 tcataacggt cttctacagc ttgtagttga tcatagatgt tcattttttc tccttatttc
    63361 tcaattgtta aatcatagat tgctactact tcattctcgg atatttcccc agtttcttta
    63421 aatccataac tgaggtaaca aaatcttgcc tgttcatttt ctggttcata agacaaccaa
    63481 agtttattgc ttaaacctgc tggcgctgtt cgaacatagt ctagtacttt atccataatt
    63541 ggtttaaaat atccttgatt ttgaaaattc ttatcaatca taaaacgaaa tagtaaataa
    63601 tttccactac taattccgat ctttttatca taagctatca tcacaaaacc tataattgca
    63661 tcattatcat aaactgccaa tgtagctaca aaatctccat ttttagtgta gacgtatgct
    63721 tcagctaaac taattgcgtt ggttgcaatg aattgttttt gatattcctt gacatccaaa
    63781 tttaaaacat caaaataatt ttccattgta acatctctta gttcaattgt catagttttg
    63841 ctccttgtta gaggttatca ttggcgtaaa ataatgttta cggcaaactg agatataggt
    63901 ttcgttacca ccaatctgga tctgttctcc atcgtaaacg ggcagtccat cctgtgttcg
    63961 caacaccatg gtcgcctttt tcttgcaata ctgacagatg gtcttgattt cgtcaatctt
    64021 gtctgctaaa agcaagagat atttggaacc ttcgaacaat tcattgcgaa agtcattttt
    64081 caagccaaaa gccatgacgg gtatgtctaa ctcgtccaca acacgagcta ggtcgtaaac
    64141 atggtggcgt ttaagaaact gggcttcatc gaccaaaaca cagtaaggtt tttctggtag
    64201 gtctcggata tagccaaaga tatccgttgt ttcctcaatc gcaagggcag ggcgtttcat
    64261 gccaattcga ctcgacacat agccaacacc gtcacgcgta tccagagccg aggtcataat
    64321 gacaacacct tttccttgct cctcgtagtt ataggccact ttgagaatct caatcgtttt
    64381 accagagttc atggtcccat aacgatagta caactgtgcc atgtttcttg cttcacgtcc
    64441 atttctaaat ttttgctaca ttctagtata tcataatttt cttaagcttt aaacggcaaa
    64501 atgtggtaaa atggaagaaa tcaaaactag tggaggaagc tattatgcca tttgtacgca
    64561 tcgatttatt tgaaggacgc acgctcgagc aaaagaaagc tcttgctaag gaagtaacgg
    64621 aagcagttgt ccgcaacact ggagcccctc aatctgctgt ccatgtcatc atcaacgaca
    64681 tgccagaagg aacttacttc ccacaagggg aaatgcgtac taaataagct agcttaagca
    64741 gaattgctta ggctttttca atctccaagt agcattcatt gaagaaatat cctaaatttg
    64801 ttacaatttg aaaagaaact tggagaattt ccaagaaaag agctattaat taaaggaaac
    64861 attatgatta cacgtgaatt tgataccatc gctgctatct ctactccact aggtgaaggg
    64921 gctattggta ttgtccgcct gagcggaaca gacagttttg ctattgcgca aaagattttt
    64981 aaaggaaaag acttgaacaa ggttgccagc cacactctca actacggtca cattattgat
    65041 cctctgactg gtaaagtcat ggacgaggtt atggttgggg ctatgaagtc tccaaagacc
    65101 ttcactcgtg aggatattat cgagattaac acccacggtg ggattgcggt gaccaatgaa
    65161 attctccagc tagctattcg tgaaggggct cggttggcag aacctggtga atttaccaaa
    65221 cgtgcttttt taaacggtcg cgtagacttg acacaggcag aggctgtgat ggatatcatc
    65281 cgtgccaaga ctgacaaggc catgaacatt gcggtcaaac aattagacgg ctccctttct
    65341 gacctcatta acaatacccg tcaagaaatc ctcaatacac ttgcccaagt tgaggtcaat
    65401 atcgactatc ctgaatatga tgatgttgag gaagctacta ctgccgttgt tcgtgagaag
    65461 actatggagt ttgagcaatt gctaaccaat cttcttagaa cagcccgtcg cggcaaaatc
    65521 cttcgtgaag gaatttcaac agctatcatc ggacgtccca acgttgggaa atccagcctt
    65581 ctcaacaacc tcttgcgtga ggacaaggct atcgtaacag atatcgctgg gacaacacga
    65641 gatgtcatcg aagagtacgt caacatcaat ggtgtacctc tcaaattgat tgatacagcc
    65701 ggtattcgtg aaacagatga catagtggaa caaatcggtg ttgagcgttc gaaaaaagcc
    65761 ctcaaggaag ccgacttggt tctactagtg ctaaatgcca gtgaaccact gactgcgcaa
    65821 gacagacaac ttcttgaaat tagccaagat accaatcgca ttattctact taataaaacc
    65881 gacctgccag aaacgattga aacttcgaaa ctacctgaag acgttatccg tatttcagtc
    65941 cttaaaaacc aaaacatcga caagattgaa gagcgaatca acaacctctt ctttgaaaat
    66001 gctggcttgg tcgagcaaga tgctacctac ttgtcaaacg cccgtcacat ttccctgatt
    66061 gaaaaagcag ttgaaagcct acaagccgtt aatcaaggtc ttgagctggg gatgccagtt
    66121 gatttgcttc aagttgactt gactcgtact tgggaaatcc tcggagaaat cactggggat
    66181 gctgctccag atgaacttat tacccaactc tttagccaat tctgtttagg aaaataagaa
    66241 aaatccatga tccttcattc ggtcatggat tttattgtct ttattagtaa tctggtctta
    66301 agacccctgt tacagttgcc ttagttgctt cgtagtcgcc atctacgaca accttgataa
    66361 tgcgtttggc atcttcttct ggtgctggaa caagaggtag acgagtgggt ccagcttcaa
    66421 atcccatata gttaagaatt gccttaactg gagcaggact tggataagag aagagagcat
    66481 taaccttagg aatgaattta cgctgaattg ctgcggcttt cttcatatcg ctttctgcaa
    66541 tggcagtaaa catctcgtgc atttcatccc catttgtatg agaggcaaca gaaataaccc
    66601 catccgcccc aaggttcatg gcatggaaag catctccatc ctcacctgta taaatcaaga
    66661 actcttcagg cttgtgctca atcaagtaag ccatattagc caagctagta cattctttga
    66721 caccgataat atttggatgg tcagccaagc gaagcatggt ttctggagtc aattcgacaa
    66781 ctacacgccc tggaatgtta tagataataa ttggtaggtc agaagcatct gcaatagtct
    66841 taaagtgctg atacatccct tcttgagaag gtttgttgta gtaaggaaca atagcaagcc
    66901 cagctgcgaa accaccaaat tccgctactt ctttgacaaa ctcaatagaa tcacgcgtat
    66961 cattagtacc tacacccgca atcaaaggaa cgcgtccatt gacaaccttt tgtacagccg
    67021 caaacaactc caactcctca tcgtgggtca aagttggact ctcagcagtc gttcctgcga
    67081 gaagaattcc atccgtatga tgggccaata aatgctcaat caaggctgga atagcatcaa
    67141 agttaatgga accatcctca tggaaggggg taataaaggc tgtaatgatt ttacattctt
    67201 ttaaatcttg ataagacacg aaaacacctc tctatttcaa agaaggagtt catctgaact
    67261 cctaaacgat atgactattt taattcaaat ttcaattcgg ctgttggacg aaccaatcca
    67321 cgttcatgaa gagtttcagc aatctgaact gagttccaag cagcaccttt gagaaggtta
    67381 tctgaaacaa cccacatgtg aattcctttt tctgcatcca agtctttacg gatacgacca
    67441 acaaaggtat cacgcgaacc aactgcattg atagcttgag gatagatttg atgagctaca
    67501 tcatcttcaa gaacagcacc tgggaaggct gcgatagctg cttttacttc ttcgattgga
    67561 gccacttctt ttgtttcgat ataaacagac tcagagtgag ctgacaagac tggaatacgc
    67621 acacatgttg cagatactgc aatgctatca tcttccataa ttttcttagt ttccttggtc
    67681 atcttcatct cttcgtacgt gtaatcatta tcagtgaaaa catcaatttg tggaagagcg
    67741 ttaaaggcga taggataatg tttcttgtca ccacctgaag gcaaaatttc cgcatgcaaa
    67801 tcacatggtt tcacaccatc attcaagact tcacgaagtt cacgttgtgt ctcaagaatt
    67861 gctcccatac cagcacctga aacggcttga taagttgaaa caatgatacg gtccaagccc
    67921 catttttggc gaaccggctc aagagccacc atcatttgga ttgttgaaca attagggcag
    67981 gcaatgattc cgttgtgagc atcaagtgca tgagcattga cctctggaac aaccaaagga
    68041 acatctggat tttgacggaa ataagatgta ttatctacta ctaccacgcc agcttttact
    68101 gcgtatggtg catacttagc tgatgtagaa ctacctgctg aaaagagagc aatatcaact
    68161 ccttcaaaag ctgtttcagt cgtttcttca attgtaatat cttgatcttt aaatttcaat
    68221 gacttacctg ctgaacgtgc agaagcaagg taacggattt tatcgattgg aagtgttgat
    68281 tcttccaaca tttttatcat ctgagcaccg acagcacctg tcgcgccgac tacagcaact
    68341 gtatatccca taaataacct ctttcggaat tttctaaaaa tttctataat agaagtatta
    68401 tactactttt tccatgaatt gcaaagcttt ttcatcattt tttggaaaat aaaaatccca
    68461 gtcgctagac tagggactaa gaggcatctt catgtgatga gcaggttcac acaactcatc
    68521 aaggtccgct cctgcgttat gacctcctta tgctcaatag tagtccgaag actacctatc
    68581 gactcatcgc atattctata ttactagaga tacttgattt tgtcaataag aaattttttc
    68641 gatcgagtat aacaaaaaac tctcgtattc aagagtttcc ctatacatat catgctaatt
    68701 gccgggattg aaccggcgac ctcatcctta ccatggatgc gctctgccaa ctgagctaaa
    68761 tcagcttact taagaagtat actatattca gaaaaacttg tcaagtttcc ttagaaattt
    68821 tccataggaa aaagccaggt aagaactacc tagcttatct tcttctattt acttaaatca
    68881 attcgacgac caattttacc aataataatc gctccaataa tcaatgaagc aaattcaccg
    68941 attcctgttg taaaccaagt aaggaagaat ggtaattctg ctacaatatt taactctgca
    69001 gcgatagtaa acatggaaat tgaaaagagg attgaaaaga agaaatgatc ttttcgaatc
    69061 aatccattaa agaggtaatc cttgctatat tttgcaaaaa gccaaacacc taaactgagg
    69121 aatactaagg ttgaaccacc accaacaaag acatctagca gtccgaagct aaagaaatta
    69181 gcaatcatac aaccgatggt aactccgatg atgtacttag gattgtaaaa agccataaag
    69241 ttcatcattt ctgaaatacg aaactgataa gcaccatagc tgatggcatt taggggcggt
    69301 gtgacagtca aaacgacgta gatagcagcg acgattgcaa tatctgcaac atcacgaata
    69361 gttaattttt tcatcttttc tcctttggcg gttatccgcg tgtaatatgc ttggtgaaag
    69421 aagctaagca ccaagggttg attcattcaa ccttactagt atagcacaat agcctgcttt
    69481 atgctatact taaagcatga aaaaacctat tcaaaaattt tttaacaatg aaatcttagc
    69541 ctatctcttt tttggccttg cgacaactct agtttcgatt ctctcacgac tagtcattta
    69601 tcaactaagt catcaggaac tcctggctac tgccctagca aatattatcg gtatcctatt
    69661 tgcctttatc acaaatgata cgattgtatt taagcaaaaa aagaaaaata gacttatccg
    69721 tttagtgaaa ttttctcttg ctcgcctttc tacttttctg ttagacttgt ttttaacttt
    69781 tctctttgta acccaatttc ctcacattat agggcaattc gtaactgaaa acattgataa
    69841 gataaatgct attgaaacaa taattgcaca aatattcatt attatcatca attatatctt
    69901 gagcaaggcc tatattttta gaaaataatg ctccatttat gagcctttta attgccttct
    69961 ataatgattt aggatacaat gaaacacgaa acattgaaag gaaaacagta tgttaaaaaa
    70021 tctaaaatcg ttcttgcttc gaggaaatgt tattgacctt gctgtcggtg ttgtcattgc
    70081 ctctgctttt ggtgctatcg ttacttcact tgtaaacgac attatcactc ctcttatttt
    70141 aaatcccgct ttgaaagctg ctaaagttga acgtatcgct caactttctt ggcatggagt
    70201 cggctatggt aacttcttaa gtgctattat caattttatc tttgtgggta ccgccctctt
    70261 ctttattatc aagggcattg aaaaagcaca gaaactgact ggcataaaga aagaaaaaac
    70321 tgccgaaaaa aaaccaaccg aattggaagt ccttcaagaa ataaaagctc tccttgagaa
    70381 aaaataatcg attaaaagga tctagcgcaa agctaaatcc ttttttcttt actctttggg
    70441 taacttgcct gctttttcaa gcattttttt gataagataa ggcatcttaa cattctcccg
    70501 cccttttttc tcaatcagtt ttttcacaaa ttctggcatt tgtaaatctt cagattcagc
    70561 taaaatgttt ttcgtctcgt ctgaaggaac taactcatca aaggtctctt cttctgggag
    70621 aaattcctta aactcttgat tttcattgac tctaactgta ttgaccaaag catcaatcaa
    70681 acgagaatct gtatttggca ttggtggacg atggtagttt accccaaatt cctggcataa
    70741 gtcataacat tctacatcat tgtcaaacaa gacctcaata tgctcactga tgaaactaat
    70801 aggtacaaaa atataatggt ctggatgtgc tgtctgttct ctgagatact ccaaaacatc
    70861 tggtttaatc catggaatac caatatcact ctcactctgc caagtgttgg tatattgttc
    70921 tgaactcaag cccagttttt caacgactag cttgctattt tcgaaaattt ggtctatata
    70981 aggatcacca aagtccaagg caaaaatagg cacactatgg gctgaaaaga tgattttaaa
    71041 gctgtcttgc tttacttctt cttttaaaat cttagcaatt tcatctgccc aatagtttaa
    71101 gagcgcttct tcctgatacc agtccttaat gaccaaaaat tgaatttgtt tgctttctaa
    71161 aaatttttca tagcccatga cagagtagaa agaataatgg ggctccaaaa tcaagcaaat
    71221 acactgttca attccgtctg cttccatttg accgatcaca tctggaataa agggactgga
    71281 aaacttatta gcaaagtaga cactgtattc attccccagc ctagcttcta ccaaggcaac
    71341 ctcttgatgg gtaatttttt gcagaggcgt gcctccaatt cgtacataat tatcatagag
    71401 agtctgaatc tcgtggtctt ggggtctcac cccacgacga atatttgtga aaaaatcagc
    71461 tacaccttca aaggtagtct cttctggtga accgaaggtc atcattaaaa ttgctttttt
    71521 catgactgct tccttgtgat gtttttatca agtttatttt atcattaatt catcgataag
    71581 taaacgctaa catagggaca ttctcaatct tctgtctttt gtttttctct tctttctatg
    71641 atacaatgga aaaaataaat tcaaaaggag ttttttatga cttatccaaa tctcttggac
    71701 cgcttcttaa cctacgttaa ggtcaacacg cgctctgatg aacactctac tactactcca
    71761 agtacacaga gtcaggttga cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt
    71821 ggactgcaaa atgtttacta tctaccgaat ggttttgcta ttggaacctt gccagccaac
    71881 gatccgtctt taacacgtaa gattggtttt atatcgcaca tggatactgc tgattttaat
    71941 gctgaaggag tcaatccaca ggtaattgaa aactacgatg gtggtgtgat tgaactaggg
    72001 aattctggtt tcaaactcga tccagctgac ttcaagagtc ttgaaaaata tccaggacaa
    72061 acgctcatca caacagatgg aacaagcttg ctaggtgctg atgacaagtc aggaattgct
    72121 gaaattatga cagccattga atatctaact gctcatcctg aaattaagca ctgtgagatt
    72181 cgtgttggtt ttggtccaga tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa
    72241 gattttgatg tggattttgc ctacactgtt gatggtggtc cactaggtga acttcagtac
    72301 gagactttct cagccgctgg tgctgaattg catttccaag gtcgtaatgt ccaccctggt
    72361 actgccaaag ggcagatggt caatgccctt cagctagcaa ttgattttca taatcaactt
    72421 ccagaaaatg accgacctga gttaactgaa ggttaccaag gtttttacca tctaatggat
    72481 gtgacaggta gtgttgagga ggcgcgtgca agctacatca ttcgtgattt tgaaaaagat
    72541 gcctttgaag cgcgtaaagc atccatgcaa tctatcgctg ataagatgaa tgaagaactt
    72601 gggagcgacc gtgtcactct caacttgaca gaccagtact acaatatgaa agaagtcatt
    72661 gaaaaagata tgactccaat taccattgct aaagccgtta tggaagatct aggtatcacg
    72721 cctattatcg aaccaatccg gggtggaaca gacggctcta agatttcctt tatgggaatc
    72781 ccaactccga atatctttgc aggtggcgaa aatatgcacg gacgttttga atacgttagc
    72841 cttcagacta tggaacgtgc agttgatacc atcattggca tcgtagctta taaaggctaa
    72901 aaagacgagg tagctcagct acttcgcctt tctttttatt ctactggttt ttcttgattt
    72961 ccagtagttg tagaagattc tgttgtttca ttttctgaag ttgattcagc aggtttagaa
    73021 tctcttgtat tgcttggttt gttttcgtcg ctagcagttt caatgttaga ttctgcagtt
    73081 gcgtttggtt ggttctcagc actggtgtta tcaccatttg cttcagcatt tcttgctgga
    73141 cttgtttctt cacttgcgct agcttttgac tggatttgat gattcaaaac tagaatagct
    73201 tttgtcgatt caagtaaagc tgttttgtct ttactcttag cagaaagttg atctaataat
    73261 gcatccacct tatcaaagtc cgcatcagat ccattattac tttctaaata agagtgaagc
    73321 gacatgagaa tatcgtagag tttttgatag agtacaagtg tctgaggatc ttgctcagca
    73381 ttttcctttt cttgttgaag ggcgctagcg atacgagtca agacatcttt tacctgactg
    73441 tttacttcat ccaagtctgc atcagccttg tttgtggcag cttttagatt ttctacttct
    73501 tctgccaagg attgtctgat tccttcttca tggatttgtt ccaagagttg atttgccttg
    73561 ctcaaaagac tttctacttc ttccttgcta tctgtcgcag attattggtt gctatctacc
    73621 atgtactcct aaaacaggag agttataatc caagattaca aggccttaca gaaataagaa
    73681 atccagataa gacaatgttc gtccaagacg ctattcgctt cgcacagcag cacggattca
    73741 atatgcttta attttaaagt ttaggtgtca agacctcttt ttagtgtgcc caaaatttag
    73801 agaagtaatc aatcaactaa cttttatttt tttcaaactt tcagtaaact gacctaaagc
    73861 taactcaatc tgtctttgta gatgcttctg ctatcagcta gaagttgatc tacttttgcc
    73921 aagactgcct tctcatcaaa agttccaggt tgatagttgg attgcaggga tggaatcttg
    73981 tttttcaaag ccgcttcata tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca
    74041 tgaggaatca caaaaccttc tgaatcttca cttataattc gattggcatc aaaaccatga
    74101 ccatcttctt cctcatgatg gacatgtagt gacggattac ttaatacaga actagaagaa
    74161 cttcctacct cttccgtgtt agagtgtgat gggggattgt taagagatga cttaggaata
    74221 tagtgatagt gatccccatg tcttactata taagcatcac ctgtatctct gacaatatca
    74281 ttagggttaa agacatatgt ggctgctaat tcacctgccg acaagtcact ctcaggaatg
    74341 aaatgatagt gaccaccatg tggtactata gtagattgaa atagaatatg agcaaattga
    74401 taaggggatt ttaaagtaat ttctaacaat gatttagaaa ctatgatgtg ctattctaaa
    74461 ttcaactcac tatatataac catcatcggt agtataacgt ccctgtaatt ttgctacaga
    74521 tacttctgca ctagctcctt tatcgtcttt accatgttct tgtttttggc gattgatttc
    74581 atcttttgtt cgtacatttt ctgcatgagc ttgatcttta aggtaaacat aatactttcc
    74641 atctacctta ataatatatc ctcccttaac ctaactgacg atatcttgat ctttcggctg
    74701 atagttgggg gctttcatta atagctcttc actaaagagc gcatcaaaag gaactttacc
    74761 attatagtag tgataatgat cgccatgaga agttacataa ccttgatctg taatcttaat
    74821 aacaatttgt tttgcttgaa ttccttcttt ttgactaacc tagtctggag tcaaattttc
    74881 agtcttctta gtgtctttat tactgtttac atatgaaaca cgatttttat ctgtattggc
    74941 ctgttagcta tgttggttca gagcataaac acacagactt aaggaaagga taacaacaga
    75001 tccagctgct atatatt
//
LOCUS       DAVHSL010000003        74103 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000003 DAVHSL010000000
VERSION     DAVHSL010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.003"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..357
                     /locus_tag="VVR39_000145"
     CDS             <1..357
                     /locus_tag="VVR39_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029703.1"
                     /translation="LLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            556..2130
                     /locus_tag="VVR39_000146"
     CDS             556..2130
                     /locus_tag="VVR39_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6029704.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            2394..3182
                     /gene="codY"
                     /locus_tag="VVR39_000147"
     CDS             2394..3182
                     /gene="codY"
                     /locus_tag="VVR39_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU6029705.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            3182..3757
                     /locus_tag="VVR39_000148"
     CDS             3182..3757
                     /locus_tag="VVR39_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6029706.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            3839..3924
                     /locus_tag="VVR39_000149"
     tRNA            3839..3924
                     /locus_tag="VVR39_000149"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3873..3875,aa:Leu,seq:aag)
     gene            4207..5337
                     /gene="ugpC"
                     /locus_tag="VVR39_000150"
     CDS             4207..5337
                     /gene="ugpC"
                     /locus_tag="VVR39_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU6029707.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(5484..5630)
                     /locus_tag="VVR39_000151"
     CDS             complement(5484..5630)
                     /locus_tag="VVR39_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029708.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            5838..6596
                     /locus_tag="VVR39_000152"
     CDS             5838..6596
                     /locus_tag="VVR39_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6029709.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            6683..7195
                     /locus_tag="VVR39_000153"
     CDS             6683..7195
                     /locus_tag="VVR39_000153"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU6029710.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            7377..8321
                     /locus_tag="VVR39_000154"
     CDS             7377..8321
                     /locus_tag="VVR39_000154"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU6029711.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            8330..9007
                     /locus_tag="VVR39_000155"
     CDS             8330..9007
                     /locus_tag="VVR39_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU6029712.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRYEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            9105..9863
                     /locus_tag="VVR39_000156"
     CDS             9105..9863
                     /locus_tag="VVR39_000156"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU6029713.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            9901..11405
                     /gene="lytC"
                     /locus_tag="VVR39_000157"
                     /pseudo
     CDS             9901..11405
                     /gene="lytC"
                     /locus_tag="VVR39_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            11901..12419
                     /locus_tag="VVR39_000158"
     CDS             11901..12419
                     /locus_tag="VVR39_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU6029714.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            12549..13055
                     /locus_tag="VVR39_000159"
     CDS             12549..13055
                     /locus_tag="VVR39_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU6029715.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            13055..13225
                     /locus_tag="VVR39_000160"
     CDS             13055..13225
                     /locus_tag="VVR39_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029716.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            13257..14489
                     /gene="clpX"
                     /locus_tag="VVR39_000161"
     CDS             13257..14489
                     /gene="clpX"
                     /locus_tag="VVR39_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU6029717.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            14498..15085
                     /locus_tag="VVR39_000162"
     CDS             14498..15085
                     /locus_tag="VVR39_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU6029718.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            15096..15476
                     /locus_tag="VVR39_000163"
     CDS             15096..15476
                     /locus_tag="VVR39_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU6029719.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            15528..16418
                     /gene="rapZ"
                     /locus_tag="VVR39_000164"
     CDS             15528..16418
                     /gene="rapZ"
                     /locus_tag="VVR39_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU6029720.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            16415..17392
                     /locus_tag="VVR39_000165"
     CDS             16415..17392
                     /locus_tag="VVR39_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU6029721.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            17389..18300
                     /gene="whiA"
                     /locus_tag="VVR39_000166"
     CDS             17389..18300
                     /gene="whiA"
                     /locus_tag="VVR39_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU6029722.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFSLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(18334..19302)
                     /locus_tag="VVR39_000167"
     CDS             complement(18334..19302)
                     /locus_tag="VVR39_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6029723.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLAKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAIKYIDPEQKVQPKHSTSL"
     gene            19438..20295
                     /locus_tag="VVR39_000168"
     CDS             19438..20295
                     /locus_tag="VVR39_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU6029724.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            20282..21061
                     /locus_tag="VVR39_000169"
     CDS             20282..21061
                     /locus_tag="VVR39_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU6029725.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            21085..22437
                     /locus_tag="VVR39_000170"
     CDS             21085..22437
                     /locus_tag="VVR39_000170"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU6029726.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            22511..22885
                     /locus_tag="VVR39_000171"
     CDS             22511..22885
                     /locus_tag="VVR39_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU6029727.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            22887..23735
                     /locus_tag="VVR39_000172"
     CDS             22887..23735
                     /locus_tag="VVR39_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6029728.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGMIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGSGSIAL
                     GYIPVI"
     gene            24012..24779
                     /locus_tag="VVR39_000173"
     CDS             24012..24779
                     /locus_tag="VVR39_000173"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU6029729.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            24791..25975
                     /locus_tag="VVR39_000174"
     CDS             24791..25975
                     /locus_tag="VVR39_000174"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU6029730.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            25972..27843
                     /locus_tag="VVR39_000175"
     CDS             25972..27843
                     /locus_tag="VVR39_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6029731.1"
                     /translation="MSDFIVEKLTKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYECYEYLSEFDS"
     gene            complement(27986..29170)
                     /gene="mntE"
                     /locus_tag="VVR39_000176"
     CDS             complement(27986..29170)
                     /gene="mntE"
                     /locus_tag="VVR39_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU6029732.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            29474..32170
                     /locus_tag="VVR39_000177"
     CDS             29474..32170
                     /locus_tag="VVR39_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU6029733.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFTQRKLGFDKNAI"
     gene            32183..32974
                     /gene="yghU"
                     /locus_tag="VVR39_000178"
     CDS             32183..32974
                     /gene="yghU"
                     /locus_tag="VVR39_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU6029734.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQVGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            33090..33500
                     /locus_tag="VVR39_000179"
     CDS             33090..33500
                     /locus_tag="VVR39_000179"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6029735.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            33512..35107
                     /locus_tag="VVR39_000180"
     CDS             33512..35107
                     /locus_tag="VVR39_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029736.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLIKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            35274..35438
                     /locus_tag="VVR39_000181"
     CDS             35274..35438
                     /locus_tag="VVR39_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU6029737.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            35517..36245
                     /gene="yaaA"
                     /locus_tag="VVR39_000182"
     CDS             35517..36245
                     /gene="yaaA"
                     /locus_tag="VVR39_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU6029738.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(36296..37780)
                     /locus_tag="VVR39_000183"
     CDS             complement(36296..37780)
                     /locus_tag="VVR39_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6029739.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            37996..44487
                     /locus_tag="VVR39_000184"
     CDS             37996..44487
                     /locus_tag="VVR39_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6029740.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKNKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQITY
                     KVHRFGNETVLGLPISNRVTKEAKPRIMQIGVAKELIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQGAKGEKGARGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGDQGERGLTGAQGA
                     KGEKGAQGERGLTGAQGAKGEKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGN
                     VTSTVVRDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGA
                     KGEKGDKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVR
                     DGFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDK
                     GADGAKGEKGDQGERGLTGSKGEKGDQGERGLTGAQGAKGDKGEQGLQGRDGAQGPKG
                     ADGQRGPAGPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQP
                     LATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKT
                     PTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKN
                     GDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKG
                     ADGAVGRDGRDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGP
                     KGDKGADGAKGEKGDRGERGLTGAQGAKGADGAAGRDGRDGRDGKDVLNGKVNPEANQ
                     GKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHS
                     TDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDG
                     KYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKP
                     LAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAIGQ
                     DGQTPTITTQRGQDGQSTVVTITTPGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSR
                     IRRATDAAATPTRNGIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPTIT
                     TKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTK
                     ETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKAATATTTENPDGS
                     HTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVR
                     DGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGA
                     DGKETTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDGVSPTVT
                     VENNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVT
                     KTVIKDGKDGRDGRDGRDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQ
                     PTPNVPTPEVPVQPTPAVPTPEVPVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDK
                     LPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(44724..45272)
                     /locus_tag="VVR39_000185"
     CDS             complement(44724..45272)
                     /locus_tag="VVR39_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6029741.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            45593..46081
                     /locus_tag="VVR39_000186"
     CDS             45593..46081
                     /locus_tag="VVR39_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU6029742.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            46078..47265
                     /locus_tag="VVR39_000187"
     CDS             46078..47265
                     /locus_tag="VVR39_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6029743.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            47258..47623
                     /locus_tag="VVR39_000188"
     CDS             47258..47623
                     /locus_tag="VVR39_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6029744.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            47639..48985
                     /gene="asnS"
                     /locus_tag="VVR39_000189"
     CDS             47639..48985
                     /gene="asnS"
                     /locus_tag="VVR39_000189"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU6029745.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPVAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            49138..49428
                     /locus_tag="VVR39_000190"
     CDS             49138..49428
                     /locus_tag="VVR39_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU6029746.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            49440..49910
                     /gene="ssbA"
                     /locus_tag="VVR39_000191"
     CDS             49440..49910
                     /gene="ssbA"
                     /locus_tag="VVR39_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU6029747.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            49942..50181
                     /locus_tag="VVR39_000192"
     CDS             49942..50181
                     /locus_tag="VVR39_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU6029748.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            50476..51876
                     /locus_tag="VVR39_000193"
     CDS             50476..51876
                     /locus_tag="VVR39_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU6029749.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            51878..52237
                     /locus_tag="VVR39_000194"
     CDS             51878..52237
                     /locus_tag="VVR39_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU6029750.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            52291..53040
                     /locus_tag="VVR39_000195"
     CDS             52291..53040
                     /locus_tag="VVR39_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU6029751.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            53030..53329
                     /locus_tag="VVR39_000196"
     CDS             53030..53329
                     /locus_tag="VVR39_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU6029752.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            53400..54335
                     /locus_tag="VVR39_000197"
     CDS             53400..54335
                     /locus_tag="VVR39_000197"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU6029753.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            54422..54934
                     /locus_tag="VVR39_000198"
     CDS             54422..54934
                     /locus_tag="VVR39_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU6029754.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            54959..55567
                     /locus_tag="VVR39_000199"
     CDS             54959..55567
                     /locus_tag="VVR39_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU6029755.1"
                     /translation="MFGELNRYLDQYEDVILREIKAQFPDIAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYVLKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            55668..55865
                     /locus_tag="VVR39_000200"
     CDS             55668..55865
                     /locus_tag="VVR39_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6029756.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     ENAKGAVEGAVEGLKNVFTKE"
     gene            complement(55908..57353)
                     /locus_tag="VVR39_000201"
     CDS             complement(55908..57353)
                     /locus_tag="VVR39_000201"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU6029757.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKILAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISQDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQNHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            57459..59081
                     /locus_tag="VVR39_000202"
     CDS             57459..59081
                     /locus_tag="VVR39_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6029758.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVSKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMSLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            59284..61242
                     /locus_tag="VVR39_000203"
     CDS             59284..61242
                     /locus_tag="VVR39_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6029759.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            61414..61959
                     /locus_tag="VVR39_000204"
     CDS             61414..61959
                     /locus_tag="VVR39_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029760.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            61968..63089
                     /locus_tag="VVR39_000205"
     CDS             61968..63089
                     /locus_tag="VVR39_000205"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029761.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETSFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIY
                     SSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKIAFVGPSGSGKSTIVRLLERFYKPLSGYILMEQSSIYDFNLKEWRSKIAWVSQNNA
                     VLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGR
                     SQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVK
                     DVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            63247..64341
                     /locus_tag="VVR39_000206"
     CDS             63247..64341
                     /locus_tag="VVR39_000206"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6029762.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            64349..65515
                     /locus_tag="VVR39_000207"
     CDS             64349..65515
                     /locus_tag="VVR39_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6029763.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            65608..68706
                     /locus_tag="VVR39_000208"
     CDS             65608..68706
                     /locus_tag="VVR39_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6029764.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDILLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFESDFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            68754..69371
                     /locus_tag="VVR39_000209"
     CDS             68754..69371
                     /locus_tag="VVR39_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6029765.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            69382..70716
                     /locus_tag="VVR39_000210"
     CDS             69382..70716
                     /locus_tag="VVR39_000210"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU6029766.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAIYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            70726..71190
                     /locus_tag="VVR39_000211"
     CDS             70726..71190
                     /locus_tag="VVR39_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029767.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            71187..71681
                     /locus_tag="VVR39_000212"
     CDS             71187..71681
                     /locus_tag="VVR39_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029768.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            71762..73417
                     /gene="mltG"
                     /locus_tag="VVR39_000213"
     CDS             71762..73417
                     /gene="mltG"
                     /locus_tag="VVR39_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU6029769.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPAIETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            73488..73970
                     /gene="greA"
                     /locus_tag="VVR39_000214"
     CDS             73488..73970
                     /gene="greA"
                     /locus_tag="VVR39_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU6029770.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        22604 a        13666 c        16807 g        21026 t
ORIGIN      
        1 ttactgcttg tcaatctttt cttttctctc tcactttggc tctttacaga ttccgtttta
       61 tttgtagttg ctatgtctat tttgatgact tgctatggag ctggtttttc tttgattcca
      121 gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg ttatatttta
      181 acagcttggg caatggctgg tttagcggga cctattttat tagcagagac ttataaaatg
      241 gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat cgccttggct
      301 ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt
      361 tctgtagaaa tggggctatc ttttgctctg gtcttgtgtt atactagata ggttgcaaag
      421 aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta gttatatgaa
      481 aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg caccaccttt
      541 agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt gctagcagaa
      601 attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat tcctttggcc
      661 cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac tgcagccttt
      721 ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc cttggtcatc
      781 gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt tggtcgtagt
      841 aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca aattaaggct
      901 cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga cttgattaaa
      961 cgcaaggcct tgaaattaca aaacattgaa acccttatcc ttgacgaagc ggatgaaatg
     1021 cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc tgagaaccgt
     1081 caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg tgttcagttt
     1141 atgaaagccc ctgaacatgt caagattgcg gctaaggaat tgacaacaga attggttgac
     1201 cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg tctcatggat
     1261 gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt ggatgaattg
     1321 actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga cctagaccaa
     1381 aacaaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt tttggttgcg
     1441 acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta caactacgat
     1501 attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag
     1561 tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca aatcattgaa
     1621 aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa
     1681 tcaaaaaaac aggtggctct caagaaaatc gaacgtgatt ttgcagatga aaccattcgt
     1741 gccaactttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt tactccagaa
     1801 gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct tccagaagtg
     1861 gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt cggtggtaaa
     1921 gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc
     1981 aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt tgataaggaa
     2041 aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc
     2101 tttgttattc gtaacaaagg cgataaataa gaaaaagcgg ttcaaaatga atcgcttttt
     2161 tatataagga gaccgaatgt gaaaagacaa ataaaattac tatattatct tttataatgt
     2221 tatgatacac aaaaataggc aacttgtcaa tagaaaagga acaatttaat taaaaatatt
     2281 ctggttttta attaaattgt aagtcaatgc aagtcaataa ggaattttca gataattatt
     2341 gaaaaagaga cgtttttatg ttataatgat agcgattaaa ttcgaggtga aaaatggcac
     2401 atttattaga aaaaactaga aaaattacat caattttgaa acgctcagag gagcagttgc
     2461 aggatgagct cccttacaac gctattacgc gtcagttagc ggatattatt cattgcaatg
     2521 cctgcattat caatagtaag ggacgtctgc ttggctattt tatgcgttat aaaacaaata
     2581 cagatcgcgt agagcaattc ttccaaacta agattttccc agatgactac gttcaagggg
     2641 ctaatatgat ttacgaaaca gaagcaaact tgcctgttga gcatgatatg agtattttcc
     2701 ctgttgagag tagagatgat tttccagatg gcttgacgac tattgcaccg attcatgtat
     2761 cggggattcg ccttggttct ttgattattt ggcgtaatga taaaaaattc gaagatgagg
     2821 acttggttct tgttgagatt gccagtaccg ttgttgggat tcagcttctt aacttccaac
     2881 gtgaagaaga tgagaaaaat attcgtcgtc gtactgctgt caccatggcg gtcaataccc
     2941 tttcttactc cgaactccgt gctgtttcag caattttagg ggaattaaat ggaaatgaag
     3001 ggaagttgac tgcgtcagtg attgcagatc gtatcggaat cactcgctct gtgattgtca
     3061 atgctcttcg taaacttgag tctgcgggga ttattgaaag tcgctcactt ggaatgaagg
     3121 gaacctatct taaggtcttg atttcagata tttttgaaga agtgaagaaa agagattact
     3181 aatgacaaag gctttaattt cgattgatta tacagaagat tttgttgctg atagtgggaa
     3241 gctgacagca ggtgctccag ctcaggcgat ttcggatgcc atcagcaagg taactcgatt
     3301 agcttttgaa cgaggagatt atatcttctt tactattgat gctcatgaag aaaacgattt
     3361 tttccatccg gaaagtaagt tatttcctcc tcataatctg attgggacga gtggacggaa
     3421 tttatatgga gatttgggga tcttttatca agagcatggt tcagacagtc gtgtcttttg
     3481 gatggataaa cgccattact cagctttttc agggactgac ctagatattc gtttgagaga
     3541 gcgtagagtg tctaccgtta tcttaacagg tgtcttgacg gatatctgtg tcctacatac
     3601 agctatagat gcctataatc taggatatga catcgagatt gttaaaccag ctgttgcttc
     3661 tatctggcct gaaaatcatc aatttgccct aggtcatttc aaaaatacac tcggagctaa
     3721 gttagtagat gaaaatctaa atgaactttc tgagtaacct ggttggtgaa aatgaaaaaa
     3781 tttgaaaaaa agtgttgaca agcatcccaa aagttgatat actagtaaag taatcgatgc
     3841 ggggatggcg gaattggcag acgcgcagga ctaaggatcc tgtgaccgct ttaggtcgtg
     3901 agggttcaag tccctctctc cgcataggaa aagagttagc taaagctagc tcttttgtat
     3961 ttctctaaaa aattagaatc cagtcaaatg tagtggagaa tcagcgaaaa tatgggaaaa
     4021 ctgatccttg tttctgcttt tgtcatagaa gaataataaa gattatcttc ttcaaattct
     4081 ccgatattct ctaaagtttt gtgcaagttg cacagaactt ttttattttt ttggtcatct
     4141 tgccatagaa atataaagcg ttttcatcta taatataatt atcaaaagac aaaaggagtt
     4201 cacctcatgg tagaattgaa tcttaaaaat atttacaaaa aatatccaaa cagcgaacac
     4261 tattcagttg aagatttcaa cttgaacatc aaagataaag aatttatcgt tttcgtagga
     4321 ccttcaggat gtggtaaatc aactacactc cgtatgattg ctggtcttga agacatcaca
     4381 gaaggtactg catctatcga tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat
     4441 atcgccatgg tattccaaaa ctacgctctt tacccacaca tgactgttta tgacaacatg
     4501 gctttcggtt tgaaattgcg taaatacagc aaagaagaca ttaacaaacg tgttcaagaa
     4561 gcagctgaaa tacttggatt gaaagaattc ttggaacgta aaccagctga cctttcaggt
     4621 ggtcaacgtc aacgtgttgc catggggcgt gcgattgtcc gtgatgcgaa agtattcttg
     4681 atggacgaac ctttgtcaaa cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc
     4741 gctaaaattc accgtcgtat cggagctaca actatctatg taactcacga ccaaacagaa
     4801 gcgatgacac ttgcagaccg tatcgttatt atgtcagcta ctaagaaccc tgctggtaca
     4861 ggtactatcg gacgtgtaga acaaatcggt actcctcaag aagtttacaa aaatccagtt
     4921 aacaaatttg ttgcaggatt catcggaagc ccagctatga atttcatcaa cgtgaaattg
     4981 gttggtagcg aaattgtttc tgacggtttc cgtttgaaag tgccagaagg agcattgaaa
     5041 gttcttcgtg aaaaaggcta cgaaggaaaa gaattgatct ttggtatccg tccagaagac
     5101 gtgaatgcag aacctgcttt ccttgaaaca ttcccagact gtgttgtaaa agcgactatc
     5161 tctgtatcag aactgcttgg ttcagaatct cacctttact gccaagttgg taaagacgag
     5221 tttgttgcaa aagttgatgc tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga
     5281 tttgacttga acaaagcaca cttcttcgat gtagaaactg aaaaaacaat ttactaaaat
     5341 aaataaaatt caaaacacta caagaaaaga tatctcttta tcaattgtag tggagagata
     5401 tcagttaatc tagggagaga aacaaaatgc ttctctcctt tttgctaggg aagtcatatt
     5461 atgcatctat attgtgatgc tctttaatac tcttcgaaaa tctcttcaaa ccacgtcaac
     5521 gtcgccttgc cgtacgtatg attactgatt tcgtcagttt tatctgcaac ctcaaagatg
     5581 tactttgagc agcttacggc tagtttccta gtttgctctt tgatttccat tgagtattat
     5641 ttgtgggtac catctacaag tgaagctata tgcgtaaact acgtgagcaa ttgaattcga
     5701 actagagagg taataataaa tttatgctat agttatggtg acttgtatgc ttttgattct
     5761 agtttatcaa ataatagatt agaattgtca gataatatca ttttgtgtta taatgaagaa
     5821 aaaacagagg tgtgcaaatg tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa
     5881 aacgcttacg tccaggtgga aagcgtgcca cagattggtt aattgcagaa ggaggatttt
     5941 caaaagaaaa gagaatacta gaggttgcgt gtaatagggg aactacagca attgagttgg
     6001 cacagcgttt tggttgcaag ataactgctg ttgatatgga tgctcaagct ttagaagtgg
     6061 ctaaaaaatc tgctggaacg gcaggtgttg ctcatttaat cagttttgaa agagcaaatg
     6121 caatgaaact tccttatcaa gatgctagtt ttgatattgt tataaatgaa gctatgctga
     6181 ctatgcaagc cgatcaagct aagaaaaaat gtgtaatgga atatctaagg gtattaaaac
     6241 ctggaggtct tctcttgaca catgatgtac ttcttaagga agctaaagag tctatcagac
     6301 aggaattatc acaagcaatt catgtaaatg taggtccttt aactcaagat ggttgggaac
     6361 aggtgatgat agaatcaggt tattgtgatg tgaaagcatt gactggtgaa atgacattaa
     6421 tgaaattatc gggtatgatt tatgacgaag gtttgctagg aactttgaaa atttgtgtaa
     6481 atgcttgtaa aaaggagaat agaaagcagt ttttaactat gtataaaatg tttgctaaga
     6541 ataaacagaa attgggcttt attgcgatgg ctagttataa atcgtcaaaa cgttagataa
     6601 ttattgaagt taacttttcc ttttttcttt cttaaaaaat atgctataat agagagtaaa
     6661 aaactttgaa agaaagaaaa agatgaattt aaaagattac attgcaacaa ttgaaaatta
     6721 tccaaaggaa ggcattacct tccgtgatat tagtcctttg atggctgatg gaaatgctta
     6781 tagctacgct gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg acatgatcgt
     6841 gggacctgaa gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg
     6901 ttttgcgcct gttcgtaagc caggtaaatt gccacgcgaa gttatttctg ctgactatga
     6961 aaaagagtac ggtgtcgata ccttgactat gcacgcggat gccattaagc caggtcaacg
     7021 tgttcttatt gtagatgacc ttttggcgac aggtggaact gttaaggcaa ctatcgagat
     7081 gattgaaaaa cttggtggtg ttatggcagg ttgtgccttc cttgttgaat tggatgaatt
     7141 gaacggccgt gaaaaaattg gtgactacga ctacaaagtt cttatgcatt attaatgaaa
     7201 acagtcccta gggctgtttt ctctacacta ggatataaaa atagactata actagttaga
     7261 gaaaaactat aattgaaaac tatatcttct tacagtataa taaaaggact aagtgtttga
     7321 gatttgtctt caaacatatg caattattcc tgaaagagta cagttaggag agggttatgc
     7381 cgattcgaat tgataaaaaa ttgccagctg ttgagatttt acggacagag aatatctttg
     7441 tcatggatga tcaacgtgct gcccaccaag atatccgtcc tttgaagatt ttaattttaa
     7501 atctcatgcc acagaaaatg gtcacagaga cccagttgtt gcgccacttg gctaatacac
     7561 ccctacaact ggatattgat tttctctata tggagagcca ccgttctaaa acaactcgtt
     7621 cagagcacat ggagaccttc tataaaactt ttcctgaagt caaggatgag tattttgatg
     7681 ggatgatcat cacgggtgct ccagttgagc atttaccatt tgaggaagtg gactattggg
     7741 aggaatttag acagatgctt gagtggtcta agactcatgt ctattcgacc cttcatatct
     7801 gttggggggc tcaggctggg ctttatctgc gctatggtgt agaaaaatac cagatggaca
     7861 gtaagctatc aggtatttat cctcaggaca ccctaaaaga gggtcacctt ctatttagag
     7921 gctttgatga tagctatgta tcccctcatt cacggcacac ggagatttct aaggaagagg
     7981 tcttaaacaa gaccaatctc gagattttat cagaaggacc tcaggttggg gtttctattt
     8041 tggccagtcg tgatttacga gaaatttata gttttggtca tttggagtat gaccgtgata
     8101 ccttggcaaa agagtatttt cgagatcgtg atgcaggttt cgacccacat attccagaaa
     8161 attactttaa agatgatgat gttaatcagg taccttgtct ttgttggtct tcatctgcag
     8221 ccctcttttt cagtaattgg gtaaaccatg cggtctatca ggagacgcct tttgattgga
     8281 gaaagataga agatgatgca tctgcatatg ggtatttata agaggaatta tgacatattt
     8341 agacgctttt aaatcaggta ccttggtttt accgagtgcc ctgctcttgc attttaagga
     8401 actctttcct tctagcgacg attttctggt ttggcaattt ttctatttgc aaaatacgac
     8461 aggcttagaa gaaatgtcgc caagccagat tgctgaaagg attggcaagg aaatttcgga
     8521 tgtcaaccag tccatttcta atctgacgga aaggggactg ctccagtatc gtactatcga
     8581 attaaatggc gaaattgaat tgctctttga tgctagtttg gccttggaac gtttggatga
     8641 cctgtttgga gcagttcgtt caagttcaga ccagctaaca cctcaaaacc agctcaagga
     8701 tttggtggaa accttccagc aggagttggg acgattgttg acgccttttg agattgagga
     8761 tttgaccaag acactaaagg aagatggaac cagtgctgac ttgattaagg aggctcttcg
     8821 tgaagctgtt ttgaatggaa aaccaaactg gaagtacatt caggcgattt tgagaaactg
     8881 gcgctatgaa ggaatcaaga gtgtggctca aattgaggcc aagagagcag aaagagaagc
     8941 aagcaatcct cagttgacac aggtatctgc agatttcata aatgccatgg atctctggaa
     9001 ggattaatcc atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg tgtataattg
     9061 tgatagaata aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat
     9121 ttatcgctgg taactggaaa atgaacaaaa atccagaaga agctaaagca ttcgttgaag
     9181 cagttgcatc aaaacttcct tcatcagatc ttgttgaagc aggtatcgct gctccagctc
     9241 ttgatttgac aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt gctgctcaaa
     9301 actgctactt tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa gttttgaaag
     9361 aaatcggtac tgactacgtt gttatcggtc actcagaacg ccgtgactac ttccatgaaa
     9421 ctgatgaaga tatcaacaaa aaagcaaaag caatctttgc gaacggtatg cttccaatca
     9481 tctgttgtgg tgaatcactt gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg
     9541 ctcaagtatc tgctgcattg gctggattga ctgctgaaca agttgctgcc tcagttatcg
     9601 cttatgagcc aatctgggct atcggtactg gtaaatcagc ttcacaagac gatgcacaaa
     9661 aaatgtgtaa agttgttcgt gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca
     9721 aagttcgtgt tcaatacggt ggttctgtta aacctgaaaa tgttgcttca tacatggctt
     9781 gcccagacgt tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa agcttcttgg
     9841 ctttgcttga ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa cagcattcag
     9901 atgtctgtta cattttttat aggagagaaa gattgaaaac aaaaattgga ttagcaagta
     9961 tctgtttact aggcttggca actagtcatg tcgctgcaaa tgaaactgaa gtagcaaaaa
    10021 cttcgcagga tacaacgaca gcttcaagta gttcagagca aaatcagtct tctaataaaa
    10081 cgcaaacgag cgcagaagta cagactaatg ctgctgccca ctgggatggg gattattatg
    10141 taaaggatga tggttctaaa gctcaaagtg aatggatttt tgacaactac tataaggctt
    10201 ggttttatat taattcagat ggtcgttact cgcagaatga atggcatgga aattactacc
    10261 tgaaatcagg tggatatatg gcccaaaacg agtggatcta tgacagtaat tacaagagtt
    10321 ggttttatct caagtcagat ggggcttatg ctcatcaaga atggcaattg attggaaata
    10381 agtggtacta cttcaagaag tggggttaca tggctaaaag ccaatggcaa ggaagttatt
    10441 tcttgaatgg tcaaggagct atgatgcaaa atgaatggct ctatgatcca gcctattctg
    10501 cttattttta tctaaaatcc gatggaactt atgctaacca agagtggcaa aaagtgggcg
    10561 gcaaatggta ctatttcaag aagtggggct atatggctcg gaatgagtgg caaggcaact
    10621 actatttgac tggaagtggt gccatggcga ctgacgaagt gattatggat ggtactcgct
    10681 atatctttgc ggcctctggt gagctcaaag aaaagaaaga tttgaatgtc ggctgggttc
    10741 acagagatgg taagcgctat ttctttaata atagagaaga acaagtggga accgaacatg
    10801 ctaagaaagt cattgatatt agtgagcaca atggtcgtat caatgattgg aaaaaggtta
    10861 ttgatgagaa cgaagtggat ggtgtcattg ttcgtctagg ttatagcggt aaagaagaca
    10921 aggaattggc gcataacatt aaggagttaa accgtctggg aattccttat ggtgtctatc
    10981 tctataccta tgctgaaaat gagaccgatg ctgagagtga cgctaaacag accattgaac
    11041 ttataaagaa atacaatatg aacctgtctt accctatcta ttatgatgtt gagaattggg
    11101 aatatgtaaa taagagtaag agagctccaa gtgatacagg cacttgggtt aaaatcatca
    11161 acaagtacat ggacacgatg aagcaggcgg gttatcaaaa tgtgtatgtc tatagctatc
    11221 gtagtttatt acagacgcgt ttaaaacacc cagatatttt aaaacatgta aactgggtag
    11281 cggcctatac gaatgcttta gaatgggaaa accctcatta ttcaggaaaa aaaggttggc
    11341 aatatacctc ttctgaatac atgaaaggaa tccaagggcg cgtagatgtc agcgtttggt
    11401 attaagcgat gatttgaaag agggatgtga tagtagcacc ctctttttct ttgttttatg
    11461 atagttcatc ctcgagtaaa ttcaagatct tgctcggaaa tgaagcttat atagtagatt
    11521 gaatatagac aaataccttg tgattggtaa aacattttag aaattcattt acctttccta
    11581 atcgacttgg tttcatctta tttcaatcta ttatagtatt ggggaatttc ttcaaaccac
    11641 atcagcttgg tcagttctac ctgcgacctc aaaacttgtg ctttggtcaa gctgggttta
    11701 gtttcctagt ttgctgatgg atttccattg actataagca tccaaccctc tttttgtctt
    11761 ctaaagaatt cttaaattat cagtctattg caacttttct catataagtt ctttgtcttg
    11821 ctattggttt tccttagtag tatactaagg tagtaatcat taagaagtgg ttacaaaaaa
    11881 taatgaatga ggtaaagaaa atggtagaat tgaaaaaaga agcagtaaaa gacgtaacat
    11941 cattgacaaa agcagcgcca gtagcattgg caaaaacaaa ggaagtcttg aaccaagctg
    12001 ttgctgattt gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc
    12061 gtggtttcct tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gacggtcaat
    12121 tggatgaaat cagcgaacgc ttgattacac tcggtggaag cccattctct acattgacag
    12181 agttccttca aaatagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa
    12241 gcttggaacg tgttcttgtt atctaccgtt acttgtcaga acttttccaa aaaggtttgg
    12301 atgtcactga tgaagaaggt gacgatgtaa caaacggtat ctttgcaggc gctaaaactg
    12361 aaacagataa aacaatttgg atgcttgcag ccgaacttgg acaagcacct ggtttgtaag
    12421 aaataaggaa acatagataa atctgtagga aatttcttac agattttttc tattttgtaa
    12481 gctattccaa accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg
    12541 atggaagcat gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg
    12601 gtaaggaaaa tcgtctgcct tggcatttgc cagcagaatt gcagcacttt aaagaaacaa
    12661 ctctgaatca tgctatcttg atggggcgtg tgacctttga tgggatgggg cgtcgcttgc
    12721 ttccaaaacg ggaaaccttg attttgacgc gtaatccgga agaaaagata gatggggttg
    12781 ctacttttca ggacgtccag tctgttcttg actggtatca ggctcaagaa aagaatctct
    12841 acattatcgg tgggaagcaa atttttcagg cttttgaagc ttaccttgat gaagtgattg
    12901 tcactcacat tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt
    12961 ctctttttga gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt
    13021 ttaccatcca ataccgcaag agaaaggaag tttaatggaa cggagtttat ttggtctatt
    13081 cacggctttt ctgtgtttca tctgctttct ggcaggagca caagcttttc gtaaaaagcg
    13141 ttacgggctt tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca
    13201 tgctttttac atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt
    13261 ctacaaatag aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag
    13321 aagtacaaaa aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag
    13381 ctcaggaaat cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc
    13441 caaaaccaat tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca
    13501 agcgtgcctt ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac
    13561 gcgaagagtc agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg
    13621 gttcagggaa aactttcctt gcccagacct tggctaagag cttgaatgta ccttttgcta
    13681 ttgcggatgc gacagctctg acggaggctg gttatgtggg tgaggatgtg gaaaatatac
    13741 tcctcaaact cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct
    13801 atgtggatga aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg
    13861 tttctggtga aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg
    13921 taccgcctca aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa
    13981 atatcctctt catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc
    14041 tgggtgaaaa agtcatcgga tttggtcaaa acaataaggc gattgacgaa aacagctcat
    14101 acatgcaaga aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg
    14161 gacgcttgcc tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct
    14221 tgaaagagcc aagaaatgcc ttggtgaaac aataccaaac cttgctttct tatgatgatg
    14281 ttgagttgga atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga
    14341 agacaggggc gcgtggactt cgctccatta tcgaagaaac catgctagat gttatgtttg
    14401 aggtgccgag tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa
    14461 cggataaacc gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc
    14521 tgaaatcttg ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat
    14581 tgccctagca gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg
    14641 taagaatctc gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa
    14701 cattgatgac aagatgcgct ttgtggatgt gcctggttat ggctatgccc gtgtttctaa
    14761 aaaggaacgt gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct
    14821 ccgtgcggtt gtcagtctag ttgaccttcg tcatgacccg tcagcagatg atgtgcagat
    14881 gtacgaattt ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa
    14941 gattcctcgt ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga
    15001 cccaagtgac gatttcatcc tcttttcatc tgtcagcaag gcagggatgg atgaggcttg
    15061 ggatgcaatc ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata
    15121 aggccccaaa ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg
    15181 ctagcggtca agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag
    15241 aacagacaga gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact
    15301 ttgaccatgt tgtcaaaaca acttgtttct tgagcgatat gaacgacttt gttcctttta
    15361 atgaggttta ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag
    15421 ctcgtcttcc tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta
    15481 gttgaagttt ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac
    15541 aacttcactt ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt
    15601 ccttcgagga tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt
    15661 ttttgcagct ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc
    15721 gtagccgttc tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg
    15781 gtttggattt caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca
    15841 aggaaaccag acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt
    15901 tggaacgtga actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg
    15961 aactcactcc acgtgagctg cgcaaaaccc ttgcagagca gttttcagac caagaacaag
    16021 ctcagtcttt ccgtatcgaa gtcatgtctt tcggatttaa gtatggaatc ccgattgatg
    16081 cggacttggt ctttgatgtc cgtttcttgc caaatcccta ttatttacca gaactgagaa
    16141 accaaacggg tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag
    16201 acttttatca acatttattg gccttgattg agccgattct gccaagttac caaaaggaag
    16261 gtaagtccgt tttgaccatt gccatgggat gtacgggtgg acaacaccgt agtgtggcat
    16321 ttgctaaatg cttggcgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg
    16381 acaaagaccg cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat
    16441 tggtggaggg actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat
    16501 cgcagctatc gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat
    16561 gcaacagttg acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc
    16621 taagttttat gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg
    16681 ccatccattg ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa
    16741 tgccatgcag ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga
    16801 ccatcctttg acccttcatg cagtctttca ggatgggaca gaagtggttg gagagagtca
    16861 tattgtagac catcgaggca taattgacaa tgtctatgtg accaatgccc taaacgatga
    16921 tacgcctctg gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct
    16981 agggccaggt tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg
    17041 ggctcttttg gaaaccaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg
    17101 ggagacggaa cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg
    17161 cccttttatc gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc
    17221 caaccgtttt gatgaatact tggtgcaagt ggaacacgat tttgtaggtc tttgtaagca
    17281 agtttcgcgc gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga
    17341 tggagatttg attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca
    17401 gtagcagtaa aagaagaaat cctgggccaa caccatctga gctggcatga attatctgcc
    17461 attatcaaaa tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg
    17521 acagaaaatg ccaaactggc ccgtcacctc tatgagtcct ttctccattt ctatgaaatc
    17581 aaatctgaaa ttcgtcacca ccaacggagc aatcttcgca agaatcgcgt ctataccgtt
    17641 tttacagatg aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt
    17701 agcctggaaa caggtattga tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat
    17761 ctctgtggcg ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag
    17821 ttggaaatca gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag
    17881 tttttactgg atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga
    17941 gcagaagaca ttatggactt cttgatagta atcggagcca tgcaggcacg tgatgatttt
    18001 gagcgggtta agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag
    18061 acagctaata tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa
    18121 atcaaagata tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg
    18181 agaattcagc acccagacta ctctatccag cagttagcag atagtctcag cacccctctg
    18241 accaaaagtg gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa
    18301 aaccacgaat cctatgtgac tcgtggttct tttttataaa ctagtagagt gttttggttg
    18361 tactttttgt tcagggtcaa tgtacttgat agcgttgttg acagcagttg gagcttctcc
    18421 gaggcctgtc gcaatcagat caatttttcc gtcatagtag cagcagtcac cgatagcata
    18481 gatacctgct tggctggatt cctgtttgct gttgacgata atcttgtgac ggttgaggtc
    18541 gagcccccag tttttaaggt taccgacaga agatttgaaa ccatagttga caaagaggtg
    18601 gtctaggtca atggtttcag tttcatcaga tttgactttt gtgatttcaa gtttagcaag
    18661 tgtttttcca tttccaagga gttggctagg ggcgaatggt gtcttgatgg ttacagatga
    18721 ttcttgcaag gcttgaacac tgtgttccaa ggcacggaaa ttatctctgc ggtgaacaag
    18781 ggtagttggt gcgatttttt caaaagccaa agcccaatcc acagccgagt ctcccccacc
    18841 aagaatcgtc actttcttac cagcgtattg ctgaatgtta gaaacgtggt agtggatatt
    18901 ttcatagccc tcaacacctt caagttccag cggacgtggt ttgaaggcac cgccacccat
    18961 agcgatgatg actgttttag tcaggtgact tcctttagaa gttgtgatgg caaattcttc
    19021 ttcttgtttg tcaatctcaa gaaccgtttc attgagatga ataggggtat caaatccatt
    19081 tagctgttca atcaagcggt tagtcaactc ttctccagtc aggtttggga agcctggtac
    19141 gtctaggatt tccttttcag ggtagagaat agcaggttgt ccacctagct ggggaagaga
    19201 gtcgatgatt tgaaccttgg cttggcgtag gtgggcataa aaggctgcaa aaagcccgac
    19261 aggaccacca cccacaatgg taatatcata gagttgagac atagtttctc ctttgttttt
    19321 tctagtcagt ttattttatc atatttttgt tcaatgtaaa atggactagg atagggaaaa
    19381 aaatgccaga aaatggtata ataggacgaa agtgttttga tagggaggat atcagggatg
    19441 aattttcaac aattatccaa tctgcaatat tggaccagtt tgtttgcaag tccatggacg
    19501 atagctatca atctgattga tattttgatt gttgcttata ttttatacca ttttacaaaa
    19561 gctattgcag gaaccaagat tatgattttg gtacgtggag ttttggtgtt tattttagct
    19621 caaatccttg caaatatgat tggtttgact acgatttctt ggttaatcaa tcaaattatt
    19681 acttatgggg ttattgcggc ggttgttatc ttctctccag agattcggac tggtttggaa
    19741 cgtttgggaa gagcgacaga tttcttttcc aatgccccta ttagtgctga ggaacagatg
    19801 attcgtgcct ttgttaagtc tgttgaatac atgagtcctc gtaaaatcgg ggccttggtt
    19861 gctattcagc gtgtacgtac cttgcaggag tatatttcga caggaattcc cttggatgct
    19921 aagatttctg cagaacttct cattaacatt tttattccca acactcccct acatgatggt
    19981 gcggtgatta tcaaagaaga acgtatcgct gtgacgtctg cctatctgcc cttgacaaaa
    20041 aacacaggga tttccaagga atttgggact agacaccggg cggctatcgg tttatcagaa
    20101 gtctcagatg ccttgacttt tgtcgtatca gaggaaacgg gaggaatttc gataacctat
    20161 aatggaaggt ttaagcacaa cctaacactt gatgaatttg aaacagaatt acgtgaaatc
    20221 ttacttccaa aagaggaagt gggtcttagt tttaaagaac gattgctagg aggatggaaa
    20281 catgaaaaaa aatagtttat atatcatatc ctcactcttt tttgcttgtg tcttatttgt
    20341 ctatgctacg gcgacgaatt ttcaaaacag taccagtgct aggcaggtaa aaacggaaac
    20401 ctatactaat acagtaacaa atgtccctat tgacatacgc tataatagtg ataagtattt
    20461 tattagcggt tttgcttcag aagtatcagt ggtcttgact ggtgcaaatc gcctatcgct
    20521 agctagtgaa atgcaagaaa gtacacgtaa attcaaggtt actgctgacc taacagatgc
    20581 cggtgttgga acgattgaag ttcctttgag cattgaagat ttacccaatg ggctgaccgc
    20641 tgtggcgact ccgcaaaaaa ttacagtcaa gattggtaag aaggctcaga aggataaggt
    20701 aaagattgta ccagagattg accctagtca aattgatagt cgggtacaaa ttgaaaatgt
    20761 catggtgtca gataaagaag tgtcgattac gagtgaccaa gagacattgg atagaattga
    20821 taagattatc gctgtcttgc caactagcga acgtataaca ggtaattaca gtggttcagt
    20881 acctttgcag gcaatcgacc gcaatggtgt tgtcttaccg gcagttatca ctccgtttga
    20941 tacaataatg aaggtgacta caaaaccagt agcaccaagt tcaagcacat caaattcaag
    21001 tacaagcagt tcatcggaga catcttcgtc aacgaaagca actagttcaa aaacgaatta
    21061 aaaatagaaa aggattttat aacaatgggt aaatattttg ggactgatgg agtccgtgga
    21121 gaagctaacc tagaactaac accagaatta gcctttaaac taggacgttt tggaggctat
    21181 gttcttagtc aacatgaaac ggaagcgccg aaagtctttg taggacgtga cacacgtatt
    21241 tcaggggaaa tgctggaatc ggccttggtg gcaggtctcc tttcagtagg gattcacgta
    21301 tacaaacttg gtgtccttgc aacaccagca gtagcttact tggttgaaac tgaaggagca
    21361 agtgccggtg tcatgatttc tgctagccac aacccagccc ttgataacgg aatcaagttc
    21421 tttggcggtg atggcttcaa actagatgat gaaaaagaag cagaaattga agccttgcta
    21481 gatgctgagg aagacactct tcctcgtcca agtgcagaag gcttaggaat tttggtagat
    21541 tatccagaag gcttgcgtaa gtatgaagga taccttgttt caactggaac tcctcttgat
    21601 ggaatgaagg ttgccttgga tacagctaat ggagcagctt ctaccagtgc ccgtcaaatc
    21661 tttgcagacc ttggtgccca attgacggtt atcggggaaa caccagacgg tcttaacatc
    21721 aaccttaatg ttggttcaac acatccagaa gcccttcaag aagtggtcaa agaaagtggg
    21781 tcagctattg gtttggcctt tgatggagac agtgatcgct tgattgctgt tgatgagaat
    21841 ggtgacatcg tcgatggtga caagattatg tacatcatcg gaaaatacct ttctgaaaaa
    21901 ggacaattgg ctcaaaatac aattgtgaca actgttatgt ctaaccttgg tttccacaag
    21961 gccttgaatc gcgaaggtat taacaaggca gttactgcag ttggtgaccg ctacgttgtt
    22021 gaagaaatga gaaaatcagg ctacaacctt ggtggtgaac agtctggtca cgttatcttg
    22081 atggattaca ataccacagg tgatggtcaa ttatcagcag ttcaattgac taaaattatg
    22141 aaggaaactg gtaagagctt atcagagttg gcggcagaag taacgattta tccacaaaaa
    22201 ttagttaata tccgagtgga aaacgtcatg aaggaaaagg ccatggaagt gccagctatc
    22261 aaggccatca tcgagaagat ggaagaagaa atggcgggga acggccgtat ccttgttcgt
    22321 ccaagtggaa cagagcccct cttgcgtgtt atggcagaag cgcctacaac agaagaagtg
    22381 gactactatg ttgataccat cacagatgta gttcgtgctg aaattgggat tgactaaatc
    22441 ctagaaaact agatgaaaat aaaaaattat ggtacaatag cttataatat tgtagccgat
    22501 ggagaaagac atgaatctta aacgtgaaca agaatttgtt agtcagtatc attttgatgc
    22561 gcgtaatttt gaatgggaaa atgaaaatgg agctcctgaa accaaggtgg atgtgaattt
    22621 ccaattgctc caacatgacc aagaaaatca agtgacttcc ttgattgtca tcttgagctt
    22681 tatgattgta tttgataagt ttgtcattag tggaacaatc tcacaagtaa accatatcga
    22741 tggccgtatt gtcaatgaac caagtgaatt gaaccaagaa gaggtggaaa ccttggctcg
    22801 tccatgtttg aacatgctca atcgtttgac ttacgaagtg actgaaattg cattagactt
    22861 accaggaatt aatttggagt tctaatatga aattagctgt tttcacagat tcctctgctt
    22921 atctcagtgc agagaccttg caaagagaag acttgtttgt cttggatatt cctgtcaata
    22981 ttgatggtga ggaatatgtc gaaggcatca atctgtctgc tgaggaattt taccaaaaaa
    23041 tggctcaggc ttctgaattg cctaagacca gtcaaccaag tattgccaag ttagatgaga
    23101 tcttaacttc gctcaaagaa caaggctata cacatgcctt ggggcttttc ctatcttctg
    23161 gaatttcagg tttttaccaa aatatccagt atatggtcga tgactatgag ggcttaacca
    23221 ttgctttccc agacactttg attacaagtg ctcccctagg catcatggtt gaaagcgtct
    23281 ttaattggcg tgatcagggc gatgattttg ccagcattca ggataagcta gccattcaaa
    23341 tcagccgtac gtcagccttt atcatggtag atgacttgga tcatttggta aaaggtggac
    23401 gcctttcaaa tggggctgcc attttgggca atttgcttag cattaagcca atcctttatt
    23461 ttaacgatca aggtatgatt gaagtttacg aaaaagttcg tactgaaaag aaggccacca
    23521 agcgcttaat tgaaattatc aaggaaacaa cggcttcagg tcaataccgg gtcattgtca
    23581 ttcatgggaa tgctcctgaa aaggctgaag aattgcgtca gcatttgctt gattttggct
    23641 tgggttcgga tgtttcactt gctacatttg gtagtgtcat tggaacgcac ctaggatcag
    23701 gaagtattgc tctgggttat attccagtga tttagttggc gcttctaggc tagttaagat
    23761 gccttgtatc ttagaaattg aacacggact acctgcctct tgaaaaaaga tgcctgtctt
    23821 gcctttcgtg gaaagtcagt gccattccct atttttcaga ggcagctaag gtcctttgta
    23881 tcttgataat tgaacacgcc tggaaccctg tgtgaaaaag atagttcttc caagaagtag
    23941 acacttcttg attggaattc ctattttcac tttgtgttct tacggacttt gtatcttaga
    24001 caggagtaga gatgagtatt cgagtaatta ttgccggttt taagggaaag atgggccagg
    24061 ctgcttgtca gatggtattg actgatccag acttggactt ggtagcagtt ttggatcctt
    24121 ttgagtctga gtcagaatgg cagggtattc ctgttttcaa ggataaggct gatttagctg
    24181 gttttgaagc ggatgtctgg gtagatttta ctactccagc tgttgcctac gaaaatacac
    24241 gttttgctct tgaaaatggc tttgctccag tagttggaac gactggtttc acgagtgaag
    24301 aaattgcaga gctaaaagaa ttttctcgtg cccaagactt gggtggcctg attgccccta
    24361 actttgcctt gggtgctgtc ttactcatgc aatttgcgac gcaggctgcc aaatatttcc
    24421 caaatgtgga gattattgag ctccatcatg acaagaaaaa ggatgctccg agtggaacag
    24481 ccattaaaac agctgagttg atggcagagg ttcgagagtc aattcagcaa ggtgcagcag
    24541 atgaggaaga gctgattgct ggtgctcgtg gtgctgactt tgatggtatg cgcatccact
    24601 cagttcgttt gccaggcttg gtagctcatc aggaagtcat ctttggcaat cagggagaag
    24661 ggttgaccct ccgtcatgac tcctatgatc gcatctcctt catgacagga gtcaatttgg
    24721 gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg attagaacac ttattatgag
    24781 attaacgcaa atgccttctg aatttcagaa ggctttacca gtattagaaa aaattaaaga
    24841 agcaggcttt gaggcttatt ttgttggggg ctctgttcga gatgcccttc tccatagccc
    24901 tatccacgat gtggatattg cgacgtcttc ttatccagaa gagaccaagc agatttttcc
    24961 gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg gtcttagatg gggatgagga
    25021 gtatgaggta acaacctttc ggacagagga tgtctatgtg gactatcgca gacccagtgc
    25081 ggtttccttt gtacgatcgc tagaagaaga cctcaaacgc cgtgatttca cagtcaacgc
    25141 ctttgccttg gatgagacag gagaaatcgt tgacttgttc catggtttag aagatttgga
    25201 aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt ttcaacgaag atgctttacg
    25261 gattatgcgt ggtttccgtt ttcaggctag tcttggtttt gcacttgagc cagaaacatt
    25321 taaagctatg aagaccttga cgccgctttt ggagaaaatt tctgtagagc gtaccttcgt
    25381 cgagtttgat aaactcttgc tggctccatt ttggagaagg ggcttggctt ccatgattga
    25441 gagtcaagct tatgactatc tccctgatat ggcatctagc caggacaagc tcaacagact
    25501 gtttgatttg gagactgatt ttacttttga atcctctgaa caagcctggg cggctttact
    25561 atgggctttg gagattgaaa atgcgcagtc atttttgaaa tcttggaaga cctcacgcca
    25621 gtttgccaag caagttcagg atttgctgat tattttggct ctgcgtgaaa atggagaatt
    25681 gagcaagcga gattgttatc gctttgacat agatttgctt ttacaggctg aaaatcttcg
    25741 tcaagctcaa ggaaaagaag tcaacccaca agccatcaca gaaaaatacc aaagcttgac
    25801 tatccatgac aagaaagaga ttcagattaa tggcggtatt ttgatcaagg aatatggcta
    25861 tcagccaggc ccagacttgg gagagatttt aacagagatt gagtttgcca ttgtcgatgg
    25921 agaattggag aataatcgtg aagccatcca tgcttacctg agggagaaaa aatgagtgat
    25981 tttatcgttg aaaaactaac taaatccgtt ggtgacaaga ccgtttttag ggatatttcc
    26041 tttattatcc atgacttaga cagaattggt ctaatcggtg tcaatgggac tggcaagacc
    26101 acccttttgg acgtcctttc tggtgtttct ggatttgatg gggatgtcag tcctttttca
    26161 gctaaaaatg attaccagat tggttacttg actcaggatc ctgattttga tgatagaaag
    26221 acagttttgg atacggttct atctagtgaa ctcaaggaaa tccagctcat tcgtgagtat
    26281 gaattgatta tgctcgacta tagtgaggac aagcaggcgc gtttggaacg tgtcatggca
    26341 gagatggact ctctccaagc ttgggaaatc gagagtcagg tcaagaccgt tcttagcaaa
    26401 ttgggcattc aagacttatc tactcctgtt ggggaattgt caggtggtct gagaagacgg
    26461 gtacagttgg cacaagtctt acttggcaac cacgatcttt tgcttttgga tgagccgacc
    26521 aaccatctgg atattgcgat tattgagtgg ctgaccctct ttttgaaaaa ttctaagaag
    26581 accgtccttt ttatcactca cgatcgttat ttcttagacg ctttgtcaac acggattttc
    26641 gagttggagc gagcaggctt gacagaatat cagggcaatt accaggacta tgttcgcctt
    26701 aaggcagaac aggacgagcg cgatgcagct ctacttcata aaaaagaaca actctacaaa
    26761 caagaactgg cctggatgcg cagacaacca caggcacgtg cgaccaagca acaagctcgt
    26821 atcaatcgtt tccatgatct gaaaaaggaa gtttcaggca gtagtgctga gacagacttg
    26881 actatgaact ttgaaaccag tcggattggg aagaaagtca tcgagtttca ggatgtttcc
    26941 tttgcctatg aaaataagcc cattttgcaa gattttaatc tcttagttca ggctaaagac
    27001 cgtattggaa ttgttgggga caatggtgtt ggaaaatcaa ccctacttaa cctgattgca
    27061 ggaagtcttg agccgacagc aggacaagtt gtgattgggg aaactgttcg catcgcctat
    27121 ttctctcaac aaattgaggg tttggatgaa agcaagcgtg tgatcaatta cctgcaggaa
    27181 gtggcagagg aggtcaagac cagtggtggt tctacgactt ccatcgctga gttgctggag
    27241 caattcctct tcccacgttc gacgcatggg accttgattg agaaattgtc agggggtgag
    27301 aaaaaacgtc tttatctcct caaactgctt ttggaaaaac caaatgttct tcttttagac
    27361 gagccaacca atgacctaga tattgcaact ttgacagtct tagagaattt cttgcaaggt
    27421 tttgcaggtc ccgttttaac agtcagtcac gaccgctatt tcttggataa ggtagcgacc
    27481 aagattctcg cttttgagga tggcaagatt cgtcctttct ttggtcatta caccgactat
    27541 cttgatgaaa aagcttttga aacagatatg gccaatcaag tgcaaaaggc cgaaaaggaa
    27601 aaagtggtca aggttcgaga agacaagaaa cgcatgacct accaagaaaa gcaggagtgg
    27661 gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta tcgctgctat tgaagaggaa
    27721 atgcaggcta acggctctga ctttggtaag ctggctactc tccaaaaaga attggatgag
    27781 aaaaatgaag cactccttga aaaatacgaa tgctatgagt atctcagtga atttgatagt
    27841 taagactatt cgaaaatcaa agtgcaaact atgtcggctt cacattgccg actcaagtac
    27901 agcctgtgac cggcttccta atttgcactt tgatttttat tgagtataaa agaatagaaa
    27961 aatcccgtct catgaaagga tttctctatt cttttttggt ttcttgatga aagatatttt
    28021 gccaggtttc gtggcgacgc cagatactgg tatggatgat accatctaac tcatagcaga
    28081 tgagtttggt tttttgactg atggaagtaa tttgaatgtc cttgatagca gaatttaact
    28141 cttttttggt cttataagcc tctttatcca tctgctctcc atcttggcga atatagacaa
    28201 aatcatcagt caagagttct tctagttggt ttccttggtc aatcaattgt tcacgcataa
    28261 gcaatttttt atagacattg tctaaaattt catcctcagg gataggtgct ggttcgatat
    28321 ggacatcggt atcaaagacg ccaaaacgct cctccagcat agactcgacc tgatccgcga
    28381 tttcatggct ttcaaaaaca gacaagtcag gattcatctc tagtgtaata tccaggtaga
    28441 tgttgctacc gtaggtgcga cctctttgcg atttgacctt gctgattttg ggaatttcca
    28501 tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa gccatctgaa agactaaagg
    28561 aagactcgat gaagatatca taggcagtct tcaagataaa gaaagtgatg ataatagcaa
    28621 ccagtttatc cacaatcgga taattaaaac tactagctag gatggcaatg gcggttccaa
    28681 gtgaggtaac agcgtcagaa agattgtcct tagcagctgc cttcagcgcc ttggagttgg
    28741 atttcttact gaggcgagta ttgtagagat agaccacaaa cataatcgct gcagaaatga
    28801 ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc ccgactgaga atcttttgaa
    28861 tggtatctct tagaacatcg aaaccgacat agaacatgat gatagaagtg atcaagcttg
    28921 ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg gtctgcaggc tggcgcgcca
    28981 tccgaatccc gattaagagg gccacatttc caatgatgtc cgatacgtta ttaaaaccat
    29041 cggccaccaa actggatgaa tgaaggagat gaccagctgc taatttggct gcagacaaga
    29101 tcaaataggt cgaaatactg ataatggctc cacgctcagc taacttgaga tttgagatag
    29161 attgcttcat tcaacttcct ttctagtcac atagcattct accattatac tggttttcaa
    29221 ggaaaaattc aaataaggca gtttttactc tttgaaaact ccccaaaatt tggtataatg
    29281 gtactactca agggagtagc tggcagaaac ctgtgatagt gtcgtcattc cgaattttat
    29341 gctgaaaagt atgctttccg gccctatctt aaacagcgag acttgttatg attaacaggt
    29401 ctctttttgt ttgtcgtgaa aagatatgac agaaagagag tctgttttgc acacaatgtc
    29461 aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg ttttatactc agagccctga
    29521 agaggtcttg caggctgtgg atgcgaccga gcaaggtttg tcatcaagtg aggcggaaaa
    29581 gcgccttgcc gaatttgggc acaatgaact cgaagaaggc gagaaacgat caatcttggt
    29641 caaattcatc gagcaattta aggatttgat gattatcatc ctagttgcgg cagcaatctt
    29701 gtcagtcgtg acttctggtg gggaagatat cgcagatgcc attatcatcc tagctgtggt
    29761 tatcatcaac gctgcctttg gtgtttacca agaaggaaaa gctgaagaag ctattgaagc
    29821 cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt gatggacaca tggcagagat
    29881 tgactctaaa gaattggtac caggcgatat cgttgccctt gaagcaggtg acgtggtacc
    29941 agcggaccta cgtttgatag aagccaactc tcttaaaatt gaagaagcag ccttgacagg
    30001 tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt gcgacagatg ctggtattgg
    30061 tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc tatggtcgtg ggatgggtgt
    30121 tgttgtcaat acaggtatgt acactgaagt tggtcatatt gctggtatgc ttcaagatgc
    30181 ggatgagact gatacaccac tcaaacaaaa tttgaacaac ctttctaagg tcttgaccta
    30241 tgctatcttg gtcattgccc ttgttacttt tgtagtgggt gtcttcattc aagggaaaaa
    30301 tccacttggt gagttgttga cttctgttgc ccttgccgtt gcagccattc cagaaggact
    30361 tcctgctatc gttaccatcg ttctttctct tggtactcaa gttttggcca aacgacattc
    30421 catcgttcgt aagttgccag cagttgaaac acttggttca actgaaatca tcgcttctga
    30481 taagactggt acgctgacta tgaacaagat gacagtcgaa aaagtcttct acgatgcggt
    30541 tctacatgac tcagctgatg atattgaact aggtcttgaa atgccactac ttcgttcagt
    30601 tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac ttgattggtg acccaaccga
    30661 aacagccttt atccaatatg ccttggacaa gggctatgat gtcaaaggtt tcttagagaa
    30721 atatcctcgt gtagctgaat tgccatttga ctctgaccgt aagctcatgt caacagttca
    30781 cccattgcca gatggtcgtt tccttgtagc agtcaagggt gcgccagacc aactcttaaa
    30841 acgttgtctt cttcgtgata aggctgggga tattgctccg attgatgaga aggttacaaa
    30901 tctcattcat acaaacaatt ctgaaatggc tcatcaagcc ttgcgtgtcc ttgcaggtgc
    30961 ttataagatt atcgatagta ttccagaaaa tctcacttct gaagagcttg aaaatgattt
    31021 aatttttact ggtttgattg ggatgattga ccctgaacgt cctgaagccg ctgaggctgt
    31081 tcgtgtggct aaggaagcgg gaatccgtcc aattatgatt acaggtgacc accaagacac
    31141 agcggaagcc attgccaaac gtttgggaat cattgacgca aacgatacag aaggtcacgt
    31201 tttaactggt gctgaactca atgaactgtc agatgaagaa tttgaaaaag tcgttggtca
    31261 atactctgtt tatgcccgtg tgtctccaga acacaaggtt cgtatcgtca aggcttggca
    31321 aaaacaaggt aaagtcgttg ccatgacagg tgacggtgtc aatgacgcgc cagctctgaa
    31381 aacagccgat atcggtatcg gtatgggaat cactggtaca gaggtttcta agggggcttc
    31441 tgatatgatt cttgcagatg ataactttgc gactattatc gtcgcagtgg aagaaggacg
    31501 taaggtcttc tcaaacattc aaaagactat tcagtaccta ctttctgcta atactgctga
    31561 agtattaacc atcttcctat caaccttgtt tggttgggat gtcttacagc cggttcatct
    31621 tttgtggatc aacttggtaa cggatacctt cccagctatc gctcttggtg ttgaacctgc
    31681 ggaacctggt gtcatgaatc ataaaccacg tggacgcaag gcaagcttct tctcaggtgg
    31741 tgttttgagt tctatcattt atcaaggtgt actccaagca gctcttgtta tgagtgttta
    31801 tggccttgcg attgcttacc cagttcatgt gggtgacaat catgctattc atgcagatgc
    31861 cctaacgatg gcctttgcaa cccttggttt gattcagctc ttccatgcct acaatgtcaa
    31921 gtctgtctac caatccatct tgacagttgg cccattcaag tctaagacct ttaactggtc
    31981 catcttggta tcctttatcc ttctcatggc aacaatcgtt gtagaaccgc ttgaaggaat
    32041 cttccacgta accaaactag acttgtcaca atggggaatt gttatggctg gaagcttctc
    32101 aatgattatc atcgtcgaaa tcgttaagtt tactcaacgc aaactcggtt ttgacaagaa
    32161 tgcgatttaa gggaggtttc ggatgtcagc atatcaatta ccgaccgtat ggcaggatga
    32221 agctagtaat caaggagctt ttacggggct aaacagacca acagcaggtg cccgtttcga
    32281 acaaaacttg ccaaaaggag aacaagcttt tcagctttat tcactgggaa caccaaatgg
    32341 tgtgaaggtt actatcttat tggaagaatt actagaagct ggttttaagg aagcggctta
    32401 cgacttgtat aagattgcta tcatggatgg ggatcaattc ggctcagact ttgtgaagct
    32461 caatccaaat tccaagattc cagccttatt ggaccagtca ggtactgaaa acgtaagagt
    32521 ctttgagtct gctcatattc ttctttacct tgctgagaaa tttggagcct ttttaccaag
    32581 taatcctgtg gaaaaggtag aagttttgaa ttggctattc tggcaagtag gtgcagcacc
    32641 ttttctaggt gggggatttg gacatttctt caattatgct cctgaaaaat tggaatatcc
    32701 tattaaccgt tttacgatgg aagtgaaacg ccagttggat ttattggata aggaattggc
    32761 tcagaaacct tatattgcag gcaatgacta tacgattgca gatattgcta tctggtcttg
    32821 gtatggacag ttagttcaag gaaatcttta ccaaggttct gcaaaattct tggatgcctc
    32881 aagttatcaa aatctagtaa aatgggcaga aaaaattgcc aatcgtccag ctgttaagcg
    32941 tggcttggaa gtaacttata cagaaattaa atagcaaaaa agtcatcttc ggatggcttt
    33001 ttgctacagt tgagggaaag ggtttgcagt tatcggcttt tgtgctataa ttgctataat
    33061 atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa aattgtgaag gatatcttat
    33121 ttttatctca agtgtctcag ccggcaagtc aggaggacct ttatcttgcc agagatttgc
    33181 aggatacact cttagcaaat cgtgatacct gtgttggtct agctgccaat atgattggga
    33241 tgcagaagcg cgtgattatc tttaatcttg gcttggttcc cgtggtcatg tttaacccag
    33301 tgcttctgtc ctttgaagga tcctatgagg cagaagaagg ctgtttgtcc ttggtaggtg
    33361 tgagatcaac taagcgttat gaaaccataa ggcttgccta tcgtgacagc aagtggcagg
    33421 aacagaccat taccttgaca ggcttcccag ctcagatttg ccagcatgag ctggatcact
    33481 tggaaggacg aatcatttag gaggaaagca aatgaaacga atagtctttg aacttatttt
    33541 tatcgcaacg acctggtata tctttttacc gccccttaac ctgaccagct gggaatttct
    33601 cttcttcctc tgtgggcatt tgttagttgt ggcaatctta tttggctttg gcaaggggat
    33661 aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg gaagctgcct taaatcttga
    33721 gggtttcaaa atcaatcggt tagggaaaat tctgttagct tcgattggag gaattcttct
    33781 cttggcagct ttggtttcct tggtaacttc tagcatgttt caggctaaaa attatgccaa
    33841 tgtagtcacg gttacggaaa aagactttac tgaatttcct aagagtgaca ccagtaaggt
    33901 tcctatccta gatagaagta ctgctgaaaa aattggagac cgctacttgg gttccctaac
    33961 cgataaggtg tcgcaatacg tagcggcaga tacctatacc caattgacaa ttgatgggaa
    34021 accttatcgg gtcacaccac tagaatatgc agaccctatc aaatggttta acaatcaagc
    34081 caagggaatc ggtgagtata tcaaggtgga catggtaact ggaaatgcgg atttggtgga
    34141 cttgaagaca ccaatcaagt attcagactc ggagtatttt aaccgtgatg tcaaacgtca
    34201 cctgcgcttg aagtacccga ccaaaatctt taaaactcca tcttttgagg tggacgatga
    34261 gggcaatcct ttctatgtag caacggttta ccaaaagcaa tttggacttg cggttcctcg
    34321 tcctgcttca gtcattatct tggatgctac aaatggagaa accaaggaat acagcttatc
    34381 agacgttcca gaatgggtgg acaggatcta tccagcagag gaaaccattg agcaaatcaa
    34441 ctacaacggc aagtacaagg acggtttctt gaatgccatg atttccaaga aaaacgtgac
    34501 ccagactacc aatggctata attacttgtc tatcggtaat gacatctatc tctacacagg
    34561 tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc atccttgaaa atatgcgaac
    34621 aggagaaatc actaagtata gcttggcttc tgcgacagaa gaatcagccc gtgaatcagc
    34681 agaaggtgct gttcaggaga aatcctacaa agcaaccttc ccaattctca tcaacctcaa
    34741 tgacaagcct ctctacatca tgggcttaaa ggacaatgct ggcttgatca aagagtacgc
    34801 cctggtagac gcagtcgagt accaaaatgt tatcgttgct actacagtgg aagagatgct
    34861 cagcaagtat gccaataaaa acgaccttga aattgacaat gcaacgacag aaagcatcaa
    34921 gggagtagta gcagacctca aatcagctgt tatcaaggga gacactgtct acttctttaa
    34981 agttgatggc aagatataca aggtaaaggc ttcagtatcc gatgaccttc cttaccttga
    35041 aaatggtaaa accttcgaag gtcaagtagg aaaagacaat tatctcaaga cctttaaagt
    35101 acaataatac tcttcgaaaa tctctagctc tatctgcaac ctcaaaacag tgttttgagc
    35161 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtataaa aaaggtttat
    35221 ttaataaata tatgttataa taaggtaaat taagcctaat ggaggacaaa gaaatgggtt
    35281 tttatttgat ggttgcttca atgctactcg gactgctcgc tttgaagata ggtttttctc
    35341 agttcaagga gaaaaaagat aaattcttat ctatcttaac aagtttagct ggcatagccc
    35401 ttgttctcgc ggctgtctgg ttaggatggc ccaaataaat agaaaaacct cggtcaaacc
    35461 gaggtttttc aaatgaattt cttggttgtg gctaaaaaat atgctacact atcaatatga
    35521 aaattttaat cccaacagca aaagaaatga acacagactt gccaagtatc gaggcaattc
    35581 ctttaaaacc agaaagtcag accgtgcttg atgccttggc tctctattct gccagtcaat
    35641 tggagagttt ctacaaggta tcagctgaga aagcggcgga agaatttcaa aatatccaag
    35701 ctttgaaaag gcaaactgct caacactatc cagccttgaa actttttgat gggcttatgt
    35761 accgcaacat taagagagat aagctgaccg aggcggaaca agattatctt gaaaatcatg
    35821 tcttcattac ctcggctttg tacggtgttg ttccagcctt gtcacccatg gctcctcacc
    35881 gtttggattt tttgatgaaa ttaaaagtcg ctggtaagac tttgaagagc cattggaagg
    35941 cagtctatga tgaagctctg aagaaggaag aagtgatttt ctctctcttg tcatcagagt
    36001 ttgagactgt attttctaag gaaatcagag caaagatggt gaccttcaaa ttcatggagg
    36061 atagaggcgg tcagctgaag attcactcaa ctatctccaa gaaagcgcgc ggggcctttc
    36121 taacagcttt aatagaaaat caagtacaaa ctgtggggga agcacgtcgc ttgaactttg
    36181 ctggatttgt ttaccgagaa gatttgtcac aaccacaggg attggttttt gtaaaggaag
    36241 tatagaaatc agataagaga aaagtcagca cgattatgct gacttttttg ataacttata
    36301 aagtattgga caaatgaatc tcatttgata aggtgttaag atgattaacc aaattcatga
    36361 ttgacagatg atttcggcaa ataaacttct tggtaatccc tggaatatag aaattagaca
    36421 cgatgatatc gtaatctgtc tgatttaaaa tctcaggact tgtttttaat tcatcccaaa
    36481 tatcgaaggt aaagcggtta ttacagtaat aggaaagcat atcaacaaag gtaagggata
    36541 tagcatggtc aaagttactg ataatcaaaa ccttgatagg tggtcgattt tctaacaact
    36601 gagtagagag gttttcagca tgggttaaga tggtgtacat caagtgttcc aactgttcag
    36661 gatggtcatg ctgtccaatt gcctgacggt attgagccag ttcttgacgc gcacttccca
    36721 taaagtctgg gaagtaaact tcaaattttt taatcgtcaa tgctttttgt tcaaataaga
    36781 ttggggtaga aaagatttcc tgtctttcaa agaaagcagt gttgtgtaaa tgccaaatca
    36841 gctcatcgtg gttagtaaaa gtaatcttat attgttttga taggcgttct aatatttgac
    36901 taagtaattg gtaagagtat cttgcttgac tgttatcttc taaagagttg aagaattctt
    36961 gaggatctag gaaaatatca ttctgaagaa aagaaataaa aatttgagcg attgtatctg
    37021 gagtcatttc aagcccaaaa tgtttagaga aataagcaag tgtctcctgg aaatttggaa
    37081 tgctctttaa aagaggataa tattctttgt aaaagtggtt ggggaggtca atgaagtgac
    37141 catttttaac cctgtggata ctgatagcta tcatcagttt gtacattcta taaattgaaa
    37201 atcgcattgg ataattcgtg attttataga agaagtcagc aaactctgtt aaatcttcct
    37261 caggaaggtc aggaaaaggc caatctagga aataatagcg ctcagaaaag tattgggcaa
    37321 aaaagtaacg aatatcgatc tcatttccac gtatctcgga tggagtaaaa gataattcaa
    37381 tttgaaactg agatgaaaga acctttgtaa tatttctgcc cagtcgatag aggttggcac
    37441 tactaaagta aagattttct attgttcgat aaataggtag cccctcattg aagaacatat
    37501 actctagtaa ttgaaaagat tgagaattag caagaaaata ttgataaata tcttctacac
    37561 tagtgttaac ttctaaatct atcatgattc cgttaacaga agattggatg ttaatagatg
    37621 gaaaggcaat acgtaattca tttaaatcac tttttaagat tcgttctgtg catcctaatt
    37681 tttcggctag ttcatgtaat ttcatccaat tacgattctg aattagggtt tccattaagc
    37741 gtaattgtct ttgaactttt gtggataaaa ggtttctcat acgggtattt cctccataat
    37801 tcattatatc tttttttgtc taagtagtat aaaaaaatta gagcaagaaa attgtcgtta
    37861 gtaatcggaa aaattagaat aatataagtg gctttcaagt gcaaaaacag aatatattaa
    37921 ttgttcagaa aatattgatt aatgcctcaa atagttgtac attgtaaact ataaaatact
    37981 atctaggagt ttaaaatgaa acattcacat aaaaaatcat ttgactggta tagcatgcaa
    38041 caacgttatt ctattcgtaa gtattacttt ggtgcagtta gtgtcttgct cggtaccgct
    38101 ttggtattag gtgcagcagc tagtgtccaa acagtacaag cggaagaaaa caaacaagaa
    38161 actaccaata gtatttctgt tggtagggga gaagcagcta ctaaaccagc agaggtttct
    38221 gcgtctaata aagagaaaac ctatgcagct ccaactgtag ctaatccagt agaaacgact
    38281 ccagttaaaa ctggagaagt tactaaacca gcagaaaaag ttgaagaagc aaaaaacaaa
    38341 aaagaggaag taacgcatca agatgctatt gacaagtcaa aattgttaac ggctctttcg
    38401 cgtgctaaaa agttagaaag caagttatat acagaagcaa gtgctgctaa cttgcaaaca
    38461 agtatccaag ctggtcaaag cttgcttggg aaagcagatg catctgaagc tgaattatca
    38521 gcagcagagt catctattca atcatctatt attggtctag aacttcgttc taactctaac
    38581 aaaggaactg tatcagaaac tcctgtagcg aagaaagcta atatagttga agcgaaggaa
    38641 gagactaatc cagctgcaac aactgatcgt tcagctgttg atagtgctgt tttgccaact
    38701 agcacagctg ccaaagtaga aacaacttca gctccagcat ctattaatga aatcttgaaa
    38761 ccaggtttga gcctttctga tgctcgccaa aatccagcta tccgtaagga agatgttgat
    38821 agagggtata gtggttttag agcggcgcct gctccaacga accaaccagt aactaatcta
    38881 ggaaataata ctgttttcac tgatattagc agaggttctc atactttccg tggtaatgga
    38941 aattcacgtc gtggaaaccc gattcatttt gatgtaacaa caactagagt tagaaataga
    39001 gtagatttct caatcagata ttcaggacca ggtgagtttg ttaataacaa ctttatctta
    39061 gacaaaggaa atggattcgg agaaccttct cgtgcaactg tttcaacacc aaaattaaga
    39121 gaccaagtta aaaacattag taagggtgga aactttgttt ctcattcagg ctacagttta
    39181 gaagctgcag tagaaacaag caccaatcaa acaattaagt ttagtttacc tatagccaac
    39241 cctaatggtg atctgtctgt tcgattaaga cctgttactt ttaatgtagg tcaaggggaa
    39301 tcaggatctg caactagtaa tgatccatat agtaactcta actattactt cagagaaaaa
    39361 ccactcctct tggatgcaaa tccaaatggt ggtactaata ataagactgt ttcagaagac
    39421 attgacttcc aaactgtcta tcttccaact agtaagttac cagaaggtca aactagatta
    39481 gttcgagaag gtgaaaaagg acaacgtcaa attacctata aagttcatcg atttggtaac
    39541 gaaacagtct taggattgcc aattagtaat agagttacta aagaagctaa gccacgtatt
    39601 atgcaaattg gtgtggctaa agagctaatc gatacagtaa aaccacgtgt tgatcaaaat
    39661 aaagttggtg atacaaataa cctcactttc tatcttgata acgatggcaa cggtgtttat
    39721 actgaaggtg tagacgaact tgttcaaaaa attgctatta aagatggagc taaaggtgaa
    39781 aaaggagacc aaggtgaacg cggtctaact ggagctcaag gagctaaagg tgaaaaagga
    39841 gcccgaggcg aacgcggtct aactggagct caaggagcta aaggtgaaaa aggagaccga
    39901 ggtgaacgcg gtctaactgg agctcaagga gctaaaggtg aaaaaggaga ccgaggtgaa
    39961 cgcggtctaa ccggagctca aggagctaaa ggtgaaaaag gggaccaagg tgaacgcggt
    40021 ctaaccggag cacaaggtgc taaaggtgaa aaaggagccc aaggtgaacg cggcctaact
    40081 ggagctcaag gagctaaagg tgaaaaagga gcccaaggtc aggcaggtcg tgacggtgta
    40141 actccaaccg taaccgttaa agataataaa aatgacggca ctcatactat cactattaac
    40201 gacggtagag gtaatgttac aagtactgtt gtaagagatg gtttcgatgg cgcaagtcca
    40261 ttagttgcga ctcaacgaaa tgacgcagat aagacaacaa ctgttatctt ctattacgat
    40321 aaaaatggaa acaatgaatt agatgcttct gataagaaat taaaagaagt tgtaattgca
    40381 gatggtgcta aaggtgaaaa aggggacaaa ggtgaacaag gtcttcaagg gcgtgatggt
    40441 gaacaaggac caaaaggaga agatgggaaa accccaacag ttaaagtaac tgatggtcaa
    40501 gatggaacgc atacaattac aattaacgat ggtaaaggtg gtataactac tacagtagta
    40561 agagatggat ttgatggtgc aagccctctt gtttctactc atagaaatga agcagataaa
    40621 acaacaactg ttattttcta ttatgatcta aatgataata atcaatttga tgaaggagat
    40681 acaaaactta aagaagttgt tatcgcagat ggaaaacaag gaccaaaagg tgacaaaggt
    40741 gcagacggtg ccaagggtga aaagggagat cagggtgaac gcggtctaac tggatctaaa
    40801 ggtgaaaaag gagaccaagg tgaacgcggt ttaactggag cgcaaggtgc caaaggtgac
    40861 aaaggtgaac aaggtcttca aggtcgtgat ggagctcaag gaccaaaagg cgcagatgga
    40921 caaagaggac cagcgggacc acaaggacca aaaggagaac aaggtaatcc aggaactcca
    40981 ggtaaagatg gaaaatctct aattgctgtt aaaaatggaa ctgaaacaaa agtctatgta
    41041 gaggatccgg ctagaccagg acaaccactt aatccaaacc aaccattagc aactatcact
    41101 gatggaagaa acggtactaa tggacaatca ccaacaatta cagcgacacg aagtgtgcaa
    41161 aatggcaaaa atggtgtatt agtaacaatt acaccagtag gaggtcgtcc acaaacaaca
    41221 tttgtagagg atggacaaaa gggtgctgat gggaaaaccc caacagtaac aataactgag
    41281 gggcaaaacg gcacacatac attaacggtt cataatccag gaagtccaga tgtgacaact
    41341 acgatccgtg atggagctac aggacaagca ggtcgtgatg gtaaagatgt attaaacgga
    41401 aaagtaaatc cacaaccaaa ccaaggtaaa aatggagata aatatattaa taccgaaacc
    41461 ggtgatgtct atgttaaaaa caatggaaac tgggataaag aaggcaacat caaaggccct
    41521 aaaggtgaca aaggtgcaga tggtgctaaa ggcgaaaaag gagaccaagg cgaacgcggc
    41581 ctaactggag cgcaaggagc taaaggtgcg gatggcgcag taggtcgtga tggacgtgac
    41641 ggtaaagacg tgttgaacgg caaagctaac ccagaagcac atcaaggtaa agacggcgat
    41701 aaatacgtta atacagaaac aggcgacgtc ttcgttaaga ataacggcaa ctgggataaa
    41761 gagggcaaca tcaaaggccc taaaggtgac aaaggtgcag atggtgctaa aggcgaaaaa
    41821 ggagaccgag gcgaacgcgg cctgactgga gcgcaaggag ctaaaggtgc ggatggagca
    41881 gcaggtcgtg acggacgtga tggacgtgac ggtaaagacg tgttgaacgg caaagttaac
    41941 ccagaagcaa atcaaggtaa agacggcgat aaatacgtta atacagaaac aggcgacgtc
    42001 ttcgttaaga ataacggcaa ctgggataaa gagggcaaca tcaaaggccc taagggtgac
    42061 aaaggtgaac gcggagaaga tggtaagact ccagaagtaa ctgtaactcc aggtaaagat
    42121 ggccatagta ctgacattac attcactgtt ccaggtaaag atccagttac agtaaatgtt
    42181 aaggacggag aaaatggtct gaacggtaaa actccaaaag ttgatttact tcgtgtccaa
    42241 ggaaaaaacg gaaatccatc tcatacaatt gtgacattct atacagatga aaacaatgac
    42301 ggcaaatata caccaggaac tgatgaactt ctaggttcag aaatgattaa agatggtgct
    42361 aaaggcgcgg acggacgaga tggtaaatca ttgcttactg tcaaggatgg taaagaaact
    42421 aaagtttacc aagaagatcc agctaaccca ggacaaccat taaatccaga aaaaccactt
    42481 gcggtaatta gagatggagt agatggaaaa tcacctacag ttacagctgt tcgtaaagat
    42541 gaagcagggc ataaaggtgt agaaatcact gttgataacc atgatggttc acaaccaact
    42601 acagtctttg ttcaagatgg tgctaaggga gaaactggtg caatcggtca ggatggacaa
    42661 actcctacaa tcactactca acgtggacaa gatggccaaa gcactgttgt aactatcaca
    42721 acaccaggta aagatccagt aaccttcact gtaaaagatg gtaagaatgg taaagatggc
    42781 cgtgcaccga aaatcaaagt agaagatatt acttcacctt caagaattag acgcgctaca
    42841 gatgctgctg caactccaac gcgtaacggt atccgtgtta cagtttatga tgatgttaat
    42901 gacaatgggg tatacgacgg aggtgtcgat aaagtattaa atagtaaaga tatttataac
    42961 ggtatagatg gacgtgatgg ttcagctcca actattacta caaaagataa tggagatgga
    43021 acacacacta tcacagttca aaatcctgat ggttctgaat caacaactgt tgttaaagat
    43081 ggtaaagacg gtaaaactgc gaatatcact acaacagaaa acccagatgg aagccacaca
    43141 attacggtga caaatccaga tggttcaact aaagaaactg ttgttaaaaa cggtaaagac
    43201 ggtaagactc ctaaagttga agtaacggat aacaacgatg gaactcacac agttaaagtg
    43261 acggatggag acggtaatgt aacgaacgct atcatcaaag atggtaaagc tgcaacagca
    43321 acaactactg aaaatccaga tggaagccac acagtaacaa tcactaaccc agacggaact
    43381 aagaatgagt ttgttgttaa gaatggacgt gacggtgttg acggacgtac tccaaccgca
    43441 tctgttcgtg ataatggaga cggaagtcat acaatcgtta ttacaaatcc agaaggtgtg
    43501 acaactgaaa ccacagttcg tgacggtaaa tcaccaactg ctaaggttgt ggataacgga
    43561 gatggaacac acactatcac agttgtgaac tcagacggaa caactacaac aactacagtt
    43621 cgtgatggta gagaaccaaa acttgaagtt attgataaca acgatggttc acacactatt
    43681 aaagtgacag gtgctgatgg taaagaaacg acaactacaa tctttgatgg taaatcacca
    43741 aaagcgaaca tcgttgataa cggagatgga actcatacat taacaatcgt agattctgat
    43801 ggtcgtgaat acaaatctat tattaaagat ggtaaagacg gcaaagatgg cgtttcacca
    43861 actgtaactg ttgaaaataa taacgatgga actcacgttg ttacaatcac taatccagat
    43921 ggaagtaaga cagaaatggt gattaaagac ggtaaagatg gtaaatcacc aaaagtttct
    43981 gttgaagata atggtgatgg tagtcataca atcacaatca tcaattctga tggaactgtg
    44041 acaaaaacag ttattaaaga tggcaaagat ggtagagatg gacgtgatgg tagagacggc
    44101 aaagatggaa aatgtggatg ccaagacaaa ccagtaacac catcaaatga caaaccagtt
    44161 cctccaacac caaatgtgcc gacaccagaa gtaccggtta aacctgtgcc agcgcaacca
    44221 acaccaaatg taccgacacc agaagtgcca gtacaaccaa ctccagctgt tccaacacca
    44281 gaagtaccgg ttccagaaca accagtagta ccaacaccgg ctcaaccagc aactccagta
    44341 aatgctaatc cagtagcacc aactacaggt aaagaaaacc gtggggacaa attacctgaa
    44401 actggaagcc aatctgatta tatctctgtt cttttaggta gcggtattct attgagccta
    44461 tatgtaggac gaagaaaaga agattaatca gccaaaagca gtcactaatt tctcgaaaga
    44521 agatgataag tgatagatct cgaatgaaag aatattctta gaatgatttt cctatgatgg
    44581 aaaagactgc taaaaacctt gagtggtaac gctcaaggtt tttttggatg gctgatgttt
    44641 gtctgaaaat cttgattgag aaataaaaag ccaccctatt aggtggctat aattgattta
    44701 gactttctaa aattttctat tttttactga atcgcttcga ccaagtcttg agcttgtttt
    44761 tcaagtgagt ttaggactgt ttcttcaaga accaattttc cgtctgccca ggcagagtca
    44821 ttaacacgtg cagcagtgaa atcaccaacg ccttgtgtac ggataaatgg caagaggtct
    44881 ttgtagatag cgaaaagttg atcgtgccct gcattggcta cagatgatac tgtgacaaac
    44941 ttgtcttgaa gggcagaagc gccacgtgta tcagacaagt caagggcacg agatagccag
    45001 tcaagcaagt tttttactgt accagggata gagaagttgt agactggaga gaaaatccag
    45061 atagcatccg caacgagaac tgcttcacga gcagcagcta cagctggatg tgttggaact
    45121 tccaaatctt ggctgaagag aggaagggct gaataatcaa ggtagctaac ttccgcttta
    45181 ccagcaagtg ctttctcagc ttcgagcgcc atttggtggt tgaaagaacc ttgacgtagt
    45241 gatccgacga taaataatac ttttttagac atgatgtgtc tcctttttct taaaatttcg
    45301 agaactctct cgttgttata aaatatatta caacaaaaca aaagaacttg caagaaattt
    45361 gctcagagtt tatttgaaaa ttgtaaaatt tcggaaactc taatcatttg tgactgaaaa
    45421 agtaagaact gtttcacttt caaaatcggt tttgtttgaa gggagaaata gaattggttg
    45481 ctcaaagcac agctttgagg ttgcagataa agctgacgtg gtttgaagag attttcgaag
    45541 agtattctta tattcacttg taataaagct taatagatgg taaaatagac gagtgaaaaa
    45601 aagacaaaac aaagcaaaaa ataatctact gtggcagtat ggtctaggga tgacgatttt
    45661 gtttgtggtt atcagtgctt cctttctgta tatggtttct cttagcatga aaccctatca
    45721 aacagctaaa agtgaaggag aaaaattagc tcagcagtat gcaggattag agcaggccga
    45781 tcaggttgat ttatacaatg gcttggaatc ttattacagc gttcttggtc gtaataaaca
    45841 gcaagaagca cttgctgttc tgattggaaa agatgatcat aagatttacg tttatcagct
    45901 aaatcagggt gtttcacaag aaaaagcaga aacggtttct aaggaaaagg gagctggcga
    45961 aattgacaag attatctttg gtcgttatca agataagcca atctgggaag tcaagtcagg
    46021 atctgatttt tatctagtag attttgaaac aggagcattg gtcaacaagg agggcctatg
    46081 aaattatcca accgtgtttt agaaatggaa gaaagtgtga ctttggctgc tggagcccgt
    46141 gccaaagcac tgaaggctga gggtagagat attttgtctc taaccttggg tgagccagat
    46201 ttcactactc ccaaaaatat ccaagatgcc gccattgcat cgattcgaga tgggcgtgct
    46261 tctttttata cagtaacctc aggtctgcca gagcttaagg cggcggtcaa tagctacttt
    46321 gagcgctttt acggctattc tgtagcgtca aatcaagtga cagtcgctgc gggagccaaa
    46381 tattctctct ataccttctt tatggctgtg gtcaatccag gtgatgaagt catcatccca
    46441 accccatact gggttagcta tggagatcag gtcaagatgg cagaaggcgt tcccgtcttt
    46501 gtttctgcta aggaagacaa tcactttaag gtgaccgtag agcagttaga agcagctcgc
    46561 actgacaaga ccaaggtttt ggtgctgaat tcgccatcta atcccacagg tatgatttac
    46621 acccgtgagg aactcttggc aattggaaac tgggctgtag aaaatgatat tctcatccta
    46681 gcagatgata tctatggccg cttggtttat aatggtcatg agttcacacc gatttctagc
    46741 ctatcggaag cgattcgcaa gcaaacagtg gtcatcaatg gtgtgtctaa aacctatgcc
    46801 atgactggtt ggcggattgg ttatgccgtt ggagaagcag acattatcgc tgccatgtcc
    46861 aagattgcag gtcaaacaac ttcgaatccg tcagcagtag cccaatatgc agcagttgag
    46921 gctctatcag gtgagcaaga tactgtagaa agcatgcgtc aggcctttga agaacgtctt
    46981 aataccatct atcccctcct tgcagaagtg ccaggatttg aagtggtcaa accgcaaggg
    47041 gccttctatc tcttcccaaa tgtcaaaaag gccatggaga tgaaaggcta cacggatgtg
    47101 acagacttta caactgttat cttagaagaa gccgaagtgg ccttggtaac aggagctgga
    47161 tttggagcac cagaaaatgt ccgcctcagc tatgcgacag acctagacac gcttaaagaa
    47221 gcagtcgaac gcttgaaagc atttatgggt agtgagaatg attgatcatt ttgagattaa
    47281 ggtaaaggat ttacaaattt cagaaggatt ttataggagt tttctcgctc ctttggacta
    47341 taaattggct tttaagacta gttctctaat tagttttcta tccccgaaca gccctcatcc
    47401 tggtggtgat ttttggctga ctcagggaac acaagatcct gttcattttg cttttttagc
    47461 agaaaataag gaagaagttc aggcttgtta tgaggctggc ttagaggcag gtgggcgaga
    47521 caatggggct cctggttatc gaagtgagca tccgatttac tatgctgctt ttatgattga
    47581 cctggatggg aacaatatag aggtggtttg ccataaagaa taaaaaagaa aaggaaaaat
    47641 aatgacaaaa cgtgtaacga ttattgacgt aaaagactat gttggtcagg aagtgacgat
    47701 tggcgcttgg gttgccaaca aatcaggaaa agggaaaatc gctttcttac aattgcgtga
    47761 tggaacagcc ttctttcaag gtgtggcttt taaaccaaac tttgtcgaaa aatttggtga
    47821 agaagtggga cttgagaagt ttgatgttat caaacgcttg agccaagaaa cgtctgttta
    47881 tgtgacaggt attgtcaaag aggacgaacg ttctaaattt ggctatgagt tggacatcac
    47941 agacatcgaa gtgatcggtg aatctcaaga ctacccaatc acaccaaaag aacacggaac
    48001 agactttttg atggataacc gtcacttgtg gctacgctct cgtaagcaag tagctgtgtt
    48061 gcaaatccgt aacgctatta tctatgcaac ttatgagttc tttgacaaga acggttttat
    48121 gaagtttgac agcccaattc tttcaggaaa tgcggcagaa gattctacag aactctttga
    48181 aactgactac ttcggaacgc cagcctactt gagccaatca ggtcagcttt acctagaagc
    48241 aggggctatg gctcttggtc gtgtctttga ctttggtcca gttttccgtg ctgaaaaatc
    48301 aaaaacacgc cgtcacttga ctgagttctg gatgatggat gctgagtact catacttgac
    48361 acatgatgag tcgcttgact tgcaagaagc ttatgtgaaa gctcttctac aaggtgttct
    48421 tgaccgcgcg cctcaagcct tggaaacctt ggaacgtgat acagaactct tgaaacgcta
    48481 cattgcagag ccattcaaac gtatcactta cgatcaagcc attgacctct tgcaagagca
    48541 tgaaaatgat gaagatgctg actacgagca tcttgagcat ggtgatgact ttgggtcacc
    48601 acacgaaact tggatttcaa accactttgg tgtgccaaca tttgtcatga actatccagt
    48661 agccatcaag gccttctaca tgaaaccagt tcctggaaat ccagagcgcg tgctttgtgc
    48721 agacttgctt gctccagaag gctatggaga aattatcggt gggtctatgc gtgaggaaga
    48781 ttacgatgcc cttgtcgcta agatggatga acttggcatg gatcgtacag aatatgaatt
    48841 ctaccttgac cttcgtaaat acggtacagt tccacacgga ggatttggta tcggtatcga
    48901 acgtatggta accttcgcag caggaacaaa acatatccgt gaagctattc cattcccacg
    48961 tatgttgcac cgtatcaaac cataagaaca ggaaaacgcc catgtggcgt tttttcgaat
    49021 tctagtgttt ttacttgcgt aaaaaaattt tttctagtat aatagtttac tgtgagcgaa
    49081 cctcacttac cccttgcaaa gtcttggggt cattagacca aaaggaggaa catatcaatg
    49141 gctaaatacg aaattcttta tatcattcgt ccaaacattg aagaagaagc taaaaacgct
    49201 ttggtagcac gttttgactc tattttgact gacaacggtg caactgttgt tgaatcaaaa
    49261 acttgggaaa aacgtcgtct tgcatacgaa attcaagatt tccgtgaagg actttaccac
    49321 atcgttaacg ttgaagcaaa tgacgatgca gctcttaaag agtttgaccg tctttcaaaa
    49381 atcaacgctg acattcttcg tcacatgatc gtcaaaattg acgcgtaaga aggtaaacta
    49441 tgattaacaa tgttgtactt gtagggcgta tgacacgtga cgctgagttg cgttataccc
    49501 catcaaatgt agcagttgcg acttttactc ttgcagtaaa ccgtacattt aagagtcaaa
    49561 atggtgaacg tgaggctgat tttatcaatg tcgttatgtg gcgccaacag gctgaaaatc
    49621 ttgctaactg ggctaaaaaa ggctcactta tcggggtgac aggtcgtatc cagactcgta
    49681 gttacgataa ccagcaagga caacgtgtct acgtgacaga ggtcgtggct gagaatttcc
    49741 aaatgttgga aagccgtagt gtgcgtgagg gtcacacagg tggagcttac tctgcaccaa
    49801 ctgcaaacta ttcagcacct acaaattcag taccagactt ttcacgtaat gaaaatccat
    49861 ttggagcaac aaacccattg gatatttcag atgatgattt accattctaa tggacaacta
    49921 aacttataaa ggagaaaaaa catggctcaa caacgtcgtg gcggattcaa acgccgtaaa
    49981 aaagttgatt acatcgcagc aaataaaatt gaatatgttg attacaaaga tactgaactt
    50041 cttagccgtt tcgtttcaga acgtgggaaa atccttcctc gtcgtgtaac aggaacttca
    50101 gctaaaaacc aacgtaaagt aacaacagct atcaaacgtg ctcgcgtaat ggctttgatg
    50161 cctttcgtaa acgaagatta aagaaaagac ccggttgggt ctctttttca tgagcttgaa
    50221 aacaagaaag cgaattaaga ccccaacggg tcttttttca caagctttga aatgagagag
    50281 cgagttaggc tcagtggctc cctttttacg agtttgaaaa caagagaaca cattaaaagc
    50341 acgatggagc tttttcataa atatgtctct tttctcatcc aagaaattaa aataaaaatg
    50401 ataaactttt tgaaaatagg ggatttgcct actttatgat ataatggaaa gagttagatt
    50461 gaaagaggta gtgagatgga cgcgaaatta agatacaagg caaagaagat caagattgtc
    50521 ttttttgata ttgatgatac attgcggaat tcaaagacag ggtttattcc aactacaatt
    50581 cccactgttt ttaaacagtt gcgtgaaaaa ggaattttaa caggaatcgc ctctggacgt
    50641 ggcatttttg gtgttgttcc agagattcgt gatctcaagc ctgacttttt tgtaactttg
    50701 aatggggctt atatcgaaga taaaaaaggt caggtcattt atcagcatca gattgaaaag
    50761 tcagatgttg aggagtatat ctcttgggct aagcaagaag gaattgagta tggcttggtt
    50821 gggagtcatg atgccaagtt gtcgactcgc accgatatga tgagtgaagc tatcaatcca
    50881 atttatcccg acttagatgt agatcccgat ttccatgaaa aagaagatat ctatcagatg
    50941 tggacttttg aagataaggg agatgacttg cacttgcctg atagtctctc agacaaactt
    51001 cgcatggttc gttggcatca acattcgtct gatattgtgc cgatttcagg ctccaaagcg
    51061 acgggggtgg aaaaggttgt ggaacacctt ggcttgaaac cagagaaggt catggttttt
    51121 ggagatggtc tcaacgactt ggaactcttt gattatgctg gaatcagcgt tgctatggga
    51181 atttctcatg ataaaatcaa agaaaaagca gattatatta caaaaacatt agaagaagat
    51241 ggcatttttg atgccttaga agtatttggt atggtagaaa aagaattgca ttttccacaa
    51301 gtagacattg aaacagtaga aggtcctctt gcgactatta agaccaatca cggagactta
    51361 cgtatcaagc ttttccctga acatgctcct aaaacagtgg ctaactttgt atctctttca
    51421 aaagatggct actatgatgg tgtcattttc caccgtatta tcaaggactt tatgatccaa
    51481 ggtggagacc caactggaac tggtatgggt ggcgagtcaa tctacggcga atcttttgag
    51541 gatgaattct cagaagagct ttacaatatc cgtggtgctc tttccatggc aaatgctggt
    51601 ccaaatacca acggcagcca gttctttatc gtgcaaaacc aacacctacc ttattctaag
    51661 aaagaaatta ctcgtggtgg ttggccagaa ccgattgcag aaatctatgc caatcaaggt
    51721 gggacacctc acctagaccg ccgtcacacg gtttttggtc agttagctga tgaagcatct
    51781 tacgctgtct tggatgccat tgctgctgtt gagacaggag ctatggacaa gccagttgaa
    51841 gatgttgtaa ttgaaactat tgaaatcgag gactaagatg aaaatcggtg ataagctaaa
    51901 ggggcgtatt acagggattc agccctacgg tgcctttgtt gagttagaga cgggtgatac
    51961 ggggctgatt cacatttcag aaattcggac aggatttatt gaaaatattc atgaaacctt
    52021 gaaagtcgat gaagaggttc aagttcaggt agtggattta gatgaattta cggggaaagc
    52081 cagtctttct atccgcactt tggaggaaga aaagtaccag tttcctagac ggagacgctt
    52141 ttcaagcgac cgctttaact acggttttgc tccctttcga cgaatgctac caatctggac
    52201 tggagaagcc ctgcaccatt taaaaaagaa gaagtagttt agagttttat attttttgta
    52261 atgttaatat aaatttgcta taataggacc atggaagaag aacaattatt aaaatcagga
    52321 gagcgcatta accagctctt ttcgacagat atcaaaatca ttcaaaatag agaggttttt
    52381 agctattcgg tggatagtgt tctcttatca cgatttccac gttttcctaa gaaggggttg
    52441 attgtggatt tctgtgctgg gaatggagca gtggggcttt ttgctagcac tcgtactcaa
    52501 gcacagatat tgtctgttga gattcaggag cgtttggcgg atatggctga acgctctgtc
    52561 cgtttgaatg gattagagga gcaaatgcag gtcatctgcg atgatttgaa aaatatgcct
    52621 gctcacattc aggggagtaa ggtggatatg attttgtgta atccacccta tttcaaggtg
    52681 gatccttatt ctaatctgaa cgagagtgaa cattatctct tggctcgaca cgaaatcacg
    52741 actaatttgg aagaaatctg tcgtagtgcc cagagtattc tcaagtctaa tgggcgtttg
    52801 gccatggttc atcgtcctga tcgacttctg gatattttgg atacgttaaa acgacataat
    52861 ctagccccta agcgcctgca gtttgtttat ccaaaaagag aaaaggaagc caatatgctt
    52921 ttgattgagg cgatcaagga tggctcaaca agtggcttta aggtcttacc tcctttgatt
    52981 gtccacaatg atgatggctc ttatacgccc gaaatcgaag agatttatta tggatcataa
    53041 ggcttatatg tacgttctgg agtgtcgtga tggatcctac tatataggct atacgactga
    53101 tgtgagaaga cgcctcgcta tccacaatag tgggaaggga gccaaatata cacgagcacg
    53161 cttgccagtc aaacttatct atgctcaagg ttttgccagt aaggaagaag ccatgtcggc
    53221 tgaagctctt ctcaagcgta agaagaggcc acagaaggaa gaatttttat ctgaaaatca
    53281 agatagaaat ttactcagtt attttgaaga atcgtgggga gtcctttgac tcctcttacc
    53341 tttgtcaaaa agcgaaaaaa atgctacaat aaagaaaata aacaaaatga ggtattatca
    53401 tgtccaagat tctagtattt ggtcaccaaa atccagactc agatgccatc gggtcatctg
    53461 tagcttttgc ctaccttgca aaagaagctt acggtttgga tacggaagct gttgcccttg
    53521 gaactccaaa tgaagaaaca gcctttgtct tgaactattt tggtgtggaa gcaccacgtg
    53581 ttatcacttc tgccaaagca gagggggcag agcaagttat cttgactgac cacaatgaat
    53641 tccaacaatc tgtatcagat atcgctgaag tagaagttta tggtgttgta gaccaccacc
    53701 gtgtggctaa ctttgaaact gcaagcccac tttacatgcg tttggagcca gttggatcag
    53761 cgtcttcaat cgtttaccgt atgttcaaag aacatggtgt agctgtgcct aaagagattg
    53821 caggtttgat gctttcaggt ttgatttcag atacccttct tttgaaatca ccaacaacac
    53881 acccaacaga taaaatcatt gctcctgaat tggctgaatt ggctggtgtg aacttggaag
    53941 aatatggttt agcaatgttg aaagctggta ccaacttggc tagcaaatct gctgaagaat
    54001 tgattgacat cgatgctaag acttttgaac tcaacggaaa taatgtccgt gttgcccaag
    54061 tgaacacagt tgacatcgct gaagttttgg aacgccaagc agaaattgaa gctgcaatgc
    54121 aagctgccaa cgaatcaaac ggctactctg actttgtctt gatgattaca gatatcgtca
    54181 actcaaactc agaaatcttg gctcttggtg ccaatatgga caaggtcgaa gcggctttca
    54241 acttcaaact tgaaaacaat catgccttcc ttgctggtgc cgtttcacgt aagaaacaag
    54301 tggtacctca attaactgaa agctttaatg cgtaagattt tgggtgtcag ctcaaaatcg
    54361 gaaagtctag tttgccttat atcgaaagga gtttcggctc ctttttttct aggagtgaag
    54421 tatgttagaa aatggcgatt tgatttttgt gagagatggg tcagacatgg gacaggccat
    54481 ccagacttcc acaggtaact atagccatgt tgccatttat ttggatggga tgatttatca
    54541 tgctagtgga caggctggtg ttgtctgtca agaaccggca gacttctttg agtccaatca
    54601 tttgtacgac ctctatgttt atccagaaat ggatatccag tcggtgaagg aaagagcttg
    54661 cagacatctt ggagcaccct acaatgcttc tttctatcca gatgcagctg gtttctactg
    54721 ctcccagtat atagcagaaa tcctacctat ttttgaaact attcctatga aatttggaga
    54781 tggagaacag gagattagtg atttttggag ggagtattac atagaactag gtctgcctgt
    54841 tcctctgaac caagctggga ccaatcctag tcagttggca gcatcgcctc tgttacaatg
    54901 taaagaaagg aatcttcatg attcagattt ttaatccatc tcgtttgacg agacagccat
    54961 ttttggagaa ttgaaccgct atctggacca gtatgaggat gtgattctac gggaaattaa
    55021 ggctcaattt ccagatattg cagttgataa acttatggaa gagtatataa aggcaggctt
    55081 gattctacgt gaaaataagc gctattacct caattttcct acgcttgaat cacttgatag
    55141 tcttgaactg gatcaagaga tttttgtcag agaagctagt ccggtctatc aagccttgtt
    55201 ggagcagagt tttgagacgg aattgcgcaa tcaaatcaat gcagctattt tagttgaaaa
    55261 gacggacttt gcgcgcatta aaatgaccct gtccaattat ttttacaagg tcaaacagca
    55321 gtatcctttg acagaaaaac agcaggagct ctatgacatt ttaggagatg ttaatcctga
    55381 gtatgtcctc aagtatatga cggctttttt gttgaaattt ctcaaaaaag accagcttat
    55441 gcagaaatgc cgtgatatct ttgtggacag tttggttgtc ttaggctata ttgtgcaaaa
    55501 tgaagatgga aagtatgagt tggctatcga ttttgataag gagagattaa ctttctactt
    55561 agcgtgattt cttgtttctg agcacattgt ttgactttcc ttagtattcg gtataaacta
    55621 tatgtaaccg gtaacacata tcggaataaa ctaaaggata caatcatatg tcacttgaaa
    55681 acaaattgga acaagcaaca ggcgctgtca aagaaggttt tggtaaagtt actggagaca
    55741 gcaagacaga acttgaagga gctgttgaaa aaacagttgc taaggcaaaa gacgttgtag
    55801 aaaacgcaaa aggtgctgta gaaggtgccg ttgaaggttt gaaaaacgtt tttactaaag
    55861 aataggaaaa aatcaagggt ttcattttcc cttgattttt tctattctta taaataattt
    55921 tctgcgacgg ctgtatctcc tgggtaggat tctttcttgc cctggatgat ttggtaacaa
    55981 tcggctccct tacccgcaat aataactgca tctaattcgt gatttgtgat agccattgcc
    56041 gccttgatgg cttcttggcg atccgcaatc ttttcaacag gatgattgat gtagctacta
    56101 atttcatctg caatggccat tgggtcttca tagttagggt catcagcagt cagaaagact
    56161 tgaatctcag ggtgttgatt gaggaggagg ccaaagtcct tacgacgact ttctcccttg
    56221 tttcctgttg atcccagaac cagagcaatc tttccggttt gatgagtttc aaccacattg
    56281 atgagttttt tcagactatc cccattgtgg gcatagtcga tgaagacctt ggctccattt
    56341 ttctgagtga ggacttccat acgaccagga acgcgggttg cagcgatgcc ttttttgatg
    56401 tcctcaagac ttgctccgag acggagacaa gcaagtccag cagcaactgc attttcttgg
    56461 ttgaagttgc caatgagttg gatatcataa tctccagcga gtttacccgt agctgaaaag
    56521 ctaaaggctt tggaattctc gatttggtta tcaaattggc taccatagaa atcatggttt
    56581 tgatcttcaa cctgttcttt caagactgag aagtggtcca tgtcactgtt aatgatgact
    56641 gctcggctat tttccatcaa gagacgcttg tggtagaaat agtcttcaaa gctagggtgt
    56701 tcaatcgggc cgatatggtc ttggctgata tttaggaaaa ctcccacatc aaaggttaga
    56761 ccatagacac gtttgaccag ataggcttga ctggagactt ccatgatgag gtgggtacgg
    56821 tcattttgca cagcctgatt catcatgtca aagaggtcaa tactctcagg ggttgtcaac
    56881 gctgacttaa agaaagtctc gccatcaaga gttgtgttca tggtcgacaa catagcaggt
    56941 cgatgccctt gagataagat gttataggcg aaataggctg ccgttgtctt acccttagtt
    57001 cctgtgaagg cgagaatttt gagtttctct tgtggattac catagaactc catggcaatc
    57061 aaactcatgg ctttctttat atcgttcaca atgatgacag ggataccgac ttcgtagtcc
    57121 ttttcagcta cataccaagc taaaccttgt gttatagcag aaagaaggta ttctttttta
    57181 aaggcagcgc cttttgcaaa aaaaagagtg tcttctgtta cttttcggct gtcgtagctg
    57241 atgctatcaa aaacaacttt gctgtagttg tagtggtaat gaccttggtc aataatttcg
    57301 cgaaaaaggc catctttctt taaaatatct aatacggttt caatcttaat catactttct
    57361 attgtaaacc gaaagtcgca aatttacaag taacaaggaa aagtttataa tggaagataa
    57421 ggagtttttc ctagttatca aaattgaatg aggaatctat gtcgcacgaa aacaatcacc
    57481 agcaggccca gatgttacgg gggactgctt ggctaacggc tagtaacttt atcagtcgcc
    57541 tactcggggc tgtttacatt atcccttggt acatctggat gggggcttat gcagctaagg
    57601 caaatggtct ctttaccatg ggttacaata tctatgcttg gttcttgttg gtttcaacag
    57661 cggggattcc agttgcggtg gccaagcaag tttccaagta taataccatg cgagaagaag
    57721 agcatagctt tgccctgatt cggagcttct taggctttat gacaggacta ggcctggttt
    57781 ttgctttagt cttgtatgtc tttgctcctt ggctagcaga cttgtctggc gtgggcaaag
    57841 acttgatccc aatcatgcaa agcttggctt ggggagtctt gattttcccg tctatgagtg
    57901 ttatccgagg atttttccaa gggatgaata acctcaaacc ctatgccatg agccaaattg
    57961 ctgagcaggt cattcgtgtt atctggatgc tcctagcaac ctttatcatt atgaagctcg
    58021 gttcaggaga ttatctagca gccgttaccc aatcaacctt tgctgccttt gtcggtatgg
    58081 tagccagttt tgcagtcttg atttatttcc ttgcccaaga aggttcactc aaaagagtct
    58141 ttgaaacagg agataagatt aacagtaagc gtctcttggt tgataccatt aaggaagcca
    58201 ttccttttat cctgacaggg tctgccatcc agctcttcca gattttggat cagctgacct
    58261 ttatcaatag tatgagctgg tttaccaact acagcaatga ggacttggtt gtcatgtttt
    58321 cttatttctc agccaatcct aataaaatca cgatgatttt gatttctgta ggggtttcga
    58381 ttgggagtgt tggtttgcca cttttgacgg aaaactatgt caagggggac ttgaaagcag
    58441 cttctcgtct cgttcaggac agtctcaccc tactctttat gttcttgcta ccagcaacgg
    58501 ttggagtggt tatggtagga gagcctcttt atacggtctt ctatggtaag ccagatagtt
    58561 tggctatgag cttatttgtc tttgcagttt tgcagtctat tattttaggc ttgtacatgg
    58621 tcttgtctcc aatgcttcag gccatgttcc gcaaccgcaa ggccgttctc tattttatct
    58681 atggttctat tgccaagcta gtcttgcaac tacctaccat cgccctcttc cacagttatg
    58741 gtcctttgat ttcaacaacc attgctctca tcattcctaa cgtcttgatg tatcgggata
    58801 tttgtaaagt aactggtgtc aagcgcaagg tgattttgaa gcgaaccatt ttaatcagtt
    58861 tgctgaccct agtcatgttt ctgttaatag gaaccatcca gtggctgtta ggatttttct
    58921 tccaaccaag tggacgtttg tggagcttct tttatgtagc tcttgtcggt gccatggggg
    58981 gtggacttta tatggttatg agtctgcgta cctatttgtt agataaggta ataggaaaag
    59041 cccaagcaga tcgcctgcga gcaaaattta agctttcgta aggtagcatt tataaataaa
    59101 aggaataagt tgaacaatct tttaggagaa cttgaaactt attccttttt tagcgtcaaa
    59161 atagctaaaa ttatctttca aaaatagcaa atgaggtttt tttcgatttt ttggaaaaat
    59221 aattgactaa acaaaccaaa cgttgtataa taaaacaaat atttaaagca ggaggttctg
    59281 gaaatgaaaa agtctaagag caaatatcta accttggcag gtcttgtcct gggtacagga
    59341 gttttattga gcgcgtgtgg aaattctagc actgcatcaa aaacctataa ctatgtttat
    59401 tcaagtgatc catctagttt gaactatcta gcagaaaacc gcgcagcaac atccgatatt
    59461 gttgcaaatt tggtagacgg gttattagaa aatgaccaat atgggaatat tattccatca
    59521 ttagcagagg attggactgt ttctcaggac ggtttgacct atacctacaa acttcgtaag
    59581 gatgccaagt ggtttacttc tgagggagaa gaatatgcgc ctgtaactgc ccaggatttt
    59641 gtgacaggtt tgcaatatgc agctgataaa aaatcagaag ctttgtatct agtgcaggac
    59701 tctgttgctg gtttggatga ctatatcact ggtaaaacaa gcgacttttc aactgtcggt
    59761 gtcaaggcac ttgatgacca aacggttcaa tatactttgg ttaaaccaga actttactgg
    59821 aattcaaaaa cacttgcaac gatacttttt cctgttaatg cagatttcct gaaatcaaaa
    59881 ggggatgatt ttgggaaggc ggatccatct agtattttgt acaatggacc tttcttgatg
    59941 aaagcacttg tctcaaaatc tgctattgaa tataagaaaa accctaatta ctgggatgct
    60001 aagaatgtct ttgtagacga tgtgaaattg acctactatg atggtagcga ccaagaatca
    60061 ctggaacgta attttacagc tggtgcttat actacggctc gtctttttcc taacagctcc
    60121 agctatgaag ggattaaaga aaaatacaaa aacaatatca tctatagtat gcaaaattca
    60181 acttcatatt tctttaattt taacctagat aggaagtctt acaattatac ttctaaaaca
    60241 agtgacattg aaaagaaatc gactcaggaa gcagttctca ataaaaactt ccgtcaggct
    60301 atcaattttg cttttgacag aacatcttat ggggctcagt ctgaagggaa agaaggtgca
    60361 acaaagattt tgcgtaacct agtggttcct ccaaactttg tcagtatcaa gggaaaagac
    60421 tttggtgaag ttgtagcctc taagatggtc aactatggta aggaatggca aggtatcaac
    60481 tttgcggatg gtcaagaccc ttactacaat cctgagaaag ccaaggctaa gtttgcggaa
    60541 gctaagaaag aactcgaagc aaagggtgtt caattcccaa tccacttgga taagactgtg
    60601 gaagtaacag ataaagtagg catacaagga gttagttcta tcaaacaatc aattgaatct
    60661 gttttaggtt ctgataatgt agtgattgac attcagcaat taacatcaga tgagtttgac
    60721 agttcaggct actttgctca aacagctgct cagaaagatt atgatttata tcatggcggt
    60781 tggggacctg attatcaaga cccgtcaacc tatctcgata tttttaatac taatagtgga
    60841 ggatttctgc aaaatcttgg actagagcct ggtgaggcca atgacaaggc taaggcagtt
    60901 ggactggatg tctatactca aatgttggaa gaagctaata aagagcaaga tccagccaaa
    60961 cgttatgaga aatatgctga tattcaagct tggttgattg atagttcttt agttcttcca
    61021 agtgtttcgc gtgggggaac accatcattg agaagaaccg taccatttgc tgctgcctat
    61081 ggtttaaccg gtacaaaagg ggttgaatca tataaatacc tcaaagtaca agataagatt
    61141 gtcacaacag acgaatatgc aaaagccaga gaaaaatggt tgaaagaaaa agaagaatcc
    61201 aataaaaaag cccaagaaga attggcaaaa catgtcaaat aaaatctaat tgtagataag
    61261 tttgtgtaag aagtctttgt gcttaaaaac gcataatatc aggtatataa aatcctagat
    61321 gttatgcgtt ttgttatagg aagatttatt agattttatc ctcaaattga gttattcccg
    61381 actttatccg ttgaaatatt ataaggagta tttatgaaat taaaattatt aagagtagat
    61441 actaaggtga ttatggggag tttcttactt gttctgtcta gtctacttgc tttgttgctt
    61501 ccccttatct taaagggttt aatagatggg agttctattg aaaatatagg ttccaaagta
    61561 tttcaatcgt ttttgatttt tattggtcaa gccttgtttt cttctattgg ttactatctg
    61621 tttagtcaat cgggtgaaaa aaagatagca aaaatcagga aaaaagtgat agaggggttg
    61681 atttatgcag agaaatcctt ctttgataag agccaaagtg gggagttgac ttctgccatt
    61741 gtcaatgaca cgagtgtcat tcgtgagttt ttaattacga ctttcccaaa tattattctg
    61801 agtttagtta tggtacttgg ttccattgta gtcttattta gtcttgattg gaatctttct
    61861 ctacttttat tcatcactct tccttgtatg atgtttatta tcttgcccct ttccaatatc
    61921 agtgaaaagt atagtcgtcg tttacaggag gaaatttaac agggcaattg actgaaaaga
    61981 ttcaagaaca tgaattaatt aagactaacc aagcagagaa aagtgtacag gatgttttgg
    62041 ataattgtat tgaaagggta caaaacaatt cactgaaatc agatagggtt acttcttttg
    62101 agacctcgtt tgctctctta tttatctttg cgactatagt tgtgatgcta acctatgggg
    62161 gttatcgggt cagcgcagga tatatatctg tgggaacctt ggtttcgttt ttgatttacc
    62221 tctttcaatt acttaatcct attagtaata tagctaattt tgtaactatt tattctagta
    62281 gcaagggatc ttcagttgca ctggagaact tgcttgcagt tcctaaagaa aaatttgagg
    62341 gaggaaaatc ggtatcagga caagggttga attttaacca tgtctatttt ggttatgatg
    62401 aaaatcgacc tgtcttaaag gatattactt gttcaatttt caaggggcaa aaaattgctt
    62461 ttgttggacc atctggatca ggaaaatcaa cgattgtgcg tttgttagag cggttttata
    62521 aaccgctttc aggatatatt ctaatggagc aatcaagtat atatgatttt aacttaaaag
    62581 aatggagaag taaaatcgct tgggtttcac aaaataatgc agtcttatct ggcagtattc
    62641 gtgacaatct ttgtctcggt ttgaatcgct tagtaactga tgatgaattg atgaaagtgc
    62701 tagacttagt atcactaggt gatgagattc gctccatgaa agagggacta gatactgaag
    62761 ttggtgaacg cggacgactc ttgtcagggg ggcgaagcca aagacttcaa atagctagag
    62821 cctacttaaa agatgctgaa attcttatat ttgatgaagc cactgctaat cttgatgcgg
    62881 attctgagta tgcgattatc agtagcctct attctgtact aaaggagaag acggttgtga
    62941 ttatagcgca tcgtttgtca acggtaaaag atgtggattg tattttcttc ttagaggagg
    63001 ggaaaatcac tggctcagga actcataagg aactactgga aaatcatgag cgttatgctc
    63061 gttttgtgca ggagcaaatg atagagtgaa ggtgtctttt gagattcacc attttatagt
    63121 ctattaaagg gagcaggaaa aactcccttt ttatatagtt tgaaactata actagctctt
    63181 gaaaagaaga aaatgagttg atgaaaataa gtggtacaat agttactata gatttggagg
    63241 aattgtatga gcaaggaatt acacattaac acaattttag cacaagcagg gatcaagtct
    63301 gatgaggcaa caggtgcttt ggtgacacca cttcattttt caacgaccta tcagcatcca
    63361 gagtttggtc gatctactgg gtttgactat acgcgcacta aaaatccaac tcgtagtaag
    63421 gctgaggaag tcttggcggc tattgagtca gcagactatg ccctagcgac tagctcaggg
    63481 atgtcagcta ttgtactggc ctttagcgtc tttccagtag gaagtaaggt cttggcagtg
    63541 cgtgatcttt acggtggttc ttttcgctgg tttaaccaag tggagcagga aggtcgtttc
    63601 cattttacct atgccaatac agaagaagag ttgattgccg agttagaaaa ggatgtggat
    63661 gttctctata tcgaaacccc aaccaatccc ttgatgttgg aatttgatat cgaaaaacta
    63721 gcaaaattgg ctcatgctaa gggtgccaaa gtggtggtgg acaatacctt ctatagccct
    63781 atctaccaac gtccgattga agatggagca gatatcgttc tccattcagc aaccaagtat
    63841 ctagcaggcc ataatgatgt cttggctgga gtggttgtga ccaatagttt agaactatac
    63901 gagaagcttt tttacaatct caatacaaca ggggcagtct tgtctccatt tgacagctac
    63961 cagttgcttc gtggtctcaa gaccttgtct cttcgtatgg agcgctcaac agctaacgcc
    64021 caagaagtgg ttgccttttt gaaggattct ccagcagtta aggaagttct ctacactggt
    64081 cgtggaggca tgatttcctt taaagtagcc gatgaaacac gcattcctca tattttgaac
    64141 agtctcaagg tcttctcttt tgcggaaagt ttgggcggag tggaaagtct tattacttat
    64201 ccaacgactc aaactcatgc tgatattcca gcagaagtac gccattctta tggtttgaca
    64261 gatgacctct tgcgtttgtc tattgggatt gaggatacta gagatttgat tgcagatttg
    64321 cgccaagcct tagaaggata agacaaagat gggaaaatat gattttacaa gcctgcccaa
    64381 ccgtttaggg caccatacct ataaatggaa agaaacagaa acggatagtg aagttctacc
    64441 agcttggata gcggatatgg actttgtggt cttgcctgaa atccgccaag ccgtgcaaac
    64501 ttacgcagac caactggttt atggttatac ctatgccagt gaagacttaa ttaaggaagt
    64561 tcaaaagtgg gaagctacac aatacggtta caactttgac aaagaggctc ttgtctttat
    64621 cgagggtgtg gtaccagcca tctcaacagc tattcaaacc tttacaaaag aaggcgaggc
    64681 ggttttaatt aacacgcctg tctacccacc ctttgctcgc agtgtcaagt tgaataatcg
    64741 tagattgatt actaattcct tagtggaaaa ggatagtctg tttgagattg actttgacca
    64801 acttgaaaag gatttggtgg aagaggaggt taaactctat gttctttgca accctcacaa
    64861 tcctggtgga cgtgtttggg aaaaagaagt gttggagaag attggccaac tctgccaaaa
    64921 acacggtgtt ttgttagttt cggatgagat tcaccaagat ttgaccctct ttggtcacaa
    64981 acaccagtct ttcaatacca tcaatcctgc cttcaaaaat tttgctatcg tcttgagcag
    65041 tgccactaaa acatttaata ttgctggaac aaaaaattcc tatgcagtca ttgaaaatcc
    65101 taagttgaga ctggctttcc agaaacgcct gttggccaat aatcagcatg aaatttcagg
    65161 cttgggttat ttggcgacag aagctgccta tcgatacggt aaagattggc tagaggaact
    65221 caagcaagtc tttgaagacc acatcaatta tgtgatggat ctatttggaa aagagactaa
    65281 aatcaaggtc atgaaaccgc aaggtaccta cttgatttgg cttgactttt cagcttatga
    65341 cctgactgat gaaacattgc aagagttgtt gagaaatgaa gccaaggtta tcctcaaccg
    65401 tggtttggat tttggagagg aaggaagtct ccatgcccgc atcaatatag ctatgcccaa
    65461 atctctgttg caagaagtct gtcagcggat tgtggctact tttgccaaac gttaaaaatc
    65521 cagccttcta ggagaaaagt cttcctagaa ggctattttc ataggcgaaa atatggtata
    65581 ataaaaagat aaggtaaagg tgaaaatatg gctaaattga ttccggggaa aattcgtatc
    65641 gaaggtgttg ccctttatga aactggtaag gttgatatca tcaaggaaaa gaacaatcgg
    65701 ctctacgctc gcgttgcaga agaagaactg cgctatagtt tagaggatga tttggttttt
    65761 tgtgcctgtg attcttttca aaagaggggc tactgtgtgc atttggcagc gctagagcat
    65821 tttctgaaaa atgatgagcg tggtcaggaa atcttgtgga gtctggaaga aggtcatgaa
    65881 gaaaaagagg ccgttgaaac caaggtgacc ttgggtggca agtttttgaa tcgaatttta
    65941 tctccaaaat cagaatgcgc ctatgagtta tcagctgtgg gtcaggtgga agcaggaacc
    66001 aatcatatct tgtggactct gagaatcggc caaatcaata gccaaaaata ctatgtcatt
    66061 cgggatattc tacttttttt aaggattgtc gagcagagaa agtcgtatat gattggcaag
    66121 atttatgagg agtctctttc ttgggaagcc tttgatgatg ccagccaaga acttttgact
    66181 ttcttgcacg gactaacgga ggaagggctg gttccagacc tctttttcca aaaccaaggt
    66241 cggcacctct ttttccctct gacctttttt gagcagggtg tgaatttact gatggccttg
    66301 ccccattttc aatttgacca tcaagtggat agctaccaaa ccctgctttt tcaggatatg
    66361 catgctgatg ccaatctatt tgcctttaca gtaacagaat actcggacta ttttgaaatg
    66421 gaaatcagtg agagtcctag ggtcaatgtc ttttatcaag gagcagtact tttccataaa
    66481 ggtcaggttt attttttaac agaccagcag atgcgtcttc tcaaggaaat taaagcgtta
    66541 cctgtgggtc aacaaggaaa gaaatacctg caatttgata gcagtgatcg agacaaattg
    66601 gcctcctgtc tgactctttt tatccagatg ggcaccgttt cagctccaga acgtctacaa
    66661 attaaaactt ttgcgccctc tttttacttt gacagggaag aagataatcg gattcgttta
    66721 gaaattcagt ttgattatgg aaatagacag gtatctagcc gacaagagct agaagaatta
    66781 ccattttcaa gtgacgcgga cttagaagaa agaattttcc aagtctgttt ggctgcgggc
    66841 tttgaatccg attttcaatc ttggcgtcag gccttaaaag cggagtctgt ctatcatttt
    66901 tttcatgata tcattccagt ctttgaaaaa ctcgggcatg ttgacctatc agataaacta
    66961 gaagagcttt atagcctagc gagtcctcag gtgcagattg cttccaaggg aggtctcttg
    67021 gaaatccagt ttgattttca agatattgcc caggaggaaa tcgaccaagc catgcaggcc
    67081 ttggttgcca atcaggattt ttatattgat tcgtctaatc aagtttactt tttcgatgaa
    67141 gaaaccaaga aaattcgcca aaatctacag gaactggggc aatttgaatt aaaagatggg
    67201 accttgcagg ctcggaaatc cttggcctac agtttagctc atctctttga agggcgagac
    67261 cgtgtttctt tttcacaaga attccagaat ctggcccagg atttgacgca tccagaggac
    67321 tttcctttgc aagcaactca ggtcaaggct gacttgcgag attatcagga aaagggaatt
    67381 ggctggttgc agatgctcca tcattatggt tttggtggga ttttggctga tgatatggga
    67441 cttgggaaaa cccttcagac cattgctttt ttgactagtc aagtgacaaa agaaagtcgg
    67501 gttttgattc tcgctccgtc gggtttgatt tacaactggg cagatgagtt tcagaaattt
    67561 gctccacagt tggatgtggc tgttgttcat ggtttgaaag caagtcgtga ggagattctt
    67621 gccgagagcc atcaaatcta tgtgactagc tatgccacct tccgtcagga cagtgagctt
    67681 tatcagggga tggcctttga cttccttttc ttagatgaag ctcaggtcat gaaaaatgcc
    67741 cagaccaaga ttgcccagac cttgagacaa tttgtggtgc cgtcggtctt tgccttgtca
    67801 ggaactccga ttgaaaacca tctgggtgag ttgtggtcta ttttccaaat cgtcatgccc
    67861 ggacttttgc caagcaagaa agaatttatg aaattgccag cagagcgagt ggctcagttt
    67921 atcaagcctt tcgtgatgcg acgcaagaaa gaagaagttc tgactgaatt gccagacttg
    67981 attgaggtgg tttataaaaa tgaactggaa gaccagcaaa aggctattta ccttgcccag
    68041 ttacaacaga tgcgagacca tctggctcaa gtgtcagaac aggaatttca gcgaagtcgt
    68101 gtggaaattt tatctggttt gatgcgcttg cgtcaaatat gtgacactcc tgccctgttt
    68161 atggaagatt atcagggagc cagcggcaaa ctagatagtc tccgagacct actggtacag
    68221 gtggcagacg gcggacaccg tgtcttgatt ttctctcagt tcaagggaat gttggaaaaa
    68281 attgaacaag aactgccaga cttgggcctg acttccttta aaattacggg ttcaacccca
    68341 gccaaggaaa gacaagacat gaccaaggcc tttaatcaag gagaaagaga tgcctttctg
    68401 atttccctca aggctggtgg ggtcggtctg aacctgacag gtgcagatac agtgatcttg
    68461 gttgaccttt ggtggaatcc tgcggtggaa gcgcaagcca ttggccgtgc ccatcggatg
    68521 ggtcaggaag aaacggttga ggtctatcgc ttggtgacca agggaaccat tgaagaaaaa
    68581 attcaggaac tccaagaaca aaagaaacat ctggtgtcac aagtattgga cggcacagag
    68641 tcacgtggta gtctgaccct agcagaaatt agagaaattt tgggaatttc tgaagccagc
    68701 acttgaaaaa tcaagacaat acgctataat gaagtgttga aaggaaatag aaaatgaaac
    68761 aagaacgatt tccattggtg tcagatgacg aggtcatgtt gactgaaatg ccagtcatga
    68821 atctctatga tgagtctgat ctgatcagta atatcaaggg tgagtatcga gataaaaatt
    68881 atttagaatg ggctcctatt gctgaagaaa aaccagtaaa accgattgaa aagcaagtag
    68941 ggaaacctaa aaaagctcct ttaggggtta aaaaagaagg aaagagctat gcggaggtgg
    69001 cgcgtgaaga agcgcgtgca gacttgaaaa agaaacgctc tgctaactat ctaactcagg
    69061 atttcagcct tgcgagacgt cattctcagc ccagtctagt tagacagggc aatcaaccga
    69121 caactccttt ccaaaaggaa aatcctggtg aatttgtcaa atatagccaa aaattgaccc
    69181 agtctcatta tatcttggcg gaagaagttc attctatccc taccaagaat gaagaagtgt
    69241 cagcacctgc tccaaagaaa aacaattatg attttctaaa gaagagccaa atctacaata
    69301 aaaaaagtaa acaaacagaa caagaacgtc gggttgccca agagttgaat ctgaccagaa
    69361 tgacagaata ggggagaaaa catgtcaaag acatatcatt ttatcggaat taagggatca
    69421 gggatgagtg ccttggcctt gatgttgcac cagatggggc acaaggttca gggatcagat
    69481 gttgaaaagt actactttac ccaacgcggt cttgagcagg caggaattac cattcttcct
    69541 tttgatgaaa agaatctaga cggtgatatg gaaattatcg ctggaaatgc ctttcgtcca
    69601 gataacaacg tcgaaattgc ctatgcggac caaaatggta tcagctacaa acgttaccat
    69661 gagtttctag gtagctttat gcgtgacttt gttagcatgg gagtagcagg agcacatgga
    69721 aaaacttcaa cgacaggtat gttgtctcat gtcttgtctc acattacaga taccagcttc
    69781 ttgattggag atgggacagg tcgtggttcg gccaatgcca aatattttgt ctttgaatct
    69841 gacgaatatg agcgtcactt catgccttac cacccagaat actctattat caccaacatt
    69901 gactttgacc atccagatta tttcacaagt ctcgaggatg ttttcaatgc ctttaacgac
    69961 tatgccaaac aaatcaccaa gggtcttttt gtctatggtg aagatgctga attgcgtaag
    70021 attacgtctg atgcaccaat ttattattat ggttttgaag ctgaaggcaa tgactttgta
    70081 gctagtgatc ttcttcgttc aacaactggt tcaaccttca ccgttcattt ccgtggacaa
    70141 aacttggggc aattccacat tccaaccttt ggtcgtcaca atatcatgaa tgcgacagcc
    70201 gttattggtc ttctttacac agcaggattt gatttgaact tggtgcgtga gcacttgaaa
    70261 acattttccg gtgttaaacg tcgtttcact gagaaaattg tcaatgatac agtgattatc
    70321 gatgactttg cccatcatcc aacagaaatt attgcgacct tggatgcggc tcgtcagaaa
    70381 tacccaagca aggaaattgt agcagtcttt caaccgcata cctttacaag aaccattgcc
    70441 ttgttggacg actttgccca tgctttaaac caagcagatg ctatttatct agcgcaaatt
    70501 tatggctcgg ctcgtgaagt agatcatggt gacgttaagg tagaagacct agccaacaaa
    70561 atcaacaaaa aacaccaagt gattactgtt gaaaatgttt ctccactcct agaccatgac
    70621 aatgctgttt acgtctttat gggagcagga gacatccaaa cctatgaata ctcatttgag
    70681 cgtctcttgt ctaacttgac aagcaatgtt caataggatg ttcccatgga aattccaatt
    70741 aagatcattc aggcaagcaa gtctgatttg cctgagatag gggcacttca gacctcgtct
    70801 tttccagctg aaaagcagca actttcccat attttagaag aaagtatccg taagtgtgcg
    70861 gatacctttc ttctagctag ggatgaaaat caacttttag gctatatttt atcaagtccc
    70921 cagtcagaca atccgcaatg tctaaaagta cattctttag tcatcgagtc tgaccatcag
    70981 agacagggcc tgggaacact tcttcttgca gccttgaaag aggtggcagt tgagctggat
    71041 tacaaaggga ttcgtttgga gagtcctgat gagctgcttt cctattttga aatgaacggt
    71101 tttgttgatg aagaagcaac tttactctat gcaactagcc agggctatag tatgatttgg
    71161 tttaatccct tttatctgga ggaacaatga aaatcagaca agcaagatta gaagatttgg
    71221 atcggattgt tgaacttgaa tttgaaaatt tttcggtcga agaagccatt cctccttctg
    71281 tctttgaagc acatttgaga gaaattcaga cctcttttct ggttgctgaa aaagaaggaa
    71341 gaatcatggg ttatatcgaa ggaccagttg gcctgcaccg ccatctgcaa gaccagtctt
    71401 ttacagaaga aataaaagac tatagtcatg agcctggtgg ttatatctct gtgacctgtc
    71461 tgtctattgc caaggaggca cagggactcg gactgggtca gaaattgctg acagccttga
    71521 aagaagttgc tcttgaagat gagagagatg gcattaatct aacctgtcat gactatctca
    71581 tcgcctatta tgaaaaacat ggatttgtca acgaaggcca gtcccagtca acctttgcag
    71641 gggaaacatg gtatgatatg gtctgggaaa tgaaaaaata agttaggaaa agtatcatag
    71701 attgcttttt ttggactttt aagatataat attatggatt atcaacaagg aggaaaaact
    71761 tttgagtgaa aagtcaagag aagaagagaa attaagcttt aaagagcaga ttctgagaga
    71821 tttagaaaaa gtaaaaggct atgatgaagt tctgaaagaa gatgaggcag tagttcgcac
    71881 tcctgcaaat gaaccttcag ctgaagaact catggctgat tccttgtcaa cggtagagga
    71941 gattatgaga aaagctccta ccgtgcctac tcacccaagt caaggtgtac cagcttctcc
    72001 agcagatgag attcaaagag aaactcctgg tgttccaagt catccaagtc aagatgtacc
    72061 ttcttctcca gcggaagaaa gtggatcaag accaggtcca ggtcctgtta gacctaagaa
    72121 acttgaaaga gaatacaatg aaaccccaac aagggtagct gtttcctata cgacggcaga
    72181 gaaaaaagca gaacaagcag gtccagaaac acctacgcct gctatagaaa cagtggatat
    72241 catcagagat acatcacgtc gtagccgtag agaaggagca aaacccgtta agcctaagaa
    72301 agagaagaag tcacatgtga aagcttttgt gatttcattc cttgtattcc ttgccttgct
    72361 ctcagcaggt ggttactttg gttaccagta cgtgctagat tccttattac ctatcgatgc
    72421 taattctaag aaatatgtga cggttggaat tccagaaggt tcaaacgttc aagaaatcgg
    72481 tacgacgctt gaaaaagctg gtttggtaaa gcatggtctg atttttagtt tttatgccaa
    72541 gtataaaaat tataccgact tgaaagcagg ttactacaat ttgcaaaaga gtatgagtac
    72601 agaagactta ctcaaagagt tgcaaaaagg tggaacagat gaaccgcaag aacctgtact
    72661 tgcgactttg acaattccag aaggttatac cttggatcag attgctcaaa ctgtgggtca
    72721 attgcaaggt gacttcaaag agtctttgac agcggaggct ttcttggcta aagttcaaga
    72781 tgagacgttt atcagtcaag cagtagcgaa atatcctact ttactggaaa gtttgcctgt
    72841 aaaagacagc ggtgcgcgtt atcgtttgga aggatacctt ttcccagcta catactctat
    72901 caaggaaagc acaactattg agagcttgat tgatgagatg ttagctgcta tggataagaa
    72961 cctatctcct tactatagta ctatcaaatc taaaaacttg actgtcaatg agttgttgac
    73021 cattgcttcc ttggtcgaaa aagaaggtgc caagacagaa gatcgtaagc tcattgcagg
    73081 tgtattctac aatcgtttga atcgtgatat gccacttcaa agtaatattg caatcttgta
    73141 tgcccaagga aaactggggc aaaatatcag tctagctgag gatgttgcga ttgataccaa
    73201 cattgattca ccttataatg tttataaaaa tgtaggtctc atgcctggtc cagtcgatag
    73261 tccaagtctg gatgcgattg agtcaagcat caatcaaact aagagcgata acctatactt
    73321 tgtagcagat gtcacagaag gcaaggtcta ctatgctaac aatcaagaag accacgaccg
    73381 caatgtcgct gaacatgtca acagcaaatt aaactaaaca aactaaaatt atgtgatact
    73441 tcacataatt ttctttagaa aatattatca gaagaaagtt gagaaaaatg gcagaaaaaa
    73501 catatcctat gacccttgag gaaaaggaga aacttgaaaa agaattagaa gaattgaaat
    73561 tggttcgtcg accagaagtg gtagaacgca ttaagattgc ccgttcatac ggtgatcttt
    73621 cagaaaacag tgagtacgaa gcagctaagg atgaacaagc ctttgtcgaa ggacaaatct
    73681 ctagcttaga aacaaaaatc cgctatgctg aaatcgtcaa tagcgacgca gttgcccagg
    73741 acgaagtagc gattggtaaa acagtcacca tccaagaaat tggtgaggac gaagaagaag
    73801 tttatattat cgtaggttca gctggtgcgg atgcctttgc aggtaaggtt tcaaatgaaa
    73861 gcccaattgg gcaggccttg attggcaaga aaacaggtga cacagcaacc attgaaacgc
    73921 ctgttggtag ctatgatgta aaaatcttga aggttgaaaa aacagcctaa aaacagaaaa
    73981 aggagtgggg aggcgatgtg cttcactcac tcctttttcc attttgctat tcttcgaaaa
    74041 tctcttcaaa ccacgtcagc gtcgccttgc cgtatgtatg gttactgact ttgtcagttt
    74101 cat
//
LOCUS       DAVHSL010000004        68515 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000004 DAVHSL010000000
VERSION     DAVHSL010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.004"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            308..1171
                     /locus_tag="VVR39_000215"
     CDS             308..1171
                     /locus_tag="VVR39_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6029771.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEGV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            1457..1690
                     /locus_tag="VVR39_000216"
     CDS             1457..1690
                     /locus_tag="VVR39_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029772.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            1712..2389
                     /locus_tag="VVR39_000217"
     CDS             1712..2389
                     /locus_tag="VVR39_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6029773.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            2401..3066
                     /locus_tag="VVR39_000218"
     CDS             2401..3066
                     /locus_tag="VVR39_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6029774.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3138..4364
                     /locus_tag="VVR39_000219"
     CDS             3138..4364
                     /locus_tag="VVR39_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6029775.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4761..4838)
                     /locus_tag="VVR39_000220"
                     /pseudo
     CDS             complement(4761..4838)
                     /locus_tag="VVR39_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4909..5565
                     /locus_tag="VVR39_000221"
     CDS             4909..5565
                     /locus_tag="VVR39_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU6029776.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFAMLLGCSMGVVLDGQ
                     "
     gene            5555..5764
                     /locus_tag="VVR39_000222"
     CDS             5555..5764
                     /locus_tag="VVR39_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU6029777.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSSVVTGKVGNLPPIK"
     gene            5982..6812
                     /locus_tag="VVR39_000223"
     CDS             5982..6812
                     /locus_tag="VVR39_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6029778.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            6966..7820
                     /locus_tag="VVR39_000224"
     CDS             6966..7820
                     /locus_tag="VVR39_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6029779.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            7920..9293
                     /locus_tag="VVR39_000225"
     CDS             7920..9293
                     /locus_tag="VVR39_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU6029780.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9286..10347
                     /locus_tag="VVR39_000226"
     CDS             9286..10347
                     /locus_tag="VVR39_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU6029781.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAILQAGVQLKVLKGVQ"
     gene            10349..11041
                     /locus_tag="VVR39_000227"
     CDS             10349..11041
                     /locus_tag="VVR39_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6029782.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKTTSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11071..11640)
                     /locus_tag="VVR39_000228"
     CDS             complement(11071..11640)
                     /locus_tag="VVR39_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6029783.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11775..12389
                     /locus_tag="VVR39_000229"
     CDS             11775..12389
                     /locus_tag="VVR39_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6029784.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12391..14037
                     /locus_tag="VVR39_000230"
     CDS             12391..14037
                     /locus_tag="VVR39_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6029785.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14049..15335
                     /locus_tag="VVR39_000231"
     CDS             14049..15335
                     /locus_tag="VVR39_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6029786.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVASVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15396..15929
                     /locus_tag="VVR39_000232"
     CDS             15396..15929
                     /locus_tag="VVR39_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6029787.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            16007..16477
                     /gene="nrdI"
                     /locus_tag="VVR39_000233"
     CDS             16007..16477
                     /gene="nrdI"
                     /locus_tag="VVR39_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU6029788.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16770..18032)
                     /locus_tag="VVR39_000234"
     CDS             complement(16770..18032)
                     /locus_tag="VVR39_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU6029789.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18342..18800)
                     /locus_tag="VVR39_000235"
     CDS             complement(18342..18800)
                     /locus_tag="VVR39_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU6029790.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNCLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18797..19237)
                     /locus_tag="VVR39_000236"
     CDS             complement(18797..19237)
                     /locus_tag="VVR39_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6029791.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETTSQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19593..21542
                     /gene="mutL"
                     /locus_tag="VVR39_000237"
     CDS             19593..21542
                     /gene="mutL"
                     /locus_tag="VVR39_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU6029792.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGYGISHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIAIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21867..22334)
                     /locus_tag="VVR39_000238"
     CDS             complement(21867..22334)
                     /locus_tag="VVR39_000238"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU6029793.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(22335..23540)
                     /locus_tag="VVR39_000239"
     CDS             complement(22335..23540)
                     /locus_tag="VVR39_000239"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU6029794.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23560..24195)
                     /gene="ribE"
                     /locus_tag="VVR39_000240"
     CDS             complement(23560..24195)
                     /gene="ribE"
                     /locus_tag="VVR39_000240"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU6029795.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(24180..25280)
                     /gene="ribD"
                     /locus_tag="VVR39_000241"
     CDS             complement(24180..25280)
                     /gene="ribD"
                     /locus_tag="VVR39_000241"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU6029796.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(25413..25527)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25684..26277
                     /gene="ruvA"
                     /locus_tag="VVR39_000242"
     CDS             25684..26277
                     /gene="ruvA"
                     /locus_tag="VVR39_000242"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU6029797.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            26287..26850
                     /locus_tag="VVR39_000243"
     CDS             26287..26850
                     /locus_tag="VVR39_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU6029798.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAILENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWRGLK"
     gene            26847..27524
                     /locus_tag="VVR39_000244"
     CDS             26847..27524
                     /locus_tag="VVR39_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6029799.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27679..28710)
                     /locus_tag="VVR39_000245"
     CDS             complement(27679..28710)
                     /locus_tag="VVR39_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU6029800.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(28965..29648)
                     /locus_tag="VVR39_000246"
     CDS             complement(28965..29648)
                     /locus_tag="VVR39_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU6029801.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29660..30604)
                     /locus_tag="VVR39_000247"
     CDS             complement(29660..30604)
                     /locus_tag="VVR39_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6029802.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30736..33567
                     /gene="uvrA"
                     /locus_tag="VVR39_000248"
     CDS             30736..33567
                     /gene="uvrA"
                     /locus_tag="VVR39_000248"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU6029803.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            33560..34621
                     /locus_tag="VVR39_000249"
     CDS             33560..34621
                     /locus_tag="VVR39_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6029804.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34753..35151
                     /gene="spx"
                     /locus_tag="VVR39_000250"
     CDS             34753..35151
                     /gene="spx"
                     /locus_tag="VVR39_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU6029805.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            35217..35786
                     /locus_tag="VVR39_000251"
     CDS             35217..35786
                     /locus_tag="VVR39_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6029806.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35873..36139
                     /locus_tag="VVR39_000252"
     CDS             35873..36139
                     /locus_tag="VVR39_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU6029807.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            36143..36562
                     /gene="ruvX"
                     /locus_tag="VVR39_000253"
     CDS             36143..36562
                     /gene="ruvX"
                     /locus_tag="VVR39_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU6029808.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            36578..36883
                     /locus_tag="VVR39_000254"
     CDS             36578..36883
                     /locus_tag="VVR39_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU6029809.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            37091..38341
                     /locus_tag="VVR39_000255"
     CDS             37091..38341
                     /locus_tag="VVR39_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6029810.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            38338..38883
                     /locus_tag="VVR39_000256"
     CDS             38338..38883
                     /locus_tag="VVR39_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU6029811.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTLDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            39029..40561
                     /gene="cls"
                     /locus_tag="VVR39_000257"
     CDS             39029..40561
                     /gene="cls"
                     /locus_tag="VVR39_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU6029812.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            40639..40782
                     /locus_tag="VVR39_000258"
     CDS             40639..40782
                     /locus_tag="VVR39_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029813.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            40819..42357
                     /locus_tag="VVR39_000259"
     CDS             40819..42357
                     /locus_tag="VVR39_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6029814.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            42477..44684
                     /gene="nrdD"
                     /locus_tag="VVR39_000260"
     CDS             42477..44684
                     /gene="nrdD"
                     /locus_tag="VVR39_000260"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU6029815.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44696..44836
                     /locus_tag="VVR39_000261"
     CDS             44696..44836
                     /locus_tag="VVR39_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029816.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            44880..45386
                     /locus_tag="VVR39_000262"
     CDS             44880..45386
                     /locus_tag="VVR39_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029817.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            45379..45969
                     /gene="nrdG"
                     /locus_tag="VVR39_000263"
     CDS             45379..45969
                     /gene="nrdG"
                     /locus_tag="VVR39_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU6029818.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            45966..46583
                     /locus_tag="VVR39_000264"
     CDS             45966..46583
                     /locus_tag="VVR39_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU6029819.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            46859..47167
                     /gene="rpsJ"
                     /locus_tag="VVR39_000265"
     CDS             46859..47167
                     /gene="rpsJ"
                     /locus_tag="VVR39_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU6029820.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            47384..48010
                     /gene="rplC"
                     /locus_tag="VVR39_000266"
     CDS             47384..48010
                     /gene="rplC"
                     /locus_tag="VVR39_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU6029821.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            48035..48658
                     /gene="rplD"
                     /locus_tag="VVR39_000267"
     CDS             48035..48658
                     /gene="rplD"
                     /locus_tag="VVR39_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU6029822.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48658..48954
                     /locus_tag="VVR39_000268"
     CDS             48658..48954
                     /locus_tag="VVR39_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU6029823.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            48972..49805
                     /gene="rplB"
                     /locus_tag="VVR39_000269"
     CDS             48972..49805
                     /gene="rplB"
                     /locus_tag="VVR39_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU6029824.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            49909..50190
                     /gene="rpsS"
                     /locus_tag="VVR39_000270"
     CDS             49909..50190
                     /gene="rpsS"
                     /locus_tag="VVR39_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU6029825.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            50202..50546
                     /gene="rplV"
                     /locus_tag="VVR39_000271"
     CDS             50202..50546
                     /gene="rplV"
                     /locus_tag="VVR39_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU6029826.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            50559..51212
                     /gene="rpsC"
                     /locus_tag="VVR39_000272"
     CDS             50559..51212
                     /gene="rpsC"
                     /locus_tag="VVR39_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU6029827.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            51216..51629
                     /gene="rplP"
                     /locus_tag="VVR39_000273"
     CDS             51216..51629
                     /gene="rplP"
                     /locus_tag="VVR39_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU6029828.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            51639..51845
                     /locus_tag="VVR39_000274"
     CDS             51639..51845
                     /locus_tag="VVR39_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU6029829.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            51870..52130
                     /gene="rpsQ"
                     /locus_tag="VVR39_000275"
     CDS             51870..52130
                     /gene="rpsQ"
                     /locus_tag="VVR39_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU6029830.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            52156..52524
                     /gene="rplN"
                     /locus_tag="VVR39_000276"
     CDS             52156..52524
                     /gene="rplN"
                     /locus_tag="VVR39_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU6029831.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            52602..52907
                     /gene="rplX"
                     /locus_tag="VVR39_000277"
     CDS             52602..52907
                     /gene="rplX"
                     /locus_tag="VVR39_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU6029832.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            52931..53473
                     /gene="rplE"
                     /locus_tag="VVR39_000278"
     CDS             52931..53473
                     /gene="rplE"
                     /locus_tag="VVR39_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU6029833.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            53491..53760
                     /gene="rpsN"
                     /locus_tag="VVR39_000279"
     CDS             53491..53760
                     /gene="rpsN"
                     /locus_tag="VVR39_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU6029834.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            54045..54443
                     /gene="rpsH"
                     /locus_tag="VVR39_000280"
     CDS             54045..54443
                     /gene="rpsH"
                     /locus_tag="VVR39_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU6029835.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            54635..55171
                     /gene="rplF"
                     /locus_tag="VVR39_000281"
     CDS             54635..55171
                     /gene="rplF"
                     /locus_tag="VVR39_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU6029836.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYIGEFVRRKEGKTGK"
     gene            55255..55611
                     /gene="rplR"
                     /locus_tag="VVR39_000282"
     CDS             55255..55611
                     /gene="rplR"
                     /locus_tag="VVR39_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU6029837.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            55629..56123
                     /gene="rpsE"
                     /locus_tag="VVR39_000283"
     CDS             55629..56123
                     /gene="rpsE"
                     /locus_tag="VVR39_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU6029838.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            56095..56319
                     /gene="rpmD"
                     /locus_tag="VVR39_000284"
     CDS             56095..56319
                     /gene="rpmD"
                     /locus_tag="VVR39_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU6029839.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            56464..56904
                     /gene="rplO"
                     /locus_tag="VVR39_000285"
     CDS             56464..56904
                     /gene="rplO"
                     /locus_tag="VVR39_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU6029840.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            56917..58227
                     /gene="secY"
                     /locus_tag="VVR39_000286"
     CDS             56917..58227
                     /gene="secY"
                     /locus_tag="VVR39_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU6029841.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            58378..59016
                     /locus_tag="VVR39_000287"
     CDS             58378..59016
                     /locus_tag="VVR39_000287"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU6029842.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            59133..59351
                     /gene="infA"
                     /locus_tag="VVR39_000288"
     CDS             59133..59351
                     /gene="infA"
                     /locus_tag="VVR39_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU6029843.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            59376..59492
                     /gene="rpmJ"
                     /locus_tag="VVR39_000289"
     CDS             59376..59492
                     /gene="rpmJ"
                     /locus_tag="VVR39_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU6029844.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            59510..59875
                     /gene="rpsM"
                     /locus_tag="VVR39_000290"
     CDS             59510..59875
                     /gene="rpsM"
                     /locus_tag="VVR39_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU6029845.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            59893..60276
                     /gene="rpsK"
                     /locus_tag="VVR39_000291"
     CDS             59893..60276
                     /gene="rpsK"
                     /locus_tag="VVR39_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU6029846.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            60319..61254
                     /locus_tag="VVR39_000292"
     CDS             60319..61254
                     /locus_tag="VVR39_000292"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU6029847.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            61266..61652
                     /gene="rplQ"
                     /locus_tag="VVR39_000293"
     CDS             61266..61652
                     /gene="rplQ"
                     /locus_tag="VVR39_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU6029848.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            61917..62183
                     /locus_tag="VVR39_000294"
     CDS             61917..62183
                     /locus_tag="VVR39_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU6029849.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            62193..63530
                     /locus_tag="VVR39_000295"
     CDS             62193..63530
                     /locus_tag="VVR39_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU6029850.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            63774..64466
                     /locus_tag="VVR39_000296"
     CDS             63774..64466
                     /locus_tag="VVR39_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6029851.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGTG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(64569..66204)
                     /locus_tag="VVR39_000297"
                     /pseudo
     CDS             complement(64569..66204)
                     /locus_tag="VVR39_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(66194..67285)
                     /locus_tag="VVR39_000298"
                     /pseudo
     CDS             complement(66194..67285)
                     /locus_tag="VVR39_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(67298..68419)
                     /locus_tag="VVR39_000299"
                     /pseudo
     CDS             complement(67298..68419)
                     /locus_tag="VVR39_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        20374 a        12867 c        15033 g        20241 t
ORIGIN      
        1 aagtaggttc tttgtaaccg ctccattata aaatcctttc actcttccgg tatactatta
       61 ggaaaaacat aactggagga tattttgagc tcacacctca tcgttccagt ggctgttccc
      121 caagctcgtg tactgcccaa aaaagttaga cattctattt agaacgagga ttgagttctg
      181 tattgtacaa ggctcggtcc ttttagagtc agcttaaggc tggctttttc aatcaccaaa
      241 gtgtcagaat gttttgacaa atgaacacaa ataatgatat aatatgcaaa agctaggagg
      301 tggtaggatg attgaaaaaa tggaactggg ggaattttac aaggaattgc gcttggcgag
      361 aaagctcaag cagtcagatg tggcttgtgc tggactaaca gcctctcagt tgtccaagtt
      421 tgaactagga cagtctatgc tgtctgcaga caagctgatc ctagccatcc aagggatcaa
      481 tatgaatttt gatgagtttg ggcacaaact caacaactat caagaatctc cacatatgcg
      541 aattggtaga agggttgtgg attgcttttc ccatcaggat atagctgctt tagagcagct
      601 attggaggga gtcgatcaag aacagatggc gcagacctat cgtcgtttga atgccattgt
      661 gattaaaaat gcactccatt ccttagataa aagctacccg ctaacagagg aggatagcga
      721 gtttttgact acctacctct acgctattga gtcttggacc tggtttgaac tctatctttt
      781 ttgcaatact atgcccttct tgagcaatca agatctgatc tttttatcaa cctccttact
      841 cgaaaaatcc aaggaattta aagagttagt acacaatcga tggtatatga aaagtggtta
      901 tcttaatatc atctcagaac ttatggagcg caagctattt tcttatattc caatctttga
      961 agctgagctg gagcgcatgc tccgtccata cgatgttttt gaaaaagtat tgtggcagtt
     1021 tttaaagaag atgagcattt tccttcaaac caaaggaagc aatcaaaaag agattgaaca
     1081 ctttatccaa tctctgcaag tattagaaaa tccacaattg acagcccttt ttgaattgcg
     1141 tttgcagcaa tacaaagagc ttatcgatta gttagaaatg ggaaaaagat aataatatca
     1201 gcaacgatcg tcaataatgt taaaacttgt ttcttcatat tacttccctc ctcattagta
     1261 ataactttat tataccaggg aaataatcaa atctaccaaa atcgcaaatc tgaaatttct
     1321 ataagaaaaa atatcaaata tgcgattttc taaaataagc caatttccgt gttatactgt
     1381 ccttgtaaaa catttgaagc aaatcctagg tcgcagaagt ggtttacaaa tgaagataat
     1441 tgaaggagtg taaaagatgt taaatttaca atttgcagaa acaatggaat tgacagaagc
     1501 tgagttgcaa gatgttagag gaggcaacct cgtaaattct atgggaggtg gtggaagaag
     1561 tggtatatct ggttggggcg tcccaggaat ttaccctggt tggggcaatc aagggatgag
     1621 tcctaatcgt ggagcttttg attggactat agatttagca gatggattgt ttggccgccg
     1681 tagaagatag gctcttatag gagataatag gatgaagaaa atgaaagaag tgaaatttca
     1741 cctagcaact ggcttgttga ttttgactta ttacctcatt tttaatgtca catcagactt
     1801 agattttatg gttgctttgt ctgataatat gtactatgtg ttccaagttt tattggtact
     1861 tattctggga actatagcta caattgcttt tgtcaaaagt gaacattgga aagagtgtgg
     1921 tcgtttccag tttcgttggt cttacctggg tgttttcctt ctttcttttt tcttattgtt
     1981 cgtgtgggca aatctaacaa cctatatctt tcctcgtacc cagaatggaa gtacagtcgt
     2041 agaagtagcc accagtttaa caggaattag ctattttgtt acgcgaatac tttatactag
     2101 tattatcgca cctgtatcag aagaggttgt ttgtcgtggt cttttgatga caagtttatc
     2161 taaagttaag agatactatc ttgatgttct tgtttccgct gccatatttg gcgctatgca
     2221 tgttttgcag tatggttgga taacgacaga tttcataaag tattttggaa tgggcttgat
     2281 attttgtatg atgtttcgct acacccgatc catctattgg gctatagctc tgcatgcttc
     2341 atggaatagc ttcttactca ttgttacttt attggtattt ggatattaga aaggtgatat
     2401 atgaaaaaga taatctcaca ccgctacttt attatagttt ttctactagt tattgctgac
     2461 cagaagttca gtgttttagt tttacgcagc gaccttgttg ctgggctatc tgactttgcc
     2521 tattatctgt cggatatgat gttgaatttt cttgtggttt tatttgctct tattgctatg
     2581 atttggtcgg ggaaatggca gaaaatcaat agtagaaagt ttaaaggatc ctatcttttc
     2641 tattccttcc tagctctgct tgcttttgtt gcttggaatt ttgtcacctt ttttcttttc
     2701 ccacctactc gaaatgaaat ttcttatcaa catgctgctc ctacttttac aggagctacg
     2761 gcatttttga tgtatttttt ttatcctgtg attgcaggtc ccatttttga agacatgatt
     2821 tatcgtggat tagtgatgac tgctctggaa aaaggaaaga aatgggggct agatgtactt
     2881 ggttccgctg ttttatttgg ggtctcgcac attagtaatc acggttgggt cttgacagac
     2941 tttgtcttct atatgggtgg aggtcttata tttgcagtct tatttagaat gacaaagtca
     3001 atttattggc ctattggact gcatatagtc tacaatggta ttggtcagct tttgatgtta
     3061 ctgtaatttt ggttgttagt agtatcgcgg tctattcttg gggaaagatt cccatttgaa
     3121 tttaaaaagg agttgtaatg aaagtatttc ttcaaaatag agattttagg caattaacta
     3181 tcaaccagtg gatttcaacg cttggggata cgatttttta tctggccttc ctgaattatg
     3241 tggcagatgc gtcttttgcc cctttggcga ttttactcat tacgatttca gaaacccttc
     3301 cccaaatttt acaaatcttt ctgggagttt tggcagattt tcaacatcat cgtgtcttga
     3361 aatacacagt cattagtttt gcaaaatttt tgctttactc tatcgtttct ttatcacttt
     3421 cagggcagtc tttctccttg ttgctagtag catttatttg tctgattaac ctcttgtctg
     3481 acacattgag ttacttttca ggagccatgc tcactccgat tttcattaga attattgggc
     3541 aagaccatct ggcagaagct attggattta aacagtcaac tgttagttta gtgaaaacaa
     3601 tcagtaatat tctaggagga gtcttgctag ggattctctc catccagttc atttccttgc
     3661 tgaacgctct taccttttta atcgcatttt taggtatcct tttcataaaa actgacctct
     3721 tgaaagtaga aaaaacgatt aactatcaag aaggactctc tgtaaaatcc ttttgccagc
     3781 atttgctcca atcatcgaaa ttgatatgga atatgaataa ggtgctcttg gttttgttta
     3841 ttatctctac tagtcaagca gtgataaatg ttacagttcc tgtctctact ctatttttga
     3901 ggaatcaacc ctttttgaat ttacaaacag gtcaatctct tgccttgcta tccacttttg
     3961 aactgtcagc cctgattgtc ggaagccttg taagtggcta tctgcaacat accatttcca
     4021 taaaaacagc tctctatgcc tcacttgtca tccagttgct tcttctagta ggatttgcca
     4081 cagttcgttt tgactggatt ctcatcttta gtaccttgga tgcctttttc gcaggtgttc
     4141 tctctcctag attgcaagaa ctcgttttta aacaaatacc tgaggagtca atgggagcag
     4201 ttcaatcctc tatcggtgcc attacggttg ttttacctag cttatttaca atagctttgg
     4261 taaccattgc tactagcttt ggaactctgg cagttagctt tgttttattg ctatttcttc
     4321 tagttgcctt tgttatgctt ctgaatattc gtgaaagtat ttagtggaga atttctataa
     4381 tatatgtttg agactggatt gccagtcttt ttatgatggt caaaatcaac agactttttt
     4441 ctcttttctg aatgtgttat aatagactga atctaaaata gtacgaaaca attgctaaaa
     4501 catttataga aattaatttt actttcccaa tcgatttgtt ctcatcttat ttcaatctgc
     4561 tatataatag tccatgctgt ggctggattc ttttcagcct acttgtactc ttcgaaactc
     4621 tcttcaaacc acgtcagctt cactttgccg taggtatggt tactgacttc gtcagttcta
     4681 tccacaacct caaaacagtg ttttgatctg acttcgtcag ttctatccac aacctcaaaa
     4741 cagtgttttg agctgacttc atcagttcta tctgcaacct caaaacagtg ttttgagcaa
     4801 cctgcggcta gtttcctagt ttgctctttg attttcattg agtattatta agacaatatg
     4861 aggagaaaga tgaaagaaaa aggattttag gagggggcgc aggcagccat gccaacggct
     4921 ctgggctatg tcagtatcgg cctggcctgt gggactatcg gtgcgcccta tgtgacacct
     4981 gttgagatgg gcttgatgag tctctttgtt tatgctggga gtgcccagtt tgccatgttg
     5041 gcactgattg tggttcaagc tcctgtggca gctattgcta tgacggtttt tctaatcaac
     5101 ttgcgtctct ttttgttgag tttacacgca tcgacttatt tccgtcatac cagtctttgg
     5161 tacaatatcg gtatgtctag tatcttgaca gatgagacct atggcgtttt gatgggtgaa
     5221 ttggcccata cagacaaggt aaatcctatg tggatgcacg gaaacaatct taacagctat
     5281 gtggcttggt ttgtggggac agtagtcgga acggctctgg gtggcctgct accaaatcca
     5341 gaaatctttg gcttggattt tgccctggtt gggatgttta ttggtatttt tgcttcgcaa
     5401 tttcagatga tgcaaagacg gattcctgtt cgcaatctgc tcattatctt agcagttgtt
     5461 gcggtgtcct tctttttact tttgacagtg gtgtctcagt cactagctgt tctgtttgcg
     5521 atgctacttg gttgtagcat gggggtggtt ttagatggtc agtaagtatc ttttattagc
     5581 ggttattttc tctggtcttg tgacctggat tccccgtatg attcccttca tcttggtcaa
     5641 gtataagggc ctgcctacga ttgttgagcg ttttttgaag tttttgcctg tttccattat
     5701 ctttgccttg attctttcaa gtgtagtgac aggtaaggtt gggaaccttc ctccaatcaa
     5761 atgactggac ttcttagcag tctttccaat agcttgggta gcctttcgct accgcaatct
     5821 agtcggaaca gttctctttg gagtggtctt gattgccatc ttgcgtttgg tcttttaaat
     5881 tacccataaa aaaaacttat cacagagata gatatcatat aatggcgtaa atgctctttt
     5941 tctgttaaga ttataaggta ttctattttg gaggaaatga catgaaaaaa atcgttaaat
     6001 actcatctct tgctgcccta ggacttgttg ctgcaggtgt gcttgcggct tgctcagggg
     6061 gtgctaagaa agaaggagaa gcagctagca agaaagaaat catcgttgca accaatggat
     6121 caccaaagcc atttatctat gaagaaaatg gcgaattgac tggttatgag attgaagtcg
     6181 ttcgcgctat ctttaaagat tctgacaaat ataatgtcaa gtttgaaaag acagaatggt
     6241 caggtgtctt tgctggtctt gatgctgacc gttacaatat ggctgtcaac aatcttagct
     6301 acactaaaga acgtgcggag aaatacctct atgccgcacc aattgcccaa aatcctaatg
     6361 tccttgtcgt gaagaaagat gactctagta tcaagtctct cgatgatatc ggtggaaaat
     6421 cgacggaagt cgttcaagcc actacatcag ctaagcagtt agaagcatac aacgctgaac
     6481 acacggacaa cccaactatc cttaactata ctaaggcaga cttccaacaa atcatggtac
     6541 gtttgagcga tggacaattt gactacaaga tttttgataa aatcggtgtt gaaacagtta
     6601 tcaagaacca aggtttggac aacttgaaag ttatcgaact tccaagcgac caacaaccgt
     6661 acgtttaccc acttcttgct caaggtcaag atgagttgaa atcgtttgta gacaaacgca
     6721 tcaaagaact ttataaagat ggaactcttg aaaaattgtc taaacaattc ttcggagaca
     6781 cttatctacc ggcagaagct gatattaaat aatttcttga aatcatccat tctgagtaag
     6841 gtgggtggtt tctcagtttt tagggatata gttttaaact atatatctga ctatctaata
     6901 acaatttgtg aaatcaaaca aattgtgaga tactagtacg gtattatttt taaggagaaa
     6961 gaatcatgaa aatcaaaaaa tggcttggtc tagcagccct tgctacagtc gcaggtttgg
     7021 ctcttgcagc ttgcggaaac tcagaaaaga aagcagacaa tgcaacaact atcaaaatcg
     7081 caactgttaa ccgtagcggt tctgaagaaa aacgttggga caaaatccaa gaattggtta
     7141 aaaaagacgg aattaccttg gaatttacag agttcacaga ctattcacaa ccaaacaaag
     7201 caactgctga tggcgaagta gatttgaacg ctttccaaca ctataacttc ttgaacaact
     7261 ggaacaaaga aaacggaaaa gaccttgtag cgattggaga tacttacatc tctccaatcc
     7321 gcctttactc aggtttgaat ggaagtgcca acaagtacac taaagtagaa gacatcccag
     7381 caaacggaga aatcgctgta ccgaatgacg ctacaaacga aagccgtgcg ctttacttgc
     7441 ttcaatcagc tggcttgatt aaattggatg tttctggaac tgctcttgca acagttgcca
     7501 acatcaaaga aaatccaaag aacttgaaaa tcactgaatt ggacgctagc caaacagctc
     7561 gttcattgtc atcagttgac gctgccgttg taaacaatac cttcgttaca gaagcaaaat
     7621 tggactacaa gaaagcactt ttcaaagaac aagctgatga aaactcaaaa caatggtaca
     7681 acatcattgt tgcgaaaaaa gattgggaaa catcacctaa ggctgatgct atcaagaaag
     7741 taatcgcagc ttaccacaca gatgacgtga aaaaagttat cgaagaaaca tcagacggtt
     7801 tggatcaacc agtttggtaa taagaaacag ggaggtggga gagagaattc cacctcttgc
     7861 ttttgtatag agcacggagt gtaaagaaga ctattcgttc atagaaaggt agagagaata
     7921 tggtttttcc tagcgaacaa gaacagattg aaaaatttga aaaggatcat gtagcccagc
     7981 attattttga ggttttgcgt accttgattt ctaagaaatc agtctttgcc cagcaggttg
     8041 gactcaagga agtcgcaaat tatctgggtg agattttcaa gcgtgttgga gctgaagtgg
     8101 agattgatga gagctataca gcgccttttg tcatggcaca tttcaagagt tcgcgtccag
     8161 atgccaagac cttgattttc tataaccact atgacactgt gccagcggat ggggatcagg
     8221 tctggacaga ggatcctttt acgctttcgg tccgcaatgg cttcatgtat gggcgtgggg
     8281 ttgatgacga caagggtcat atcacagctc gcttgagtgc tttgagaaaa tatatgcagc
     8341 accatgatga tttacctgtc aatatcagct ttatcatgga gggagcggag gaatcggctt
     8401 caacagacct agataagtat ttggaaaagc atgcagacaa actccgtggg gcggatttgt
     8461 tggtctggga acaagggacc aaaaatgcct tggaacagct ggaaatttct ggtggcaata
     8521 aggggattgt gacctttgat gccaaggtaa aaagcgctga tgtggatatc cactcgagtt
     8581 atggtggtgt tgtggaatca gctccttggt atctcctcca agccttacag tctcttcgtg
     8641 ctgcggatgg ccgtatcttg gttgaaggct tgtacgaaga agtacaagag cccaatgaac
     8701 gagaaatggc cttgctagaa acttatggtc aacgaaaccc agaggaagtt agtcggattt
     8761 atggattgga gttgcctctc ttacaggagg agcggatggc ctttctaaaa cgtttctttt
     8821 tcgagccagc gcttaatatc gaaggaatcc agtctggtta tcaaggtcag ggtgttaaga
     8881 ctattttacc tgcagaagcc agtgccaagc tagaggttcg tctggttccg ggcctagaac
     8941 cgcatgatgt tctggaaaaa attcggaaac aactagacaa aaatggcttt gataaggtag
     9001 aattatacta taccttggga gagatgagct atcgaagcga tatgagcgca ccagccattc
     9061 tcaatgtgat cgagttggcc aagaaattct atccacaggg cgtttcagtc ttgccgacga
     9121 cagcggggac aggacctatg catacggtct ttgatgccct agaggtacca atggttgcat
     9181 tcggtctagg aaatgccaat agccgagacc acggtggaga tgaaaatgtg cgaatcgctg
     9241 attattacac ccatatcgaa ttagtagagg agctgattag aagctatgag tagagatatt
     9301 atcaagttag atcagatcga tgtgactttt caccaaaaga agagaaccat cacagcggtt
     9361 aaggatgtga ccattcacat ccaagaaggg gatatctacg gaatcgttgg atattctgga
     9421 gcagggaaat caacccttgt acgggtgatt aacctcttgc aaaaaccatc tgcagggaaa
     9481 attaccattg acgacgatgt gatttttgat ggtaaggtca ccttgacggc agagcagttg
     9541 cgtcgtaaac gtcaagatat cgggatgatt ttccagcatt ttaacctgat gagccaaaag
     9601 acagcagagg agaatgtagc ctttgccctt aaacactctg gactcagcaa ggaagaaaag
     9661 aaggctaaag tagctaagtt gttggacttg gttggtttgg cagatcgtgc tgaaaactac
     9721 ccttcacaac tatctggagg gcaaaaacag cgtgtggcaa ttgcgcgtgc cttggccaat
     9781 gatccaaaaa tcttgatttc agacgagtca acttctgccc ttgaccctaa gacaaccaag
     9841 cagattttgg ccttgttgca agatttgaac caaaaattag gcttgacagt tgtcttgatt
     9901 acgcatgaaa tgcagattgt caaagacatt gccaaccgtg tggcggttat gcaggatggg
     9961 catttgattg aagagggaag tgtccttgaa atcttctcaa accctaaaca acctttgact
    10021 caagacttta tctcaacagc cacaggtatt gacgaagcca tggtcaaaat cgagaagcaa
    10081 gaaatcgtgg aacacttgtc tgaaaacagt ctcttggtgc aactcaagta cgctggagct
    10141 tcaacagacg agccactttt gaatgaattg tacaagcatt accaagtaat ggctaatatt
    10201 ctctatggga atatcgaaat tctcgatggt actcctgttg gagaattggt ggtggtcttg
    10261 tcaggtgaaa aagcagcgtt ggcaggtgcc caagaagcta ttctccaagc aggtgtacaa
    10321 ctaaaagtat tgaagggagt acagtaagat ggaatcattg attcaaacct atttaccaaa
    10381 tgtctataaa atgggttggg ctggtcaggc aggctgggga acggctatct acttaactct
    10441 ttatatgaca gttctttcct tcattatcgg aggcttcttg gggctagtgg caggtctctt
    10501 tctcgtcttg acagcgccag gtggtgtctt ggagaataaa gtcgtcttct ggattttaga
    10561 caaaactacc tcaatttttc gtgcagttcc ctttatcatc ctcttggcaa tcttgtcacc
    10621 actttctcac ttgattgtta aaacaagtat cgggccaaat gcagcccttg tcccactttc
    10681 ttttgcagtc tttgccttct ttgcccgtca ggtgcaggtt gtcttggctg aattggatgg
    10741 cggtgtcatt gaggcggctc aagcgagcgg agcgactttc tgggacatcg tgggtgttta
    10801 cctatcagaa ggtcttccag atttgatccg tgtgacgact gtgaccttga tttcccttgt
    10861 tggggaaaca gctatggccg gtgcggttgg agctggtggt atcggtaacg tagccatcgc
    10921 ttatggattt aaccgctaca atcacgatgt gaccatcttg gcaaccatca ttatcatttt
    10981 gattatcttt gcaatccaat tcttgggaga tttcttgact aagaaattga gccataaata
    11041 aaaaagagcc gcgtggctct ttttaactga tcagattttc tgtgcaaatt ttttactcaa
    11101 ggcttgtcca atcaaggcac ccactagggc tccgatgaca atacttgcga taaatagaag
    11161 gacagttcca gggtttggag cgaccatgat gcggtcgata tattcttggg attttcctct
    11221 tgccagaaga gtagccatat aggctttggg cgcaatccac ataagcaaga ttggtcctgt
    11281 tgtactaaag gcgaaaataa tgaaagaaag gaagttcttt gttttgtcct tgtattttcc
    11341 taaatgagct acttcatctg ctaggaggcc acagataatt ccaggaagga aggaaccagc
    11401 accgtgttta gttcccaaga aaaagagggc aatgacaagg ccgatagtgg taatggctcc
    11461 aaagcgcgga acttttgcga ctaggatcat atagacgcta ccgccgacaa gggcagtaaa
    11521 ggcaggcgca taaaacatgt ttccagtttg gtcaaagaga ttgcccaaaa ggacaccaat
    11581 ccccatgcag aggaagtaaa gaactgcaaa aagcagtgta gttaagatag atttcttcat
    11641 gaattgtctc ctgataattt tttcacaatt ctcattttac catggtttgg tgggattgta
    11701 aatggatact agaagttttt gaaaacgctt gaaatatgat ataatggttt catagttatt
    11761 tttaggggaa tatcatgggt agatttttag actttgtctt taatcgtttc tttttaggga
    11821 tgattgcgac agccttcttt tggctattaa ctttagcagg agggattatc cttggtctag
    11881 cgccggctag tgccaccttg atgagcttat atgcagaaca tggttatagc tttcgggaat
    11941 acagtttgaa ggaggcttgg tctctttaca agcaaaattt tgtctcaagc aacctgattt
    12001 tctatagctt tttaggtgtg ggtctagttt tgacctatgg tttgtatctc ttggtgcaat
    12061 tgcctcatca gaccattgtt catttgattg cgaccctttt gaatgtccta gtagttgccc
    12121 tgatcttttt ggcttataca gtatctttaa aattacaagt ttattttgcc ttgtcctatc
    12181 gaaatagtct caaattatcc ttgattggca tctttatgag tctagcagct gtggccaagg
    12241 ttctccttgg gactgtgcta cttgtagcaa ttggttacta tatgcctgcc ctgctatttt
    12301 ttgtaggaat tgggatgtgg catttcttta tcagtgatat gttggaacct gtctatgaaa
    12361 tcatccatga aaaattggcg acaaaataga atgaagcact tttggctaca tacgcttcta
    12421 agaacctata gttcagtgat gatcattatc attgcgagtt ttgcaatctt actctcttac
    12481 gctgactggg attcacgtga aaaggaagcc cagagagtag cccagcgtgt aactgctaga
    12541 acagtgagtg aaattgaata ttaccataga gagtcaaccc agatagctca ggctttagtt
    12601 gaaaatcaag ctcgtatcga gggaatctat aaatacttta gccttagcat gccagactat
    12661 ttttactggc aattagagcg gaaagcttcg ccttatatat cagtctctct gtatgaaaat
    12721 gttgatgacc tctatgttcg aaatgatttt gtaactgggg tggccattgc ttttcaagat
    12781 tacaaggaag tctatgtttc tactaaagac aaacgtagtg gagaaaaaat cagggctgag
    12841 gatttcaaac cagcaggaaa tagttttgcc attccagtgt cagatccagt gtcagatcaa
    12901 gacttaggag tgatttacat ctccttggat cctgctgttc tataccatgc cattgataat
    12961 actagaggtc atactccgat ggcagtaaca gtgacctcac cttttgatac ggagattttt
    13021 catattggtg agacagttga taaggagagt gaaaattggc tagttggctt aacttctcat
    13081 ggttatcagg ttcaggtggc agttcccaaa aactttgttt tacaaggaac ggtgaccagc
    13141 tctgctttga ttgtgggctt gagccttctc tttattgtca ttctttatct gactttgagg
    13201 cagacctttg ctaattatca aaagcaggta gtggatttgg tggattccat ccaagctatt
    13261 gcccaaggac aagaaggtct tcgcattgat acgcttgaaa aggatcagga attgctccta
    13321 atcgcggaga cgaccaatga tatgttggat cgattggaaa agaatatcca tgatatttac
    13381 cagttagagc ttagtcaaaa agatgccaat atgcgagcct tgcaggcgca aatcaatcct
    13441 cattttatgt ataatacgct ggagttcttg cgcatgtatg cagttatgca gagtcaagat
    13501 gagttggcag atatcattta tgaattcagt agtctcttgc gtaacaatat ttccgacgaa
    13561 agagagaccc tcctcaaaca ggaattagaa ttttgccgta aatacagcta tctctgcatg
    13621 gttcgctatc ccaagtccat tgcctatggt ttcaagatag atccagagtt agagaatatg
    13681 aagattccca agtttacctt gcaaccgctg gtagaaaact atttcgcgca tggtgttgac
    13741 cacaggcgga cagataatgt gattagcatc aaggctctta aacaggatgg ttttgtggaa
    13801 attttggtgg tcgataatgg tagaggaatg tcggctgaaa agttggcaaa tatccgagaa
    13861 aaattaagtc agaaatattt tgaacaccaa gccagctaca gtgatcaaag gcagtctatc
    13921 ggaattatca atgtacacga gcgttttgtg ctctattttg gagaccgcta tgccattacg
    13981 atagagtctg cagagcaagc cggtgttcag tatcgtatta caattcaaga tgagtagaaa
    14041 gggagaaaat gtataaagta ttattagtag atgatgagta catggtgaca gaaggtctga
    14101 agcgtttgat tccctttgat aagtgggata tggaggtcgt cgcaacagcc agtcatgccg
    14161 atgaagctct agaatatgtt caggaaaatc ctgtcgatgt catcatttcc gatgtcaata
    14221 tgccagacaa aacagggctt gatatgattc gggagatgaa agagatctta ccagatgctg
    14281 cctatatcct gctctcaggt tatcaggagt ttgattatgt aaaaagagca atgaacctta
    14341 gtgtggtgga ctatttggtc aagcctgttg ataaggtaga gctgggaaat ctgctggaga
    14401 agattgcagg tcagctcggc gagagaggga agaaaagtca gactcttagt caagaattag
    14461 acgaggctgg atttgttagt tatttagggg ataaggagaa ttggtggata ggtctatcca
    14521 aggaaaaaca aggttccttc accattccct actatgtctt gggccaagac tggcagattt
    14581 tcatttctga ccaaccccta gatggtttag tcgttacacc ttttgaagct ccttatcaag
    14641 aacactttga acgctggaag ctgaatgctg agaaaaccct cttttacggt tctgtaaatt
    14701 tgcagcagtc tgagagtctc tttgcctatt acgaaccgat ttatagggtt atcattcagg
    14761 gaaatctcaa tcaaatcgta gaagagttaa atctcttgga gaaggtagtt cttgaaaata
    14821 cgccgcgtgt tccgattact aaacagcttt ttattcagtt tgtcatggat gttttccatt
    14881 tatttgaaca tctcaaagct gatgacctga cagacatcgt caaaaccatt catgctattc
    14941 aatccttcga tgaattggtt ccttatatca aggaaactct gagcagcttt ttcggtcaat
    15001 accgtatgaa tgaaaatgtg gccagtgtgc tggaagtcat tggtcgtgat taccaaaaag
    15061 agctttccct caaggatatc agtaaggctc tctttatcaa tcctgtctat ctagggcagt
    15121 tgattaagcg tgaaaccgat tcgacttttg cagagttact aaacaaacaa cgtattaagg
    15181 ctgcccaaca acttttgctt tcaactagtg acagcatcga agatatttgt tatgctgttg
    15241 gttacagtaa ccttggatat ttctataaag ttttccgaaa attgtgcgga aaatcgccaa
    15301 aagcctaccg aaaacaggta gaaactatac tataagattt gtattccttt acaaaatgtg
    15361 ctataatata aatattatta ttaggaggtt ctatcatgaa aaagaaacca atttatctat
    15421 gggtcttgct aatcttgtct gcccttattt cagttccgtc tctgtttgga attgtgagtc
    15481 ccttgcctag taaagaagcc cttcgtgctg ctcagaaaca agttgcaggg gtcaatgctc
    15541 agcaattaga agaccagctt aattatacct atagagtagc agaagcatct cattctattt
    15601 ttaatgttgc tttgattgtg ctatctacta ttttagtggt cgtagcgatt gtcttccttg
    15661 ttcgtaaaaa tttgcaatat gcaaactata cttacgttgg ctatgttttg ttagctatta
    15721 ttggttcgat ttatggctat gttggtttac aagacgctgt gcagttggtt caagatgaga
    15781 gcatgcgttt gacagtgagt attggttcaa aagctgttag cattttctat atcgtcatca
    15841 atgttctctt cctagccctt gtcttctata agatgtggcg acaacagaaa gccttggcag
    15901 aagaagagga aacagaagag cttacctaag tattgacaaa aaagaactat caagatacaa
    15961 tcttggtagt tgttttttga ttatagataa aatcatggag gtacatatga agacaatttc
    16021 tttagtttat attagtttga gtggcaacac tgaaagtttt gtgacgcgct tgaaagacta
    16081 tctcttgtcc cagtacaaag ggattgaggt tcaaaagatt catatcaagg atttggtcaa
    16141 ggaaggcaaa aatttctatg aaatggacca tccctatgtc gcttttttgc cgacctatct
    16201 cgaaggtggg aatggcgtgg ataacggaga tgttgagatt ttgacgacac cggtgggaga
    16261 ttttattgcc tatggtaaca atgctagtaa gtgttttggt gtggttgggt caggaaatcg
    16321 taactttaat aaccaatact gcctaacagc caagcaatac agtcaacgct ttggcttccc
    16381 tgtattggct gactttgaaa tgcgaggcat gctggaagat atcaaacatg tcgcagctat
    16441 tatcgcagat ttgtatgagt tggaaaagga gaattaatac tcaatgaaaa tcaaagagca
    16501 aactaggaag ctagtcgcag gttgctcaaa gcacagcttt gaggttgcag atagagctga
    16561 cgtggtttga agagattctc gaatagtata aagttcttat aagatgtggt tgaagttgtt
    16621 caactgtttt ttgagtataa acagtcttta agaacgtaaa aaagcataag ttcaggtctt
    16681 caaaaccttg ttcttatgct ttttatcata gaaatatttg ctgaattttc tcttgaaatg
    16741 aaaccttatc ttcatctcgc gcttgtccct taccctgctt ttccgattgc gagtgcgtag
    16801 ataaagaaga tggcgaagcc aaagaggaaa atcaatcccg caatggcaag gtgtttgagc
    16861 caagaaggaa gatttttgtt ttcacgtgtt accaaggcgt aattcaaaag agcaaagaaa
    16921 ggtgttgtca ggaaagagcc aatcatggca aagcggagca tggttgaaac ctgaccagcg
    16981 aagaacttga taatgatgat accgatgata gcagtgatgg tcatccagat gttcaaagat
    17041 ttacgattgt cctctttttg actgattagc agtcggagag attcctgatt aacgcgagaa
    17101 tagccatcga taacagttat aactgttcca aagatacaga ggaaggcaat aaaagtaatc
    17161 aagtaacggg accattcgcc aagaacagag gcatacatgc ccacgaattg agagatgtat
    17221 ttggctgaag cagcttcaac cgcctgccct gtaggatact gaatcagtgc tcccagtgcc
    17281 acaaagaaga cggctaggat agctgttcca atataaccag tgttaaagtc aaacagagcg
    17341 tcttctgtgt taaagttgac ggtctttctc ttttcagctg accaaagtga attgatagct
    17401 gaaatttcaa taggagccgg catccatcct aggagggaga cgatgaaggg cagagctgcc
    17461 atttgccaag gtgtcttctc gacaaaatca gaactgtatt ctggatgctt gaccgccgct
    17521 atgataactg caagaacagt cgcaatggtt aaggcagaca taatccattt gaccatgccg
    17581 tctaaaagtt tgtagcctcc aaagagtagc atagcccaaa tgattgcaac gagaatgagg
    17641 gaccactgag taatgctaag tccaatcatt gggaaggcac tggcgatgat agctgagcac
    17701 agaatggcaa caccagccgt gttgaccata gccgaaaaga cattgaggat aaagaaaatc
    17761 cagagataga gttttccttt ttcggcataa ccttcaacca aagtctttcc agtatcagct
    17821 gtgtattcag caccaaaacg gaaaaatgga tatttaaaga cattggctaa gatgaccaag
    17881 agaagtagag accaaccgta agaaccgcca gcttgagttg aggatacaat gtgggaacct
    17941 ccaacagcgg cagttgccat taggattcca ggtcccattg cttttagctt gcttgcccag
    18001 gttgattgat ttaaggaaat agcttgcgac atgataaata ctcctttttg aattttcaga
    18061 ataatctgta tatgtaatct atattctaca aaaaattttg gaaaaatgca agaatatttt
    18121 gaaaaaagat agaaaattta caaagaaaat ctgaaataac tgttatgata tagcagattg
    18181 aaactagaat agtacacctt tgcttctaaa acattgttag aaatcgattt gactgtcctg
    18241 atcgatttat cctgttctta tttcatttca ctatagtaag gtgcagcagg ataaagaaaa
    18301 accgagaagt ttctttctcg gatttgctta ttatgaggtg cctattttct atgctccaag
    18361 agttgattga tgtgatctac ttttttagcc tctcttttat agagaatagc ccagatgatg
    18421 agatagacaa tcgcaaactc gataatgagc tggaggtaga aaatccagtg gaaggggaac
    18481 caaccagcaa gagttgctag tgggacaaag ccagccagca taaggaagaa atgagtcaga
    18541 gtggcacgaa gcatgctcca gtcacggctg aataagcagt tgccaaagtt gaagagcata
    18601 ccgatggctg cccagataag tgtgcagtag agcaagacca gggcaccgtg aacctgatgc
    18661 tgatccatca cttggccgat gagagagtag ggatttagtg gtgcgtaggt atttggtgca
    18721 taaatgagtg aaaagaggat ggagaggatg aggccgataa gaacaccggc agctgcatcg
    18781 tgaaatactt gttttttcat agttctaatt tctccttgat ggtttttaga taacggcgtg
    18841 aagagtaggt gaagctttcg tttttcaaga aaatttctac cagaccgttt ggcgtgagct
    18901 tgaggtgaga gatggaatcg atattgatga tttctgattg ggaaatttgg ataaaattgc
    18961 ttggcaagag tttaagaacc tgatagagtc gcaaatcaat gctgtaggtc tgactcgtgg
    19021 tttctgctag aaccttccga ttctcgatat agaagcgctg aatcttgcca atctcaacta
    19081 gatagacctg atcatcgatt tttcctttga ttttttctct ttggtccaga ttttctgcga
    19141 actcgatgac tttctggact ttttcggttt cttgaggtgc ttggacaatc agcttttcct
    19201 cctcgtaagt ctcactaatc tgtagttcta ctttcataaa tttctctcct tgtttttcat
    19261 acaaaattaa tctcacttct tgtacacctt tattaatact cttcaaaaat ctcttcaaac
    19321 cacgtcagca tcgtcttgcc gtaggatagt tgttgacttt gtcaatttta tctacaacct
    19381 caaaacagtg ttttgagctg tctgcgccta gctttctagt ttgctctttg atttttattg
    19441 agtataccac tattttactc cctctggcaa ggtactttgt ctatgtggag ggattgggct
    19501 cctatgtggt ggagcttttc tgttctttct gaaatatggt ataatagcac taatcaattt
    19561 ctaggaaaat agatacagaa aggggctgaa agatgtctca tattattgaa ttgccagaga
    19621 tgctggcaaa ccaaatcgcg gctggagagg tcattgaacg tcctgccagt gtggtcaaag
    19681 agttggtaga aaatgccatt gacgcgggct ctagtcagat tatcattgag attgaggaag
    19741 ctggtctcaa gaaggttcaa atcacagata acggttatgg aatttcccac gatgaggtgg
    19801 agttggccct gcgtcgccat gcgaccagta agataaaaaa tcaagcagat ctctttcgga
    19861 ttcggacgct tggttttcgt ggtgaagcct tgccttctat tgcgtctgtt agtgtcttga
    19921 ctctgttaac ggcggtggat ggtgctagtc atggaaccaa gttagtcgcg cgtgggggtg
    19981 aagttgagga agtcatccca gcgactagtc ctgtgggaac caaggtttgt gtggaggatc
    20041 tctttttcaa cacgcctgcc cgtctcaagt atatgaagag ccagcaagcg gagttgtctc
    20101 atatcattga tattgtcaac cgtctgggct tggcccatcc tgagatttct tttagcttga
    20161 ttagtgatgg caaggaaatg acgcggacag cagggactgg tcaattgcgc caagcaatcg
    20221 cagggattta cggtttggtc agtgccaaga agatgattgc tattgaaaac tctgacttag
    20281 atttcgaaat ttctggcttt gtgtccttgc ctgagttgac tcgggctaac cgcaattata
    20341 tcagcctctt catcaatggc cgttatatca agaacttcct gctcaatcgt gctattttgg
    20401 atggtttcgg aagcaagctt atggttggac gttttccact ggctgtcatt cacatccata
    20461 tcgaccctta tctagcggat gtcaatgtgc atccaactaa gcaagaggtg cggatttcca
    20521 aggaaaaaga actgatgact ctggtttcag aagctattgc aaatagtctc aaggaacaaa
    20581 ccttgattcc agatgccttg gaaaatcttg ccaaatcgac cgtgcgcaat cgtgagaagg
    20641 tggagcaaac tattctccca ctcaaagaaa atacgctcta ctatgagaaa actgagccgt
    20701 caagacctag tcaaactgaa gtagctgatt atcaggtaga attgactgat gaagggcagg
    20761 atttgaccct gtttgccaag gaaaccttgg accgattgac caagccagca aaactgcatt
    20821 ttgcagagag aaagcctgct aactacgacc agctagacca tccagagtta gatcttgcta
    20881 gcatcgataa ggcttatgac aaactggagc gagaagaagc atccagcttc ccagagttgg
    20941 agtttttcgg acaaatgcac gggacttatc tctttgccca agggcgagat ggactttaca
    21001 tcatagatca gcacgctgct caggaacggg tcaagtacga ggagtaccgt gaaagcattg
    21061 gcaatgttga ccaaagccag cagcaactcc tagtgcccta tatctttgaa tttcctgcgg
    21121 atgatgccct gcgtctcaag gaaagaatgc ctctcttaga ggaagtgggc gtctttctag
    21181 cagagtacgg agaaaatcaa tttattctac gtgaacatcc tatttggatg gcagaagaag
    21241 agattgaatc aggcatctat gagatgtgcg acatgctcct tttgaccaag gaagtttcta
    21301 tcaagaaata ccgagcagag ctggctatca tgatgtcttg caagcgatct atcaaggcca
    21361 atcatcgtat tgatgatcat tcagctagac aactcctcta tcagctttct caatgtgaca
    21421 atccctataa ctgtcctcac ggacgtcctg ttttggtgca ttttaccaag tcggatatgg
    21481 aaaagatgtt ccgacgtatt caggaaaatc acaccagtct ccgtgagttg gggaaatatt
    21541 aaaagtataa aaaagtctgg gaaaaatttt caaaatcaaa aaaacgcata aaatcaggtg
    21601 ttcaaaaacc ttgattttat gcgttttatc atggaaatag ttacttcatt ttttcctaat
    21661 tcttttcgaa actcttttta aaccacgtca gttttatcag taatctcaaa acagtgtttt
    21721 gagctaattt tgccagtttt gtctgtaaca tcgaagttgt gttttaccac tctgcgactg
    21781 gtttcctagt ttgctctatg attttcacag agtattaaat tgcgattttg ccaagtttct
    21841 ttattcgtct aaaagtagag tctgttctat gcgtctaatg tacgaatcag gttgaccatt
    21901 tcaatagctc cttgtgcaca ctcagaaccc ttatttcctg ctttagtacc agctcgttct
    21961 atggcttgtt caattgtatc tgtcgttagc acaccaaaca taacaggaat ttcgctattt
    22021 aaactgattt gggcgattcc cttagatacc tcgctacata cataatcata atgacttgta
    22081 ttccctctaa tgacagctcc caagcagata attgcatcat attttttact ttttgccatt
    22141 tttgatgcaa tcagtggtat ttcaaaagct cctggaaccc aggctacctc tatatctttc
    22201 tcgtttacat tctctctttt gagattatct agtgctccag ataataattt tgaagttata
    22261 aattcattaa atctcgctac aacaatacct attttaatat tgtttgctac taaattacct
    22321 tcataagtgt tcatttattt ttcctccata tttaaaatgt gacccattcg atttttcttt
    22381 gtttctaaat aaaaactatc gtaaggattg gcttctattt cgattgatat tctactggaa
    22441 atggtaattc catatttttc taactgttca accttgtcag gattatttgt cagtaaatga
    22501 agtgactgaa gtcccagatc tttaagcatt tgtgctccaa tatgatattc tcttaaatca
    22561 ccttcaaagc ctaatgcaag attggcatca agcgtatcca tgccttgatc ttgtaaatga
    22621 taggctttta atttattgat aagtccaatt cctcgtccct cctgtcgcaa gtaaagtaag
    22681 acacccgaac cattctcaac aatcattttc atagctttat cgaattgctg tccacaatcg
    22741 caacgtaagg agcctaaaac atcccctgtt aaacattcgg agtggacccg acataataca
    22801 ttggcttcat cctctatgtt tcccataata agagcaagat gatgttcccc atttagttta
    22861 tctatatagc taattgcttt gaaattaccg tatctagtag gcatattgac agttgaaact
    22921 cgttctacca gctgatcata tacttttcta tattcttgta attctttgat ggtaattagt
    22981 ggaatgttgt gtttcttcga gaactgaatt aaatcatctg ttctcatcat tttgccatca
    23041 tgattcatta tttcacaaca taggccacac tcttttagtc cagctaattt taataaatca
    23101 acagttgctt ctgtgtgtcc acttctttct agaacaccac ctttttttgc aattaaagga
    23161 aacatgtgtc ctggcctgcg aaaatcagag ggtgttatat cttcagctac acacatacgt
    23221 gcggtcagtc ctctttcctc ggcagaaata cctgtggtcg tttctttata atcaattgaa
    23281 actgtaaaag cagtcttatg attatctgta ttgttttcaa ccataggtga aagcattaat
    23341 tgattagcta aactttcgct cataggcata caaattaatc ctttggcata agtagccata
    23401 aaattaacat tttctgttgt agctgcttgt gcagaacaaa ttaagtctcc ttcattttct
    23461 ctatccttgt cgtctataac aagaacaagt cgtcccttct gcaatgcttc taatgcttct
    23521 tgtatttttc gatattccat tgactgatta tcctttctgc taaaatccat tttgatataa
    23581 tagttcctta gatatttctg attttggaga gttatccatc agtttttgca catatttacc
    23641 taagatatca ttttcaagat ttactgtact cccgacttgt ttactcttaa gaatggtttg
    23701 ttccaaggta tgagggataa cagatactga aaagtttact ttggagactt tagcgacagt
    23761 cagactaatg ccgtcaattg taatagatcc tttttcaact attaaatcta aaatttcttt
    23821 ttgtgtgttg atttgatacc atacagcatt atcatctttt tttattgacg agatttttcc
    23881 tgtaccatca atgtgtcctg taacgacgtg acccccaagt cgaccgttga tagataaggc
    23941 tctttctaga ttcacctcac ttccatgttt taatagagta agagctgttc gactccatgt
    24001 ttcattcatt acatcaactg taaaggattg atgattgaaa tgagtaactg taagacagat
    24061 accatttact gctatactat cgcctaaatg gatatccgtt aatatttttg aggctttaat
    24121 tgatagttta caattacgag agtctttctg tattctttca acttttccga tttcttcaat
    24181 tattcctgtg aacatggata aatcacttca ctttctatga gatagtcatt tcctatttga
    24241 gaaaaagcat aaggtttcaa tctaatagcg tcatttggca aagaaatgcc ttcacctccg
    24301 acaggaaact tggcactgcc tccaaaaatt tttggtgcaa tatatatttt cagctcatca
    24361 acaatttgtt gttccaaagc actccaattc attagactgc ccccttctag aactaggcta
    24421 tcaatctgca tgtttcctag atgttgcatt aaactcgata agtctatatg attgcctttt
    24481 ttctttatgg aaagtatttc acagccatga ttttgatata gcttcatttt atttttgtct
    24541 tcagaggaag tggcaatgta agttttaata tcatttgctg tttttacgat tttagaggta
    24601 agaggagttc gtaaatgtgt atcgcatatg atacggatag gatttttccc ttcctccaat
    24661 ctacatgtca gcaaaggatc gtcttgaata acagtattga ctcccaccat aattgcacta
    24721 acatggtgtc gtaactgatg cacatgcttt cttgcttctt cttcagtaat ccatttggat
    24781 tgatttgttt tagtggctat ttttccatcc attgacattg catatttcat aaaaacatag
    24841 ggtacatgct gggtaatata ctttctaaaa ctttttatta agttaagaca ctcattttct
    24901 aaaattccaa cagtaacttg aagattattt tcctcaagta tctttactcc ttttccagat
    24961 acaataggat tacagtctag gcttccaatg actactcttg taataccact atcgattata
    25021 gcatctatac agggaggtgt tttcccgaag tgacaacagg gttcaagtgt tacataaagc
    25081 gtcgctccga caggggattc tctacagttt ttaagagcat ttctctcagc atgtgggcca
    25141 ccaaaaaact catgataacc ttgtccgatg atgtgattat cttttacaat aactgcgccg
    25201 accataggat tggggttgac gtaaccagcc cctttttgtg ccagttttat tgctaatttc
    25261 atatattttg aatcgctcat ctcactacct ccaaaaaata taccttgaat aggggactac
    25321 tcaaggcata caaaagaaaa cttatgcgat taacaaaaat gctctgaaat gacaagtaat
    25381 catttcagag cacgcaaaaa gcacaaatat acttttatct tctttcatcc agactatact
    25441 gtcggctttg gaatttcacc aaatcatgcc tttcggctcg tgggctatac caccggtagg
    25501 gaattgcacc ctgccctgaa gatagttatt caattacaga tgattatagt acttaatttt
    25561 gaatatgtca acagataaat atcgattgtt tttgatatac tgtatttgtg ataatcgatt
    25621 ctcgctcctc ggataaagaa aatatgatat actagataaa cgaaataaga gagaaggaac
    25681 actatgtacg catatttaaa aggaatcatt accaaaatta ctgccaaata cattgttctt
    25741 gaaaccaatg gtattggtta tatcctgcat gtggccaatc cttatgccta ttcaggtcag
    25801 gttaatcagg aggatcagat ttatgtgcat caggttgtgc gtgaggacgc ccatttgctt
    25861 tatggatttc gctcagagga tgagaaaaag ctctttctta gtctgatttc ggtctctggg
    25921 attggtcctg tatcagctct tgctattatc gctgctgatg acaatgctgg cttggttcaa
    25981 gccattgaaa ccaagaacat cacctacttg accaagttcc ctaaaattgg caagaaaaca
    26041 gcccagcaga tggtgctgga cttggaaggc aaggtagtag ttgcaggaga tgaccttcct
    26101 gccaaggtcg cagtgcaagc aagtgctgaa aaccaagaat tggaagaagc tatggaagcc
    26161 atgttggctc tgggctacaa ggcaacagag ctcaagaaaa tcaagaaatt ctttgaagga
    26221 acgacagata cagctgagaa ctatatcaag tcggccctta aaatgttggt caaataggag
    26281 cagagaatga caaaacgttg ttcgtgggtc aagatgacca acccgctcta catcgcctat
    26341 catgatgagg agtggggtca gcccctccat gatgaccaag cattgtttga gttgttgtgt
    26401 atggaaacct atcaggcagg cctgtcttgg gaaacggtac tcaacaaacg ccaagctttc
    26461 cgagaagcct ttcatagcta tcaaattcac tcagtcgcag agatgactga cactgaattg
    26521 gaagccatac tggagaatcc agctatcatt cgaaatagag ccaagatttt tgctacacgc
    26581 gctaacgccc aagcctttct acagttacag gcagagtacg gctcttttga tgcctatctt
    26641 tggtcttttg ttgaggggaa aactgtcgtt aacgatgttc ctgattatcg ccaagcccca
    26701 gctaaaacac ccttatctga gaaattagcc aaagatctca aaaaacgagg cttcaagttc
    26761 acaggcccag tcgccgtatt gtcttttcta caggctgcag ggctagttga tgaccacgag
    26821 aatgattgtg agtggagagg tcttaaatga tgtctaacaa aaataaggga attctgattt
    26881 ttgcgattct ctatacagtc ctctttgtgt ttgatggcgt taaattgctg gcttctttaa
    26941 tgccatctgt cattgcaaat tatcttgttt atgtagtttt agctctatat ggctccttct
    27001 tgttcaagga tagattgatc caacaatgga aggagattag aaagactaaa agaaaattct
    27061 tctttggcgt cttaacagga tggctctttc tcattctgat gactgttgtc tttgaatttg
    27121 tatcagagat gttgaagcag tttgtgggac tagatggaca aggtctaaat cagtctaata
    27181 ttcaaagtac ctttcaagaa caaccactac tgatagctgt ttttgcttgt gtcattggac
    27241 ctctggtaga agaattattt ttccgtcagg tcttattgca ttacttgcag gaacggttgc
    27301 caggtttact aagcattatt ctggtaggac ttgtttttgc tctgactcat atgcacagtt
    27361 tggctctatc agagtggatt ggtgcagttg gttacttagg tggaggcctt gccttttcta
    27421 ttatttatgt gaaagaaaaa gagaatatct actatcccct acttgttcac atgttaagca
    27481 acagcctctc cttaatcatt ttagctatca gtatagtaaa atgaaataag aacaggacaa
    27541 atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc
    27601 tagtttcaat ttgctgtaat atgtgatgaa aataccagta atgataccga gaaaaaagct
    27661 gagaaacttt tcccagcttt atttgttata gtcaaagcga atgacttgtt cctgtgcatc
    27721 tacatgagca tggaccccaa agggtacaat tgctcttgga gttgcgtggc cgacattcag
    27781 attatagaca atcgggatat tgctgtcaat gatatccaat agtgcctctt tatagtcgtc
    27841 atggaaagtt tcatccatag gttttccgac caagagtcca ttgatgaccg cgaatatgcc
    27901 agtgtccttt aaagttagca acatcttttt gaagtcttct ggcttaggct tttcttcgct
    27961 tgtttcgagc aagaggattt tcccttccca gtctgacaag tcagggaaaa gtttgtattt
    28021 ttggcagagt tccgtgctat ctgcgtatcg agagttgtca aagatatcgt agagggattc
    28081 gaggcaacca ccgaggattt ttccctcgaa ctgagcactt ccttgcaaca agtcaaaacc
    28141 tgtatttgta tgactgacac gaggtgttcc cagggccgtg ggactaaaat cagttcgttc
    28201 ctcataccaa acgtcactag ggcggatttc tgaaattctt cccgtcttaa tcaattcttt
    28261 aaagtagtga aggctatagg ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa
    28321 ggattgacca taaaaagtct tgattcctaa tttatgcaac atgaggtggt tcatggttgt
    28381 atccgagaag ccaagaaaaa ttttttgctt gataaccttt tggagttggt cattttcaaa
    28441 aagataaggt agcaagcgat aggtatcgtc tccaccgatg gcacatagga tcatgtcgat
    28501 gctatcatca gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat ggtccttgat
    28561 aaagtctaat ccttttaacg aatgggacaa aaagatggga ttgagtccca gatccttgag
    28621 acgttggata cccaagtcca cttcgtgttt gacaaaatcc tctccgataa tgccactaga
    28681 taaactaaca ataccaatag tagaaaccat atctcatcct cctagaaata gattgagcct
    28741 attttatcac aaaatataag agaaagctat gtgggatttc agaagaatac ttttaatact
    28801 cttcgaaaat ctcttcaaac cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag
    28861 caacctgcag ctagcttcct agtttgctct ttgattttca ttgaatataa ctcaaaaaag
    28921 taagtgaaaa agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt
    28981 gttggtcctg cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct
    29041 aggagggctg ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct
    29101 ggtaggaagc ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact
    29161 agtacagatt tccagaaagg tggacgttga ctgcgatcca tatctgatcc atagtattgg
    29221 taaacaaagt agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga
    29281 gtaatcaatc catagccgaa agcttggtct gccgcaaaga aggttgtgag ggcgctgaca
    29341 agggcaaaga ggctagtgat gaaaagagct gagtccataa tcatcagttt tgggtcatca
    29401 ttttcttttg gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga
    29461 gttggtgcgc cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg
    29521 ggaatgactt cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat
    29581 tgttgggtag caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt
    29641 tgagacatag gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga
    29701 cactcatagc aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg
    29761 ggatttcatt atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca
    29821 tgacgatggt cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag
    29881 aggcaaaggt ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg
    29941 cctgttgggt ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga
    30001 tattgctggt tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct
    30061 tgaaatagac gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg
    30121 attgatgcag ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta
    30181 ggtaaagctc tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat
    30241 agaaattacg caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg
    30301 tagtgataat ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc
    30361 ggttatttct ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa
    30421 tggtaatacg agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat
    30481 cgaaggtgtt ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag
    30541 tacccggttc aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt
    30601 tcatatccct tatcctttct catttttcag attttttcac actgtactat tatactacaa
    30661 aatcggcctt ttgggtaata gaatctcact ttttttggta taatggtaag caataatgga
    30721 ctagaaagaa caaagatgca agataaaatt gtcattcatg gggcgcgtgc ccataattta
    30781 aaaaatattg atgtggagat tccgcgagac aagttggttg tcgtgactgg cttgtcaggt
    30841 tcagggaagt ccagtctggc ttttgatact ctctatgcgg agggacaacg tcgctatgta
    30901 gagagtttgt ccgcctacgc tcgtcagttc ttgggaaata tggaaaaacc agatgtagat
    30961 gccattgatg gtctcagccc agctatttcc atcgaccaga aaacgactag taaaaatcct
    31021 cgctcgacgg tgggaacgac gactgaaatc aatgactatc tgcgtctcct ctacgcacgt
    31081 gtggggacgc cttactgtat caacggacat ggagctatca atgcttcttc tgtggagcaa
    31141 atcgttgata aggttttgga gttacctgaa cgccagcgct tgcagatctt ggctcctgtc
    31201 atccgcaaga aaaaaggcca acataagagt gttatcgaga aggttcagaa agacgggtat
    31261 gttcgtgtcc gtgtggatgg ggaagtctat gatgtgaccg aagtgccaga gttgtctaag
    31321 agcaagcaac acaatatcga tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt
    31381 agtcgtctct ttgattccat tgaggctgcc cttcgtattg cagaaggtta tgtcattatc
    31441 gacaccatgg acgactcgga gttgctcttc tctgagcatt atgcctgtcc agtttgtgga
    31501 tttactgtcc cagagttaga acctcgtctc ttctctttca atgctccctt tggctcttgt
    31561 agtgagtgtg acggcttggg gattaagctg gaggtggata ctgatttggt agtgccagat
    31621 gccagcaaaa ccttacatga gggagcgctg gcaccttgga atcctatctc atccaactac
    31681 tatccaaaca tgttagagca ggccatgaaa gtctttggag tggctatgga taagcctttt
    31741 gaggacctgt cagaagaaga taagaacttg attctctacg gctcagatgg taaggaattc
    31801 catttccatt atgaaaatga atttggtggt gtgcgcgata tcgacattcc gtttgaggga
    31861 gttatcaata atatcaaacg tcgttaccat gaaaccaata gcgattacac tcgcactcag
    31921 atgcgtctct acatgaatga gctgacctgc ggaacctgtc aaggctatcg tctcaatgac
    31981 caggccttgt ctgtccgtgt gggcggccag caagggccac atattggaga aatctcagac
    32041 ctgtctatcg ctgaccactt ggacttggtg agccagttaa ctttgtctga aaatgaagcc
    32101 atcattgctc gtcccattct caaggaaatc aaggatcgtt tgaccttcct taataatgtg
    32161 ggtcttaact atctaaccct gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag
    32221 cgcattcgtt tggcaaccca gattggttcc aacctatcag gtgtcctcta tatcctagac
    32281 gagccgtcaa tcggtcttca ccagagggac aatgaccgcc tgattgccag tctgaaaaag
    32341 atgcgtgact tgggcaatac tcttatcgtg gtggaacacg acgaagatac catgcgtgaa
    32401 gctgattatc tgattgacgt tggtcctggt gccggtgttt ttggtggtga gattgttgca
    32461 gcaggtacac ctaagcaagt ggctcgcaac agcaagtcta tcacaggtca gtacttgtca
    32521 ggcaaacgtg tcatcccagt accagaagag cgccgtgtcg gaaatggtcg ttttattgaa
    32581 gtgacaggag cgcgtgagaa caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa
    32641 tttatcgcag tgacaggtgt gtcgggttca gggaaatcga ctctaatcaa cagcattctc
    32701 aaaaaagcca ttgcccagaa gctcaaccgt aattcagaca aacctggtaa gtttaagact
    32761 attacaggga ttgagcatgt cgaccgtttg attgatattg accagagccc tatcggacgg
    32821 acgccgaggt ctaacccagc tacctataca ggagtttttg acgatatacg tgaccttttt
    32881 gctcagacaa atgaagccaa gattcgaggc tacaagaagg ggcgcttcag tttcaacgtc
    32941 aagggaggtc gctgtgaagc ttgctcaggt gacgggatta tcaagattga gatgcacttc
    33001 ttgccagatg tttatgtggc ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc
    33061 ctagaagttc actacaagga aaagaatatt tcgcaggtct tggatatgac ggtcaacgat
    33121 gcggtagaat ttttccaaca cattccgaaa attcaacgca aactccagac catcaaggat
    33181 gtaggtctag gctatgtgac cttgggacag ccagctacca ccctttctgg gggagaagcc
    33241 caacgtatga agttagctag cgaactccac aaacgctcga caggaaaatc tttctacatt
    33301 ctggatgagc cgacgacagg gcttcataca gaggacattg ctcgcctgct caaggtttta
    33361 gctcgctttg tagacgccgg caatacagtc ctcgtcatcg agcacaatct ggatgttatc
    33421 aagacggcag accatatcat tgacttggga cctgagggcg gtgtcggtgg tggaaccatc
    33481 atcgtaacag gaactccaga agaagtagct gccaacgaag ccagctacac aggacactat
    33541 ttgaaaggaa agttacatca tgaataaacg cgtacaagca tttctagcta aaatgcaaga
    33601 aaaagaacta gatggtatca tcatcaacaa tcttaaaaac gtctattatt tgactggttt
    33661 ttggggctca aacggaacag tctttatcag ccgtgaccgt caggtcttag tgacagactc
    33721 tcgctatatc atcgcagcta agcaagaaac cagtggtttt gagattgtgg ctgatcgtga
    33781 tgaattggct gtcattgcag gaattgttaa ggacatgaac ttgactcgta tcggttttga
    33841 agatgagatt tcagtgtctt attaccaccg tatgcaggca gcttttgcag gtttgaactt
    33901 gcttccacaa actcagtttg tggaaggtct tcgtatgatt aaggatgagg cagagattgc
    33961 agcgattcgc aaggcttgtt ctatctcaga ccaagctttc cgcgatgcgc ttgactttat
    34021 caaaccagga aaaactgaaa ttgagattgc caacttcctt gatttccgca tgcgtgagtt
    34081 gggagcatct ggcttatctt ttgatacgat cctagctagc ggtatcaatt cttctaaacc
    34141 ccatgcccat ccaatgcaca aaccagtgga gttgggagaa gccatcacca tggacttcgg
    34201 ctgtctctat gaccactatg tcagtgatat gacccggact atctatctag ggcatgttag
    34261 cgatgagcag gcagagattt acaatacggt tctaaaagct aaccaagcct tgattgacca
    34321 agctaaggca ggcttaggtt tccgtgactt tgacaaaatc cctcgtgata ttatcattga
    34381 ggcaggttat ggtgactact ttactcacgg cattggccac ggtattggtc tggatatcca
    34441 tgaggaaccc tactttagtc agacttctac agaaactatt aagacaggta tggccttgac
    34501 cgatgaacca ggtatctata tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct
    34561 gattacagag acaggttgtg aattattgac cctagctcca aaagagttga tagtcattta
    34621 gttgtttgtc aagaaaaaag tacgaaaatg acgaaaaaag tcaaaaaaaa ttaaaaatag
    34681 gtcgcaagtc ggatgttttt tatggtataa tagactaaac tgatagtaac atgtagcgaa
    34741 aggggtaggt acatgattaa aatttataca gtctcaagtt gtactagctg taaaaaagca
    34801 aaaacctggc tcaatgccca ccagttaagt tataaagaac aaaaccttgg taaagaagga
    34861 attacgagag aagaattact ggatattcta accaaaacag ataacggaat agccagcatc
    34921 gtttcgtcta aaaatcgcta tgccaaagcc cttggagtgg atattgaaga tttgagtgtc
    34981 aatgaagttc tcaatctgat tatggaaaca ccgagaattt taaagagccc aatccttgta
    35041 gatgaaaaac gcctgcaagt tggctacaag gaagacgata ttcgtgcctt cctaccacgc
    35101 tctgtccgta atgtagaaaa tgcagaagca cgtttgcgtg cagctctata aacatcaagg
    35161 ctgggagcac ttcccagtct tattctattt taatttcaaa aagaaagaag aaagaaatga
    35221 aaaaaatagt tcttgttagt ctagctttcc tttttgtcct ggttggttgc ggacagaaaa
    35281 aagaaactgg accagctaca aaaacagaaa aagatacgct tcagtcggca ttgccagtta
    35341 ttgaaaatgc tgagaagaat acagttgtaa ctaagacttt ggtcttgccc aagtcagatg
    35401 atggtagcca gcagacacaa acaattactt acaaagacaa gacttttttg agtctagcta
    35461 tccaacaaaa acgtccagtc tctgatgagt tgaagactta tattgaccaa catggagtgg
    35521 aggaaactca aaaagctctt cttgaagcgg aggagaagga taagtctatc attgaagctc
    35581 gtaaattggc aggtttcaaa cttgaaacaa aactattgag cgcaacggaa cttcaaacaa
    35641 cgactagttt tgattttcaa gttctggatg tcaagaaggc ttcccagttg gaacatctga
    35701 agaatattgg tttggaaaat cttttgaaaa atgaaccaag caaatatatt tcagatagat
    35761 tggcaaatgg cgcgacagaa caatagaaaa tccaaataaa tagactgcct gaattgtaga
    35821 aggtaaggaa ttatgctata atggtactat tctaaggaaa gagggtgtta gaatgggatt
    35881 tactgaagaa acagtacgtt ttaaattgga cgattccaat aaaaaagaaa ttagcgaaac
    35941 tttgacagat gtttatgctt cgttgaacga taagggttac aacccaatta accaaatcgt
    36001 aggttacgta ttgagtggag accctgccta cgttcctcgt tataataatg cacgaaatca
    36061 aatccgtaag tatgagcgtg atgaaatcgt tgaggaattg gttcgctact acctcaaagg
    36121 acaaggagtc gatctataac ctatgagaat tatgggattg gacgtcggtt caaaaacggt
    36181 aggggtggcg attagcgatc cgcttggttt tacagctcaa gggcttgaaa tcatccagat
    36241 aaatgaagaa caaggccaat ttggttttga ccgcgttaag gaattggttg atacttacaa
    36301 ggtggaacga tttgtagtgg gcttgcctaa aaacatgaac aatacaagtg gaccgcgcgt
    36361 agaagctagt caagcctacg gagcaaagct agaagagttt tttggtttac cagtagacta
    36421 tcaggatgaa cgcttgacaa cagtggctgc tgagcgcatg ttgattgaac aagcagatat
    36481 cagtcgcaat aagcgcaaga aagtcattga taagttagca gctcagctga ttttacaaaa
    36541 ttatttagat agaaaatttt aatataaagg agaggctatg tcacacgatc ataaccacga
    36601 ccacgaagaa cgtgaactaa tcacactagt agatgagcaa ggaaatgaaa ccttgtttga
    36661 aatccttttg acaattgatg gaaaagaaga atttggtaaa aactatgttc ttctagtacc
    36721 agttaacgca gaagaagacg aagacggaca agttgaaatc caagcttact cattcattga
    36781 aaatgaagat ggaacagaag gcgaattgca accaatccca gaagactcag aagacgaatg
    36841 gaacatgatt gaagaagtct tcaacagctt tatggaggag tgatacagtc tgggagactg
    36901 tatcagccca actcccagaa atggggaaga gttggaacgt ccagtgaaca tttttacccc
    36961 atattcacat tcatagtggc tagttattag ctaatcaggt aagaggtcgg gacgaaaatc
    37021 ctggccttgt ttttattagt aaccatactt taatgcgata attgattgga cttttgtcaa
    37081 ggagatgtgt atgtttgaag tagaagaatg gctccatagt cggattggtt tgaattttcg
    37141 atcaggtttg ggccgaatgc agcaagcggt ggatttgtta ggaaatcctg agcagtctta
    37201 ccctattatc cacgtaacag ggactaatgg gaaaggatct accattgctt ttatgaggga
    37261 attatttatg gggcatggca aaaaagttgc gacctttacc tcccctcata tcgtctctat
    37321 caatgaccga atctgcatta atgggcaacc tatagcagac gcagacttta tccgtttgac
    37381 tgatcaggtc aaggagatgg agaaaacgct tctgcaaact cctgcccagt tgtccttttt
    37441 tgaattgctg accttagttg cttttcttta ttttagggag caagaggtgg atttggtttt
    37501 attagaagtg ggaattggtg gcttacttga cacgaccaat gtggtaactg gagagcttgc
    37561 tgtcatcacc tccattgggc ttgaccatca agaaaccttg ggtgatagtc tagaagcaat
    37621 tgcagagcag aaagctggta ttttcaaggc tggtaagaag gcagtgattg cgaaattgcc
    37681 tccagaagct aggcttgtct gtcagaaaaa agccgaatct ttagctgtta acctttatca
    37741 ggcaggtcaa gattttttaa tgctgaatgg tgatttttca agctctttac taaatctttc
    37801 acagctgaac ataggcttag aaggagtcta tcagcaggag aatgcagcct tggcgttgca
    37861 aacttttctt ctttttatgg gagaaggaaa ggaagctgtt gatgaacagg ctgtaagaaa
    37921 ggccttggaa cagacccatt gggctggtcg cttggagcgt attcgcccac agatttactt
    37981 ggatggtgct cataacctcc ctgccttgac tcgcttggtt gagtttatca aagaaaaaga
    38041 gcaggaaggc tatcgacctc aaatcctctt tggatccttg aaacgtaagg attatcaagg
    38101 gatgttgggt tatctgactg aaaatttacc tcaagtggaa ctcaagatga ctggctttga
    38161 ctatcaaggg tctttggacg agacagatgt aacaggttac catgtaattc cctcttaccg
    38221 agaatttatc agcagtttcg aagaaagggc agacgctcaa gacttgctgt tcgttacagg
    38281 gtctctctat tttatctcag aagtacgggg ctacctgctg gaccgtgagc agataaattg
    38341 actccatttt ttgaacttgt tatactaggg gaattgctgg ttagagaaaa tttctctaaa
    38401 ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat tcacactttc tcttgcttct
    38461 ctagcaagtt ttagtctctt agtagcttgt tcacaaagag ctcaacaggt tcaacagcct
    38521 gttgctcagc agcaggtcca acaacctgct caacagaata ccaatactgc aaatgcagga
    38581 ggtaaccaaa atcaagcggc tccagtacaa aaccaacctg ttgctcaacc gaccgatatt
    38641 gatgggactt atactggtca ggatgacgga gaccgtatca ctttagtggt aactggaacg
    38701 actggtacat ggactgagct cgaatctgac ggggatcaga aagtcaaaca ggttacattg
    38761 gattcagcaa atcaacgcat gattattggc gatgatgtca aaatttacac tgtaaacggt
    38821 aatcaaatcg tcgtagatga tatggataga gacccatcgg accaaatcgt tttaactaaa
    38881 taagactatg caagtagaaa gggctggatt tttcagcctt tttactttta cctagaaaat
    38941 aatcataaat acttgccttc taccgaatac ctgcgttata ctagtatcaa ttacttgttt
    39001 ttagcattca aactatcaag gaggggatat gaaatatagg aaatttcagt tattgatgtc
    39061 caagtatggc tttagtcttt cgattatgct acttgaactt tgtcttgttt ttggtctctt
    39121 tctttattta ggacgcatgg ctcccatttt atggattact gtcctcattc tactgagtat
    39181 catcacaatc atttcgatag tcaaccgtaa tacgactcct gagaataagg taacctggtt
    39241 gttagtagcc tttgtaccag tatttggtcc cttgctctat ctgatgtttg gtgaaaggcg
    39301 attgtccaaa aaagaaatca aacaactgaa gaagctaggc tctatgcatt tccaagaagc
    39361 aaatagccag ctactaaaag agaaattaaa agaaagtgac aaggcagctt atggagtcat
    39421 caagtcctta ttgagtatgg ataccaatgc tgacatctat gatcaaactg cctctacatt
    39481 ttttcctaac ggagaagcta tgtggaaaaa gatggtagaa gatcttaaaa aggctgagaa
    39541 atttattttc ttggaatatt acattataga agaaggtttg atgtggaatc gcatactaga
    39601 tatactagag caaaaggtag ctcagggtgt agaggttaag atgctctatg atgatatcgg
    39661 ctgtatggct actttaacag gagattatgc acatcgactt cgtcagctgg gcatcgaggc
    39721 ccataaattc aataaagtta ttcctcgttt gacagtggct tataataaca gagatcatag
    39781 aaaaatattg attgttgatg gtcagatagc ctatactggt ggggtcaatc tggcagatga
    39841 gtacattaac cacgtcgaga gatttggtta ttggaaggat agtggaattc gcttagacgg
    39901 actagcagta aaagccctga cacgcttatt tttgaccact tggtacatta atcgaggaga
    39961 aattagtgat tttgatcaat atcatttaga aaatcattct atcccgagtg acggtttaac
    40021 cattccatac ggaagtggac ccaagccaat ttttcgagcg caggtaggga aaaaagttta
    40081 tcagagttta atcaatcaag caacggaatc ggtctatatt acgacacctt atttgattat
    40141 agattatgat ttaacagaga caatcaaaaa tgcagctatg agaggggtcg atgttcgaat
    40201 tatcacccct tacataccag ataagaagtt cattcagtta gtcacgagag gagcttatcc
    40261 cgaccttctt tctgctggtg ttcggattta tgagtatagt ccaggtttta ttcatagtaa
    40321 gcagatgttg gtagacgaag attttgcggt ggtggggaca atcaatctcg actaccggag
    40381 cttggtacac cattatgaaa atgcagtctt actctataaa actccttcta taagggaaat
    40441 cgcccgagat tttcgaaata tatttgcaga ttctcaggaa gtctatcctc attctatcaa
    40501 aacgagctgg tatcaaaagc ttgtaaaaga aatcgcccag ctattcgccc ctatcttata
    40561 agaaatctag aacttaggat acaaaccaga cctatttttc ttgtctttta cgaatagaaa
    40621 gaaagaggag gggaattcat gctaactaag gaagaagtga atgatatgat tgagttcaaa
    40681 cagacacatt tacaccgctt tcgggaaatt gaaacctttg tgaaactatg caaaaaatca
    40741 ctcaaacagc catcgcaagc tgacaatcct aggacttttt gatatactaa gacagataaa
    40801 ttgaacagga gaaacgatat gagtgtgtat ggtagagtag aagaagttca taaggagaat
    40861 cgtgaacctc tagaatacca aatcgaacaa gaatcgcatc atcgtgaatc aagtcgtctt
    40921 cctttggtga aaattttact atggagtacg cttgtaacgg ggataactct aggagtaccg
    40981 ctattactcg acttaatgag tgcacaagaa gtgcaggatt tttatgcagg ttgggcgctt
    41041 catcagacag ggaagattta cagcgactat tatggaagtc aaggtttgct ttattatttg
    41101 ctgacttacg tgagtcaggg cggatttttc tttgccatct ttgagtggtt agccttggta
    41161 gcaggaggat ttttcctttt tagatcagcg gacaccttga cagagcaagg agaccaagct
    41221 ggacatctgg tgactatttt ttacatgcta gttacaggtc ttgcttttgg tggaggctat
    41281 gcgactcttt tagcgcttcc tttcttattc gcagccttta gtttagttgc ggcttaccta
    41341 agcaatccaa gccatgataa gggatttgta cggattgggc tagctttggc aggcggattt
    41401 ttctttgctc ccttatcatc gctcctgttt attgctgtag tgagtttagg cttgttggtc
    41461 tttaaccttg ggcatagacg ctttgcgcat gggttttatc agtttcttgc agtggcttta
    41521 ggtttttcac ttgtctttta tccaactgcc tactatagtg ctgcaacagg aagttttggg
    41581 gatgcgatta gtggtattcg ttatcctatt gacagtattc gctttgattt tacttctaaa
    41641 attttagaga atatgttttt ttatggcttg ttgtcccttg gtttgggatt tgtggtttgt
    41701 atctttttag gtctctttca atccaaaccc tttaaactat acgtcatttc ggttcctgca
    41761 agtcttgtgg taattttagg tttgatttta cttttctttt cacaagagcc tctgcacgct
    41821 tcttatttga tggtcgtctt ccctgttttc ctacttttat tggtaaccaa tattaagagt
    41881 caacagaggg ggcgtagtgc tagaagaagc cgaagagaaa cgccagttag cctatggagt
    41941 cgtttcttca aaggaaatct atatctgcta gtttttgggt ttgtctatct tttgtctgtt
    42001 ccttttttga tgaagtttgt cctttatcca gtaccttatc aagaacgtaa tcgtcttgct
    42061 gatttggtaa aagaggagac aaatacggaa gatgctatct atgcatggga tgatactgcg
    42121 actctttatc gtaagagtga gcgcttgtcg ccatcggcga ttttgtcccc gttgcactat
    42181 acagcaactg aggaaaatcg taataagtta cttaatgact tgaaagaaaa acaacctaag
    42241 gtgattgtgg taaatgacaa ggtggtagtc tggtctgaag tggaaacact cttaaaagaa
    42301 aattaccaac aagtaaagac tgattactca gagtttaaag tctataaaat taaataacca
    42361 aatcaatatc ttgtgtattt ttaaaaattt taggattttt aacacaagat attgattttt
    42421 ctttttagag tggtataata ctttttagaa agaacatttt agaaaagagc atgcatatga
    42481 ttgcactaga agaaaaaatt acaattttgc caactctctt cgtcgagaaa cgagatggga
    42541 gacgtgttgt atttgatgtg gacaagattg acaaggctct ccacaaggcg gctgacaagg
    42601 ttatggatgt gacacccctg gttgaaaaac gcctcaatga tctgactgag cgaattatta
    42661 cagaaattca tagtcgcttt ccacagggaa ttaagattta cgaaattcaa aatatcgtag
    42721 aacatgaact ccttgaagcc aaagaatatg cgctggctga ggagtatatt acttatcgga
    42781 cacagaggga ttttgagcgc tcaaaagcga cggatatcaa ctttagtatt cataaacttc
    42841 tcaacaaaga ccagacagtt gtcaatgaaa atgctaataa agacagtgat gtctttaaca
    42901 ctcagcgtga tttgacagca gggattgttg ggaaatcaat cggactgcaa atgcttccta
    42961 agcacgtagc caatgcccac caaaaggggg atatccacta tcacgatttg gactacagtc
    43021 cctatacccc tatgaccaac tgctgtttga ttgattttaa gggtatgttg gaaaatggtt
    43081 ttaagattgg aaatgcagag gtagagagtc ccaagtctat ccagactgcg acagcacaga
    43141 tttctcaaat cattgccaac gttgcttcta gccagtacgg tggctgttca gctgaccgta
    43201 tcgatgaaat tttggcgcct tatgcagaga agaactatca aaaacatctc aaagatgcag
    43261 aagagtgggt attgcctgaa aaacgggaag attacgcttg gaagaaaacg caaaaggaca
    43321 tctacgatgc catgcaatct cttgagtatg aaatcaatac tctctttact tcaaatggac
    43381 aaacaccttt tacttcgcta ggttttggtc tgggaaccag tcgttttgaa cgagaaattc
    43441 aaaaagctat tttaaacatt cgcatcaagg gtcttggttc agaacaccgt acggctatct
    43501 ttcctaaact tatctttacg cttaaaagag gcctcaactt agaggaagga actcccaact
    43561 atgacatcaa gcagttggct ctagagtgtg caaccaagcg gatgtatcca gacgtcttgt
    43621 cttatgataa gattgttgat ttgacaggtt ctttcaaggt gcctatgggc tgccgttctt
    43681 tccttcaagg gtggaaggat gaaaatggtg tagaagtcaa ttcaggtcgc atgaatctgg
    43741 gtgttgtgac ggttaatctg cctcgtattg ctcttgagtc tgaaggtgat atgaataagt
    43801 tctgggaaat cttcaacgag cgaatgaata tcgcagaaga tgctcttgtt taccgtgtcg
    43861 aacgcactaa agaggcgaca ccagcgaatg ctcctattct ttatcagtac ggtgcttttg
    43921 gccatcgtct aggtaaagaa gaaagtgttg accagctctt taagaatcgt cgtgcgaccg
    43981 tttcgctggg ctatatcggc ttgtatgaag tagcgacagt tttctttggt aacagctggg
    44041 aaagtaatcc agatgctaag gaattcacgc tagacatcat tcacgatatg aaacgccgtg
    44101 tagaagagtg gtcagaccaa tatggctacc atttctctat ctactcaaca ccatccgaaa
    44161 gtctgacaga ccgtttctgc cgactagata tagacaagtt tggctctatt cctgatatca
    44221 cagacaagga atactacacc aactctttcc actacgatgt tcgtaaaaat ccaacaccgt
    44281 ttgaaaaatt ggactttgag aaagtctatc cagaagcagg tgcgtcaggt ggtttcatcc
    44341 attattgtga gtatccagtc cttcagcaaa atccaaaggc cttggaagct gtctgggatt
    44401 atgcttatga ccgtgtaggc tatctaggca ccaatactcc gattgaccgt tgctacaagt
    44461 gtgactttga aggggatttt gaaccaactg agagagggtt tgcttgtcca aactgtggca
    44521 atagcgatcc taaaacagta gacgttgtta aacggacttg tggctatctt ggcaatcctc
    44581 aagcgagacc aatggttaac gggcgtcaca aggaaatcgc tgcgcgtgtc aaacatatga
    44641 atggttcaac gattaaaata gctgggcatc aagtaacaaa ttagaaagaa atgaaatggg
    44701 aaaatatcaa ctagacgata aggggcgcgc acaagtgacc cgttatcacg agaaacactc
    44761 taaaggtgga gctggtaaga aagaacgctt gcttagcttc agagaacaat ttttaaacaa
    44821 gaacaagaaa aaataaaagt gagagccagc tctcgctttt ctcatagtgg gaggtaggga
    44881 tggaattacg cagaccaaga ttagcggata agaaagctgt tttagatatg atgacagagt
    44941 ttgaaaagag ccaatcagcc catgatggag gattttggga tgttgaggat ttttcttacg
    45001 aggagtggct agaaggtaac cgtaataaag aaatgggaat atggctacct gaaaatcgcg
    45061 ttccatcgat acagttcgta ttgtttggtg aatcaggttg tgctctagga tttttgaatc
    45121 tgcgattgag actgaatgag gggttactga attatgctgg ccacattggc tactccattc
    45181 gtccatctga aagaggcaag ggttatgcaa aagagactct ccgtcagggc ttgcaagttg
    45241 ctaaggaaaa gaacatcaag aaagctctgg tgacctgtag cgtgaataat cctgctagca
    45301 gagcagtcat tctagcaaat ggtggaatat ttgaggatgc tcgcaatgga gtcgagcgtt
    45361 attggataga ggtagcgaat gaataatcca aaaccacaag aatggaaaag cgaggaactt
    45421 agtcaaggtc gtatcattga ctacaaggcc tttaactttg tggacggaga aggcgtgcgc
    45481 aactctctct atgtagcagg ttgcatgttt cactgcgagg ggtgttataa tgtagcgacc
    45541 tggtccttca atgcaggcat tccctataca gctgagttgg aagaacagat tatggcagat
    45601 cttgcccagc cttatgttca ggggttaacc ttactaggag gggagccttt tcttaatact
    45661 gggattctct tgccacttgt taagcggatt cggaaggaat tgccagacaa ggacatctgg
    45721 tcctggacgg gctacacttg ggaagaaatg atgttggaaa ctccagataa actggaactc
    45781 ttgtcactga ttgacattct tgtcgatgga agatatgatc gaactaagag aaatcttatg
    45841 ctccagtttc gaggttcgtc caaccaacga attatcgatg tgcaaaaatc gctcaaaagt
    45901 gggcaagtag tgatttggga caagctcaat gacggaaaag aaagctatga acaggtgaag
    45961 agagaatgaa gaaaaaagac ttagtagacc aactagtctc agagatcgag acggggaaag
    46021 tcaggacact gggaatatac ggtcatggag cttcaggtaa atcaaccttt gcacaggaat
    46081 tgtaccaagc tttagattct actacagtaa atttgctaga gacagatcct tatatcacct
    46141 caggacgcca tctggtagta cccaaggacg cgccgaatca aaaggtgaca gccagtctgc
    46201 cagtggcgca tgaactggag agtttgcaga gagatatcct tgccttgcag gcgggtatgg
    46261 atgtcttgac aattgaagaa ccttggaagg ctagtgaggt cttgtctgga gccaaaccaa
    46321 ttttgattgt cgaagggatg tctgttggct ttctacccaa ggaactcttt gaaaaaacca
    46381 tctgtttcta cacggatgag gagaccgaat taaagcgacg ccttgctaga gatacgactg
    46441 tgagaaatcg cgatgcatcc tttatattgg ctagccatca gatgagacgg gagcagtatc
    46501 tgcgatacta taaagaaact gagtctaagg cggatatctt agtggaccaa tcagaagata
    46561 aatttgatgt caagaggact taacttatgt atagaatgta tagaagaaat atagaagaaa
    46621 atccctaatt ttagaaagaa aaagtaggaa aacagtttca tcccaaaaaa acgaaaaaac
    46681 agcaacaaat cccttgcaat cgcaggggct ttgtgttatt ctattatggt gctgtaaatt
    46741 acagccttag ttttgatgca agaggttgcg acacgctcgg ttgcattgcc acgcaacacc
    46801 gcgtcggttt tcttgtggag ctagcctatt atcttaaata gacgaaaagg agaaaaagat
    46861 ggcaaacaaa aaaatccgta tccgtttgaa agcttacgaa caccgtacgc ttgacacagc
    46921 ggctgcaaaa atcgtagaat cagctactcg tacaggtgca caagttgcgg gtccaatccc
    46981 acttccaact gaacgtagcc tctacacaat cattcgtgcg actcacaaat acaaagactc
    47041 tcgcgaacaa tttgaaatgc gtacacacaa acgtttgatc gatatcgtta acccaactca
    47101 aaaaacagtt gatgccttga tgaaattgga tcttccaagt ggtgtaaacg tagaaatcaa
    47161 actttaatct aaaatataaa agagcagagg ctggtgtttc aatctaattg aacacgggct
    47221 aaactcggtg tgaaaaagat aaacttccta gtgtctgcta gacactgcgt cagtttccta
    47281 ttttgacgtt gagtttgacg tcctttgtat cttagacttg agcataaaaa acgctcgtta
    47341 aaaacttttt gaataaaaaa tatagaaaag gaactatttt ctcatgacaa aaggaatctt
    47401 agggaaaaaa gtgggaatga ctcaaatctt cactgaagct ggcgaattga tccctgtaac
    47461 agttattgaa gcaactccaa acgttgttct tcaagttaaa actgttgaaa cagacggata
    47521 caacgctatc caagttggtt tcgatgacaa acgcgaagta ttgagcaaca aacctgctaa
    47581 aggacatgta gcgaaagcta acacggctcc taagcgcttc attcgtgaat tcaaaaacgt
    47641 tgaaggcttg gaagttggcg ctgaaatcac agttgaaaca ttcgcagctg gagatgttgt
    47701 tgacgtaacg ggtacttcta aaggtaaagg tttccaaggt gttatcaaac gccacggaca
    47761 atcacgtgga ccaatggctc acggttctcg ttaccaccgt cgtccaggtt ctatggggcc
    47821 tgttgcacct aaccgcgtat tcaaaggtaa aaaccttgca ggacgtatgg gtggcgaccg
    47881 cgtaacaatt caaaaccttg aagttgtaca agttgttcca gaaaagaacg ttatccttat
    47941 caaaggtaac gtaccaggtg ctaagaaatc tcttatcact atcaaatcag cagttaaagc
    48001 tggtaaataa taaagaaagg ggaaatcagt cacaatggca aacgtaacat tatttgacca
    48061 aactggtaaa gaagctggcc aagttgttct tagcgatgca gtatttggta tcgaaccaaa
    48121 tgaatcagtt gtgtttgatg taatcatcag ccaacgcgca agccttcgtc aaggaacaca
    48181 cgctgttaaa aaccgctctg cagtatcagg tggtggacgc aaaccatggc gtcaaaaagg
    48241 aactggacgt gctcgtcaag gttctatccg ctcaccacaa tggcgtggtg gtggtgttgt
    48301 cttcggacca actccacgtt catacggcta caaacttcca caaaaagttc gtcgcctagc
    48361 tcttaaatca gtttactctg aaaaagttgc tgaaaacaaa ttcgtagctg tagacgctct
    48421 ttcatttaca gctccaaaaa ctgctgaatt tgcaaaagtt cttgcagcat tgagcatcga
    48481 ttctaaagtt cttgttatcc ttgaagaagg aaatgaattc gcagctcttt cagctcgtaa
    48541 ccttccaaac gtgaaagttg caactgctac aactgcaagt gttcttgaca tcgcaaatag
    48601 cgacaaactt cttgtcacac aagcagctat ctctaaaatc gaggaggttc ttgcataatg
    48661 aatttgtatg atgttatcaa aaaacctgtc atcactgaaa gctcaatggc tcaacttgaa
    48721 gcaggaaaat atgtatttga agttgacact cgtgcacaca aacttttgat caagcaagct
    48781 gttgaagctg ctttcgaagg tgttaaagtt gccaatgtta acacaatcaa cgtaaaacca
    48841 aaagctaaac gtgttggacg ttacactggt tttactaaca aaactaaaaa agctatcatc
    48901 acacttacag ctgattcaaa agcaatcgag ttgtttgctg ctgaagctga ataatctaag
    48961 gaggaaatat cgtgggaatt cgtgtttata aaccaacaac aaacggtcgc cgtaatatga
    49021 cttctttgga tttcgctgaa atcacaacaa gcactcctga aaaatcattg cttgttgcat
    49081 tgaagagcaa ggctggtcgt aacaacaacg gtcgtatcac agttcgtcac caaggtggtg
    49141 gacacaaacg tttctaccgt ttggttgact tcaaacgtaa caaagacaac gttgaagcag
    49201 ttgttaaaac aatcgagtac gatccaaacc gttctgcaaa catcgctctt gtacactaca
    49261 ctgatggtgt gaaagcatac atcatcgctc caaaaggtct tgaagtaggt caacgtatcg
    49321 tttcaggtcc agaagcagat atcaaagtcg gaaacgctct tccacttgct aacatcccag
    49381 ttggtacttt gattcacaac atcgagttga aaccaggtcg tggtggtgaa ttggtacgtg
    49441 ctgctggtgc ctctgctcaa gtattgggtt ctgaaggtaa atacgttctt gttcgtcttc
    49501 aatcaggtga agttcgtatg attcttggaa cttgccgtgc tacagttggt gttgtcggaa
    49561 acgaacaaca tggacttgta aaccttggta aagcaggacg tagccgttgg aaaggtatcc
    49621 gcccaacagt tcgtggttct gtaatgaacc ctaacgatca cccacacggt ggtggtgaag
    49681 gtaaagcacc agttggtcgt aaagcaccat ctactccatg gggcaaacct gctcttggtc
    49741 ttaaaactcg taacaagaaa gcgaaatctg acaaacttat cgttcgtcgt cgcaacgaga
    49801 aataatatta aactagtcgc ttaagcaact agtaaatccg ccagctcggt agtgctccat
    49861 aggagcgcaa gccgctgtgg tacaacattt aaaggagaaa atataaaaat gggacgcagt
    49921 cttaaaaaag gacctttcgt cgatgagcat ttgatgaaaa aagttgaagc tcaagctaac
    49981 gacgaaaaga aaaaagttat taaaacttgg tcacgtcgtt caacgatctt cccaagtttc
    50041 attggttaca ctattgcagt ttatgacgga cgtaaacacg tacctgttta catccaagaa
    50101 gacatggtag gccacaaact tggtgaattt gcaccaactc gtacttacaa aggtcacgct
    50161 gcagacgaca agaaaacacg tagaaaataa ggagaacata aatggcagaa attacttcag
    50221 ctaaagcaat ggctcgtaca gtacgtgttt cacctcgtaa atcacgtctt gttcttgata
    50281 acatccgtgg taaaagcgta gccgatgcaa tcgcaatctt gacattcact ccaaacaaag
    50341 ctgctgaaat catcttgaaa gttttgaact cagctgtagc taacgctgaa aacaactttg
    50401 gtttggataa agctaacttg gtagtatctg aagcattcgc aaacgaagga ccaactatga
    50461 aacgtttccg tccacgtgcg aaaggttcag cttcaccaat caacaaacgt acagctcaca
    50521 tcactgtagc tgttgcagaa aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa
    50581 ttggtatgcg tgtcggcatc atccgtgatt gggatgccaa atggtatgct gaaaaagaat
    50641 acgcggatta ccttcatgaa gatcttgcaa tccgtaaatt cgttcaaaaa gaacttgctg
    50701 acgcagcagt ttcaactatt gaaatcgaac gcgcagtaaa caaagttaac gtttcacttc
    50761 acactgctaa accaggtatg gttatcggta aaggtggtgc taacgttgat gcactacgtg
    50821 caaaacttaa caaattgact ggaaaacaag tacacatcaa catcatcgaa atcaaacaac
    50881 ctgatttgga tgctcacctt gtaggtgaag gaattgctcg tcaattggag caacgtgttg
    50941 ctttccgtcg tgcacaaaaa caagcaatcc aacgtgcaat gcgtgctgga gctaaaggaa
    51001 tcaaaactca agtatcaggt cgtttgaacg gtgcagatat cgcccgtgct gaaggatact
    51061 ctgaaggaac tgttccgctt cacacacttc gtgcagatat cgattacgct tgggaagaag
    51121 cagatactac atacggtaaa cttggtgtta aagtatggat ctaccgtggt gaagttcttc
    51181 cagctcgtaa aaacactaaa ggaggtaaat aaccaatgtt agtacctaaa cgtgttaaac
    51241 accgtcgtga attccgtgga aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtagcat
    51301 tcggtgaata cggtcttcaa gctacaacta gccactggat cactaaccgc caaatcgaag
    51361 ctgctcgtat cgccatgact cgttacatga aacgtggtgg taaagtttgg attaaaatct
    51421 tcccacacaa atcatacact gctaaagcta tcggtgtgcg tatgggatct ggtaaagggg
    51481 cacctgaagg ttgggtagca ccagttaaac gtggtaaagt gatgttcgaa atcgctggtg
    51541 tatctgaaga gattgcacgt gaagcgcttc gacttgctag ccacaaattg ccagttaaat
    51601 gtaaattcgt aaaacgtgaa gcagaataag gagaaggcat gaaacttaat gaagtaaaag
    51661 aatttgttaa agaacttcgt ggtctttctc aagaagaact cgcgaagcgc gaaaacgaat
    51721 tgaaaaaaga attgtttgaa cttcgtttcc aagctgctac tggtcaattg gaacaaacag
    51781 ctcgcttgaa agaagttaaa aaacaaatcg ctcgtatcaa aacagttcaa tctgaagcga
    51841 aataatagac tagggaagga gaaatttcaa tggaacgcaa taatcgtaaa gttcttgttg
    51901 gacgtgttgt atctgacaaa atggacaaga caatcacagt tgtagttgaa acaaaacgta
    51961 accacccagt ctatggtaaa cgtattaact actctaaaaa atacaaagct catgatgaaa
    52021 acaatgttgc caaagaaggt gatatcgtac gtatcatgga aactcgcccg ctttcagcta
    52081 caaaacgttt ccgtcttgta gaagttgttg aagaagcggt catcatctaa tcaaacctga
    52141 aaggagaaaa ctgaaatgat tcaaacagaa actcgtttga aagtcgcaga caacagcggt
    52201 gctcgcgaaa tcttgactat caaagttctt ggtggttcag gacgtaaatt tgcaaacatc
    52261 ggtgatgtta tcgtggcatc tgtaaaacaa gctactcctg gtggtgcggt taaaaaaggt
    52321 gacgttgtta aagcagttat cgttcgtact aaatcaggtg ctcgtcgtgc tgatggttca
    52381 tacatcaaat ttgacgaaaa cgcagcagtt atcatccgtg aagacaaaac tcctcgcgga
    52441 acacgtatct ttggcccagt tgcacgtgaa ttgcgtgaag gtggtttcat gaagatcgtg
    52501 tcacttgctc cagaagtact ttaattttta ggaacaaact agtcccctag cttcaagcta
    52561 gggtgccctt atgggcgtaa gaaaaatcaa ggagaaacct aatgtttgta aaaaaaggcg
    52621 acaaagttcg cgtaatcgct ggtaaagata agggaacaga agctgttgtc cttactgccc
    52681 ttccaaaagt aaacaaagtt atcgttgaag gtgttaacat tgttaagaaa caccaacgtc
    52741 caactaacga gcttcctcaa ggtggtatca tcgagaaaga agcagctatc cacgtatcaa
    52801 atgttcaagt tttggacaaa aatggtgtag ctggtcgtgt tggttacaaa tttgtagacg
    52861 gtaaaaaagt tcgctacaac aaaaaatcag gcgaagtgct tgattaatca cgaaggaaag
    52921 gagaagtata atggcaaatc gtttaaaaga aaaatatctt aatgaagtag ttcctgcttt
    52981 gacagaacaa ttcaactact catcagtgat ggctgtgcct aaagtagata agattgtttt
    53041 gaacatgggt gttggtgaag ctgtatcaaa cgctaaaagc cttgaaaaag ctgctgaaga
    53101 attggcactt atctcaggtc aaaaaccact tatcactaaa gctaaaaaat caatcgccgg
    53161 cttccgtctt cgtgaaggtg ttgcgatcgg tgcaaaagtt acccttcgtg gtgaacgtat
    53221 gtacgaattc ttggataaat tggtatcagt ttcacttcca cgtgtacgtg acttccacgg
    53281 tgtcccaaca aaatcatttg atggacgcgg gaactacaca cttggtgtga aagaacaatt
    53341 aatcttccca gaaatcaact tcgatgacgt tgacaaaact cgtggtcttg acatcgttat
    53401 cgtaacaact gctaacactg acgaagagtc acgtgcattg cttacaggcc ttggaatgcc
    53461 ttttgcaaaa taatatagga ggtaaatcta atggctaaaa aatcaatggt agctagagag
    53521 gctaaacgcc aaaaaattgt tgaccgttat gctgaaaaac gtgctgcatt aaaggcggca
    53581 ggggactacg aaggtttatc taaattacct cgcaacgcct caccgactcg tttacataat
    53641 cgttgtagag ttacggggcg cccacattca gtttaccgca aatttggtct gagtcgtatc
    53701 gcttttcgcg aacttgcgca taaaggtcaa attcctggtg taacaaaagc atcttggtaa
    53761 tttaagatat caagggtgtc aaaactccaa gtaaaaatag gaaacttgac gaagaaacta
    53821 aagtttctag gaaagtttat ctttttcaca cagagtttag cccgggttca attgggcttg
    53881 ccaatttgaa cccgagctac agctttggca aaaaagacca atttgctttg gagcattgct
    53941 tctgcattaa attgtctatt tttgctcgtg ctgttacgct ctttgtatca tgtattaact
    54001 agcaagtgca acttgcaaac tactagtaag aggagaaaaa caaaatggtt atgactgacc
    54061 caatcgcaga cttcctaact cgtattcgta atgctaacca agctaaacac gaagtacttg
    54121 aagtacctgc atcaaacatc aaaaaaggga ttgctgaaat ccttaaacgc gaaggttttg
    54181 taaaaaacgt tgaaatcatc gaagatgaca aacaaggcgt catccgtgta tttcttaaat
    54241 acggaccaaa tggtgaaaaa gttatcacta acttgaaacg tgtttctaaa ccaggacttc
    54301 gtgtctacaa aaaacgtgaa gaccttccaa aagttcttaa cggacttgga attgccatcc
    54361 tttcaacttc tgaaggtttg cttactgata aagaagcacg ccaaaagaat gttggtggtg
    54421 aggttatcgc ttacgtttgg taaaatcaag atacaaagct cgtaaagaac aaagcaaaat
    54481 taggaagttg gagaagtttg tttacaaaca agccaactta tctattttgc acagttctta
    54541 gagcgtgttc agttcagctc ttgaactaaa taagtatctg aaccccgtga aaactggccg
    54601 ttctggcctg acaatttaac aggagaaaat aaacatgtca cgtattggta ataaagttat
    54661 cgtgttgcct gctggtgttg aactcgctaa caatgacaac gttgtaactg taaaaggacc
    54721 taaaggagaa cttactcgtg agttctcaaa agatattgaa atccgtgtgg aaggtactga
    54781 agtaactctt caccgtccaa acgattcaaa agaaatgaaa actatccacg gaactactcg
    54841 tgcccttttg aacaacatgg ttgttggtgt atcagaagga ttcaagaaag aacttgaaat
    54901 gcgtggggtt ggttaccgtg cacagcttca aggatctaaa cttgttttgg ctgttggtaa
    54961 atctcatcca gacgaagttg aagctccaga aggaattact tttgaacttc caaacccaac
    55021 aacaatcgtt gttagcggaa tttcaaaaga agtagttggt caaacagctg cttacgtacg
    55081 tagccttcgt tcaccagaac catataaagg taaaggtatc cgttacattg gtgaattcgt
    55141 tcgccgtaaa gaaggtaaaa caggtaaata atgttgagtg gttgatcatc aaccaccaac
    55201 ctattttcca actttgtgca tagcacacga tttaaaacta aagaggtgaa aactgtgatt
    55261 tcaaaaccag ataaaaacaa actccgccaa aaacgccacc gtcgcgttcg cggaaaactc
    55321 tctggaactg ctgatcgccc acgtttgaac gtattccgtt ctaatacagg catctacgct
    55381 caagtgattg atgacgtagc gggtgtaacg ctcgcaagtg cttcaactct tgataaagaa
    55441 gtttcaaaag gaactaaaac tgaacaagcc gttgctgtcg gtaaactcgt tgcagaacgt
    55501 gcaaacgcta aaggtatttc agaagtggtg ttcgaccgcg gtggatatct atatcacgga
    55561 cgtgtgaaag ctttggctga tgcagctcgt gaaaacggat tgaaattcta ataggaggac
    55621 actagaaaat ggcatttaaa gacaatgcag ttgaattaga agaacgcgta gttgctgtca
    55681 accgtgttac aaaagttgtt aaaggtggac gtcgtcttcg tttcgcagct cttgttgttg
    55741 ttggtgacca caatggtcgc gtaggatttg gtactggtaa agctcaagaa gttccagaag
    55801 caatccgtaa agcagtagat gatgctaaga aaaacttgat cgaagttcct atggttggaa
    55861 caacaatccc acacgaagtt ctttcagaat tcggtggagc taaagtattg ttgaaacctg
    55921 ctgtagaagg ttctggagtt gccgctggtg gtgcagttcg tgccgttgtg gaattggcag
    55981 gtgtggcaga tattacatct aaatcacttg gttctaacac tccaatcaac attgttcgtg
    56041 caactgttga aggtttgaaa caattgaaac gcgctgaaga aattgctgcc cttcgtggta
    56101 tttcagtttc tgatttggca taagaaaggg gataaaatgg ctcaaattaa aattactttg
    56161 actaagtctc caatcggacg cattccatca caacgtaaaa ctgttgtagc acttggactt
    56221 ggcaaattga acagctctgt tattaaagaa gataacgctg ctatccgtgg tatgatcaca
    56281 gcagtatctc acttagtaac agttgaagaa gtaaactaat gaagttttag gggatgtgca
    56341 ctgtaccatc ccctaaaact agatatagtc atctatgatg acatcgtata ggcgagttga
    56401 tgggggagac aaccttttct cccttatcgg cgctagcatt ttacaaaaga ggagaaaata
    56461 aaaatgaaac ttcatgaatt gaaacctgca gaaggttctc gtaaagtacg taaccgcgtt
    56521 ggtcgtggta cttcatcagg taacggtaaa acatctggtc gtggtcaaaa aggtcaaaaa
    56581 gctcgtagcg gtggcggagt tcgccttggt tttgaaggtg gacaaactcc attgttccgt
    56641 cgtcttccaa aacgtggatt cactaacatc aacgctaaag aatacgcaat tgtgaacctt
    56701 gaccaattga acgtctttga agatggtgct gaagtaactc cagttgttct tatcgaagca
    56761 ggaattgtta aagctgaaaa gtcaggtatt aaaattcttg gtaacggtga gttgactaag
    56821 aaattgactg tgaaagcagc taaattctct aaatcagctg aagaagctat cactgctaaa
    56881 ggtggttcag tagaagtcat ctaagagagg tgacctatgt tttttaaatt attaagagaa
    56941 gctcttaaag tcaagcaggt tcgatcaaaa attttattta caatttttat cgttttggtc
    57001 tttcgtatcg gaactagcat tacagttcct ggtgtgaatg ccaatagctt gaatgcttta
    57061 agtggattat ccttcttaaa catgttgagc ttggtgtcgg ggaatgccct aaaaaacttt
    57121 tcgatttttg ccctaggagt tagtccctat atcaccgctt ctattgttgt ccaactcttg
    57181 caaatggata ttttacccaa gtttgtagag tggggtaaac aaggggaagt aggtcgaaga
    57241 aaattgaatc aagctactcg ttatattgct ctagttctcg cttttgtgca atctatcggg
    57301 attacagctg gttttaatac cttggctgga gctcaattga ttaaaactgc tttaactcca
    57361 caagtttttc tgacgattgg tatcatctta acagctggta gtatgattgt cacttggttg
    57421 ggtgagcaaa ttacagataa gggatacgga aacggtgttt ccatgattat ctttgccggg
    57481 attgtttcct caattccaga gatgattcag ggcatctatg tggactactt tgtgaacgtc
    57541 ccaagtagcc gtatcacttc atctatcatt ttcgtaatca ttttgattat tactgtattg
    57601 ttgattattt actttacaac ttatgttcaa caagcagaat acaaaattcc aatccaatat
    57661 actaaggttg cacaaggtgc tccatctagc tcttaccttc cgttaaaggt aaatcctgct
    57721 ggagttatcc ctgttatctt tgccagttcg attactgcag cgcctgcggc tattcttcag
    57781 tttttgagtg ccacaggtca tgattgggct tgggtaaggg tagcacaaga gatgttggca
    57841 actacttctc caactggtat tgccatgtat gctttgttga ttattctctt tacattcttc
    57901 tatacgtttg tacagattaa tcctgaaaaa gcagcagaga gcctacaaaa gagtggtgcc
    57961 tatatccatg gagttcgtcc tggtaaaggt acagaagaat atatgtctaa acttcttcgt
    58021 cgtcttgcaa ctgttggttc cctcttcctt ggtgtgattt ccattttacc gattgcagct
    58081 aaagatgtat ttggtctttc tgatgttgtt gcctttggtg gaacaagtct cttgatcatt
    58141 atctctacag gtatcgaagg aatcaagcaa ttggaaggtt acctattgaa acgtaagtat
    58201 gttggtttca tggacagaac agaataaaag tatttactga atcagtaaat gctgagggag
    58261 tggaggttta aactctgaca tttgtaagag ttggatctcc cctcttctat tttgttttta
    58321 aataggggtg aaaagacttt ttgcttctat ttaaaaataa aataaggaga tcaaatcatg
    58381 aatcttttga ttatgggctt acctggtgca ggtaagggaa ctcaagcagc aaaaatcgta
    58441 gaacaattcc atgttgcaca tatctcaaca ggtgatatgt tccgcgctgc aatggtaaat
    58501 caaactgaaa tgggtgttct tgctaagtca tatattgaca agggtgaatt ggttcctgac
    58561 gaagttacaa atggaatcgt aaaagaacgt ctttcacaag atgatattaa agaaacagga
    58621 ttcttattgg atggttaccc acgtacaatt gaacaagctc atgccttgga caaaacattg
    58681 gctgaacttg gcattgaact agaaggtgtt atcaatattg aagtgaaccc tgacagcctc
    58741 ttggaacgtt tgagtggccg tatcatccac cgcgtaactg gagaaacttt ccacaaggtc
    58801 tttaacccac cagttgacta taaagaagaa gattactacc aacgtgaaga tgataagcct
    58861 gagacagtaa aacgtcgttt ggatgttaat attgctcaag gagaaccaat cattgctcac
    58921 taccgtgcca aaggtttggt tcatgacatc gaaggtaatc aagatatcaa tgatgtcttc
    58981 tcagatattg aaaaagtatt gacaaatttg aaataaagcg tttttcacac ttgcaaaaat
    59041 ccgctacaaa tgttatactg agatagtctg acttataatt gttgtctctg tgtctagagg
    59101 catcgaatcg aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg attgaagttg
    59161 aaggcaaagt agttgataca atgccgaatg caatgtttac ggttgaactt gaaaatggac
    59221 atcagatttt agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg
    59281 gagatcgtgt tactgtcgaa atgagtccat atgacttgac acgtggacgt atcacttacc
    59341 gctttaaata atcgaaaaac ttggagggat aagaaatgaa agtaagacca tcggtcaaac
    59401 caatttgcga atactgtaaa gttattcgtc gtaatggtcg tgttatggta atttgcccag
    59461 caaatccaaa acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat
    59521 tgctggagtt gatattccaa atgacaaacg cgtagtaatc tcattgactt atgtttatgg
    59581 tatcggactt gcaacatcta agaaaatttt ggctgctgct ggaatctcag aagatgttcg
    59641 tgtacgtgat cttacatcag atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa
    59701 agttgaaggt gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg
    59761 ttcataccgt ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa atactaaaaa
    59821 caacgctcgc actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa aataatatag
    59881 gaggtaaaag tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct
    59941 ggtattgctc atattcacgc tacatttaat aacactattg ttatgattac tgatgtgcat
    60001 ggtaatgcaa ttgcttggtc atcagctggt gctcttggtt tcaaaggttc tcgtaaatct
    60061 acaccattcg ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca agaacacggt
    60121 cttaaatcag ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt
    60181 gcgcttgctg ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc agtgccacac
    60241 aatggtgctc gtcctccaaa acgtcgccgt gtataatcat cgcattacac tgcttttcgt
    60301 ttaagaggga gtaactaaat gatcgagttt gaaaaaccaa atataacaaa aattgatgaa
    60361 aataaagatt atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg tacaactctt
    60421 ggtaactctc ttcgtcgtgt acttctagct tctctaccag gagcagctgt gacatctatc
    60481 aacattgatg gtgtgttaca tgagtttgac acagttccag gtgttcgtga agacgtgatg
    60541 caaatcattc tgaacattaa aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc
    60601 atcgaactgg atgttgaagg tcctgctgaa gtaacagctg gtgacatttt gacagatagc
    60661 gatattgaaa ttgtaaatcc agatcattat ctctttacaa tcggtgaagg ttcttctcta
    60721 aaagcgacta tgactgttaa cagtggtcgt ggatatgtac ctgctgatga aaataaaaag
    60781 gataatgcac cagttggaac acttgctgta gattctattt atacaccagt tacaaaagtc
    60841 aactatcaag tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt
    60901 gaaatcttga caaatggaac aattattcca gaagatgctt tagggctttc agcacgtatt
    60961 ttgacagaac atcttgattt gtttacaaat cttactgaga ttgctaagtc aactgaagtg
    61021 atgaaagaag ctgatactga atctgacgac cgtattttag atcgtacgat tgaggaactg
    61081 gacttgtctg tgcgttcata caactgttta aaacgtgccg gtatcaatac tgtgcatgat
    61141 ttgacagaaa aatctgaagc agagatgatg aaagtacgaa atcttggacg caagagtttg
    61201 gaagaagtga aactcaaact cattgatttg ggtcttggat taaaagataa ataaaggagg
    61261 aatacatggc ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgcg
    61321 atttgacaac tgaccttttg atcaacgaat caatcgtgac aactgaagct cgtgctaaag
    61381 aaatccgtaa aactgttgaa aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac
    61441 gtcgtcaagc agctgctttc gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa
    61501 ctgataagta cacttctact acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt
    61561 atgctgaacg taacggtgga tacactcgta tccttaaaac tgaaccacgt cgtggtgatg
    61621 cagcgccaat ggcgatcatc gaattagtat aaaatcatca attttgttga gtgttatgat
    61681 gatggagtct tgtgctctta gtctagctct ggtctaccgc taggatttcg gtcctagcgg
    61741 gaacactcat cataagttgg gatagtagac gcttgtttac gaaattgttt ttttcttaag
    61801 aacaacttcg taagcaggcg tttttgagta ttttcgttag aattatgcta tactatttga
    61861 aaagaatcct gtttaatgtt aaggtttctt attttaagaa gaattggagt ttacttatga
    61921 aagccattat aactgttgtt ggtaaagata aatctggaat tgttgcaggt gtttctggta
    61981 aaattgcaga attaggattg aatattgacg atatctctca aactgtcttg gatgaatatt
    62041 ttacgatgat ggctgttgta tctagtgatg aaaagcaaga ttttacctat cttcgtaatg
    62101 aatttgaagc ttttgggcaa actttgaatg taaaaatcaa tattcagagt gcagcgattt
    62161 tcgaagctat gtataatatc taggaggtta tcatggatat tagacaagtt actgaaacca
    62221 tcgccatgat tgaggagcaa aacttcgata ttagaaccat taccatgggg atttctcttt
    62281 tggactgtat cgatccagat atcaatcgtg ctgcggagaa aatctatcaa aaaattacga
    62341 caaaggcggc taatttagta gctgttggtg atgaaattgc ggctgagttg ggaattccta
    62401 tcgttaataa gcgtgtatcg gtgacaccta tttctctgat tggggcagcg acagatgcga
    62461 cggactacgt ggttctggca aaagcgcttg ataaggctgc gaaagagatt ggtgtggact
    62521 ttattggtgg tttttctgcc ttagtacaaa aaggttatca aaagggagat gagattctca
    62581 tcaattccat tcctcgcgct ttgactgaga cggataaggt ctgctcgtca gtcaatatcg
    62641 gctcaaccaa gtctggtatt aatatgacgg ctgtggcaga tatgggacga attatcaagg
    62701 aaacggcaaa tctttcagat atgggagcgg ccaagttggt tgtattcgct aatgctgttg
    62761 aggacaatcc atttatggcg ggtgcctttc atggtgttgg ggaagcagat gttatcatca
    62821 atgtcggagt ttctggtcct ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga
    62881 gctttgatgt agtagccgaa acagttaaga aaactgcctt taaaatcact cgtatcggtc
    62941 aattggttgg tcaaatggcc agtgagagac tgggtgtgga gtttggtatt gtggacttga
    63001 gtttggcacc aacccctgcg gttggagact ctgtggcacg tgtccttgag gaaatggggc
    63061 tagaaacagt tggcacgcat ggaacgacag ctgccttggc cctcttgaac gaccaagtta
    63121 aaaagggtgg agtgatggcc tgtaaccagg tcggtggtct atctggtgcc tttatccctg
    63181 tttctgagga tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac
    63241 tagaagctat gacggctatc tgttctgttg gattggatat gattgccatc ccagaagata
    63301 cgcctgctga aactattgcg gctatgattg cggatgaagc agcaatcggt gttatcaaca
    63361 tgaaaacaac agctgttcgt atcattccca aaggaagaga aggcgatatg attgagtttg
    63421 gtggtctatt aggaactgca cccgttatga aggttaatgg ggcttcgtct gtcgacttca
    63481 tctctcgcgg tggacaaatc ccagcaccaa ttcatagttt taaaaattaa gaaaatagga
    63541 gaaattttaa gttctattta agattagatg tgtatactat aatcattaaa taaagacctc
    63601 ctaatattat ttgaaacaga taacactgaa ttagtttgaa tttgattttc atctaatatc
    63661 tttatttaat gaactcctaa actttttcat aataatctcc ttcaaaagtc gcctgtatgg
    63721 gtggctttta ttttatcatt catgatataa tagaagcaaa cggaggacgg aaaatggtaa
    63781 aagtacgatt gtatttggta cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc
    63841 aaggttggag cgatactccc ttaactgctg aaggtgaacg agggattcaa gagttaggaa
    63901 ctggtttgcg agaatctgat ctacagtttg agcgcgctta ttcgagtgat tctggtcgta
    63961 ccattcagac catgggaatt atccttgaag aacttggctt gcaggggaaa atcccttatc
    64021 gcatggacaa gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc tatgatggcg
    64081 atcttttcat gggcattatt cctcgtatct ttaatgtgga ccacgttcac caattgtctt
    64141 atgctgaact ggctgagggc ttggtagagg tcgatacagc tggttgggct gaaggctggg
    64201 aaaaactcag tggccgaatc aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc
    64261 aaggtggagg taacgccctt gttgtcagcc atggaatgac tattggaacc attgtttatc
    64321 tgattaatgg catgcatccg catggtctag ataatggtag cgtgacgatt cttgaatatg
    64381 aggacggtca gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag ctaggacgtg
    64441 agaagatgga agaaggctct atttaatcag tctagacttg cttgccatga gctagggatt
    64501 tgataagaat atcaagataa gaaaaaacag ccgagggtac tcctttcggc tgtttttgat
    64561 gtggaaaact aaagtgtaat gctattgctt ttagagattt tcataaacaa gagcaaggaa
    64621 cctactgtta gaacagtcag gatagttgac aaggctgcgg ctacaccgta atttcctctg
    64681 agaacctctg tataaatagc tacagtcatt gttcttgttt tgacattgta gaggaggata
    64741 gaagtagaga gttttgaaat cattgtgacc caagataaga tggctccaga aatgatacca
    64801 gatagcatca ttggagttgt aatcttagca aaggtattga gacgactact tcctaagctt
    64861 tcagcagctt cttcaatact tggtgctatt tgttgtaagc tagcaacaga tgagcgaata
    64921 gtataaggta atcttctgac agatagagac ataatcaaga tgaaagcagt ccctgtaatc
    64981 ataagaaatc cacttccaaa tagaccagag aaatgaaggc aatccctaga acggttcctg
    65041 gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc
    65101 taacggctag gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag
    65161 ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt
    65221 ttggagaata acctttaaca aataccatac ctgatgtttt taggaaagag gtataaatta
    65281 agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag
    65341 ccatttttcc ttttgtagtt tttttaggct caattggatg gatcagattc atgctgaaac
    65401 tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca
    65461 taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag
    65521 ggaaagtccg atatccttcg ccaatcaaca taggcgttcc aaagtctgag aatgctctca
    65581 taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac
    65641 gataggttta aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat
    65701 actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac
    65761 aagtacaatt cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa
    65821 aaatttagtg atgacctcat ttcgtcccag caagagaatc caggagtagg ctcctacgaa
    65881 aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc
    65941 atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga tagtagcggt
    66001 aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac taaagaaagt
    66061 gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga gcacggtaac
    66121 gataggataa acgagaaaga taggataggt aagaaagagg aagaaagagg aagctgtcca
    66181 aatatttagt tttttacgtt ccatggttga ctccttttat caggttttgg gaaccatctg
    66241 cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta
    66301 gatcttcttc aaaagttgat tcttcactaa cttgaatttt tgaggcaaaa cctgtctcaa
    66361 tgaaataatc cgtatttagt ccaagataga cgctatctct aatagttcct tcaatatctc
    66421 cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa
    66481 cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata taagcgccgt
    66541 cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa
    66601 actcattagc tggtttatga tagagttctt ttggtcggcc gatttgttgg atcaccccat
    66661 ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat
    66721 aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc
    66781 gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg
    66841 ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc
    66901 aatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt
    66961 cttcttttgg aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
    67021 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
    67081 tattgatttt tgtatcatcg aagtaaaatt ctccatcttt gatactgttg aaacctgcaa
    67141 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
    67201 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
    67261 cgttaataat ttcgatctca ttcatagtga acctctttta ctgtttagat tggatatctg
    67321 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
    67381 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
    67441 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
    67501 taaaatcgat aaatttcttg gcattttcca tatttttagc ttttttaacg atagcagcac
    67561 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
    67621 ttaagagttt aactgctgga tcttcataag agagaccaac agccatttct ccatcagcga
    67681 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
    67741 tacacatcta cttctaaaat attgttagaa atcgatttga ctgtcctgat tgatttgtcc
    67801 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
    67861 aagccttatc atctttgtaa ccaccttgat cttgtagcat atttgttaat tgagcaaagg
    67921 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
    67981 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
    68041 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
    68101 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
    68161 aagaaccacc aaagataaca tcagctacag gaacttcttt ttctgactct agttttttga
    68221 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
    68281 caggaatagt tgctccaatt aagccttctg agtttggtca ataaacgact agcgaaccac
    68341 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
    68401 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
    68461 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataa
//
LOCUS       DAVHSL010000005        58902 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000005 DAVHSL010000000
VERSION     DAVHSL010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.005"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..138)
                     /locus_tag="VVR39_000300"
     CDS             complement(<1..138)
                     /locus_tag="VVR39_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6029852.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HT"
     gene            845..2320
                     /locus_tag="VVR39_000301"
     CDS             845..2320
                     /locus_tag="VVR39_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU6029853.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGSSHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(2286..2876)
                     /locus_tag="VVR39_000302"
     CDS             complement(2286..2876)
                     /locus_tag="VVR39_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6029854.1"
                     /translation="MSLRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIK
                     KFAKSLLLRKTKTDKKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTCYPNPQKRIEAGFDKLIEIKRLTAS
                     NSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSFS"
     gene            3256..4116
                     /gene="speE"
                     /locus_tag="VVR39_000303"
     CDS             3256..4116
                     /gene="speE"
                     /locus_tag="VVR39_000303"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU6029855.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            4113..5372
                     /locus_tag="VVR39_000304"
     CDS             4113..5372
                     /locus_tag="VVR39_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU6029856.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            5372..6499
                     /gene="nspC"
                     /locus_tag="VVR39_000305"
     CDS             5372..6499
                     /gene="nspC"
                     /locus_tag="VVR39_000305"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU6029857.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6496..7581
                     /gene="aguA"
                     /locus_tag="VVR39_000306"
     CDS             6496..7581
                     /gene="aguA"
                     /locus_tag="VVR39_000306"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU6029858.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7591..8466
                     /gene="aguB"
                     /locus_tag="VVR39_000307"
     CDS             7591..8466
                     /gene="aguB"
                     /locus_tag="VVR39_000307"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU6029859.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8647..9456)
                     /locus_tag="VVR39_000308"
     CDS             complement(8647..9456)
                     /locus_tag="VVR39_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6029860.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9728..9949
                     /locus_tag="VVR39_000309"
     CDS             9728..9949
                     /locus_tag="VVR39_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU6029861.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            10003..10674
                     /locus_tag="VVR39_000310"
     CDS             10003..10674
                     /locus_tag="VVR39_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6029862.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10726..10923)
                     /locus_tag="VVR39_000311"
     CDS             complement(10726..10923)
                     /locus_tag="VVR39_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6029863.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            10916..11824
                     /locus_tag="VVR39_000312"
     CDS             10916..11824
                     /locus_tag="VVR39_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6029864.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11821..12282
                     /locus_tag="VVR39_000313"
     CDS             11821..12282
                     /locus_tag="VVR39_000313"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU6029865.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAILKEEINGN"
     gene            12272..13159
                     /locus_tag="VVR39_000314"
     CDS             12272..13159
                     /locus_tag="VVR39_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6029866.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            13162..15045
                     /gene="cbpE"
                     /locus_tag="VVR39_000315"
                     /gene_synonym="pce"
     CDS             13162..15045
                     /gene="cbpE"
                     /locus_tag="VVR39_000315"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU6029867.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRHLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKEKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            15125..16255
                     /locus_tag="VVR39_000316"
     CDS             15125..16255
                     /locus_tag="VVR39_000316"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU6029868.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            16265..17527
                     /locus_tag="VVR39_000317"
     CDS             16265..17527
                     /locus_tag="VVR39_000317"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU6029869.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEILLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17531..18328
                     /gene="proC"
                     /locus_tag="VVR39_000318"
     CDS             17531..18328
                     /gene="proC"
                     /locus_tag="VVR39_000318"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU6029870.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLSRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18548..19186
                     /locus_tag="VVR39_000319"
     CDS             18548..19186
                     /locus_tag="VVR39_000319"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU6029871.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            19183..20073
                     /locus_tag="VVR39_000320"
     CDS             19183..20073
                     /locus_tag="VVR39_000320"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU6029872.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            20113..20430
                     /gene="yabA"
                     /locus_tag="VVR39_000321"
     CDS             20113..20430
                     /gene="yabA"
                     /locus_tag="VVR39_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU6029873.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20433..21302
                     /gene="rsmI"
                     /locus_tag="VVR39_000322"
     CDS             20433..21302
                     /gene="rsmI"
                     /locus_tag="VVR39_000322"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU6029874.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            21529..22047
                     /locus_tag="VVR39_000323"
     CDS             21529..22047
                     /locus_tag="VVR39_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU6029875.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            22156..22803
                     /locus_tag="VVR39_000324"
     CDS             22156..22803
                     /locus_tag="VVR39_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6029876.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(22792..23595)
                     /locus_tag="VVR39_000325"
                     /pseudo
     CDS             complement(22792..23595)
                     /locus_tag="VVR39_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23590..23844
                     /locus_tag="VVR39_000326"
     CDS             23590..23844
                     /locus_tag="VVR39_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6029877.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            24089..25423
                     /gene="trmFO"
                     /locus_tag="VVR39_000327"
     CDS             24089..25423
                     /gene="trmFO"
                     /locus_tag="VVR39_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU6029878.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            25507..26244
                     /locus_tag="VVR39_000328"
     CDS             25507..26244
                     /locus_tag="VVR39_000328"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU6029879.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRSAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            26253..26810
                     /gene="frr"
                     /locus_tag="VVR39_000329"
     CDS             26253..26810
                     /gene="frr"
                     /locus_tag="VVR39_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU6029880.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            26870..27724
                     /gene="cvfB"
                     /locus_tag="VVR39_000330"
     CDS             26870..27724
                     /gene="cvfB"
                     /locus_tag="VVR39_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU6029881.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPEFKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            27733..27948
                     /locus_tag="VVR39_000331"
     CDS             27733..27948
                     /locus_tag="VVR39_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU6029882.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            28034..29002
                     /locus_tag="VVR39_000332"
     CDS             28034..29002
                     /locus_tag="VVR39_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU6029883.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(28980..29159)
                     /locus_tag="VVR39_000333"
     CDS             complement(28980..29159)
                     /locus_tag="VVR39_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029884.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            29195..29695
                     /locus_tag="VVR39_000334"
     CDS             29195..29695
                     /locus_tag="VVR39_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029885.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            29698..29958
                     /locus_tag="VVR39_000335"
                     /pseudo
     CDS             29698..29958
                     /locus_tag="VVR39_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(30325..30651)
                     /locus_tag="VVR39_000336"
     CDS             complement(30325..30651)
                     /locus_tag="VVR39_000336"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029886.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTNLPVAQGLNRDYT
                     DINDLV"
     gene            complement(30597..31010)
                     /locus_tag="VVR39_000337"
     CDS             complement(30597..31010)
                     /locus_tag="VVR39_000337"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU6029887.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(31011..31436)
                     /locus_tag="VVR39_000338"
     CDS             complement(31011..31436)
                     /locus_tag="VVR39_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU6029888.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            31613..32182
                     /locus_tag="VVR39_000339"
     CDS             31613..32182
                     /locus_tag="VVR39_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6029889.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            32250..32900
                     /locus_tag="VVR39_000340"
     CDS             32250..32900
                     /locus_tag="VVR39_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU6029890.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEEEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            32884..35124
                     /locus_tag="VVR39_000341"
     CDS             32884..35124
                     /locus_tag="VVR39_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU6029891.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMSELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGKGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPRE
                     IGYGGHEDSLVLYGKLLNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            35266..35490
                     /locus_tag="VVR39_000342"
     CDS             35266..35490
                     /locus_tag="VVR39_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029892.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEVINYYSGGY"
     gene            35522..36109
                     /locus_tag="VVR39_000343"
     CDS             35522..36109
                     /locus_tag="VVR39_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029893.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            36113..37297
                     /locus_tag="VVR39_000344"
     CDS             36113..37297
                     /locus_tag="VVR39_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6029894.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTAISGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIIFLLVGILFIENWGSSRKKEVFN
                     RS"
     misc_feature    37452..37583
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            37599..38129
                     /gene="infC"
                     /locus_tag="VVR39_000345"
     CDS             37599..38129
                     /gene="infC"
                     /locus_tag="VVR39_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU6029895.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            38162..38362
                     /gene="rpmI"
                     /locus_tag="VVR39_000346"
     CDS             38162..38362
                     /gene="rpmI"
                     /locus_tag="VVR39_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU6029896.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            38414..38773
                     /gene="rplT"
                     /locus_tag="VVR39_000347"
     CDS             38414..38773
                     /gene="rplT"
                     /locus_tag="VVR39_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU6029897.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            38831..39211
                     /locus_tag="VVR39_000348"
     CDS             38831..39211
                     /locus_tag="VVR39_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6029898.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            39461..40261
                     /locus_tag="VVR39_000349"
     CDS             39461..40261
                     /locus_tag="VVR39_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU6029899.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            40224..41210
                     /locus_tag="VVR39_000350"
     CDS             40224..41210
                     /locus_tag="VVR39_000350"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU6029900.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            41252..43417
                     /gene="lytB"
                     /locus_tag="VVR39_000351"
     CDS             41252..43417
                     /gene="lytB"
                     /locus_tag="VVR39_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU6029901.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFHLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(43478..45133)
                     /gene="pavA"
                     /locus_tag="VVR39_000352"
     CDS             complement(43478..45133)
                     /gene="pavA"
                     /locus_tag="VVR39_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU6029902.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            45238..45735
                     /gene="ybeY"
                     /locus_tag="VVR39_000353"
     CDS             45238..45735
                     /gene="ybeY"
                     /locus_tag="VVR39_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU6029903.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            45716..46111
                     /locus_tag="VVR39_000354"
     CDS             45716..46111
                     /locus_tag="VVR39_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU6029904.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            46128..47027
                     /gene="era"
                     /locus_tag="VVR39_000355"
     CDS             46128..47027
                     /gene="era"
                     /locus_tag="VVR39_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU6029905.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            47076..47900
                     /gene="mutM"
                     /locus_tag="VVR39_000356"
     CDS             47076..47900
                     /gene="mutM"
                     /locus_tag="VVR39_000356"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU6029906.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQSLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            47900..48505
                     /locus_tag="VVR39_000357"
     CDS             47900..48505
                     /locus_tag="VVR39_000357"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU6029907.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            48492..49691
                     /locus_tag="VVR39_000358"
     CDS             48492..49691
                     /locus_tag="VVR39_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU6029908.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYYAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            49691..49840
                     /gene="rpmG"
                     /locus_tag="VVR39_000359"
     CDS             49691..49840
                     /gene="rpmG"
                     /locus_tag="VVR39_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6029909.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            49880..50113
                     /gene="secG"
                     /locus_tag="VVR39_000360"
     CDS             49880..50113
                     /gene="secG"
                     /locus_tag="VVR39_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU6029910.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            50215..52569
                     /gene="rnr"
                     /locus_tag="VVR39_000361"
     CDS             50215..52569
                     /gene="rnr"
                     /locus_tag="VVR39_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU6029911.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQGKPKYVGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEVSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            52532..52999
                     /gene="smpB"
                     /locus_tag="VVR39_000362"
     CDS             52532..52999
                     /gene="smpB"
                     /locus_tag="VVR39_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU6029912.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLYKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            53015..53875
                     /gene="tehB"
                     /locus_tag="VVR39_000363"
     CDS             53015..53875
                     /gene="tehB"
                     /locus_tag="VVR39_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU6029913.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGAIK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            53948..54901
                     /gene="coiA"
                     /locus_tag="VVR39_000364"
     CDS             53948..54901
                     /gene="coiA"
                     /locus_tag="VVR39_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU6029914.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     DLEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTNYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVK"
     gene            54920..56722
                     /gene="pepF"
                     /locus_tag="VVR39_000365"
     CDS             54920..56722
                     /gene="pepF"
                     /locus_tag="VVR39_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6029915.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            56724..57437
                     /locus_tag="VVR39_000366"
     CDS             56724..57437
                     /locus_tag="VVR39_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU6029916.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKKVADVQLSESE"
     gene            57504..58445
                     /gene="prsA"
                     /locus_tag="VVR39_000367"
     CDS             57504..58445
                     /gene="prsA"
                     /locus_tag="VVR39_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU6029917.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(58562..>58902)
                     /locus_tag="VVR39_000368"
     CDS             complement(58562..>58902)
                     /locus_tag="VVR39_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6029918.1"
                     /translation="LEQAFKEKHYENTILHSDQDWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLS
                     PVQYRTKSFG"
BASE COUNT        17697 a        10781 c        13321 g        17103 t
ORIGIN      
        1 agtgtggata gtttgaggag cttttccaag tagagaggca atttctctat ttgattttcc
       61 ttcttttttc catctttcga ttaagcgacg gctatcgatt gtcaaatgtt taccttttgt
      121 agtataattg tcttgcattt ctgtgccttt cttgtgtttg tggttgaaca acaagtataa
      181 cacagaggtg ttttcttatg cctacaagag ctttcagcta gttgaaccat ctaattttta
      241 ggagggctgg gtggctaact tcattataga actttcattt acgaacatat agtaaaatga
      301 aacaagaaca gaacaaatcg atcaggacag taaaatcgaa ttctaacaat gttttagaag
      361 tagaggtgta ctattctagt ttcaatctac tatattttta ttttttatca aaaaatactt
      421 tacaagttct taaaaacatg atatagtaat aaagcttaga aaatgagatg atgttttcta
      481 gcaaatataa acccgagtaa aaaatgccta cggacaggca gggttgaatg ccgaagcgtg
      541 gttgaaaagc cacattattg atagggttaa aagcctactt ttataagttg atgttaggac
      601 acttgttcta attcataaat ttttagtgtg gtgaaagcac acgtcatctt gtgaaacgat
      661 caataaagta cgtaatattt gctactagag agttaggaaa catcgggaac agacatactc
      721 aacagaaacc aaaataaaca cgtcagaaga ttgcagagca ggtgaaaacc tgctcttttt
      781 tcatgagtca acctttagtt ccttagtttt cataaggtcc taaaaatatt gaaaggagta
      841 tgttttgaaa gagttagatc aaaaccaagc cccaatttat gaggccttgg tgaagttacg
      901 caagaaaagg attgttccct ttgatgttcc aggtcacaag cgtggacggg gaaatccaga
      961 acttgtcgaa ctcttaggag aaaaatgtgt aggcattgat gtcaattcga tgaaaccctt
     1021 ggataattta ggccatccta tttcgattat tcgtgatgca gaggagctgg ctgcagatgc
     1081 ttttggatct agccatgcct ttctaatgat tggtggaaca acttcatcgg tgcagactat
     1141 gattctggca acctgcaagg caggagataa gattattctg ccacgaaatg tccataaatc
     1201 tgctatcaat gcgttggttc tatgtggtgc cattcccatc tatatcgaga tgagtgtaga
     1261 tcctaagatt ggtatcgctt taggtcttga aaatgaccga gtagcacagg ccataaagga
     1321 ccatccagat gctaaggcta tcctaatcaa caatcctact tactacggca tctgttcaga
     1381 cctaaagggg ttgacagaaa tggctcatga agctggcatg atggttttag tagatgaagc
     1441 ccacggagcg catttgcatt tcactggtaa acttccaatt tctgctatgg atgcaggagc
     1501 tgatatggca gcagtttcca tgcataagtc tggtgggagt ttgacacaaa gttcgcttct
     1561 tttaatcggg gagcagatga atcccgagta cgttcgtcag attataaacc tgacccagtc
     1621 tacatctgcc tcttacttat tgatggctag tttggatatt tcacgtcgca acttggccct
     1681 tcgtggtaaa gagtcgtttg aggaagtcat tgagctatcc gagtacgctc gtcatgaaat
     1741 caatgccatt ggcggttact atgcttactc aaaagagtta atagatggtg tgtcggtctg
     1801 tgattttgat gtaaccaagt tgtcagttta cactcaggga ataggcttaa caggtatcga
     1861 ggtttatgac ctcttgcgag acgaatacga cattcagatc gagtttggtg atatcggcaa
     1921 tatcttggcc tatatttcca tcggcgaccg catccaagac atcgagcgct tggttggtgc
     1981 tctggctgat attaagagac tctattcacg agatgggaag gacttaatag ctggagaata
     2041 tattcagccc gagttggtgc tgtctccaca agaagccttc tattcagaga gaaaaagttt
     2101 gaccttagat gagtctgttg gacaggtctg tggagaattt gtcatgtgct atcctccagg
     2161 gattcctatc ttggctcctg gtgaacgcat tacacgagaa attgtagact atatccaatt
     2221 cgccaaggaa cgtggttgct ccctccaagg gacggaagat ccagaggtca atcatatcaa
     2281 cgttattaag agaaagacaa actataagaa aagtcaatag ttttatctaa actatttctt
     2341 atttcaattt gatgatttgg cgatgatttt agagcacggc aaaaagccct tgaattagaa
     2401 gcggtcaatc gcttaatttc tatcagctta tcaaatcctg cctcaatcct tttctgagga
     2461 ttagggtagc atgtcaagag ttggtaggta tattctgaat gctttccaac gattttatcc
     2521 aactcaggaa agatgatatc aagacaacga gtgtattgca ctttccaatc agactgtttt
     2581 ttcttgagac gatgaatatg tctagccagt atttttagtt ctacttgccg attatcgtgt
     2641 tgaaattgtt cacgattggg atcagaaaga agtttaagag cgatgccatg agcgtctttc
     2701 ttatccgttt tagtcttgcg aagtaataat gatttggcaa atttcttgat gagcaaagga
     2761 ttgtaggtgt aaactttata tccttgttca tgcaggaagt tcagtagatt aaaggcataa
     2821 tgtccagtat cttcaagagc gatgagacag tcttggttga gctgtcgaag agacagatct
     2881 aagagttcaa aaccagcttt attatttgaa aaagtgagtg gtttaagaac agttttcctg
     2941 gaacattcaa ggctgtaaca tcgtgtttat ttttagcgac atcaatgccc acataaagca
     3001 tgggagtacc tccagatata gtatttcaag tctacttggt tatccacgaa ctttttgcct
     3061 tgttacctta gacgagataa aacgtctatg cgttatcaaa ctcattacca attgaaacaa
     3121 aagctgtggt tagagccttt cggaaatcgt caagcgattg gagggaataa actaatccac
     3181 agtggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa
     3241 tataaggaga aatagatgga tttatggttt tctgaagttc atactccaga tgtcaaattg
     3301 tctctgagaa cagccaagca actttacgct ggaaaaagtg aatggcagga tatcgaagtc
     3361 ttggatacgc cagcttttgg gaaaatactg attttaaatg gccatgtctt gttctcagat
     3421 gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc ccatggctgt ccacccaaat
     3481 ccaaagaaag tattggttat tgggggtggt gacggcggtg ttgcccaagt attaacactc
     3541 tatcctgaac tggaacaaat cgatatcgtg gaaccggatg agatgttggt cgaggtctgt
     3601 cgtgagtatt tcccagactt tgctgcaggg ctagatgatc ctcgtgttac catttactac
     3661 caaaatgggc tacgcttttt gcgaaactgc gaagatgatt acgatattat catcaacgat
     3721 gcgacagatc catttggcca tacggaagga ctctttacca aggaattcta cggcaatagt
     3781 tatcgagctc tgaaggaaga cggcatcatg atttaccagc atgggagtcc cttctttgac
     3841 gaggatgagt cggcctgccg aagcatgcac cgcaaggtca atcaatcctt tccaatcagt
     3901 cgggtttatc aggcccatat tccaactagc ccagctggct attggttgtt tggatttgca
     3961 tcgaaaaaat accaccctgt caaagatttt gacaaggaag gttggaaaaa acgccagctt
     4021 ttcacagaat actacactgc aaacttacac gtgggatcct ttatgttgcc caagtatgtt
     4081 gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg tttactagtt attggttgtg
     4141 ggggcgttgc ccaagttgct atttcaaaga tttgtcaaga tagcgaaaca tttacagaga
     4201 ttatgattgc tagccgtacc aagtcaaaat gcgatgactt gaaagcgaag ctagaaggca
     4261 aaacaagtac taaaattgaa actgcagcac ttgatgctga caaggttgaa gaagtgattg
     4321 ccctgattga aagctacaaa ccagaagctg ttttgaatgt agctctgcct tatcaagatt
     4381 taaccattat ggatgcttgt ttggcaacag gtgttcacta tatcgataca gccaactacg
     4441 aagcagaaga cacagaagac cctgagtggc gtgctatcta cgaaaaacgt tgtaaggaac
     4501 ttggttttac agcctacttt gactactcat ggcagtgggc ttatcaagag aaattcaaag
     4561 aagcaggctt gactgctctt cttggttctg gttttgaccc aggtgtaact agtgtctttt
     4621 cagcttatgc cctcaaacac tattttgatg aaatccatta tatcgacatt ttagactgta
     4681 atggcggtga ccacggttat ccatttgcaa ccaactttaa tccagaaatt aatctccgtg
     4741 aggtttctgc gccaggttct tactgggaag atgggaaatg ggtcgaagtc gaagctatgt
     4801 ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa agatatgtat ctccttcacc
     4861 atgaagaaat cgaatcattg gccaagaaca ttccaggtgt caaacgcatt cgtttcttta
     4921 tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct tgaaaatgtt ggactccttc
     4981 gtacggatac cattaacttt aacggccaag aaattgttcc aattcaattt ttgaaagcct
     5041 tgcttccaga tcctgccagt cttgggccac gtacagtcgg aaaaaccaat attggatgta
     5101 tctttacagg tgtcaaagac ggtgtcaaaa agactatcta tatctacaat gtctgcgacc
     5161 atcaggaatg ttacgcagag gttggttcgc aagctatttc ttatacgaca ggagttccag
     5221 ccatgattgg gacaaaatta gtcatgaacg gaacttggaa acaagctgga gtgtataacc
     5281 ttgaggagtt agatccagat ccattcatgg aagctttgaa tgagtatggt ttgccatggg
     5341 ttgtggttga aaatccacaa atggtggact aatgaagtta gaacaagtac caacaccagc
     5401 ctatgttatt gacttggcca agttagaagc taattgccgc attctacaat atgtacaaga
     5461 agaggtcggt tgcaaggtct tgcttgccca gaaggcatat tccctctaca aaacttatcc
     5521 cttgattagc cagtatctat caggtacgac agctagtgga ctctatgagg ccaaattggc
     5581 aagggaagaa tttcctggtg aagtccatgt atttgcgcct gctttcaagg atgcagactt
     5641 ggaggaattg cttgggataa cagaccatat cgtctttaac tcagagagac agttgcgtaa
     5701 gcatggggct cgttgtcgag aggctggtgt cagtgttggt ttgcgcctca accctcagtg
     5761 ttcaactcaa ggagatcacg cgctctatga cccttgtgca ccaggttctc gctttggagt
     5821 tactatagac aagattccga gtgatttgct agatttggtt gacggacttc attttcatac
     5881 cctttgcgag cagggagcag atgatttaca aacaactttg aaagcagtag aagaacagtt
     5941 tggtccctac ttacatgagg taaaatggct caatatgggt ggtggtcatc atattacaag
     6001 agaaggttac gatgtggatt tgctgatttc agaaatcaag cgtatccgaa aaacttacaa
     6061 tcttgaaata tatatcgagc ctggtgaagc cattgcgctt aatgcgggtt atttagcaac
     6121 tgaggtatta gatattgtag aaaacggtat ggaaatcttg gttttagacg cctctgcgac
     6181 ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca cctttgagaa atggctttga
     6241 ggcacaggaa aaagcccata cctacagact ttcttctaat acttgtctga ctggcgatgt
     6301 gattggtgat tatagttttg aaaatccagt ccaaatcgga gacagacttt attttcaaga
     6361 catggccatt tattcttttg tcaaaaataa tacctttaat ggtattggat taccaagtct
     6421 ctatctcatg gacgaacagg gagactgtag cttactcaaa gcttttggct atcaagactt
     6481 taaagggaga ttatcatgat ggacagtcca aaaaaattag gctatcacat gccagcagag
     6541 tacgaacccc atcatggtac cctcatgata tggccgactc gaccaggatc atggcctttt
     6601 caaggaaagg ctgctaaaag agcatttact cagatcatcg agaccatagc agaaggggaa
     6661 agagtctatc ttttggtgga gcaggcctat ctatctgaag cccaatccta tcttggagac
     6721 aaggttgttt atttagacat tcccaccaat gatgcctggg cgcgtgatac tggcccaacc
     6781 attctcgtca atgataaagg taagaaatta gccgtggatt gggcctttaa tgcttgggga
     6841 ggcacctatg atggtcttta tcaagattat gaagaggatg accaagtagc cagtcgtttt
     6901 gctgaggcct tggaaaggcc tgtctatgat gctaaacctt ttgtactgga aggaggcgca
     6961 atccatagcg atggtcaagg aactattctc gtaactgaaa gttgcttgct tagtcctggt
     7021 cgcaatccta acctgactaa agaggagatt gaaaacacat tattagaaag tcttggtgct
     7081 gaaaaagtta tttggcttcc ttatggtatt tatcaggatg aaaccaatga acacgtcgat
     7141 aatgttgctg cctttgttgg tcctgctgag cttgttttgg cttggacaga tgacgaaaat
     7201 gatccccagt atgccatgtc aaaagcagat ctcgaactct tagaacagga aacagatgca
     7261 aaaggttgtc acttcaccat tcataaattg cctatccctg cagttcgaca agttgtgaca
     7321 gaagaagatt tgccaggcta catctatgaa gaaggagaag aaaagcgata cgcaggtgaa
     7381 cgactagcag cttcctacgt aaacttttat atcgccaaca aggctgtctt ggttccacag
     7441 tttgaggatg taaacgacca agtggcctta gatatcctca gcaagtgttt cccagaccgt
     7501 aaagttgtcg gaataccagc cagagatatt ctcttaggtg gtggcaatat ccactgtatc
     7561 acccaacaaa ttccagaata ggagaaaaag atgagaaatg taagagttgc aaccattcag
     7621 atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg cagagcgttt agtacgtcag
     7681 gctgctgagc aaggagccca aattattctc ttgcccgagt tgtttgaaca tccctatttc
     7741 tgtcaggaac gtcagtatga ctactaccag tatgcccaat ctgtagcgga aaatactgcc
     7801 attcagcatt ttaaggtgat tgctaaggaa ctacaagttg ttttaccaat cagtttctat
     7861 gaaaaagatg gtaatgtctt gtataactct attgccgtca ttgatgcaga tggggaagtg
     7921 ctgggcgttt atcgaaagac ccatatacca gatgaccatt attatcaaga aaaattctat
     7981 ttcacgcctg gtaacactgg tttcaaggtc tggaatactc gctatgctaa gattggtatc
     8041 ggtatctgtt gggatcaatg gttccctgaa acagcgcgct gtcttgcatt gaatggtgct
     8101 gaattgctct tttatcctac agctatcggt tcagagccaa ttttggatac agatagttgt
     8161 ggtcactggc aacgtactat gcaagggcac gcagcagcga atattgttcc agtcatcgca
     8221 gccaatcgtt atggtttaga ggaggttact cctagtgagg aaaatggcgg acagagttcc
     8281 agtcttgact tctacggttc ctcctttatg acggatgaaa caggagctat tctagaacga
     8341 gctgaaagac aagaagaagc tgttctgtta gctacttatg acctagacaa gggagcaagt
     8401 gaacgcctaa actggggctt gtttcgagat agaagaccag aaatgtatag acaaattaca
     8461 gattagtgtg ggagaaatga gagattcatt ctgctagact aacttcttat tagcaactat
     8521 aagatactat ggcatctagt aaatcgattt ttatgattcg ctattcttgt ctattgatta
     8581 gtccgtattt taaaatatta gcaaaaaagc aaatagcagt aacttctgtc tatttgcttt
     8641 tcttttttat agaatatatt tctcaatagc acgcgcaacg ccgtcttctt cgttgcttga
     8701 tgtaacggca tccgcaagag atttgacata atcgctggca tttcccattg caatcccaag
     8761 ccctgcaaac tggagcattt cgatatcgtt attagcatcg cccatggcca taatctctga
     8821 ggaatcaatc ttcaaaatct cagctagtcg tgaaagagca gtagcctttg tcgttccaag
     8881 cggcattgct tcataaatga caggctgcga acgaactcca ctgaatcgtt ggcaaagctc
     8941 ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt gttcctaaaa acataccttg
     9001 gaacatccgg aactttccac tagtcgcttc ttcaagagaa atttcagtca ggtctgaaaa
     9061 tactagttta gcatcatttt caataacttg attgggtttg ccaccgagaa caaaataatg
     9121 tgactcgtca aaaagtgtca actgaacatc actcttttca gcaaggtcat agaggtattc
     9181 gatgtcagct ggactcagtt cttgccagtc aaccaagccc cagtcgctag tctggtgagt
     9241 tgaacaaccg ttgttaacaa taatatattc gttctggagg tcaagctcca gttttttgta
     9301 gtaggggagg acaccgaaaa gggggcgacc cgtacagaga accagtttga cacctttttc
     9361 aatggctttg tgaatagcag taatgtgagc ttgtgggatt tccttggctt cattgaggag
     9421 ggtgccgtcc atatccaagg ctagtagttt aatcataggt cttccttctt tatcttttgc
     9481 tattattata gcatattttg gagaagaaat tgatagaaag cttgagacta attgatttta
     9541 tagtttaaga tgttttgatg acaattcatg atttgaagag gatatttcgc aaagatatgc
     9601 tatactatgt ttgtcaatgt tgcaactaga caaattaaaa aaccaactta atataatagt
     9661 ttttttgtaa gtaggtatga gtatcagatt actcaactaa tctgaagaat aatggaggaa
     9721 atatatcatg attttaatga caaaaaatat aaatctaaca aatgaagaat tagagctgat
     9781 acaaggtgga gcagattcat atggtaaaaa tcctaatggt aggtacgatt gggaaataga
     9841 accagtatta actctgccgg ttcatggatt ttgtcccaga ggcacctatg atttaggata
     9901 tattggagga ggcaatcatc tttgcaaagg aagtgctgcg agattttaag taaaatttat
     9961 tagtaatatg aagaaacaag gggagaaagc agagaattta atatgaaaaa acgggctatt
    10021 caaattttac tagcattgtc cttaattttt tacaaatcaa cttggttttg gagagttttc
    10081 aatcacctcg caaagcccta tctaccagca agtcgtgaat tttttcagat tctgcttttg
    10141 atggagagcg gagttctttt cttagcggtc atctatctac tggtttttgc aggaaagaaa
    10201 atttttcatt tcaagtggca gctgaggtac ttcatctacc ttttactggg ctacatcatt
    10261 tcatatatgt ctgacttcct cttttcgtat ttcatatccc tgtcttcaaa tcagatttct
    10321 ttgaatgaaa cggtagaaat gatggggaga caggagttcc cttatttctt gctcatcgtt
    10381 tgcttcatcg cccctattgc tgaggaattg atttatcgag gtgtgcttat gacaaccttt
    10441 ttcaaaaact caccttggta cggagatgtt ttgctttctg ctattatttt cggttatatt
    10501 catatcaatt ttgctttaac tcctcttgct tttttcattt atgctagtgg aggtcttatt
    10561 ttagctctat tgtatcgcat gactaaaaat ctctactatc caatactagt tcatattctc
    10621 atcaatatca ctgccttctg ggatgtttgg ttactcctat tttcaggaag ttagcttact
    10681 aaaaaaatgt cggaattttc cggcattttc ttttttcaca aatagtcaac gtttttcttt
    10741 ccgatactga agtggtgtgt agccacttat ttttttgaat tgattttgaa aataagattg
    10801 gcgtgagaaa ggcagatagt gaagatagtt aagaagaata ggatgttctt ttttcctttt
    10861 tggaaaactt ctaaaatatg gtataatgaa aagataaaga agttgggggt agaagatgaa
    10921 cattcaacaa ttacgctatg ttgtggctat tgccaatagt ggtacttttc gtgaagctgc
    10981 tgaaaagatg tatgttagtc agccgagtct gtctatttct gttcgtgatt tggaaaaaga
    11041 gttgggcttt aagattttcc gtcggaccag ctcagggact ttcttgaccc gtcgtgggat
    11101 ggaattttat gaaaaagcgc aagaattggt taaaggattt gatatttttc aaaatcagta
    11161 tgccaatcct gaagaagaaa aagatgaatt ttccgttgct agccagcact atgacttctt
    11221 accaccaact attacggcct tttcagagcg ctatcctgac tataagaact tccgtatttt
    11281 tgaatcaact actgttcaaa tattagatga agtggcgcaa gggcatagtg agattgggat
    11341 tatctacctc aacaatcaaa ataaaaaggg gattatgcaa cgggttgaaa agttaggtct
    11401 ggaggtcatc gaattgattc ctttccatac ccatatttat ctctgtgagg gtcatccttt
    11461 agcccagaaa gaggaattag tcatggagga tttagcggat ttaccaacgg ttcgtttcac
    11521 tcaagagaaa gacgagtacc tttattattc agagaacttt gttgatacca gcgctagctc
    11581 acagatgttt aatgtgacag accgtgccac cttgaatggt attttggagc ggacggacgc
    11641 ctatgcgaca ggttctggat ttttagatag tgacagtgtt aatggcatta cagttattcg
    11701 tctcaaggat aacctagata accgcatggt ctatgttaaa cgtgaagaag tggagcttag
    11761 tcaagctggg actctcttcg tagaagtcat gcaagaatat tttgatcaaa agaggaaatc
    11821 atgaaaaaaa gagcaatagt ggcagtcatt gtactgcttt tgattgggct ggatcagttg
    11881 gtcaaatcct atatcgtcca gcagattcca ctgggtgaag tgcgctcctg gatccccaat
    11941 ttcgttagct tgacctacct gcaaaatcga ggtgcagcct tttctatctt acaagatcag
    12001 cagttgttat tcgccgtcat tactctggtt gtcgtgatag gtgccatttg gtatttacat
    12061 aaacacatgg aggactcatt ctggatggtc ttgggtttga ctctaataat cgcgggtggt
    12121 cttggaaact ttattgacag ggtcagtcag ggctttgttg tggatatgtt ccaccttgac
    12181 tttatcaact ttgcaatttt caatgtggca gatagctatc tgacggttgg agtgattatt
    12241 ttattgattg caatactaaa agaggaaata aatggaaatt aaaattgaaa ctggtggtct
    12301 gcgtttggat aaggctttgt cagatttgtc agaattatca cgtagtctcg cgaatgaaca
    12361 aattaaatca ggccaggtct tggtcaatgg tcaagtcaag aaagctaaat acacagtcca
    12421 agagggtgat gtcgtcactt accatgtgcc agaaccagag gtattagagt atgtggctga
    12481 ggatcttccg ctagaaatag tctaccaaga tgaggatgtg gctgtcgtta acaaacctca
    12541 gggaatggtt gtgcacccga gtgctggtca taccagtgga accctagtaa atgccctcat
    12601 gtatcatatt aaggacttgt cgggtatcaa tggggttctg cgtccaggga ttgttcaccg
    12661 tattgataag gatacgtcag gtcttctcat gattgctaaa aacgatgatg cgcatctagc
    12721 acttgcccaa gaactcaagg ataaaaagtc tctccgcaaa tattgggcga ttgttcatgg
    12781 aaatctgcct aatgatcgtg gtgtaattga agcgccgatt ggccggagtg aaaaagaccg
    12841 taagaaacag gctgtaactg ctaaagggaa gcctgcagtg acgcgttttc acgtcttgga
    12901 acgctttggc gattatagct tagtagagtt gcaactggag acagggcgca ctcatcaaat
    12961 ccgtgtccac atggcttata tcggccatcc agtcgctggt gatgaggtct atggtcctcg
    13021 aaagactttg aaaggacatg gacaatttct tcatgccaag actttaggtt ttactcatcc
    13081 gagaacaggt aagaccttgg aatttaaagc agatatccca gagattttta aggaaacctt
    13141 ggagagattg agaaagtaag aatgaaaaag aaattaacta gtttagcact tgtaggcgct
    13201 tttttaggtt tgtcatggta tgggaatgtt caggctcaag aaagttcagg aaataaaatc
    13261 cactttatca atgttcaaga aggtggcagt gatgcgatta ttcttgaaag caatggacat
    13321 tttgccatgg tggatacagg agaagattat gatttcccag atggaagtga ttctcgctat
    13381 ccatggagag aaggaattga aacgtcttat aagcatgttc tgacagaccg tgtctttcgt
    13441 catttgaagg aattgggtgt ccaaaaactt gattttattt tggtgaccca tacccacagt
    13501 gatcatattg gaaatgttga tgaattactg tctacctatc cagttgaccg agtctatctt
    13561 aagaaatata gtgatagtcg tattactaat tctgaacgtc tatgggataa tctgtatggc
    13621 tatgataagg ttttacagac tgctgcagaa aaaggtgttt cagttattca aaatatcaca
    13681 caaggggatg ctcattttca gtttggggat atggatattg agctctataa ttatgaaaat
    13741 gaaactgatt catcgggtga attaaagaaa atttgggatg acaattccaa ttccttgatt
    13801 agcgtggtga aagtcaatgg caagaaaatt taccttgggg gcgatttaga taatgttcat
    13861 ggagcagaag acaagtatgg tcctctcatt ggaaaagttg atttgatgaa gtttaatcat
    13921 caccatgata ccaataaatc aaataccaag gatttcatta aaaatttgag tccgagtttg
    13981 attgttcaaa cttcggatag tctaccttgg aaaaatggtg ttgatagtga gtatgttaat
    14041 tggctcaaag aacgaggaat tgagagaatc aacgcagcca gcaaagacta tgatgcgaca
    14101 gtttttgata ttcgaaaaga cggttttgtc aatatttcaa catcctacaa gcctattcca
    14161 agttttcaag ctggttggca taagagttca tatggaaact ggtggtatca agcgcctgat
    14221 tctacaggag aatatgctgt cggttggaat gaaattaagg gtgaatggta ttactttaac
    14281 caaacgggta tcttattaca gaatcaatgg aaaaaatgga acaatcattg gttctatttg
    14341 acagactctg gtgttgctgc taaaaattgg aagaaaatcg ctggaatctg gtattatttt
    14401 aacaaagaaa accagatgga aattggttgg attcaagata aagagcagtg gtattatttg
    14461 gatgttgatg gctctatgaa gacaggttgg cttcaatata aggggcaatg gtattacttt
    14521 gctccatcag gggaaatgaa aacgggctgg gtaaaagata aagaagcctg gtactatatg
    14581 gattctactg gtatcatgaa gacaggtgag atagaagttg ctggacatca ttactatcta
    14641 gaagaatcag gagctatgaa gcaaggctgg cttaaaaagg caaatgattg gtatttctac
    14701 aagacagatg gttcacgagc tataggttgg attaaagaga aggataaatg gtacttcttg
    14761 aaagaaaatg gtcaattact tgtgaatggt aagacaccag aaggctatac tgtggattca
    14821 agtggtgcct ggttagtgga tgttccgatc gagaaatctg ctacaattaa aactacaagt
    14881 cattcagaaa taaaagaatc caaagaagta gtgaaaaagg atcttgaaaa taaagaaacg
    14941 agtcaacatg aaagtgttac aaattcttca actagtcaag atttgacatc ctcaacttca
    15001 caaagctctg aaacgagtgt aaacaaatcg gaatcagaac agtagtagaa aagaaggttt
    15061 tagggccttc tttttcctat caactctttt ctatttcctg ttattcatgt tataatggat
    15121 aaatatgaat aatcggagtg agactatgaa atacaaacgg attgtcttta aggtgggtac
    15181 ttcttctctg acaaatgagg atggaagttt atcacgtagt aaggtaaagg atattaccca
    15241 gcagttggct atgctgcacg aggctggtca tgagttgatt ttggtgtctt caggtgccat
    15301 tgcggctggt tttggagcct taggatttaa aaagcgtccg actaaaattg ctgataaaca
    15361 ggcttcagca gcggtagggc agggactttt gttggaagaa tatacgacca atcttctctt
    15421 gcgtcaaatc gtttctgcac aaatcttgct gacccaagat gactttgtgg ataagcgtcg
    15481 ttataaaaat gcccatcagg ctttgtcggt tttgctcaac cgtggggcaa ttcctatcat
    15541 caatgagaat gatagtgtcg ttattgatga gctcaaggtt ggggacaatg acactctaag
    15601 tgctcaagta gcggcgatgg tccaagcaga ccttttagtt ttcttgacag atgtggacgg
    15661 tctctatact ggaaatccta attcagatcc aagagccaaa cgcttggaga gaatcgagac
    15721 catcaatcgt gagattattg atatggctgg tggagcaggt tcgtcaaacg gaactggggg
    15781 tatgttaacc aaaatcaagg ctgcaactat cgcgacggaa tcaggagttc ctgtttatat
    15841 ctgctcatcc ttgaaatcag attccatgat tgaggcggca gaggagaccg aggatggttc
    15901 ttactttgtt gctcaagaga aggggcttcg tacccagaaa caatggcttg ccttctatgc
    15961 tcagagtcaa ggttctattt gggttgataa aggggctgcg gaagctctct ctcaacatgg
    16021 aaagagtctt ctcttatctg gtatcgttga agcagaagga gccttttctt acggtgatat
    16081 cgtgacagta tttgacaagg aaagtggaaa atcacttgga aaaggacgcg tgcaatttgg
    16141 agcatctgct ttggaggata tgttgcgttc tcaaaaagcc aagggtgtct tgatttaccg
    16201 tgacgactgg atttccatta ctcctgaaat ccaactactt tttacagaat tttagaggta
    16261 aactatggtg agtagacaag aacaatttga acaggtacag gctgttaaaa aatcgattaa
    16321 cacagctagt gaagaagtga aaaaccaagc cttgctagcc atggctgatc acttagtggc
    16381 tgctactgag gaaattttag cggctaatgc cctcgatatg gcagcggcta aggggaaaat
    16441 ctcagatgtg atgttggatc gtctttattt ggatgcagat cgtatagaag cgatggcaag
    16501 aggaattcgt gaagtggttg ccttaccaga tccaatcggt gaagttttag aaacaagtca
    16561 gcttgaaaat ggtttggtta tcacaaaaaa acgtgtagct atgggtgtca tcggtattat
    16621 ctatgaaagc cgtccaaatg tgacgtctga tgcggctgct ttgactctta agagtggaaa
    16681 tgcggttgtt cttcgtagtg gtaaggatgc ctatcaaaca acccatgcca ttgtcacagc
    16741 cttgaagaag ggcttggaga cgactactat tcatccaaat gtgattcaac tggtggagga
    16801 tactagccgt gaaagtagtt atgctatgat gaaggccaag ggctatctag accttctcat
    16861 tcctcgtgga ggagctggct tgatcaatgc agtggttgag aatgcgattg tacctgttat
    16921 cgagacaggg actgggattg tccatgtcta tgtggataag gatgcagacg aagacaaggc
    16981 gctgtctatc atcaacaatg ctaaaaccag tcgtccttct gtttgtaatg ccatggagat
    17041 tctgctggtt catgaaaaca aggcagcaag catccttcct cgcttggatc aaatgctggt
    17101 tgcagagcgt aaggaagctg gactggaacc aattcaattc cgcttggata gcaaagcaag
    17161 ccagtttgtt tcaggtcaag cagctgagac ccaagacttt gacaccgagt ttttagacta
    17221 tgtccttgct gttaaggttg tgagcagttt agaagaagcg gttgcgcaca ttgaatccca
    17281 cagcacccat cattcggatg ctattgtgac ggaaaatgct gaagctgcag catactttac
    17341 agatcaagtg gactctgcag cggtgtatgt taatgcctca actcgtttca cagatggagg
    17401 acaatttggt cttggttgtg aaatggggat ttctactcag aaattgcacg cgcgtggtcc
    17461 aatgggcttg aaagagttga ccagctacaa gtatgtggtt gctggtgatg ggcagataag
    17521 ggagtaagag atgaagattg gatttatcgg tttggggaat atgggtgcta gcttggcaaa
    17581 atctgtcttg cagactagga cgtcagatga gattctcctt gccaatcgta gtcaagctaa
    17641 ggtagatgct ttcattgcag actttggtgg tcaggcttcc agcaatgaag aaatgtttgc
    17701 agaagcagat gtgatttttc taggagttaa gcctgctcag ttttctgaac tgctttctca
    17761 ataccagacc atccttgaaa aaagagaaag tcttcttttg atttcgatgg cagctggatt
    17821 gaccttagaa aaactagcaa gtcttatccc aagtcaacac cgaattattc gtatgatgcc
    17881 taatacccct gcttctatcg ggcaaggagt gattagttat gccttgtctc ctaattgcag
    17941 ggctgaggac agtgagctct tttgtcagct tttatccaag gctggtctct tggttgaatt
    18001 aggagaaagc ttaatcaatg cagcgacagg tcttgcaggc tgtggaccag cctttgtcta
    18061 tctctttatt gaagccttgg cagatgcagg tgttcagacg ggattatcac gagaaacagc
    18121 cttgaaaatg gcagcccaaa ctgtggtagg agctgggcaa ttggtcctag aaagccagca
    18181 acatcctgga gttttgaaag atcaagtttg tagtccaggc ggttcgacta ttgctggcgt
    18241 agcaagccta gaagcgcatg cttttcgagg cacagtcatg gaggcagttc atcaagccta
    18301 taaacgaaca caagaactag gtaaataaga ggtagtttta tctgcctctt ttatggtggt
    18361 tgatactctt cgaaaatcaa attcaaactg cgtcagcttc accttgccgt actcaagtac
    18421 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtatgaa atgagaagac
    18481 aaaaagattg tcacaaaccc ctattttttt gatagaatag aagtagtaaa aaagaaatga
    18541 gttagacatg tcaaaaggat ttttagtctc tcttgaggga ccagagggag caggcaagac
    18601 cagtgtttta gaggctctgc taccaatttt agaggaaaaa ggagtagagg tgctgacgac
    18661 ccgtgaacct ggcggagtct tgattgggga gaagattcgg gaagtgattt tggatccaag
    18721 tcatactcag atggatgcta aaacagagct acttctctat attgccagtc gcagacagca
    18781 tttggtggaa aaagttcttc cagcccttga agctggcaag ttggtcatca tggatcgttt
    18841 tatcgatagt tctgttgcct atcagggatt tggtcgtggc ttagatattg aagccattga
    18901 ctggctcaat cagtttgcga cagatggcct caaacccgat ttgacactct attttgacat
    18961 cgaggtggaa gaaggactgg ctcgtattgc tgctaatagt gaccgcgagg ttaatcgttt
    19021 ggatttggaa gggttggact tgcataaaaa agttcgtcaa ggctaccttt ctcttctgga
    19081 taaagaggga aatcgcattg tcaagattga tgctagtctc cctttggagc aagttgtgga
    19141 aactaccaag gctgtcttgt ttgacggaat gggcttggcc aaatgaaaca agatcaacta
    19201 aaggcttggc aaccagctca gtttgaccgt tttgtccgta tcttagaaca agaccagctc
    19261 aatcacgcct atctcttttc aggtttcttt ggaagcttgg aaatagcgca atttttagct
    19321 aagagcctct tttgtacgga taaagttggc gtcttaccat gtgagaaatg ccgaagttgc
    19381 aagctgattg aacaggaaga gtttccagat gtcaccttga ttaagccagt caatcaggtc
    19441 atcaagacag aacgcattcg ggaattggtg ggacagtttt ctcaagcagg gattgaaagc
    19501 cagcaacagg tctttatcat cgagcaagcg gataaaatgc atcccaacgc agccaattct
    19561 ctgctcaagg tcatcgaaga accccagagt gaagtttata ttttcttctt gactagcgat
    19621 gaggaaaaga tgttaccgac aatccgaagt cggactcaga tcttccactt taaaaagcaa
    19681 gaagaaaaac ttatcttact cttagaacaa atgggacttg ttaagaaaaa agcgactctt
    19741 ttagctaagt ttagtcaatc gcgagctgaa gcagaaaagt tggctaatca ggcaagtttt
    19801 tggaccttgg tcgatgaaag tgaacgcctg ctgacttggt tagtagctaa gaaaaaagaa
    19861 agttatctac aggttgccaa attagccaac ttggcagatg ataaggaaaa acaggatcag
    19921 gttttacgga ttcttgaagt tctctgtggg caggacctct tgcaggtaag agtaagagtg
    19981 attctacaag atttactaga agctagaaaa atgtggcaag ctaatgtcag ctttcaaaat
    20041 gccatggaat atctggtctt gaaagaaata taaactcaaa aatgaatgat aaagaaagga
    20101 aagggctgtt ttatggacaa aaaagaatta tttgacgcgc tggatgattt ttcccaacag
    20161 ttattggtaa ccttggccga tgtggaagcc atcaagaaaa atctcaagag cctggtagag
    20221 gaaaatacag ctcttcgttt ggaaaattct aagttgcgag aacgcttggg tgaggtggaa
    20281 gcagatgctc ctgtcaaggc caagcatgtt cgtgaaagtg tccgtcgcat ttaccgtgat
    20341 ggatttcacg tatgtaatga tttttatgga caacgtcgag agcaggacga agaatgtatg
    20401 ttctgtgatg agttgttata cagggagtag gcatgcaaat tcaaaaaagt tttaaggggc
    20461 agtctcccta tggcaagctg tatctagtgg caacgccgat tggcaatcta gatgatatga
    20521 cttttcgtgc tatccagacc ttgaaagaag tggactggat tgctgctgag gatacgcgca
    20581 atacaggtct tttgctcaag cattttgaca tttccaccaa gcagatcagt tttcatgagc
    20641 acaatgccaa ggaaaaaatt cctgatttga ttggtttctt gaaagcaggg caaagtattg
    20701 ctcaggtctc tgatgccggt ttgcctagca tttcagaccc tggtcatgat ttggttaagg
    20761 cagctattga ggaagaaatt gcagttgtta cagttccagg tgcctctgca ggaatttccg
    20821 ccttgattgc cagtggttta gcgccgcagc cacatatctt ttacggcttt ttaccgagaa
    20881 aatcaggcca gcaaaagcaa tttttcgact cgaaaaaaga ctatcctgaa actcagattt
    20941 tttatgaatc gccccatcgt gtggcagata cattggaaaa tatgctagaa gtctacggtg
    21001 accgctccgt tgtcttggtc agggaattga ccaaaatcta tgaagaatac caaagaggta
    21061 caatttctga attgctggaa agcattgctg aaacgtctct caagggtgaa tgtcttctga
    21121 ttgttgaagg tgccagtcag gatgtggaag aaaaagacga ggaagacttg ttcttagaaa
    21181 tccaagctcg tatccagcaa ggtatgaaga aaaatcaagc tattaaggaa gtagctaaga
    21241 tttaccagtg gaataagagt caactctacg ctgcctacca cgactgggaa gaaaaacaat
    21301 aaagggagac aggatgtaat aattctgtct gtttctgttt aacttaatta gtgatgataa
    21361 tataaagatg tatcacttgg tatagaagct ttggtattaa gttttttatt aagcccatac
    21421 ggaataccga tggttggagc agcagttata gcgttcttag aaggtataaa tagaaaaata
    21481 aggtcatttt aaatcaaagg attgataaat cagaaagaag gtgatttttt gcgaacatac
    21541 gaaaataaag aagaactaaa agctgagata gagaaaacat ttgagaaata tattttagaa
    21601 tttgataata ttccagaaaa tttaaaagat aagagagctg atgaagttga cagaactcca
    21661 gcagaaaacc ttgcttatca ggttggttgg accaacttgg ttcttaaatg ggaagaagat
    21721 gaaagaaagg ggcttcaagt aaaaacacca tcggataaat ttaaatggaa tcaacttggt
    21781 gaattatatc agtggttcac agatacctac gctcatttat ctctgcaaga gttgaaagca
    21841 aaattaaatg aaaatattca ttctatctct gcaatgattg attcgttgag tgaggaagaa
    21901 ttatttgaac cgcatatgag aaagtgggct gatgaagcga ctaaaacagc gacttgggaa
    21961 gtgtataagt ttattcatgt aaatacggtt gcaccttttg gaactttcag aactaaaatc
    22021 agaaaatgga agaagatagt attataaatt atatttttaa ctttaaaaaa tttcataaaa
    22081 atggttacca aaggcgatag aagaaaaact atcgtctttt tctttgcaaa tttttaagaa
    22141 gggaggtgat cttgcatgga ctttgaatat ttttataaca gagaagcgga aagatttaac
    22201 ttcttaaaag taccggagat attagttgat agagaagaat ttcggggctt atcagcagaa
    22261 gcaattatcc tttattccat acttcttaaa cagacaggaa tgtcatttaa gaataactgg
    22321 atagacaagg aaggcagagt atttatctat tttactgtcg aagaaattat gaaaagaaga
    22381 aatatctcaa agccaactgc cataaaaaca ttagatgagc ttgatgtaaa aaaaggaata
    22441 ggactgatcg aaagagtaag gcttggactt ggtaagccga acatcattta tgttaaagac
    22501 tttatgagta tatttcaggt aaaagaaaat gacttacaga agtcaaaaaa cttaacttca
    22561 gaagtaaaag attttaacct cagaagtaaa gaaaatgaac ttcaagaggt taagaacctt
    22621 gactctaact atatagagaa taataagagt aagtatagta agagagaata tagttttggt
    22681 gaaaacggac ttggaacatt tcaaaatgtg tttttagctg ctgaagatat atcggattta
    22741 caaatcataa tgaactcaca gcttgagaat tacattagac ttcctgcaaa actagaatcc
    22801 tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc gtttacgatg
    22861 atttcgatag gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac
    22921 cttgcttctc tccttagata gcgcatggtt acaggcttta tcttcagctg ttagcggctt
    22981 gagtttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata
    23041 accactgtcg gccaagattt taccagcttg tccgatattt ctgcaactca ttttgaacaa
    23101 cttcatatca tgactatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt
    23161 gacaatcgct tgagccttca tagcgtgaaa tttcttttta ccagaatgat tcgctaattg
    23221 tttttttagg gcgattgatt tgtacttccg tcgcatcaat cattaccgtg tcctcagaac
    23281 tgagaggagt tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc
    23341 tccgacggat taagttgctt tcgtgaatac caaaatcagc cgcaatttct tcataagttc
    23401 gatattctcg cacatataga agagtggcca taagaaggtc ttctaggctt aatttaggtt
    23461 ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt aatacagcta atatctcttc
    23521 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
    23581 tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt ctattggaaa
    23641 gtaagaaata ttgaagctga ggctattaga agaaattgtg agcgtggtgc tattttttca
    23701 ggtaaaataa aatatcacga agattcacag tttaaaggag atcactatgt tgaatgttat
    23761 gctgttttag ataatacggt tatagcaaga gatagaataa cagtccctat cgatccgtta
    23821 tgtggaaaag attttataga gtagcatata attgattctt aactggaata ctcactatct
    23881 ctttacatca agaaaatgac taaacaggga agtttgcctt cttccctttt tttgttatac
    23941 tagtagaaga aaaaatagaa agatttgtgg gagtgaaaaa gtcctgtgga ctttttcagc
    24001 ctgagccaag aaactcgaaa tctcgtaagt ctgattggct ttttcaatgt gaatcttaac
    24061 ttcacactcc caaagaggta ttagtgtcgt gtctcaatct tatatcaatg ttatcggtgc
    24121 tggtttggca ggttctgaag cagcttacca aatcgcagag cgtggtattc cagttaaact
    24181 ttatgaaatg cgtggtgtca agtcgactcc tcagcacaaa acagacaatt ttgctgagtt
    24241 ggtttgttcc aattctttgc gtggggatgc tttgacaaat gcagttggtc ttctcaagga
    24301 agaaatgcgt cgcttgggtt ctgttatctt ggaatctgct gaggctacac gtgttcctgc
    24361 cggtggagcc cttgcggtgg atcgtgatgg tttctctcaa atggtgaccg aaaaagtggt
    24421 caaccacccc ttgattgaag tggtgcgtga tgaaattaca gaattgccaa cagatgttat
    24481 tacagttgtg gcgactggtc ccttgactag cgatgccctg gctgaaaaga ttcatgccct
    24541 taataatggc gatggcttct atttctacga tgcagcagcg cctattatcg atgtcaacac
    24601 tatcgatatg agtaaggtct atctcaaatc tcgttatgat aagggagaag cagcctatct
    24661 caatgctcca atgaccaagc aagagtttat ggatttccat gaagccttgg tcaatgcgga
    24721 agaagcaccg ctcaattctt ttgaaaaaga aaagtacttt gaaggatgta tgccaatcga
    24781 agttatggcc aaacgtggca ttaaaactat gctttatggc cctatgaagc cagtcggtct
    24841 tgagtatccg gacgactaca caggacctcg tgatggagaa tttaaaacac cttatgcggt
    24901 tgtgcaactt cgtcaggata atgcagctgg tagcctctac aatattgttg gtttccagac
    24961 ccacctcaaa tggggagaac aaaagcgtgt cttccaaatg attccgggtc ttgaaaatgc
    25021 ggagtttgtc cgttatggtg tcatgcatcg caattcttac atggattcac caaatcttct
    25081 tgagcagact taccgttcta agaaacaacc aaatctcttc tttgctggtc agatgacggg
    25141 tgtggaaggc tatgttgagt cggcggcttc aggcttagtt gcgggaatta acgcagctcg
    25201 tctcttcaag gaagaaagcg aggctatttt ccccgagacg acagcgattg gaagcttagc
    25261 tcattacatt acccatgccg acagcaaaca tttccaacca atgaatgtca attttgggat
    25321 catcaaggag ttggaaggcg agcgtatccg tgataagaag gctcgttatg aaaaaattgc
    25381 agagcgtgcc cttgccgact tagaggaatt tttgactgtc taattttttt gaaagaattg
    25441 ctcatgatac tataaaaatc ttagaaattg tgataaaata ggtaggatga aagaaggaga
    25501 gtgaaaatgg cgaatcccaa gtataaacgt attttaatca agttatcagg tgaagccctt
    25561 gccggtgaac gtggcgtagg gattgatatc caaacagttc aaacaatcgc aaaagagatt
    25621 caagaagttc atagcttagg tatcgaaatt gcccttgtta tcggtggagg aaatctctgg
    25681 cgtggagaac ctgcagcaga agcaggtatg gaccgtgttc aggcagatta cactggaatg
    25741 cttgggactg ttatgaatgc tcttgtgatg gcagattcat tgcaacaagt tggggttgat
    25801 acacgtgttc aaacagctat tgccatgcaa caagtggcag agccttatgt acgtggacgt
    25861 gctcttcgcc accttgaaaa aggccgtatc gttatctttg gtgctggaat tggttcacct
    25921 tacttctcaa ccgatacaac agcggctctt cgttcagctg aaatcgaagc ggatgccatt
    25981 cttatggcta aaaatggtgt cgatggtgtg tacaatgccg atcctaagaa agataagaca
    26041 gctgttaagt ttgaagaatt gacccaccgt gacgttatca ataaaggtct tcgtatcatg
    26101 gactcaacag cttcaaccct ctcaatggac aacgacattg acttggttgt cttcaacatg
    26161 aaccaatcag gcaacatcaa acgtgtcgta tttggtgaaa atatcggaac aacagtttca
    26221 aataatatcg aagaaaagga ataagaaaga atatggctaa cgcaattatt gaaaaagcta
    26281 aagagagaat gacccagtct caccaatcac ttgctcgtga atttggtggt atccgtgctg
    26341 gccgtgccaa tgcaagcttg cttgaccgtg tacatgtaga atactatgga gtcgaaactc
    26401 ctcttaatca aatcgcttca attacgattc cagaagcgcg tgttttgttg gtaacaccat
    26461 ttgacaagtc ttcattgaaa gacatcgaac gtgccttgaa cgcttctgat cttggtatca
    26521 caccggctaa tgacggttct gtgattcgct tggttatccc agctcttaca gaagaaactc
    26581 gtcgtgacct tgctaaagaa gtgaagaagg tcggcgaaaa tgctaaagtg gctgtccgca
    26641 atatccgtcg cgatgctatg gacgaagcta agaaacaaga aaaagcaaaa gaaatcactg
    26701 aagacgaatt gaagactctt gaaaaagaca ttcaaaaagt aacagacgat gctgttaaac
    26761 acatcgacga tatgactgcc aacaaagaga aagaactttt ggaagtctaa aaataaacag
    26821 aaaaactcag ttggcattgc tggctgagtt ttattcgaaa gaaggaaata tgaatacaaa
    26881 tcttgcaagt tttatcgttg gactgatcat cgatgaaaat gaccgttttt actttgtgca
    26941 aaaggatggt caaacctatg ctcttgctaa ggaagaaggt caacatacag taggggatac
    27001 ggtcaaaggt tttgcataca cggatatgaa gcaaaaactc cgcctgacaa ccttagaagt
    27061 gactgccact caggaccaat ttggttgggg atgtgtcaca gaggttcgta aggacttggg
    27121 tgtctttgtg gatacaggcc ttcctgacaa ggaaatcgtt gtgtcactcg atattctccc
    27181 tgagttcaag gaactctggc ctaagaaggg cgaccaactc tacatccgtc ttgaagtgga
    27241 taagaaagac cgtatctggg gcctcttggc ttatcaagaa gacttccaac gtctcgctcg
    27301 tcctgcctac aacaacatgc agaaccaaaa ctggccagcc attgtttacc gtctcaagct
    27361 gtcaggaact tttgtttacc taccagaaaa taatatgctt ggttttattc atcctagcga
    27421 gcgttacgca gagccacgtt tggggcaagt attagatgcg cgcgttattg gtttccgtga
    27481 agtggaccgc actttgaacc tctccctcaa accacgctcc tttgaaatgt tggaaaacga
    27541 tgctcagatg attttgactt atttggaaag caatggcggt ttcatgacct taaatgacaa
    27601 gtcatctcca gacgacatca aggcaacctt tggcatttct aaaggtcagt tcaagaaagc
    27661 tttaggtggt cttatgaagg ctggtaaaat caagcaggac cagtttggga cagagttgat
    27721 ttagggaggt ttatgagaaa atcattttac acttggctca tgaccgagcg caatcctaaa
    27781 agtaacagtc ccaaagcaat tttggcagac ctcgcttttg aagaggcagc ttttccaaaa
    27841 catacagatg attttgatga ggtcagtcgc tttttggagg agcatgccag tttctctttt
    27901 aacctaggag attttgacag catttggcag gaatatctag aacactagca tttattcatt
    27961 gggtttgggc tagtaatttc tccatccctc tgctataata aaaagaaata aaaggattag
    28021 agaggttctt tatttgaagg aacattcaat agacattcaa ctgagtcatc cagatgacct
    28081 gtttcatctt tttggttcca atgagcgcca tcttcgtttg atggaagaag agctggatgt
    28141 ggtgattcat gctcgtacgg agattgtcca ggttttggga gaagagtctg cttgtgagga
    28201 agcccgtcag gttattcaag ctctcatggt cttggtgaac cgtgggatga ccgttggtac
    28261 gccagatgta gtgacggcta ttagtatggt caaaaacgat gaaattgata agtttgtcgc
    28321 cctttacgaa gaagaaatta tcaaggataa tactgggaaa ccgatccgcg tcaaaacctt
    28381 aggtcaaaaa ctttatgtgg acagtgtcaa acagcatgat gtgacctttg gaattgggcc
    28441 tgcagggacg gggaagacct ttcttgcagt tactttggca gtgactgccc ttaaacgtgg
    28501 gcaagtcaag cggattatct tgacacgtcc agcggtggaa gcaggagaga gtctaggttt
    28561 tcttccgggt gatcttaagg agaaggtaga tccttacctt cgtcctgttt acgatgcctt
    28621 gtatcagatt ctggggaaag accaaacgac tcgtctcatg gagcgtgaaa ttatcgaaat
    28681 tgcgcccctt gcctatatgc gtggccggac cttggatgat gcctttgtca ttctcgatga
    28741 ggcgcaaaac acgaccatca tgcagatgaa gatgttcttg acgcgtttag gctttcattc
    28801 taagatgatt gtcaatggag atatcagtca gattgacctg ccacgtaatg tcaagtccgg
    28861 tttgattgat gctcaagaga aactcaagaa catccatcag attgactttg ttcatttttc
    28921 agccaaggat gtggttcgcc atccagttgt cgctcagatt atccgagcct atgaatattc
    28981 tactgaagtt gcacacgact gattttgagg aagttcgcct gcaaaagaat atacttttga
    29041 gagaggaaaa tccagttgta taggctaaag gttttatcca aaggtctgag acaacgatta
    29101 ggcacgatgg aaagaacttt tatgtggctg atgacgatca gtgcatcttc ctgtgtcata
    29161 atcacagggc acaagaaagt aggaatttga aaagatgatt gaccaactat ctaagtatta
    29221 cagttgtagg atactaactg aaaaggatat tccaagtatt ttatctttat atgaaagtaa
    29281 tcctctgtat tttcagcatt gtccaccaga gccaaatttt gcaactgtaa aagaggacat
    29341 gctttgtcta cctgaaggta aagctaaggc tgataagttt tttgttggat tttggaatgg
    29401 atctgacctt gtggctgtta tggattttgt ctatgcatat cctgatgagg agactgtttt
    29461 tattggtttg tttatggttg atcaagccta tcagagaaaa gggattggta gtcatattgt
    29521 gacagaagca ctagcttatt ttgctaagaa ctttcgaaag gcacgtttgg cttatgttaa
    29581 gggaaatccg caatctcagc atttttggga aaagcagggc tttaaatcaa ttggatgcga
    29641 ggttaagcaa gaactctata cggttgttat cgctgaacag agcctagaag attagaaatg
    29701 gcatcaagta agaactattt ggaatttgtt ttggaacaat tatcaggatt agatgatgtg
    29761 acttaccgtt ccatgatggg ggagtatatt ctttacttcc gcggcaagat tattggcggc
    29821 atttatgacg atcgcttttt agttaaaccc gtgcaagcag tcttagataa gattgaccaa
    29881 tcttcttttg agtttccata caaaggtgcc aaagaaatga tttgagtgga agaacttgat
    29941 aataagatgt ttctataaga cctgatttta gctatgtata accaactgcc aacgcccaaa
    30001 cctaaaaaga aaaagcaagg gtgaacgaag taaaaaagaa gtctgctaag gccctgtctt
    30061 tgcacgggta aaattttata tataaaaaga agctgggact aaagagctca gcttcctttg
    30121 gtttatataa ttgtcattac aagacgaagt ggttgggcga aactctgttg actttattca
    30181 atttagagtt tcttatgcac aattgagtct ggaacgaaag tctccagttg caaagtatac
    30241 agtacaataa accaacgatg taatagctga tgacacaaag cacagtgggt aggacttgcg
    30301 aagtcaccct tttcttttca aaatttatac taaatcattg atatcagtgt agtcacgatt
    30361 aagtccttga gcaactggta ggttagtcaa gtaaccttga taagtagtca caccttgacg
    30421 caagccttca tcttcagaga ttgcttgtgc gaatcctttg ccagccaaag cttcgatata
    30481 aggaagagtg acattggtta gggcgatggt tgaagtgcga gcaaccgcac cagggatatt
    30541 ggcaacggca tagtggagaa caccgtgttt ttcatagacg ggttcatcgt gcgttgtcac
    30601 acggtcagct gtttcgataa cgccaccttg gtcaacagca acgtcaacga tacagagcct
    30661 ggacgcattt gtttgaccat ctcatctgtc accaattccg gtgcttttgc accagggatg
    30721 agaatggctc caatcaccac atcagcatct ctcacacttg cttcaatgtt gaatgaatta
    30781 gacataagag tttgaatttg acttccaaag acttcttcta gaactgagag acgcttggca
    30841 ctaatatcta aaatagtcac ttgagcacca agaccaaggg cgatgcgggc agcatgtgta
    30901 ccgacgacac catcaccgat gatagttact tttccttttg gaacacctgg tacaccacca
    30961 agtagaacac cagagccacc agcttgctta gtaaggaagt gagctccgat ttaaacagcc
    31021 atacgacctg caacctcact cataggaacg aggagcggta gttgtccttg attgtcacga
    31081 acagtttcat aggcaattcc tgttgttttt gctgctaaca tagcatctgc taattctgga
    31141 gcagcggcca tgtgcaagta ggtgaagaga agaagatcgt cgcgcaagta accgtattca
    31201 gaacttaaag gttcttttac tttcacaacc aactctgctg cccaagcttc accagcagta
    31261 gcgacaatct cagctccttg cttttgatag tcagcatcag taaagccaga accgagacca
    31321 gcatttgttt cgataaggac acgatgacca cgactaacta agctatgaac acctgcaggt
    31381 gtgagggcga cacggttttc gttattttta atttcttttg ggattccgat taacattgag
    31441 ataacctacc tttcaattga cggtcttgtt ttggttgtca cattccagtt cataaatcaa
    31501 aaatgtgacg gtttcattgt atatgaaacc gcttcaaaaa tcaagaaaaa cttgtcatcc
    31561 caattttttt atgctagact agtgaaaatc aagctctaat ggagggaaaa gtatggaatc
    31621 aatttttgta aaacttgccc agtatccgtc tatagaaacg gagcgtttat tgcttagacc
    31681 tgtaactttg gatgatgcgg aagcaatgtt tgactatgcc tcggacaagg gtaatacacg
    31741 ttacactttt ccaaccaatc aaagcttgga agaaaccaag aataacattg ctcagttcta
    31801 cttggctaat cccttgggac gttggggaat agaactaaaa agcaatggca aatttatcgg
    31861 aacaattgat ttgcacaaga ttgatcctgt tcttaagaag gtagctattg gttatattat
    31921 caaccaaacg tattggaatc aaggattaac gacagaaacc aatcgtgctg tgattgagct
    31981 agcttttgag aagataggaa tgaataagtt agttgcttta tacgataagg ctaatcccgc
    32041 atcaggaaag gtcatggaga aatcaggaat gcgtttttcc catgcagaac catatgcttg
    32101 tatggaccag catgaaaaag gccgaatcgt gacaagagtt cattatgtct tgaccaagga
    32161 agactatttt gcaaataaat aagcagttga aaagaaattt ttcgactgtt ttttcttcct
    32221 cttacgaata atctaagaga ggagaaaata tggaagcaat tatcgagaaa atcaaagagt
    32281 ataaaatcat cgtcatctgt actggtctgg gcttgcttgt aggaggattt ttcctgctaa
    32341 aaccagctcc acaaacacct gtcaaagaga cgaatttgca ggctgaagtc gcagctgttt
    32401 ccaaggattt ggtatccgaa gaggaagtga acaaggaaga aaaggaagaa ccccttgaac
    32461 aagatctaat cacagtagat gtcaaaggtg ctgtcaaatc gccagggatt tatgacttgc
    32521 ctgtaggtag tcgagtcaat gatgctgttc agaaggctgg tggcttgaca gagcaagcag
    32581 acagcaagtc gctcaatcta gctcagaaag ttagtgatga ggctctggtt tacgttccta
    32641 ctaagggaga agaagcagtt agccaacaga ctggtttggg gacagcttct tcaataagca
    32701 aggaaaagaa ggtcaatctc aacaaggcca gtctggaaga actcaagcag gtcaagggac
    32761 tgggaggaaa acgagctcag gacattatcg accatcgtga ggcaaatggc aagttcaagt
    32821 cagtagacga gctcaagaag gtctctggca ttggtggcaa aacaatagaa aagcttaaag
    32881 actatgttac agtggattaa gaatttctct attcccctaa tttacctgag ttttctatta
    32941 ctttggcttt attacgctat tttctcagca tcttatcttg ctttgttggg ctttgttttt
    33001 ctgctagtct gtctctttat ccaatttccg tggaaatctg ctggtaaagt tctaataatt
    33061 tgcggaatct ttggattttg gtttgttttt caaaattggc aacagagtca agcgagtcaa
    33121 aatctggcgg attctgttga aagggtacgg attttacctg atactattaa ggttaatggt
    33181 gatagtctat cctttcgtgg caagtctaac ggtcgtgctt tccaagtcta ttataaactc
    33241 cagtccgagg aggagaaaga agcctttcaa gctttaaccg acctgcatga gataggacta
    33301 gaagggaagc tttcggagcc agaagggcag agaaattttg gtggctttaa ttaccaagcc
    33361 tatctgaaga ctcagggaat ttaccagact ctcaatatca aaaaaatcca gtcacttcaa
    33421 aagattggca gttgggatat aggagaaaac ttgtccagtt tacgtcgaaa ggctgtggtt
    33481 tggattaaga cgcactttcc agaccctatg cgcaattaca tgacaggact cttgctggga
    33541 catctggaca ccgactttga ggagatgagt gagctttatt ccagtctagg aattatccac
    33601 ctctttgccc tatctggcat gcaggtaggt tttttcatga atggatttaa gaaacttctc
    33661 ttgcgattgg gcttgaccca agaaaagttg aaatggctga cttatccctt ttcccttatc
    33721 tatgcgggac taactggatt ttcagcatcg gttattcgca gtctcttgca aaagctactg
    33781 gctcaacatg gggttaaggg cttggataat tttgccttga cggtgcttgt cctctttatt
    33841 gtcatgccaa actttttctt gacagcagga ggagtcttgt cctgcgctta tgcttttatc
    33901 ctgaccatga ccagcaaaga agggaagggg ctcaaggctg ttgctagtga aagtctagtc
    33961 atctccttgg gcatattgcc cattctatcc ttctattttg cggaatttca accttggtct
    34021 atccttttga cctttgtctt ttcctttcta tttgacttga ccttcttacc gctcttgtct
    34081 attttatttg tcctttcctt tctctatcca gtcattcagc tgaactttat ctttgaatgg
    34141 ttggagggca ttattcgctt ggtctcacag gtgacaagta ggcctctagt ctttggacaa
    34201 cccaacgcat ggcttttaat cttattgtta atttctttgg ctttggtcta tgatttgagg
    34261 aaaaacatta aaggattaac agtattgagt ttattgatta caggtctctt tttcttgacc
    34321 aagtatccac tggaaaatga aatcaccatg ctggatgtgg ggcaaggaga aagtattttc
    34381 ctacgggatg taactgggaa aaccattctc atagatgtag gtggtaaggc agaatcttat
    34441 aagaaaatcg aaaaatggca agaaaagatg acgaccagca atgcccagcg aaccttgatt
    34501 ccctatctca aaagtcgagg agtagctaag attgaccagc taattttgac taacacggac
    34561 aaggagcatg ttggagattt gtcagaggtg accaaggctt tccatgtagg ggagattcta
    34621 gtatcaaaag acagtctgaa acagaaggaa tttgtggcag aactacaggt gactcaaaca
    34681 aaggtgcgta gtatgacagt aggggagtac ttgcccattt tcggaagtca gttagaagtc
    34741 ctatctccaa gggaaattgg atatggaggt catgaagatt ccctggttct ttatgggaaa
    34801 ctcttgaata atcactttct cttcatagga aatttggagg agaaaggaga gaaggacttg
    34861 ctgaagtact atccagactt gaaagtaaat gttttgaaag ctagccaaca tggcaataaa
    34921 aaatcatcaa gtccagcctt tctagaaaaa ctcaaaccag agcttactct tatctcagtt
    34981 ggaaagagca atcgaatgaa actcccccat caggaaacat tgacacgact ggaaggtatc
    35041 aatagcaaag tttaccgaac tgaccagcaa ggagctatac gctttaaggg gttggatagt
    35101 tggaaaatcg aaagtgttcg ataggaagga taaatgttgt agattagtga aataaactaa
    35161 aaatttgttg cataataatg ataaaaatgg tataatgaaa acgtattcaa tattgaggat
    35221 ataaaatcat taaaaattag caaaaatcgt ttaattagtt agtttatgat tattggtctt
    35281 tttcagtcca gtatatctgc tgtgacagtc actaaaagtt acaagtatga ttggaatacg
    35341 gtttgggaat atagtaccaa ctatcacgac catcagtatg cttggattcc gtcatggtct
    35401 cgttatgaca gctattctga gtatccagtt ggttctggct ggaactacgg tcgttatgag
    35461 gtcataaact attacagcgg aggctattaa tccttaaaga gtgagaaaag gagggctgga
    35521 tatgttaaat cttactcatg ttaccttaaa aacgcgacaa gtcatcttgc aagatgcgga
    35581 ttttaccttt aaaaagggta ggatttatgg ccttcttgct atcaatggct cgggaaagac
    35641 gaccctgttc cgtgccatta gcaatttaat tcccataagt agtggaaata tcgcagcccc
    35701 tccttcttta ttttattatg agagtattga atggctggat ggaaacttaa gtgggatgga
    35761 ctaccttcgt cttatcaaaa acatctggaa gtcaggtctg aacttgaggg atgaaatcgc
    35821 ctattgggaa atgtctgatt atatcagcct tcccattcgc aagtattcct taggcatgaa
    35881 gcaacgcttg gtgattgcca tgtatttcct cagtcaggcc aaatgctggc tcatggatga
    35941 gattacaaat ggcttagatg agtattatcg acagaagttt tttgataggc tagcacaaat
    36001 cgatagacaa gaacagctgg ttcttttaag ttcccactat aaggaagagt tggttgatgt
    36061 ctgcgataga gtagtaacca ttcatcaggg gcagatagaa gaggtttagt ttatgaaaga
    36121 tgttagtcta tttttattga aaaaagtttt caaaagtcgt ttaaactgga ttatcttact
    36181 tttatttgca tctgtactcg gtgttacctt ttatttaaat agtcagactg caaactcaca
    36241 cagcttggag agcaggttgg aaagtcgcat tgcagccaac gagagggcta tcaatgaaaa
    36301 tgaagagaaa ctctcccaaa tgtctgatac cagctcggag gaataccagt ttgctaaaaa
    36361 taatttagac gtgcaaaaaa atcttttgac gcgaaagaca gaaattctaa ctttactaaa
    36421 agaagggcgc tggaaagaag cctactatct gcagtggcaa gatgaagaga agaattatga
    36481 atttgtatca aatgacccga ctgctatctc tggcttaaaa atgggggttg accgcgaacg
    36541 gaagatttac caagccctgt atcccttgaa cataaaagca catactttgg agtttccgac
    36601 ccacgggatt gatcagattg tctggatttt agaggttatc atcccaagct tgtttgtggt
    36661 tgcgattatt tttatgctaa cacaactatt tgcagaaaga tatcaaaatc atctggacac
    36721 agctcactta tatcctgttt caaaagtgac atttgcaata tcctctcttg gagttggagt
    36781 gggatatgta actgtgctgt ttatcggaat ctgtggcttt tcttttctag tgggaagtct
    36841 gataagtggt tttggacagt tagattatcc ctacccaatt tatagcttag tgaatcaaga
    36901 agtaactatt gggaaaatac aagatgtatt atttcctggc ttgctcttag ctttcttagc
    36961 ctttatcgtc attgtggaag ttgtgtactt gattgcttac tttttcaagc aaaaaatgcc
    37021 tgtcctcttt ctttcactca ttgggattgt tggcttattg tttggcatcc aaacaattca
    37081 gcctcttcaa aggattgcac atctgattcc ctttacttac ttgcgttcag tggagatttt
    37141 atctggaaga ttatctaagc agattgataa tgtcgatcta aattggagca tggggatggt
    37201 cttacttcct tgcctgatta tctttttgct agtggggatt ctatttatcg aaaactgggg
    37261 aagttcacgt aaaaaggaag tttttaatag gtcttagcat tcttataagg aagttaagga
    37321 aaaactaaca tagagaggga atcaacttga ttctctcttt ttaattcgaa aaccaaaata
    37381 caaacacaaa cttttcaaaa aataactttt tatcttgaca agagctagaa aacttggtat
    37441 catataaaag ttgagaaaag cagaagtgag agcttctcgc cttgtgacat taagttgcct
    37501 ggccctacgg atgaaaagtt tcgaagaaac gctatcataa cgtgcgggct tgtatattta
    37561 cgagtccgct attgtttttc tctaataaaa caaaagaggt gaaaaccata gcaaagcaag
    37621 acttattcat caatgatgag attcgtgtac gtgaagttcg cttgattggt cttgaaggag
    37681 aacagctagg catcaagcca ctcagtgaag cgcaagcttt ggctgataac gctaatgttg
    37741 acctagtatt gattcaaccc caagccaaac cgcctgttgc aaaaattatg gactacggta
    37801 agttcaaatt tgagtaccag aagaagcaaa aagaacaacg taaaaaacaa agcgttgtta
    37861 ctgtgaaaga agttcgtcta agtccaacaa ttgacaaggg tgactttgat acaaaacttc
    37921 gtaatgcacg taagttcctt gaaaaaggaa ataaagttaa ggtatctatt cgctttaagg
    37981 gtcgtatgat tacccataaa gagattggtg caaaagtttt agccgagttt gctgaagcaa
    38041 ctcaagatat tgccatcatc gaacaacgtg ctaaaatgga tggacgtcaa atgttcatgc
    38101 aattggcgcc agcgactgac aaaaaataat tgtcagaaag ttaaataaag gagaaaaaat
    38161 catgccaaaa caaaaaacac accgcgcatc agctaaacgt ttcaaacgta caggttctgg
    38221 tggacttaaa cgtttccgtg cttacacttc tcaccgtttc cacggaaaaa ctaagaaaca
    38281 acgtcgtcat cttcgtaaag catctatggt gcattcagga gattacaaac gtatcaaagc
    38341 aatgcttact cgcttgaaat aatagcttga ctgtaagtaa acaattctag gaaatatttg
    38401 gaggaaataa aacatggcac gtgttaaagg tggcgttgta tcacgcaaac gtcgtaaacg
    38461 tattcttaaa ttagcaaaag gttactatgg agctaaacac atcttgttcc gtactgcaaa
    38521 agaacaagta atgaactctt actactatgc ataccgtgac cgtcgtcaga aaaaacgtga
    38581 cttccgcaaa ttgtggatta ctcgtatcaa tgcggcagct cgtatgaacg gactttcata
    38641 ctcacaattg atgcatggtt tgaaattggc tgagatcgaa gttaaccgta aaatgcttgc
    38701 tgacttggct gttaacgatg cagtagcttt cacagctctt gcagatgcag ctaaagcaaa
    38761 acttggtaaa taacaactga tgagactgga acaggattgt ccagtctttt taaaaataaa
    38821 ggagaaagat atggcttcaa aaatgctaca cacttgctta cgagtagaaa atcttgaaaa
    38881 atcaatcgca ttttatcaag atgcttttgg ttttaaagaa ttgcgtcgca gagattttcc
    38941 agaccatgcc ttcacgattg tctatctagg tcttgagggt gatgattatg agttggagtt
    39001 gacttataac tacgatcacg gtccgtatgt ggttggtgat gggtttgccc atatcgccct
    39061 cagtacacct gatcttgagg cacttcatca agaacacagt gcaaaaggct atgaagtgac
    39121 tgagccaaat ggtctaccag gaactacacc aaactattac tttgttaaag accctgatgg
    39181 atataaggtc gaagtcattc gtgaaaaata atttcgtgca agttaagtag aatattcgtt
    39241 ttctacttga ctttttttag ctgaaagagt atactaataa aaattcaacc tttaagggga
    39301 gtccagagag actcacaagg tgtcagataa aagaatagtg caattttcta gaggagacct
    39361 tttgagtgtg ctctcttgtg ttgtacgatt ttaactgagg ccttgcacta gcaaggtctt
    39421 ttctttatct ggtcccctta aaatttaagg aggaaaagtt atgaatctca catgtaagaa
    39481 gcgtttgggt gtcattcggt tggaaaccat gaaggtggtt gcacaagagg aaatcgcgcc
    39541 agcaatcttt gaattagtcc tagaaggaga aatggttgaa gccatgcgag caggccaatt
    39601 tcttcatctg cgtgtaccag acgatgccca tctcttacgt cgtcctattt caatttcgtc
    39661 tattgacaag gcaaacaagc agtgtcacct catttatcgg attgagggag ctgggactgc
    39721 aattttttca accttaagtc agggagacac tcttgatgtg atggggcctc agggaaatgg
    39781 ttttgacttg tctgaccttg atgagcagaa tcaggttctc cttgttggtg gtgggattgg
    39841 tgttccaccc ttgcttgagg tggccaagga attgcatgaa cgtggagtga aagtagtgac
    39901 agtcctcggt tttgctaata aggatgctgt tattttgaaa acggaattgg ctcagtatgg
    39961 tcaggtcttt gtaacgacag atgatggttc ttatggcatc aagggaaatg tttccgttgt
    40021 tatcaatgat ttagatagtc agtttgatgc tgtttactcg tgtggggctc caggaatgat
    40081 gaagtatatc aatcaaacct ttgatgatca cccaagagcc tatttatctc tggaatctcg
    40141 tatggcttgt gggatgggag cttgctatgc ctgtgttcta aaagtaccag aaagcgagac
    40201 ggtcagccaa cgcgtctgtg aagatggtcc tgttttccgc acaggaacag ttgtattata
    40261 aggagaaaat tatgactaca aatcgattac aagtgtccct acctggtttg gatttgaaaa
    40321 atccgattat tccagcatca ggctgttttg gctttggaca agagtatgcc aagtactatg
    40381 atttaaacct tttaggttct attatgatca aggcgacaac ccttgaacca cgttttggga
    40441 acccaactcc aagagtagca gagacgcctg ctggtatgct caatgcaatt ggcttgcaaa
    40501 atcctggttt agaggttgtt ttggctgaaa agttaccttg gctggaaaga gaatatccaa
    40561 atcttcctat tattgccaat gtagctggtt tttcaaaaca agagtatgca gctgtttctc
    40621 atgggatttc caaggcaact aatgtaaaag ctatcgagct caatatttct tgtcccaatg
    40681 ttgaccactg taatcatgga cttttgattg gtcaagatcc agatttggct tatgatgtgg
    40741 tgaaagcagc tgtggaagcc tcagaagtgc cagtttatgt caaattaacc ccgagtgtga
    40801 ccgatatcgt tactgtcgca aaagctgcag aagatgcggg agcaagtggc ttgaccatga
    40861 tcaatactct ggttggaatg cgctttgacc tcaaaaccag aaaaccaatc ttggccaatg
    40921 gaacaggtgg aatgtcaggt ccagcagtct ttccagtagc cctcaaactc atccgccaag
    40981 tagcccaaac aacagacctg cctatcattg gaatgggggg agtggattcg gctgaagctg
    41041 ccctagaaat gtatctggct ggggcatctg ctatcggagt tggaacagct aactttacca
    41101 atccttatgc ctgccctgac atcatcgaaa atttaccaaa agtcatggat aaatacggta
    41161 ttagcagtct ggaagaactc cgtcaggaag taaaagagtc tctgaggtaa actacaatca
    41221 atctgttctt gattttttat tagtttgtaa tatgaattta ggagaatttt ggtacaataa
    41281 aataaataag aacagaggaa gaaggttaat gaagaaagta agatttattt ttttagctct
    41341 gctatttttc ttagctagtc cagagggtgc aatggctagt gatggtactt ggcaaggaaa
    41401 acagtatctg aaagaagatg gcagtcaagc agcgaatgag tgggtttttg atactcatta
    41461 tcaatcttgg ttctatataa aagcagatgc taactatgct gaaaatgaat ggctaaagca
    41521 aggtgacgac tattttcacc tcaaatctgg tggctatatg gccaaatcag aatgggtaga
    41581 agacaaggga gccttttatt atcttgacca agatggaaag atgaaaagaa atgcttgggt
    41641 aggaacttcc tatgttggtg caacaggtgc caaagtaata gaagactggg tctatgattc
    41701 tcaatacgat gcttggtttt atatcaaagc agatggacag cacgcagaga aagaatggct
    41761 ccaaattaaa gggaaggact attatttcaa atccggtggt tatctactga caagtcagtg
    41821 gattaatcaa gcttatgtga atgctagtgg tgccaaagta cagcaaggtt ggctttttga
    41881 caaacaatac caatcttggt tttacatcaa agaaaatgga aactatgctg ataaagaatg
    41941 gattttcgag aatggtcact attattatct aaaatccggt ggctacatgg cagccaatga
    42001 atggatttgg gataaggaat cttggtttta tctcaaattt gatgggaaaa tagctgaaaa
    42061 agaatgggtc tacgattctc atagtcaagc ttggtactac ttcaaatccg gtggctacat
    42121 ggcagccaat gaatggattt gggataagga atcttggttt tacctcaagt ttgatggcaa
    42181 aatggctgaa aaagaatggg tctacgattc tcatagtcaa gcctggtact acttcaaatc
    42241 cggtggttac atgacagcca atgaatggat ttgggataag gaatcttggt tttatctcaa
    42301 atctgatggg aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcttggta
    42361 ctacttcaaa tccggtggtt acatgacagc caatgaatgg atttgggata aggaatcttg
    42421 gttttacctc aagtctgatg gcaaaatggc tgaaaaagaa tgggtctacg attctcatag
    42481 tcaagcctgg tactacttca aatctggtgg ctacatggcg aaaaatgaga cagtagatgg
    42541 ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa gctacaaatg aaaatgctgc
    42601 ttactatcaa gtagtgcctg ttacagccaa tgtttatgat tcagatggtg aaaagctttc
    42661 ctatatatcg caaggtagtg tcgtatggct agataaggat agaaaaagtg atgacaagcg
    42721 cttggctatt actatttctg gtttgtcagg ctatatgaaa acagaagatt tacaagcgct
    42781 agatgctagt aaggacttta tcccttatta tgagagtgat ggccaccgtt tttatcacta
    42841 tgtggctcag aatgctagta tcccagtagc ttctcatctt tctgatatgg aagtaggcaa
    42901 gaaatattat tcggcagatg gcctgcattt tgatggtttt aagcttgaga atcccttcct
    42961 tttcaaagat ttaacagagg ctacaaacta cagtgctgaa gaattggata aggtatttag
    43021 tttgctaaac attaacaata gccttttgga gaacaagggc gctactttta aggaagccga
    43081 agaacattac catatcaatg ccctttatct ccttgcccat agtgccctag aaagtaactg
    43141 gggaagaagt aaaattgcca aagataagaa taatttcttt ggcattacag cctatgatac
    43201 gaccccttac ctttctgcca agacatttga tgatgtggat aagggaattt taggtgcaac
    43261 caagtggatt aaggaaaatt atatcgatag gggaagaact ttccttggaa acaaggcttc
    43321 tggtatgaat gtggaatatg cttcagaccc ttattggggc gaaaaaattg ctagtgtgat
    43381 gatgaaaatc aatgagaagc taggtggcaa agattagtac tataagtgaa tatgatttga
    43441 gtgaatagta agttaaaaat cctgatttca agtaaaatca ggattttttc atggatgcaa
    43501 tttttttgga gtctggtgtg acgcggaggg tcttttgtcc tgtgtaagtg acaaagccgg
    43561 gttttccacc agttggttta ttgagttttt tgacttcaat catatctacc tgcaccagat
    43621 tcgacaggcg cccttgagag aagtaggcag ctaactctgc tgcgtctgtc ttgactgcat
    43681 cagatgggtc aagatttcct gagatgacaa catggcttcc aggaatgtcc ttagcatgga
    43741 accaaagttc ctccttgcgg gccattttaa aggtcaattc ctcattttga agattgtttc
    43801 gtccgacata gatgatggtt ttgccatcgc ttgctagata ttgttctagt tttttgcgtt
    43861 tctggatttt ctcccgttgt cttctgcgga taaaacctgt ttgaatcaat tcttcacgga
    43921 tttcagcgat ttcttccagt ccagcttggt tgaggacggt ttctacactt tccagataga
    43981 gaatagtggc tttggtttct tcaatcaaat cagtcaagta tttgacagct tctttgagtt
    44041 tctgataccg tttaaaatag cgttgggcat tctggttggg agtcagagcc ttatcaagcg
    44101 caatcatgat aggttggttg gtatagtagt tgtctaggat aacctggtct tggtcgttag
    44161 gcacttggtg taggaaggtt gtcagcaatt ctcctttttg acgaaattct tcagcgttgt
    44221 ctgtcgccag taactctttt tcctgttttt tgagtttgtg tcggtttttc tgaagttcat
    44281 tttcaacacg acgaatcagt tcactggcct gctgtttgac gcggtcgcgc tcagccttat
    44341 ccttatagta ggtgtccaac aaatcagaaa gatttgcaaa aggctctccc acctgatttg
    44401 caaaaggaac tggactgaag gaagtctcag tcaagcatgg cttggtttct tgattgaaaa
    44461 aatttcggaa agcggaaagt ttttcactaa ccagtatcct ttccaattca tttgccgtat
    44521 cgcgtcccag accttgaaag aggctttgaa gattttttgc tgttagttct tgggtttgca
    44581 ggatttcaaa gagcttttca tccttgatag taaaaggatt gagagattct gtacttggcg
    44641 gagcgatata ggtcgatcct ggaagtaagg tgcggtagct attttgtgaa aaaccgacgt
    44701 gtttgataac ttcgaggatt ttatgactgc ttttatcgac cagtagaata ttactgtgtt
    44761 tccccataat ttcaataatc aaggtagcct ggatatggtc tccaatctcg tttttattgg
    44821 aaactgtcat ttccacaata cggtcatttt ccacttgctc aatcgactca atcagggccc
    44881 cctgcaaata ctttctcaaa accatgataa aggtagaagg ttgagctgga ttttcaaaag
    44941 tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc agaaaggagc aggcgatggc
    45001 tttggcgatt gctgcggatt tgcaagacca actcttgttc aaaaggctga ttgattttct
    45061 ggatgcgacc attcactaat tcgcttcgca attcctcaac tatgtggtgt aaaaaaaatc
    45121 catcaaatga catcgttctc tccttgtgat tgtattccat agtattatat caaaaaggta
    45181 gaataaaatc atggaaatgt ggtataataa agccaagtaa agagaaatga gaagcacatg
    45241 tatattgaaa tggtagatga aactggtcaa gtttcaaaag aaatgttgca acaaacccaa
    45301 gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag acaaggagat ggcagtcact
    45361 tttgtgacca atgagcgtag tcatgaactt aatctggagt accgtgacac cgaccgtccg
    45421 acagatgtca tcagccttga gtataaacca gaattggaaa ttgcctttga cgaagaggat
    45481 ttgcttgaaa atccagaatt ggcagagatg atgtctgagt ttgatgccta tattggggaa
    45541 ttgttcatct ctatcgataa ggctcatgag caggccgaag aatatggtca cagctttgag
    45601 cgtgagatgg gcttcttggc agtacacggc tttttacata ttaacggcta tgatcactac
    45661 actccggaag aagaagcgga gatgttcggt ttacaagaag aaattttgac agcctatgga
    45721 ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg atatccagtt tagaatttgc
    45781 catcacaggg atttttactg ctatcaagga agaacgaaat atgcgaaaac atgcagtgac
    45841 ggctctagtg gtcatccttg caggttttgt ttttcaggtg tcacgaatcg aatggctctt
    45901 tctcctattg agcattttct tggtagtagc ctttgagatt atcaattctg ctatcgaaaa
    45961 tgtggtggat ttggccagtc actatcactt ttccatgctg gctaaaaatg ccaaggatat
    46021 ggcggctggc gcggtattag tggtttctct tttcgcagcc ttaacaggtg cattgatttt
    46081 tctcccacga atctgggatt tattatttta aacagtaaga ggaaattatg acttttaaat
    46141 caggctttgt agccatttta ggacgtccca atgttgggaa gtcaaccttt ttaaatcacg
    46201 ttatggggca aaagattgcc atcatgagtg acaaggcgca gacaacgcgc aataaaatca
    46261 tgggaattta cacgactgat aaggagcaaa ttgtctttat cgacacacca gggattcaca
    46321 aacctaaaac agctctcgga gatttcatgg ttgagtctgc ctacagtacc cttcgcgaag
    46381 tggacaccgt tcttttcatg gtgcctgctg atgaagcgcg tggtaagggg gacgatatga
    46441 ttatcgagcg tctcaaggct gccaaggttc ctgtgatttt ggtggtgaat aaaatcgata
    46501 aggtccatcc agaccagctc ttgtctcaga ttgatgactt ccgtaatcaa atggacttta
    46561 aggaaattgt tccaatctca gcccttcagg gaaataacgt gtctcgtcta gtggatattt
    46621 tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc tgatcaaatc acagaccatc
    46681 cagaacgttt cttagtttca gaaatggttc gcgagaaagt attgcaccta actcgtgaag
    46741 agattccgca ttctgtagca gtagttgttg actctatgaa acgagacgaa gagacagaca
    46801 aggttcacat ccgtgcaacc atcatggtcg agcgcgatag ccaaaaaggg attatcatcg
    46861 gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc ccgtcgtgat atcgaactca
    46921 tgctaggaga caaggtcttc ctagaaacct gggtcaaggt caagaaaaac tggcgcgata
    46981 aaaagctaga tttggctgac tttggctata atgaaagaga atactaagta gaggtaggct
    47041 catgcctgct tcttgttttt acagaaggag gacttatgcc tgaattacct gaggttgaaa
    47101 ccgtttgtcg tggcttagaa aaattgatta taggaaagaa gatttcgagt atagaaattc
    47161 gctaccccaa gatgattaag acggatttgg aagagtttca aagggaattg cctagtcaga
    47221 ttatcgagtc aatgggacgt cgtggaaaat atttgctttt ttatctgaca gacaaggtct
    47281 tgatttccca tttgcggatg gagggcaagt atttttacta tccagaccaa ggacctgaac
    47341 gcaagcatgc ccatgttttc tttcattttg aagatggtgg cacgcttgtt tatgaggatg
    47401 ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct tttagacgcc tactttattt
    47461 ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga tttacaggtc tttcaagctg
    47521 cccttgccaa gtccaaaaag cctatcaaat cccatctcct agaccagacc ttggtagctg
    47581 gacttggcaa tatctatgtg gatgaggttc tctggcgagc tcaggttcat ccagctagac
    47641 cttcccagag tttgacagca gaagaagcga ctgccattca tgaccagacc attgctgttt
    47701 tgggccaggc tgttgaaaaa ggcggttcca ccattcggac ctataccaat gcctttgggg
    47761 aagatggaag catgcaggat tttcatcagg tctatgataa gactggtcaa gaatgtgtac
    47821 gctgtggtac catcattgag aaaattcaac taggcggacg aggcacccac ttttgtccaa
    47881 actgtcaaag gagggactga tgagaaaaat catcggaatc actgggggaa ttgcctctgg
    47941 taagtcaact gtgacaaatt ttctaagaca gcaaggcttt caagtagtgg atgccgacgc
    48001 agtcgtccac caactacaga aacctggtgg tcgtctgttt gaggctctag tacagcactt
    48061 tgggcaagaa atcattcttg aaaacggaga actcaatcgc cctctcctag ctagtctcat
    48121 cttttcaaat cctgaagagc aaaaatggtc taagcaaatt caaggggaga ttatccgtga
    48181 ggaactggct actttgagag aacagttggc tcagacagaa gagattttct tcatggatat
    48241 tcccctactt tttgagcagg actacagcga ttggtttgct gagacttggt tggtctatgt
    48301 ggaccgagat gcccaagtag aacgcttaat gaaaagggac cagttgtcca aagatgaagc
    48361 tgagtctcgt ctggcagccc agtggccttt agaaaaaaag aaagatttgg ccagccaggt
    48421 tcttgataat aatggcaatc agaaccagct tcttaatcaa gtgcatatcc ttcttgaggg
    48481 aggtaggcaa gatgacagag attaactgga aggataatct gcgcattgcc tggtttggta
    48541 attttctgac aggagccagt atttctttgg ttgtaccttt tatgcccatc ttcgtggaaa
    48601 atctaggtgt agggagtgag caagtcgctt tttatgcagg cttagcaatt tctgtctctg
    48661 ctatttccgc ggcgctcttt tctcctattt ggggtattct tgctgacaaa tacggccgaa
    48721 aacccatgat gattcgggca ggtcttgcta tgactatcac tatgggaggc ttggcctttg
    48781 tcccaaatat ctattggtta atctttcttc gtttactaaa cggtgtattt gcaggttttg
    48841 ttcctaatgc aacggcactg atagccagtc aggttccaaa ggagaaatca ggctctgcct
    48901 taggtacttt gtctacaggc gtagttgcag gtactctaac tggtcccttt attggtggct
    48961 ttatcgcaga attatttggc attcgtacag ttttcttact ggttggtagt tttctatttt
    49021 tagctgctat tttgactatt tgctttatca aggaagattt tcaaccagta gccaaggaaa
    49081 aggctattcc aacaaaggaa ttgtttactt cagttaaata tccctatctt ttgctcaatc
    49141 tctttttaac cagttttgtc atccaatttt cagctcaatc gattggccct attttggctc
    49201 tttatgtacg cgacttaggg cagacagaga atcttctttt tgtctctggt ttgattgtgt
    49261 ccagtatggg cttttccagc atgatgagtg caggagtcat gggcaagcta ggtgacaagg
    49321 tgggcaatca tcgtctcttg gttgtcgccc agttttattc agtcatcatc tatctcctct
    49381 gtgccaatgc ctctagcccc cttcaactag gactctatcg tttcctcttt ggattgggaa
    49441 ccggtgcctt gattcccggg gttaatgccc tactcagcaa aatgactccc aaagccggca
    49501 tttcgagggt ctttgccttc aatcaggtat tcttttatct gggaggtgtt gttggtccca
    49561 tggcaggttc tgcagtagca ggtcaatttg gctactatgc tgtcttttat gcgacaagcc
    49621 tttgtgttgc ctttagttgt ctctttaacc tgattcaatt tcgaacatta ttaaaagtaa
    49681 aggaaatcta gtgcgagtaa aaattaatct caaatgctcc tcttgtggca gtatcaatta
    49741 cctaaccagt aaaaattcaa aaacccatcc agacaagatt gaggttttaa agtattgtcc
    49801 caaggaaaga aaagtaaccc tacatcttga atctaagtag attttatggt aaaataatag
    49861 ggattttaag gagtttgata tgtataacct attattaacc attttattag tattatctgt
    49921 tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac caatccagca atgtatttga
    49981 tgccagttca ggtgatttgt ttgaacgcag taaagctcgc ggttttgaag ctgtaatgca
    50041 gcgtttgaca gggattttag tctttttctg gctagccatt gccttagcat tgacggtatt
    50101 atcaagtaga taagaaaata atgggcagga ctaggtcttt gcctcttttt atttttaaag
    50161 gatgtttgag aaggttttac agtaaaagaa aattaaaaaa tctagaaaga aaatatgaaa
    50221 gatagaataa aagaatattt acaagacaag ggaaaggtga ctgttaatga tttggctcag
    50281 gctttgggaa aagacagttc caaggatttt cgtgagttga ttaaaacctt gtccttaatg
    50341 gaaagaaagc accagattcg ctttgaagaa gatggcagtc tgaccttgga agccaagaaa
    50401 aaacatgaga ttaccctcaa ggggattttt catgcccata aaaatggttt tggctttgtc
    50461 agcctagaag gggaagagga cgaccttttt gtagggaaaa atgatgtcaa ctatgctatt
    50521 gatggtgata ccgttgaggt cgtcatcaag aaagtcgctg accgcaataa gggaacagca
    50581 gcagaagcca aaattattga tatcctagaa cacagtttaa caacagttgt cgggcaaatc
    50641 gttctggatc agggaaagcc taagtatgtt ggctatattc gttcaaaaaa tcagaaaatt
    50701 agtcaaccga tttatgttaa gaaaccagcc ctaaaattag aaggaacaga agttctcaaa
    50761 gtctttatcg ataaatatcc aagcaagaaa catgatttct ttgtcgcgag tgttctcgat
    50821 gtggtgggac actcaacgga tgtcggaatt gatgttcttg aggtcttgga atcaatggac
    50881 attgtatccg agtttccaga agctgttgtt aaggaagcag aaagtgtgcc tgatgctccg
    50941 tctcaaaagg atatggaagg ccgtctggat ctaagagatg aaattacctt taccattgac
    51001 ggtgcggatg ccaaggactt ggacgatgca gtgcatatca aggctctgaa aaatggcaat
    51061 ttggagcttg gggttcacat cgcagatgtt tcttattatg tgaccgaggt gtctgccctt
    51121 gacaaggaag cccttaaccg tgcgacttct gtttacgtga cagaccgagt ggtgccaatg
    51181 cttccagaac gactatcaaa tggcatctgc tctctcaatc cccaagttga ccgcctgacc
    51241 cagtctgcta ttatggagat tgataaacat ggtcgtgtgg tcaactatac cattacacaa
    51301 acagttatca agaccagttt tcgtatgacc tatagcgatg tcaatgatat cctagctggc
    51361 gatgaagaaa agagaaaaga atatcataaa attgtatcaa gtatcgaact catggccaag
    51421 cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag ctctcaattt tgataccaat
    51481 gaagcgaaga ttttagtgga taaacaaggt aagcctgttg atatcgttct tcggcagcgt
    51541 ggcattgccg agcggatgat tgagtctttt atgttgatgg ctaatgaaac agttgccgaa
    51601 catttcagca agttggattt gccttttatc tatcgaattc acgaggagcc taaggctgaa
    51661 aaggttcaga agtttattga ttatgcttcg agttttggct tgcgtattta tgggactgcc
    51721 agtgagatta gtcaggaggc acttcaagac atcatgcgtg ctgttgaggg agaaccttat
    51781 gcagatgtat tgtccatgat gcttcttcgc tctatgcagc aggctcgtta ttcggagcac
    51841 aatcacggcc actatggact agctgctgac tattatactc actttaccag tccaattcgt
    51901 cgttatccag accttcttgt tcaccgtatg attcgggatt acggccgttc taaggaaata
    51961 gcagagcatt ttgaacaagt gattccagag attgcgaccc agtcttccaa ccgtgaacgt
    52021 cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa aggctgagta tatggaagaa
    52081 tacgtgggtg aagagtatga tgcagttgta tcaagtattg tcaaattcgg tctctttgtc
    52141 gaattgccaa acacagttga aggcttgatt cacatcacta atctacctga attttatcat
    52201 ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag gtatcacttt ccgagtgggt
    52261 cagcagatcc gtatccgtgt tgaaagagcg gataaaatga ctggagagat tgatttttca
    52321 ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga aacagtctag tcgtagtggc
    52381 agagggcgtg gttcaaatcg tcgttcggat aagaaggaag acaagagaaa atcaggacgc
    52441 tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga aaaaaggaaa gaaacctttt
    52501 tacaaggaag tagctaagaa aggagccaag catggcaaag ggcgagggaa aggtcgtcgc
    52561 acaaaataaa aaggcacgcc acgactatac aatcgtagat acgctagagg cagggatggt
    52621 cctgactgga actgaaatca agagtgtacg agctgctcga attaatctca aggatggctt
    52681 tgctcaagtg aaaaatggag aagtttggct gagcaatgtt catatcgcgc cttacgaaga
    52741 gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa ctcctgctct ataaaaagca
    52801 aattcaaaaa ttggaacaag agaccaaagg gacaggaatg accttagttc cccttaaggt
    52861 ctatataaaa gatggctacg ctaagcttct tttaggactt gccaaaggga agcatgacta
    52921 tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga gatatcgcgc gtgtgatgaa
    52981 agctgttaat cagcgataaa aagaggaatt gaaaatggaa aaattagttg cctataagcg
    53041 catgcctttg tggaataaac aaacaatgcc tgaagctgtt cagcaaaagc acaatacaaa
    53101 agttgggact tgggggaaaa ttactgtctt gaagggagct atcaagttta ttgaattgac
    53161 agaagaaggg gaagttctag ctgaacacct ctttgaagca ggggcagaca atccaatggc
    53221 ccaacctcaa gcctggcacc gagtggaagc tgccacagat gatgtggaat ggtacttgga
    53281 attttattgt aaacctgagg attattttgc taaaaaatac aataccaatc ctgttcattc
    53341 agaggtccta gaggccatgc agacagtgaa acaagggaaa gctttggatt tgggttgtgg
    53401 tcaggggcgt aattctcttt ttctagccca gcaagatttt gatgtgacgg ctgtagatca
    53461 aaatggacta gctcttgaaa tcttgcaaag cattgtggag caggaagatt tggacatgcc
    53521 tgttggcctt tacgatatca attcagctag cattgaacaa gaatatgatt ttatcgtttc
    53581 aacagttgtt ctcatgtttc tacaagcgga ccgcattcca gctattattc aaaatatgca
    53641 ggagaaaacc agtgttggtg gttacaacct tatcgtttgt gccatggaca cggaggatta
    53701 tccttgctcg gttaacttcc cattcacctt taaagaagga gaactggcag actattacaa
    53761 ggattgggaa ttggttaagt acaatgaaaa tccaggccat ttgcatcgtc gcgatgagaa
    53821 tggcaatcgt attcaactac gctttgcgac cttactagct aagaaaatca agtaaacaca
    53881 catgaagatt aggaattttc ctgatctttt ttctttttta cgaatgatat agaaaaggag
    53941 ggaattcatg tttgttgcga gagatgctag gggagaattg gtaaatgtgt tagaggataa
    54001 acttgagaag caagcataca cctgcccagc ttgtggaggc cagctccatt tgcgtcaagg
    54061 accaagtgta cggacgcatt ttgcccataa atccttaaaa gactgtgatt ttttctttga
    54121 aaatgaaagt ccagaacacc tggccaataa ggaatccctc tatcactggt tgaaaaaaga
    54181 gacaaaggtt caattagagt acccgctttc agaacttaaa cagattgcgg atgtatttgt
    54241 aaatggcaat ctagatctag aagttcagtg tagtcccttg cctcagaaag tccttaaaga
    54301 gcgaagtgag ggatatcgta gtcagggtta ccaagtactg tggttgctgg gtcaaaaact
    54361 gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt ctttatttca gtcaaaacat
    54421 gggcttttat gtttgggaat tagacaagga aaaacaagtt ttaagactca aatacctgat
    54481 ttaccaggat ctccgcggta aactccatta tcaaatcaag gaattttcct atggtcaagg
    54541 tagtttattg gaaatattgc gtcttcccta taagagacaa aaaatatctc attttacagt
    54601 ttctgaggac aaggacatct gtcgctatat ccggcaacaa ctttattatc aaaatctctt
    54661 ttggatgaaa gaacaagcag aagcctatca aaagggagaa aatatcctga cttatggact
    54721 gaaagaatgg tatccacaaa ttcgaccaat agtgggcaaa tttttccaga ttgaacaaga
    54781 cttgactaac tattatcagc acttttatac ctattaccaa aaaaatcctc aaaatgattg
    54841 gcaaaagctt tatccaccag ccttttatca gcaatatttc ttgaaaaata tggtaaaata
    54901 gaaaggatgg aggaatctaa tggtattaca aagaaatgaa ataaatgaaa aagatacatg
    54961 ggatctatca acgatctacc caactgacca ggcttgggaa gaagccttaa aagatttaac
    55021 agaacaattg gagacagtag cccagtatga aggccatctc ttggatagtg cggataacct
    55081 actagaaatc actgaatttt ctcttgaaat ggaacgccag atggagaagc tttacgttta
    55141 tgctcatatg aagaatgacc aggatacacg tgaagctaag tatcaagagt actatgccaa
    55201 ggccatgaca ttctacagcc agttagacca agccttttca ttctatgagc ctgaatttat
    55261 ggagattagc gaaaagcagt atgctgactt tttagaagct caaccaaagc tgcaggttta
    55321 tcaacactat tttgacaagc tcttgcaagg caaggatcac gttctctcac aacgtgaaga
    55381 agaattattg gctggagctg gagaaatctt tggttcagca agtgaaacct tcgctatctt
    55441 ggacaatgcg gatattgtgt tcccttatgt cctagacgat gatggtaaag aagttcagct
    55501 atctcatggg atttacacac gtttgatgga gtctaaaaaa cgtgaggttc gccgtggtgc
    55561 ctatcaagct ctttatgcga cttacgaaca attccaacac acctatgcca aaaccttgca
    55621 aaccaatgtt aaggtgcaaa attaccgtgc taaagttcgt aactacaaga gtgctcgtca
    55681 tgcagccctc gcagcgaatt ttgttccaga aagtgtttat gacaatttgg tagcagcagt
    55741 tcgcaagcat ttgccactct tacatcgcta tcttgagctt cgttcaaaaa tcttggggat
    55801 ttcagatctc aagatgtacg atgtctacac accgctttca tctgttgaat acagttttac
    55861 ctaccaagaa gccttgaaaa aagcagaaga tgctttggta gtcttgggtg aggattactt
    55921 gagccgtgtt aaacgtgcct tcagcgagcg ttggattgat gtttacgaaa atcaaggcaa
    55981 gcgttcaggt gcctactctg gtggttctta cgataccaat gcctttatgc ttctcaactg
    56041 gcaggacaat ctggacaatc tctttactct tgttcatgaa acaggtcaca gtatgcattc
    56101 aagctatact cgtgaaactc agccttatgt ttacggagat tactctatct ttttggctga
    56161 gattgcctca actaccaatg aaaatatctt gacggagaaa ttattggaag aagtggaaga
    56221 cgacgcaaca cgctttgcta ttctcaataa cttcctagat ggtttccgtg gaacagtttt
    56281 ccgccaaact caatttgctg agtttgaaca cgccattcac caagcagatc aaaatgggga
    56341 ggtcttgaca agcgatttcc taaataaact ctacgcagac ttgaaccaag agtattatgg
    56401 tttgagtaag gaagacaatc ctgaaatcca atacgagtgg gctcgcattc cacacttcta
    56461 ctataactac tatgtatatc aatattcaac tggctttgcg gccgcctcag ccttggctga
    56521 aaaaattgtc catggtagtc aagaagaccg tgaccgctat atcgactacc tcaaggcagg
    56581 taagtcggac tatccactta atgtcatgag aaaagctggt gttgatatgg agaaggaaga
    56641 ctacctcaac gatgcctttg cagtctttga acgccgttta aatgagtttg aagcccttgt
    56701 tgaaaaatta ggattagcat aaaatggttg aatcgtatag taagaatgct aaccataaca
    56761 tgcgtcgtcc tgtcgtcaaa gaagaaattg tagacttgat gcgtcagcgt caaaagcaag
    56821 tcacaggttt cttgaaagaa ttggaagatt ttgcccgcaa ggaaaatatt cctattattc
    56881 cccatgaaac ggttgcttat ttccgttttc ttatggaaac catgcagcct aaaaatattc
    56941 tggaaattgg gacggctatc ggtttttcag ctctcttgat ggctgaacat gcgccaaatg
    57001 ctaagattac aactattgat cgtaatccag aaatgattgg ttttgccaag gaaaattttg
    57061 cccagtttga cagtcgcaag caaatcactc tcctagaggg agatgcggtg gatgtcttat
    57121 ctacactgac agagtcttat gatttcgtct ttatggattc tgccaagtct aaatacatcg
    57181 tctttctgcc agaaatcctc aaacatttgg aagttggtgg tgtggttgtc ttggatgata
    57241 tttttcaagg tggtgatgtt gccaaggata ttatggaagt ccgtcgtggt cagcgaacca
    57301 tttatcgagg ccttcaaaaa ttatttgatg caaccttaga caatccagaa ctcaccgcaa
    57361 cattagtgcc tttaggagat ggtattctca tgcttcgtaa aaaggtagca gatgttcaac
    57421 tgtctgaaag cgaatgattt tcagaaaaat ttaagaaaaa atagtaaaat agatagggta
    57481 acacttatct caaaggagta gacatgaaga aaaaactatt ggcaggtgcc atcacactat
    57541 tatcagtagc aactttagca gcttgttcga aagggtcaga aggggcagac cttatcagca
    57601 tgaaagggga tgtcatcaca gaacatcaat tttatgagca agtgaaaagc aacccttcag
    57661 cccaacaagt cttgttaaat atgaccatcc aaaaagtttt tgaaaaacaa tatggctcag
    57721 agcttgatga taaagaggtt gatgatacta ttgccgaaga aaaaaaacaa tatggcgaaa
    57781 actaccaacg tgtcttgtca caagcaggta tgactcttga aacacgtaaa gctcaaattc
    57841 gtacaagtaa attagttgag ttggcagtta agaaggtagc agaagctgaa ttgacagatg
    57901 aagcctataa gaaagccttt gatgagtaca ctccagatgt aacggctcaa atcatccgtc
    57961 ttaataatga agataaggcc aaagaagttc tcgaaaaagc caaggcagaa ggtgctgatt
    58021 ttgctcaatt agccaaagat aattcaactg atgaaaaaac aaaagaaaat ggtggagaaa
    58081 ttacctttga ttctgcttca acagaagtac ctgagcaagt caaaaaagcc gctttcgctt
    58141 tagatgtgga tggtgtttct gatgtgatta cagcaactgg cacacaagcc tacagtagcc
    58201 aatattacat tgtaaaactc actaagaaaa cagaaaaatc atctaatatt gatgactaca
    58261 aagaaaaatt aaaaactgtt atcttgactc aaaaacaaaa tgattcaaca tttgttcaaa
    58321 gcattatcgg aaaagaattg caagcagcca atatcaaggt taaggaccaa gccttccaaa
    58381 atatctttac ccaatatatc ggtggtggag attcaagctc aagcagtagt acatcaaacg
    58441 aatagtccaa atcaatgaat cagggaaaaa actcgacttc aggaaaaaat gaagcaaaca
    58501 ttcccacaat aaaacgcgta gtacaaggtt tgtactgacc cccaaaagtt agacaaataa
    58561 tttatccgaa ggatttagtt ctgtattgca cagggctaag tccttttagt tttaccttaa
    58621 ttctcttgtt gttgtaataa tcaatatagt ctataatggc ttgttccaat tgattaagtg
    58681 atttaaatgt tttctcatag ccataaaaca tttcggattt taaaatacca aagaaagatt
    58741 ccatcctacc gttgtcttgg ctgtttccct tgcgtgacat agatgcttga attcccttac
    58801 tctctaggaa ccgatgataa gaatcgtgtt ggtattgcca gtcttggtca ctatggagaa
    58861 tcgtattctc gtagtgcttc tctttgaatg cctgttccaa ca
//
LOCUS       DAVHSL010000006        57693 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000006 DAVHSL010000000
VERSION     DAVHSL010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.006"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            254..934
                     /locus_tag="VVR39_000369"
     CDS             254..934
                     /locus_tag="VVR39_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6029919.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDFIGLYYETDIALAMLVVAYLIILLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            894..1571
                     /locus_tag="VVR39_000370"
     CDS             894..1571
                     /locus_tag="VVR39_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6029920.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVILIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            1572..2329
                     /locus_tag="VVR39_000371"
                     /pseudo
     CDS             1572..2329
                     /locus_tag="VVR39_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            2341..3201
                     /locus_tag="VVR39_000372"
     CDS             2341..3201
                     /locus_tag="VVR39_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6029921.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGPSSGKTTAKARTID
                     ENKKSGELRIAVFGDKKPFDYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(3281..3928)
                     /locus_tag="VVR39_000373"
     CDS             complement(3281..3928)
                     /locus_tag="VVR39_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029922.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPTNLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(3925..4623)
                     /locus_tag="VVR39_000374"
     CDS             complement(3925..4623)
                     /locus_tag="VVR39_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029923.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(4633..5385)
                     /locus_tag="VVR39_000375"
     CDS             complement(4633..5385)
                     /locus_tag="VVR39_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029924.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(5385..6149)
                     /locus_tag="VVR39_000376"
     CDS             complement(5385..6149)
                     /locus_tag="VVR39_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029925.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYGLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(6245..6648)
                     /locus_tag="VVR39_000377"
                     /pseudo
     CDS             complement(6245..6648)
                     /locus_tag="VVR39_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6828..7460)
                     /locus_tag="VVR39_000378"
     CDS             complement(6828..7460)
                     /locus_tag="VVR39_000378"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU6029926.1"
                     /translation="MTLAKDIASHLLKIQSVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(7494..8195)
                     /gene="pyrF"
                     /locus_tag="VVR39_000379"
     CDS             complement(7494..8195)
                     /gene="pyrF"
                     /locus_tag="VVR39_000379"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU6029927.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKALGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNIHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(8428..9627)
                     /gene="divIB"
                     /locus_tag="VVR39_000380"
     CDS             complement(8428..9627)
                     /gene="divIB"
                     /locus_tag="VVR39_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU6029928.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVELAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(9637..10695)
                     /locus_tag="VVR39_000381"
     CDS             complement(9637..10695)
                     /locus_tag="VVR39_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU6029929.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     TELKSLADFYQLLKKDLS"
     gene            complement(10697..12049)
                     /locus_tag="VVR39_000382"
     CDS             complement(10697..12049)
                     /locus_tag="VVR39_000382"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU6029930.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(12153..12794)
                     /locus_tag="VVR39_000383"
     CDS             complement(12153..12794)
                     /locus_tag="VVR39_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6029931.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(12796..14817)
                     /locus_tag="VVR39_000384"
     CDS             complement(12796..14817)
                     /locus_tag="VVR39_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6029932.1"
                     /translation="MKKLFILLSTFFLSFFFAWIIVLRAPQYLYASYDSVTLLRVKKE
                     AQEPTREVFEQELEKFVNSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKQFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKAIADRKTPPYSLAFRMLLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWHDRVDYYQISFGL
                     GDRVNDTENQNKWYEFSKEAVEKEQALFVKENLIHFANPQGKNENGETLDTYSPDANV
                     LYVSPSYLDKENVAVNDETRQKLAHLQKGEFGLLLPESLRSQEAELKKVFEERLNYYG
                     KSSEDKDAPLEYEMRAIVSYLPTGQKRFVYNNGESPVSIQYLTDPILVVFTPTSTGDS
                     FISKYVWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILSSRDLVIGLLTLFVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(14888..15187)
                     /locus_tag="VVR39_000385"
     CDS             complement(14888..15187)
                     /locus_tag="VVR39_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6029933.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSVVSKWDSHSDKGSAPAGKTSEAWIWTKFGEQVSFYYDYD"
     gene            complement(15550..15804)
                     /locus_tag="VVR39_000386"
     CDS             complement(15550..15804)
                     /locus_tag="VVR39_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU6029934.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(15824..17665)
                     /gene="typA"
                     /locus_tag="VVR39_000387"
     CDS             complement(15824..17665)
                     /gene="typA"
                     /locus_tag="VVR39_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU6029935.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            17827..18552
                     /locus_tag="VVR39_000388"
     CDS             17827..18552
                     /locus_tag="VVR39_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEU6029936.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(18592..18819)
                     /locus_tag="VVR39_000389"
     CDS             complement(18592..18819)
                     /locus_tag="VVR39_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029937.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(18908..19288)
                     /locus_tag="VVR39_000390"
     CDS             complement(18908..19288)
                     /locus_tag="VVR39_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6029938.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(19288..19557)
                     /locus_tag="VVR39_000391"
     CDS             complement(19288..19557)
                     /locus_tag="VVR39_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU6029939.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            19621..20529
                     /locus_tag="VVR39_000392"
     CDS             19621..20529
                     /locus_tag="VVR39_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6029940.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(20583..21338)
                     /locus_tag="VVR39_000393"
     CDS             complement(20583..21338)
                     /locus_tag="VVR39_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6029941.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(21359..22288)
                     /locus_tag="VVR39_000394"
     CDS             complement(21359..22288)
                     /locus_tag="VVR39_000394"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU6029942.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(22303..22926)
                     /locus_tag="VVR39_000395"
     CDS             complement(22303..22926)
                     /locus_tag="VVR39_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU6029943.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(22919..24157)
                     /gene="hflX"
                     /locus_tag="VVR39_000396"
     CDS             complement(22919..24157)
                     /gene="hflX"
                     /locus_tag="VVR39_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU6029944.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFMPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(24150..25034)
                     /gene="miaA"
                     /locus_tag="VVR39_000397"
     CDS             complement(24150..25034)
                     /gene="miaA"
                     /locus_tag="VVR39_000397"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU6029945.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            25155..25325
                     /locus_tag="VVR39_000398"
     CDS             25155..25325
                     /locus_tag="VVR39_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU6029946.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(25373..26212)
                     /locus_tag="VVR39_000399"
     CDS             complement(25373..26212)
                     /locus_tag="VVR39_000399"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU6029947.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(26309..27268)
                     /locus_tag="VVR39_000400"
     CDS             complement(26309..27268)
                     /locus_tag="VVR39_000400"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU6029948.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(27395..28393)
                     /locus_tag="VVR39_000401"
     CDS             complement(27395..28393)
                     /locus_tag="VVR39_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6029949.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSNGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(28443..29060)
                     /locus_tag="VVR39_000402"
     CDS             complement(28443..29060)
                     /locus_tag="VVR39_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6029950.1"
                     /translation="MKLIFLHGLEQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(29061..30782)
                     /gene="pabB"
                     /locus_tag="VVR39_000403"
     CDS             complement(29061..30782)
                     /gene="pabB"
                     /locus_tag="VVR39_000403"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU6029951.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(30851..36538)
                     /locus_tag="VVR39_000404"
     CDS             complement(30851..36538)
                     /locus_tag="VVR39_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6029952.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKETSQQENPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVETDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSAAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKREAFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKSLLKNTDGFSGDLFTAPQA"
     gene            complement(36560..37123)
                     /locus_tag="VVR39_000405"
     CDS             complement(36560..37123)
                     /locus_tag="VVR39_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU6029953.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILSSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(37239..38930)
                     /locus_tag="VVR39_000406"
     CDS             complement(37239..38930)
                     /locus_tag="VVR39_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6029954.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VTFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(38927..39664)
                     /locus_tag="VVR39_000407"
     CDS             complement(38927..39664)
                     /locus_tag="VVR39_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6029955.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(39887..40999)
                     /gene="msrB"
                     /locus_tag="VVR39_000408"
     CDS             complement(39887..40999)
                     /gene="msrB"
                     /locus_tag="VVR39_000408"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6029956.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(41010..41576)
                     /locus_tag="VVR39_000409"
     CDS             complement(41010..41576)
                     /locus_tag="VVR39_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU6029957.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(41596..42306)
                     /gene="ccdA2"
                     /locus_tag="VVR39_000410"
     CDS             complement(41596..42306)
                     /gene="ccdA2"
                     /locus_tag="VVR39_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6029958.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(42517..43377)
                     /locus_tag="VVR39_000411"
     CDS             complement(42517..43377)
                     /locus_tag="VVR39_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU6029959.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(43556..45610)
                     /locus_tag="VVR39_000412"
     CDS             complement(43556..45610)
                     /locus_tag="VVR39_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU6029960.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIVLTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(45622..45876)
                     /locus_tag="VVR39_000413"
     CDS             complement(45622..45876)
                     /locus_tag="VVR39_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029961.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQVHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(45869..46426)
                     /locus_tag="VVR39_000414"
                     /pseudo
     CDS             complement(45869..46426)
                     /locus_tag="VVR39_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(46410..47357)
                     /locus_tag="VVR39_000415"
                     /pseudo
     CDS             complement(46410..47357)
                     /locus_tag="VVR39_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241739.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            47468..47827
                     /locus_tag="VVR39_000416"
     CDS             47468..47827
                     /locus_tag="VVR39_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU6029962.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            48037..48893
                     /locus_tag="VVR39_000417"
                     /pseudo
     CDS             48037..48893
                     /locus_tag="VVR39_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(49141..55827)
                     /locus_tag="VVR39_000418"
     CDS             complement(49141..55827)
                     /locus_tag="VVR39_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU6029963.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKIF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPSSEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQVGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKVKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTIRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(55987..56064)
                     /locus_tag="VVR39_000419"
                     /pseudo
     CDS             complement(55987..56064)
                     /locus_tag="VVR39_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(56087..57562)
                     /locus_tag="VVR39_000420"
     CDS             complement(56087..57562)
                     /locus_tag="VVR39_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6029964.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(57610..>57693)
                     /locus_tag="VVR39_000421"
     CDS             complement(57610..>57693)
                     /locus_tag="VVR39_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6029965.1"
                     /translation="PILFRIPAMSAPVFDNIEAAIKEHGLS"
BASE COUNT        16811 a        12717 c        10554 g        17611 t
ORIGIN      
        1 tctacatgac cttctgcatt gcttgttttg tatgacataa aatgtcctcc ttaataagta
       61 agcgtttact ttgtatatta taaaaatatc ttaactcttt tttcaaaact tttcaaatat
      121 tttgtttgga aatttcagaa attttatgtc tatggtaaaa aatccttata acggcaataa
      181 aaaatagata ttatccaaag aagattttaa gtgctacaat aactgtatta tttctagatg
      241 ggaggttcta tttttggatt ggtccattgt tgaacaatat ctaccactat atcaaaaggc
      301 attctttctg accttgcata ttgcagtttg gggaattttg ggatcctttc tgctcggttt
      361 aatcgttagt atcatccgac attatcgaat ccctgttttg gcgcaagtag cgacagccta
      421 cattgaattg tcacgtaata cgcccctttt gattcaactc ttctttctct acttcggtct
      481 tccccgaatc gggattgtcc tatcttcaga agtctgtgca acgcttgggc ttgtcttttt
      541 aggaggctcc tatatggcag aatctttccg aagtgggctg gaagccatca gtcaaaccca
      601 gcaggagatt ggcctcgcta ttggtctgac acctctacag gtctttcgct atgtggttct
      661 tccgcaagca acagcggtgg cactcccctc ctttagtgcc aatgtcattt tccttatcaa
      721 ggaaacctct gttttctcag cagtggcttt ggccgacctc atgtacgtcg ccaaggattt
      781 tattggtctc tactatgaga cagacattgc gctagctatg ttggtagttg cttatctgat
      841 catactgcta cccatctcac tggtctttag ctggatagaa aggaggctcc gccatgcagg
      901 attcgggaat ccaagtactc tttcagggaa ataatctcct gagaatctta cagggattgg
      961 gcgttacgat tgagatatcc atcctgtctg tcctcttatc catgatgttc ggaacagtca
     1021 tgggaatcat catgacctcc cattctagaa tcatacgatt tttaacacga ttgtatctgg
     1081 actttacccg tatcatgccc cagctggtgc tactcttcat cgtttacttt ggcttagctc
     1141 gaaactttaa tatcaatatc tcaggtgaga cttcagctat tatcgttttt accctctggg
     1201 gagcagctga aatgggagac ttggtacgtg gagctatcac ttctctccct aaacatcagt
     1261 ttgaaagtgg acaggcactc ggcttgacta atgttcaact ttactaccac atcatcatcc
     1321 cacaagtctt aagaagactg ctaccgcagg ctatcaatct tgtcactcgg atgattaaaa
     1381 ccacttcatt agttattttg attggggttg tggaagtgac caaagttgga caacaaatca
     1441 tcgatagcaa tcgcctgacc atcccaactg cttcattttg gatttatgga accattctag
     1501 tcttatattt cgcagtttgc taccctattt ccaaactatc cactcactta gaaaaacatt
     1561 ggagaaacta aatgtctgaa actatcttag aaatcaagga actaaaaaaa tccttcggag
     1621 acaatcccat cctccaagga ctttctctag aaatcaaaaa agggaagttg ttgtcatcct
     1681 agggccctct ggttgtggga aaagtaccct ccttcgttgc ctcaacggct tagaaagtat
     1741 tcaaggtgga gatatttttc tggatggtca gtctatcgtt gaaaataaaa aagattttca
     1801 cctagttcgc caaaagattg gcatggtctt tcaaagttat gaactctttc cccatctgga
     1861 tgtcttacaa aacctcatcc taggccctat caaaactcaa ggaagggaca agaaagaagt
     1921 aacggaagaa gctttgcaat tactagatcg tgtcggtttg ctggataaac aacatagctt
     1981 tgcccgtcaa ttatctggtg gacagaagca acgtgttgca attgtccgtg ccctcctaat
     2041 gcatccagaa atcatccttt ttgacgaggt gactgcttcg ctggatccag aaatggtgcg
     2101 tgaggtgctg gaacttatca atgatttggt ccaagaaggc cgtaccatga ttttagtaac
     2161 ccacgaaatg cagtttgccc aagccattgc tgaccggatt atcttcctcg accaagggaa
     2221 aatcgctgaa gaaggaacag ctcaagcctt ctttaccaat ccgcaaacca aacgagccca
     2281 ggaattttta aacgtctttg actttagcca attcggctca tatctataaa ggagattctt
     2341 atgaaactat tcaaaccact cttaactgtt ttagcacttg cctttgccct tatctttatc
     2401 actgcttgta gctcaggtgg aaacgctggt ccatcctctg gaaaaacaac tgccaaagct
     2461 cgcactatcg atgaaaacaa aaaaagcggt gaactgcgaa tcgccgtgtt tggagataaa
     2521 aaaccgtttg actacgttga caatgatggt tcttaccaag gctacgatat tgaactagga
     2581 aaccaactag ctcaagacct tggtgtcaag gttaaataca tttcagtcga tgctgccaac
     2641 cgtgcggaat acttgatttc aaacaaggta gatattactc ttgctaactt tacagtaact
     2701 gacgaacgta agaaacaagt tgattttgcc cttccatata tgaaagtttc tctgggtgtc
     2761 gtatcaccta agactggtct cattacagac gtcaaacaac ttgaaggtaa aaccttaatt
     2821 gtcacaaaag gaacgactgc tgagacttat tttgaaaaga atcatccaga aatcaaactc
     2881 caaaaatacg accaatacag tgactcttac caagctcttc ttgacggacg tggagatgcc
     2941 ttttcaactg acaatacgga agttctagct tgggcacttg aaaataaagg atttgaagta
     3001 ggaattactt ccctcggtga tcccgatacc attgcggcag cagttcaaaa aggcaaccaa
     3061 gaattgctag acttcatcaa taaagatatt gaaaaattag gcaaggaaaa cttcttccac
     3121 aaggcctatg aaaaaacact tcacccaacc tacggtgacg ctgctaaagc agatgacctg
     3181 gttgttgaag gtggccatta actcttaaaa gggactggat tttaagctcc aatccctttt
     3241 taagatttta cctataacat cctgagtcta tctaagatgt tcaatctgaa cacagtgtac
     3301 atactttatc ttctattgca tatactttat cacataagat acgaatatcc tcttcactat
     3361 gactagcaat caaaattgtt gtcccttttt cactagagag ctttctaaac aatgttctca
     3421 tattttctac acttgattta tccaaggcat tcataggttc atctagtaaa agaatagagg
     3481 gattctccat aattgcttga gcaatcccta gctttttcct catacctagc gaataagttt
     3541 taactttctg gtctttttgc tcatatagac caactatttt cagtgtatca ttgatttcct
     3601 gattaccaac tactcctcgt atgcttgcca aatattgtaa attcttaaag ccactataat
     3661 aatttataaa accaggttct tcaatcaaag ctcccaaatt agttggaatt tttctctcag
     3721 gaacaatatt ttccccattg attaacactt ctccataaga cggactatat aaaccagcta
     3781 ttaatttaaa caatacactt ttccctgagc cattcgcacc agtaattcct ataatttccc
     3841 cctgtttaca actaaagtta aggttttgaa aaacacatgt cttttttaat ttcaactcaa
     3901 tattttttaa tgtaattatt tcattcattc tataaacctc ctcttttgac gagtgaaata
     3961 gaaaatgctt tgaaaaagaa agactaaaaa tagcaactga agaaataaat ctcgtcctat
     4021 atctccattc cctcgattca aaatataaaa tagataatta gttcgatttc ctacaaatag
     4081 accaccaaac acaatcatga gtaaaaagaa actaacgcaa gcaaagttca tttgtacatt
     4141 cgctcctagt gcgtataaca taaagcaaaa caagactaac acacaagcat tcaaagaatc
     4201 aactataaac aaaactccta tatcccagtt tggtaactgt aacataaatt gaatcactag
     4261 aacttttacc atgattaaaa tgagtccata aagaaaacag gtccaaatct gatacctaat
     4321 ccagagctta atagaagaaa atcgaatcac ttccataaag aaatcggatg ctcttctacg
     4381 atatacaact gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc atatagataa
     4441 gactaaaaaa gagttttgac tcagattagg cccttttaaa atttctataa caagtctatc
     4501 atttccttct aaccaatacc ataatcctaa acaaatcaat atccaaaaaa gaacataacc
     4561 ccaaaagtac ttggtataga ttatctgatt caacctccac atgtgactac ttaactttcc
     4621 catttccaac ttttacactc tcctccagtt tctatgaaca gaaaatacag tcaatggaat
     4681 tatgatagat agtaatgtaa gccaataaat caatgcatac ggattggaat ttaccatata
     4741 ctgaaaaatt ggcaataatc caattatccc attgtccaac tgataaatcc agaataagga
     4801 ttctacaaat aaaaaagtaa acagaaatac taagctcatg tttgattttt taaaccaaga
     4861 aaaactgcta atagtaagta aggataaaaa gaaatagtat gctatataag agaaaaaaaa
     4921 tcctataaag aaactagcat tgtttgcaat acttatacca taaaattctc ttaaaaaatc
     4981 aacctccttt atctccaaag agaagctaaa accattacta aatgcaatca gaaaaatcaa
     5041 taaaaataaa gtcgccgtcc aaatccccgt actaagagct gctaatttga aactaaaact
     5101 ggtaaagtgc ttaattgatt tcagacgaat acgacactcc aacctattaa aatagttatt
     5161 catcaaataa aaaaagaata atatatatgt gaacggaaag caatatactc cagtcgtcat
     5221 atcttgaagt aaaactaaga tccattctaa tacatttgga tggattgaat attggcgaca
     5281 gcgcaataaa tatactgtac tagataaaac acaggatagc agtaatataa aataaaccaa
     5341 tactgctaag aaatcttttt tataaaattg aacaaattgt ttcattatac atagtcctct
     5401 gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa caaataaaat aaaagcaaga
     5461 tgcccactaa ctaaggaaag actgatatct ttctgatatc ccaaagctag cgttgtcaca
     5521 ggttctaagt aagatagccc taaaatagcc caaaaaatac caccaaccat catataggca
     5581 actgggatga aaatagctcc tatttttttc ttcactagca aagcactagc tagtccaaaa
     5641 atagagaaca cagcgcccca aactccatac cagagagtcg ttacaagacc atagagaaac
     5701 tgattggaat caaataattc ttttaaggca ccactataat ctccaatata aatttcctga
     5761 taaggagtca ctaaaagatt aattcctaat aataataaat aggggagaaa aaagactaga
     5821 aaagaagaaa taattgcagt actacctaca atagctagat acctcttttt agaaattcgg
     5881 cacaattgtg ctgttagaaa atgactctca gcatcctcta ttatctgact agaatagggc
     5941 agtgtacaga taagtgcagc tactaggcta atcggtgaaa atcctcgaat agaagaagcg
     6001 gcaaaaaaaa tcgataaacc ttcaatttta taaataccat tgaaagcaag gaaatttcct
     6061 aaactcatgc aaagaagggt caaaaataaa gacatataaa atcgaggtga ttgaacgact
     6121 cgtacaagat tacaaatgaa aaattccatc cttactcctc cttataataa aaatagggtg
     6181 tagcattctt ttttcatgct acacccacaa tcaaccatct ttaaggctta ctctgacaag
     6241 taagttaata agaatctgga ctccaagaac ctgaagtatg aattcttaca tgatttccaa
     6301 attgtggcgc catagctaat ctagtaccag aaccaatata attgtcacca cctccattat
     6361 agtacatgac aatcctagag ccagacccca atgaatatac cggggtaata tctgacccac
     6421 tataggcgct acgaatagag gtatttaacc ttttaccgcc accagtgctg tcactattat
     6481 taattccagc agaggcgttt tctttctcaa gctcactagt tgtatccgaa ccccaacgcg
     6541 gcaacgttaa atcataattt ccaatctgtc tagctaaaac tgtagggaga aacaaactag
     6601 atgcaattgt aactacgcaa aaaaggaata tatttttctt cttttcatga catcgtcctc
     6661 ttaagaagtg ataaacaaga tagttgattg atcaatttga tacatattac attttcatta
     6721 tatcaataaa agaaagcgtt gtcaattatt ttatttaaaa tattgtcata ttttaaataa
     6781 aatggtaaaa gagactcggt agcctcgtct ctctttatct tactgaccta accttcttgc
     6841 caattttctt ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg cgtgatgtaa
     6901 ccttcttctt gggctagatg gataagctcg ctatagtttg aaagcgtcac aagtttaaca
     6961 ccagcatctg caaagttctt atctgctttt ggcaattggt agctgaaaat cgctacaact
     7021 ccaagcacat ctgctccttc tcgcttggct gctgctacag cttcaagaac tgaaccaccc
     7081 gttgaaataa ggtcttcaac cactaccatt ttttgacctt gagctacgcg accttcgatt
     7141 tgattaccag ctccatggtc ttttggtttg ctacggatgt aggcaaaagg caagtccatc
     7201 ttatcagcaa taatggctcc gtgtggaatc cctgctgttg cagttcctgc aatcacttct
     7261 acttcaggaa aggcttcttt gatagcttcc acaaaaccat tttcaattag ggtacgagtt
     7321 tctggatagg ctagtgtcac acgattatca gtgtaaatcg gtgacttgat accagatgcc
     7381 caagtgaagg gttcctctgg tttgaggtaa acggattgga ttttcaagag gtggctagcg
     7441 atatctttag caagtgtcat ggtattctcc ttttattttt ctaatctagt tctttaattc
     7501 cagtcctgtg tccattcatc cttgatggca tgataagctg caacaggatc ctcagcttgg
     7561 gtaatgggac gtcccactac gatatagtca ctgccgattt gataggcatc agcaggtgtc
     7621 atgactcgtt tttgatctcc aactgcaaca ccagctggac gaatccctgg tgtcagacag
     7681 ataaaatctg gattggtagc ctgcttgatg acttgtactt cctgagccga gcaaacaaca
     7741 ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa tcacagactc ttgcagactg
     7801 gtttggatat tttgaaactc ctgcatctga gcttctgacg ttgatgtgag ctgcgttaca
     7861 gcgatcaatt tggcttgact tccaagacct tcacgcgcag ccttcatcat ctctacacca
     7921 ccagccgcat gaatattggt catatccaca ccaagctgag ataggatctt cattgctgac
     7981 ttgactgtat taggaatgtc atgaagtttg agatccaaaa agacactgtg acccagggct
     8041 ttcaaataag acacaatctc aggccccgct gcgtaataaa gctccatccc taccttgaga
     8101 taaaggcttt cttctgctgg gaaaagagct aaaaattcct tgaccgcctc aaaactagga
     8161 aaatcaagag caatgactgg acgatgttct cgcataggtt tctcctttta cctttactag
     8221 tgagagagtc tggccaacag aagccacgaa aaaaggaacc tgccaacagc aaggttccac
     8281 gaaaaatggg tagtctccac cctttcaccg tctaacctta gctgcctctc tggactgctt
     8341 taaaggtttt ctattattct attatttcta ctagcacttg tcaagtaaaa acttagtcac
     8401 taaagaacta taagagaaaa ggtaaaccta gcgacgcgat gagcgctggg tcgtttgatt
     8461 tcgattgctc tcttcctctt gttttttctg ttcttcttcc tgttttttct cagcttcctt
     8521 ggcctcttgt ttggcttttt cctcagcctc cataattaat ttatccgcca cagtgtaact
     8581 gtaaattcca gcttccatgt caatcacact cggttctgac aattgtggct taatcttact
     8641 gtaatatggc agtttcttac tcatttcaga tagaggaacc aagacttcgt ccgaatcatt
     8701 catggtcaat cgaattaaat cggatgtcac cttgcttggg gctaattcca ccttttggat
     8761 agccgccttg agttctgggc taatttgagc aagttctgag acaaaaacct tgatttgttc
     8821 actatcatta aagagaactg ataaataagt ttctggtaaa ctgttcagac tcacagaact
     8881 agtctcaagc tgaccactgg aaagaatagg ataatgattt tcaccagaaa tatagtaggc
     8941 cacaatatca tattccttga ccttaatagt gaacttagtt ggaaattgat agacaagttg
     9001 agctaattca acccaatagt tagacttaat ctgcttttca tattttgcct tgtctagcag
     9061 aaggttaatc gtataatccg aatcctgaat gcctgaagcc tgtcgaatat catcagctgt
     9121 agtttgcacc gttccctcaa cacgaatatc tttcatggtc gcataaggac tgagcaagta
     9181 ggcagagaca atcaataaaa gcagacttgg aaataaaatc gtgaaggctc gcaagatatg
     9241 gataccagga atctttgctt tggctggttt ttcctttgta gcctttttag aaagcttttt
     9301 atcctgttcc tccttctctt tagactctgg ttcttctttc tcttctttct ctttgtcagc
     9361 ctctgaggat gctacttttt cttcagactc ttccttagct gattctgaat cttcctggtc
     9421 tgtttcactc tcctggtcct gtttgtcctc tgacttctca gattcttctc ccattcgagc
     9481 ttgtctttcc ttttccttct cctcagctag agccgcctct tcttcagcct tcttttttag
     9541 atattcttgg tttcgtttct gccattctga taactctttc aattcttcga ggatttcttt
     9601 gtcctcattt ttcttatctt ttgacattta ctttccttat gataaatctt ttttcaacaa
     9661 ttgataaaaa tctgctagag atttcaattc cgtagaagcc ttcatcttag cttggtaatc
     9721 ttccttgtga cttagtaagt gagaaagctt ctcttccaaa ctatccaagg tcaaatcgct
     9781 ttcttgaagg tcttctgcat agcctttttt tacaaagtaa gctgcatttt caatctggtc
     9841 accacgacta gcttcacgac caagcggcac aatgacatgc aattttgcta tcgccaagag
     9901 ctcaaaaatc gtattggcac cacctcgtgt cacaacaata tcagccaatt ccatcaaggg
     9961 ttgatagaga tcggtcacat agtcaacacg aaaaagattt tggctcaact cattcaggct
    10021 agaatctcca gttagattga taatattgta gcgctctgtt agttctttct tatggtctgt
    10081 caccaattgg ttaaagacac gagcacctgc agaaccgcca acaaacaata cagtcggcaa
    10141 tttatgatta aaatggcttt gaatatccac caattcatct ggttctggat ttttttgatc
    10201 tgaaaccttg gtcactgctc ccacatgctc aaccttagac aaactcgaag cttgctcaaa
    10261 ggttgaatac atcttagtcg caaatttata ggcgatttta ttggccaagc ccatagacag
    10321 gtcagattcg tgaataaaga caggcactcc tgacacacgc gcagcgataa caggcggtac
    10381 tgagacaaag cccccctttg aaaaaagggt ctgtggacga agtcgcaaca tgataaagag
    10441 cgattggacg attccccagc caactttgaa gacgtccagc atattttgcc aagagaaata
    10501 gcgacgcaat tttccagtcg caatagaatg gaaggtgaca tccaaacctg acttaaggat
    10561 ttcttggtgt tcgataccac gcttgtcccc gatatagtgg acttcccaac catcttcgat
    10621 gaacttgggc attaacaaaa gattgagggt aacgtgtcca accgtccccc cacctgtaaa
    10681 gacaattttt ttcatattat tcttttaact ccgctactgt gtcgataaag aggtcgccac
    10741 gtacttcaaa gttagcatac atatcccagc tggcattggc aggactaaga agaaccacat
    10801 ctccttgagt cgcaagctca taggccttgc gggtcgcatc tgcaatatct gtcgcctcca
    10861 cataagcgac accagccttg tctgctgccc gtttgacacg ttctgcagat tgacccagga
    10921 tgaccatctt cttgagtcca gtaatgtctg gcaccaattc gtcaaactca ttgccacggt
    10981 ccaaaccacc tgcaatcaag acgaccttgc tgttatcaaa tcctgacaag gctttttgag
    11041 tagccaagat attagttgat ttactgtcgt tatagaattt aacacccttg atgtcatcca
    11101 caaactggag acggtgtttg acaccaccga aggctgaaag agtttccttg atggtttgat
    11161 tgtccacacc acgaagcttg gctacagcaa tagtcgcaag ggcattttcc acattgtggc
    11221 tacctggaac accgatttca ttcgctgcca tgactacttc accacggaag tagagttgac
    11281 catcttccag ataagctcca tcaacctttt caagtgttga aaatggtaca acagtggctt
    11341 ctgtcttgga agtcaagtct tttgccaagt cttgattaaa gttcaagaca aggaaatcag
    11401 ctgctgtcat cttgttctgg atattccact tggctgctac atattccgaa aatgacccat
    11461 ggtagtcgat atgagttggc atgaggttgg taataaccgc aatctctgga tggaattctt
    11521 gaacacccat gagttggaaa gaagaaagtt ccataacaag cgtgtcctta tctgatgcta
    11581 tttgagcaac ctgactagct ggatagccga tattccctga taaaagacca tgttgcccag
    11641 cagcagtcaa aacttcccca atcatagtcg ttgtggttgt cttaccgttc gatcctgtga
    11701 taccaataat cggtgcttct gaaatcaaat aagccaattc cacctcagtc aagactggaa
    11761 ttcccttggc caaagccttt tcaatcatgg gattgttgta ggggatacct ggatttttca
    11821 ccataagggc aaactcttca tccaagagtt ccaaaggatg gccacctgta atgaccttga
    11881 tcccttcttc cagcaaactt tgggcagctg gattgtcctc gaaaggcttc ccatcattta
    11941 ctgtcacaat ggcacctaac ttgtccaaca aacgagccgc agattcacca gacttggcca
    12001 aacctaaaac aaggactttc ttatttttaa attgatctat tactttcatg tctcgaactc
    12061 catttctact cctactattt taccattttt atggaaataa aaaagccaca aagtgtgttt
    12121 gtgactcttt cttctaactg aatcttacca tatcatctat gtgataaatc ggtaactcga
    12181 atgacctgat ccacttgctc ccaaatcaga ggattgtggg tcgcaataat aatggtccga
    12241 ttcggatttt ttaaagattc taggatggaa agtaattcct cagagttttt ggggtctaag
    12301 gaagcggttg gttcatctgc gaggatcaaa ggtggatcct ttaaaattat cttcgctaat
    12361 gcaacacgtt gtgcttctcc tcctgataac tcaaatatag gttgcttcaa atccaaataa
    12421 gagaggttta cacggtttag agcttgtttc atcaaagaga ttttctcttt ttccttcaac
    12481 tttttaccaa ctaaacccag attgagattc tctttgacgg tttggctttc aattaagcca
    12541 aaatcttgaa ataagtatcc caagtaatct ctaaagaaaa cagaaggctt gatgtcctta
    12601 agagaagtac catcatagat gatttgtcct ttgtcatatg gctctaatcg tccaatcata
    12661 ttcaagagtg ttgtcttacc acagccactt gtaccgatta aggcataaat tttcccacct
    12721 tcaaaatgaa gattcgtatc tgaaaatagc tgacggcttc caaatttttt agatatattc
    12781 tttagttcaa tcatcctatt ttcctttcat aattgtcata gaaacacgag attctttctg
    12841 cgcttgacgg taaagcgtca aaactgcact agctagaaag acgaataaag tgagcaagcc
    12901 aatcaccaag tctcgactgc ttaaaataaa gaaactagca ccaaatacaa aactggcaaa
    12961 ttggctaacc atatactgag catgtgtttc aaaaaatcgt aaacctgaaa ttcgtttaat
    13021 caagatatct cggcggaatt gctcgaaata tagaagattg acagaataaa agagtaataa
    13081 ggaactggct atcccaacaa tagctcctaa gattaaagtt gctgtttcag tttgaacttc
    13141 attataacga gttagataaa cacttcttcc ttctttaaga taggatactt gctcataaat
    13201 tccagctttc tttaagagtt ctagcccact ctcatatcct ttgataaaga gttgttttcc
    13261 agcattgata gaccaaacat attttgaaat gaaactatca cctgtagatg ttggagtaaa
    13321 tacaactaaa atcggatcgg ttaagtactg aatagatact ggactttcac cgttattata
    13381 aacaaagcgt ttttgtcctg ttggaagata gctaacaatc gctctcattt catactctaa
    13441 aggagcgtct ttatcctcgc ttgattttcc gtaatagttc aaacgttctt caaaaacttt
    13501 cttaagttct gcttcctgtg aacgaagaga ttctggtaat aagagtccaa attccccttt
    13561 ttgaagatga gctagtttct gtctagtctc atcatttaca gccacatttt ccttgtctaa
    13621 ataacttgga ctcacataga gaacattagc atctggacta taggtatcca gtgtttcccc
    13681 gttttcattt tttccttgag gatttgcaaa atgaatgaga ttctctttta caaatagagc
    13741 ctgttctttt tcaactgctt ctttggaaaa ttcataccac ttattctgat tttctgtatc
    13801 atttactctg tcacctaagc caaaagaaat ttgataatag tctactctgt catgccatgc
    13861 ttgttttgaa atttcaagtt ctttcaatcg ttggtaagac gtcaaacctg tcttaacagc
    13921 gtatcccact gtaaagacag caaccaactg acacaatagg gttaaaatca tcaggcgttt
    13981 aaggggtaat cttcccttaa taacgggaac taatgctttg taactcaaac tcattagata
    14041 aaggagcatt agtaaaattg aaatcgccaa taaaaacaac agatagaaac taatcccaaa
    14101 accataggtg gctaacaaga taggataaaa caaaccttga ctaaaaagaa cgactccccc
    14161 acctaggaag gaaaggaggg ctgatagaag gagccactta atatcagtag ataaagaatg
    14221 ccccataatg gataagagag tctgaccaga aaagagtttt atacctgctg ctctcatttc
    14281 cttaatccga gtgataatca ctaaagcaaa gaaagataag ccaaatattg ctaaactaat
    14341 taaaataagg ggatttagta acattcgaaa agcaagagaa tagggaggtg tctttcggtc
    14401 agcaattgct ttataaccta aatctcctaa tttatcagct agcttttctt ttgtcaagga
    14461 gcctgataaa aggagataac tatttagcgg atcactacgt tcacgacttt cttggctagc
    14521 ttcttggaat tgttttggta atgttccctg accataagtt gcataagtaa agtgagtcgt
    14581 cccatcctta ctcggttcta caattctcct agctattaaa ctctgttctg agtttacaaa
    14641 cttctccaat tcctgttcaa atacctcacg agtcggttcc tgagcctctt ttttgacacg
    14701 aagtaaagta acggaatcat agcttgcata taaatattgt ggcgcacgta agacaataat
    14761 ccaagcaaag aagaagctga gaaaaaaagt tgatagtaat atgaatagtt tcttcatagt
    14821 agactccttg taaacaaaat tccccctgta atttcttaca aggggaatta tctaagaaaa
    14881 ctaaatatta gtcatagtca tagtaaaatg atacttgttc cccaaattta gtccaaatcc
    14941 aagcctctga agttttccct gcaggtgctg atcctttatc tgaatgacta tcccatttac
    15001 ttacaacaga agaataatga tattttttac catgatagta atttgaaaaa gcccaaccac
    15061 ctcctgaacc ttctccatat gtccatactc ctccatctgg atattgtaca gcagctgatg
    15121 cagctcccaa taatgtaaag cttgaaataa gagctagagc aagtaatcta tgttttttcg
    15181 ttttcatttt atttttcctt tcaaaaaaag cacaccctga gcaacaatgc aacaaaataa
    15241 atcctcctct ctcttttttg aaaccgattt cttatataat aagaatagca tttttattat
    15301 ttgttgtcaa ggaaaaaatc gaatttttta gatgttttac tatattatct ctatgaataa
    15361 tattatatag tagttttatt ttaaaataat atgcaaccag tactaaccaa atataaaata
    15421 gatgccatta acgaatttta ttcaagtttt tcccattcat actatacaag caaaagagat
    15481 ggtgttaact aaaaagcaat tcaaactatt ataaaattcc tagcaaaaag agagccgaaa
    15541 ctctcttttt tatcttcttt tacttttttt gactggcatg agtgtgatgt ctctaacact
    15601 aaagtaagct aggatcaaca tggctattgc taggaatatt tctgttggta attgaaaaat
    15661 tttcagaaaa gatagaacca ataaaatcaa gagtgccact aaaatacata ccatagcgac
    15721 gatattgact gtccctttaa tgctttctgg tgtcgcaaat acatagagta ggagcagtaa
    15781 aattcctagg actaaataga ccatctttct ctctttctag ctcttattca gctgattttt
    15841 tcttcttgtt agctttctca cgctctgctt tgttaaggat ttgtttacgc aaacggatag
    15901 actcaggcgt tacttccatg tactcatcgt cgttcaagaa ctcaagagac tcttcaagtg
    15961 tcaagatacg aggcgtcttg ataacagctg tttggtcctt agtagctgaa cgaacgttgg
    16021 tcatttgttt tgccttcgtg atgttaactg tcaagtcatt ttcacgagag ttttcaccga
    16081 tgatcattcc ttcataaacc tcagtacctg ggttgacaaa gatcgtacca cgttcttcga
    16141 tagacatgat tgagtaagtt gtagccttac cagcatcgat agaaacaagg gcaccacggt
    16201 gacgtccacc aatttcccct ggaatcaatg gcaagtattg gtcgaaggta tggttcatga
    16261 taccgtaacc acgagtcatt gacaagaact cagttgagta tccaatcaaa ccacgcgctg
    16321 gaacaaggaa gaccaaacga gtttgaccat taccagttga aatcatatcc aacatttcac
    16381 ctttacgttc agaaaggctt tggataacag acccttggta ttcttctgga gtgtcgattt
    16441 gtacacgttc aaatggttca catttaacac cgtcgatttc ttttacgata acttctggac
    16501 gagatacttg aagttcatag ccctcacgac gcattgtttc gataaggatt gacaagtgca
    16561 attctccacg tcctgaaaca gtccatttat ctggtgaatc agttgggtca acacgaaggg
    16621 aaacgtctgt ttgcaattct gcctgcaagc gttcttccac cttacgagaa gttacccatt
    16681 taccttcttt accagcaaat ggtgagttgt tgaccaagaa agtcatttga agagttggct
    16741 catcgatgtg taggattgga agagcttcta ctgcatctgt cggagtgatg gtttcaccga
    16801 caaagatgtc ttccatacct gaaacggcaa tcaagtcacc cgctttggct tcttggattt
    16861 cacgacgttc caaaccaaag aaaccgaaga gttttgtaac acggaagttt ttagttgtac
    16921 cgtcaagttt agaaagggta acttggtccc caaccttaac tgtaccacgg aagacacgac
    16981 cgataccgat acgtccaacg aagtcattgt agtccaaaag tgacacttgg aactgcaaag
    17041 gctcatctga gttatctact ggagctggga tatggtcgat aatcgtgtca aagattggtg
    17101 ccatagtcgc ttcttggtca gctggatcat ctgacaatga agaagttccg ttgatcgctg
    17161 aagcataaac cactgggaaa tcaagctggt cgtcatctgc accaagctcg atgaaaagtt
    17221 ccaagacttc atccactact tctgctggac gagctgatgg cttatcgatt ttgttaacaa
    17281 ccacgattgg gacaaggtct tgttccaagg cttttttcaa tacgaaacga gtttgtggca
    17341 tggttccttc ataggcatct acgaccaaga caacaccgtc aaccattttc atgatacgct
    17401 caacttctcc accgaagtcc gcgtgtcctg gtgtgtccat aatgttgata cgagttccgt
    17461 tgtaagcaac ggcagtattt ttagcaagga tggtaatccc acgctctttt tcgatatcgt
    17521 ttgagtccat agcacgctct gccaattcag tacgtgcatc aagcgtttct gattgtttca
    17581 ataattcgtc aaccagggtt gttttaccgt ggtcaacgtg ggcgataatc gcaatgttac
    17641 ggatatcttc tcttaatttt gtcatgattt cctctataat attcaaaatt tattttctaa
    17701 ctgaacgatt ataccataat ttcaaataaa taacataact caagcaagtg taaatgtttt
    17761 cactccgctt ttcttttcac gtcaagcctt ttcaaagcaa gcgacttatg ataagatagg
    17821 cacagtatgc gtttagataa tttattagct caagaaaaaa tcagccgaaa ggccatgaaa
    17881 caagccttac tcaaagggga cattctcgtc gatagttgcc cagcccgatc cctagcccaa
    17941 aatatcgata caggactaca agaactcctt tttcaggatc gaatcattca aggctatgaa
    18001 cacacctatc ttatgcttca taagcctgct ggtgtcgtta cagccaacaa agacaaggaa
    18061 cttccgaccg tcatggacct gcttccatct gacatccagt ctgacaagct ctatgccgtt
    18121 ggccgactgg accgagatac aacgggactc ctcctcttga ccgataacgg tcccttgggc
    18181 tttcagctcc tccatcccca atatcatgtc gataagactt accaagtcca ggttaatgga
    18241 cttctaacac ctgaccatat ccaagccttt caaaagggaa ttgtcttttt agatggtact
    18301 gtctgtaaac ccgcaaaact agagattcta tctgcaagtc cctccctcag tcaagcctct
    18361 atcaccattt cagaaggaaa atttcatcaa atcaagaaaa tgttcctctc ggttggtgtt
    18421 aaggtgacta gcctcaaaag aatccaattt ggggacttca cattgaaccc agatttagca
    18481 gaaagtaact accgcccttt gaaccaaaaa gagttacaaa tcattaaaaa ctatttagag
    18541 atgagtcgat aaaacaaaaa aagctttaaa actaaagctt ttttctttta tttaccgaaa
    18601 aattaaggcg attgctacaa tccagttaac tacagaaatc acaattccta agatattaag
    18661 aatcttttct attttatagt ctaattgtga ctctttttgg tatgaaatag ccaagaccaa
    18721 tcctatgata cccaaaatca ggcctacaat tggaaataac aaaccaagaa taatcgacaa
    18781 gatacccaca aaaagtggat ttttcttctt ttctttcatg ttctaagaac tctttaaatt
    18841 ttatacaaat taattatact ataaaacaat agcttcatcc tatcattcga ctaatttgga
    18901 aataaggtta gctagtcttc actttccctt tccaagaatc caagccataa gaaaggatat
    18961 aaatctcaga aaaaccttgt tttttcaagt aaagagctgc atttgtaact cgttgcgcac
    19021 gttggttctc gtagagaagg acaggtttat ctttacgaag ggctgcaaga ctagttttca
    19081 actgacttga aggaatattg cgtgcaccaa ggatatgttt tctgtggaat tctgctgggt
    19141 cgcgcaaatc aatcaattga cccgtacgaa tcaaggcttc aaactcctca ttgtccacaa
    19201 ttttagccgc acgacgaata cgaagatagt taaagcccat ccacgccaac attgctagta
    19261 taagtgccca caaaatccaa gtaaccatta gttcttttct ccatttttct caatataatc
    19321 caattctacc ttgtgctctc tgcgaagaac tgcttctgcc tctagatagt ctaatttatc
    19381 catcaaccct gcatcgtaaa tccgagatag ttccaacttc atcagttcaa tatcatataa
    19441 gcgttttccc atgtaaacaa taataccaaa tcgtttgagg aattgctgca catcatagaa
    19501 tgttttcata agactcattc tagcaaaatt ttgtgttttt ttcaagaaga gactcacaca
    19561 atgctcctta ttttcctatc ttctttggcg attctaaggc aagtgtggta caataaaaac
    19621 atgagaattc aacaattaca ttatattatc aaaatcgtcg aaactggctc tatgaatgag
    19681 gcagccaagc aactctttat cactcagccc agtctctcca atgcagtgcg agatttggaa
    19741 aatgaaatgg gcattgaaat ctttatccgc aatcccaagg gtattacctt gacccgtgat
    19801 gggatggagt ttctctctta tgcccgtcag gttgtcgagc agacccagct tctggaggaa
    19861 cgctataaaa atcctgttgc ccaccgcgaa ctctttagcg tttcgtctca acactatgcc
    19921 tttgtggtca atgcctttgt ctctttgctc aagaaaagcg atatggagaa atacgaactc
    19981 ttccttcgtg aaactcggac ttgggagatt atcgacgacg tcaagaactt ccgcagtgag
    20041 gtcggggtcc tcttcttaaa cagttacaac cgtgatgttt taaccaagat gctggatgac
    20101 aatcacctgc tatcccacca tctcttcaca gcgcaaccgc atatctttgt cagcaagacc
    20161 aaccctctgg caaagaaaga caaggtgaaa ctgtctgatt tggagaattt cccttacctc
    20221 agctatgacc aagggacgca caactccttc tacttttcag aagagattct ttctcaagaa
    20281 caccacaaga aatccattgt ggtcagtgac cgtgccaccc tctttaatct cttgattggt
    20341 ttggatggtt ataccattgc gacagggatt ttgaacagca acctaaacgg agacaatatc
    20401 gtttctatcc cactggatat tgatgacccg attgagctgg tctatatcca gcatgagaaa
    20461 accagcctat ctaagatggg cgaacgcttt atcgactatc tactagaaga agttcagttt
    20521 gatagttgag aaatgataag aaccaatatg taggctagca acaacctgca cattggttct
    20581 ttttacttat aattaaaagt ttcccctgcc aacttatcag ctagcttggg aaagagagta
    20641 taaaacttat gggctaggtt caacaaaatc gggagattga gttctcgttt attttttcct
    20701 ataatcttga caatcttttt agccactgca tctgcctcta agaggaagcg gtcaaccgat
    20761 ttaagataag ttccatctgg gtcagcttgg tcaaaaaatc ctgttcggat tggacctgga
    20821 ttgactgttg tcacatagac tccatagggc ataagttcga gtcgcagagc atttgaaaaa
    20881 ccaatagccg caaacttggt cgctgagtaa agactagact tgccagtagc tattagacct
    20941 gccatgctga cgatgttgat gatatgccct ttgctgcttt ccttcatacg agccgcaagg
    21001 tgacgagaca gattcatcag ggcaaaggta ttgacctcaa acatctggtg aatgtcttta
    21061 tcagcaattt ggtcaaatcc ctcaaaaatc ccgtaaccag cgttgttaat caagacatca
    21121 atcttgccat agcggagata aagatcagtt accagagctt ctagggctga atcgtcggta
    21181 atatcaattt caatcaattc tgcatgggaa taatttccgt agagttgggc taatttttcc
    21241 ttatttctac caagcaagat gagttggtca ttgggcagga gtttgaccat ttcttgagct
    21301 agaccaccgc tagctccggt aatgagaata gtaggcatac ttatcctttc tgtgactgct
    21361 agatttccac ttcttccaag tctttgacca catggacatt ttcaaaaatt gtggcagcgt
    21421 ccttcttgag tttgcttata tcttttgaga ggaaacgggc actgatatgg ttgagtagga
    21481 ggcgtttggc acctgcttct accgctactt gtgcagcttg catattagtt gagtgaccat
    21541 ggttacgagc aattttttca tcacccttgc cataagtgga ctcatgaact aggacatctg
    21601 cattgacagc cagacgcaca ctggcatccg tttttcgagt gtctcctaaa atagtgataa
    21661 tcttacctgg acgtggcgct gagatatagt ctgctgcctt gatttcagtt ccgtcttcca
    21721 aaacaagatc ctggccgttt ttgattttac caaaaagcgg gccgaacgga acaccagcag
    21781 ccttgagttt ttcagcatcc agcgtccctt ctagatcctt ttgcatgaca cgatagccaa
    21841 cacagaaaat agtgtggtcc agctcctctg catacacagt gaatttatcg gtttcgagaa
    21901 ttttacccag agaatcttgg tcaaactcat ggaaatgaat gcggtagggc agacgagaac
    21961 ctgacacacg aaggctggtt aagacaaatg acttgattcc ttgaggtccg tagatttcca
    22021 aatctgtctg ctcttcattg gcctgaaagg cacggctaga aaggaaacct ggcaaaccaa
    22081 aaatgtggtc tccatgcaga tgagtaataa agattttgct gaccttacgt ggtcgaattg
    22141 tggtttccag aatgcgattt tgcgtacctt ctccacagtc aaagagccaa acttcgttaa
    22201 tctcgtccaa aagtttcagg gcgagacttg aaacgttgcg ggctttagag ggctgaccag
    22261 cccccgttcc taaaaattga atatccattc gatactttct aattaatcaa tatataacat
    22321 ggctgtgcgg ttttccgatc ggaaatagcg tttgccagaa aaagcagcag cttcttgcaa
    22381 taaatcctct tggctgtagc ctttgagacg ttttcgacca tcagccaatc tttccaaatc
    22441 agtcaaagct gtgagacttt ctaggctgac aacttcctcg tcctcgacag gcttcatgta
    22501 aatcttacca gactcttcaa agactaattg atgggggaaa atttgcgcaa tttcaaagag
    22561 caagtcatcc gagattttct cctcattttc agagaaaatc cgaccaaagc cgtcactctc
    22621 ataacaaaaa ccaaaggatt taccagacag attaagccga ataaaagact tattttctag
    22681 ggtgaaactt ggctcagtat tgtaaagatt cagttcctga ctgagttctg caaaataatc
    22741 cgtcgcagcc tgaggacttt ttttctgata gagttctgca aagtaggcat taacaacact
    22801 tggcggaggt gtaataagtg ttaactgctc ctgctctgtc ttaccagcta gaagctgatc
    22861 cagatagacc ttgtccagac ttgtataacc tccatacttt agagccaaag ttttaatatc
    22921 agtcataaaa ttcttctaac ctccatttat ttttctcgga aatgtagcct gtaatcactt
    22981 cgccgtcttc ctgataatca cgttcttcca gaattgcaac actctctaaa tcatgaatct
    23041 tgtaggactt tgaaaaaggc actcgcaggg taaatgcttc aaaaatttcc ttaatcttat
    23101 ctagcaataa tgcttgcaag ttttcacgac tgtcctcaga cttggcagaa atgagggtat
    23161 atggcgtttg ggtaggcatg aaatcctcca ccaaatccgc tttattataa agcgtcaagt
    23221 gaggaatatc ttccatgtcc aggtctttca tgatggagag aaccgttttt tcatgttcct
    23281 cgtggtaagg attgctagca tcgataacat gaaccagaag gtccacatgc ttgctttctt
    23341 ccaaggttga cttgaaactg gacaccaact ctgtcggcaa atcttggata aagccaacgg
    23401 tatctgtcaa agttacttgg aggttgcctc ccagatgaat actcttggtt gtcgcatcca
    23461 gagtcgcaaa gagctcatct gcttcatact gggtcttact ggtcaagatg ttcatgatag
    23521 ttgatttccc agcattagta taaccaatca aaccaatctt aaaagtgcta gactccaaac
    23581 gtttttctct gacagtcgca cgatttttct caaccacctt aagctggcgc tcgatatccg
    23641 tgatttgatt gcgaacgcta cgacggttca gctccagttg gctttcacca ggaccacggg
    23701 aaccaattcc ccctgcctga cggctgagca taatcccctg accaaccaag cgaggcaaga
    23761 ggtatttgag ttgggctagg tggacttgga gcttcccttc atggcttcga gcccgcatgg
    23821 caaagatatc caaaatcaac tgcatacggt caatgacctt aacaccgaga acttcctcta
    23881 gattgacatt ctgccttggg gtcagacggt tgttgacgat gacagtagtg atttcttctg
    23941 catccaccat aagcgcaatc tcttccaact taccagagcc gacgaaggtc ttggaatcat
    24001 atttttcacg tttttgtctg tagctatcta caacgactgc ccctgccgtt ttcgctaaac
    24061 tagccaattc ttccatggag aggtcaaaac tgtccatacc ctgcaattcc acaccaatca
    24121 gcaggactcg ctcctctttt ttctccgttt caatcatcta aaaactcctc tatctggctt
    24181 aaaatgcggt cttgtacacc agattctcca atctgataaa aggtgacctg catgcgatta
    24241 cggaaccagg tcagctgacg cttggcaaaa cgacgggtcg cctgtttaag actctcacga
    24301 gcttcctcca aggtctgctc tccacggaaa taaggaaaga gttccttata gccaattcct
    24361 ttagcagcct gtacattagg ggaatggtca aacagccact tggcctcatc caaaagccca
    24421 gcctcaaaca tcaaatccac tcggtggttg atacgctcat aaagttgact acgttcatca
    24481 tccaagcaga taatcagcgg ttcatacaaa atctcttgat tttccaaatc ctgaccaaaa
    24541 tgggcaattt ctaaggcacg catagcacga cgacgattaa actggggaat ctcaaggcct
    24601 gcttgctcca ccaaatgggc taattcctca tctgaatatg gctccaaact agctcgataa
    24661 gctaaaatct cctcatgagg agtctcccca cctaggtggt aaccttctag caagctctgg
    24721 atataaagtc cagtcccacc ggcgataatg gctagcttgc cacggttgtg aataccctca
    24781 atagtcatct tagcttctga aacaaaatca aaagccgagt aagactcggt tatctctcta
    24841 acatcgatta aatgatgagg aacagctgcc tgctcttctg gactagcctt ggccgtccca
    24901 atatcaagtc ctcgatagac ttgctggcta tctccactaa ccacttcgcc attaaaacgc
    24961 tttgcaactt caatagctag agccgtcttt ccaacagcag tcggtccaac aatcacaatt
    25021 atttttgttt tcatcttttt tccttgaaaa attcccattt tttcgttact attattataa
    25081 cacaaaaagg tcagtcagaa aaatgtgacc tcttgaggag gctggctgat tgagaatata
    25141 aaggaggaag actcatggct aaaggattcg ctaaaggtct tgtaacaggt gtcgcaggaa
    25201 ctgtcgctgc cgttgcaggt gcagtatacg catttaaaaa gaaagtaatc gaaccagaag
    25261 agcaaaaagc agctttcatc gaagaaaacc gtaaaaaagc agctcgtcgc cgcgtatcac
    25321 gttaagaaac aaaagaagtt gggattattc tcaacttctt ttttctattc ttttaaatag
    25381 ctaggtcaaa cttcaactgt ggcttaacag ggtcataatc caccaactca aaatcttctg
    25441 ctttgatatc aaagaaatta gtcccatcag gaacatttaa aaccaagcgt ggttggcagt
    25501 ttgacggctc ccgacggagc aattcctgag cttgttcaaa ttgattatca tagatatgga
    25561 ggttgttgat gaagtagaag aacttcccaa ccttccagcc aaaatgtttg gcaatcatca
    25621 tctgcaaagc cacatactgc atagcgttga tgtggtgggc caccagcata tcattggagc
    25681 gctgggtcaa ggtcgcatcc agatagattt ccccatcaac acgccggaca tcaaacatgg
    25741 tctgaaaggc gcacgggagc agcccatctg tttcttcgaa agcttggtaa tcccagagcg
    25801 aaataatatt gcggcggttc caaggattgg tttccaactg tttgagaagc ttattgataa
    25861 tgtcgtgttt cttaacaacg gcaccatagc gctcaccaat ggttcccgtg tctccaactt
    25921 cccagtcatt ccagtagtga acattgtact tgtcattaag cacttctaag ctatttgact
    25981 ggtcttggta aatccagaga acttctttga tggcggattt gattgcaatg ggacgcaagg
    26041 ttgtgatagg aaattctcct ttagataagt cgtactcgga aaaggcacca gttacatact
    26101 tggaattagc aacagtccca tccttgtact taggacgagc ctgctctgag aaaacacctt
    26161 cctttagaat gcgttcaata ttctctttaa aaatcgtatc tgcttttgtc atttcgtttc
    26221 acctcattca ttgtcctaac tagtatagca taaaaaataa aagaggaaca ttactaactc
    26281 taggttagca ttttcctctc tcattatctt attgcaatac aagtgatgct gctccgataa
    26341 ctccagcgtc atttcctaga gttgcaagag ctaatttagt agatgtgcgt acttgtggga
    26401 aactattttc atcgtaaact ttttgaacac cttgtagaag gaattctccc gcagctgaca
    26461 caccaccacc gatgacgatt gttgatgggt ttaggattga accaatgtta gcacaagcga
    26521 ttcccaagta acgtgagaag ttacggtaaa caatcaaagc aaggtcgtct ccttcttttg
    26581 cgagatcaaa gacagtctta gcagttactt cttctccgtt atcaatcaag cgtttcaagg
    26641 ctgcatcgcc ttcgtattca tcggcatagc gacgagtcaa gttgacaatc cctgttgctg
    26701 aagcaactgt ctcaaggcag cctttcttac cgcaagtaca tgcgattggc tggtcaaagt
    26761 caacagtgat gtgaccaagc tcacctgctg caccagcaac accgtgaagc aatttgcctt
    26821 ctgcgacgat accgccacca acaccagtac cgagtgtcat aaagacaacg tctggttggt
    26881 tatctccagc acccatccag cgctcaccaa gagctgctac gttggcatca ttatcgatga
    26941 aaaatggaat gcccaaagct ttttcaatct tttgtttgat tggttgaagg gttttccagt
    27001 tcaagttgta ggcaccgata acagtccctt tttcacggtc aaccacacct ggtgatccca
    27061 ttccaatgcc ttggaagtcc gctgctgcca atccaagcaa gtccaaacga tgttgaatag
    27121 actcaatcat atcatcaacg atatgacttc cctcatccaa aatgtttgtc ttgattgacc
    27181 attttccttg gatttctcct gctgttgtta agattgcaaa tttgatagaa gttccaccaa
    27241 ggtcaatccc aataatcttt tgactcatca tattctcctt tttcattgtg tagtaattga
    27301 aaatgcttac agtactagta tatcaaaatc cattcactta tgcaaaggtt tgcgtaaatg
    27361 aattataagg aattttttcg cctaccagta tctgttaatc atctaaatga tcaatggcat
    27421 attgagctgc atcatttgaa aatttatcaa aatcagaagt taattgtcta tacatacgtt
    27481 tttttgacat gtggaataac gaattataac tttttgcctt tcctaaagca gcagaatatt
    27541 cactattgct atcattacta gaagaaactg tacttgcttg accttccttc caaactccgt
    27601 cagcgccaac ataataacgt ccaccatcaa cccattcatt gacagccatt ttaccattcg
    27661 attttagata gtaatttcct tgccatgtac tgtaagcata agaaccatct gatgtcaaat
    27721 aataccaagc ttgataggtg gcatcataaa cccattcacc tttagccatt ttaccatctg
    27781 atttcaaata gtagtttcct tgccatgcat tgcgagcata tgaaccatct gatttcaagt
    27841 aataccatgc ttggtaagaa gaatcataaa cccactcacc ttgtgccatt ttaccgtttg
    27901 atttaaggta ataagctcct tgccatgcat tttttgcata agaaccatct gatttcaaat
    27961 aataccaagc ttgataagaa gagtcataaa tccattcact ctgtgccatt ttaccatcag
    28021 ctttcaggta atagcttccc tgccatgcat ttttcactag atttccattt ccatcaaagt
    28081 agtaccaagc gccgtcctgc ttaacccaac cacttgttgt tgctgaactt gtgttgattt
    28141 gaatagccgt tgactgtttt gctttaaaag cacccttagg agcatttttc aattcgcaag
    28201 ccacaccatc atgatcacgg tctaacttgg cagaataacc aggttctccc tcgtgaatat
    28261 ccgaatagcc attcgcccaa gcttccttac agctcgaaaa atggatgttt tcttccgcca
    28321 aaactggttg tgaaaacaag gctaaaattg gcaacgtcac cagactcatt tttaaaaata
    28381 gacgtttatt catttctttc tcccataatt atgatatcga tttcaatatt attttatcaa
    28441 acttatttca gcaattcaag gaaacttctg gtcttttcta caaactcctt tggttttgcc
    28501 ttattcaaga catgagggcc atcaggaatg atctgaaact gcgaatctgt taacagtcta
    28561 tggagagctt tcatagaact aagattcggt ttatctttgc tgccacaaat tagtaaggtt
    28621 ggataggagc aagtccctgc tatatccgtt aaatcaagtg tcttcaattc ctcagaaact
    28681 ccgaccataa gagtcttgtc tgctccctgt ttttcaaata ctcttttggg aagtagttta
    28741 aaaatcagca actgaagata aaataggata ttccctgcta atttaagcgg gcatcctgac
    28801 agaatcaaag ctcgaagatt tggtaaatcg taactggaaa gttctagtgt cagggcagca
    28861 cctaaggaca atccaatcaa aacaaaaggt tctgtctctt gagctaggtg ctgataaact
    28921 cgctctttag cttgttgata gttactaact ccagaaggaa ataactcgat agcctcagaa
    28981 ggataatctg tcagtagatt ccgaacttct ttccaagact ctgctgactg ctctaaccca
    29041 tgcaaaaata tcaatttcat ctagttctcc tcaaggctta gttcatacaa gcctctcact
    29101 gcattacagc cgtaaatagc ttctgcttgg gttaaatctg ccaaggtcaa gactttctct
    29161 tctacctgtc ctgtttctag caaatgctga cggtaaattc ctggcaagat tccaagtcgg
    29221 ataggcggtg tgtagagttt tccagcgatt ttcagaacca aatttcctat agaggtttca
    29281 agcagttctc ctgacttatt gtggtaaatc ttctcttgtt ctcctaggct caaatgcggt
    29341 cggtgagtgg ttttaaagta ggtaaaggat tgattcaaag cagcttcctg aaggcagact
    29401 tgggcctgac aaaagcttgt actgagaggg gttaatactt gacgattgac ttctatctct
    29461 ccagatttgc taaggctgat tcgcaagcgg taatcttgat tagcttcaca atcctgacac
    29521 tcttcctcaa tcttgtgtcc caagtcttct gcatcaaaag gaaaggcaaa ataacgacta
    29581 gcttttctca gtctttccag atgttgatct tcaaacagca ggttcttctg gctgatttcc
    29641 cctgtcgtaa tcagttggaa gcgagcttgt ttacgataaa gaactgctgc cttttgatga
    29701 acctctcggt attcagattc ccatgtgcta tcccaagtaa tccctccgcc aactccataa
    29761 atggcttgac ctttgtgaag ttgaatggta cgaatggcca cattaaaaat ccgtcgtcca
    29821 tttggaagca agagaccaat cgttccacag tagactccac gcggttgagg ctccaagttc
    29881 ttgataatct ccattgtcgc aattttcggt gcacccgtta tggaaccaca aggaaagagt
    29941 gagcggaaga tttcaacaag gtccacatcc tctcgcaact gactcttgat ggtcgaagtc
    30001 atctgccaaa cagttgaata ctgctctacc tggcacagac gctccacgtg ctcgctccca
    30061 acttcagaaa tacggttcat atcattgcgc aagaggtcca caatcatcat attttcagag
    30121 cgatttttgg gatcctgttc caaccaactg gcctgttcaa gatcttcttg gtcagttacc
    30181 ccacgctgag tcgtcccctt cattggtcgt gttgtcaact cgcgatcatt ttgctcaaaa
    30241 aagagctctg ggctcatgga aatcactgcc atctcgtcat gttccacata ggcattgtag
    30301 cccgcctcct gctctaccac catacgattg tagatggcaa aaggattggc acttaacttt
    30361 tgcttgagtt ggacggtgta gttgacctga taggtgtctc cctgcctcaa gtgatggtgt
    30421 atctgggcaa tggccttttc atagtctgct gcagacgtca cttcctgcca atttgagggc
    30481 aaatcaatat cctcataagt cagaggaata ggggaagttt ctacgctatc atgaacagta
    30541 aagtaaagca ggtactctcc cagtagggga tccttgtgaa ctgctaattt ttcctcaaaa
    30601 gcaggtgcag cctcgtagct gacatacccc accacataat aaccttgctc ttggtagctt
    30661 tccacttgtg ccagcaaatc tgccacttct tctacatttc tcgttttcaa ctctttaata
    30721 ggctgggcaa aggtatatct ctcccctaaa gtcctaaaat caatcactgt ttttctatgc
    30781 ataccttaag tatagcataa aaaggcagat acagacaaag ctgatctacc tttttacgat
    30841 tttattcatt ctatgcttgt ggtgcagtaa atagatcacc agagaaaccg tctgtgtttt
    30901 taaggagaga tttaaagact ttcgatttca agacaactgt atttcggtat ttgtctttaa
    30961 tactactatc gtttagttcc gttaaatctt tagtaacagc ctcatcaaac atagtcttca
    31021 actgttcata ggttgaaatt tgagtgccat taatttcaat tggtgcaaaa ccttttttag
    31081 attttgtaag aacttcccca taccattgct tcttccaatc ttcaaggttt gaaaattggt
    31141 tattagaaac tttcttaata atgaaatcat cacctaatag accgttattt tctttattgg
    31201 ctgcaccttg atgtttgctt gaaacatagt caatgaaccc atgttcatat ccatagtaac
    31261 cccacatacg gaaggcgtta tgtttgaagg atagagaacc aggggcacct tgactcgtat
    31321 taccgccata aataccagcc atcatattaa cattgacata tgccgtacca aagtcctctg
    31381 ggtggaagac cttattacct ggatttccgt gaatggtcat gaaattatta tttaccaagt
    31441 catcgatggt ttcaaggtta gttgttttct cagcgtctat caaatcacgc actttgtccc
    31501 attggtgagg accacttagt ttatttctgt ccattggtcg acgtgtttcg cgatcaattt
    31561 tcttgaacca cttactattg tcacctttaa ccttaggaag aacagcctca gcttctgcat
    31621 aatcgagcat catcatagct tcattgtagt tcttcatgta atggtcgatt tggtcacgtg
    31681 tttgaagttt ggtaggatct ggattatacc attggtttcc atcatttgaa cgttcaaatg
    31741 ccatatttaa tccaagtgcg ccatattcac cttgatgtcc atgttctgct ggagtttgta
    31801 acataccttg agcaaatgct tcaagatctg taccctgtcg atgtctatga cctcccagat
    31861 atgccattcg gtcatttacg tgggtagtct catgtgtaaa ggcagatgtg ccatattcac
    31921 ttattaaatc cgacataaca aaatatacag catccatagg ctgtggatca gcaaagatgt
    31981 aagcatacgc tccataccca tacttataat catgatactt atcaatacgt ccaaagaatt
    32041 cacgaatagg tgcataatcc ggtttatctt ttcgatgacc aaatctatca ggccaaccac
    32101 cgggtgcacc atgattatcc catacaggag ttggaactac attttgactc ttaagaagtt
    32161 tatcgcggac attatcagtg gcaaggcgtg accaaaaatc taagtaatta acttgctctt
    32221 tagcacgttt attgatttca ctcttgaacg cttcacgttt ttcttctgta tctttaccat
    32281 acttttcaaa cgaactaaat gagatagtat tatatgttga aatcataaat aaatgtgcat
    32341 ctttcaagtt cagaagcgat aaaatcatgc gtccatgttg tccgttatta agtccttcat
    32401 atagacgata ttttttatta gcaaatgcag ggttagttga cggttgttca actacataag
    32461 cattattttc aatagctttc ttaaaccaaa catttatgtc tgtttcattt gtgaatagtt
    32521 tcatattgta ggtcaagaag tcatgtaagt ttccagaaag agtatttttc gccaccactt
    32581 cacggaagga ctcctgtgta cgacttccct taatatagtc ctcttttgaa ccaatttcta
    32641 ttaatcgatc taaaacactt acattcttac cataaaaatc tggtttgaat agcattaatt
    32701 ctttaatatt gaagttatca aatttcacac cgtaataacg atttaggtat gttaatccta
    32761 acaggacagc agctttgtta tcttcaattt tcttaatcaa ggcacgtttt gcagcttcat
    32821 ctgtattcag ttgatgatct tcattttcaa ctaattttgt cacaaatgta ttaagatgat
    32881 cttttacttc tttaaagctt tcttctaagt aaagattctt aattgcatta actctgttat
    32941 ccccagttct tcctaatcgt tgataaattg gatcagattg taattcaatt ggacttaaaa
    33001 taccttcaat agcactaatt aaatctgcac gatctttaac aaccatattt ggtgtataga
    33061 cgacttcacc aagctctgcg acactgtatt cttttacttg cttaacttga gagtctttag
    33121 gagaaatcgt aaagatatct tttgtcttat ctgcgtaatg aaccataata tggtcagcat
    33181 ctgtaaggtc tgtaataaag tcattacctt tcattgcagt cacagacaat acttctttat
    33241 tcattaatgg actatcagtt gtaagcttgt tcccttgatt cacaatccat tctttgttgt
    33301 agaacggttg gagtttttca acattacgat aaacaagctc acgatttgca ttataatctt
    33361 gaattgtttt gtattcttca tcacgtaata tacggcgatt caacttatca accaaatgct
    33421 cagttacttc aaatgtatca gcagtgatac ccatatcctt aattttctta tcagcttcta
    33481 cctgtgaaat ttctttaatt ttagacgatt gtttatgggt tttatctcca gaactcacac
    33541 cgataactgt tgcattatta ggtttaatcc aattgcttac aaattcatca tccatatcat
    33601 tagaaccaaa gaaaatatca ccacgcttaa cattcactaa gctgatattg ttatcaatgg
    33661 ttccccaagg ccagtcttta ccaattaaac cgcctacatc acctctagca acatcaatag
    33721 tacctttggc tacagaattt cttacattag accaagcacc aacatctctt ggattaaaat
    33781 catgagctaa atgtcctact atagcacctg cacgagtatt taaaccttta agttcaacat
    33841 ctgcataagc tttatttaaa ttgcctcgat aaatctcaga tgcaatccca gccaagttcc
    33901 accctttatc accaacagat tgaacttttc cgataaaagc aacattagtc ataatacctg
    33961 catcatctaa tttatccaaa atacccgcaa cattgttatt accaacgata gtacccgtta
    34021 ctttaatatt ttcaacagtt gcatttttca ctgtttgagc taatgaagct aattgatttg
    34081 cccaaggcat attaatatta acgttaatta aattaatatt tttgatagaa cccccttcaa
    34141 ctctatcaaa taatggacga gcagtgttat gaatggagaa atgcttacca tcaacacttg
    34201 ttaagtgacc tgtaaattta cctgttacat atgatttact tggtgtaggt acatttgttg
    34261 catttaaatc cgatcctaat ttaaactcac cgttaggatt tttctgcata gcatctacta
    34321 aatctttgaa gttatagtaa acgttatttt gcgatgcttt gggtttctct atgtaataag
    34381 tgtatgtttg actcaaacta ttatttgaat cacgttggat taaatcagga gctgaagcag
    34441 taactttaaa taaggatgtc tcctcctcag ttacttcctc tatattagta atggcaagcc
    34501 ttgttacttt attatgatta gtggtaattt ttagataata tgacgttaga ttttctggaa
    34561 cagtttctag aaggctacta tctgtttcat ttccattctc atccactttc atcaatcttg
    34621 tttctttaat atctttaatc tcaacttttt taaggtctaa ctgaacttct ttatcttcta
    34681 atatttcagt ttcttcaccg ttacctcgat catagaccat ggttgtggat agtgtataac
    34741 cttgataata tttcaagttg tctaaagtag cttgtaagtt attttcttct accgttactt
    34801 ctttaacaac tgttccagta ttatctttta gagctacttt aatcgattta atttctactc
    34861 cagctggttt agtcaatgta taactagctg tcgcactctt cttcaagaca tctttatctg
    34921 ttttagccca ttccaaggtt ggtttctcta actcttttgt gccattctta ataattttgt
    34981 cttgaggttt ttcaatcact gtttctgtga tagtaggagc ggcacttgtt ttttctccgc
    35041 gaattgtttt ataggtttca gtaatttgtt tcttatcgtt tacaccttct tgagttactt
    35101 gtcttgttcc gcgttttaaa gtgtcatctt cttgttcttt tgtttcaaaa ggaatgattt
    35161 cttctcttgt ctcaaccgtt gtcccttcaa ttggttttgt accacggatt acctgttgat
    35221 ttacaggctc cttggtgact tccgtactgg ttgaaagaac ttggtcagtt tcaacccctc
    35281 ctattgtttt ataggttgtt tttgtaactt gacttccttt ttcaccattt cgtaggacag
    35341 tttcttcgtc cgtgtacttg gttgggtcct cagtcgtttc agttttatag tcaagttctg
    35401 tagttgattc ttcaacgagt gttccttcag tcaccttata ctcaggtaat tgttctggaa
    35461 caagagcctc acccacgtaa tcttcttctt gcgtcccctt agctgtttta gtctcctctt
    35521 ttggttctac agtttcttca gccttggtat ctggagttga ctcttcttgt ttcggtgtct
    35581 cttccgctcc cctatcttct ttaggatttt cttgttgtga tgtttctttt ggtgtacttg
    35641 gttgctcagc ttgtgtaggt tgcacgggtt gttctgggac ttttgcttgt tctactggtg
    35701 gttcaacttt tgattcctca gctggtttgt ctgatggttg actttctggc ttaactgcta
    35761 ctttttcctc tggttttgac tcaacttctc cacctacttc ttcaactgga gctggttctg
    35821 ctgaatcttc tttcccctct tctactttag gaagggtgtc gtcagtaggt tttacctccg
    35881 attttggttc ttcctttgga ctttcttctg ttttaggtgc ttcttctttt ggagcttcct
    35941 ctgtctctac tacttggttt tctgtcctag cttgctcctg atttgttatt gattgaggag
    36001 tctcaacttc gactacagtc acctctccag gttttgctga ggtttcttct aaaacagtgt
    36061 ccaagccaag cgttttgagg atgtcacctg atagataacc aacatagcga tagccctcca
    36121 tttcaacaac accctctcga ctagccagcg ctagggtcgc aactgggtct acagcccctg
    36181 cactaggaag aactaccaat cccatagctc caactagaaa gacgctagca attttctttc
    36241 tcttgtagat taaaagcaag ctcccaacag tcagcaaacc aaaagctgtc aaaacagatg
    36301 cttctgtccc tgtttgaggc aactgatctt tttgatacac caaaccatat acaacttcat
    36361 tcctgtcagg ctttcctgtc tgaattaaat ctttagcttc ttgtgaaata atctctttat
    36421 ttacatagtg ataggtggct gcgtccacta cagaaggagc catcaaaagg cttccaagaa
    36481 atacagagcc tacaactccc ttaatcttac gaattgaaaa acggtctttt ttaaacactt
    36541 ttatctcctt tattcattct caagactttc taatagcgtc ttgcggatag tgcgcacgcg
    36601 cacctccgat taattttgga cgactagcca gtgccgttac atgggcatga ccaatctctc
    36661 tcaaaatagg gcgaatcgga acctgaacat gcttgacatg catgccaatt gcagtgtctc
    36721 cgatatccaa tccagcatga gccttgataa attcaacctc aactggatcc tgcataaact
    36781 taaaggctgc caactgcccc gaacctcctg catgaagagt aggatggaca ctgacaattt
    36841 ccagaccaaa ctgctctgcc acctgacgtt caacaacgag agcccgattg acatgctcac
    36901 aaccttgaac tgctaaatgg atacctctac tacttagaat acccaagata gtctccacta
    36961 tcagctcacc aatctcttga ctggattctt tcccaatctg accacctagc acctcactag
    37021 aagatagacc taaaacaaaa agggccccct gcttcaaatt ggtcttttct aaaacatctt
    37081 ccactacctg acgtgtttct ctttgaatct gtgtctcgtt catctctgtt acctctgttg
    37141 tcactcttct atcataccgt tttttcttgt ttttagcaag atagacaacc tagaaagttt
    37201 gcccaattac gcataaaact cccagaattg actgggagtt agctagtttc tattctattt
    37261 atatatattt caactttcgt ccctttttgg ggtctagaat caatcttcat ctggtaattg
    37321 gctccaaaat gaagtttgag ccgttgatcg acattttgaa gaccaactcc cccacgtttg
    37381 agttgacttt gactactatc accagcatct tggaagccaa cgccatcatc ctcaatacgg
    37441 atgaccaatc ccgaatcctg tttctggaca gaaagtttaa tatggccctg accttccttt
    37501 tccttaatgc catggtaaag agcattttct acaaggggtt gtaggaccag cttgggtaag
    37561 actaaattat caaaggtaac attttcatta atttcgtatt ccagcttatc tccatagcgt
    37621 tgtttctgga taaagagata ctggcggaca tgattgattt cgtcagagag acaaatcaag
    37681 tccttgcctt gattgagcgc caagcggaaa taggttgcca aggacttggt cacctgcacc
    37741 actcgctgac tatcatgaaa ttcagccatc cagatgatgg tgtccaaagt gttatagagg
    37801 aaatgtggat taatctggct cgaaagggct tgaagttggt actgacgggt cgtttcttcc
    37861 tggctacgaa tagctaccat caactgatca atctgatcca acatggcatt aaattggcga
    37921 gttacttctc tcagttcata ggcaccaact tccttggcac gaagattttg agcaccagaa
    37981 gcaatttcca acatggtttc tctcaaatcc ttcaaaggag caatccagcg tttaagactg
    38041 aaccacacta agcagagaca gacaagaaga gatgtgacac tggccccaag caaggtccac
    38101 aagagctgac tccgaacctg gtctaacttt tccaatgatg acacgccaag taccgtccaa
    38161 tcagttcctg caatcttctc ttgactgacg taggatttgt gaccaggagt ataaccctga
    38221 cctgtatcga tgtagggttt catagcctcc attttgctag acgaactata aactgtgtgt
    38281 tgaggatggt agacaaattc atggttttca ttgataatga aggcaaagcc ctgctgcccc
    38341 aactggagtt gattgagata ggcttccaga gtttcataag aaatatccaa acgaagcaca
    38401 ccaagattgg ctccctttgc atcaacaagt tcttgagtga cagaaatgac ccactgacta
    38461 tctgatttac gagctggagt caaaacaggc atagctccct gatgaatggc cttttggtac
    38521 caatcctcag ccatcatatc agaggaagtt ttcatctgca cactgtcatc tgtagaaatg
    38581 acctgaccag atttggtcac cagcacaaca gttttcaagt ccttatctga cttcaagatg
    38641 gtcaaaaaca aatctcggat tccctcgacc ttgtcttgac tgggattctc agcataggcc
    38701 agaacatccg tctgctgggt caaaccggtc gaagtggttt ctagtttttt gatataagac
    38761 tgaataaagt ggctagtctg gctgatggtc gtttggctgt tgccctcaat ggtggcctca
    38821 atggctgaag aacttgattg atagtagaaa gttccaacca gagctaggag aatgagaaag
    38881 accagaaaga tggaaataac cattctaact aaaagagaag aacgcttcat cggtcttctc
    38941 ccttcttaaa ctgacgaggt gtcacacctg caatctgctt aaaacgttgg gtaaaatagt
    39001 tcatatcttc aaaaccaacc ttctctgcga tctcataaat cttcagatct gtagttaaaa
    39061 gcaagagctt ggcttgttta acacgttctc tcaccagata atcctgaaaa ggcaagccca
    39121 actctttctt aatcaaggaa ctcagatagg tcggactaaa acctaagtca ctggctaaag
    39181 actttaaact aaattggcta tcagccagat gagactggat tttctgggcc atgtttcctt
    39241 caaacctatt agtcaataaa tcttgtaact gctcttcttt ctcttccttg tctagttttt
    39301 gtttgatttt ccccaacatt tcctcaatat cctgacgaga aaagggtttg agcaggtagt
    39361 cgtccacacc tagtttgaca gcagacaagg cataatcaaa atcatcgtaa cctgttaaaa
    39421 agaccaaatg aacctgagga taggtttctc gtaccagact ggccaactgg atgccattta
    39481 gatgaggcat gttgatatcg gttaaaatga tatctggcac ctgcttttgg atcaattccc
    39541 aagcctgcct tccattttca gcctgaccga tgatttccat atcgtaggct gctacattga
    39601 ccagtttagt caaaccttgt cttaccagat attcatcttc tacgattaag attgtgtagg
    39661 tcatgatctg ctcctttacc acttactagt atcagtatag caaaattctc ctctaactgc
    39721 ttaggaaaga cctcttatac tcaataaaaa tcaaaaagta aactaggaag atagccacag
    39781 gtttctcaaa gtaccgcttt gaggttgtag ataaaactga cgaagtcagt aaccctacat
    39841 acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa tcaacataat
    39901 ctagtaaata agcgtagcct ttttcttcca tttggtcttt gggaataaag cggatagaga
    39961 ggctattgat acagtaacgt aagccgccct tgtcctgtgg accatccgta aagacatgcc
    40021 caaggtgaga atctcctact cggctccgca cttccatacg cgtcatattg taggacttat
    40081 cttccttgta ggtgacaaca tctggactga tgggttgggt aaaactaggc cagccacaac
    40141 cagactcaaa tttgtctttt gatgaaaaga gaggttcccc agttgctata tccacataga
    40201 taccggattc aaatttatcc cagtaacggt ttgagaaagc tcgttctgtt tgattttcct
    40261 gggtaactgc atactcctca ggtgacaggg tctttttcaa ttcctcatca cttggttttg
    40321 gatatttgct ggcatcaatg acaggatagg ccgcctgatt aacattgata tggcagtagc
    40381 catttggatt tttcttgaga tagtcttgat ggtaatcctc agccaccaca aaattcttca
    40441 agttttcctt ttcaactgct agaggttgat cgtatttctt agccacctca tcaaagactt
    40501 ggttaatcac ttccaaatcc ttgtcatctg tgtaataaac accagtacgg tactgggtcc
    40561 ccacatcatt tccttgttta tttttgctgg ttggattgat aatgcggaaa tagtgaagca
    40621 ggatttcctt gagagaaatt tgcttggcat cataggtgac atggacggtt tctgcatgac
    40681 ctgtttggtt aatcaattcg tacttggttg tttctcctct accatttgca tagcctgaaa
    40741 cggcatccgt caccccggga acgcgtgaga aatattcctc cactccccag aaacaacctc
    40801 cagctagata aatttcgtgc aagtctgcgt ctttactaat ttctgttttt ttcactgctt
    40861 ttcctccttg gctaactgcc gccttttcaa tttgcgaggc atctgtctgc cctgcatttc
    40921 gtatcaatag aacatagaaa ccggttatgg ctagaaaaaa tactcctagc aacaagaaga
    40981 tttttaactt atcattcata agacacctcc taggctaatt ccttcaaagt ttgcaaaatt
    41041 gcatcttttt ccatgaatcc tggatgtgtt ttgaccagct tgccttcttt gtctataaag
    41101 gcttgggttg ggtaagaacg gacaccataa gtttccaaaa gtttgcctga tgggtcaact
    41161 aggactggga gatttttata atccaatccc ttataccaat tcttaaagtc cgcttcagat
    41221 tgctctccct tatgtcctgg tgacactact gtcaagacca catagtcatc accagcttct
    41281 ttagcaattt catccgtatc tggaagacta gccagacaga tagaacacca agaagcccag
    41341 aatttgagat agactttctt gcccttgtaa tcagataaac ggtaggtctt gccatctact
    41401 cccatcaatt caaaatcagc cacctctttc cctttagctg cgcttgtttt actagctgtc
    41461 tgctccgtct tcatttcatc tttcgtttgg tgttcactag tcacggactt gcctgaacaa
    41521 gccgtcaacc aaaggagcga acctgctcca agaacacatg tttgccattt tttcatattg
    41581 atattccttt ccattttatt caaataattg acttaaaatt gaagcatttc caaacagaac
    41641 caagagtccc atcacaataa tgagaaaacc acccactttt ttgaggattc cgagataggg
    41701 atgaagtttt cggaaatgtt tcaaaacata actagaggtc agagctagaa gcaagaatgg
    41761 tagcgccaag cccagcgtat acaccaacat gagaccagct ccctgccaag ctcctgaacc
    41821 acctgaagcc gccaaggcca aaacagaccc cagaaccggc cccacgcaag gcgtccaagc
    41881 aaaactaaag gtcaagccca ataaaaatgc ctgactatag cccttaccat tttgcccctg
    41941 tccttgcagt tgtagcctct tttccttata aagcccctta aagtgtagaa tctccatttg
    42001 gtgcaaacca agaaggataa taattgcccc agtaagatat tggaaccaag aagcataaag
    42061 caaatcgcct aaaaaaccag ctccatagcc caacaaaata aatataaagg aaattcctgc
    42121 tataaaggcc agagttcgta ataaactagt aactgagatt gaaaatttgc cgctagaagc
    42181 ctgagcacca tccttatcat ctagtaacac tcctgtatag accggtaaca aaggtaagat
    42241 acaaggagaa aagaaggata gaatccctgc caaaaagaca cttagaaaaa agaaaatatg
    42301 acccataaag ttcctcctat cattttattg atagatttat tatactcctt ccattttcga
    42361 aaaaacaggg acaatgatag gggaaaatag gaatttaatc agatgattta gaaatcttgg
    42421 acaaaaacta tacaaaaaac tgtcaaagca caaaagcgca tagtatcaag attctataaa
    42481 gccttgatac tatgcgcttt tgtaatggat aaatagttag tcttttttaa agaccggatc
    42541 tttcaaactc tgcatactgg cattgatcac cgcgcctagg ataacaattt tagcaatcaa
    42601 gataaaccaa aacatcataa caacaagaag aacggaacct aaaattcgga catccaccaa
    42661 atgatggaca tagtaattga gataactaga gaacagagtt agtaaaccta aaatcactaa
    42721 gagaacaaag gcactgcctg gtagggtata gctaattttc ctgttagata gattgggaag
    42781 aaaataataa agcatgacca agatagcaaa gaggagggcg taaatcagag gacctgccaa
    42841 cccttgtaaa gcctgataga taatgccatc ttttgtccaa taatgagcaa gtaaagccaa
    42901 aatcatctga ccaaataaga tcaaaaacaa ggcaaacgca aagaggagct gcaagccaaa
    42961 actgactagg agacttagca tctgatggga aataagtcca cgactctttt cgacgccata
    43021 agccttgtta aaagcttttt gcaagaaatt catagatttt gaaaaactcc ataacgccga
    43081 taaaacagaa aaactcaata aacctgttga aggttgcgtc aagacttctc tggctatttt
    43141 ttccacacct tcatagaggc ttgggggcag gacgtctttc ataaagccca gaaattctcc
    43201 cacaggaatc tgaaaatagg ggaggatatt gaccaccacc aaaagcaggg ggaaaatcga
    43261 aatcaaccaa tagtaggcta ctgcgacact ggtcaactca ctatctgatg cttgataata
    43321 atgcaaaaaa gcttttaata aaggcttgtc tatcagctct ttccaccact ttttcatgtc
    43381 atactccttc atttataatc ttatactcaa tgaaaatcaa agagcaaact agaaagctag
    43441 ccgcaggctg ctcaaaacac tgttttgagg ttgtagataa gactgacgaa gtcagtcaca
    43501 tatatacggt aaggcgacgc tgacatggtt tgaagagatt ttcgaagagt attaactaat
    43561 ttcttcttac caattccacc atatcatacg gcagggtatt ggcagcttcc ttcaaggaat
    43621 agttctctaa gttatttaca ttttgtcgta atttcttggc atacttagtt gtaattaatc
    43681 gtttttcttc gtattcgaaa atcaacttgc gctccagata atagcctctc agcatttcat
    43741 tgatattgtt gggtttgaca cgattgataa cccgttcgac aaaggcacca ctgctgataa
    43801 tagttgtttc tcgaagacga gactcctgca taaaactaat caaagagcgt ctgtagactc
    43861 ccttcaggtt ttccaaactt tcaataatca tctccgtatt ggcaagatag agctctgcaa
    43921 tttggtcata atcaagagca cggagacggc tttgctcctt gttcttccag ctacggaagg
    43981 tctttccgag agtaaaaact tcatgaagga gaaaacgtaa aatccgcaaa gaaacaagga
    44041 aataataggt cagtcttgag gcaagtttac gattgattcc ttgttctata tttttcagat
    44101 aacgttggta aactcggtaa gcacgattgc taatgttccc ctcttcatag gcctgttcca
    44161 aaccatcact ttcaatacta agaatcaaga gtttcaaagc agcccaatct tcttgatcat
    44221 cctggttttc ttggcttaaa atgagatttt caatacgtcc atgataattg tcaatagccg
    44281 catagagggg aagtttattt ctggtgtctt ccaactcttt ttccaactct agcgttactt
    44341 cattcaaaat ggcgatatgc atgagataat ccttgctttc ttcctcttca tcagaaagat
    44401 gaggcaagac caagagacct gttaaaaagc tgacaagcgt cacacctgca acaaggaaaa
    44461 gcaagagagg atactcctgt tctagattac ttggtatcaa gagaatcgta gcaatcgaca
    44521 ccgttccctt aacacctgaa aaggtcaaga gaaacatgtc cttcatatac ttatttagct
    44581 ttttcttgag gcgtcgggtt ctataggcat aatagccata gatcataata aaacgaatga
    44641 caaagaggac aaaggtaagg acgatgagag atagcaataa aagtagagga ttatagattg
    44701 gattggtcaa gataggttct gctatcattt ccaactccat ccctaaaatc acaaagacag
    44761 aaccgttgag cataaaggtc actgtatgcc agaccgtctc ggtcaccgta tccacttggg
    44821 cttcgaggag cgtgattttc ttgaagcgac ttgcctttaa aattccagca actacgacgg
    44881 caataatccc tgaaacatgg acttcttctg ccagaaagaa ggtcactaga ggcaaactca
    44941 attctaataa aagttcactg gcaatatccg ttgcgcgcac acttagcaag aaggtatgga
    45001 ggaagcggtt ggtcatggct gttaaaaatc caattaaaaa accgcctagg attgaaaaga
    45061 tgagcgaact gctagcttgc cccagagaaa aagctccagt tgtccaagct gtcaaagcta
    45121 cctgaaaagc caccaaacca gaagcatcat tcaagagtcc ttcgccctta agaatattgg
    45181 acacgcgctt aggaaagcta aaacgctccg aaagagaggc aaaggccacc aagtccgtag
    45241 gaccaagggc tgccccaaca gccaagcaag ctgccaaggg aaggctgaac caaagaagat
    45301 gggccaagcc acccaaactc agggtcgaga taaaaatcac tggaaatatg agataaacaa
    45361 tgattcgcca gtgttttaaa atagccgtaa catctgcttc ttcagcctct cggaaaagca
    45421 agggtccgat aaccagtgcc aaaaacaact ccgtattaag gtgaaagtca gtattgggta
    45481 aaaagagacc aatcacaatt cccaaaagaa tctgcaccaa agggagaggc aaaaagggca
    45541 ggagcttatt ggttgtactt gagacaatca aaaccagtaa aaataggatg aggtaaatca
    45601 gtaattccac gcacgtcctc cttaatcttt tttacaacag gattcaaata tctccttctg
    45661 ctctttgatt ttttggtcaa tcttggaaca gtctttgtgc tcaatttttc tctggcaccg
    45721 ttccatttca agagcaacta attttttctt gattttaagc atttttttgc tcatatgtac
    45781 ttggtctagc acgcccaccg atcgttcgtg gtgggttgat tcaacaaaat tctggcgcat
    45841 ggcatccagc ttttcgtgta ggtattgttt atccatgtct gtatctctct aatttttcaa
    45901 tcatcactaa aaacggcggg ttgttgactt ggtttaaagt tcggtaaatg gcagctgtgt
    45961 actcttgtta gttcaactgg attacaaaat ccaagacagc atctctctcg aggtcgcctc
    46021 cttcatgacc atagtaaatc ataatagcaa ttcgtccacc tttgacaagt aagccacata
    46081 gctttcctaa tgcctcaatc gttgtctgcg gtcgggtgat gatagactta tcagctgacg
    46141 gcaaatagcc cagattaaaa atccctgcct tagcttttgt cacaaactgg tccagtgtct
    46201 catggccttg caagattaac tgggcatttg tcaagccagc ctgatgcaaa cgctcttggg
    46261 tcttttccaa ggcttgcttc tgaatatcaa aggcatagac ttgcttggct agcttggcta
    46321 aaaaaagcgt gtcatgacca tttcccatag tcgcatccac tacgacatcc tcttttgtca
    46381 cgacctcagc caaaaaatca tgtgccatct caagtggtct tttcattttc aaactcctgt
    46441 tttacagcct tgcatccttg aacacttcca cgacgtcgca tctccatctc aatgctgttg
    46501 agagcttccc atttattgag gctccacata agcccaatca gcatatccct aggtgcatct
    46561 cctgtgattc gatggatgac gatatgtttg ggaataattt ccagttggtc acagatgacc
    46621 ctgacatatt cgtcctgact catcaattgt aaacgtccct catggtaatc tcgttgcata
    46681 cgagtatttg tcataagatg gagcaaatgc agtttaatcc cttgaatatc gttatccgtg
    46741 acacaacggc ggacattttc aaccatcatc tcatgggttt caccaggcaa accattgatc
    46801 aaatgggaaa caatctcaat ttttggatac tttctcaaac gcttgaccgt ttccacctac
    46861 aattcataag aatgcgcacg gttaatcagg tcagaggttg cttcataagt agtttgcaag
    46921 cccaattcaa ccgtcacatg catgcactcc gataactcag ccaaatattc gatggtttcg
    46981 tctggtaaac agtctgggcg cgttccaata ttgattccta ccacacctgg ctcattgata
    47041 gcctgttcat aacgctctcg aataacttcc accttttcat gggtgttggt aaaattttga
    47101 aaataaacca gatacttctg aacatccggc cacttacggt gcataaagtc aatttcctta
    47161 taaaattgct cacggatagg cgcatctggg gctacaatag catctccaga acctgaaacc
    47221 gtacaaaaag tacagcctcc atgagccaca gttccatcac gattgggaca gtcaaatccc
    47281 gcatcaatag ggactttaaa agtcttttct ccaaagagtt ttcgataata atcattcaag
    47341 gtattataag gtattataag attttataac tttcattata acaaaaatca cccacaatct
    47401 caaaagcctg actttcctat aaattcctct gtttctcgtt tccattagcc tttttttatg
    47461 atacaatatg ggtatgattt taatgaaatt agcatctatt ttattattga tactgacctt
    47521 agtcatctgc attatcctaa ccaaactttt tagattaaaa aaactaggac gaaactttgc
    47581 ggatttggct tttccagtct tggtatttga gtattacttg attacagcta aaacctttac
    47641 ccataatttc ctccctagac tggggctagc cctctcgatc ctagccatta ttctcgtctt
    47701 tttcttcctt ttgaaaaaac gcagctttta ctatcctaaa ttcatcaaat tcttctggcg
    47761 tgcaggattc ttattaaccc ttatcatgta tatagaaatg attgttgaat tgttcttaat
    47821 gaaatagtcg aatccctaag cattttctag ggatttttgc tttctctaca aaatagtata
    47881 gacaataaca ctatacaatt ttatacaaag aaaagagtct gggacaatag tctcttatat
    47941 ccaaaaaggc aacggatttg ccgttgcttt tttgcatggt tacgatagtc ttggtaaaat
    48001 agaattgctt aataaaccat ttagaaaggc tatcccatgc atattcacta taacacaaat
    48061 caaacaactt taccactaga aatcagttcc ttcttaccac aagaccatct cgtctttact
    48121 attgaaaaag tggtgaatac cttggaggaa cgtcacttct acgccttcta tcatgccttt
    48181 ggtcgcccgt cttatcaccc taaaatgctt gtatctactc ttctatttgc ctattcacaa
    48241 gggattttct ctggtcgaaa aattgaaaaa tggaagagtt agtgacctta gattgtttgt
    48301 ttattgacgg aactaagatt gaagccaatg ccaacaagta tagttttgtg tggaagaaaa
    48361 cgacagagaa attctccgcc aaacttcaag aacaaataca agtctatttt caagaagaaa
    48421 tcactcccct cctgattaaa tatgccatgt ttgataagga acaaaagaga gggtataaac
    48481 agtcagctaa aaacttagcg aattggcact ataatgacaa ggaggatagc tacacacatc
    48541 ctgatggctg gtattatcgt tttcaccata ccaaacatca gaaaacacag acagactttc
    48601 aacaggaaat caaggtttac tacgctgatg aacctgaatc agcccctcaa aagggactgt
    48661 atatgaacga acgctatcaa aacttgaaag ctaaagaatg tcaggcgctt ttatctcccc
    48721 aagatagaca gattttcgct caacgcaaga ttgatgtgga acctgtcttt gggcagataa
    48781 aggcttgttt gggttacaag agatgtaatc tgagaggcaa gcgtcaagtg agaattgaca
    48841 tgggattggt acttatggcc aataacctcc taaaacatag tgaaatgaaa taagaacagg
    48901 acaaatcgat aaggacagtc aaatcgattt ctaacaatgt tttagaagta gaagtgtact
    48961 actctagttt caatctacta tacaataaga gaacgactca aaattaaaaa gctagagttc
    49021 cgcaattgga aatatctagc ttttttgtgg ttgagaacta ttttgttcca gactctttat
    49081 cttctattta ggacaagagt ttttctttgg tctttaatga taaagaaggt atcaaaattt
    49141 ctagtcttct tttttacctt tagtaactac taatcctgca ctcaaaccta gaagagctaa
    49201 acctgctgct actgctgctt ggcttgccgc actacctgta tttggtaact gggctttatt
    49261 agtttgacta gcttcacttg aatcaattgg ttttgtatct gctttttctg acacttgtgg
    49321 ttttttagct tcttgagcta ctggtttggt tccaaccaag acgatgcggt ctgtcggagc
    49381 ttctaccact tcacggagtt tttcttcctt acttccatca ggattaatcg ctgtaaagat
    49441 acgttcttta ccagtttttc cttcttgttc tacacgagtt tcacctagat acagtgttga
    49501 atcttttttc tcaactgtct tgtaggccaa atctttttca acaaattcga gttttggaag
    49561 atcttcttgt acagcagaaa ctggtttttc cttagtcaac tggatacggt attccttgac
    49621 ttgttttcca ctttctgaaa cgaggcgaac aagtactgga aggctatctt ctccactatc
    49681 taccacagtt gaagctactt gattgttttc ttcaactgag acttttggcc gttgaccttt
    49741 ataggtaatt tgatagtctt gacgattttc agcgaaatca gcaagttctt ttccatctac
    49801 aagaatcttc gattgcgtac tttcttgagg caattcactt ggtgcaagga aggtcatctc
    49861 aatcatcgca acaccgctct tatctgcttt acgctccata cgccatctca tagctttggc
    49921 tttgacagct ttaaatgtta cgttgatttc atcaccagct gcgatgtctt tatccgcacg
    49981 ataaggcaca gcttcccaat tttctggatt gttgaatgga tggtctgcgt cgtaggcttg
    50041 gtagtttgaa tagtaggttg gcacttcaaa ctctggaccg acatagcgtt ctaaaacgag
    50101 tttagttggt gcatccgtac cactatctgc aaagaagtga agtttggctt gagcaacagt
    50161 ccgttctaca atcttaccat tttcacggaa gatcacaccc gctgatactt ctggattaga
    50221 agatggtgtt ggtgaccagt ttgtccaacg acgattttct gaatgatctc cgtcattgag
    50281 atagtcaacg cggtcatgag agtttttgtc aatatcattt gttgctgaag caaaggcctg
    50341 gttactgttt tcatcatagt tagggttatc tgaaagagcc tcaccaagtt tgtctgtcac
    50401 tcgtacagtg acctcagcaa caaggtcact accaaggaca cggcctcgaa tagtaaattg
    50461 acctgctttt gtcagatttt ccgctggaac ttcttcccat tcaactgtca ggtcttttgt
    50521 ttcgtagccg tctttacctg tgaagtaaac tggaacctta gtcggcaatt caagtgcttg
    50581 acctacttgt agcaagcgag cttgtttaac cgcagcaact ggtttatgag aaagtaagtt
    50641 cttatcctta gtgaagtgca gacggtattc tcctaagatg tcgccatttt cagctttcgc
    50701 gatgacacga actggctcac cttcacgaac gcttggaacg acggtagcga gaccattgtt
    50761 gctaacactt gctgtgaccg ccgtaacttt tccatctaca gactcaaggt agtagtctgt
    50821 caaatcaggg ttgaagtttg ctaagtcttt gccgtcaact tggattcttg tttgtccttg
    50881 tttggctgcc gcaacttgtt tcgcaaagat ttgtacctct gtgatagacg ttccacgctt
    50941 gttatctgct ttaaccatgc gaatacgaac agcataggtt tcaactttat caaagctaaa
    51001 gtggttcatt tctccagcct tgagttgagc aggggctttt agattagtaa ctggtttcca
    51061 gttggcagaa tcattaaaga catggtcctc attaccaaca aaactagggt ttttaggagc
    51121 tgttgggaca gtcttaccaa cataatactc aatcacataa gacttcggtg caccaactcc
    51181 atggtcttcg tggaatccga cacttagatt atcaacggag cgtttgctca agatacctga
    51241 atctccaaac agaacaccga ctgaagcttc tggattacta cgattccagt ttgtccaacg
    51301 attggctggt tggttattgt aggaaatgag cttgtcatta acatttgaaa ctgggtcgct
    51361 tggatttgag tctgaagcaa aggcaagtgg caattctgaa ccggtccatt ggtcagaaat
    51421 gtttgcacct tgctcagttt gagcagatac gcgaacatga agtttagttg ttaattgagt
    51481 accttctaag cgaccattaa ctgtaaagac accttcctta gcgtattgct ctggacgaat
    51541 cgcatcccat gcaaccttag ctgatgaaac gtgaccattt gaatcatatg tccgaacact
    51601 ttctggtaat tgtggtgctt ctgcgattgg agttgtcaca ctgacttctt caactgaaac
    51661 gataccttct acagagactt ttgcacgcgc ttcaaggtca attccttcaa ctttacctag
    51721 tacttcaaat gtttgatagg agtctagttt ttctttcgga atagcttgcc aagtgacttt
    51781 atgagtttta gggaaacctt tgtcatactc aactgttact gttgctggaa gacttggttc
    51841 ctgatgcaaa tctgtcacta catttacagg acggatggat tgcgcaatct tcttctcagt
    51901 attggcttgg atagtgagtt caacttggcc tttagctccc tcatattcag cgttcagagt
    51961 gactgctcct ggcttatgca actcaagcat tcctttacga attgcgactt ccccttcacc
    52021 acttgtagag aaggttactt tatcagctgg taatacagct tgcgttccat cttgatagtg
    52081 agctcgaacc gacaatttga cagtttggtc ttctttgaga ctgtcagctt tttccacttg
    52141 caagctcaag tgagcaattt ttggcgcttc ttcaaggaat tgaattgcat aggtttgaag
    52201 agggccacca tctttaggct gaataaagat gctcgcacgc atgccgtttg ctgcgcttgc
    52261 ttgaagaact gtcacatcag cattttcagc acttgctgtg acttctggca attgggcacc
    52321 ataagataga gtacgatatt gcattggttg tcgactagta agacctgtta ctgcttcacc
    52381 tccaacagta acagttggca ctacaggtgc tgcaggattg ccttcttcta ccacaagggt
    52441 tgcatgaatt ggttgacctt ctaaataacc ggtcgcttga atacgagaac ctggaattgc
    52501 taacttaact ttatcttctt cggcaatctc ccagctatct acttcgtact cttgtacact
    52561 tccatcagtc aaaacatagg aaacagattt gtctacagaa ttcaagtcag tatttggagc
    52621 aatacgtttc acaactggta gctctgattt aagagcaatc acttctacac gagcttctac
    52681 ttctcgtccg tcagccatac ctttcaccgt tacaatacca ggcttgctca catctactga
    52741 agaccaggtt acaggacgtt ctgcacggct accatcactg tatacaaacg gaacagtggt
    52801 aggcatttca ggtgcctctc caataatggt ctgtactttt ggcacttctg tccccaaaac
    52861 agtcttctct tgtccttctt ttttaccagt aaagacagtg acttggttcg atttcaagag
    52921 atcagagtgg gcagtaaggg tgaatttccc tacttgttca gttgatttga caatggcaac
    52981 acctttacca ttaaatgctt tacgaatcca agaaccatct gcttgcgcct tatagcgttc
    53041 acggctggct tgttctccgt tatctacacc gaccagttga ccttggccat gcaattggaa
    53101 gcgaaccaga ttattagcag ttggaaccac attcccctgg ctgtcaacaa tttcatagta
    53161 gatgtaagtc aagtcttttc catctgctgc aatcgcatgg tcttccttaa taagacgaac
    53221 tgccgctggc ttaccagcag tcgtaatctt atctcgagca atttccttgc cagattcatc
    53281 acgagcaatt gcttccaagg tacctggttg ataggcaact ttccattcaa gataaagttc
    53341 attagcattt gcaccttctt ggtaagtccg cccatcgctg gtttgttttt tattgaaagt
    53401 cttaagacca agagattttc cattcaagaa caattctaca ctagaagcat tcgaataagc
    53461 acgaactgga atcttacctt ctgagtcagc tactttggat gctaattctt tgttttccca
    53521 gttccagtga ggaagaaggt gtaccatcgg tttcttctta acagaaaccc attggctttg
    53581 gtagagatag aagtcatgtt ttggaatgcc ggctgtatct acgataccaa agtaagagct
    53641 cttaacagga gtttgatttt ggttgtgcca tggtgtaggt tcaccaatat agtccgtacc
    53701 tgtccagata aactgtccag catagccagc gttgtcacgg tcaaaagtcc atgaagcggt
    53761 tgctgttttc ccccaaccca cacgatcatt cccatagtca gactgttcat aattacgctc
    53821 aggtccattg ctatgtttca attcacgttc agggcgatag taacttccac gtgtacgggt
    53881 tgctgatgat gtttctgaac cgtaaatcaa ccattttgga tgcttagctc taagggcttt
    53941 gtaattatct tcagaatagt taaatccaac agcatcgagt tcatcagcaa ttttctcatg
    54001 ccctccgcta ccattaccga aacggaattt atctgctccc atggtaacat agcgagtctt
    54061 atcaacatcc ttgataacct tgaccaaacg tttaacagtt gctaaagagt gggcatcacc
    54121 attagcttca cctatttcat taccaattga ccacatgaag atagcagggt tgtttttgcc
    54181 tctttcgacc atggtacgta ggtcaaaatc agaccatttt tcaccttttc gagcttctgg
    54241 gtgagtggca tctttttcaa agaaacgtcc atagtcataa ggtttcttgc caccatacca
    54301 cgtatcaaag gcctcttcct gaacaagtaa acctagttct gctgcgattt gcaaggtttg
    54361 ctcactagaa gggttgtggg ttgtacggat ggagttaact cccatctcct tcatttgttt
    54421 gagacggcga tattctgctt tatagttttc ttctgctcca agcgccccat ggtcgtggtg
    54481 caaggatact ccatggaatt taatacgttc accattcaaa gagaaacctt catttggagt
    54541 ccagtgatag taacggtaac caaacaaatc cttcttagca tcaaccaatt gaccgtcacg
    54601 gtaaacacgc gtaatcaatt cgtacaaggc aggtttgtca tttaaaacgg tccagagttt
    54661 tggtctttca acttctaaaa tcgcatctag gcttgttgat tcatgtgctt ttaaggtacg
    54721 actcgctgta cgaactaagc ctgttacagc atgaccacct cgttcaacga tttgatattc
    54781 ggctacaagt tcatggtctt tgtcgtccgt attgacgatt ttgctggtca catgagtttc
    54841 aaccttgcca tgttgttgtt cttcaagttt tggtgttaaa atagttgtcc catttttctc
    54901 aacatgcacc ttatctgtca cttgtaaagt cacatcacga tagataccac ttcctgaata
    54961 ccaacggcta cttggctgtt tgttgactgc atggacagca atcacattct cacgaccatc
    55021 tttgtgaagg tatttggtga tatcgtatga gaactggtta taaccatttg gataatgccc
    55081 cactaactga ccattgacat aaacttgaga atccatgtag acgccatcaa aagtaaggcg
    55141 aacatttttc ttgaggtctt tttcatctag tttgaaaatc ttgcgatacc aagcttcccc
    55201 accgttgagc tgtccacctt cattttgtgc aggagattca tgatcgaaat cgttaaagat
    55261 actccagtca tacggtaaat ctaatttttt ccacgtagat acgtctgcat caggtttaat
    55321 ggcttcctta gaatttgcat tgagtttaaa ataccaattt tgattaaaat ccactttcct
    55381 gtcttcaatc atttgattca cttcttcatt tgttacagct ttagcatctt ccttgagcgg
    55441 tttttcttga tttgaagctt gtgattctat ccttggagct ttttcttccg gtttagcaga
    55501 cactttttcc tcttttggag ttacggcttc atcttctttc ttctcagatg caatagcctc
    55561 agttgaacta ggttcacttt gttctgtcct ttcaactaca tttttagttt ccaaagcttt
    55621 atcagccttt tcttctacta tcattttttc ctctttaggt ttctcagcag tatgagtaat
    55681 aagtgtttca tccgcataaa ctacagattc tccagctata tttcctccta atagaactgc
    55741 acaagtccca atcattactg agcaagctcc cacagcaaac ttacgaatgc tataaactct
    55801 tttccgattc caatggcctt tccccataaa accctcctta tattatattt agtgcagtta
    55861 gctactacca aagcccaagt ggtatacatg gtatgacaac ctagtttcaa caatttacac
    55921 tctgcgaaaa tccaattcaa acttcgtcag tgtcgccttg ccgtagatat gattactgac
    55981 ttcgtcagtt tcatctacaa cctcaaaact gtgttttgag caacctgcgg ctagcttcct
    56041 agtttgctct ttgattttca ttgagtttat attttatagg agcgcattat tttgcttttg
    56101 ctgcgtactc ttcgttacgt ttgatcattt gttttctgta ccaagcaaag ataccgatat
    56161 agaatacaag gaaggctact gcaccaagga ttgctttgat atcaccagtt gtagtgttac
    56221 caattgtcca accaagaagt ttttcgattg gtccttcaag agtagagtga gtaatcaatt
    56281 gagtttggct cacaccttct gggaaggcac ctacaccttt agcaagttct gttgcaaatg
    56341 gtgcaataag ggtacctgaa agaaggaaga gtggcaacaa gagtgttccg aagataatca
    56401 tacggagcaa tttaccacga gttacaacca agagagctgg agtaacaccc atagcgatga
    56461 tacctgcaag tggcaagata ccatttccaa cttttgaaag aagcactgct tcaatcaaca
    56521 tgattggtgc aagtacgttg gcacaagccc agatttcagc acgaccagcg atgaatggcc
    56581 agtcaagacc gatattgaat ttacgtcctt gaagacgttt agtagcaacg tttgtaatac
    56641 cttgtgatag tggttctacg gctgcgatga accatgaacc gataagtgag aagagttcca
    56701 aagatacacc ggcagtcaaa ccaagagaca accatccttt gataacaaga cgccatttat
    56761 ctgcatctgc aacacctgca attggatgtg gagttcccat aataccgata acgataccaa
    56821 ggatgaaacc gatgaagaat ttagatcccc agaaaccgat tttcttgttc aatttagcag
    56881 catcaaagtc atatttatca aggcctggga agaatttttc aaaaatctta tccaaaacca
    56941 tgataactgg gttcatcatg tagttcatgt gagttgatgt cattggtgat gaacttgggg
    57001 cgttaagaag gtcatcaaat gtaggtttca tcaagtcaga gttgataatt ttcaacacac
    57061 cgacaaggac gatagctgct gtagcaataa agagtgaaac cccttgactc acaccattgt
    57121 tatcagcata ccatttaatc aagagacctg tgatagacaa gtgccagata tcaaagatat
    57181 cgacatcaag tgtatcggtt ttcttcatag caagcatcac tacgttgaca atcaacatga
    57241 tgagcaagaa gtatagtgtc caagcagaac cccaagtgat tgttgcgagt ggtgcccaac
    57301 caacgtctgt aatactcaat tggataccag tgttttcaac gaattttgca agtgatgctg
    57361 agaaagcacc atttagcata ccgatgatag caccgatacc tgtaagagcg atggcaagtt
    57421 tgataccacc ttcaagcgct ttggagaatt tcactccaaa aagtaaagcc aatactgtca
    57481 aaatgattaa catgatgaca ggtccaccca tttctaagat gggattgaaa acctttccga
    57541 ttaggtcaaa gattgcatcc ataacagttc ctcccttttt tatgttatat gaatgttaac
    57601 aaattagaat tagcttaatc cgtgttcttt aatagctgct tcaatattgt caaatactgg
    57661 agcgctcatt gctgggatac ggaataagat tgg
//
LOCUS       DAVHSL010000007        54921 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000007 DAVHSL010000000
VERSION     DAVHSL010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.007"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(145..2034)
                     /locus_tag="VVR39_000422"
     CDS             complement(145..2034)
                     /locus_tag="VVR39_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU6029966.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEDDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2172..3737
                     /locus_tag="VVR39_000423"
     CDS             2172..3737
                     /locus_tag="VVR39_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6029967.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3737..4477
                     /locus_tag="VVR39_000424"
     CDS             3737..4477
                     /locus_tag="VVR39_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6029968.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4586..4801)
                     /locus_tag="VVR39_000425"
     CDS             complement(4586..4801)
                     /locus_tag="VVR39_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029969.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5672..6922)
                     /gene="ilvA"
                     /locus_tag="VVR39_000426"
     CDS             complement(5672..6922)
                     /gene="ilvA"
                     /locus_tag="VVR39_000426"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU6029970.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLN
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6972..7328)
                     /locus_tag="VVR39_000427"
     CDS             complement(6972..7328)
                     /locus_tag="VVR39_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6029971.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7566..7802)
                     /locus_tag="VVR39_000428"
     CDS             complement(7566..7802)
                     /locus_tag="VVR39_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6029972.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7909..8931)
                     /gene="ilvC"
                     /locus_tag="VVR39_000429"
     CDS             complement(7909..8931)
                     /gene="ilvC"
                     /locus_tag="VVR39_000429"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6029973.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLTDVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(8997..9473)
                     /gene="ilvN"
                     /locus_tag="VVR39_000430"
     CDS             complement(8997..9473)
                     /gene="ilvN"
                     /locus_tag="VVR39_000430"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU6029974.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9466..11166)
                     /locus_tag="VVR39_000431"
     CDS             complement(9466..11166)
                     /locus_tag="VVR39_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU6029975.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11367..13034)
                     /locus_tag="VVR39_000432"
     CDS             complement(11367..13034)
                     /locus_tag="VVR39_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU6029976.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13037..13402)
                     /locus_tag="VVR39_000433"
     CDS             complement(13037..13402)
                     /locus_tag="VVR39_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6029977.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13559..13747)
                     /locus_tag="VVR39_000434"
     CDS             complement(13559..13747)
                     /locus_tag="VVR39_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU6029978.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13863..14039)
                     /locus_tag="VVR39_000435"
     CDS             complement(13863..14039)
                     /locus_tag="VVR39_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU6029979.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(14150..14348)
                     /locus_tag="VVR39_000436"
                     /pseudo
     CDS             complement(14150..14348)
                     /locus_tag="VVR39_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(14603..16147)
                     /locus_tag="VVR39_000437"
     CDS             complement(14603..16147)
                     /locus_tag="VVR39_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU6029980.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVSGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16360..16662
                     /gene="gatC"
                     /locus_tag="VVR39_000438"
     CDS             16360..16662
                     /gene="gatC"
                     /locus_tag="VVR39_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU6029981.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16662..18128
                     /gene="gatA"
                     /locus_tag="VVR39_000439"
     CDS             16662..18128
                     /gene="gatA"
                     /locus_tag="VVR39_000439"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU6029982.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18128..19570
                     /gene="gatB"
                     /locus_tag="VVR39_000440"
     CDS             18128..19570
                     /gene="gatB"
                     /locus_tag="VVR39_000440"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU6029983.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19699..20259
                     /gene="efp"
                     /locus_tag="VVR39_000441"
     CDS             19699..20259
                     /gene="efp"
                     /locus_tag="VVR39_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU6029984.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20281..20670
                     /locus_tag="VVR39_000442"
     CDS             20281..20670
                     /locus_tag="VVR39_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6029985.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20663..21085
                     /gene="nusB"
                     /locus_tag="VVR39_000443"
     CDS             20663..21085
                     /gene="nusB"
                     /locus_tag="VVR39_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU6029986.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21134..21511)
                     /locus_tag="VVR39_000444"
     CDS             complement(21134..21511)
                     /locus_tag="VVR39_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6029987.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYLMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21874..22059)
                     /gene="briC"
                     /locus_tag="VVR39_000445"
     CDS             complement(21874..22059)
                     /gene="briC"
                     /locus_tag="VVR39_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU6029988.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22218..22985)
                     /locus_tag="VVR39_000446"
     CDS             complement(22218..22985)
                     /locus_tag="VVR39_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU6029989.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(22982..23848)
                     /locus_tag="VVR39_000447"
     CDS             complement(22982..23848)
                     /locus_tag="VVR39_000447"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU6029990.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(23885..25252)
                     /gene="accC"
                     /locus_tag="VVR39_000448"
     CDS             complement(23885..25252)
                     /gene="accC"
                     /locus_tag="VVR39_000448"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU6029991.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25264..25686)
                     /gene="fabZ"
                     /locus_tag="VVR39_000449"
     CDS             complement(25264..25686)
                     /gene="fabZ"
                     /locus_tag="VVR39_000449"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU6029992.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(25683..26168)
                     /locus_tag="VVR39_000450"
     CDS             complement(25683..26168)
                     /locus_tag="VVR39_000450"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU6029993.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26171..27406)
                     /gene="fabF"
                     /locus_tag="VVR39_000451"
     CDS             complement(26171..27406)
                     /gene="fabF"
                     /locus_tag="VVR39_000451"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU6029994.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGEIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27428..28159)
                     /gene="fabG"
                     /locus_tag="VVR39_000452"
     CDS             complement(27428..28159)
                     /gene="fabG"
                     /locus_tag="VVR39_000452"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU6029995.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28193..29113)
                     /gene="fabD"
                     /locus_tag="VVR39_000453"
     CDS             complement(28193..29113)
                     /gene="fabD"
                     /locus_tag="VVR39_000453"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU6029996.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29106..30080)
                     /gene="fabK"
                     /locus_tag="VVR39_000454"
     CDS             complement(29106..30080)
                     /gene="fabK"
                     /locus_tag="VVR39_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU6029997.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30199..30423)
                     /locus_tag="VVR39_000455"
     CDS             complement(30199..30423)
                     /locus_tag="VVR39_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6029998.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30483..31457)
                     /locus_tag="VVR39_000456"
     CDS             complement(30483..31457)
                     /locus_tag="VVR39_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU6029999.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31457..31891)
                     /locus_tag="VVR39_000457"
     CDS             complement(31457..31891)
                     /locus_tag="VVR39_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6030000.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(31985..32770)
                     /locus_tag="VVR39_000458"
     CDS             complement(31985..32770)
                     /locus_tag="VVR39_000458"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU6030001.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33139..34503
                     /locus_tag="VVR39_000459"
     CDS             33139..34503
                     /locus_tag="VVR39_000459"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU6030002.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKKEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34506..34877
                     /locus_tag="VVR39_000460"
     CDS             34506..34877
                     /locus_tag="VVR39_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU6030003.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35091..36365
                     /gene="serS"
                     /locus_tag="VVR39_000461"
     CDS             35091..36365
                     /gene="serS"
                     /locus_tag="VVR39_000461"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU6030004.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36390..37289)
                     /locus_tag="VVR39_000462"
     CDS             complement(36390..37289)
                     /locus_tag="VVR39_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU6030005.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKYPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TVICLTILFFVLGAYLIWLRKKV"
     gene            complement(37398..37946)
                     /locus_tag="VVR39_000463"
     CDS             complement(37398..37946)
                     /locus_tag="VVR39_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU6030006.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38164..39486)
                     /locus_tag="VVR39_000464"
     CDS             complement(38164..39486)
                     /locus_tag="VVR39_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU6030007.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39577..39665)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39829..42165)
                     /locus_tag="VVR39_000465"
     CDS             complement(39829..42165)
                     /locus_tag="VVR39_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU6030008.1"
                     /translation="MNKKILETLEFDKIKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42269..42817)
                     /locus_tag="VVR39_000466"
     CDS             complement(42269..42817)
                     /locus_tag="VVR39_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU6030009.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42814..43116)
                     /gene="zapA"
                     /locus_tag="VVR39_000467"
     CDS             complement(42814..43116)
                     /gene="zapA"
                     /locus_tag="VVR39_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU6030010.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43203..44084
                     /locus_tag="VVR39_000468"
     CDS             43203..44084
                     /locus_tag="VVR39_000468"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU6030011.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVATFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQITPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44088..44702
                     /gene="lepB"
                     /locus_tag="VVR39_000469"
     CDS             44088..44702
                     /gene="lepB"
                     /locus_tag="VVR39_000469"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU6030012.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            44830..47196
                     /locus_tag="VVR39_000470"
     CDS             44830..47196
                     /locus_tag="VVR39_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU6030013.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEVPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47244..48527)
                     /locus_tag="VVR39_000471"
     CDS             complement(47244..48527)
                     /locus_tag="VVR39_000471"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU6030014.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49335..50471)
                     /locus_tag="VVR39_000472"
     CDS             complement(49335..50471)
                     /locus_tag="VVR39_000472"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU6030015.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQRTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIDQIVEYI"
     gene            complement(50533..50970)
                     /locus_tag="VVR39_000473"
     CDS             complement(50533..50970)
                     /locus_tag="VVR39_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030016.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISVFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(50972..52927)
                     /locus_tag="VVR39_000474"
     CDS             complement(50972..52927)
                     /locus_tag="VVR39_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6030017.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYIKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(52951..54720)
                     /locus_tag="VVR39_000475"
     CDS             complement(52951..54720)
                     /locus_tag="VVR39_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU6030018.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGVFIACGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGSIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSADLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDESVASLTGASPIAEIEGDIPTSAPVDSQQIDLNPIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        16273 a        12442 c        10200 g        16006 t
ORIGIN      
        1 ggctttttgc cgtgctctaa aatcatcgcc aaatcatcaa attgaaataa gaaatagttt
       61 agataaaact attgactttt cttatagttt gtctttcttc tatcttccat tatatcatac
      121 tttttcagtc tatggtagct ctctttaaaa ggctccgata ctgccgccac ctccgcctcc
      181 agagaagcca ccgccagaac ttccacttcc agaagatacg gagtaggtac ttgctgtatt
      241 tgcgacacta gcataatggc tcatttgcgc gcttgaatga taaaacatac tgtgccagcc
      301 ataagctaca tatagattga tatctggatt ttcaacttga atctgatgaa ccttcatcaa
      361 atgactaacc ttgtccgcat agccaaataa ggttgcatag accaagagac gattccaaac
      421 aacaatactt tccaattcag ccttatccag tcgtgcaatc tcacgcaaca tattttcaaa
      481 actggtccag agatagtaga cctcagctcc cgcttcattt agaacaccat cacgattatc
      541 tagtcgaagc ttccaataat agaaaacaga caaaactaac cctagaaaac caagtattgg
      601 caaagggagg taaagatagc catgaacgtc taaactgtac aagaacaaac caaatccgat
      661 aaataggggc aagatagtca agacacccat acccacttgc aaagcctttt ccaaaccagt
      721 taaaggacga tagtaatctg ggagccccca gaaggaaact cgttttctca ctccttcttg
      781 catctggttc aatacctctt caaaagaaga tttgagttga agccctcttg cttgaatccg
      841 tttttcatca gaaactttgg ctctacgata aagactatca gataccttgt aatccgcaaa
      901 caaattggaa agagtttctt cttttttacc tgaaaaagct agatttaggc agtctttctc
      961 aaagcttgac aaaccatctt cttttactag cctcaaacca actgcatctc cttctgaaat
     1021 gatagagaca ttcccacggt ctatcacatc tagcaaggta gcttgaataa gttgatcaaa
     1081 ggtgaatttt ccagctccct tgaccaaggg actcacttcc tccaaggagg tcgagtagac
     1141 tgcttctgat aaaaccatag gctctaattc cattgggggt tcatagagac gatgattttt
     1201 agcatatttg attgaaggag cggtctttct tctatagata aaatagaaac agatgctcaa
     1261 taacaaggag atggaaagga tcgaagggaa gatccaagta agtagttgtt tactttgctc
     1321 tttttcttta acgatcgaat cctctatctt attaaactct tctaaacgat tccctttcaa
     1381 gccctgatcc ctagcgctag caaaatcagt tcgcggccag taggcatgca attcaactcc
     1441 acgcttagcc ggaagattgt ctaaacgaat agtataatca aggttactct tttcaaccgt
     1501 tctctctcta aaaagtttcc ctgtatggaa aaagagtttc tcagccccct tgtctcccct
     1561 tacatgaaat tcaaactttt caatagactc tgaactatct gtcagaggtt gccaatttaa
     1621 ttcagcgata tcatcataaa ggaaaagtaa attttttaag ttccagacga ggtcaacttc
     1681 aactatgtcg tcctcctgac ctggattata gactctcaca gtataaccat ccgcttcttc
     1741 tgttacttcg ctagtcacat ctgctagttc tgcaccgttt ttcgcggcct gaacctttgg
     1801 atgagggtca atgtcaaacc cgctaggcat cttaccagca cgtccaagtc ccacgatttg
     1861 gcccttaaag tcctcctcaa actggtaaac tatcttctgt ctaaactctg ccgtattatc
     1921 tgcatgaata tacaaatccc cttgataaga gtttatcttg aaatcaatgg caaaaacaga
     1981 gagtggaaga aggcaaaaca agcctaacac cagtaagaaa aaagtttttt tcatcaacta
     2041 agcccccttt ttatctttct tatcattata gcattttttc gtaagtaaag gcttacttat
     2101 gttgaaaaat tacgcatttt tcgataaaat aggagacagt tattttttaa tagatcagaa
     2161 taggagaaat catgagaaaa atatacttat ctattttcac aagtctcttg ctgatgctag
     2221 gacttgtcaa tgttgctcaa gccgatgaat atttacgcat cgggatggaa gcagcatatg
     2281 ctccctttaa ctggacccag gatgatgata gcaacggagc tgtcaaaatc gatgggacca
     2341 atcagtatgc caacggatac gatgttcaaa tcgccaagaa aatcgctaag gacttaggta
     2401 aagaaccttt ggttgttaaa accaagtggg aaggtctagt ccctgccctt acttctggta
     2461 agattgacat gattatcgca ggtatgagtc caactgcaga acgcaaacaa gaaattgcct
     2521 tttcgagcag ttactacact agcgaaccag ttctactggt caaaaaagat tctgcctatg
     2581 caagtgctaa atctttggat gactttaatg gtgcgaaaat cacttctcaa caaggtgtct
     2641 acctttatga cttgattgca caaatcacag gtgctaaaaa agaaacagcc atgggagact
     2701 tcgctcaaat gcgccaagct cttgaggctg gtgtcatcga cgcctatgtt tctgaacgcc
     2761 cagaagctct gactgccgaa gccgctaact ctaagttcaa gatggtccaa gtagaaccag
     2821 gtttcaaaac tggggaagaa gatacagcta tcgctatcgg gcttcgtaaa aatgacaatc
     2881 gtattagcca aatcaatgcc agcattgaaa ccatttcaaa agatgaccaa gttgccttga
     2941 tggatcgtat gatcaaggaa caacctgccg aagctacaac aactgaagag actagcagta
     3001 gtttctttag ccaagtcgct aaaattcttt ctgaaaactg gcaacaactc ttgcgtggtg
     3061 ctggtatcac tcttttaatc tctatcgtcg gaaccatcat aggtctcatt attggacttg
     3121 ccattggtgt cttccgtact gctcctctct ctgaaaacaa agccatttat ggccttcaaa
     3181 aactagtcgg ctgggttctc aatgtctaca ttgaaatttt ccgtggtacg ccaatgattg
     3241 ttcaatcgat ggttatctac tatggaactg cccaagcttt cgggatcaac cttgaccgta
     3301 cactggctgc tatcttcatc gtttcaatca ataccggtgc ctacatgact gaaatcgtcc
     3361 gtggtggtat cctagcagtt gacaagggac aatttgaagc tgcgactgct cttggtatga
     3421 cccataacca gaccatgcgt aagattgtcc tacctcaggt agtccgtaac atcctacctg
     3481 caactggtaa tgaatttgtc atcaatatca aagatacatc tgtattgaac gttatctctg
     3541 ttgtcgaact ttatttctca ggaaataccg tggcaacaca aacctatcaa tacttccaga
     3601 catttacaat catcgccgtg atttactttg tcctcacctt caccgtaaca cgtatcctac
     3661 gctttatcga gcgcagaatg gacatggata cctacactac aggtgctaac caaatgcaaa
     3721 cggaggattt gaaataatga cacaagcaat ccttgaaatt aaacacctca aaaaatccta
     3781 tggacaaaac gaagtgctaa aagacatttc tctcactgtc cacaagggag aagttatttc
     3841 tatcatcgga agctctggaa gtgggaaatc aaccttccta cgctccatta acctacttga
     3901 aacgccaact gatggacaaa tcctttatca tggacaaaac gtcctcgaaa aaggctatga
     3961 cctcacgcaa taccgtgaaa agttagggat ggttttccaa tcctttaacc tctttgaaaa
     4021 tctcaacgtt cttgaaaaca caatcgtcgc tcagacaact gtcctaaaac gcgaacgcac
     4081 agaagctgaa aagattgcca aagaaaacct ggaaaaggtc ggcatgggag aacgctactg
     4141 gcaagccaaa ccaaaacaac tctcaggtgg tcaaaaacaa cgtgtggcca tcgctcgtgc
     4201 cctctccatg aatccggacg ctattctctt tgatgaacca acatcagctc tcgatccaga
     4261 aatggttgga gaagtcctca aaatcatgca ggacctggct caggaaggct tgaccatgat
     4321 tgtcgtaacc catgaaatgg aatttgcccg tgatgtctct caccgtgtta tctttatgga
     4381 taagggcgtg atcgctgaag aaggtaaacc agaagacctc ttcaccaatc ctaaagaaga
     4441 ccgaacaaaa gagttccttc aacgctatct caaataaaaa gaaaaggctg catcaaccgt
     4501 gcagtctttt tgctgtcctc aaaatgaaaa ggcagattct ctatctctac tacttgaagg
     4561 tcaagaatcc gccgttatcc aaagattaat cttcaaattt ttcataattt ttttcataga
     4621 aatcaattag gcctagggct gtttcaaatg aaatattttt tacttttgca cgaccctgcg
     4681 ccagagcaat gatagacatt tcacgcgcat tcgtttcttt agagatacgg tagcctgtga
     4741 ttttcttatc acgaacccag ccaacaactg attctacttt ttcaaagttt gacttagcca
     4801 tgtttttctc ctattttctt ctttataata tttaattgta tacgttttta ctacttttgt
     4861 caataaaaaa aaacatatat tcaacgagaa taattagttc agaattttct tacttccttt
     4921 ttaaatccga taatatatag gttttgctag cctctacacc ataaatattt gctaataaaa
     4981 atactgtatt attaccctct taaggtgcga aattattcaa gttcttaaaa atgcttctct
     5041 atttccgtaa gatagcttat ttcttcgatt taagaactga agatgatagt tctaaccttt
     5101 agaaatccaa gccttcacta gctcaaaaac tcctatcttt cttcctcaat aaatcatctg
     5161 agagataggt attccttata tccttcaaat tcatcactcc tttggatatt gaggtgctag
     5221 cctagaagca gacacccgat tatctaaacc atccttaata aagatgacaa gacagataag
     5281 ctcagttaat tacttatata tccttttaat atggtatatt tgtcaacaaa aagaaatcaa
     5341 atcatacctt atactcaatg aaaatcaaag agcaaactag gaagctagtc gcaagttgct
     5401 caaaacactg ttttgaggtt gcagatagag ctaacgtggt ttgaagagat tttcgaagag
     5461 tattaaagac agtgtgacta tgcttgtcaa tagataggaa atcaaaatga aggatggaaa
     5521 tctgagccaa acatcataag tgctataatg aacagaagta agaattgcac gataagtttt
     5581 ctaaaaccat aggaatcgtc ccctttcttc atcttcatta tagcacatat acatcagttg
     5641 tacaaataat atgatatttt tttattagtc ctcagacaag catattataa agcgtttcat
     5701 taccatttaa gttaatataa gctggatcaa aaccttccat tctacggttc aaacctgcat
     5761 aatcatgctt atctgccaaa gcgatcccaa tcaatactgg gcctgttccc ttgctagctc
     5821 gtttgatata ctcaaaacgt gtgatatcat catttggccc caggatatca tttacaaact
     5881 cacgcaaagc tcctggacgc tgtgggaaat tgaccacaaa gtaatgtttg ataccatcat
     5941 aaatcaaggc acgctcttcc atttctggca tacggttgat atcattattt cctccagaaa
     6001 tgatacaaca aatggttttc cccttaatat attcagctaa aacctctaaa gaggcgatac
     6061 tagccgctcc agcaggctct gcgactatcc cttgcttaga gtaaaggtca atcaaggttt
     6121 cagaaatcaa tccctcatcg acacctacca aagtttgaat atgttgacga gttgcttcat
     6181 aggtcaactg acctaccttt tgcacagcaa tcccatccgc aaatttatca atttccttga
     6241 gtttgactgg acctccagcc tcaaaggcag ctttcatgga acgcgctcca ttcgcctcta
     6301 ctccgataac ctcaatctct ggacttgttt ccttgatata ggtagaaacc ccggcaatga
     6361 gaccgccacc accaacagga accaagacag catcaaaatc aatcgattct tttcgagctt
     6421 cttctaaaat ctcataagca actgttcctt gacctgcttg aacatgagca tcatcaaaag
     6481 gatcaataaa ggtacgattt tcagagactg taaattcttg agctgctttg gctgaggcat
     6541 caaaggtatc tccaactagt ttaatagtta caaaatcccc accaaaaaag cgaacctgac
     6601 caatcttttg ttgtggcgta gtaataggca taaagatagt agcaggaatt ttcatttcat
     6661 tacaagtata ggctactccc tgcgcatgat ttcccgcaga agcgcagact accccacgtt
     6721 cacgttcttc cttgctgagc tgggaaatgg cataataggc accacgaatt ttaaaggagc
     6781 gaacacgctg ggcattttct tttttcaaat aaatcttagc accatacttc tccgataaat
     6841 aatgatcgta atccagtgga gtattcacaa ccacaccgtt caagaccttg tgagccttga
     6901 ttatatcttt tgaacttaac atataaaacc tctttttcta taaaaaacag tcactaatga
     6961 ctgtttttta gttattcatc tccgaaaact tcagtaacac tttcatggta tttatgagcc
     7021 atacgaatcg aaaactcttt aggaagttca taacgatttg tggaaatcca atcatataac
     7081 cattctacca aactttcttc actatcatta cgatggaaga taaaatagtt taaaatttct
     7141 ttatattcta catcattcaa atccaacgtg tctacaaatt gactacgagg aacaaaatta
     7201 gaatctaatt ttcttagttg atctgtcaat tctcccaatt gtaaatccaa ctgaaaaaat
     7261 agtttttgca gttgcctatc agtttcatca catcctgtct tgatagaaaa caaattggta
     7321 atattcatat gatttcaacc cctaaataag tacatctaat atcccacgaa tagctgaagc
     7381 taaagttttc gcagtccagt catttaaacc cgattctttc aatccagatg caataatttg
     7441 ctctatttga tataaaccgc catctatcgt ctcatttatt ctgcgaagag gaccttcaat
     7501 ataggataaa gcttctccga atctaacagc tgatttaggt cctaatgatt taccaactat
     7561 atttgttaat gttttttatt tctcaaaatc catttcgcta tataacgagc agatttagtc
     7621 gcaccagctc tctcaaacgg agaatgaatt tcaagacctt cttctctagc tatttgtgcc
     7681 aatttgaaga attgttcaaa ggtcatatgc aacctaccat cttcaaaatt agcatcatca
     7741 taaatgttaa ttacagcatt ttcatcatac gaccaatctg ctttattttg gtctgctagc
     7801 actattaccg acggtgtaat tacattatac aactagaacc aataataacg atgcaatttt
     7861 tctcataatc tttttcataa aatcatctcc agcgctatat atttctaatt agttatagat
     7921 tttgaatgca tcatcgtcgt ttttaccaac gaatggcatt gctttacgca attctgcacc
     7981 aactttttca atttcaaggt tagctgcttg ttcacggtaa gcagtcaatt ttggacgtcc
     8041 agctttatag tcatttacaa agtcatttgc aaatttacca ttttggatgt ctgccaagac
     8101 agccttcata ttttctttaa cttgttcagt gattacacgt ggacctgata catagtcacc
     8161 gtattcagca gtgtttgaaa tagattgacg cattttcttg aatccacctt catagatcaa
     8221 gtcaacgatc aatttcattt cgtgaagaac ttcaaagtaa gccaattctg gagcgtaacc
     8281 tgcttctgtc aagacttcga aacctgcttc gataagggca gtcaaaccac cacaaagtac
     8341 agcttgttca ccaaacaaat cttcttcagt ttcttctttg taagttgttt caagaagacc
     8401 tacacgagcc gctccaacac ctttacacca gtccatagca atgtttttag catttcctgt
     8461 tgcatcttgg tatactgcat aaagagctgg aacaccaaat ccttcttcgt aagtacgacg
     8521 taccaagtgt cctggtcctt taggagcaca catgaagaca tctacatccg caggaacttt
     8581 gataaattca aagtggatgt tgaaaccatg ggcaaatcca actgcgtttc cagcttccaa
     8641 gtttggagcg atttctgctt cgtacaattc ttgttgaatt tcgtctggcg ccaagatcat
     8701 gataacatca gtcaacttag tagcttctgc tactgtgtaa gtatcaaatc catcttcttt
     8761 tgctttatca aaagatttac ctggacgtac acctataata acgtcacgac ctgaatcacg
     8821 caagttttga gcatgcgcat gcccttgtga accataaccg ataacggcga tttttttacc
     8881 gtcaagtgct gctactttaa catctttttc atattccatt tgaactgtca tagcttttct
     8941 ctcttttcta ttatttattg ccttttaggc tggtttaata aatttaagtt ggatttttaa
     9001 tcgcgggtaa atccagttgc acccgttcga gcaatattgc gaataccgta tgggcgaatg
     9061 actctcaata gggcttcgct cttttctgca tttcccgtca tctgaatggt aatcgagctt
     9121 ggcgctacgt ctaccactgt tgcacggaaa ggttgaataa tcgctaaaat ctcagctctc
     9181 ttctcagctg gcgctgacat cttaaccaaa atcacctcgc gctccaaatg aggcttgtct
     9241 gtaatatctc gaatgcgaat cacatcaatc tgacgattga gttgtttgat gatttgctcc
     9301 acttcatcat gagaagcaac atcaataata atagtgatac gcgatacatt cggatcttct
     9361 gttgctccaa cagagatgct ttcaatatta acctgacgac gagataggac acctgtaaag
     9421 cgattgagga ctcctgaacg attttgtagt tttgctgtta acattctacg catggaactg
     9481 cacccccaac atctcatgat tactcttacc agccggtacc attggtaaca cctgttcctt
     9541 acgagaaata tctacctcaa ttagcatagg aacatcctca gtgatgactt caaggtcttg
     9601 agccaaggtc tcaggattgt caaacttata gtttttaata ccataagcct gcgccatcaa
     9661 ttggaaatca ggaagggtat caaagaccga ctctgatgtt ctgccttcat agaaggattc
     9721 ctgccactgg cgaaccattc cgagtgaatg attgttcagc ataaccacct tgattggcac
     9781 cttgtaaata ttcaaaatag ccaactcctg gttagtcatt tggaaaccac catccccaac
     9841 aaacaagact acttccttat ctgggttagc aattttagca ccgattgctg ctggaattcc
     9901 aaagcccatt gttcccaaac cacctgaagt cactaactga cgttcatttt ggtagggata
     9961 atactgagct gtccacattt ggtgttgacc aacgtctgtt accacaatgg catctccatt
    10021 cgtcaattca ccaattcgtt caataactgc ttgcggttga accacacgct ctttcttgtc
    10081 ataagaacga acacgattct tgtctttagt gactttctca atccactttt cagtattgtt
    10141 gtgaactgtt ggttctgcta gcaacatttg caaggccttc ttagcatctc caactacagg
    10201 aatgtctgca ctgataatct tgccaatctc agctgggtca atatcaatgt gggcaacctt
    10261 agcattctta gcgaaagtct taggattccc cgtcaaacgg tcatcgaaac gagaaccaat
    10321 actaatcata aagtccgctt ccgtcatggc aatatttgct gcgaatgacc cgtgcatgcc
    10381 tcccattcca agaaagagtg ggtgactcgt tgcaattgtt ccttgtccca aaagactggt
    10441 taccactgga atttgatagc gttctgcaaa ttcatttagt tccgtagcag cctcagcata
    10501 actaattcca ccaccagcta acaagactgg ctttttagcc ttggacaatt gcttcaagat
    10561 tttcttgatt tgcatatcat tcggctcaag agtcggctga taacttggta aattcacttc
    10621 tggtgaataa atgaaatctg tttctaaagc agatatgtct tttggtaggt caattacaac
    10681 tggccctgga cggcctgtag ttgcgatatg gacagcttcc gtaatgatac gcggaatatc
    10741 agctgtctca cgaacttgat aattgtactt agtgattggc atggtaattc ctacgatgtc
    10801 tgcctcctga aaggcatcct tcccaatccc tgctcgcgcc acctgacctg taaagaccaa
    10861 aaggggaacg ctatcgctca tagcatccgc aatccctgta atggcatttg ttgctcctgg
    10921 tccactagtg acgacggcaa cacccaactt tccagttgat ttggcataac cttcagcttc
    10981 atgcaaacaa ccttgctcat ggcgccctag aatgtggcga atgcctttaa aattatatat
    11041 cgcatcataa aaaggcaaaa ccgcaccacc aggataacca aagatggtat caactcctaa
    11101 atcacgaagt gtttccaaaa ctaggtccga ccccgtctta ggagattcta aactgatttt
    11161 ctccattgtt cccctttctt tcctcttaaa aataacttgt tactatcata ccattttttc
    11221 aaaatttttc aagataaaag aagaaatttt ctgaattttc tattttaacg tttatttatg
    11281 aatattattt ttatttttat ttaaaagata ccgatttcat ttactaaaaa agaaaaaaga
    11341 actgatttct cagtccttca ttaatcttat tccacactaa ataggtatgg gtaaacaggt
    11401 tgttgacctt ggtgaatctc gacttcaacg tcttcgaatt cttctacgat ttcttgagcg
    11461 atttcattgg caagttcttc gcttccgtct tcaccgacat agaaggttac gatttcactg
    11521 tcttcatcca acatatgttt caaggtttca gtcaatgttt ggtgcatatc agggtttgac
    11581 acaagaattt ttccatccac catacctaga ttatcgtttt catggatttc taagccatcg
    11641 atcgttgtat cacgcacggc tgttgtgacg cttccgctaa cgacatcgct aagagcagct
    11701 gtcatacgct cttggttttc ttcaatggac ttgcttggat caaaggcaag aagacttgtc
    11761 ataccttgag gaagagtgcg agcctctacc actactgctg gttgctccaa aacttctgcc
    11821 gcagattgag ctgccatgaa gatgttcttg ttgtttggca agaagatgat gttacgggca
    11881 ttgacctgtt caacagcctt gataaagtct tctgttgaag ggttcatggt ttgaccgcct
    11941 tcgataacat agtccacgcc ttgagaacag aagatatctg ctagaccttt accagccacc
    12001 acagcaatta aagcatactc tttttcttca gccgacttga taacttgagt agcttctttc
    12061 tcaacctgtg cttcgtgttg gttacgcata ttgtcaactt ttaccttgac caagctacca
    12121 tatttgagac cttcttgcat aacaagtcct ggatcttctg tatgaacatg gactttgaca
    12181 atttcatcat cgttaacaac gaggagagaa tccccaagct catccaagta gttacggaat
    12241 tcatcgtaat caaaatcttt agcataggtt ggaccttgct taagagctac catgatttca
    12301 gtacagtaac caaacgtgat gtcctcagtc gctacgtgac cagctacaga cttatgatgc
    12361 tctacattga tcatctcact catgttggca ggagtcgcta caaagtcctc agatgcaata
    12421 tattcgccag taagggctga aaggaaacct tcgtagatga agaccaatcc ttgaccacct
    12481 gagtccacaa cgccaacttc tttcaatact ggaagcatgt ctggtgtttt agctagagct
    12541 gttttagcac cttccaaggc tgcgcgcatg acttcaacag tgtcatctgt ttgctcagct
    12601 tttttcttag caccgatagc agctccacga gaaactgtca aaatcgttcc ttcaacaggt
    12661 ttcatcactg ccttataggc aacttccaca cctgattgga aggccagagc caagtcttga
    12721 cctgttaact cgtctttatc cttgatagct tgggaaaatc cacggaaaag ctgagacgta
    12781 atcactcctg agttcccacg cgcacccatc aaaagccctt tagcaagaat gctcgctact
    12841 tctccaactg tagaagctgg cttgtctgca acttctttag caccattttc aatggtcatt
    12901 cccatatttg tcccagtatc tccatctgga actggaaaga cgtttaatga attgacatat
    12961 tcagcttgct tattcaagcg agttgatgca gcctgcacca tttcttgaaa taagctagta
    13021 gtaatttttg acacggttat tctcctacaa ctttgatatt ttgaatgtag acatttacag
    13081 tctgagcagt aattccaagc tggttttcca agctaaaggc aacacgctct tgaatgtttt
    13141 ttgacacttc actaatcttt gttccgtagc ttaacacggt atatacatca actgcaatac
    13201 tgccatcttc ggctgccttt acgacgacac ctttagaata attttcctta cctagcaggg
    13261 cttggaaatt atctttgagg gcatttttac tagccatacc gaccacacca aaaatctcag
    13321 ttgctgctcc acctacgacg gttgcaatca cttcatctgt tagttcgatt tgaccatctt
    13381 ttgtattaat ttttacagtc atccttttta cctcaactag ttgatactct attttatcat
    13441 atttcagccc aagtgtaaaa gcagaatgat gtatcagcgg atatttactc tatttttcaa
    13501 acgatgttat acccacaata aaagaaaaaa gaccctaagg tctcctttgc ttttattatt
    13561 aaacgcgttc aactttacct gatttcaaag cacgagctga agcccaaact tttttaggtt
    13621 taccatcgat aagaacagta actttttgaa ggtttggttt tacggcacgt tttgtttggt
    13681 tcatcgcgtg tgaacggttg tttcctgata cagtcttacg acctgtaaag taacatactt
    13741 tagccattgt gttttcctcc tattagatct aatatagcgg atgtgctagc accacatacc
    13801 gtactatgtt atcacacttt cttgtttttt gcaagggaat tggaagattt tttatttgtg
    13861 tcttaaatca ggtcttgcgt gacattttct gctctccaca tgccattgtt gattaacaga
    13921 acaccagaat taaaattatg tgtataaaaa tcatctctaa ctgcagctaa gggtatagcc
    13981 gtcaagtcca aatcccacag ctcatctatc gattttctta caacaatatc taaatccaaa
    14041 tacagtacac gagactcgct tacatacttt ggaataaaat acctaaaaaa gccgcatatg
    14101 aaagtccctc aaaggggaga cgataacctt tcagaatact actgtcaatc taaacattca
    14161 caatctcact attcaaagtc tctagtcttt tttccatcaa ttggaaccat tctcgcggaa
    14221 ggtcatcatt aaaaacataa aacttaagat tataatagat gaacacaaag agattttatt
    14281 gttgtttcaa ctttatccat ataagcatta tctgcaccta agacaatcgc ttttttctct
    14341 tctttcactc tttatctcat ttctttttat tcccatcata tgtttctacg taaccattat
    14401 tttcgcccat tcgttcgtaa aaccatacca gtggagattt tagatgaagt cccattacgg
    14461 tttacaattt ttacattacg acacggagtt ttacaaatcg atttcatttg ccaaacgtag
    14521 ttagtaaggc agttagctag ttcgccaaat agcgactagc gtccaacaat ttggaacttt
    14581 agttccaatt gttggtactg agtcacatct tctcctctaa ctctacgtct ggatacttgt
    14641 ccgcaaacca gcggagggca aagtcatttt caaagagaaa gactggttgg tcaaaacggt
    14701 ctttggctaa gatattgcga cttgacgaca tccgttcatc caagtcctca ggcttgatcc
    14761 aacgaacggt ctttttaccc attgggctca tgaccacttc cgcattgtat tcgccttcca
    14821 tacggtgttt aaagacttca aactggagtt gaccaacagc tcccagcatg tactcacctg
    14881 tttggtaatt cttataaagc tgaacggctc cttcttgcac caattgctca atccccttgt
    14941 ggaaggattt ttgcttcata acattcttag cagaaacttt catgaaaatt tcaggagtaa
    15001 aggttggcag tggttcaaat tcaaacttgt tttttccaac cgtcaaggta tccccaacct
    15061 gataagtacc ggtatcgtaa accccgataa tatcacctga tacggcattg gtcacattct
    15121 cacgactctc cgccataaac tgggtaacat tagatagttt ggcaccctta ccagtacgag
    15181 ggagattgac actcatgcca cgctcaaatt cgcctgatac gatacggaca aaggcaatac
    15241 ggtcacggtg acgaggatcc atgttggctt ggattttaaa gacaaagcct gagaaatcct
    15301 tgtcataagg atccacaatt tcaccgtctg ttttcttgtg accatgtggt tctggagcaa
    15361 acttgaggaa gatttcaagg aaggtctgca caccaaagtt tgtcagggct gaaccgaaaa
    15421 agacaggcgt caattctcca gccagaatag cttcctctga aaactcattc ccagcttcat
    15481 ttaaaagctc aatgtcatcc ttgacttgct cgtagaaagg attgctacca aagagtttgt
    15541 ccccgtcttc tagactggca aaacgctcat cccctttgta aagctctaaa cgttggttat
    15601 agaggtcata caagccctca aaggctttcc ccatcccgat aggccagttc atagggtagc
    15661 tagcaatgcc caagatttct tccaattctt gcaagagatc caaaggctca cgaccgtcac
    15721 ggtccagctt gttcataaag gtaaaaactg gaatgccacg atgtttcaca acctcaaaca
    15781 atttcttggt ttgagcctcg atccccttgg cagagtccac gaccatgacc gcagcatcca
    15841 ccgccatcaa ggtacgatag gtatcttctg agaagtcctc gtgccctggc gtgtctaaga
    15901 tattcacgcg cttgccgtcg tagtcaaatt gcataacaga tgaagtaaca gaaatcccac
    15961 gttgcttctc gatatccatc cagtcagatt tagcaaaagt ccctgttttc ttccctttta
    16021 ccgtaccagc ctcacgaatc tcacccccaa agtagagtaa ctgctcagtg atggttgttt
    16081 tccccgcgtc cgggtgggag ataatggcaa aggtacgacg tttcttaatt tcttcttgaa
    16141 tattcataag ttctctttct ttgattctct atttttcttg tttcaatagc tgagaatgat
    16201 ttttacattg gattttacca ttcctttcaa cattccatta tatcggattt tagcattttt
    16261 ttcaatttct atttcttttc acttccccct cccttattta taggaaaata tggtaaaata
    16321 gaacagacta aaaatcatca tttcacgaaa ggatgcaaga tgaaaattac gcaagaagag
    16381 gtaacacacg ttgccaatct ttcaaaatta agattctctg aagaagaaac tgctgccttt
    16441 gcgaccacct tgtctaagat tgttgacatg gttgaattgc tgggcgaagt tgacacaact
    16501 ggtgtcgcac ctactacgac tatggctgac cgcaagactg tactccgccc tgatgtggcc
    16561 gaagaaggaa cagaccgtga tcgcttgttt aaaaacgtac ctgaacaaga caactactat
    16621 atcaaggtgc cagctatcct agacgatgga ggagatgcct aatgactttt aacaataaaa
    16681 ctattgaaga gttgcacaat ctccttgtct ctaaggaaat ttctgcaaca gaattgaccc
    16741 aagcaacact tgaaaatatc aagtctcgtg aggaagccct caattcattt gtcaccatcg
    16801 ctgaggagca agctcttgtt caagctaaag ccattgatga agctggaatt gatgctaaca
    16861 atgtcctttc aggaattcca cttgctgtta aggataacat ctctacagac ggtattctca
    16921 caactgctgc ctcaaaaatg ctctacaact atgagccaat ctttgatgcg acagctgttg
    16981 ccaatgcaaa aaccaaaggc atgattgtcg ttggaaagac caacatggac gaatttgcta
    17041 tgggtggttc cggtgaaact tcacactacg gagcaactaa aaacgcttgg gaccacagca
    17101 aggttcctgg tgggtcatca agtggttctg ccgcagctgt agcctcagga caagttcgct
    17161 tgtcacttgg ttctgatact ggtggttcca tccgccaacc tgctgccttc aacggaatcg
    17221 ttggtctcaa accaacctac ggaacagttt cacgtttcgg tctcattgcc tttggtagct
    17281 cattagacca gattggacct tttgctccta ctgttaagga aaatgccctc ttgctcaacg
    17341 ctattgccag cgaagatact aaagactcta cttctgctcc tgtccgcatc gccgacttta
    17401 cttcaaaaat cggccaagac attaagggca tgaaaattgc tttgcctaag gaatacctag
    17461 gcgaaggaat tgatccagag gttaaggaaa caatcttaaa cgcggccaaa cactttgaaa
    17521 aattgggtgc tatcgtcgaa gaagtcagcc ttcctcactc taaatacggt gttgccgttt
    17581 attacatcat cgcttcatca gaagcttcat caaacttgca acgttttgac ggtatccgtt
    17641 acggctaccg cgcagaagat gcgactaatc ttgatgaaat ctatgtaaac agccgtagcc
    17701 aaggttttgg tgaagaagtg aagcgccgta tcatgctggg tactttcagt ctttcatcag
    17761 gttactacga tgcctactac aagaaggctg gacaggtccg tacacttatc attcaagatt
    17821 tcgaaaaagt cttcgcggat tacgatttga ttttgggtcc aactgctcca agtgttgcct
    17881 atgacttgga ttctctcaac catgacccag ttgccatgta cttagccgac ctcttgacca
    17941 tacctgtaaa cttggcagga ctgcctggaa tttcgattcc tgctggattc tctcaaggtc
    18001 tacctgtcgg actccaattg attggtccca agtactctga ggaaaccatt taccaagctg
    18061 ctgctgcttt tgaagcaaca acagactacc acaaacaaca acccgtgatt tttggaggtg
    18121 acaactaatg aactttgaaa cagtcatcgg acttgaagtc cacgtagagc tcaacaccaa
    18181 ttcaaaaatc ttctcaccta cttctgccca ctttggaaat gaccaaaatg ccaacactaa
    18241 cgtgattgac tggtctttcc caggagttct accagttctc aataaagggg ttgttgatgc
    18301 cggtatcaag gctgctcttg ccctcaacat ggacctccac aaaaaaatgc actttgaccg
    18361 caagaactac ttctaccctg ataatcccaa agcctaccaa atttctcagt ttgatgagcc
    18421 aatcggttat aacggctgga ttgaaatcga gctagaagac ggtacgacca agaaaattgg
    18481 tatcgaacgc gcccacttag aggaagacgc tggtaaaaac acccacggta cagacggcta
    18541 ctcttacgtt gaccttaacc gccaaggggt acctttgatt gagattgtat ctgaagccga
    18601 tatgcgttcg ccagaggagg cctatgctta tctgacagcc ctcaaggaag ttatccagta
    18661 cgctggcatt tctgacgtta agatggaaga aggttctatg cgtgtggatg ccaacatctc
    18721 ccttcgccct tatggtcaag aaaaattcgg taccaagact gaattgaaga acctcaactc
    18781 cttctcaaac gttcgtaaag gtcttgaata cgaagtccaa cgccaggctg aaattcttcg
    18841 ctcaggtggt caaatccgcc aagaaacacg ccgttacgat gaagctaaca aaacaaccat
    18901 cctcatgcgt gtcaaggaag gggctgctga ctaccgctac ttcccagaac cagacctacc
    18961 cctctttgaa atttctgacg agtggattga ggaaatgcgg actgagttgc cagagtttcc
    19021 aaaagaacgt cgtgcgcgtt atgtatctga ccttggttta tcagactacg atgctagtca
    19081 gttgactgct aataaagtca cttctgactt ctttgaaaaa gctgttgccc taggtggtga
    19141 tgccaaacaa gtctctaact ggctccaagg ggaagtcgct cagttcttga atgctgaagg
    19201 taaaacactg gaacaaatcg aattgacacc agaaaacttg gttgaaatga ttaccatcat
    19261 cgaagacggt actatttcat ctaagattgc caagaaagtc tttgtccatc tagctaaaaa
    19321 tggcggtggc gcgcgtgaat acgtggaaaa agcaggtatg gttcaaattt cagatccagc
    19381 tatcttgatc ccaatcatcc accaagtctt tgccgataac gaagctgctg ttgccgactt
    19441 caagtcaggc aaacgtaacg ccgacaaggc ctttacagga ttccttatga aggcaaccaa
    19501 aggccaagcc aacccacaag ttgcccttaa actacttgca caggaattgg cgaagttgaa
    19561 agaaaactag acagaacaaa accagcccta aggttggttt tttcttctct accaactccc
    19621 aataactatt ttggctttat ttccagagta ttttatggta aaatgaagag taataatatt
    19681 tattaaagag gtaaaaacat gattgaagca agtaaattaa aagctggtat gacctttgaa
    19741 acagctgacg gcaaattgat tcgcgttttg gaagctagtc accacaagcc aggtaaagga
    19801 aacacgatca tgcgtatgaa attgcgtgat gtccgtactg gttctacatt tgacacaagc
    19861 taccgtccag aggaaaaatt tgaacaagct attatcgaga ctgtcccagc tcaatacttg
    19921 tacaaaatgg atgacacagc atacttcatg aatacagaaa cttacgacca gtacgaaatc
    19981 cctgtagtca atgttgaaaa cgaattgctt tacatccttg aaaactctga tgtgaaaatc
    20041 caattctacg gaactgaagt gatcggtgtc accgttccta ctactgttga gttgacagtt
    20101 gctgaaactc aaccatctat caaaggtgct actgttacag gttctggcaa accagcaacg
    20161 atggaaactg gacttgtcgt aaacgttcca gacttcatcg aagcaggaca aaaactcgtt
    20221 atcaacactg cagaaggaac ttacgtttct cgtgcctaat ctctagaaag aggtcattct
    20281 atgggaattg aagaacaact tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc
    20341 attgctatcg ctactgcaaa ggtagagggt gttcactctt tttcaaacag atcagtgtct
    20401 gatacccttt caaaactttc actcggccgt ggcgtttatc ttaaaaacgt ggacgaagaa
    20461 ctcacagcag atatctatct ctaccttgag tacggagtaa aagttcctaa ggtagcggtt
    20521 gctatccaga aagctgtcaa agatgccgtc cgtaatatgg ctgatgtaga actcgctgct
    20581 atcaatattc acgttgcagg tatcgtccca gataaaacac caaaaccaga attgaaagat
    20641 ctatttgacg aggacttcct caatgactag tccactatta gaatctagac gccaactccg
    20701 taaatgcgct tttcaagctc tcatgagcct tgagttcggt acgaatgtcg aaactgcttg
    20761 tcgtttcgcc tatactcatg atcgtgaaga tacggatgta caacttccag cctttttgat
    20821 agacctcgtt tctggtgttc aagctaaaaa ggaagaacta gataagcaaa tcactcagca
    20881 tttaaaagta ggttggacca ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt
    20941 gggagttttt gaaatcactt catttgacac tcctcagctg gttgctgtta atgaagctat
    21001 cgagcttgca aaggacttct ccgatcaaaa atctgcccgt tttatcaatg gactgctcag
    21061 ccagtttgta acagaagaac aataaaaaga aaaagtgttt gatatctatc aaacactttt
    21121 tctttgcctc ccactatcta aaaaaatgat aatagatata attgtaaaca aaaatccaga
    21181 taggttttgc atgattgaga aagttaaaaa aactatggca gagaatcgtt aatctcagat
    21241 tgtcggtaga acgataaaca agggcaaaaa agaaaccaat cagactataa tataataaac
    21301 taattggatc tctgtgagat agtatcaaat ggctaatccc aaagataagg cctgataaga
    21361 tgacatctaa atagtacttt gacttaggaa agaaggtatt catcaaatac cctctatcaa
    21421 gagtctcctc aaaaacagga ccgatgatta caagcaggac aaaagataag atagtcgata
    21481 aaaaggttgg ttgtccattt gaaagaacca cggtaaaata ctcatcatga atattcctat
    21541 ggttaatcaa atgagcatag cgtgcctaaa aattaccgag aatctgataa accacatacg
    21601 ttgcaaataa gtagaagaca aatgaccagt tccagctctt tttttcaaag ataaagagca
    21661 tctttttctt ttttaacctc caaatcaata gaaggaaact tcccactaat accattgtta
    21721 aaataagaga atagacatca gctcctaacc ctaaaatgat cgtcacatac aatccaattg
    21781 tttgtggtaa ataggtagat agtaaaataa taagcaaaaa tattccaaat tgtcttagtt
    21841 tttttgtgtt tctcatcgta cttttttgaa agattaccct gctcggaagc cgtacttcca
    21901 agcatctata taagaattaa gtgccccttg cctcatatag ggagcaaatt ctctataata
    21961 taaccatcta ctatatccat cttcccaaac agcaagacca cctgaagttt gctccaagtc
    22021 ctcagttgaa agaactgtaa atgtatttgt acctgtcatt gcaagtacct tcttaaaata
    22081 gattgttgta ggctcacatt tatagtatat ttcttttttt gtctatttta tagtctatct
    22141 cctcaactgt caatttttca acctgaattg catttttcca taaaaaatga gacctttcta
    22201 gtctcattta gtcattctta gtattttcta aatcgttgat agcgttcttc cagcaactct
    22261 tctagcggtt tttgtgaaag tctagccagc tccgtttgga gttctttttt gacactctta
    22321 atcagttctt tactagaaag tcctacttca gaaatcacct tatccaccac gtccatttct
    22381 aacagttcat gcgaagtgat tttcatcagt tctgctgctt ccatggcgcg agtaccgtcc
    22441 ttccataaaa tggaagcaaa gccttctgga ctgagaatgg catagataga attttccagc
    22501 atccagacac ggtccgcgac agctagagcc agagccccgc ctgaaccacc ttcaccgata
    22561 ataatggcga taataggaac tttcaggtca ctcatttcca tgagattgcg agcgatagct
    22621 tccccttgac cacgttcttc tgctccgaca ccaggataag cacctgctgt attgataaag
    22681 gtcacaactg gacggccaaa tttctcagcc tgtttcatca accgcagtgc ctttcggtaa
    22741 ccttctggat gtggttggcc aaaattccgt ttgaggttgt cttgcaaact cttgcctttt
    22801 tggataccaa ccactgttac agcttggtct ccaagccaac caataccacc aacaactgca
    22861 ccatcatcac gaaaagaacg gtcaccatgt aattggataa attcatcaaa aatgcctgtc
    22921 gcaaagtcca aggttgtcaa gcgactctgc tcacgcgctt ctctgactat ttttgcaata
    22981 ttcatctagg actccctcca tgcaatctga ctaggctagc aatcgtatct ggtaagtctc
    23041 ttcttttgac aatagcatcc acaaagccat gttctaatag gaattctgcc ttttggaaat
    23101 cctcaggcaa gctttcacga accgtatttt caatcacacg acgtccagca aaaccaacca
    23161 agctctgtgg ttcagccaga atgatatcgc cttccatagc gaaagaagct gtcacaccac
    23221 cagtcgttgg atctgtcaaa atggtcaggt aaaagagacc agcatttgaa tggcgtttaa
    23281 ccgccgcaga gatcttagcc atctgcatga gactcatgat tccttcctgc atacgggctc
    23341 caccagaggc tgtgaatagg acaactggca atttttcgac agtcgcatac tcaaacaaac
    23401 gagtgatttt ttcacctaca accgtaccca tagaagccat gataaagtta gaatccataa
    23461 tcccaagagc cacagtctga cctttaataa gagcagttcc tgtcacaacg gcttcatgca
    23521 gacctgtttt ttcacgcata gatgccagtt tcttttggta accagggaaa tgcaagggat
    23581 ccttgctttc aatccctgta aacaattctt tgaaggttcc catatcaatc gtcaaagcca
    23641 agcgttcttg ggcagaaata cgaaaggtat agctacagtg cggacagata cgttcacttc
    23701 ccagatcctt ctgatagatg gtatgcttac agcctggaca ctgggaaaat aattcatctg
    23761 gaacctctgg cttagcttga ggtttttccc taaccgaacg attgggattg attcgaatat
    23821 acttatcttt tttactaaat agagccattg attccccttt tcggtttaaa ctcttaaagt
    23881 cattttattc tttttcttga tatttaggta agaaggtttc catcaagaag gaagtatcat
    23941 aatccccagc aatgacattg cgatctgaaa tgaggtcaag ctggaaatct gcattggtct
    24001 gcactccttc aatctctaat tcatagaggg cacgttgcat tttcatcaag gcgtcaaaac
    24061 gattttcgcc gtgtactatg attttggcaa tcatactatc ataataaggc ggaatggtat
    24121 aacctggata aactgctgaa tccacgcgca agccaactcc accacttggc agatagagat
    24181 tagtaatctt acctggactt ggagcaaagt taaaggctgg gttttctgca ttgatacgac
    24241 actcgatggc atgaccgcgt aggacaatat cttcttgctt aacagacaaa ggctgacctg
    24301 ccgcaatgca aatctgttcc ttaacgatat caacacctga aacaaactct gttactggat
    24361 gttctacctg aacacgagta ttcatctcca tgaaatagaa attgctactt gcttcatcaa
    24421 gaagaaattc aatggttcct gcattctcat agccaacaaa ctctgccgct cgaacagcag
    24481 cagcacctat ttcatgacgc agcgtttttc cgattgcaat cgagggactt tcttccaaaa
    24541 ccttttggtt attcctttga agagaacaat cccgttcacc caagtgaatc acatgtccat
    24601 gctcatcacc taggatttga acctcaatgt gccgagctgg atagataacc cgttctatgt
    24661 acatggcacc attgccataa ttggccttgg cctcactaga ggcagtttca aaggcagaaa
    24721 cgaggtcatc tggtttttca accttacgaa tccctttacc acctccacct gctgaagcct
    24781 tgagcataac aggatagcca attttttcag caacaatcaa agcttcttca gagttatgca
    24841 cttctccatc tgaacctggt ataacaggca cacctgcttt aatcatctga gcacgcgcat
    24901 tgatcttatc ccccatcata tccataacat gaccagatgg accgataaac ttgataccta
    24961 cttcttcaca catggtcgca aatttggaat tttcactgag aaatccaaaa ccagggtgaa
    25021 tagcttctgc ctcagtcaag actgcagctg atagaactgc attaatattg agataagact
    25081 ctgttgcctt gccaggacca atacaaactg cttcatctgc caacagcgta tgaagagctt
    25141 ccttatcagc agttgaataa accgctaccg tcgcaatccc caattcacgt gccgcacgga
    25201 taatacgaac cgcaatttca ccacgattgg caattaaaat ttttcgaaac atggagaacc
    25261 tccttagttc ccaattgcaa aagtaagggt accactggct gcaagcttgc catccacttc
    25321 agcctttgct tcaaccacag ctatggtgcc acgacgtttt acaaaagtcg ctgtcataac
    25381 caattggtcg cctggtacaa cttgcttctt gaacttaacc ttatccatac cagcgtaaaa
    25441 gaccagtttt cctttatttt caggttttga taactccaac acaccagcag tttgcgccaa
    25501 ggcttccata atcagaacac ctggcataac tgggtattga ggaaagtggc cgttaaagaa
    25561 aggctcgttg atggtcacat ttttgatagc aacaatggta tcctcgctca cctccaagac
    25621 acggtccact agaagcatag gataacggtg gggaagggct tctttgattc cttgaatatc
    25681 gatcatttga tacgtaccaa tcctttacca aactcaacca tttcttcgtt agagacgaga
    25741 atttccgtta ccacaccatc cttaggagct gggatttcat tcatgacttt catggcttcg
    25801 ataattacca atgtttgacc ttttttgaca ctatcaccaa ctgtaacgaa ggcaggttta
    25861 tctggtccag cagccaagta aaccactcca acaagtggac tctctacaag atttccctca
    25921 ctagccacac ttgcttcagc tggagctgga acttcttctg ctacagtctc tgctggagca
    25981 gatgtaggag ctactggact cggtgttgct agaacgggtg ctggagcgac ttgagttgca
    26041 acttcaggca caggtctcgc ttcattcttg ctaaactgca actcatccgt cccattttta
    26101 taagaaaatt ctctcaaact tgactggtca aattgagtca tcaagtcttt aatatcgttt
    26161 aaattcatac ttatctattc tcccaacgtt tgaaagcaag aactgcattg tggcctccaa
    26221 aaccaaaagt atttgaaata gcgtatggaa tttctttctc caagccttgt ccataaacga
    26281 cattagcttc gatataatct gatacttcac ttgtcccagc tgtcattggt acaaagttat
    26341 gacgcatagc ttcgatggtg acgatagctt ctactgcacc cgcagccccc agcaaatgtc
    26401 ctgtaaaaga cttggttgat gatacaggta cttccttacc aagaacagct acgatagcac
    26461 cactttctcc tttttcattg gcaggagttg acgttccgtg agcattgaca taggctactt
    26521 gctctggaga aatctcagct tcttccaagg ctagtttgat ggccttgata gctccctgac
    26581 cttctggatg tggagaagtc atgtggtagg catcacaagt atttccgtaa ccaaccactt
    26641 cagccaggat agtagctcca cgtttttcag cgtgttcaag actttctaga accaacatcc
    26701 ctgaaccttc acccataaca aagccattgc gatccttatc aaatgggatc gaagcacgag
    26761 ttggatcctc tgtagtagag agagctgtta aggcttggaa accagcgatg gcaaaaggtg
    26821 tgatagaagc ttctgttcct cccaccaaca tcacatcttg gaaaccaaac ttaatggagc
    26881 ggaaggcatc cccaatcgca tcatttgatg aagagcaggc agtattgata gatttacaaa
    26941 caccgtttgc accaaaacgc atggctacat tcccagaagc catatttggt aaagcttttg
    27001 gaagagtcat tggtttgaca cgtttgggtc ctttttcatg aaggcgaagt acctgatctt
    27061 caatttcctt gattccacca ataccagatg caacgataac accaaaacga tccctattaa
    27121 gagcctctac atcaagattg gcatgattta cagcctcttg ggctgcatac aaggcatata
    27181 aagaatagtt atcaaaacgg ttggtatctt tttttacaaa gtatttatcg aacggaaaat
    27241 cttggatttc tgccgcatta tgcacatcaa agtcactatg atcaaatttt gtaatgccac
    27301 caatgccgat ttccccagtt gctaaactat tccaaaattc ttctggtgta tttccgattg
    27361 gagatgttac tccataacct gttaccacta ctcgatttag tttcattctt ttcacctcta
    27421 gctttcgcta catacttaag ccaccatcaa tggcaaccac ttgaccagtt agataatctt
    27481 ggcctgctaa aaatactgtc aaatctgcaa cctgctctgc ctgcccaaat tctttcatcg
    27541 gaatctgagc tagtgtagct tccttaatct tatctgataa gatagctgtc atatcagact
    27601 caatcattcc tggagcaatc acattgactc gtatattccg actagcgacc tcgcgtgcca
    27661 cagacttggt aaagccaatc aagccagcct tagaagcagc atagttagct tgaccaatat
    27721 tccccatcaa accaacaaca ctagacatat taatgatagc accttctctg gctttcatca
    27781 tcggtttcaa gactgattgt gtcatattaa aggcaccagt cagattgacc ttgagcactt
    27841 tttcaaaatc tgcttctgtc atcttgagca taagagtatc ttgggtaatc cctgcattgt
    27901 tgaccaaaac atctactgaa cccagttctg caatagcttg atcaatcata cgcttagcgt
    27961 ctgcaaaatc tgatacatct cctgaaatgg gaaccacctt gataccatag tttgaaaact
    28021 cagcgagcaa ttcttctgag attgccccac gactgtttaa gacaatgttg gctcctgctt
    28081 gagcaaactt gtgggcgatg gcaagaccaa ttccacgact cgaacctgta ataaagatat
    28141 ttttatgttc tagtttcatt tttttccttt caaaacttct acttatttta gtctattttt
    28201 ctaaaagtgc tactaaactc gcttgatctt ccacatgagc taagtgagca gtttgatcaa
    28261 tttttttaac aaaacctgac aagactttcc ccggtccaat ctcgataaag ttgcttatgc
    28321 ctgcttcttg catgacccca atactttcat agaaacgaac gggttccttg acctgacgcg
    28381 tcaagagctg agcaatgtcc tctttttgca tcacagcagc ttctgtattg ccgactaggg
    28441 gacaagtaaa atctgaaaaa cttacctgag ctagagtttc agctagtttc tggctagcag
    28501 gctcaaggag agcggtgtga aagggacctg acaccttaag aggaatcaag cgtttggcac
    28561 ctgcttcttg caaaagttca accgctcgat caactgcaac cacttctcca gcaatgacga
    28621 tttgtgcagg tgtgttatag ttggctggag taaccactcc aagttcagaa gctttttgac
    28681 aggcttcttc aatgacctct actggcgtat tgagaactgc taccatcttg ccagagtcag
    28741 caggagccgc ttcttccata taggctccac gcttagctac caaggcaacc gcatcttcaa
    28801 aatccaaggc gccgcttgcc accaaggcag agtattctcc aagagacaaa ccagcaacca
    28861 tatcaggctg atagcccttt tcttgcaata aacggtagat agcaaccgaa gtcgctagaa
    28921 tggctggttg cgtatagcgg gtctgattga gtttgtcttc ttccgtatcg atgagataac
    28981 gtaaatcata accgagcacc tgactcgctc gatcaatcgt ttctttgaca atcggatact
    29041 gatcatagaa atcccgtccc atccctagat actgggcacc ttgaccagca aataaaaagg
    29101 ctgttttagt catttcttac aactcctgcc cagcgagagg cttcttcttg aattttctta
    29161 gcggctccgt aatacaaatc ttttaggatt tcttcagctg tttcttcttt agaaacaagc
    29221 cctgcgattt gacctgccat gacagagcca ccatccacat caccgtgaac aactgctttg
    29281 gctagggcac ctgctcccat ttgttcaaag atttctaaat caggatcttc ctgcttaaag
    29341 gcatcttttt cagccagttc aaaatctcta gtcaactgat ttttaatagc acgaacagca
    29401 tgaccaaagt gctgagctga aatcgtagta tcaatatccc ttgcttttaa aattttctcc
    29461 ttgtagtttg gatgggcatt cgactctttt gcaactacaa accgtgtccc cacctgtaca
    29521 gcctctgcac ctagcataaa gccagccgca gcaccttcac catccgcaat tcctcctgca
    29581 gcaataacag gaatagatat agctgtggct acctgtcgca ccaaggtcat ggttgttaat
    29641 ttaccgatat gccccccagc ttccattcct tctgcaataa cagcgtctgc accgattttt
    29701 tccatgcgtt tagctaaagc gacactagga acgacaggaa taacgattat cccagcttca
    29761 tggaaacgtt ccatatactt gcttggattt cctgctcctg ttgtgacaac tttaacacct
    29821 tcttcaataa cgagatccac gatatcttcc acaaagggag ataagagcat gatgttgacc
    29881 ccaaagggtt tatcagtcaa tgatttgatt ttatcaatat tagccttgac aacttctttc
    29941 ggggcatttc ccccaccgat aattcctaat cctccagcct tggaaacagc ccctgccaaa
    30001 tcaccatcag caacccaggc catccctcct tggaaaatag gatagtcaat cttcaataat
    30061 tctgtaatac gcgttttcat agtgcctcca accttccttg cttacgtaat agttcgattt
    30121 caccataatt tgacagtcaa actattacct aaacaagagg gagtgggttt ctccctactc
    30181 cttctactaa tattctgctt attttgcttg ctcttcaacg taagcaacca agtcaccaac
    30241 tgttttcaag tcattttctg cttcgatttg gatatcaaaa gcatcttcga tttctgagat
    30301 tacttggaac aagtccaatg aatctgcgtc caaatcatca aaagttgatt caagtgttac
    30361 ttctgatgcg tcttttccaa gttcttcaac gataatttct tgtacttttt caaatactgc
    30421 catgatagga ctcctttaaa ataaatagtt tttttataac aatgtgttca ccacatgatt
    30481 acctaaattg taagaatgag cgtgccccag gtcaagcctc caccgaagcc tgatagaaga
    30541 acagtctggc taccatctaa agggatgaga ccttgttcta cacactctga aagtaaaatc
    30601 gggatactgg ctgcactggt attgccatat tccatcatat tggctggaag tttggctcgg
    30661 tcaacaccaa tttttctagc catcttatcc aaaatacggt cattggcttg atgaagtagc
    30721 agataatcca agtctgtcac ctctatagga gattcatcaa tagtctgctt gatagacttg
    30781 gctacatctc gaatggcaaa atcaaagact gtgcgtccat ccatcttcaa aaacgaatct
    30841 gcactttctt gatctgaaaa tggagaatgc aaacctgaat gcccataagt taaacactca
    30901 ctgcgacttc catcgctatt gaggctctca gctaagaaat gctcttgctc gctagcttct
    30961 aacaagacac caccagcacc atctccaaac aacacagctg ttgatcgatc cgaccaatcg
    31021 actgccttag agagggtttc actaccaatc accaagcctt tttgaaagcg accagaagcg
    31081 ataaactttt cagcagttga aagagcaaat acaaatccac tgcaagccgc ggttaagtca
    31141 aaagcaaagg ctttattagc accaatatta gcttgaacac gagcagctgt agagggcatc
    31201 atcgaatctg gagtaatggt agctaggatg ataaaatcca gctcttctcc tgttattcca
    31261 gcttttgcca tcagtttctt agcaacctct gtagccaaat cactggtaga ttctgttctt
    31321 gaaatatgcc tttgtcgtat tcccgttcga cttgaaatcc actcatcatt ggtatccata
    31381 atctgagcca agtcgtgatt tgtaaccact tgctctggca cataatgagc aacctgactt
    31441 atttttgcaa aagccattat ttcaaatcct ccaaaaattg gtaaagatta gtcaagcctt
    31501 tacccatgac agcaatttct tcctcgctca tgccatcaat aattttttct accatggcct
    31561 tgtggaagcg tttatgcagt ctatgaatca agcgaccctt ctttgtcaaa tgcagatgca
    31621 ccacacgacg atcctgttct gaccgaactc gctcaatgta gcccttacgc tctaaattgt
    31681 tcaaacttgt cgtaacagtt ccaagagtta ccatcaactc ttttgacact tgacttggag
    31741 tcacatctgg agccttaccg atgacatcaa tcgtatgcat ttctttgatg gagatatcct
    31801 taaaacgact acctctcaag ttcacttcct caattacaag gacattgtta aatatagatg
    31861 ttaaatattc attgattcgt tggtagtcca tttttcatat ccctccttct tcaaaaaact
    31921 tttacaatca aaacatttga cagaaagaat tatatcaaaa ttcaaagaat gatgcaagta
    31981 ttttttattt tcctgtaaat ttaggtcttc ttctctccga atgagctcgc actccttctt
    32041 tgaaatcctc tgtttgagct aaggatttct gtaggttcaa ttctaaagta gcgtaaccct
    32101 gccagtcttt aaattggctc tcccaaacca acttcttaat ggcagcatag gaattacttg
    32161 aagcacgtct taatttttta agaagctgtt ctctcgtctt ttcaagtttt tcagcttcag
    32221 aaacgcggta aaccaacccc cattctaggg ctttttctgc cgttaaagcc tctcctgtca
    32281 tagctaattg agcagcacgc gtcacaccga tactgcggct caagagatga attccccctg
    32341 catctggagc caaaccaaca ccaacaaagg cttggataaa cttagcctta tccgtcgcca
    32401 aacagaaatc tgccgcaaca gccatattcg ctgcggcacc tgcaacagca ccgtcaactt
    32461 ccattaaaac aggtttggct atttgcttga ttttataaga aatcgtattg accaactctg
    32521 cgatttttgt caacgatgga atatcatcct catccactgc tcgcttcatc tctaccaaat
    32581 ctcccccaac tgagaagacc tttccattgg cattgattaa gataaaatgc acagctggat
    32641 tttcttctgc caaagtcaga gcttctaaaa tctcctcaca catgggaata tgaaaaccat
    32701 ttgcgacctc aggacggttc aaggtaagga ttgccaagtc ctcttcaagc tgataaataa
    32761 tgtgttccat cagggctcct ttttatttta taagcagttt atactcttcg aaaatctctt
    32821 caaaccgcgt cagcttccat ctgcaacctc aaaacagtat tttgagctga cttcgtcagt
    32881 cttatttaca acctcaaagc agtgctttga gcagtctgcg gctagcttcc tagtttgctc
    32941 tttgatttca ttgagtgtta aattatttca ctgtcaaagt atatcttttt taggagcaga
    33001 aagcaagaaa aaatcgactg aaagtgtctc agccgataag aaaggctcgc tttaggctag
    33061 aaagcatctt attttcttca ttgaaaaaag cctttctttc tgctataatc gtataaaata
    33121 cttactttag gagttcttat gaaagttgtt aaatttggag gtagttctct tgcctctgct
    33181 agtcaattag aaaaagtttt aaacatcgtc aaaagcgatt cagagcgtcg ttttgtagtc
    33241 gtttctgcgc ctggtaaacg caatgctgaa gatactaagg ttacggatgc cctgattaaa
    33301 tactaccgcg actatgttgc gggtaacgat attagcaaga gccaaagctg gattatcgac
    33361 cgctatgctg ctatggttag tgaattggga ctaaaaccag ctgtgctaga aaaaatttct
    33421 aaaagtattc acgccttggc cactcttcct attgaagaaa atgaatttct ctacgatact
    33481 ttcctagcag ccggtgaaaa taacaatgcc aaattgattg ctgcctactt taaccaaaat
    33541 ggtatcgatg cacgctatat gcaccctaga gaagctggga ttgtggtcac aagtgaacct
    33601 ggtcacgctc gcatcattcc atcaagttat gacaagattg aagaattgac aaacaccaat
    33661 gaagtccttg tcattcctgg tttctttggt gtcactaagg aaaatcaaat ctgtactttc
    33721 tcacgtggag gttctgatat tacaggttct atcattgctg ctggtgtcaa agctgacctc
    33781 tatgaaaact ttacggacgt tgatggtatc tttgcagctc accctggtat tatccaccaa
    33841 ccacactcga ttcctgagtt gacctaccgt gaaatgcgcg agttggccta tgcaggcttc
    33901 tcagtccttc atgacgaggc tcttcttcct gcctaccgtg gaaaaattcc tctggttatc
    33961 aagaatacca acaaccctga ccatccaggt actcgtatcg ttctaaaaca cagtaatgat
    34021 gaatttccag ttgtgggaat tgctggtgac tcaggctttg tcagcattaa catgtcgaaa
    34081 tacctcatga accgtgaggt tggatttggc cgcaaggttc tgcaaatcct ggaagaactt
    34141 aacatcggtt gggaacatat gccaacaggt atcgacgatc tttctatcat tctccgttct
    34201 cgccaactaa ctcccatcaa gaaagaagaa atcctgcgtc agttggttca aaaggctaaa
    34261 gtagatcatg cagaaatcga acacgacctt tctatcatta tgattgttgg tgaaaaaatg
    34321 aagagccata tcggagtgac tgctactgcg acacgcgctc tatctgaaaa caaaatcaac
    34381 atccagatga tgtctcaagg ttctagtgaa gtttctatta tgtttgttgt caataaagac
    34441 caagagaaag cagcaattaa agccctctac aatgcctttt ttggagaaag taaggaagac
    34501 taagcatggc tcaatcactt aacaaaacag tactcctcag tacaacaggc acttcctacc
    34561 tctctatagc tgggaaagtt gggaaattcc ttgtcggaga tcaggctttg gaattttacc
    34621 cagatgtcaa tgtcgaacaa tttatccaga ttccttggag ccatatcaat cagattggag
    34681 ccaatgtcac tggacgcaaa atcagccgcc acttcgaagt ctttacagac aaaggaaaat
    34741 tcctctttgc ttcaaaagac tcaggtgcca ttctcaaaat tgcacgcaaa aaactaggca
    34801 atgacaaggt cgtcaaactt ccgaccctga ttcagacaat tagccaaaaa tttaaaaatc
    34861 tatttgcaaa aaagtagaaa ctttagtata atcatagcaa cggataagta ggttatcttc
    34921 ttctttcaga aagtctgcgg gtactgcgag cagataggag ggataggtga aattctaccg
    34981 ttagtaacaa ttacatacac aatcaagtgc acacctgtga agttggatgg aaccgtggcc
    35041 ctgccactcc aacgttttgt caggtgtgct tttttcataa aggagttctt atgttagata
    35101 tcaaacgtat tcgtacagat tttgaagctg tcgcagaaaa attagctaca cgtggtgtag
    35161 atgctgctgt cttgaatgaa atgaaagaaa tcgatgctaa acgtcgtaac atcttggtca
    35221 aggttgaaac tctcaaagca gaacgtaaca cagtttctgc tgagattgcc caagctaagc
    35281 gcaacaagga aaatacagat gacaagattg ctgccatgca aaatctatct gctgaggtta
    35341 aagccttgga tgctgaattg gcagaaatcg atgctaaatt gacagaattt acaacgactc
    35401 ttccaaatat cccagctgac agcgttcctg ttggggctga cgaagacgac aatgtggaag
    35461 ttcgccgttg gggtactcca cgcgagtttg acttcgaacc taaagctcac tgggatctcg
    35521 gtgaagacct tggtatcctt gactgggaac gcggtggtaa ggtaacaggc gctcgcttcc
    35581 tcttctataa aggcctcggt gctcgtttgg aacgtgctat ctacaacttt atgttggatg
    35641 aacatggaaa agaaggctat actgaagtca tcacacctta catagtcaac catgattcta
    35701 tgtttggtac tggtcagtat ccaaaattta aggaagatac ttttgaactc agcgatacca
    35761 actttgtctt gattccaact gctgaagttc ctctggcaaa ctactaccgt gatgaaatct
    35821 tagacggcaa agatcttcca atctacttca ctgctatgag tccgtcattc cgttctgagg
    35881 ctggctctgc cggtcgtgat acgcgtggct tgatccgttt gcaccaattc cacaaggttg
    35941 aaatggtcaa atttgccaaa ccagaagaat cttacgaaga attggaaaaa atgacagcca
    36001 acgctgaaaa cattcttcaa aaactcaacc ttccataccg tgtcgttgct ctctctactg
    36061 gagatatggg cttctcagct gcgaagactt acgacttgga agtgtggatt ccagcacaaa
    36121 acaattaccg tgaaatctca agctgttcaa acacagaaga tttccaagcc cgtcgtgccc
    36181 aaatccgtta ccgtgatgaa gcagatggca aggtgaaact ccttcatacc ttgaacggtt
    36241 ctggacttgc agttggacgt acagtggctg caattcttga aaattaccaa aatgaagatg
    36301 gttctgtgac catcccagaa gcacttcgtc catacatggg tggagctgaa gtcatcaaac
    36361 cataaaaaat aaggtttagc tatttctagc tagacctttt ttcgtaacca aatcagataa
    36421 gcacctagta caaagaataa aatagttagg catataacgg tttcagccaa taccaggtaa
    36481 tccagaaatg gaagtttcaa aattccctga gccatcttga gcgaggtcgc tgtgataatg
    36541 gttgggaagg tgagggctga gaaggctggt tgaaaacctt gttttaaaat gttgggcaga
    36601 cgagttaaaa caaagaaaaa gaaggattga gaagccaaaa tcatgacaat caagacccaa
    36661 gtcggcaggc tggttcctcc tactcgaact agagaagcca agagtagaga gaaaggagca
    36721 cagtagattc cttcttgtcc aagcaaggct agtgggagtg gatatttctt taaatcgcta
    36781 taaataaggg gatagagata gaaggtcaag agaaaaccaa aactcaaggt cgcataggca
    36841 atttcgataa tacctaccag aggataggtc aaggcagcca ctgctatccc cacatagaga
    36901 accgtccaac ttggagtggc atgaaccctc cgccctggac aagcaaactt gatggtaaaa
    36961 ccagcaatca aggtcaaatc caagagaaat gaaaaccacc aaatcccttg tgctaccaaa
    37021 ggaagataag agaatacgcg aaagacatag gtcgataaaa tcatcccagc cataggaaag
    37081 gttgccattc ctgacaaaag agggggcttg gtcaattctt gcttggtttc tttccaatta
    37141 aagagatgca gaattagaaa gtaaatccat aaaaccaaac cagtcagact aaaaagatgg
    37201 gatagaaccg gcaacgtatc taaaataaga tttccagctc ctgccaaacc tagcaaacaa
    37261 cctgaaaata ctaaggggag ttttttcatc ctaacctcca ataatcatgt tagtttcagt
    37321 ataacataaa agcgcttaaa tgaggattta aaaaacgaag tccgcttatt tcagacttca
    37381 ttttactcag atatgaatta ggcataaggt tgcaattctg gattaattgg tgtattagct
    37441 aagttgttgg catagttaca gaggattgct aggctgacac caaaaaccac atccaaggca
    37501 ttttgttgag tgtagccagc ttctaaaaac tcagacaagg cttcatctcc tacacgaccc
    37561 ttggtattga taactgccaa ggtaaactta gctagggtat ccaatttagg atctgtttca
    37621 attggagtac gattgcgaag agcttgaatc aagtcatcat tcatctggat ttgtttgatg
    37681 gaaaaggctg tgtgacctgc gacacagaag gcacaaccat tggtcacggc tgccgtgatt
    37741 tgcaccactt cacgctcaac gggtgtcagg ctgttgcgac ggtggataga tgagacaatt
    37801 tgataggctt ctaaaacagt cggggcattg gccaagagac cgattaggtt gggaatatag
    37861 ccattgttgt ctttttctac tgtttcaaga atttctttca cttctgctgg tgctgactct
    37921 actgtatgga tagtaaatgt tgtcataaga tacctctttt cttattattg acactaatat
    37981 tattggaaaa tcttataaaa tcctgattcc taagtttatc taagataaag ctttattctc
    38041 tcataagatt ttcgttgtta tattagttta tcacacttcc aatcacttgc ataatatata
    38101 ttatatatca ggctgataaa aattatttat aggcaaaaaa atcacacgag ctgtgtgatt
    38161 ccattatttg tcaaaatact ttttagtttc agcaataacg actggcgaca agaccaagag
    38221 ggcaatcaag tttggcagag ccatcaaggc gttaacgata tctgcgataa tccagaccat
    38281 atccaactcg ataaatcctc ctaacaagac catgagcaca aaaaacacac ggtagagcca
    38341 gataaagcga gccccaaaga ggaactcaaa acagcgttct ccgtaatagt tccaacctag
    38401 aatcgttgta aaggtaaaaa gtacaaggaa gatggtcaag agggcaggcc caaagtgtga
    38461 aaagactgtt gagaaagctg actgagtcaa ggcaacccca ttcaagtcac cactccaaac
    38521 tccagttacc aagatggtca aaccagttag agtacaaatg atgagggtat caataaaggt
    38581 tcctgtcatg gaaatcaaac cttgctctac tggttcattt gtcttggcag ctgcagctgc
    38641 aataggagca gaacccagac cagattcgtt tgagaacaca ccacgcgcca caccattttg
    38701 aatagccatc cgaacgctag caccagcaaa tccacctacc gcagcaaggg gactaaaagc
    38761 tgaggtaaag actaaagcga ttgtgccagg gatttttccg atattaaaga aaataactgt
    38821 aagagttcct aagatataaa tgagggccat aaaaggaaca acagtagttg aaaccttaga
    38881 aatagacttg agtccaccaa agactgcaat cgctacaaag acagacaaga cgagagctgt
    38941 gatggctggc gaaatcgtcg ttgtattttg gatagattct gtaatcgagt tgacttgggt
    39001 gaaggttccg attcccaaga gagcaaccaa tactcctgct actgcaaaca aaacagcaag
    39061 tggtcgccac ttttctccca tccctagaag gatatagtgc atgggacctc ccgctactgc
    39121 accatggtcg tccttggtgc ggtatttgat ggccaagagt ccttccgcat acttggtagc
    39181 cattccaaag aaagccgcca tccacatcca aaatagagct cctggtccac caaccttgat
    39241 agccgtcgca actcctatga tatttcctgt tccaacagtt gatgccaagg ctgtacacag
    39301 agctgcaaaa ctggatacat caccatgtcc cttatcctgg ataaaaataa gctgaaaggc
    39361 cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg gttaggtaaa tccctgttcc
    39421 gaccaataaa atcaagaggg gcggtcccca agcaaaagca tcgattgatt taagcaattc
    39481 taacatttcc ttctcctatc gtttcaaccc caaaagaaag agcacatgca agatacatgt
    39541 actctggaat gcttagataa atgctaaaaa gcggtctatc ctagctctgt ccttttacct
    39601 gagagtttga gcagttgcct gccttgcccc ttcggtgcct ttacggtctc tccagagttc
    39661 cgtccattta cagtcatgga aaatcaaacg attccccact tctattaaac ttcattcggt
    39721 gttggtattt aattgattct aattttacaa aaaatgttgg cttttgtcaa tgtgtttatt
    39781 agtaaaaatt agttcaacag tttttacttt ataaagtcca gaatactgct atcctttaaa
    39841 agtgacaata gtcgcaccac tgcctccagc attttgtggg gcatagccga aactcttgac
    39901 atgtttgttt ctttgcaagt atttggtaac tccttcacgg atgactcctg ttccgatacc
    39961 atggatgata tcaacttgag ccatattgtt aagcaaggct tggtcgatga aggtatctag
    40021 ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc agtctagctt gaggtcctcg
    40081 cccagaagtt cgtttcacaa cattgacctg tttcttcttg actggttttt cttgctgggc
    40141 ttgaacaaga tcaaactctt tctcttccaa ggtcatctta atcaagccaa cttgggcttc
    40201 ccagcggccg tccttaagtt gactggtcaa ggtaccacgc tgaccataac tgagaaccac
    40261 gatatcatct cccacctttg gagctcgttt tttcttggcc ttttgaagga ccttgttttt
    40321 agacaagtcc actttttcag gagccaattt tttcaacttg gctttggctt caatgatttc
    40381 gtggggcttg agttgggatt tactgtggag atttttgaga atctggtcac tttcacttag
    40441 ggccatatcc acaatctcag cagcctgttc acgcgccttg ttaagctcgg tttccttttc
    40501 acgattaagc tcgttgtaga gtttttttag cacacggttc atcttgagat tttcttgctc
    40561 cacctcacgg atattgtcca agcgtttgcg gctttccagc gtctgctctt ctagttgctc
    40621 aatgatacga ttgacgtcat tgtcctgatc gatctgctga ctggcatctc ctacgataac
    40681 ttcagatagg cctagacgtt tggcaatttc aaaggcatta cttcggccag gaacaccctg
    40741 cataaagcga taggtcgggc gaagagttgc agtatcaaac tccatactgg cattttgcac
    40801 aaaggctgtc tcaataccgt aggccttgag ttctggatag tgggtcgtcg ccatggtctt
    40861 gatttgacgc aggcgaaggt cctccagaat agccatggca agggctgctc cctcttgggg
    40921 atcagtacca gcccccaact catccaaaag taagagtgaa tgttggttga ccttgccaag
    40981 aatatccacg atattggtca tatggctaga gaaggtagac aagctctgct caatagactg
    41041 ctcatctcca atatcagcaa agatttcttc aaaaatacca acacgacttc ccttgtctgc
    41101 taaaatcggc aatcctgact gggccatgac ctgtgtcaag cccagagttt tgagcatgat
    41161 ggtcttccca cctgtattgg gacctgtaat gacaatagct gttaaatctt gaccaaaata
    41221 gacatcattt gcgacggcat ttttgaccaa aggatggcag acatggagca gttgaatctc
    41281 ttgattttct gacagctgag gcacgactgc ttgtctttct tggataaatc gaaccttggc
    41341 acgaatcaag tccagatgac cgataatcca agcgtcatta gcaatctcag ccgcatgagg
    41401 gcggacacgc tcagaaattt cttggagaat gcgaagcatt tcatagcgct catctgctcg
    41461 cagactagca atttcttcgc tcagtttgac tacctcacgt ggttcgatat agacggtgtt
    41521 tccactagca gaaatatcat gaacgacacc tgcaatctta ttgcggtagg tgtttttgac
    41581 tggtaaaacc tgacggccat ttctgctagc aacaattcct tccgtcaaca tctgcgcttt
    41641 ttgcttgagc aagtcttgta aaacatcgcg tacctgactc tcgctatcat gtatttttcg
    41701 acggattcgc gccaattctt cactggcaaa attttcaatg aaacccgcat cattaaaggc
    41761 ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc tcaaaccaaa gggctaattc
    41821 ttccaagctg acattttcca gattggcgta aaaactttga agttctcggc tggtaagaag
    41881 cacgcgtttc aagagtagga actcctcgat attgagatcc gctcccatct ccaacctctt
    41941 gcagactcct gcaatttcct tagttgagag aatagtaaaa tgcggttgct cgacgaaaag
    42001 agcctgcatt tctttcatct cagcaaaagc ctgtttgatt ttatctgctt tggcagtcgg
    42061 agccagctgt ctcaattgct ccaagccctg ctcggtcaac aaatgaggct caaacaaggc
    42121 cttgatctta tcgaactcta atgtttctaa tattttctta ttcatcttta tttccttgtc
    42181 tttgaatgtc taggtgtggt agctttttac attctgatag attcgagtca aatctgtaaa
    42241 caaagggcta ggaaaactcc tgcccttttt atccgattaa atttgtcacc cagatttgtt
    42301 tgagccaact ggttgttatc ggtatgctct ggatgatgtg ttttgcgacg atactctttt
    42361 caagaggatt ttgtataact gccatgggga tggtcgccaa gattgtcaag gccatttgca
    42421 agacaaataa ggtcaccaac atggacaaga tacctgctga aacttggaac aacttaccac
    42481 ccagtttttt gctaggaatc aagtgtaaga gaagaccaag caaacgacca atgctataga
    42541 caatcccaaa tacaagcaag tagccgatac ctgcataaaa gaccttatcc agctgaaaga
    42601 gttgatccga tgggaaaaag aaagtcccct gaccttcctg cgaatttgca taagggagca
    42661 ataaatggaa ttgctctcca agccccttat aaaactggcc agccataaaa gccgatgcca
    42721 tggctgaaat caggtaataa acctgtaaga gcaggcctct ccgatagccg atataaaatc
    42781 cccaaaccaa gaccaataga agaaggaatg aaatcataag gaatcctcaa tcttgctctg
    42841 ttcttgctta caagtcacaa gcttgtgacg gagttcttct agctcttgct ccttatcgtc
    42901 aaattcaatc tcacggctga gctgagttga taaacagttg actgccaaca aaagagcgat
    42961 tgtttcatca tctgcgctag gcatttgttc tttaattgct tggtattttt ctgtcgcaac
    43021 cttagcgatt tcctccataa aaaggttatc atgttcgctt gtcaaggtta acgatttttt
    43081 cccgaatgta aatttgaatc gatttagatt tgccataaaa ttcacctcac gatattatac
    43141 caaaattcgc taattttgtc agtttttaca aattttactg cttttgtggt acaatagaaa
    43201 ctatggcaag tatcacactc acaccaagcg aaaaggatat tcaggctttt cttgaacact
    43261 atcaaaccag tctggctcct agcaagaatc cctatatccg ctactttttg aaactacctc
    43321 aagcaacggt ttctatctat acttctggaa aaatcttgct tcagggtgaa ggggctgaaa
    43381 aatacgccag tttctttggc tatcaagctg tagagcaaac cagcggacaa aatcttcctt
    43441 taattgggac agatgaggtg ggaaatggtt cctactttgg tgggcttgca gttgtggcta
    43501 cctttgtcac acctgaccag cacgactttt tacgaaaact cggtgtgggg gattctaaga
    43561 ctctgaccga ccaaaagatc cgtcagatta ctcctattct caaggaaaaa attcagcacc
    43621 aggcactcct tctctcaccc agcaagtaca acgaggtcat cggagaccgc tacaacgctg
    43681 tttcggttaa ggttgccctc cataatcagg ctatctatct cctccttcaa aaaggtgttc
    43741 agcctgagaa aattgtgatt gatgccttta ccagtgctaa aaattatgac aagtacttgg
    43801 cacaagaggc caatcgtttc agcaatccta tcagcttaga agaaaaggct gagggcaaat
    43861 acttgtctgt cgcagtttct tctgtcattg cgcgtgatct ctttctggaa aatcttgaaa
    43921 atttgggacg agaactgggt tatcagctcc caagtggagc tggaacggct tctgacaagg
    43981 tggctagcca gattttgcaa gcctatggta tgcagggact cagcttctgc gccaaattgc
    44041 actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag gtaagttatg aattcattta
    44101 aaaatttctt aaaagagtgg ggattgttcc tcctaattct gtcattacta gctttaagtc
    44161 gtatcttttt ttggagcaat gttcgcgtag aaggacattc catggatccg accctagcgg
    44221 atggcgaaat tctcttcgtt gtaaagcacc tccctattga ccgttttgat atcgtggtgg
    44281 cccatgagga agatggcaat aaggacatcg tcaaacgcgt gattggaatg cctggcgaca
    44341 ccattcgtta cgaaaatgat aaactctaca tcaatgacaa agaaacggac gagccttatc
    44401 tagcagacta tatcaaacgc ttcaaggatg acaaactcca aagcacttac tcaggcaagg
    44461 gctttgaagg aaataaagga actttcttta gaagtatcgc tcaaaaagcc caagccttca
    44521 cagttgatgt caactacaac accaacttta gctttactgt tccagaagga gaataccttc
    44581 tcctcggaga tgaccgcttg gtttcgagcg acagccgcca cgtaggtacc ttcaaagcaa
    44641 aagatatcac aggggaagct aaattccgct tctggccaat cacccgtatc ggaacatttt
    44701 aagaaaccta agaggccgag aatcaccaat ctcagcctct tcttctatcg tgagaaaatg
    44761 attggtaact atctaaactt accagaacag aaacacctca actctcacct attcatgcaa
    44821 aggaatttta tggaagttta tttttcagga actattgaac ggattatttt tgaaaatccc
    44881 agcaattttt atcgcatcct cctcctagaa atcgacgata cggacgcaga ggattttgat
    44941 gattttgaaa tcattgtcac aggaaccatg gctgatgtaa ttgagggcga agactatact
    45001 ttttgggggc aaattgtcca gcactccaag tatggagaac aactgcaaat cagtcgttat
    45061 gatcgcgcaa aaccaactag taagggcttg gtcaagtact tttcaagtag ccatttcaag
    45121 gggattggtc tcaagacagc tcagaaaatc gtggatacct atggcgaaaa taccattgac
    45181 gaaattttgc aacacccaga aaagttagaa ggcatcgcag gactctctgc caaaaatcgc
    45241 gaggctttcg tctccactct ccgtctcaac tacggaacag agatggtttt ggccaaacta
    45301 gccaactacg gcattcccaa caaactagcc tttcagattc aagactttta caaggaagaa
    45361 acccttgatg tggttgaaaa ttatccctac cagctggttg aggatatcaa gggtttgggc
    45421 tttaccattg ctgaccaact agctgaggaa ctaggcatcg aaagtcaggc tcctgaacgc
    45481 ttccgcgccg gtctagttca cagtcttttt caggcctgta tggaaacagg agacacctat
    45541 gttgaagcac gggatttgct ggaacaaacc cttactctcc ttgagtcttc ccgtcccgtg
    45601 gaactagacc ccagccaagt tgcccaagag ctctcctacc tgatcgaaga agacaaggtt
    45661 cagcagattg ataccaagat ctttgacaac agcctctttt tcgctgagga aggtatccgc
    45721 agtcacttga ttcgtatcct tgaaaaagga aaacagaaga gccaagattt agaaactatt
    45781 caaaagcata tcactactgt cgagcaagaa ctggggattg agtatgataa cattcaaaaa
    45841 caagctattt gtgacgctat ccagaacaag gtctttatcc tgacaggtgg acctggtact
    45901 ggtaagacaa ctgttatcaa tggaatcatc gctgtttacg ccctgttaga gggacttgac
    45961 ctcaggaaga aaagcaacct gcccattctt cttgctgctc caactggtcg agctgctcgt
    46021 cgcatgaatg aattgacagg tttgcctagc gcgaccatac atcgccactt gggaatgaca
    46081 ggtgacgatg ataccagtca tctggaagat tacctagatg ctgactttat catcgtggat
    46141 gaattctcta tggtagatac ttggctggcc aatcaactct tctccaatat ctcttctaac
    46201 agtaagatcc tcatcgtagg tgacagtgat cagctacctt ctgtcagtcc tggacaggtt
    46261 ctagcggatc tgcttcatat tcctttgatt cctcagactc gcttggaaaa aatttatcga
    46321 caaagcaaag aatcaaccat cgtcacccta gctagtcaga ttcgacaggg catcttgcca
    46381 gctgatttca cccaaaaaaa agctgaccgt tcctactttg aaattgctag tggccatatt
    46441 cctgccacca ttgaaaaaat cttaggtgcc gccctcagaa atggtattcc tgcccgtgat
    46501 atccaagttc tggctcctat gtaccgaggg acggcaggga ttgatgctat caatcagctc
    46561 atgcaagacc tgctcaatcc cccacaaaaa gatcaactca gttttgaagt tcctcagtgc
    46621 cactatcgta agagagacaa ggtcattcat ttggttaacg atgctgaaat caatgtcttt
    46681 aatggagatt taggagctat cacagacctg attcctggta aatacaccga atcgaaacaa
    46741 gacgagattg tcattgattt tgatggtaat gaagtctctt acccccgtaa cgaatggtac
    46801 aagattcgct tggcctatgc catgagtatt cataagtctc agggaagtga gttcccagtt
    46861 gtcatcctac cgattactag tgctagccga cgtatgctgg agcgaaatct catctacaca
    46921 gccattacac gtgccaaaag caaactcatc ttactaggcg aattacaagc cttcgactat
    46981 gctacccaac acatcggaac tgcccgaaaa acctatctga ttgaacgctt cagtgatcta
    47041 ctggagaatg ttgaagaaaa gcaacaagct gtctctgaaa cagtcacatc aagtgcctct
    47101 gaacaatcct acatcctaac cgaagaaaac tgggacagca ttccagccat gattgggatt
    47161 acagacacag acctcaaaga gatttttgga aaatagtaca tcagaaaacc caccaattca
    47221 ggtgggtttt ctgtttatta agattatttt actgttgctg tgcttgtgat caattcaaca
    47281 gcttttttga tagtgatatc atgtttcaac atgtcagctg aaagcaagtt ttgaacttgt
    47341 gcaacttcca tgttgtagtc tgctgccaat tgctcaactt ctttttggat ttcttcttct
    47401 gaagcatcaa atccttcagc tttggcaact gcttcgataa caaggttagt cttagtacgt
    47461 gactcagctt ctgcttggta ttggttgtga aggtcttctt gagtagttcc agtgatttgg
    47521 aagtacatgt cagggttgat cccttgacgt tgcaagttcc caaggaattc atttactgaa
    47581 cggtgaactt cttcatggat catttcttct ggaagttcta cgatttcagc gttttctaca
    47641 gctgtatcaa ttgctgcacc ttcaactgca tctttgtaag cttcttcttt agcagtagcc
    47701 aattctttgc ggtatttttc tttcaagtca gcaagtgttt caacttcttc atcaatgtct
    47761 tttgcaagtt catcgtcaag agctggaact tctttagctt ttacttcgtg gatagttgtc
    47821 acgaatttag cttctttacc tgcaaggtct tctgcttggt agtcttctgg gaatgttacg
    47881 ataacatcaa cggtttcgcc agctgagtga cctaccaatt ggtcttcgaa accagggatg
    47941 aattgacctg aaccaagtcc aagtgagaag ttttcacctt ttccaccgtc aaattcaaca
    48001 ccgtcgatag aaccaacgaa gtcgatcaca acagtgtcgc cgttttcagc agcagcttcc
    48061 ttgataacca attcagccag attgttgcgt tcgcgttcga tacgctcttc aacatcagcg
    48121 tcagttactt ctttttctac atcaactgat acttcaaggt ttttgtagtc acccaatttt
    48181 acttcaggtt ttgtaacgac ttcagcagtg ataacccagt cttgaccttt ttccattgaa
    48241 gttacgtcaa tttttggttg ggcaaccact tcaagaccag cttcttttac agctgcttca
    48301 taagcgtttg gcaaaagagc gttcataacg tcttggtaaa gtgattcttc accaaatttt
    48361 ttatcgaaga taggacgtgg aaggtgacct ttacggaaac ctggaacatt aagagatttc
    48421 ttcactgact tgaagacacg gtccaattct ggtttgattt ggtcttgaga gatagtgaaa
    48481 gtcaagacac cacggtttgt ttctttgttt tcaaatgata cagacattct gtcatttctc
    48541 cttaaaattt tttaaataca gtctattata acattttcta taaataaaat ctagactaat
    48601 gcagacaatt atagacaaca agcctttttc ctaactaaaa cactcataaa gtatagacaa
    48661 ttttagacta ctttggatat cttttggtta gtcattttcc aaaactaatt tatctaattt
    48721 atctaatttt tcagttatat aatagattga aactagaata gtacacctct acttctaaaa
    48781 catttttaga aatcgatttg actatcctga tcgatttgtc ctgttcttgt ttcatttcac
    48841 tatatagatc gcattcgaaa gaattcgttc caaaattgct tggttcgttc ttctcttgga
    48901 cgactaaaga attgatgggc attatttttt tcaacaattt tcccactgtc cataaaaata
    48961 acatgatggg ctacatctct agcaaaaact atctcataaa gctgatcaaa aactcaatct
    49021 gaggagaaaa tccaataagg ctttccataa taaaggacat cctatcaaga tttttgaaca
    49081 cccgataggc tgcctttttc cgattttgaa gactttttgt ccagcttctt ttaccttata
    49141 aataacaaca aaaatcaaag acaagctaga aagattaccg cagataactc aaacagtgtt
    49201 ttgaggttgc agataagact gacggagtca gctcaaagca ctgctttgag gttgtagata
    49261 gaactgacga agtcagtaac atatgcctaa gacaaagcga tgctaacctg atttgaagag
    49321 attttcgaaa aatattaaat atactctaca atttgatcaa tcaattcttg gtcgtctaaa
    49381 cctgtaactt gtataacaac atctttgact gattgtttag ccaacaattc acctaatcga
    49441 atactttctt catcatttac atcgcgatag tcaaaggcat agccaactgt tttaagtagg
    49501 tttttatatg acaaactgag ttctttcaat tcacgtatcg gccggatgaa tcgttcatta
    49561 tagcctaatt ttcggattgg agtacgagct acgcgactaa cctcgtccac tatgaaaggg
    49621 ttttcaaacc gttctataat gactttgtga taattctcca attctttttt atcaaagttc
    49681 catttggcaa tcaagagact ccgaatttca gctaatacag attcaatccg agatttaata
    49741 ttaggatttt gaagagcttc caaaattgtc ttggcaccat aatgcgcacc aatgtaagct
    49801 gaagttgcat gtccagaatt gactgaaaaa agttttcgct caataaaggg ttctaaatct
    49861 tcttcataat gcacatcttt tagacgtaaa tctggatttt taagacgctt ggtttccacg
    49921 acccattcat taaagggctc gaccacaaca aaaagggaat cttcgtgact ttgtgctgga
    49981 acaatcctgt ctactgcagc atttggaaaa cctatgtagt tatcagcaaa tgtcaaacct
    50041 tccggactta aatatttctt gacttcttga taaagaaatt gagacccgcc aatcatattt
    50101 tcacaggcca taacatccaa tgcctgtgta tttcctgcaa ctcggcgagc ttcgattcct
    50161 ttggctagaa gttcggcgat aaaagggagt atattaggtc cgattgcagt agtaataata
    50221 tccgtccttt gaatcgcttc aatgacttgc tcaggatgtt ctttgctatt aatgccagcc
    50281 acattagtta cttctatacg agactgtcct ttctgtgcaa tttcaatttc atacttgccc
    50341 ttttcattta gagcatgaat tatctgatta ttgacatcca caaaatcaat atggaaacca
    50401 tttttaaata gaatttcacc tataaaacca cgaccgatat taccggcacc aaaatgaaca
    50461 gaatgtttca ttcaatttct ccttttccta tttgagggac atatatacta gatgacaaat
    50521 gacgaaattc aattattcaa cagcatcaaa taagcgcaat acttcctctt ttgactgagc
    50581 atctgctagt ttaagaacat tatctacatc tgcacagaag acagaaattt tctgaataat
    50641 ttctaagtgt tcattaccaa taccagcaat accaaaaaga accgttgcca cttgagggtt
    50701 agatacattc ccaaaatcaa cccctctagg gacttgaacg actgtaatac cagacttgag
    50761 gacatccttt tttgctgcat ctgttccatg cggtatggcg ataaagttac ccatgtaaac
    50821 agataactct ttatctcgct caatcatggc ttcaatatag tcttcattaa catatccacc
    50881 ctcataaaga acttgcccac aataacaaat agcttcctcc ttgttagaaa attgtttatt
    50941 aagcttaatc aaatgttttt caagtttcat attagttctc caatttctta attttttcgt
    51001 taaaaatagt atttagcatc tgataaataa tggattgatt tcccgtcttg taaatctctg
    51061 tataaagatg attttcaata atcgactgac taatagctgt cattaaatct ctagcttcct
    51121 cgctagcttc tttagacatt agcattagca gacacctttt gacctcttct tcctctcgtt
    51181 tcattgacaa tgcggagata ggtagtttga gttcaaacat agtaaaacta tttgttgtta
    51241 ctttgctaga ctgactatgt aaaagcacca gaccagtatt aggaatagcc ataggactat
    51301 tctggaagtg agataacaat tttcttgtta ggtaatctct gtcactcaca ttcttctgat
    51361 attggatgat ttgttctacc gtgtgctcaa atgattgatt attctccaat tgaaccaact
    51421 cgaattgact caaaagctga ctactagata ttaaataatc ttgcaagtca taacttttct
    51481 ctggagcgat agcatcacgc gcgacaattg tacgatgtgc ctgtacatac tgaagtcgtt
    51541 cctgtaattc aagcaattct ttgacggttg gaaaactaga aattacatcg atttcctgat
    51601 tagtcagcgg cttggtagat aaaatataat catactgact gagatcaata ctgtggtaat
    51661 ctactagaga ctgaatatct atcaactcta caaaaggagc aacactctta attttactga
    51721 ctaataaatc tctagtgacc cgacgttcat ccgttaaaag caaaacacgg actggataaa
    51781 tctctggact acggcctaag ctagagataa aatgtagggc aatcatgcca tactcatact
    51841 ctgtatgaag atatttcgga aaaatatcat tcactaaaag actgatgact gtataaagaa
    51901 atttattcct ttcaactaaa atctggacag attctggcaa attttcaccc tgaaaaagga
    51961 tagggacgcc taaactgagc cgaatatgat ggaaaagaaa attgaataaa accttgtcct
    52021 taaaaaagtc aattttgata tacatggaaa ccgtatcaat cagatttgaa atattgtaga
    52081 aaaattcacc atcaaatttc tccgtaaaga gcggattgtc ctgacgttta atgattaatt
    52141 catccaagat gctcgcaaaa tagataattt cctgaatact ataaaattgt gcagtctgct
    52201 tagagtaagc ttgaaaaatt ttttgagaaa tttccaaagc ctgcttacta gtattaggtg
    52261 aattttcaat gttttgctcc tgacctataa gagataacaa gattgcaaaa aacatcttca
    52321 tcctagcatc catatctgga aaacctgaca gttgcttatt aacaatctga ctggccagcc
    52381 tagttctatc tgcttctaaa atatcaaagc tcccaaaatt accggttgaa aaatctgcta
    52441 ctgagataca gtttgtcagt aaaatagcca aaaatcttct cttaccaact gaatcaccag
    52501 aaatccgata acctttttgt cgttcaattt tcagatcaaa gtctaaaaga cgcttatcaa
    52561 tatctgaaat atcctgaata atagttacat tactgacttt cgtgcactct tgcaatgctt
    52621 cattggtgac aaaaccgctc tcagtcagaa ggcgataggt aatcaactct tgtctttctt
    52681 ggggactata ctcaactaac acttcaagtt ctgtcggcaa atcatccaac tctccagtca
    52741 aaatatagta tttcccatgc ttcgttattt cgattccata ttgctccatg ctatctgtca
    52801 aatctgataa agttcgataa attgttctag atgaaacctg taagatttca gtcatatctt
    52861 gcattgaaag cttccctaca tgtaggaaag ccttcaataa ttgttcttct cgtttggtta
    52921 atagcattcg taatttagaa acctctagtt ctatttgtac attctagcag ccattttgtc
    52981 atattctggt gttgttacta aactatccac aataagaaat tgagaattcg gtgctgcttg
    53041 ctgcacttct gcctgtaaag aaatagttgt tacaatcatt atatttttag aattaaattc
    53101 acctaattct gaaattttgg cagtagaaac tggaatacga atattcttgt ttctaaagat
    53161 agcccgaatc gtttcacagc ccatagttgc agttccctgt gctttaccat aagcaactac
    53221 tacagcatca atagggttaa ggtcaatttg ctgactatct actggtgctg aagttggtat
    53281 atctccttca atttctgcta ttggagaagc tcctgttaat gaagctacac tttcatcata
    53341 acgaggggac gctaagaaat tatcaacaga aacatgaata gcacttggac tcttgtcttt
    53401 agctcttggt gtcagttctt cctgagtaac aattaatgtt tttggtgtat caagcaaatt
    53461 tgagattgcc tgattagata ctggaatctc tagacctgct tttttaacct tatctcgaag
    53521 aatactagct cccatagcag agcttcccat accagcatcg caggcgaaaa tgattttttc
    53581 cactgagtct gtcgaaacaa ctgcatcaac agaagttgat actaactgac ctttagactg
    53641 agccttagct gcttgggtag ccgcctgagc agcttcgagc gaatcctcag ttgacttgtc
    53701 tgcatgaaga ataagggctg ctacaaggaa agaaacaact gctgctacta aaacacctag
    53761 aagaacattt atatggggcc aaacaccttt tggcgccgta gccataatcg caataataga
    53821 acctggtgaa gctggagatt taagaccagc gtctaagagt tgaaaagtaa aagttccaga
    53881 gatacctccc gccatagcag ctaaaaatag agtaggcttc atcataacat aaggaaagta
    53941 aatttcatga atccctccga agaaatgaat aaccattgcc ccccaagaag aagatttagc
    54001 agaaccttta ccgaatacag cataagctaa tagaattccc aggcctggtc caggattagc
    54061 ttccaatagg aagagaattg acttaccagc ttgagctacc tgttctactc ccagaggagt
    54121 aaaaatgcca tgattgaggg cattattgag gaaaaggact ttagccggtt cgatgataat
    54181 attagccata ggaaggaggc gagcattgac aatagcctca acaccattcc caacagctcc
    54241 agtaagagtc gatacgactg gaccgattgc atagaaagcc aaaagcaata atgcaaaacc
    54301 aacgagatca gctgagaagt tattaactaa catttcaaat ccgggacgaa ttttttcttg
    54361 gaacttctca tcaaatttct tgatagtcca tcctcccagt gggcccatta ccatagctcc
    54421 gataaacata ggaacactag aacctgtgat tgcaccaaca gtagcaatag atcctacaac
    54481 ggcaccacgt tggccatgga tcatatatcc acctgtgtaa ccaatcagga ttggcaataa
    54541 atacgttaac ataggaccaa caacagtagc taactgttca tttggcagat aaccatcagc
    54601 gataaagagg gcagtcaata ctccacaagc aataaatact ccaatattgg gcataaccat
    54661 atttgaaagc gatgtcccta gtttttgaac cctgactttc aatgatactt tttcttccat
    54721 tagatcatcc tccttttctt aaaactagta tatacaaagt taaaaacctt taaaactaaa
    54781 gttttgtcac agattttgtg tcaaaacatt acttttgatg aggctgggca aaaaggctta
    54841 aaaattataa aacgcatcat atcaggtgta catgaactac accccaaaag ttagacagaa
    54901 aaaatctaac ttttggggtg t
//
LOCUS       DAVHSL010000008        49919 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000008 DAVHSL010000000
VERSION     DAVHSL010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.008"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(151..861)
                     /gene="treR"
                     /locus_tag="VVR39_000476"
     CDS             complement(151..861)
                     /gene="treR"
                     /locus_tag="VVR39_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU6030019.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            1046..3013
                     /gene="treP"
                     /locus_tag="VVR39_000477"
     CDS             1046..3013
                     /gene="treP"
                     /locus_tag="VVR39_000477"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU6030020.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            3191..4816
                     /gene="treC"
                     /locus_tag="VVR39_000478"
     CDS             3191..4816
                     /gene="treC"
                     /locus_tag="VVR39_000478"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU6030021.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            5072..5320
                     /locus_tag="VVR39_000479"
     CDS             5072..5320
                     /locus_tag="VVR39_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU6030022.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            5527..6321
                     /gene="racE"
                     /locus_tag="VVR39_000480"
     CDS             5527..6321
                     /gene="racE"
                     /locus_tag="VVR39_000480"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU6030023.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            6318..7289
                     /locus_tag="VVR39_000481"
     CDS             6318..7289
                     /locus_tag="VVR39_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU6030024.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            7265..7786
                     /locus_tag="VVR39_000482"
     CDS             7265..7786
                     /locus_tag="VVR39_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU6030025.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            7783..8244
                     /locus_tag="VVR39_000483"
     CDS             7783..8244
                     /locus_tag="VVR39_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6030026.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            8235..8975
                     /gene="xerD"
                     /locus_tag="VVR39_000484"
     CDS             8235..8975
                     /gene="xerD"
                     /locus_tag="VVR39_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU6030027.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            8975..9703
                     /locus_tag="VVR39_000485"
     CDS             8975..9703
                     /locus_tag="VVR39_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU6030028.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            9722..10291
                     /locus_tag="VVR39_000486"
     CDS             9722..10291
                     /locus_tag="VVR39_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU6030029.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            10278..11000
                     /locus_tag="VVR39_000487"
     CDS             10278..11000
                     /locus_tag="VVR39_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6030030.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            11000..11242
                     /gene="yidD"
                     /locus_tag="VVR39_000488"
     CDS             11000..11242
                     /gene="yidD"
                     /locus_tag="VVR39_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU6030031.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(11467..12432)
                     /locus_tag="VVR39_000489"
     CDS             complement(11467..12432)
                     /locus_tag="VVR39_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6030032.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(12528..13280)
                     /locus_tag="VVR39_000490"
     CDS             complement(12528..13280)
                     /locus_tag="VVR39_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6030033.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(13277..14233)
                     /locus_tag="VVR39_000491"
     CDS             complement(13277..14233)
                     /locus_tag="VVR39_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU6030034.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFVLLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFILANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(14223..15182)
                     /locus_tag="VVR39_000492"
     CDS             complement(14223..15182)
                     /locus_tag="VVR39_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030035.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTHKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(15605..16306)
                     /gene="galE"
                     /locus_tag="VVR39_000493"
     CDS             complement(15605..16306)
                     /gene="galE"
                     /locus_tag="VVR39_000493"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6030036.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRATVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            16707..17771
                     /gene="pepA"
                     /locus_tag="VVR39_000494"
     CDS             16707..17771
                     /gene="pepA"
                     /locus_tag="VVR39_000494"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU6030037.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            17793..18089
                     /locus_tag="VVR39_000495"
     CDS             17793..18089
                     /locus_tag="VVR39_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6030038.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            18771..19214
                     /locus_tag="VVR39_000496"
     CDS             18771..19214
                     /locus_tag="VVR39_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6030039.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDLEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            19218..19982
                     /locus_tag="VVR39_000497"
     CDS             19218..19982
                     /locus_tag="VVR39_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU6030040.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPESQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            19997..20725
                     /locus_tag="VVR39_000498"
     CDS             19997..20725
                     /locus_tag="VVR39_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030041.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            20718..22238
                     /locus_tag="VVR39_000499"
     CDS             20718..22238
                     /locus_tag="VVR39_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU6030042.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKPAEQVAKEFLQEQGLLKK"
     gene            22408..23273
                     /locus_tag="VVR39_000500"
                     /pseudo
     CDS             22408..23273
                     /locus_tag="VVR39_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23302..24294)
                     /locus_tag="VVR39_000501"
     CDS             complement(23302..24294)
                     /locus_tag="VVR39_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HEU6030043.1"
                     /translation="MILIVTLNPSIELLYFEKNFTLGAHNRFQNSTIMAAGKGINCAR
                     ALSYLGINATALTLVGGKSGEFFKQHLAQEKFHPLYIPIDGETRHSITIMHNDNIHTE
                     IVEAGPKVDQGLKSQIFDTLLQVIKEKNISIVSLNGSVHSDDRDFYNDLIQFLRENTD
                     STLKILADFSQTALQKIVNDAIHLPDFIKPNMEEFCQLTGLSVTTKQEILDYLMDKPS
                     PIPYTLVSCGEQGAIAQFNGKLYDVTAPSINLVNPTGSGDSTVAGAIYAFEQNLSDED
                     IIRYATASGTANAMENGVGVARKEIVEKLIPQVIIKEIHKSWSLGQNSSRPQKS"
     gene            complement(24311..25051)
                     /locus_tag="VVR39_000502"
     CDS             complement(24311..25051)
                     /locus_tag="VVR39_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6030044.1"
                     /translation="MKINRKKEILNLLENSDVISYQELAQSLHVSTMTIRRDVSELEK
                     ENLVIKEHGGVRKVTFNTKTTDEKRLLYPEEKDYIAQLAANLIEPNSVIYLSAGTTIL
                     ALAKHLKNQHKHIITNSLFTFNWLNEHNFENILLTGGEFVSKTEEFHGEHAERLVKDF
                     LIDYAFLATNGLVDDHLTAFSSFGGRLQSIAMNQSRKVYLLADHSKFGLNDSYIYGKL
                     SQIDAIISDDKLDPETKKYYQQFTDIIN"
     gene            25274..25732
                     /locus_tag="VVR39_000503"
     CDS             25274..25732
                     /locus_tag="VVR39_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030045.1"
                     /translation="MYKMMLQPDLIRLDCSVSKHTELFQMVGKELEEKGYVTNQYLEA
                     LLEREQRFPTGLKTRFLNIALPHTDPEVIKEPFIFVVRNDKDLNMLQMGDNSDTPCQN
                     FLFLGIKDPKSQVGLLAKLMEIFSQEEFVQNFAQIKDGSEMYELLNQQLS"
     gene            25760..26062
                     /locus_tag="VVR39_000504"
     CDS             25760..26062
                     /locus_tag="VVR39_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6030046.1"
                     /translation="MARKLIVACGSGVATSTTIAEKIKTRFEDDGIDYPVEAVDYKSI
                     LNELPQASIYVYIAMPEQEVLDEAERLGVDVYPGVPFLTGMGADNVYEQIVESTNK"
     gene            26094..27443
                     /locus_tag="VVR39_000505"
     CDS             26094..27443
                     /locus_tag="VVR39_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6030047.1"
                     /translation="MEIFQNVIQWILNLGSAIFVPLIIFVLGLMVGMNIKKAFISAIT
                     LGVAFTGMGMIIGFMSNAVSPASEALAINTGISLPALDLGWTGAASIVWSWGYAFAFF
                     AVQIIINIIMLSFNWTKTLNVDMWNVWGKALTGYLVYYVSGQLWAGFLVAGLQVVLEL
                     KLGDMFQKHIEDLTGIPLVTVTHGMILSAVFMLPVNKLMDKIPFLNKKADTNALRKKL
                     GIFSENSVMGFIIGVLLGFAGAYSVSNSLNLGIQVATAMALFPMVSKLFMQALSPLAE
                     SMSEFMKKRFNDREVFIGMDWPLLAGRSEVWVTLILMVPFFIGYSLILPGNAVLPIAG
                     VLNYSIAVGGLLLTGGNLARMMILGIIYLPLCLYSATYFAPILTGLANKTGAVEVEAG
                     KLITWSSLESPELRILFAESFNGNILAIGGAVAFLLLFVWLYKTMVTQEVPSKRYEN"
     gene            27433..27678
                     /locus_tag="VVR39_000506"
     CDS             27433..27678
                     /locus_tag="VVR39_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030048.1"
                     /translation="MKTSKTLWYSLLFVALVLFLLGLNSGQYLYNFLAIIISFIVYKY
                     GYSDLFREYDEKQRAKRETSEKIYHALREGKKKEENK"
     gene            27675..28427
                     /locus_tag="VVR39_000507"
     CDS             27675..28427
                     /locus_tag="VVR39_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU6030049.1"
                     /translation="MTSGKILFEQERRAMAEAIELTFYRKNTNTAGGNFSFKTTDVNG
                     KEYIIMTPSMMSETYHGKVSAAQVLVLDLETQEVVAGEGKPTREINLHFACYETNPDI
                     KCVFHAHAPNAMFWATSHLDMPNLSEATQKVEYIKVLDFAPNTTPELAEIVRQELLEF
                     GNKLPKEYLLDSHGILVLTPGADGEEALNKALQIIDTVEWNAEIAYKQTIFQKLGILD
                     GYYSKGRKIGDIDDLINHRPIWNQEKKDEGFE"
     gene            complement(28537..29538)
                     /gene="galR"
                     /locus_tag="VVR39_000508"
     CDS             complement(28537..29538)
                     /gene="galR"
                     /locus_tag="VVR39_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU6030050.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLP"
     gene            29703..30881
                     /locus_tag="VVR39_000509"
     CDS             29703..30881
                     /locus_tag="VVR39_000509"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU6030051.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            30900..32381
                     /locus_tag="VVR39_000510"
     CDS             30900..32381
                     /locus_tag="VVR39_000510"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6030052.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIQDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            32451..32855
                     /locus_tag="VVR39_000511"
     CDS             32451..32855
                     /locus_tag="VVR39_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU6030053.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            33012..33866
                     /locus_tag="VVR39_000512"
     CDS             33012..33866
                     /locus_tag="VVR39_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEU6030054.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            33892..34662
                     /locus_tag="VVR39_000513"
     CDS             33892..34662
                     /locus_tag="VVR39_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6030055.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            34649..35515
                     /locus_tag="VVR39_000514"
     CDS             34649..35515
                     /locus_tag="VVR39_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEU6030056.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(35602..36864)
                     /locus_tag="VVR39_000515"
     CDS             complement(35602..36864)
                     /locus_tag="VVR39_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU6030057.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIAAALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(36864..37445)
                     /locus_tag="VVR39_000516"
     CDS             complement(36864..37445)
                     /locus_tag="VVR39_000516"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU6030058.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(37845..37940)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(38323..38562)
                     /locus_tag="VVR39_000517"
     CDS             complement(38323..38562)
                     /locus_tag="VVR39_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6030059.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(38562..38705)
                     /locus_tag="VVR39_000518"
     CDS             complement(38562..38705)
                     /locus_tag="VVR39_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6030060.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(38717..39544)
                     /gene="xth"
                     /locus_tag="VVR39_000519"
     CDS             complement(38717..39544)
                     /gene="xth"
                     /locus_tag="VVR39_000519"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU6030061.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            39678..40132
                     /locus_tag="VVR39_000520"
                     /pseudo
     CDS             39678..40132
                     /locus_tag="VVR39_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            40204..40581
                     /locus_tag="VVR39_000521"
     CDS             40204..40581
                     /locus_tag="VVR39_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU6030062.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVALKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            40787..42532
                     /locus_tag="VVR39_000522"
     CDS             40787..42532
                     /locus_tag="VVR39_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6030063.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKEMRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMAGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            42522..44273
                     /locus_tag="VVR39_000523"
     CDS             42522..44273
                     /locus_tag="VVR39_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030064.1"
                     /translation="MQNKQEQWAVLKRLMSYLKSYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYELLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            44447..45139
                     /locus_tag="VVR39_000524"
     CDS             44447..45139
                     /locus_tag="VVR39_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6030065.1"
                     /translation="MLKWEDLPVEMKSSEVEFYYQLVSKRKGSLIFKRCLALVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVMDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMLATLLL
                     PAGITSPASINYKDEDTIISQMTEKGLSADQAYVEHVLPEKMRYNLAYLREFSFLGDI
                     KIMFQTVFEVLK"
     gene            45182..46408
                     /locus_tag="VVR39_000525"
     CDS             45182..46408
                     /locus_tag="VVR39_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU6030066.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILHVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTLEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVENKRDLFVASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPAID
                     DEEMYKEFQILSLHGQTEDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            47538..49625
                     /gene="pfbA"
                     /locus_tag="VVR39_000526"
     CDS             47538..49625
                     /gene="pfbA"
                     /locus_tag="VVR39_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU6030067.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSLSVNSISSNGTIRSNSQLDNRTVESTVTS
                     TNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAIQDAIDAAAQGLGG
                     GNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIVFMTGLFTDDGAQV
                     EWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNSNNVTIKNVTFKDS
                     YQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEPLTRKGFPYALNDD
                     GKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKILNNHFDNMMYAGVR
                     FTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLLDLNKQVVIAENIF
                     NIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNIELLRVSDNLVVSE
                     NSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKEPVIRDSDGNFNIV
                     TENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNREFNSSKDNRQMNDKIDN
                     KQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKIMELFLTVTGIGLL
                     LTLKGLKYYGKDK"
     gene            49609..49905
                     /locus_tag="VVR39_000527"
     CDS             49609..49905
                     /locus_tag="VVR39_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030068.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
BASE COUNT        14855 a         9269 c        11056 g        14739 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaaatag gctccataat atctataagg gatttaccca ctacaaatat tatagagccg
      121 aaaaaggctg agatctggtg tctcagtctt ttatttcttg cgttttgcaa aatctacaaa
      181 tctaaatttt tctaacttat ggcgactttc ggtaaactga aattggcgtc cgtcttggag
      241 atagactttt gatttaatcg aaacgacata agggtctttg ccaatgtcca tgagaatctt
      301 gtctcggtcg cttgagtggt caatggtgat ttccttctga gcataatcaa taaggagttt
      361 gaggccattt tctatataag aatagataga ctgctcagca atttggcgag tgagatttgg
      421 aattagttcc atatccagat agtccgtatc cagaacggat accagatcat ccaccacacg
      481 ctggcggacc accttccaaa ccatccgaaa ctctgggaaa ccggttatca gtgaggattt
      541 tttatcaata ataatcttgt ccagactgac cacgttggtt ttagagcgca gtccaagttc
      601 tttaactagt tcttggtagc tggttaggtt ggatacaggg aaattgacgg tttcttcttt
      661 gacgacttga gaaccttgcc ctcttatctt tttgatcaat ccttcctctt ggaggagaga
      721 cagggccttt cggacggtat cacgactcac ttgatattgc tccataaggt cgtgctcgct
      781 aggaaggaaa tctccgacag cgtaagtctc gttttgaatg gtttcttgga tttgcttaaa
      841 taattgttgg tatttcttca ttttgcctgc ttaaataggt ttttagtcta gtttaatgaa
      901 cacctgtatc tattttacca tacaagtgct agaaaattta caaaaaaaca ccctttttat
      961 accaaacaag ttgcagacaa gtttggtatc gtttacaata tacttatcaa atcaaacttg
     1021 ctttgacaag tataaggaga atcaaatggg aaaatttgaa caagaagcca aagatctgct
     1081 tcaggcaatt ggaggcaaag aaaatgtgac tgccgtaact cactgtgcga cacggatgcg
     1141 ctttgtttta ggagatgata agaaggctaa tgttaaagct atcgagtcaa ttccagctgt
     1201 taaaggaact tttacaaatg caggtcaatt tcaggtaatc attggaaatg acgtgcccat
     1261 cttttataat gattttacag ccgtttcagg tattgagggt gtttccaaag aagcagccaa
     1321 gtctgcagct aagagtaatc aaaacgtggt ccaacgtgtt atgaccactc tggcggagat
     1381 ttttactccg attattccag ccttgatagt cggaggattg atcctcggtt tccgtaatgt
     1441 cttggaaggt gtccattggt cgatgttgga tggcaagacc atcacagaat cctctcagtt
     1501 ttgggcagga gtcaatcact tcctctggtt gcctggtgaa gctatcttcc agttcttacc
     1561 agtagggatt acttggtctg tttctcgtaa gatgggaacc agccaaattt tgggaattgt
     1621 tctcggaatc tgtttggtat cgcctcagtt gctcaatgcc tatgcggttg cttcaacgcc
     1681 agcagctgat atcgcggcaa actgggtttg gaattttggt tattttactg ttaatcgtat
     1741 tggttaccaa gcccaagtta tcccagcctt gcttgcaggt ttgagtctgt cttatcttga
     1801 aattttctgg cgcaaacata tcccagaagt catttccatg atttttgtac cttttttgtc
     1861 attgattcca gccttgattt tggctcatac tgttttggga ccaatcggtt ggacaattgg
     1921 acaaggactt tcatcagttg tcttggcagg tttaactggt ccagttaaat ggctcttcgg
     1981 tgcaattttt ggtgccctct acgctccatt tgtcatcaca ggtctgcacc atatgaccaa
     2041 tgccattgat acacaattga ttgcggatgc tggtggcact gccctatggc caatgattgc
     2101 tctttctaat attgctcaag gctcagccgt gtttgcctat tatttcatgc atcgccatga
     2161 tgagcgtgag gctcaggttt cacttcctgc aaccatttca gcctatctcg gtgttacaga
     2221 accagctctt tttggggtta acgtaaaata tatttatcca tttgttgctg ggatgactgg
     2281 ttcagccctt gcaggcatgt tatccgttac ttttaatgta actgcggctt ctattggtat
     2341 cggtggtttg ccaggtattc tctctattca acctcaatac atgctgccat ttgcaggaac
     2401 tatgctagtt gcgattgttg ttccaatgct cttgactttc ttcttccgca aggctggtct
     2461 ctttacaaaa acagagggcg atacgaactt gcaggcagaa ttcgttgctc aagaagaagc
     2521 agaatttgtg aaccatgaac cagtagaact tacttcggta gaaattatca gcccactaac
     2581 tggccaagtg aaagaattga gtcaagcgac ggatcctatt tttgcatcag gtgtcatggg
     2641 gcaaggtcta gtcattgaac caagccaagg tgagttgacc tctccagtta atgggacagt
     2701 gacggttctt ttccctacca agcatgccat cggcattgtc tctgacgagg gagttgaatt
     2761 gctcatccac atcggtatgg atacagtagg tcttgatggc aaaggttttg aaagtcttgt
     2821 agtccaagga gatcacgtta cagttggtca gcaactgatt cgttttgata tggatgtcat
     2881 taaggctgca ggtctggtga cagaaactcc tgttatcatc accaaccaag atgcttatac
     2941 agcgactatt cccggaactt atccgacaac gatccaagct ggagcatctc tcatggtcgc
     3001 tacacgaatc taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
     3061 caaaatagtg ttttgagcaa cctgtggcta gcttcctagt ttgttctttg attttcattg
     3121 agtataattg aaatagcaca aatagggacg gaagactgct tcctcccttt tatcagaaaa
     3181 ggagaaacag atgacacttg ataaaggaaa agtagtctat caaatctatc caaaatctta
     3241 caaagacacc actgaaaacg gtattgggga tttccgtggg attatcgaaa aaattcccta
     3301 tttagccaaa ctaggtgtgg atatggtctg gctcaatcca ttctatccaa gccctcaacg
     3361 ggataatggt tacgatattt cagattatat ggcagtggat cctctttttg gtgatatggc
     3421 tgattttgag gaaatggtgt gtgtcggtaa agagcacaag attgacttta tgctggacat
     3481 ggtacttaat cattgttcga cagagcatga atggtttcag aaagccctag ctggtgataa
     3541 gtattatcaa gactttttct tcatccaaga ccaatcaaca gattggcagt ctaagtttgg
     3601 tggttctgca tgggcgcctt tcggggatac tgggaaatac tatcttcacc tatttgatga
     3661 gacccaggct gaccttaact ggcgcaatcc caatgtccgt aaggagcttt tcaaggttgt
     3721 taatttctgg cgcgacaagg gtgtcaaagg ttttcgattt gatgtgatca atttgatcgg
     3781 taaggacgag gtttcagtgg actgtcctga aaatgaaggg aagccagctt atacagacaa
     3841 acccatcgtt cataactatt tgcgtatgat gaaccaagcc acttttggat ctgacgatag
     3901 ctttatgaca gttggggaaa tgtcttctac caccatggaa aactgtgtcc tttattcgtc
     3961 gcctgatcgt caggaattat ccatgacctt taattttcat cacctcaagg tggactataa
     4021 ggatggacaa aagtggacct tggctccctt tgattttgaa gagttgaaga gtctttacca
     4081 tagttggggt aaggaaatga gtgataaaga cggttggagt gccctctttt ggaacaatca
     4141 cgatcaacca cgtgccttga accgttttgt cgatattcaa aacttccgca aggaaggagc
     4201 caccatgcta gcagccagca ttcacctgtc acgtgggaca ccttatatct acatgggtga
     4261 ggaaatcggg atgattgacc cagactatga ttctatggct gattatgtgg atgtcgaatc
     4321 gcttaatgcc tatcagatgc tcttagaaga aggaaagagt cagcaagaag ccttccagat
     4381 tattcaagct aagtcgcgtg ataattcacg cattcccatg cagtgggatg cttcggaaaa
     4441 tgcaggattt tcaacaggca ctccttggtt gaaagctggt aaatcctata aatacatcaa
     4501 tgtagaaaat gaaatccagg gtccgatttt taccttctat caagacttga ttcgactgcg
     4561 taaggaaatg ccaatcattt cagaaggaag ttacaaacca gcctttgaag atagcaaaca
     4621 agtctacgct tttgaacgcc agtttgagga tcaaaagtta ctagtgctca ataactttta
     4681 tgctaaagaa gtggaaatcg acttgccagc agtctaccaa aatggacaga ttttgatatc
     4741 aaactatgaa gatgcagaag tgtctgagaa aattctactc aaaccctatc aaacactggc
     4801 tatttatgta aattaatact cttcgaaaat ctcttcaaac cacgtcagtt ttatctgcaa
     4861 cctcaaagcg gtgctttgag caacctgtgg ctagcttcct agtttgctct ttgattttca
     4921 ttgagtataa acttagcaag gagacctctt tttcagaaaa gcagcgttct ttttgctgtc
     4981 tattccatcc ttgaaagtgt agaacaaact ggtcagggtg gctagtttgt ggtataatga
     5041 aagggactca aaaagaaaca ggagaaaaat gatggattta cttttagcaa ttgtattgat
     5101 tgtgctagct tttctaggag gagctcttgg aggaatgtac ttggttcgta agcaaatcga
     5161 aaaagaattt gctgacaacc cacgtttgaa tgctgaagca gttcgtactc ttttgagtgc
     5221 aaatggtcaa aaaccaagcg aagctaaggt acaacaagtt taccaccaaa tcatccgcca
     5281 acaaaaggca gcccttgcta acaataaaaa gaaaaaataa ataaggaaaa gtctgggatg
     5341 aaagttccag acttctcact atgttggtta tggtttaggg atgagacttt ttccttgcat
     5401 tctattgata tttgattatg attaagagag aggtagttga cattctatca agctgtcggt
     5461 cagttcgttc agtacaagga atcataatga acgatcaatc agaaaaaaga ctagaaagaa
     5521 gactgtatgg ataatcgacc aattggtttt ttggattcgg gtgtcggggg cttgaccgtt
     5581 gtgcgcgagc tcatgcgcca gcttccccat gaagaaatcg tctatattgg agattcggcg
     5641 cgggcgccct atggcccccg tcctgctgag caaattcgtg aatatacttg gcagctggtc
     5701 aactttctct tgactaagga tgtcaaaatg attgtcattg cttgtaacac tgcgactgcg
     5761 gtcgtctggg aagaaatcaa ggctcaacta gatattcctg tcttgggtgt aattttgcca
     5821 ggagcttcgg cagccatcaa gtccagtcaa ggtgggaaaa tcggagtgat tggaacgccc
     5881 atgacggtac aatcagacat ataccgtcag aaaatccatg atctggatcc cgacttacag
     5941 gtggagagct tggcctgtcc caagtttgct cccttggttg agtcaggtgc cctgtcaacc
     6001 agtgttacca agaaggtggt ctatgaaacc ctgcgtccct tggttggaaa ggtggatagc
     6061 ctgattttgg gctgtactca ttatccactc cttcgcccta ttatccaaaa tgtgatgggg
     6121 ccaaaggttc agctcatcga tagtggggca gagtgcgtac gggatatctc agtcttactc
     6181 aattattttg aaatcaatcg tggtcgcgat gctggaccac tccatcaccg tttttacaca
     6241 acagccagta gccaaagttt tgcacaaatt ggtgaagaat ggctggaaaa agagattcat
     6301 gtggagcatg tagaattatg acaaataaaa tttatgaata taaggatgac caggactggt
     6361 atgttgggtc ttatagtatt tttggtggcg ttaacagttt gagcgactat cagacagatt
     6421 ttcctctgtt tgaattctcc aaaatatttg gagatgaaga gtatggtttc ccgctttcag
     6481 ttactgtttt acgctatggt tctacctacc gtttgttctc ctttgtggta gatatgctta
     6541 atcaagaaat gggacgaaac ttggaagtta ttcaacgtca tggggccctg ctcttggttg
     6601 aaaatgggca actcttgtat gtagaattgc ctaaagaagg ggtcaatgtt catgatttct
     6661 ttgagacaag caaggtcaga gaaaccttgt tgattgcgac tcgtaacgaa ggcaaaacca
     6721 aggaattccg agctatcttt gataagttag gctacgatgt ggaaaatctt aatgactacc
     6781 ctgacctgcc tgaagtagca gaaacaggta tgacctttga agaaaatgcc cgccttaagg
     6841 cagaaaccat ttctcaatta acgggcaaga tggttttggc agatgattct ggtctcaaag
     6901 tcgatgtcct tggtggctta ccaggcgtct ggtcagctcg tttcgcaggt gtgggagcaa
     6961 ctgaccgtga aaataatgcc aaactcttgc acgaattggc catggtcttt gaactcaagg
     7021 accgctcggc tcagttccac acaaccctag tcgtagccag cccaaataag gaaagtttag
     7081 ttgttgaagc agactggtca ggttatatta actttgaacc taagggtgaa aatggctttg
     7141 gctatgatcc cctcttcctt gtaggagaaa caggtgagtc atcagctgaa ttaaccctgg
     7201 aagaaaaaaa tagtcaatct caccgtgcct tagccgttaa gaaacttttg gaggtatttc
     7261 catcatggca aagcaaacca tcattgtaat gagcgattcc catggcgata gcttgattgt
     7321 ggaagaagtc cgtgatcgct atgtgggcaa agtcgatgcc gtttttcata acggcgattc
     7381 tgaactacgt ccggattctc cactttggga gggcatccgc gttgttaaag ggaacatgga
     7441 cttctacgcc ggctacccag aacgtctggt gactgagctt ggttcgacca agattatcca
     7501 aactcatggt cacttgtttg acatcaattt caactttcaa aagttggact actgggctca
     7561 ggaggaagag gccgctatct gcctctatgg tcacttgcat gtgccaagtg cttggatgga
     7621 aggcaagatc ctctttctaa atccaggttc tatcagccaa ccacgaggta ccatcagaga
     7681 atgtctctat gctcgtgtgg agattgatga tagttacttc aaagtggact ttttgacacg
     7741 agatcacgag gtgtatccag gtttgtccaa ggagtttagc cgatgattgc caaggagttt
     7801 gagactttct tgttggggca ggaggaaact tttttgaccc ctgctaaaaa tctagctgtg
     7861 ttgattgata cccacaatgc ggatcatgcg accctcttgc ttagtcagat gacctatacc
     7921 cgtgttcccg ttgtgacaga tgaaaaacag tttgttggga cgattggact cagagatatt
     7981 atggcttatc agatggagca tgacttgagc caagaaatca tggcggatac ggatatcgtt
     8041 catatgacaa aaacggacgt agcggttgtt tcgcctgatt tcaccattac ggaggtcttg
     8101 cacaagctag tagatgagtc cttcttaccg gttgtggata cagagggtat tttccaaggg
     8161 attattacgc gcaagtccat cctcaaggcc gttaatgccc tcttgcatga ttttagtaag
     8221 gaatatgaga ttcgatgcca atgagagaca ggatttcagc ctttttagag gaaaagcagg
     8281 gcttgtctgt caattccaag cagtcctata agtatgattt ggagcaattt ttagacatgg
     8341 taggtgagcg gatttctgag accagtctca agatttacca agcccagcta gccaatctaa
     8401 aaatcagcgc ccagaagcga aagatttcgg cctgtaacca atttctctac tttctctatc
     8461 aaaaaggaga ggtggacagc ttttaccgct tggaattagc caaacaagct gaaaagaaga
     8521 cggaaaagcc agagattcta tacctagact ctttttggca ggaaagcgac catccagagg
     8581 gccgcttgct agcgctctta atcctagaaa tggggctctt gcccagtgag attttagcca
     8641 tcaaggttgc ggacatcaat ctggattttc aggtgttgcg aatcagcaag gcttcccaac
     8701 agaggattgt caccattccc acggccttgc tttcagaatt ggaacccttg atggggcaga
     8761 cctatctttt tgaaagagga gagaaaccct attctcgtca gtgggccttt cgtcagttag
     8821 aatcttttgt caaggagaaa ggttttccat ccttatcagc tcaagtctta cgtgaacagt
     8881 ttattctaag acaaatagaa aacaaggtcg atttgtacga aattgcaaaa aaattaggat
     8941 taaaaacagt cctgacctta gaaaaatata gataatggat attaaattaa aagattttga
     9001 aggacccctg gacttgctct tgcatctggt ttctaagtac cagatggata tctacgatgt
     9061 gcccattacg gaagtcatcg aacagtatct agcctatgtc tcaaccctgc aggccatgcg
     9121 tctggaagtg acgggtgagt acatggtcat ggctagtcag ctcatgctga ttaagagtcg
     9181 taaactcctt ccgaaggtag cagaagtgac agacttgggg gatgacctgg agcaggacct
     9241 cctctctcaa atcgaagaat atcgcaagtt caagctcttg ggtgagcact tggaagccaa
     9301 gcaccaagaa cgagcccagt attattccaa agcgccgaca gagttgattt acgaagatgc
     9361 ggagcttgtg catgacaaga cgaccattga cctctttttg gctttttcaa atatcctagc
     9421 caagaaaaaa gaggagtttg cacaaaatca cacgacgatc ttgcgggatg agtataagat
     9481 tgaggacatg atgattatcg tgaaagagtc cttgattgga cgagatcaat tgcgcttgca
     9541 ggatttgttc aaggaagccc agaatgtcca agaggtcatc accctctttt tggcaaccct
     9601 agagttaatc aaaacccagg agctgatcct cgtgcaagag gagagtttcg gagatatcta
     9661 tctcatggaa aagaaggaag aaagtcaagt gcctcaaagc tagacttgat agagaggaaa
     9721 gatgagtact ttagcaaaaa tagaagcgct cttgtttgta gcgggtgaag atgggattcg
     9781 ggtccgccag ttagctgaac tcctctctct gccaccgaca ggcatccagc aaagtttagg
     9841 aaaattagcc cagaagtatg aaaaggaccc agattccagt ttggctttga ttgagacaag
     9901 tggtgcttat agattggtga ccaagcctca atttgcagag attttgaagg aatactctaa
     9961 ggcgcctatc aaccagagct tgtctcgggc tgcccttgag accttgtcca ttattgccta
    10021 caaacagccg attacgcgga tagaaattga tgccatccgt ggagttaact cgagtggagc
    10081 cttggcaaag ttgcaggctt ttgacctgat aaaggaagac gggaaaaagg aagtattggg
    10141 gcgccccaac ctctatgtga ctacggatta tttcctagat tacatgggga taaaccattt
    10201 agaagaatta ccagtgattg atgagcttga gattcaagcc caagaaagcc aattatttgg
    10261 tgaaaggata gaagaagatg agaatcaata agtatattgc tcacgcaggt gtggccagta
    10321 ggagaaaagc agaagagctg atcaagcaag gcttggtgac ggttaacggc caagtggtgc
    10381 gtgaactggc aaccactatc aagtcaggcg acaaggtcga agttgaaggt caacctatct
    10441 acaacgaaga aaaggtctac tatctgctta acaaaccacg tggtgtgatt tccagtgtga
    10501 cagatgataa gggtcgcaag acggttgtcg acctcttgcc caatgtcaaa gaacgtattt
    10561 accctgtggg tcgtttggac tgggatacat caggtgtctt gattttgacc aatgatgggg
    10621 actttacaga cgagatgatt caccctcgta atgagattga caaggtttat gtcgcgcgtg
    10681 ttaaaggtgt ggccaataag gacaatcttc gccccttgac ccgtggtctt gagattgatg
    10741 gtaagaaaac caagccagct gtttatgaaa ttctcaaagt ggacccagtc aaaaatcgct
    10801 ctgtggtgca gttgaccatc catgaagggc gtaaccatca agttaaaaag atgtttgaag
    10861 ctgttggtct ccaagtagat aagttgtctc ggactcgttt cggacaccta gacttgacag
    10921 gactccgtcc aggagaatct cgtcgtctta ataaaaaaga aatcagccaa ctacacacca
    10981 tggctgtaac taagaaataa tgaaacgaat tttaatagcg cctgtgcgct tttaccaacg
    11041 ttttatctca ccagtctttc caccctcttg tcgctttgat ctgacttgtt ccaactacat
    11101 gattcaggct attgaaaaac atggttttaa gggagtattg atgggcttgg ctcggatttt
    11161 acgttgtcat ccctggtcga aaacaggtaa ggaccccgtt ccagaccact tttcccttaa
    11221 acgaaatcaa gaaggggaat gaggtggggt aaatagattt caaaatgata aaaacgcatc
    11281 ctatcaggtt tgagtgaact tgataggatg cgttttagaa tgtcaaaatt ttatactctt
    11341 cgaaaatctc ttcaaaccgc atcagctttc atctgcaacc tcaaaacagt gttttgagca
    11401 acctgcggct agtttcctag tttgctcttt gattttcatt gagtattaaa ttgagtttga
    11461 agtggcttat ttcaaagctt tttgtatgtc ttcaatcatg agttttgttg attcaagtcc
    11521 gcctccgctt agataccaga ggtctggtgt tagttggata atcttaccat ttttagcagc
    11581 aggtgtttca gcgataaggg cattttctag gacaccgtcg ttgctagagt tgtccccacc
    11641 gatggcaagg gtacggttga tgacaaagag gatgtcaggg ttgatttctt tgacactttc
    11701 aaagctgact tcttgtccgt ggcgtgagtc ttcaaatttt gtatcagttg gtttgaattt
    11761 caaggtttgg tacaagaaag agaaacgaga tttggcacca aaggctgcca tttttccttc
    11821 attaaggagg atcgcaaggg cttttttgtc agagctttca tttttagtag cgacttcttg
    11881 gatactcttg tctagcttgg ccaattcttc cttggctttc tgtgtaccag tttcgccgaa
    11941 ggcacttgct aaggattcga tattagcctt ggtagaagtc cagtagtcgt ccttgcttgc
    12001 ttggaagaga acggttgggg cgatttcttt gaatttgtct acgaattttt gtgtacgtgg
    12061 tgaagcgata atcaaatcag gctcaagggc ggcgatagct tctaaatcag gttctttcat
    12121 agaaccaaca tttttgacag ttcccactag gtcttttaga taagtcggaa cagtttttgt
    12181 aggcattccg acgatatttt tttcaaatcc taaagcgcga atagtatccg cagcgccgag
    12241 gtcaaaggtc acaatctttt caggaacttt ggaaagtttg acctcgtcca gtgaactttt
    12301 aatggttacc tctgttggag cagagctact ggtctctgtc tgactagtgc ttgagtttgt
    12361 actacatgca ccaagtagga gcaagaagct ggccactagg gcagtgaaat aaagtttaag
    12421 ggatgttttc ataatttctc ctttttaaaa tgtgataacg atttagggag tctcttaatc
    12481 ttattgacta agagactgaa ggttctctaa cttgagcttt tatgttacta gctatagata
    12541 cagatctttt tgtcattgat atcagctagc gtgatgggaa tctcataaag ttgactgagc
    12601 aggtcagcct gcatgatttg atcggttctt cccttgctaa agacctggcc gtccttgaag
    12661 gcgacaattt catctgcata ctgactggcc atgttgatat cgtggaggac gatgataatg
    12721 gtcttgccga gttcctccac cagtcgtcga agaatctgca tcatgctgac gctttgcttg
    12781 atatcgagat tgttgagtgg ttcgtccagc aagataaagt ccgtatcctg ggccagtacc
    12841 atagcgataa agacgcgctg gagttgcccc cctgacaggc tattgatgta gcggtctttt
    12901 aagttggtca gttctaaata gttcagagtt tctcggattt tttcccagtc ttctgatcta
    12961 agtcgacctc ggctgtaggg aaaacgtcca aaactgacca gttcttcaac agtcaatttg
    13021 gcttggtaat tgattttctg ttttaggatg gttagttctt gggccagttc ttgcgaattc
    13081 cagctctcga tttcacgtcc tttgatactg agaactccct gatctttctt ggttagcctg
    13141 ctcatgatgg agaggagagt cgattttcca gcaccatttg gaccaataaa ggctgtcagt
    13201 ttttgaggac tgacttcaag cgaaatgcct tgcaaaatat cctgtttttg aatggatttg
    13261 tcaatgtttt ccagtttcac tgacgagacc tcctatatag taagataaag aataagaagc
    13321 cacccacact ctcaatgatc atactgatac gaatttccag tgcaaagact cgttcaatca
    13381 aggcttgccc caaggttaag ctaataaatc caaccagaat ggccactata aagagtaact
    13441 tgtgctgata gtctttgaca atcaggtagg tgaggttggc cagtataaag ccgaagaagg
    13501 ccataggtcc taccaaggca gtggccgttg aggtcaaaag cacgattccc cagaggagct
    13561 ctttctgttc tttttcaaca tcgagtccca atatctgagc cgtttctctt tgcaggtgca
    13621 agacatctag aacgactgct tttcgaaaga aaaagattgt caaagcgagg atgatcagag
    13681 aaccgatggc taggatggaa gtgttgagat gttgaaagga ggcaaaaaga ctattttgca
    13741 gtttatcgta ttcgtttgga tccattagga cttgaaggaa ggtgctgata tttcgaaaga
    13801 gacttctgag cgctagacag atcagcagga cgaagaccag gtcttgcttc atcagtgtct
    13861 tcaagtaacc ttgtaaggcg agaaagaaga gggactggac aagaagtaag actaggaatt
    13921 ctaagatagg ggatttgcca agttgaagaa acttgctttc aaaaaccagt agtagggttt
    13981 gtagtaggac gtagaaggat tcaattccca aaatactagg cgtcaggaag cgattttccg
    14041 tcagggtttg aaaactaatg gtcgaaatcc cagtcgcgat ggctaccaag agataaacga
    14101 tgatcttttg ggaacgcaac ttccaagcaa aggctgacaa gtgagtgatg ggccaaaagt
    14161 agagaagaca agctccgatg gcaagaataa tgagaatcca gaagagcttg gtatgtttgc
    14221 ttttagtctg catcttttcg tccccctctc cagagaagta ggataaagac gagactaccg
    14281 atgattccta gcaagagact gacagacaac tcatagggcc taatcagaac tcgggatagg
    14341 atatcgcaag ccagaactag attggcacca accagtgcga ccatgagttt ggtttgactt
    14401 agattatctc catagcgctt gcgaacaaga ttgggaacga taactccgag aaatggtagg
    14461 ccacccacgg taatcatggt gacgcttgtc gttagcgcca ccagaaagag ggccagtttt
    14521 tcaagtaggg agtaggaaat ccccaaactc tcgctggttt ctttccctag attcatgatg
    14581 gtgaaggttt gggataattt ccaaacggtt atcaggatga tgaggcctaa gaagagccac
    14641 tcatactgat gggtctgaat catggagaag gagccctggg tccaggcagt catactctga
    14701 accagattga aacgataggc gataacttct gtgactgagc cgataatccc gctatagatg
    14761 atcccaatca gaggcaacat ccacctttcc tttacagtaa aaatggtcat aaaggctagg
    14821 aagaagaggg tgaatacgat ggatgaaaca aaagcgaaga gcatcttgtg ggtcagacta
    14881 gccgatggaa agacaaaaag gctcagcacc attcccagtt tggcggcttc agtcgttcca
    14941 actgtactcg gtgcagcaaa ctgattttgg gtaatagtct gcatgagaag gcctgccata
    15001 ctcatactag aggcagtcag gagaatactg atagttcttg ggagacggga ctcttgaaag
    15061 aggagccagg tctgctggtc gaaatcaaat agctttcccc atgaaaaatc actggtccca
    15121 atgctaatag agagaaagac taggagtaga agtaagccaa ttaaataatg agaaagtttc
    15181 ataccccgtc ctttcatgta gatttggtat cgaaagatat ctgcggatat aaatgtaaca
    15241 ttatttttct aatctgtcaa taaaatttct gacaatttaa taaatacaac aaggagagag
    15301 caacaagact ttctcctttg ttatcctatt ctaaaatgtt tttaccttaa tctgataaaa
    15361 taatatcttc gagggagtag ctagccgtcc aatcaagata ttgtttagct tttgaagcat
    15421 ctgctaggac actggctggg tcactagcac gtcgagcaac aatctcgtgt gggatttttt
    15481 aatttagtaa ttcttcagca gttttaaaga tttctttgat agtatagcct tttttagttc
    15541 ctaagttaaa gatttgagaa gaactgtctt cttgaaatag gtagttcatt cctttaacat
    15601 gagcctatgc aaggtccaag acataaatgt aatctcgaat acatgaaccg tcacgtgtat
    15661 cgtagtcatc tccaaatatt tttaagctat cattttgtcc caatgcggtc ttgttgatat
    15721 ttggaatgat gtgagttgga tttttcacac gcagaccgtt tgaagcatcc atttcagccc
    15781 cagcagcatt aaagtaacgg aaaataacat atttccagtc gtagcgattg gccatccagt
    15841 aaatcattcg ttcgcccatc agttttgtct ctgcataagg gttgacaggg tcgagcaggg
    15901 tatcttcagt caccggcttg tcaatacagt tatttccata gagagaagca gtcgaagaga
    15961 acatgatttt ttgaatgcca acttcagata agactttgag aacttggttc ataccagcaa
    16021 cgttggcagt gaagtattta cttggatttt caatactttc gctcacaaca atttcacctg
    16081 cacaatggag gacagcatca atctgatttt cttctaagta agcctttaag gcgctagcat
    16141 cataaacatc cagttcttta aagctagcac gactatccac agtcgctcga tttcctgtgg
    16201 agagattatc gaggacatgc acctgatagc cagcatttaa aagagcttta acggtatggg
    16261 agccaatgta gctagtccca cctgtaacaa gaattgtttt ggtcatgatt ttttcctttt
    16321 ctagttttgt actatagtaa attgaaataa gatatgaaca actctattag gaaagtcaaa
    16381 ttaatttcta gaaatgtttt agcagctaca gcgtactatt ccaaactcaa ccaactatat
    16441 atttaaagaa agaagaaagg gaagtcaact attttctgta aatttcatga aaaatccaaa
    16501 caactttgat ggtgtattgt ttttttgttt ggaaataaat attcgagtta attttggaat
    16561 gtttactaga ttttgcacta catgcaagag aatactatcc ttttctaaga tagagcagga
    16621 ctaagatact aacttagaaa tccaccttcc cactatcctt ctcctataaa aagtggtaaa
    16681 atggatgaaa gaaagaagga actgaaatga caacattatt ttcaaaaatt aaagaagtaa
    16741 cagaacttgc tgcagtctca ggtcatgaag cgcctgtccg tgcttatctt cgtgaaaagt
    16801 tgacaccgca tgtggatgaa gtggtgacag atggcttggg tggtattttt ggtatcaaac
    16861 attcagaagc tgtggatgca ccgcgcgtct tggtcgcttc tcatatggac gaagttggtt
    16921 ttatggtcag cgaaatcaag ccagatggta ccttccgtgt cgtagaaatc ggtggctgga
    16981 accccatggt ggttagcagc caacgtttca aactcttgac tcgtgatggt catgaaattc
    17041 ctgtgatttc aggttctgtt cctccgcatt tgactcgtgg aaagggggga ccaaccatgc
    17101 cagccattgc cgatatcgtt tttgatggtg gttttgcgga caaggctgag gcagaaagtt
    17161 ttggcatccg tcctggtgat accatcgtac cagatagttc tgcaattttg acagccaatg
    17221 aaaaaaatat catctcaaaa gcttgggata accgctacgg tgtcctcatg gtaagcgagc
    17281 tagctgaagc tttatcaggt caaaaactcg gcaatgaact ctatctgggt tctaacgtcc
    17341 aagaagaagt tggtctgcgt ggcgctcata cctctacaac caagtttgac ccagaagtct
    17401 tcctcgcagt tgattgctca ccagcaggtg atgtctacgg tggtcaaggc aagattggag
    17461 atggaacctt gattcgtttc tatgatccag gtcacttgct tctcccaggg atgaaggatt
    17521 tccttttgac aacggctgaa gaagctggta tcaagtacca atactactgt ggtaaaggcg
    17581 gaacagatgc aggtgcagct catctgaaaa atggtggtgt cccatcaaca actatcggtg
    17641 tctgcgctcg ttatatccat tctcaccaaa ccctctatgc aatggatgac ttcctagaag
    17701 cgcaagcttt cttacaagcc ttggtgaaga aattggatcg ttcaacggtt gatttgatta
    17761 aacattatta aaccataagg gaggtggtag ggatggtaga accaaaccta gaaagcctta
    17821 taaaagatct ttacaatcat gctcgacatg atttgagtga agatttagtt gctgctctcc
    17881 tagagactac taaaaaactg cctactacaa atgagcaatt gcaggcagtt cgtctctcag
    17941 gcctggtcaa tcgtgaattg ctcctaaatc ccaaacatcc agcacctgag ttgctcaact
    18001 tggctcgctt tatcaaaaga gaagaagcca agtacagagg aactgcgact tctgcgctta
    18061 tgtatgagga actctttaaa atgctttgat tccattgtgg atcaaagcat tttttgtaag
    18121 acctatctcg tgagcgttca aatagtagta acaaggaatc atgagaagtc agccgagact
    18181 atagtagtga agaaacttct gtaatggaag tggagcgaag tgaggaatcg tcaaacggta
    18241 ggggataggc tgtttgaagg gtgctacgaa aaagataggg caaggtgaaa ttatagcggg
    18301 atgaaataag atatgaacaa attgattagg aaaatcaaat gaatttatag aaatatttta
    18361 gcagtcatag cgtcctattc cagtttcaaa atgttataaa tacgaacaaa ttgattggga
    18421 aattcaaatc gctttctatc aatgttttag aagatacagt gccctagtct aacttcaata
    18481 tactataaaa gaacagatgg aagcaattat gatttacttc tatctttaaa ataaatggtc
    18541 tgataggaaa aatgtgttcc ctcataaaat ataggatagt acgaatggaa ggcttttgta
    18601 gactggagga cgaaggagtt tagaaactct cgttaaaagt tagttgagcc ggagtatggt
    18661 ggtgtggata attatcaaaa attatttcta aatcgaaata gttgacagtt agaacgatga
    18721 gtgttacaat tgttttattc atttcgatat cgaaataaat tggaggtgtt atgaaagata
    18781 gtcatttgct agcccatcat attcgtttgt tgaatgggcg gatttttcaa aagttactga
    18841 gtcaagatct tgaggctctt tataggggtg aacagggcaa gattttagcg gttttatgga
    18901 atagtgaaac tggctgcgca actgcgacag atatcgcgct tgcgactggg cttgcgaata
    18961 atacgctaac gactatgata aaaaagctag aggaacaaaa gcttgtaatt gttagtccgt
    19021 gtggaaaaga caagcgtaag aagtatttag ttttaacgga gttaggcaag tcccagaaag
    19081 aagtggggca tcgtgtcagt cagaaattgg atactatctt ttacaaagga ttttcagagg
    19141 aagaaattca ccaatttgaa ggttttcaag aaagaatttt ggcgaatttg aaagagaagg
    19201 gaaatgaggt ttagaatatg tcacaacaag tgaaaaatgc tcacaaccta tacatccatg
    19261 ccattcaaga cggacgagtt gctgaggctc aagcccagtc tgtaggggat acctatatcc
    19321 aacattcgac aggtgttcct gacgggaaag aaggatttgc agccttcttt gcagatttct
    19381 ttgagcgtca tccagagagt cagattaaga ttgtccgcac cattgaggat ggcaatctgg
    19441 tctttgttca tgttcatcaa tatctgaatg gtggagaagc tcaatgggtg acgacggata
    19501 ctttccgtgc ggatgagaat ggtcgtattg ttgagcattg ggatgtcgtt gactactatc
    19561 gaacacctga aaatgatcaa ctagatcaaa tttttggaga ttttgaaatc aaggatttgg
    19621 ataagaaagc agaaaataaa aagctggttc gccgtttctt gacagaaatt ttccaaaatg
    19681 gggagctaga gcagtggagt gattatgtgg cagacgattt gattcagcat aatcatgaga
    19741 ttggacaagg aagtgctgct tataaaaact atgtggctga atatagtgtc acttttgact
    19801 ttgttttcca actcttagga caaggaaact atgtggttag ctatggtcag actcagattg
    19861 atggcgttgc ttatgcccag tacgatatct tccgtttaga gaacgggaaa attgtggagc
    19921 attgggataa taaggaagtc atgcctaagg tagaagactt gactaatcga gggaagtttt
    19981 aaattgagga caaagaatga ttgaatacaa aaatgtagca ctgcgctaca cagaaaagga
    20041 tgtcttgaga gatgtcaact tacagattga ggatggggaa tttatggttt tagtagggcc
    20101 ttctggatca ggtaagacga ccatgctcaa gatgattaac cgtcttttgg aaccaactga
    20161 tggaaatatt tatatggatg ggaagcgcat caaagactat gatgagcgtg aacttcgtct
    20221 ttctactggt tatgttttac aggctattgc tctttttcca aatctaacag ttgcggaaaa
    20281 tattgctctc attcctgaaa tgaaggggtg gagcaaggaa gaaattacga agaaaacaga
    20341 agagcttttg gctaaggttg gtttaccagt agccgagtat gggcatcgct tacctagtga
    20401 attatctggt ggagaacagc aacgggtcgg tattgtccga gctatgattg gtcagcccaa
    20461 gattttcctc atggatgaac ccttttcggc cttggatgct atttcgagaa aacagttgca
    20521 ggttctgaca aaagaattgc ataaagagtt tgggatgaca acgatttttg taacccatga
    20581 tacggatgaa gccttgaagt tggcggaccg tattgctgtc ttgcaggatg gagaaattcg
    20641 ccaggtagcg aatcccgaga caattttaaa agcgcctgca acagactttg tagcagactt
    20701 gtttggaggt agtgttcatg actaatttaa ttgcaacttt tcaggatcgt tttagtgatt
    20761 ggttgacagc cctatctcaa catttgcagt tgtcactttt gaccttgtta ctagctattt
    20821 tgcttgcgat tcccttggct gtttttcttc gctatcatga gaagctggcc gactgggtct
    20881 tgcagattgc aggtattttc cagaccatcc cgtctctggc cttgttgggg ctctttatcc
    20941 ctttgatggg aattgggacc ttgccggctt tgacagctct agtgatttat gcgatttttc
    21001 cgattttaca aaatactatt actgggctga agggaattga tccgagtctt caagaggctg
    21061 ggattgcctt tgggatgacc agatgggagc gtctcaagaa gtttgaaatt ccacttgcca
    21121 tgcctgttat catgtctgga attcggacgg cagcggtctt gattatcggt acggctacct
    21181 tggcgacctt gattggggca gggggactgg gttcctttat cctgttggga attgaccgta
    21241 ataatgccag tttgattttg attggggccc tttcttctgc agtgctagct attgccttta
    21301 acttcctact aaaagtaatg gaaaaagcga aattgcggac gattttctct ggttttgcct
    21361 tgatggcttt attactgggt ctgtcttata gtccagccct tttggctcaa aaagagaagg
    21421 aaaacttgat tattgctggg aaaataggcc cagaaccaga aattttggct aatatgtata
    21481 aattgctgat tgaagaaaat accagcatga ctgcgactgt taaaccgaat tttgggacga
    21541 caagtttcct ttatgaagct ctgaaaaaag gtgatattga catttatcct gaatttaccg
    21601 gtacggtgac tgaaagtttg cttcaaccat cacccaaggt gagtcatgag ccagagcagg
    21661 tttatcaagt ggcgcgtgat ggcattgcca agcaggatca tctagcctat ctcaaaccta
    21721 tgtcttatca aaatacctat gctgtagctg ttccgaaaaa gattgctcaa gaatatggct
    21781 tgaagaccat ttcggatttg aaaaaagtgg aagggcagct gaaggcaggc tttacgcttg
    21841 agtttaacga ccgtgaagat ggaaataagg gcttgcaatc aatgtatggt ctcaatctca
    21901 atgtggcgac tatgcagcca gctcttcgtt atcaggcaat tcagtcaggg gatattcaaa
    21961 tcacggatgc ctattcgact gatgcggaat tggagcgtta tgatttacag gtcttggaag
    22021 atgacaagca actcttccca ccttatcaag gggctccact catgaaagaa gctcttctca
    22081 agaaacaccc agagttggaa agagttctta atacattggc tggtaagatt acagaaagcc
    22141 agatgagcca gctcaactac caagtcggtg ttgaaggcaa gccagcagaa caagtagcca
    22201 aggagtttct ccaagaacaa ggtttgttga agaaataaaa ggagaggaat gtcagaggta
    22261 gccactttct tccctagaca aaagagcctg ggacaatagt ctcttatctc caaaaaaagc
    22321 aacggatttg ccgttgcttt ttttgcatgg ttacgatagt cttggtaaaa tagaattgct
    22381 taataaacca tttaaaaagg ctatcccatg catattcact ataacacaaa tcaaacaact
    22441 ttaccactag aaatcagttc cttcttacca caagaccatc tcgtctttac tattgaaaaa
    22501 gtggtgaata ccttggagga acgtcacttc tacacctcct atcatgcctt tgatcgcccg
    22561 tcttatcacc ctaaaatgct tgtatctact cttctatttg cctattcaca agggattttc
    22621 tctggtcgaa aaattgaaaa atggaagagt tagtgacctt agattgtttg tttattgacg
    22681 gaactaagat tgaagccaat gccaacaagt atagttttgt gtggaagaaa acgacagaga
    22741 aattctccgc caaacttcaa gaacagatac aagtctattt tcaagaagaa atcactcccc
    22801 ttctgattaa atatgccatg tttgataaga aacaaaagag agggtataaa gagtcagcta
    22861 aaaactgagc gaattggcac tataatgaca aggaggatag ctacatacat cctgatggct
    22921 ggtgctatcg ttttcaccat atcaagcacc agaaaacaca gacagacttt caacaggaaa
    22981 tcaaggttta ctacgctgat gaacctgaat cagcccctca aaaaggactg tatatgaacg
    23041 aacgctatca aaacttgaaa gctaaagaat gtcaggcgct tttatctccc caaggtagac
    23101 agattttcgc tcaacgcaag attgatgtga aacctgtctt tgggcagata aaggcttgtt
    23161 tgggtcacaa gagatgtaat ctgaggggca agcgtcaagt gagaattgac atgggattgg
    23221 tacttatggc caataacctc ctaaaataca ataagagaac gactcaaaat taaaaagcta
    23281 gagttccaca attggaaatc tctagctttt ttgtggtcga gaactatttt gtcccaggct
    23341 ccatgattta tggatttctt taataataac ttgagggatt aatttttcca caatttcttt
    23401 tcttgcgact cctacaccat tttccatagc atttgcagtt ccactagctg tagcatagcg
    23461 aatgatatcc tcgtccgata agttctgttc aaaagcatag atagctcctg ctacagtaga
    23521 gtctcctgac cctgttggat tgaccaaatt aatggatggt gcagtgacgt cgtataactt
    23581 accgttaaac tgggcgatgg ctccttgctc tccacaagac actagagtgt atgggatagg
    23641 agaaggcttg tccatcaagt agtctaatat ttcttgctta gtggtgacag ataatcctgt
    23701 taattggcaa aattcttcca tatttggttt gataaagtca ggaaggtgta ttgcatcgtt
    23761 aacaattttt tgtagggcag tttgtgaaaa atcagctaat atttttaatg tagaatcagt
    23821 gttttcacgt aagaattgaa tcaaatcatt atagaaatcc ctatcatctg aatgtacaga
    23881 gccatttaaa gagacgatgc tgatattctt ttccttgata acctgtaaca atgtatcaaa
    23941 gatttgtgat tttaaacctt ggtccacttt tgggcccgcc tcaacaattt ccgtatgaat
    24001 attgtcatta tgcatgatgg ttattgagtg acgagtctct ccgtcaatag gaatatataa
    24061 ggggtgaaac ttttcttgtg caagatgttg tttgaaaaac tcgccagatt taccaccgac
    24121 tagggttagt gcagtggcat ttattcccaa ataagagagg gcacgagcac agttgattcc
    24181 tttaccagcg gccataattg tagaattttg gaaacgatta tgagcaccta gtgtaaagtt
    24241 tttttcgaaa tagagtaatt cgatagatgg atttaatgta acgatgagaa tcatgggcag
    24301 atacctttct ttagttaata atatcggtaa actgctgata atatttcttg gtttctggat
    24361 ctaatttgtc atctgaaata atagcatcta tttggctaag ttttccataa atataggaat
    24421 cgtttaggcc aaatttagaa tgatcagcta gtaaataaac ttttctagat tgattcatag
    24481 caatagattg taaacgtcca ccaaaagatg aaaaagctgt taaatgatca tcaacgaggc
    24541 cattggttgc taagaatgca tagtcgatta gaaaatcttt tactagtctt tcagcatgct
    24601 caccatggaa ctcttccgtt tttgaaacaa actctccgcc agttaggagt atattttcaa
    24661 agttgtgttc atttagccaa ttaaaagtaa acaagctatt cgttataata tgcttatgtt
    24721 gatttttcag atgtttagca agtgctaaaa tagtagttcc agcgctaaga tagatgacac
    24781 tatttggctc aattaaatta gcagcaagtt gcgcgatgta atctttttct tcaggataaa
    24841 gcagacgctt ttcatcagtt gttttcgtat tgaatgttac ttttcgaaca ccgccgtgtt
    24901 ctttgataac tagattttct ttttctaatt ctgaaacatc tcttcgaatg gtcattgttg
    24961 agacgtgtaa tgattgcgca agttcctgat aggagatgac atcgctgttt tcaagcaaat
    25021 ttaaaatttc tttttttcta ttaattttca aaataaaggt tgctcccctc agtgaatttt
    25081 atagtactat cataacataa aattagaaaa gattagaatc taataagttt ataacaaaaa
    25141 atatcaaaag ataacaaaaa ataacaatta aagcattgac tttttaaatg aaaacgctta
    25201 taattacatt ataacaaaaa ataacagaat gttaacaata aatttaacgt ttttttaaaa
    25261 aaggagttgt gatatgtata aaatgatgtt gcaaccggat ttgatacggt tggactgtag
    25321 tgtatcgaag catacagaac tattccaaat ggttggaaag gagttggaag aaaagggata
    25381 tgtaacaaat caatacttgg aggctctatt agaaagggaa cagcgttttc ctacaggctt
    25441 aaaaacacga tttttaaata tcgcacttcc ccacacagat ccagaagtca tcaaggagcc
    25501 atttattttt gttgttcgca atgataaaga cttaaatatg ttgcaaatgg gtgataactc
    25561 tgatactcct tgtcaaaact ttctgttctt aggtataaaa gatcctaaga gccaggttgg
    25621 tctcttagct aaactaatgg aaattttttc tcaagaagaa tttgtacaaa acttcgctca
    25681 aataaaagat gggtcggaaa tgtatgaatt attaaatcaa caactatcat aaacaaaagc
    25741 ctaaaaagga gaataaaaaa tggcaagaaa attaatcgta gcatgtggaa gtggtgtagc
    25801 aaccagtaca acaattgctg aaaaaatcaa aacacgcttt gaagatgacg gtatcgacta
    25861 tcctgtagaa gcagtagatt acaaatcgat cttaaatgaa ctaccacaag caagtatcta
    25921 cgtctatatt gctatgccag aacaagaagt tttggatgaa gccgagagac tgggggtaga
    25981 tgtttatcca ggtgttccat tcttaactgg aatgggtgcg gataacgtat atgagcaaat
    26041 tgttgagtct acaaataaat aaaatataaa aataaattaa ggagaaaaag gttatggaaa
    26101 tctttcaaaa tgttattcag tggattttga atttaggatc tgcgattttt gtaccattga
    26161 taattttcgt tttaggttta atggttggta tgaatattaa aaaagccttt atttcagcca
    26221 ttactctcgg ggttgccttt acaggtatgg gaatgatcat tggatttatg tcaaatgcgg
    26281 tgtcgccagc ttctgaggct ctagctataa atacaggaat ttctctccca gctcttgact
    26341 tgggttggac tggtgcggca agtattgtat ggtcatgggg ttatgccttc gcattctttg
    26401 ctgtacaaat cattatcaat attattatgc tcagtttcaa ctggacaaag actcttaatg
    26461 tggatatgtg gaatgtttgg ggtaaagcct taacaggata tcttgtttac tatgtcagcg
    26521 gtcagttgtg ggctggtttc cttgtggcgg gattacaagt tgtgttagag ctaaagcttg
    26581 gagacatgtt ccaaaaacat attgaggatt taactggtat tccgctggta actgttacac
    26641 atggtatgat tctttccgcg gtattcatgt tgcctgttaa caaattgatg gacaaaattc
    26701 cattcttgaa taaaaaagct gatacaaatg ctcttcgtaa aaaattgggt atcttctctg
    26761 aaaactctgt aatgggattc attattggtg tgcttctcgg atttgcaggt gcctattctg
    26821 tatctaattc cttaaatttg ggtatccaag ttgcgactgc gatggcgcta ttcccaatgg
    26881 taagtaaact cttcatgcag gccctttcac cactggctga atctatgagc gaattcatga
    26941 agaaacgctt taatgaccgt gaagtattta ttggaatgga ctggccattg ttagcaggtc
    27001 gctcagaagt ttgggtaacg ttaatcttga tggtaccatt ctttattggc tattctctta
    27061 tcttgccagg aaatgcagtg ctcccaattg caggtgtctt gaactactct atcgctgtag
    27121 gcggactatt gctgacaggt ggtaacttgg cacgtatgat gattctaggt attatttatc
    27181 ttccgctttg tctctacagt gctacttatt tcgcaccaat cttgacaggg ttggccaata
    27241 agaccggagc agtcgaagtt gaagctggta aattgattac ttggtcatca cttgaatcgc
    27301 cagaattgcg gattctcttc gcagaaagct ttaatggtaa tattttagcc atcggagggg
    27361 cggttgcttt cctattactt tttgtatggt tgtacaaaac aatggtaaca caagaagtac
    27421 cgtcaaaacg ttatgaaaac tagtaaaact ctttggtaca gtctcttatt tgtagctctt
    27481 gtcttatttt tgctaggttt aaatagtggc caatatcttt acaatttttt agcgattatc
    27541 atcagtttta tcgtctataa atatggctac agtgacttat ttagagaata tgatgagaaa
    27601 caacgtgcga agagagagac atctgaaaaa atctatcatg ctttacgaga aggaaaaaag
    27661 aaagaggaaa ataaatgaca agtggtaaaa ttttatttga acaagaaaga cgcgctatgg
    27721 ctgaagccat cgaactgact ttctatcgca aaaacaccaa tactgctgga ggaaatttct
    27781 cctttaaaac gacagatgtt aatggtaaag aatacatcat tatgacaccg tccatgatgt
    27841 ctgaaaccta tcacgggaaa gtatcggctg ctcaagtgtt ggtgctggat ttagaaactc
    27901 aagaagtggt tgctggagaa ggcaaaccga cacgcgaaat caaccttcac tttgcttgct
    27961 atgaaaccaa cccagatatc aaatgtgttt tccatgctca tgcaccaaat gcaatgtttt
    28021 gggcaactag ccacttagat atgccaaact tatctgaagc tactcaaaaa gttgagtata
    28081 tcaaagtttt ggattttgcc ccaaatacta cacctgaact ggctgaaatt gtacgtcaag
    28141 aactcctaga gtttggcaac aaattgccaa aagaatactt actagacagt catggtattt
    28201 tggtattgac accgggtgct gatggagaag aggctttgaa taaagccctt cagattattg
    28261 atacagttga atggaatgct gaaattgcat acaagcagac aatcttccaa aagttaggaa
    28321 ttttggatgg ttactattct aaaggtcgta aaattggaga tattgatgat ttaatcaatc
    28381 atcgtccaat ttggaatcaa gaaaagaaag acgaaggttt cgaataaact atttgggagg
    28441 aggataggca cgtgctatct tcctttttaa aaaagaaatc ctaatggata tttgagaatc
    28501 tctattagga tttttggtct tattatatta gttgagttat ggcagagtac tttctcttaa
    28561 cgtcagtttg gttcccaaca tggtcaggct aggtattttc cgaccgtgga gtacttcctt
    28621 gttaagaata tccatacctg ctcgccccat ttcttcagta taaactgtaa tactagagag
    28681 gggaggatag acctgtttgg tcagactggt gtcgttgaat gaaatgaggc tgacgcgatc
    28741 tggcaggctg attccagctt cttggagggc acggagggca ccgatagcta aactatcgct
    28801 ggctgcgaaa aatgctggcg gaagttggtc tcccaagctc tgaatggcct ccttcattaa
    28861 gtcatagcca gactgggcag taaatcttcc ttgaaagacc agttcatcat gatagattcc
    28921 cctcgcttga ctgtagtttt tgaagttttc tagacgcttg tcctgaatga tttcttcttg
    28981 gtctgttgtt tcctcaagcc ctgttagaat cccgatgcgg tccatccctt gactgaggaa
    29041 ataatcgaca acctgtttca tagcagtgta aaaatccgtg ataatacagg tatgtcccag
    29101 ggaaagtgta tcgctgtcta gaaatacaag aggcttttgg tattcttcaa aggcagaaat
    29161 ctgagctcga ctaaactttc cgatgcagag aatcccaatc acttcctcgc ttaaggtaaa
    29221 aggatggtca ttaaaatagc gcaagatatc atagtccaac tcttgggctc ttttttctat
    29281 tcctaggcga atctggtagt agtagaggtc gtctagctcc ccttgttcgc tgacccattg
    29341 gataatggca atcttttgct tgggtttgtg ggactcgcct gtcttgaggt gcttggtgta
    29401 gcccagctct tcagcaacgg ttaaaatacg gtgtctggtt tcttctgtaa cagataggct
    29461 ctggtcgcgg ttgaggacac gggatacggt cgcgattgag acagaggcta gctgtgcaat
    29521 gtcttttaag gtagccataa atcctccttg attaggttag tatatcatat ttttcttctt
    29581 tttactgata ttttagtaaa attttagtaa aaaggattga ccttgggaaa ttccttggat
    29641 acaatagaaa gaaaacgatt acacgttaag atggcttaac ggacagtcaa aggagaattc
    29701 atatggcaca acatcttact actgaagtcc ttcgcaaaga ctttcttgct gtttttggtc
    29761 aagaagcaga ccaaaccttc ttttcaccag gccgtattaa tttgattggt gaacacacag
    29821 actacaacgg tgggcacgtt tttcctgctg ctatttcctt gggaacttac ggtgcagctc
    29881 gtaagcgtga cgaccaagtc ttgcgtttct actcagctaa ctttgaggac aagggcatta
    29941 tcgaagtgcc tctcgctgac ctcaagtttg aaaaagagca caactggacc aattatccaa
    30001 aaggggttct tcatttcttg caagaagctg ggcacgtgat tgacaaaggt tttgattttt
    30061 atgtttatgg gaatatccca aatggtgctg gcttgtcttc ttcagcatcc ttggagctct
    30121 tgacaggagt cgtggcagag catctctttg atttaaaact agaccgtttg gatttggtta
    30181 aaatcggaaa acaaacagaa aataacttta tcggagtcaa ctctggtatc atggaccagt
    30241 ttgctattgg tatgggggct gaccaacgtg ctatttactt agataccaat actttagaat
    30301 acgacttggt gccacttgat ttgaaggaca atgtcgttgt tatcatgaac accaacaaac
    30361 gccgtgaatt ggcggactct aaatacaatg aacgtcgtgc tgagtgtgaa aaagcagtgg
    30421 aagaattgca agttgccttg gatattcaga ccctgggtga attggacgag tgggccgttg
    30481 accaatatag ctatttgatt aaagatgaaa atcgtttgaa acgtgctcgc catgctgtgc
    30541 ttgaaaacca acgtaccctt aaagctcaag cagcccttca agcaggtgat ttggaaacat
    30601 ttggtcgttt gatgaatgcg tcacacgttt ctctggagca tgattatgaa gtaactggtt
    30661 tggaattgga tactcttgtt cacacagctt gggcacaaga aggagttctc ggtgctcgta
    30721 tgacaggggc tggttttggt ggctgtgcta ttgccttggt tcaaaaagat actgttgagg
    30781 cctttaagga agctgtaggc aaacactacg aggaagtagt tggatacgct ccaagcttct
    30841 atatcgctga agttgcaggt ggcactcgcg tccttgacta gtcaaaagga ggctctatag
    30901 tgatcttagt agataaattt gtaacacatg tcatttctga aagttcattt gaggaaatgg
    30961 atcgaatcta cctgaccaac cgtgttttgg cacgagtggg agaaggtgtt ttggaagttg
    31021 agaccaatct ggataaattg attgacctca aggaccagct agttgaggaa gccgttcgat
    31081 tagagacgat tgaggatagt cagactgcgc gtgaaatcct tggtactgaa ctgatggact
    31141 tggtgactcc ttgtccgagt caggtcaatc gtgacttctg ggaaacctat gtccactatc
    31201 ctgagcaagc gatacaggat ttttatcaac tcagtcagaa aaatgactac atcaaactca
    31261 aggccattgc taaaaatatc gcttatcgtg ttccatctga ttatggagaa cttgaaatta
    31321 ccatcaatct ctctaagcct gaaaaggatc cgaaagagat tgcggcagcc aagttggtgc
    31381 aagctagtaa ttatcctcag tgtcaacttt gtttagagaa tgagggttac catggtcggg
    31441 tcaaccaccc agctcgcagc aaccaccgga ttatccgttt tgaaatggtt ggtcaggaat
    31501 ggggtttcca gtattcgccc tatgcttact ttaatgagca ttgtatcttt ttagatggcc
    31561 agcatcgtcc catggccatt agtcgtcaga gttttgaacg tctgttggct atcgtagagc
    31621 agtttccagg atattttgct ggatctaatg ccgacctgcc gattgtgggg ggctctattc
    31681 taactcatga tcattatcag ggaggccgtc acgtatttcc tatggaattg gctcccttgc
    31741 aaaagacctt ccgatttgct ggttttgagc aggtcaaggc tggaattatc aagtggccaa
    31801 tgtctgtcct acgcttgact tcggattcca aagaggattt gattaactta gctgataaga
    31861 ttttccagga atggcgtcag tattcagatt ctagtgtgca gattttagca gagacagacg
    31921 ggacaccgca tcacaccatc acaccaatag cgcgtaagcg tgatggacag tttgagttgg
    31981 acttggtctt gcgagacaat cagacttcag cagagcatcc tgatggcatc tatcatcccc
    32041 acaaggatgt ccaacatatc aagaaggaaa atatcggctt gattgaggtc atgggcttgg
    32101 caatcttgcc accacgtctg aaagaagaag tagagcaagt cgctagctat cttgtaggag
    32161 aagctgttac agttgccgat tatcatcagg agtgggcaga ccaactcaaa tcccaacatc
    32221 cagacctaac ggataaagaa aaagcccttg caatcgtcaa ggactctgtg ggtgctatct
    32281 ttgcgcgtgt acttgaggat gcaggagtct acaagcagac agaacaaggg cagacagcct
    32341 ttatgcgctt tgtggaacat gtcggaattt tactagacta ggagctttct ccttgcacag
    32401 tcctataaaa agtagtatca tagtgtcatt tgaaatatca ggaggaaacg atgaaagact
    32461 ttcattttga cgctatatct gcctttgaaa attacgaaat tgaaaaaatg agagatggtc
    32521 acgttgtggt gacgaccaaa gtagtgaact cgtcgctcaa ctactatggc aatgcccatg
    32581 gtggctatct attcacacta tgtgaccaaa tcagtggttt ggtggttatc tcgctgggac
    32641 ttgatggggt gacactccaa tcctctatca actaccttaa ggcaggaaaa ctcgacgatg
    32701 tattgaccat taaaggagaa tgtgtccatc aaggtcgtac aacctgtgtg atggatgtgg
    32761 atatcaccaa tcaagagggc agaaatgtct gcaaagcaac ctttactatg tttgtcacag
    32821 gccaaaggtc tgaggaaaga cgggtaagga tataaagagt aatttaatag agtgaggtga
    32881 attttggaat ttataagatt tgccttactc atttttttat attgatatga tttaattcta
    32941 aaatagaaaa tttagtaatg tggtagaaaa tacaagagtt gtgttttaat ttctatggta
    33001 taattaaaag catgaagata aaagaaataa agaaagttac tttacaaccg ttcacgaaat
    33061 ggacaggtgg taaaagacaa ttattgcctg ttattagaga attaatgcct aaaacctata
    33121 acaggtattt cgaacctttt gttggaggtg gagctttatt ttttgatttg gctcctaaag
    33181 atgcagttat taatgatttt aacgctgaac taataaattg ctatcaacaa attaaggaca
    33241 atcctcaaga attgattgaa attttgaaag ttcatcagga atataattca aaagaatatt
    33301 atttagattt acgttctgca gatcgtgatg aaagaataga tatgatgtcc gaagtacaaa
    33361 gagctgcacg tattctatat atgttgagag tgaactttaa tggtctatat cgtgtgaatt
    33421 ctaagaacca atttaatgtt ccatatggac gttataagaa tcctaaaatt gttgatgagg
    33481 aattgatatc tgctatttca gtttatctaa ataacaatca actagaaatt aaagtgggag
    33541 attttgaaaa ggcaattgta gatgttcgaa caggagattt tgtgtatttt gaccctccat
    33601 atattccatt gtctgagacg agtgcattta cgtcttatac tcatgaggga ttctcttttg
    33661 cagatcaagt aagattaaga gatgccttta agagattgag tgatacagga gcttatgtta
    33721 tgttatcaaa ttcttctagt gctttagtag aggagttgta taaggatttt aatatacatt
    33781 atgttgaagc tacccgaact aatggagcaa aatcttcaag tcgaggaaaa atttctgaaa
    33841 ttatagtcac aaattatgaa aaataacgaa tataagtatg gaggtgttct tatgacaaaa
    33901 ccatactaca ataaaaataa gatgattctt gttcattcag atacgttcaa gttcttatca
    33961 aaaatgaaac cagaaagtat ggatatgatt tttgctgatc caccttattt tttaagtaat
    34021 ggtggaatat ctaattctgg gggacaagtt gtttctgttg ataaaggaga ttgggataaa
    34081 atttcttcat tcgaagaaaa acatgagttt aatcgtaaat ggattcgcct agcaaaagaa
    34141 gttctgaagc ctaatgggac ggtatggatt tcaggtagtt tgcacaacat atactcagtt
    34201 ggaatggcat tagaacaaga aggttttaaa attctgaata atattacttg gcagaaaaca
    34261 aaccctgccc ccaatttatc ttgtcgttat tttacccatt ctactgaaac cattttatgg
    34321 gccagaaaaa atgataaaaa agctcgtcat tactacaatt atgatttaat gaaagaattg
    34381 aatgatggaa aacaaatgaa agatgtctgg acgggttctt taacaaagaa agttgaaaaa
    34441 tgggctggga aacatccaac tcaaaaacca gagtatttgt tagaacgcat tattttagcc
    34501 tctactaaag agggtgacta tattctagac ccatttgttg gtagtggcac tacgggtgtt
    34561 gttgcgaagc ggttaggtag aagatttata ggtatcgatg ctgaaaaaga atatttaaaa
    34621 attgcaagga agaggttgga ggcagaaaat gaaacaaact agaaattttg atgagtggtt
    34681 gtcaacgatg accgacacag tagctgactg gacttattat acagattttc ccaaggttta
    34741 taaaaatgta tctagtataa aagttgctct aaatattatg aatagtctta ttggtagtaa
    34801 aaatatacaa gaggattttt tagacttata tcaaaattat ccagaaattt tgaaagttgt
    34861 gcctctactt attgctaaac gtttgagaga tacgattatt gttaaggatc cgataaaaga
    34921 tttctatttt gattttagta aacgaaacta tagtattgaa gaatatacta tgtttttgga
    34981 aaaatcaggt atatttgatt tattgcaaaa tcatttagta tcaaatttag ttgactacgt
    35041 tacaggtgtt gaggttggta tggatactaa tgggcgcaaa aatcggactg gagatgcgat
    35101 ggaaaatatt gttcaaagtt atcttgaagc tgaagggtat attttaggag agaatttatt
    35161 taaagagatt gaacaaaatg aaatagagga aattttttct gtcgatttat ctgctattac
    35221 gaatgatggg aatactgtga aacgttttga ttttgtcata aaaaatgaac aagtgcttta
    35281 tctgattgag gttaattttt attcaggaag tggttcaaaa ttaaatgaga cggctagatc
    35341 ttacaaaatg attgctgaag aaattaaagc tattcctaat gttgagttta tgtggattac
    35401 tgatggacaa ggttggtata aggctaagaa taatttacga gaaacatttg atattttacc
    35461 attcttatat aatattaacg atttggaaca taatatttta aagaatttga aataggtcca
    35521 attcaattag atgggaattg ggattgattg tatttataat caatttgtga taaacaaaaa
    35581 agaggctcgc acctcttttt cttatttctt tttatgattt aatacggcat tgaggacaat
    35641 ggcgagtagg ctggctacga cgattccgtt tgagaagaac atttggaagg ctgtcggcat
    35701 gctgacaaag agattactgt tgttgagacc gacacctgca gcgattgaaa cagctgcgat
    35761 aaggaagttg tgttcattgt tagcaaagtc aactcgggct aggatttgca tcccttgaat
    35821 agatacaaaa ccaaacatca ccagcatggc accgccgagg acggagcttg gaatgatttg
    35881 ggcaagggca ccaaacttag gaagcagtcc aaggagaacc aggaaaccag ctgcgtagta
    35941 gattggcagg cgttttttga tgcctgacaa tttaaccaaa ccaacgtttt gtgaaaatcc
    36001 ggtgtaaggg aaggtgttaa agattcctcc gagaagtacg gccaaacctt ctgcgcggta
    36061 accgttgcga aggcgcgtgc tgtcgattgg atcttttgtg atatcagaca aggctagata
    36121 aacaccagtt gactcaacca tagacaccgt tgcgatgata cacatcatga caatagatga
    36181 gatttcaaag gttggcatcc caaagtagag tggagttggg acatggacaa gtggagctac
    36241 cgcaacagga gagaagtcca ccaagcccat agtagcagca atggcagttc caacaaccag
    36301 accaatcaaa atagagatag acttgataaa tcctttggta aagatgttga tcaagaggat
    36361 aatcagaaca gtaatagctg aaagcaagag actttgacca gttggctctg gaacgttatt
    36421 tcccatattt ccaatagcga cagggatcaa ggttaaacca atcgtggtaa taacagatcc
    36481 tgttacgata gaggggaaga gattggccac ttttgagaag atgcctgaaa caagaaccac
    36541 gtaaatccca gatgcgataa gggcaccaaa catagcgcca ctaccatggc tttgcccaat
    36601 cataatcaag ggagcgaccg actggaatgc aactccaaga acgactggga gtccaatccc
    36661 aaagtatttg ttgagttgga gttggaggaa ggttgccacc ccacacatga agatatctgt
    36721 agaaatcagg taggtcaact gctcagctga atagccaagg gctgccgcaa tcatgatggg
    36781 aaccaggata gatcctgagt acatggctag taagtgctgc aagccaagaa cggctgcttg
    36841 cgagtgtttt tcttgagttt gcattagaga tctgcctcct taaatacgac ctgaccattt
    36901 tcaaaacgat ccaaacgagc aagtgatagg acagggtagc ctgctttttc aagcaaatca
    36961 cggccatctt ggaaggattt ctcaatcacg ataccgatag cttggactgt ggcaccggcc
    37021 tgttcgatga tttgaatcaa gcctttagca gcttggccat tagcaaggaa atcgtcgata
    37081 atcaaaacct tatcttctgg tgagaggaat tttccagcga tagaaacggt gctggtcacc
    37141 tgtttggtaa aggagtagac ttgagcagtt aagatgcctt cgttcatggt gatgttctta
    37201 gcttttttgg cgaaaatcat gggaacgttt aaggcttcag ctgtaaaaac ggctggggca
    37261 atacccgacg cttcaatggt tacgaccttg gtaatgccag tagcagcaaa tttttccgca
    37321 aaaaccttac caatctctcg catcaagcta aagtcaactt ggtgggttaa aaaggaatct
    37381 accttgagga tgttatcacc caagatatgc ccatccttga ggatgcgctc ttctaataat
    37441 ttcataagac ctcctaaagt ctaaaagtta atttacttgt tgtttaaata tttctatagt
    37501 gatccctttt gctaatacta tatatttgat aaaactatta cgagcgaagc gagtcttatc
    37561 aaatatttcc cgttgtagtg gtatcataga caatgatctt gttattgtct atgacgggat
    37621 ttttgagagt aaaatagttc ggggaactat tttagcctaa gcctagaaat gaaagagcta
    37681 ggggctcaaa aattagggat gaaattccct ggattcctga aattattcac aggataattt
    37741 cacctctcgt ccgcactaat taagggaaat attaaaaata ttcaaaaaag acctacttaa
    37801 tctctaagta agtcccctaa atagacatgg caaaaacggc catatctcac tgctgactta
    37861 cttattgtta ggtgttccgg caccttgtag aaacgtcgtg ccaattcacg acataaacaa
    37921 gtaaaacgat attcaatttt aaataggctt gagccaatgt ttttatttta cactaaataa
    37981 ctttagaaat caactatttt gttagtgttt tggtttaaaa aacgaacaaa cagaagagag
    38041 ggtgaacaaa aactccgttg taagctaaca tttatactaa atgaaaatca aagagcaaac
    38101 taggaagcta tccacaacct caaaacactg ttttgaggtt gtggatagaa ttgacagagt
    38161 cagtatcata tacctacggt aaggcgatgt tgacgtggct tgaagagatt ttcgaagagt
    38221 attagaagat ttttccatca taaaaggcat actatcaagt ttttagacac ctgacaatat
    38281 gcctttttct aactttaaag acttttccca atttttatta ttctactcgc taaatcttaa
    38341 aaaatagcca tctggatcca aaactgcaaa tttatgagga tagatatagg gatcactgac
    38401 acgaaacttt cttttggtca agggacgata aataggatag tttgcctcca tcactttttg
    38461 atagagtttt ggaacatcct ttatgccaaa ggagagattg actccacgac caaaggggta
    38521 ggtcagttca gctagttgat cctttgttcc ctcctctaac attagttgac actcttcaag
    38581 agaaagagaa agttttcttc tggacgttgg tattcaatcc taaaacccag taaaccacag
    38641 tagaaggacc gggactgttc gatattcgat acaagaaact cgggaatgac cgcattgtag
    38701 tccatataga aaatccttac aagtcaattt ccaagacaat cggtgtatgg tcttggcgag
    38761 cacctgagtc aatcatatca gatttagtga ccttgtcagc gatacggtta cttgtgagcc
    38821 agtagtcgat tctccagcct gtattgttga ttttagaagt tttgctgcgt tgtgcccacc
    38881 aagtgtagcg ttcaggaaca tcgccatgaa catggcggaa ggtatcagta aatccagttg
    38941 ccaataggtt ggtaaatcca gcacgttcct cgtcagtaaa tccaggtgaa cggcggttgc
    39001 tagcaggatt tgcaaggtcg atttcattgt gggctacgtt gtagtcaccg gtcgcaagga
    39061 ctggtttttc tttgtctagt tcagccaaat actccgcata tttgacatcc cagacttggc
    39121 gttcttccaa gcgtttaaga ccatcgccag catttggtgt gtaaacttgg gtcacgaaaa
    39181 atgcatcaaa ttctagagtg atgatgcggc cttccaagtc catggtagaa ggggcaccga
    39241 tttctgggaa agtgacagtg ggtgtaagtt ctttcttata aaggaacatg gttccagcat
    39301 agcctttacg ggcaggctct tgggaagagc gccacgtgtt ttcgtagcct gggaagagtt
    39361 cttctaaaat ttccacgtgt ttctttgtag gtcctttggc agaaagcttg gtttcttgga
    39421 tagcaatgat atcagcattt tcagcgacca aggtttgtag gacttcttgg gacaatttgg
    39481 cacgagctga gtcactagtt agggcagcgt ttagggaatc aatattccat gagataagtt
    39541 tcataaagtt acctttttca ttcagattat agattttatt ataccaaaaa aagatctatt
    39601 tccccaacgt atggtttgaa aaattactct ctttcgttta taattaagaa tgattttatg
    39661 aaagggagtg aaaatacatg aaattctact cttatgacta tgtactcagc caaatcggtc
    39721 agcaaaatgg tatcatggtt ggctttggga ttgttctatt agctgtgaca gtttttttgc
    39781 tttcaaggca taccatgata aaaaggaacc gaatttcgtg agttggtcat gatttcagct
    39841 ctggccttat ttagctctgc ttttggtcag catcacgact tatcaaaaca atcaagtttc
    39901 taacaataaa tttcaaactt cacttcattt catcgaggtt gtttccaaag atttgggagt
    39961 agacaagtca gaagtctatg ttaatacttc cacaaacaca gatggcgcac ttatcaaagt
    40021 gggagatcgc tattatcgtg ccctaaacgg aagtgagcca gacaagtacc tgttagagaa
    40081 agtcgaattg tataagacag acgcaattga actggtggat gtgaacaaat gacacttaat
    40141 tatatcgaaa ttttaatcaa actggtcttg actctcaaat agctcaacaa caatgttcac
    40201 tttgtgaaac gtttgattga tggtaagcca actctcctta tcaaaaatgg gaatattgac
    40261 ccagaagcct gtcgttcagt tggtttgtct gcatcggatg tagccctcaa acttcgtagc
    40321 caagggattt tccagatgaa gcaagtcaaa cgagctgtgc aagagcaaaa tggacaactt
    40381 atcgttgtgc aaatgggaga tgaaaatcct aagtatccag ttgtgactga cggtgtgatt
    40441 caagtagatg tcttggaatc gattggtcgt agcgaagagt ggttgcttga taacctcagt
    40501 aaacaagggc atgacaatgt agccaatatc tttattgctg aatatgacaa gggtgctgtt
    40561 acagtcgtaa cttatgaata agaaaaacct ggggtcttgt actcttcgaa aatctcttca
    40621 aaccgcgtca acgtcgcctt gccgtatgta ggttactgac ttcgtcagtt ctatctacaa
    40681 cctcaaagca gtgctttgag cagcctgcgg ctagtttcct agtttgctct ttgattttca
    40741 ttgagtattg gcctcaggtt tccatttgca atcagaaagg gattttatgt ccattattca
    40801 aaaactctgg tggtttttca agttagaaaa acgccgttat ctagtcggaa ttgtggccct
    40861 ggtcttggtt tccgtcctca atctcattcc tcctatggtt atggggcgag tcattgatgc
    40921 catcacatcg gggcaattaa cccagcagga cctccttctt agcctatttt acttgctact
    40981 tgcagccttt ggtatgtact atttgcgcta tgtgtggcgt atgtatatcc ttgggacctc
    41041 ttattgcttg ggacagatca tgcggtctcg cttgtttaag catttcacaa aaatgtcgtc
    41101 agccttttat caaacctatc ggacgggtga tctgatggca cacgcaacca atgatatcaa
    41161 tgccttgact cgtttagcag gtggcggtgt catgtctgcg gtggatgcct ctatcacggc
    41221 tctggtgact ttgttgacca tgctctttag catctcatgg cagatgactc ttgttgccat
    41281 tctcccccta cctttcatgg cctatgcgac tagtcgccta gggagaaaga ctcataaggc
    41341 ctttggcgaa tcccaagctg ctttttctga actcaataac aaggtacagg agtccgtatc
    41401 aggtatcaaa gtgaccaagt ctttcggtta tcaggcagac gagttgaagt cttttcaggc
    41461 agtcaatgaa ttaaccttcc aaaagaacct gcaaaccatg aaatatgata gtctctttga
    41521 ccctatggtt ctcttgtttg ttggttcgtc ctatgtttta acgcttttgg ttggctcctt
    41581 gatggttcag gaagggcaga ttacagttgg taatctagtc acctttatca gctatttgga
    41641 tatgctggtc tggcctctta tggccatcgg cttcctcttt aatactactc agcgagggaa
    41701 ggtttcttac cagcggattg aaaatctttt gtctcaggaa tctcctgtac aagaccctga
    41761 gtttcctctg gatggtattg aaaatgggcg tttggagtat accattgaca gctttgcttt
    41821 tgaaaatgag gaaacactga cggatattca ctttagtttg gcaaaagggc aaacactggg
    41881 cttggttggg cagacaggct ctgggaaaac gtccttaatc aagctcctct tgcgtgaata
    41941 cgatgtggat aagggtgcca tttatctaaa cggtcacgat attcgggact atcgtctgac
    42001 agaccttcgc agtctcatgg gctatgttcc tcaggaccag tttctctttg caacttcaat
    42061 cctagacaat atccgctttg gcaatcctaa cttgcccctt tcagcggtcg aggaagctac
    42121 taagctagcc cgagtttacc aagatattgt agacatgcct caaggatttg atacgctgat
    42181 tggtgaaaaa ggagtcagtc tttctggtgg tcaaaagcaa cggttggcta tgagtcgggc
    42241 tatgatttta gaccctgata tcttgatttt ggatgattcc ttatccgccg tagatgccaa
    42301 gacagagtat gcgattatcg acaacctcaa ggagatgcga aaggacaaga caaccattat
    42361 cactgcccat cgcctcagtg ctgttgtcca tgcagatttt attttagttc tacaaaatgg
    42421 tcaaattatc gaacgaggca ggcacgaaga cttgctagcg atggctggct ggtatgccca
    42481 aacctaccag tctcagcagt tggaaatgaa aggagaagaa gatgcagaat aagcaagaac
    42541 agtgggctgt attgaagcgc ttgatgtctt atctcaagtc ttatggactc ctgacctttt
    42601 tggcactcag ttttctccta gcgacgacgg tcattaaaag tgtcataccc ctcgtggctt
    42661 cccactttat cgaccagtat ctcagcaatc ttaaccaact agccgttacc gttttgctgg
    42721 tctactatgg tctctacatc ctacaaactg tagttcagta tgtcggcaat cttctctttg
    42781 cgcgcgtgtc ttacagtatt gttagggata ttcgtcggga tgcctttgcc aatatggaga
    42841 aactgggcat gtcttacttt gacaagacgc cagcaggttc tatcgtttct cgtttgacca
    42901 acgataccga gacgattagt gatatgtttt ctgggatttt atctagcttt atctcagcag
    42961 ttttcatctt tctgacaact ctttatacca tgttggtatt ggattttcgt ttgacagcat
    43021 tagtcttgct ctttctcccc ttgattttcc ttttggtcaa tctctatcgg aaaaaatcag
    43081 tgaaaatcat tgagaaaacc agaagtctct tgtcagatat caatagtaag ctggcagaga
    43141 atatcgaggg aatcaggatt attcaggcct ttaatcaaga gaagcgcctg caggcagaat
    43201 ttgatgaaat caaccaagaa cacttggtct acgccaaccg ttctgtagcc ttggatgccc
    43261 tctttttgag acctgccatg agtttgctga aacttctagg ctatgcagtc ttgatggcct
    43321 actttggcta ccgtggtttt tctatcggga taacggtcgg gaccatgtat gcctttatcc
    43381 agtacatcaa ccgccttttt gaccccttga ttgaggtgac gcaaaacttt tcaactctgc
    43441 aaacggctat ggtttctgca ggtcgtgtct ttgccctgat agacgagagg acctatgaac
    43501 ttcttcaaga aaatgggcaa gccaaagtcc aagaaggcaa tatccgtttt gaacatgtgt
    43561 gtttctcata tgacggtaaa catccgattc tggatgacat ttctttctct gttaataagg
    43621 gtgaaaccat tgcctttgta ggtcatacag gttcagggaa atcgtctatt atcaatgtcc
    43681 tcatgcgctt ttatgaattc cagtcaggga gagttctctt ggatgatgtg gatatcaggg
    43741 atttcagtca agaagagctg agaaaaaaca tcggtttggt cttgcaggaa cccttcctct
    43801 atcatgggac tattaagtcc aatatcgcca tgtaccaaga aatcagtgat gagcaggttc
    43861 aggctgcggc agcctttgtg gatgcagatt cctttattca agaacttcct caggggtacg
    43921 actcccctgt ttccgagcgt ggttcgagct tctctactgg gcaacgccag cttcttgcct
    43981 ttgctagaac agtcgccagc cagcctaaaa tcctgatttt ggatgaagcg acagccaata
    44041 ttgactctga aacagaaagc ttggttcaag cttctctggc gaagatgaga cagggccgaa
    44101 caactattgc tatcgctcac cgcctttcta ctattcaaga cgccaactgc atctatgtct
    44161 tggataaggg acgcattatc gagagtggaa cccatgagga actcttgact ctgggaggaa
    44221 cctatcacaa gatgtatagt ttgcaggcag gggccatggc ctatactctt tgaaaatctc
    44281 tttaaaccat gtcagcttta tctgcaatct caaagctgta ctttgatttt cattgagtac
    44341 tagaaggaaa tccttcaaat tacagatttc tttcaccgca ttttccattt tgtggtataa
    44401 tgaaaaatgt tgacaaatag tataataaaa acaaaggaga aaccgcatgc tgaaatggga
    44461 agacttgcct gtggaaatga aatcaagcga ggttgagttt tactaccagc ttgtctctaa
    44521 aaggaagggg tcgctgattt tcaagcgttg cttggccttg gttttggcct tggtcttact
    44581 ggttctgacc tctcccatct ttctcatctt gagcatttgg atcaagttgg atagcaaggg
    44641 gccagtgatt tacaagcaag agcgtgtgac ccagtacaac cgtcggttca agatttggaa
    44701 gttccgtacc atggtgatgg atgcggataa aaaaggaagt ctggtgactt ctgctaacga
    44761 tagccgcatt accaaggttg gaaatttcat ccgacgtgtt cgtttggacg aactgcctca
    44821 gttggtcaat gtccttaaag gtgagatgtc ctttgtcggt acacgacctg aagtgccacg
    44881 ttatacagag cagtacagcc ctgaaatgct ggcaaccttg ctcttgccag cagggattac
    44941 ctctccagcc agcatcaact acaaggatga ggacaccatc atcagtcaaa tgacggagaa
    45001 aggtctgtca gctgatcagg cctatgtgga gcatgttctt cctgaaaaga tgcgctataa
    45061 cctcgcctat ctccgagagt ttagtttcct tggggacatc aaaatcatgt ttcaaaccgt
    45121 gtttgaggta ctaaaataaa gtagtcataa gaaaatgagt acagataaaa ggagaaaagc
    45181 aatgccaaat tacaatattc cattttcacc gcctgatatc acagaagcag aaattgctga
    45241 agtagcggat accctgcgtt ctggttggat cacaacaggt cctaaaacaa aagaactgga
    45301 gcgccgcttg tctctttaca cacagacacc taagactgtc tgtctcaact ctgcgacagc
    45361 cgctctggag ttgattttac acgttttgga agtgggacct ggtgatgaag tcatcgttcc
    45421 agccatgacc tataccgctt catgtagtgt cataactcac gtgggagcaa ctcctgtcat
    45481 ggtggatatc caagcagata cgcttgagat ggactatgac ctgctggagc aagccatcac
    45541 tgaaaagaca aaggtgatta tcccagtaga gcttgcaggg attgtttgtg actatgaccg
    45601 tttgttccaa gttgtggaaa acaaacgtga cttgtttgtt gcttcaagca agtggcaaaa
    45661 agcctttaac cgtattgtaa ttgtctctga tagtgcccac gctttgggat ctacttataa
    45721 aggacaacct tctggttcta tcgctgactt tacttccttc tcattccacg ccgttaagaa
    45781 ctttacaacg gccgaaggtg gaagtgcgac ttggaaggcc aatccagcga ttgatgacga
    45841 agagatgtac aaggaattcc aaatcctttc ccttcacggg caaactgagg acgctcttgc
    45901 caagatgcaa ctggggtcat gggaatacga tatcgttaca ccagcctata agtgcaacat
    45961 gaccgatatc atggcttcac ttggtttggt acaattggac cgctatccaa gtttgttgca
    46021 acgccgtaag gacattgtgg accgctatga tagtggtttt gcaggttctc gcatccatcc
    46081 tttggcacac aagactgaaa ctgtcgaatc ttcacgccac ctctacatca cccgtgtaga
    46141 aggagcaagc ctagaagaac gcaacctcat catccaagaa ttggctaaag caggaattgc
    46201 aagtaatgtt cactacaaac cgcttcctct cttgacagcc tataagaatc ttggatttga
    46261 tatgacgaac tatcctaagg cctatgcctt ctttgagaat gaaattaccc tccctcttca
    46321 tactaaatta agcgatgaag aagtagacta tatcattgag actttcaaaa cagtttctga
    46381 aaaagtgcta actttatcaa aaaaatgaca aactacagtc aagcgaaagt gatcctgtcc
    46441 ctaaaaagtc taattgagtg taaaaactgt tgttttcaat tgataatagt ttacacctgt
    46501 agttgaggcc tctctctcct cagagagaga atttttatag gattttcctt tcttgtggga
    46561 gtcccgtggt ttgaaataag atgtgagcaa tttggtgtag catttagaat ccttactaga
    46621 catcatttag aaaatctagt gtcttgttct agtttttaat tcaccctatt ttttgaaaga
    46681 cgtgagtttc catgagtgag attgtggaaa ctcgcgtctt tttttgtttt cagaatattg
    46741 ttcaaagttt tgtgcctgtc tttcatgttc tagtcattct tttgcatgat agaatttata
    46801 gcatattgat attataataa tacaaatatt ctatatgttt agtgatgctt gctatacatc
    46861 attagatctc ccgcgagaca atctataaaa cacttgtcta cgattaccta tatgccctat
    46921 tccagtattt tagaagcact gcatctattt ttatcgaggt taaatctagc ttttatagaa
    46981 ggtctattta agaaatatat tgtagtgttt tagtttcaat ccgccatatg agcgatattc
    47041 aggtaaatat ccctggcaaa tgcttgtatg acaagatatt tgttctttca tttataattt
    47101 acaacatatc aacaaattta aatatagtaa atgggatatt ttatattcaa gctaagaaag
    47161 atagcatcac ttttgaatgg aaggctaaag agcaaactag gaagttggcc atagatagct
    47221 caaaaccctg ctttgaggtt gtagatatag taaaatgaaa taagaatagg acaaatcgat
    47281 cgggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact attatagttt
    47341 cagtctacta tagaactgac caagtcagta acctagactt agggcaaggc ggcactgacc
    47401 tagtttgaag agatttccga agagtataaa ttttaatatt ttcttgtgtt attccttgac
    47461 aattcaattt ggaaaatata tgataaagat aatgacagcg gtgtcattct atctgtttta
    47521 agaaaagtaa taatcaattg ttaaaaatag taaaaaaatt ggaggttctg atgaaatatt
    47581 ttgttcctaa tgaggtattc agtattcgta aattaaaggt ggggacttgc tcggtactat
    47641 tggcaatttc aattttggga agccaaggta ttttatcgga tgaagttgtt actagttctt
    47701 caccgatggc tacaaaagag tcttctaatg caattactaa tgatttagat aattcgttaa
    47761 gtgttaatag tatcagctct aatggtacta ttcgttccaa ttcacaatta gacaacagaa
    47821 cagttgaatc tacagtaaca tctactaatg aaaataagag ttataaggaa gatgttataa
    47881 gtgacagaat tatcaaaaaa gaatttgaag atactgcttt aagtgtaaaa gattatggtg
    47941 cggtaggtga tgggattcat gatgatcgac aagcaattca agatgcaata gatgctgcag
    48001 ctcaagggct aggtggagga aatgtatatt ttcctgaagg aacttattta gtaaaagaaa
    48061 ttgttttttt aaaaagtcat acacacttag aattgaatga gaaagctaca attctaaatg
    48121 gtataaatat taagaatcac ccttccattg tttttatgac aggtttattt acggatgatg
    48181 gtgcgcaagt agaatggggc ccaacagaag atattagtta ttctggtggt acgattgata
    48241 tgaacggtgc tttgaatgaa gaaggaacta aagcaaaaaa tctaccactt ataaattctt
    48301 caggtgcatt tgctattggg aattcaaata acgtaactat aaaaaatgta acattcaagg
    48361 atagttatca agggcatgct attcaaattg caggttcgaa aaatgtatta gttgataatt
    48421 ctcgttttct tgggcaagcc ttacccaaaa cgatgaagga tgggcaaatc ataagtaagg
    48481 agagcattca gattgaacca ttaactagaa aaggttttcc ttatgccttg aatgatgatg
    48541 ggaaaaaatc tgaaaatgtg actattcaaa attcctattt tggcaaaagt gataaatctg
    48601 gggaattagt aacagcaatt ggcacacact atcaaacatt gtcgacacag aacccctcta
    48661 atattaaaat tttaaataat cattttgaca acatgatgta tgcaggtgta cgttttacag
    48721 gattcactga tgtattaatc aaaggaaatc gctttgataa gaaagttaaa ggagagagtg
    48781 tacattatcg agaaagcgga gcagctttag taaatgctta tagctataaa aacactaaag
    48841 acctattaga tttaaataaa caggtggtta tcgcagaaaa tatatttaat attgccgatc
    48901 ctaaaacaaa agcgatacga gttgcaaaag atagtgcaga atatttagga aaagtatcag
    48961 atattactgt aacaaaaaat gtaattaata ataattctaa ggaaacagaa caaccaaata
    49021 ttgaattatt acgagttagt gataatttag tagtctcaga gaatagtata ttcgggggta
    49081 aagaaggaat tgttattgag gattcaaagg gtaaaataac cgttttaaat aaccaatttt
    49141 ataatttatc cggtaagtat atatcattca tcaaatctaa tgcaaatggg aaagaacctg
    49201 ttatacgtga tagcgatggt aatttcaata ttgtaacgga gaatgggctt tacaaaattg
    49261 taacaaataa tttaagtgat aaaaacgaaa aagaaaaaaa caaagaggaa aaacaatcta
    49321 attcaaataa tgtaattgat agtaaccaga agaacagaga gtttaactca agtaaagata
    49381 atagacaaat gaatgacaag atcgacaata aacaagataa taagacagaa gaagtaaact
    49441 ataaaatagt tggagatggc agagaaactg aaaatcatat taataaatct aaagaaatag
    49501 tagatgtaaa acaaaaatta ccaaagactg gttcgaacaa gattatggaa ctattcttaa
    49561 cagtgacagg aattggttta cttttgacac taaaagggtt gaagtattat ggtaaagata
    49621 aataaaattt gttcgataca aggaagttcc gtagaaaatg aggatattgt aggttcacaa
    49681 aatcagtatt tttggattat tggtggagct acagatttat ataattctaa agaggagata
    49741 ggttattcag tctcagaagt tgtacatatt ttatcagaaa gtttgtcggt taattgtaaa
    49801 gaatcaaaaa ctcttaaaca aatatttgaa actgctttac tcgaggttaa agatgaaatc
    49861 ggtttaaact catatgaatt aacagagtat agtaaaatga aataataata ggacaaatc
//
LOCUS       DAVHSL010000009        48735 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000009 DAVHSL010000000
VERSION     DAVHSL010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.009"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(382..1362)
                     /locus_tag="VVR39_000528"
     CDS             complement(382..1362)
                     /locus_tag="VVR39_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU6030069.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1679..3694)
                     /gene="recG"
                     /locus_tag="VVR39_000529"
     CDS             complement(1679..3694)
                     /gene="recG"
                     /locus_tag="VVR39_000529"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU6030070.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3713..4816)
                     /locus_tag="VVR39_000530"
     CDS             complement(3713..4816)
                     /locus_tag="VVR39_000530"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU6030071.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4806..5174)
                     /locus_tag="VVR39_000531"
     CDS             complement(4806..5174)
                     /locus_tag="VVR39_000531"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU6030072.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5213..6244)
                     /locus_tag="VVR39_000532"
     CDS             complement(5213..6244)
                     /locus_tag="VVR39_000532"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6030073.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6246..7277)
                     /locus_tag="VVR39_000533"
     CDS             complement(6246..7277)
                     /locus_tag="VVR39_000533"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6030074.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7358..9871)
                     /gene="secA"
                     /locus_tag="VVR39_000534"
     CDS             complement(7358..9871)
                     /gene="secA"
                     /locus_tag="VVR39_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU6030075.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10017..10304)
                     /locus_tag="VVR39_000535"
     CDS             complement(10017..10304)
                     /locus_tag="VVR39_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030076.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10315..10965)
                     /locus_tag="VVR39_000536"
     CDS             complement(10315..10965)
                     /locus_tag="VVR39_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6030077.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(10969..11610)
                     /locus_tag="VVR39_000537"
     CDS             complement(10969..11610)
                     /locus_tag="VVR39_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030078.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11603..12394)
                     /locus_tag="VVR39_000538"
     CDS             complement(11603..12394)
                     /locus_tag="VVR39_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030079.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLEKYEDNV"
     gene            complement(12579..12914)
                     /locus_tag="VVR39_000539"
     CDS             complement(12579..12914)
                     /locus_tag="VVR39_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030080.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYIPLY
                     ALFSLSWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13054..13389)
                     /locus_tag="VVR39_000540"
     CDS             complement(13054..13389)
                     /locus_tag="VVR39_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030081.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13480..14790)
                     /gene="der"
                     /locus_tag="VVR39_000541"
     CDS             complement(13480..14790)
                     /gene="der"
                     /locus_tag="VVR39_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU6030082.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14804..15517)
                     /locus_tag="VVR39_000542"
     CDS             complement(14804..15517)
                     /locus_tag="VVR39_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU6030083.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLKQKKLL"
     gene            complement(15514..16410)
                     /gene="dnaI"
                     /locus_tag="VVR39_000543"
     CDS             complement(15514..16410)
                     /gene="dnaI"
                     /locus_tag="VVR39_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU6030084.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16411..17580)
                     /locus_tag="VVR39_000544"
     CDS             complement(16411..17580)
                     /locus_tag="VVR39_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU6030085.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(17581..18054)
                     /gene="nrdR"
                     /locus_tag="VVR39_000545"
     CDS             complement(17581..18054)
                     /gene="nrdR"
                     /locus_tag="VVR39_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU6030086.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18194..18559
                     /locus_tag="VVR39_000546"
     CDS             18194..18559
                     /locus_tag="VVR39_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6030087.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18564..19259
                     /locus_tag="VVR39_000547"
     CDS             18564..19259
                     /locus_tag="VVR39_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030088.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19276..20043
                     /locus_tag="VVR39_000548"
     CDS             19276..20043
                     /locus_tag="VVR39_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030089.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYK
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20396..21595)
                     /locus_tag="VVR39_000549"
     CDS             complement(20396..21595)
                     /locus_tag="VVR39_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030090.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21592..22485)
                     /locus_tag="VVR39_000550"
     CDS             complement(21592..22485)
                     /locus_tag="VVR39_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030091.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22602..22682
                     /locus_tag="VVR39_000551"
                     /pseudo
     CDS             22602..22682
                     /locus_tag="VVR39_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            23167..23380
                     /locus_tag="VVR39_000552"
                     /pseudo
     CDS             23167..23380
                     /locus_tag="VVR39_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23795..24412
                     /locus_tag="VVR39_000553"
     CDS             23795..24412
                     /locus_tag="VVR39_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU6030092.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24732..25619)
                     /locus_tag="VVR39_000554"
     CDS             complement(24732..25619)
                     /locus_tag="VVR39_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6030093.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25768..27651)
                     /locus_tag="VVR39_000555"
     CDS             complement(25768..27651)
                     /locus_tag="VVR39_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6030094.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKAGDVLGTFDSNKIAAAGLDDTTMLIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            28028..29482
                     /locus_tag="VVR39_000556"
     CDS             28028..29482
                     /locus_tag="VVR39_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6030095.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDHFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29463..30428
                     /locus_tag="VVR39_000557"
     CDS             29463..30428
                     /locus_tag="VVR39_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6030096.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30464..31738)
                     /locus_tag="VVR39_000558"
     CDS             complement(30464..31738)
                     /locus_tag="VVR39_000558"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU6030097.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31738..32910)
                     /locus_tag="VVR39_000559"
     CDS             complement(31738..32910)
                     /locus_tag="VVR39_000559"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU6030098.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33041..33289)
                     /locus_tag="VVR39_000560"
     CDS             complement(33041..33289)
                     /locus_tag="VVR39_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030099.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33357..33980)
                     /locus_tag="VVR39_000561"
                     /pseudo
     CDS             complement(33357..33980)
                     /locus_tag="VVR39_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34042..34491)
                     /locus_tag="VVR39_000562"
     CDS             complement(34042..34491)
                     /locus_tag="VVR39_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6030100.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(34493..35251)
                     /locus_tag="VVR39_000563"
     CDS             complement(34493..35251)
                     /locus_tag="VVR39_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6030101.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35366..37345)
                     /gene="pknB"
                     /locus_tag="VVR39_000564"
     CDS             complement(35366..37345)
                     /gene="pknB"
                     /locus_tag="VVR39_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU6030102.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37342..38082)
                     /locus_tag="VVR39_000565"
     CDS             complement(37342..38082)
                     /locus_tag="VVR39_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU6030103.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(38097..39410)
                     /gene="rsmB"
                     /locus_tag="VVR39_000566"
     CDS             complement(38097..39410)
                     /gene="rsmB"
                     /locus_tag="VVR39_000566"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU6030104.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKVFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39403..40338)
                     /locus_tag="VVR39_000567"
     CDS             complement(39403..40338)
                     /locus_tag="VVR39_000567"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU6030105.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEDQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40351..42747)
                     /locus_tag="VVR39_000568"
     CDS             complement(40351..42747)
                     /locus_tag="VVR39_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU6030106.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKDVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(42813..43127)
                     /locus_tag="VVR39_000569"
     CDS             complement(42813..43127)
                     /locus_tag="VVR39_000569"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU6030107.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(43152..43778)
                     /gene="gmk"
                     /locus_tag="VVR39_000570"
     CDS             complement(43152..43778)
                     /gene="gmk"
                     /locus_tag="VVR39_000570"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU6030108.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(43908..45521)
                     /locus_tag="VVR39_000571"
     CDS             complement(43908..45521)
                     /locus_tag="VVR39_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU6030109.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSHEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(45865..48612)
                     /locus_tag="VVR39_000572"
     CDS             complement(45865..48612)
                     /locus_tag="VVR39_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU6030110.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQIINSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVQL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
BASE COUNT        14079 a        10879 c         9106 g        14671 t
ORIGIN      
        1 aaccatacct acggcaagac gaagctgacg tggtttaaag agatttttga aaagtattaa
       61 cacctacaga caagcctgac gatagcaaga actaccctac tcgataggta tcggcttttg
      121 ctttctgaaa aaaattattt taagcaattt gacaaatcta gcaacaaaaa attctataaa
      181 tataatagat tgaaactaga atagtacaca tttgcttcta aaacattgtt agaaatcgat
      241 ttgactgtcc tgatcaattt gtcctgttct tgtttcattt tactatattt ccatgataaa
      301 acgcatagta tcaagttttc ttaagcccct gatactatgc gtgtttgtaa tttttaagat
      361 tttgtgctta gagtcgactc cttattttaa atatttaaaa ggaatctcac ttccacagag
      421 ccagttgtag acttggtcat tgacaaatac attcatggct tcgtgagcat actcaggcat
      481 gatgcgatag gttttatcgc aggtcagacg attataaatc gcaaactggg taatgggata
      541 gcaaacatcg tcgtccaagc ccgtaatcat cttaacctca ccttggatac gatgggcaag
      601 atttttgaca tcgatatagg caagggtcgc catgatttcc tcctctgttt catggaaggg
      661 gtcgtgaaac ttgaaataac ggaaaagttc gtcgtaagcc tcgctagtat taccaatctc
      721 aatcacccgt ctgaagtctg acaagaaggg ataaatggca actgttttct gaattcgagg
      781 attgagcgct gctgcaacta gagctagagc ccctccttgt gaggcaccat agctagaaag
      841 acgcttctca tcaacctgag acagactagc aacaatttcg accaactggt aaatatccag
      901 ataaacatcc ttataaaaga ggtggtcccg accttccata gcaccacgga taatatgccc
      961 cttcacggta tttcctaaag gagaacgcaa gccgtcttgt gagtaacctg actggccccg
     1021 cacatccatg gaaacaacac cgtaaccagc tacggtgaag cccagcatgt cggcccagtc
     1081 ccagccacgt cccatataac catgaaaatg gaagattagt ggaaccttct cctcactctt
     1141 tggaagaaca atgcgtgcat agacctttcc ttccttgctt ccttcaaatg ttaactcata
     1201 gcacttgact tgaggaatgt ggaaatctct ttcctccaag tggtaggatg gaagcgtgga
     1261 aacatttttc acttccccat cccagaaagc atcaaagtct tccggaacct catcccttcc
     1321 tctataggtc ttaatttctt ctagcaaagc tggatttttc atagcatgct ccttttattt
     1381 tgtaatcgtt accacaactg tagcatatct atgtaatcaa tgcaagaaag aaggataaat
     1441 agaaagtgaa tttagattct ttacttttag gatgatgggc tgaaagtagt tttagaaacg
     1501 aaaaaagagc atttcgctct ctcttctgtt tatactagtt ttttgcttcc ttcttttgga
     1561 aagtggtttg gtaatttact ttaatcgtta ctgtcatatg agagtcctcg tttctttttg
     1621 atgactttag tataagagcc aaatctaaaa actagcttaa gttttcctta gagaaagctt
     1681 aatccagatg ttctttcttt tccagatgaa gggcaatcat gcgccactct ggatcttctt
     1741 gccaagcttc tatagaacta atgtagctag caacctttct tgcttcttct aaaatcggaa
     1801 aatcttcgat aatatcagcc acttggaact ctggaagtcc tgactgtctg gttccaaaaa
     1861 tctcaccaga accacgcatt ttcaaatctt cctccgcaag gacaaatcca ttggtcgttt
     1921 ctgtcatgat gcgcatgcgg tctttcccag aatccgtctt gggattggca acgagaacag
     1981 cgtaggactg cttgtccccc cgaccgacac gacctctaag ctggtgaagc tggctgagcc
     2041 cgaagcgatc ggcatccatg ataatcatga cagtcgcatt gggaacgttg accccaacct
     2101 caataaccgt cgtcgaaacc agaatatccg tctttctctc cttgaaatcc tgcatgatct
     2161 ggtctttttc gtcactcttc atcctaccat gtagaagagc cacctctgcc ttgcctgcaa
     2221 aatgagtcgt caactcctct gataaggcaa tggcattttt caaatctaga gcttctgatt
     2281 cttcaatcaa aggagagatg acataggctt gggaaccttt ttgaatttcc ccctctaacc
     2341 aagtcaagac ctgaggtagt tgctcatgtt tgatccagcg cgtcacaata ggcttccgac
     2401 ctgctggcat ctggtcgata atggaaacat ccatatctcc aaaggctgtg atggcaagcg
     2461 tccgtggaat gggagtcgcc gtcatcatga ggacatctgg attgtcacct ttttcccgta
     2521 aaatacgcct ttgccctaca ccaaaacggt gctgctcatc gataataatc aaaccaagac
     2581 gagcatactc caccccatct tgtatcagag cgtgagttcc gataatcaaa tcagcctcac
     2641 ccttggcaat ggtctccaag acctctctct tttctgcagc tttcaaggaa cctgtcaaga
     2701 gagccagttt caaattggga aaaaggttct gtaaactctc aaagtgttgc tctgcgagga
     2761 tttctgttgg taccattagg gcagcctgat aacctgctgt cactgccgca aacatggcca
     2821 agccagcgac taccgttttt ccgctcccca catctccttg taggagacga ttcatgtagt
     2881 ggtcggactt catatcagtt aaaatttcct gcaaactctt ttcctgagct tgggtcaggg
     2941 caaaaggaag acttgcttta actgctgtca ctttttcctg agaccaattc agaaccagac
     3001 cacttccctg aactctattt tcagacttga gcatctgcag ctgcatttgg aaataaaaga
     3061 gttcctcaaa cttgatacgg cgaagagcct gcttgtattc tgccaaatcc tttggaaaat
     3121 gcatagctcg gactgcctga caacgggaca tgagtttgta tttgtctagt aaagactggg
     3181 gcagattttc ttctatcaag aggtccagtc cctgatcaaa agccgtcttg atgaccttga
     3241 ccagactggc ctgactgatt ccctgagcca gacgatagac aggctggagg tcatcttcta
     3301 cctgagccag aaccttcatc ccagtcagac tagccttagc gcggtcccat tttccaaaga
     3361 cagcaagggt tgctcccaac tctattttat cagccagata gggctggtta aagaaattca
     3421 ccgcaaaaac gacctctccc tgcttgagac taaaacgcag gcgattgcgc ttgaaaccat
     3481 aatactggac actagcagga gtcactacct gaccagaaag aactgccttc tcaccgtctt
     3541 ccagctccag cacctgcttg gttttgaagt cttcataacg gaaaggaaag tagagcaaga
     3601 gatcttgcaa gttttcaatt cctagtttgg cgtatttttc tgctgacttt ggtcccacac
     3661 caggcaagac atgcaagggt tgatgtagat tcatgctcca ctcctttctt ttctaataat
     3721 attctctcgg aatacggtcg ctgaggaggc aaaccacctc atagttaatg gttacgcggt
     3781 aggtcgctac ctgagttgca gtgatttcct tatccccatt ggagccaatc aaggttacct
     3841 tggttccgag tgggtaaggc ttaggcaatc gaatagtgat ttggtccatc gaaaccctgc
     3901 cgacaattgg gcaagcttgg ccatctacca agacagagaa attttgcatg tctcttgtcc
     3961 atccatctgc atacccgatt ggcacggtcg cgatgacttg ctcgctatcc gcttgataag
     4021 ttgctccata gcccatgcaa gctccagctg gaactgtctt gacatgaacc agagcagact
     4081 ccaaggtcaa ggccggtatc aaatcataag gcaaatccaa gaccgctcca cttggattga
     4141 ggccatacat ggcatctccc atacgaaccg cattgaaaat agtctctaca tgccaaagag
     4201 tcgttgcaga attgctagca tgaaccagct ctggaacttc cttcatacta gctaaaatag
     4261 ttttaaaccg ttctaactgg gcattaaaat agtcatctga ttcctcatca gcagtagcaa
     4321 agtgggtaaa gattccttca acacaaacac cgtgttgttg gagcaaatct tgagcctgct
     4381 caacctcact tgcctctcta aaaccaatcc gtcccatccc tgaatcaatc ttgaggtgga
     4441 ctgtcaatcc agttaggtcc acttccttat ctaagagtgc ttgaatccac tccagtccag
     4501 ccactgtcaa ggtgaagtca tattctttag ctagagcaac agcttcgatt tcagaaactc
     4561 ctaaaatgag gattggcttg ctgagtccag cttgtctgag ttcaatggct tcatcgatat
     4621 tggaaacgca aaagccatca acatcatctt gaattgcctt ggcaacggca acagctccat
     4681 gaccataagc attggccttg accacagcca acttgagcgt tccttgaggg atatgagccc
     4741 ccatttgctg aatattttgt cgaatagctc ccagatgaat cagagccttg gttggtctat
     4801 gtggactagc tttcatgatt ttcctccaaa atgacactgg ctgtcacaaa ctgatcggtg
     4861 tggctgatag acagccaaat ctttcctgaa aatggtgcct gactaaaata aggcgcccca
     4921 cgttcattgt tcaagacttc caaatcctga aaaccgagct tgctaatgcc cgttcccata
     4981 gccttggaaa aggcctcctt agccgaccag cgaccagcta aatattctat ttgcctgcgt
     5041 cctttgagac tggtgaagcg ctccatttcc tgagcggtca gtacacgctt agcaaatcct
     5101 tcatgtcgtg taactgcgct ttctatcgaa gccaattctt cgatgtcaat tccgtgtcca
     5161 actatcattc tcatcaaaag gagttgagat tccccaactc catccttttc acttattttg
     5221 tcaaggtaac ataaatctct tctaccaagg cctctgtatt ttcccaacct aggcaagggt
     5281 cagtaataga gcaaccaaag acctctggtt ggttttgacg accatctgct aggtaagatt
     5341 caatcataaa tcctcgaacc gtctttttaa ttttctcatt ccaatcacga ttctgcaagg
     5401 tctggcgaac aattcgaatc tgctccatat attgcttgcc tgagttatca tggttggtgt
     5461 caatgaggat aaaaggattt tcaagtccca tggtttcata gcgttcaatg gcttggagta
     5521 ggttttcata gtagtaattc ggcatataat tgccatactc gttgactgct ccacggagga
     5581 taacatgggc caaaggatta cctgatgtct caacttcctg cccatgataa aggaaggttt
     5641 gcttgttttg agcagcatag atggcgttaa acataacacc caaatttcct gaggttggat
     5701 ttttcatccc tactggtgca tcaatcccag aagccacaaa gcggtgctct tggtcttcca
     5761 cagaacgagc tccaacggca tggtagctga ccaagtcatc caccaagatc agatttgacg
     5821 gataaagcat ctcatctgcc gttgtcaaac cagtctctgt aatcacgcgg tagtgcaact
     5881 ggcgcacagc ctgcaagccg ttaatcaggc ttggagcctt agaagtatct ggctggtgaa
     5941 ctaatccttt atagccgtct ccattggtac gaggcttagc agtatacacg cgcatgacca
     6001 tgaaaatctt atccgctacc ttcttttgca aggcggataa acggcgagca tattccaaga
     6061 ccgcctcttc attatcagaa gagcaaggac caatcaccaa gagaatacgg tcatcttccc
     6121 ctgaaataat atctgccaat tccctgtcac ggctttcctt gagtctcaag gcttccgcag
     6181 acaattgggt ttcagccttg atgacttcca tatcgatttc ttgacctttt tcaataaatg
     6241 ccatcttatt ctcctaacgt tttgtaaatt tctctgacaa gagcttctgt gttatcccaa
     6301 cccaggcaag ggtctgtgat agacttacca aatacttctg gctcattttg tcgaccatct
     6361 tccagataag actcaatcat aaaaccacga acgaactgct taattttttc attccaagca
     6421 cggttaatca aggtctggcg gacaattcgg atctgttcaa tatactgctt accagaattg
     6481 tcatgattgg tatcaatgat gataaaagga ttttccaaac ccattttctc atactgggca
     6541 atggtatcaa ttaaattgtc ataatagtag ttgggaatat tttttccata ctcattaaga
     6601 gcaccacgaa gaatagcgtg tgaaagcggg ttcccagttg tttctacttc ttttcctaag
     6661 aaaaggaaac tttgtttgtt ttgagcagca taaatcccat taaacatgac attgagattt
     6721 ccagaggttg gatttttaaa accagtagaa aatcctgccc cacttgccac aaagcggtgt
     6781 tgctggtctt caactgaacg ggcaccaact gccatgtaag aaatcaaatc atctacaagc
     6841 ggaaggtttt caggataaag catttcatca gcagttgtca tccctgtttc tgtgatgaca
     6901 cgatagtgaa gatggcgaac ggctttgatt ccattgataa gactaggcgc ttctgtcgcg
     6961 ttaggctggt gaatcaagcc cttatagcca tctccgttgg tacggggttt ggcagtataa
     7021 acacgcataa ccataaagat acgatctgcc acttcttctt gtaggactgc caaacgctta
     7081 gcgtattcaa ggacagcttc ttcgttgtca gatgagcatg gcccgattac caagagaatt
     7141 cgctggtctt ctccacgtat aatggcttct agctcttgat ctcgctgtga tttcctctcc
     7201 aaagcctgac cttctaattt tgacaaggca cgaacttctt ctatatttat tttagagctt
     7261 tttgctgtaa ataccataac tcatctcctt ataaagcaaa cggataccca gtaaaaattt
     7321 acttttcaca agatatccgc ctctaaacta tctcatttta ttgtctttta ccgtgacagt
     7381 ttttaaattt cttaccagaa ccacatgggc aaagttcatt gcgtccaatc tggctcaaat
     7441 ccaaatcttc tggcatactt gcttggtgag cagcgatatt gcgagtcgct gttgtactga
     7501 tatgacgttc tgcctgtggt ctttcttgtt catgaatttg tgctttcatc atcaagcgtg
     7561 tcacatcaaa ctcaatcgaa ccaatcatat cattaaacat acggaaacct tctgcctgat
     7621 actcaacaac agggttgttc tgagcatagc cacgaagtcc aaccgcgtta cgcaattgat
     7681 caagggcatc gatatgatct gtccacttgt tatccaccac tcgtagaatc aaaacttttt
     7741 ggaattcttt aactgcttct tcatcgcgta gttttgaaac ctgactatcg taaaccttca
     7801 aggcacgttg gaaaagctct tccttgatgg ccttatcaga caagcctgac aagtcttcca
     7861 tcgtaataga atcttcagga agcaagttgt acttagcgaa gttcaaaatt gcctctagtt
     7921 tctcatcttg tttagcacgc gcatgaccgt caacgacacg accaatcgtg cgtttgatca
     7981 ttgcctgaat ttcaggtgcc aagtcacggt ctgcagtaat gacatcataa cgttgagtat
     8041 agataatctc acgttgttca cgcatgacat cgtcgtattg aaggacttgt ttacgggtat
     8101 cgtagttatt tccttcgaca cgtttttgcg ctgcttcaac ctgacgcgtc aacatgcgag
     8161 actcaatcgc ctcttcagac atgttgagac gttcaaagat tcccttcaag cgttcagaac
     8221 caaaacgttt catcaaatca tcttcaagag ataggtagaa ttgtgactca cctggatctc
     8281 cttgacgacc tgaacgtcca cgaagctggt tatcgatacg acgactttca tgacgttctg
     8341 taccaataac acaaagtcct ccaagttcac gaacaccttc accaagcttg atgtcggtac
     8401 cacgacccgc catgttggtt gcgatggtaa cggcaccacg ttgaccagca ttcatgatga
     8461 tttgggcttc tctatagtgg tttttggcat tcaagacttc gtgaggaaca ccagctgcaa
     8521 ccaatttctt agaaatgtag tcactagttt caaccgctac tgtaccaacc aagacaggtt
     8581 gacccttttg gtaacgagcc ttaacgtctt cgacaaccgc tttaaactta gattcgatac
     8641 ttgcataaag aaggtctgag tggtcaatac gttgaacagg acggtttgtt gggattggaa
     8701 taacacgaat gttgtagatt tcacgaaatt cttcttcctc agtcttacct gtacccgtca
     8761 taccagacaa ttttttgtac atacggaaaa ggttttggta cgtgattgag gcagatgtct
     8821 tggtttcatc ctggattggc acaccttctt tggcttcaat agcttggtgc aatccatcag
     8881 aataacgacg accttccatg gtacgacctg taaattggtc gacaatcaag atttcttgct
     8941 cttcgctcac cacatagtca atatcgagaa gcatgatgta gttggcacga agggcgttat
     9001 cgataaagtg ggtcaaagcc acgttttcga tgtcatagag gttttcaagt ttgaagtagc
     9061 tttcagccct gtcaatccct gaatcagaca aaccaatagt cttagactgc acatcgatga
     9121 tgtagtcatc tttgttcaaa gattttacat agtggtctgc catgtgatac aactgactgg
     9181 tttcaaccgc attggcacct gatacaatca aaggtgtacg agcctcgtca atcaagatag
     9241 agtcaacctc atcgaccaag gcatagttaa gcggacgttg taccatgttt tcagcgcgaa
     9301 caaccatatt gtcacgaagg tagtcaaatc cgatttctga gttagttgag taagtaatat
     9361 cacactcata ggcttctttt ttctccattg gagatttggt agccaagtta atccctactg
     9421 acaaaccaag ccaagagtac aattcaccca tctcagtcgc gtcacgttct gacaagtatt
     9481 cattaaccgt aactacgtga acccctttac ctgaaagggc attgaggtat accggcatgg
     9541 tcgcagtcaa ggttttccct tcccctgtac gcatctctgg cacgtcacca tggtgaagaa
     9601 caatcccccc catgacctga accttataag ggaagagacc taggacacgt ttggcaccct
     9661 cacggacaac cgcaaatgct tcataaagca atgaatccag tgattctcca ttttgataac
     9721 gttctttaaa ttcaactgtt ttcgctttta attggtcatc agtcaaagca gccatttggt
     9781 cttcatattt gaaaaccttg tcagccatct tttccagacg acggatttct cctttatcat
     9841 tttcgataat tgtttttaaa atattagcca tgtttttcct tactttaaat tccgaatatt
     9901 ttagaatgtt cctttaattt tagcacaatt actgattatt ttcaaggaag aatccccatt
     9961 ttgaaaagga aaaagaggtt agttttcaag ctaacctctc cgacttttat gactgtttaa
    10021 ttgccaaaaa tcggcaaaat ggcaaatgtg ataaataagt taatccaaag agaaagacag
    10081 caaatcagtc caaaaacaaa gagactgact ttcttggaca gcaaggccat caaaatggac
    10141 agaattccaa aaactagcaa gactttctgt atgatgaaga tgtcaatcct tacccccaga
    10201 atcgctctat cccaagggat aaagaagaaa gacagccaga tcagcagaac taaaccaata
    10261 taaaccttgg aatagcgtgt aataaatgat tttagatgtg ccataagcca tctcctagga
    10321 ttgtatatcc tttacatatt gtatatgtcc attttcgaca actaatacat ctgtacaaag
    10381 gtctgaaata tcttccgata tgtgcgacgt caggataacc agaccatttt cttttttcag
    10441 gtaagataaa atgacctgtt tggttaacct cacacttttc tcatccaaag cattcatagg
    10501 ttcatcgaga aagagtatag aaggagagga aataaaggct tgaatcaagg ccattttttg
    10561 ctttgttccc aaggataaat gacggtattc aacatcttca aattcctgta aatcatagta
    10621 ttgaatccaa taggcaattc ttttttccgt aactttagat gaaaaatacc ttaacagttc
    10681 caaattttct ctcagggata aatgagataa aaactcgact ttttcaatta aaattcctgc
    10741 atcctgaata taatgatttt ttaccccgta aactttacca tcttgaagaa cttttccttt
    10801 gtcaagctta atataaccag caagtatctt taaaagaacc gtcttgccag atccattatc
    10861 acctttaagt ccataaattt ttcctgattg aaacaccaaa ttcaactgat ttaaaatagg
    10921 tcttttccca taaattttct gtccatttat aatttcaagt ctcatcgttt atcctttctt
    10981 aaatttctct tccaagcgac taagaatcaa cataactaat aagcttaaga gtactaaata
    11041 cactgttaca atatgatcca tcatccattc ttgtcccaca aatgccaaaa aatagagaaa
    11101 aaaagaaaaa ccagcgcccg cactaatcag tgctatcaga taagacagta gtaagtacaa
    11161 catcattaac tgagcaagta aaaagaaaag tgcgactgtt ttgaaatgaa ttcctagcgg
    11221 aagtaaacca agaaaccaga caaacaaatc ttgagtaaaa aatttagaaa tgacaaccaa
    11281 tcgtttcctt gtataatcga aaaaggagct tgattgatag cgaatcaagt gatggtaatg
    11341 gtctgccaaa tcactttcaa gtaaaatgac agagagccat cctaccatga aaagcgaaag
    11401 gtttaacaag agtttgggga tttctaaatt cgcttcagaa tagtcattat aggaaaaaat
    11461 tgaaatcaat tctctcttga aaaagataac agcatcctgc ttttgaaccg ctgttgacaa
    11521 tagatggttt atcaaaatca tcatcagaac tatacgaagt agtaaaacaa tctttctctt
    11581 tagccaaata ttgttaaaat tcttaaacat tatcttcata tttttcaagc accatataag
    11641 ggacaacata aaggatataa ggagtaaaga gtttcatcaa acttacatcc ccatagctag
    11701 cttgcatcaa actcgtcata ggaaccatat agtaaggcaa ggcactatag agcagcatag
    11761 aaccaagcca aagaaacatc aaataggtga ttgccgaacg agtcacattc cccacataat
    11821 caactatttg taaaaaatag attgcattga tgaaaatacc gattagtagg acacaagtaa
    11881 agaacaaata gctttttatc tctccatcta ggagtctttg taaaccactt ccatcagaaa
    11941 atagagaatt ccatccaaga ggagaaaaag tcccaaagaa ataggttaca attgcaatta
    12001 tcagcacagt cactaaatat atcaaacaag ggatacttgc aacttgcaaa gtcaactttc
    12061 tttttaaccc ttgataactc acttctcttc caatactcaa tcgtaaaact ttatttttca
    12121 gctcaatata ttgaaaacct agcaaaacaa tgatgattgg aataataaat gattgataaa
    12181 aacctagatt gaactggaga atacgaaaat ctaatgctga ttttaataag tcatttttaa
    12241 ttgcttgtcc atcgaattta gctagatcgg gcgcatgaat atcaaaaaag aaataagtca
    12301 tcaaaacatc acgataaacc aaagcaagaa aaagcaaagt aagcaagaca taaacaaatt
    12361 tatgccttgc caaagttaag agaggaatct tcataagcca cctcctacaa atagaaagta
    12421 atataatact caatgaaaat caaagagcaa actaggaaac tagccgcaag ttgctcaaag
    12481 cactgctttg aggttgtaga taagactgac gaagtcagtt acatatataa tccaaggcga
    12541 cgttgacgtg gtttgaagag attttcgaag agtataaatc aatgccttcc gcctttagac
    12601 ttccctagtt cccgtctcaa gtcaagcatt tttttgaaac agatatagtc taaccagtca
    12661 ctagcaaaag cgataagtag taataatagc caaatacccc ataacttgat atctgtcaaa
    12721 tttctcaaga cgatattgaa aaacagaact gaaaaaactg tccaagaaag gctaaaaaga
    12781 gcatagaggg ggatgtaaat ccagtaaaaa tagtaaaaaa ttgggaaaaa tttactttct
    12841 ctattatcct tgtcaatcca gctgaaaaag taaaaacagg gtaataagat tatcatttta
    12901 aacaagtgtt ccatcacaag cctccttttt taaattgttt tctttagttt cgttctatta
    12961 aatgttatta ccaatataaa ccttggaata gcgtgtaata aatgatttta gaggtaccat
    13021 aagccacctc ctacaaatag aaaccgatat aaatcaatgc cttccaccct tagacttccc
    13081 tagttcctgt ctcaagcgaa acatttcttt gaaacaggaa taagttaacc aattcatacc
    13141 aatagctagc agaataaaaa gaaaccaaat gccccataac ttgatatctg tcacatttct
    13201 caagacggta ttgaaaaaca gaactgaaac aactgtccaa gcaaggctaa aaagagaata
    13261 gaaggggatg taaatccagt aaaaataata aaaaattgga aaaaacttac tatttctgtt
    13321 ggccttttca atccagttat caaaataaaa gtacggtgct aaaagtaaga atttaaacaa
    13381 atgttccatc accgacatcc ccctccttct tttgatagcg ttttctatta ttttattata
    13441 tcaaaagaat ctggaaatgt cattccagat tctacttttt tatttacgct ttcttgctat
    13501 gagatgaatc ggtgttccct caaagacaaa ggccttgcgg atttgatttt ccaagaaacg
    13561 taggtaagaa aagtgcatga gttcttcttc gttgacaaag ataacaaagg ttggtggttt
    13621 ggttgccact tgggtcgcat agaaaatctt gagacgtttt cctttgtctg tcggtgttgg
    13681 gttgatggca atggcatcca tgatgacatc gttcaagaca gctgatggaa tacgtgtatt
    13741 ttgactttcg ctgatttgct taatcatccc aggaagtttg tggagacgtt gcttggttaa
    13801 agctgataca aagataatcg gtgcgtaagg caggtattgg aactgctcac ggatatcttc
    13861 ttcccagttt ttcatagtgt ggttatcttt ttcaagcgta tcccacttgt tgaccacgat
    13921 aatcatccct ttaccagctt catgagcaaa tccagcgata cgcttgtcgt attcacgaat
    13981 cccctcttcc gcattgatga ccattaagac cacatctgaa cggtcaatag cacgcatggc
    14041 acgcatgaca gagtacttct cagtattttc ataaacctta ccagacttac gcataccagc
    14101 cgtatcaatc atggtaaact cttgaccatc tgtatctgta aagtgggtat caatggcatc
    14161 acgagttgtt ccagcaacag gactggcaat gacacggtct tctcccaaga tagcattaat
    14221 caagcttgat tttccaacgt taggacgacc aatcaagcta aacttaatga catctggatt
    14281 ttcttcttca tattcatttg gaaggttttc cacaatcgca tctagtacat cccctgtacc
    14341 gattccatgg acagatgaga taggcagtgg ttcacccaaa ccgagagcat agaaatcata
    14401 gatatcattt ctcatctcag ggttgtccac cttgttgact gcgaggataa ctggtttgtg
    14461 ggtcttataa agcttacgag ctacgtattc gtctgcatca gtaattcctt ccttaccaga
    14521 cacgacaaaa acgataacat ctgcttcttc catggcaatt tctgcctggt gcttgatttg
    14581 ttccatgaaa ggagcatcga catcatcaat tcctcctgta tcaatcatac taaaagagcg
    14641 attgagccac tcacccgttg cataaatacg gtcacgtgtc actccttcga catcttctac
    14701 aatggagatt cgctcaccag cgatccgatt aaatagggtt gatttcccaa cattgggacg
    14761 tcctacaatg gcaatagttg gtagggccat aatttctcac tttctacaat aacttcttct
    14821 gtttaagatt ttttctagtt gagcttggtt ctgcttggcc aaactgttct gctagacgct
    14881 gactccagct tgtggtcgca cgcgctccag catagtcagc ctgaacacgg tcataagctt
    14941 ggattgcctc agttgactgt tcttggtatt cttcctcaaa gacaacattc tctagtggca
    15001 gtctcggttt catatcatga tgttgatttg gcacacccag tgccatccca aagacagaat
    15061 aggtgtagtc aggtaggtta aagagctctg ccacttcttc agacttgtat cgaaccaaac
    15121 cgataatcac accaccatag cccaagcttt cagctgccaa caaggcgttt tgtccagcaa
    15181 gagctgcatc gaccgaacta atcaagagac cttccacacc ttggggttgg aaggtgtcgg
    15241 tatgaagtcg ggctcccttt tctgctcggt tcaaatctcc gacaaagaga aggaaaacag
    15301 cagactggcg aatggcttct tgaggtacca attcatacaa ggcatctttc ttctcttgac
    15361 ttcgtaccac aatcacagag taggattgga aattcttcca agatgatgcc atctgggctg
    15421 ctgtcaaaat ctcatttaag tctacttggg gaatttcttg ctctttaaac ctgcgcactg
    15481 aagtatgagc cttcatcaat ttaatggttt ctgtcatcga cggtttactc cttctaaacg
    15541 agtctcctca gccaaataac ggatgcgttc catgacacgt ctggcttccc aggtttcgtc
    15601 atttccattt ttccctttag cgaaatgctt ctccaaatct tcaaagttga agttagaggt
    15661 gaaaaaggtc ggtaaatttt cctgcatccg atattggaga atgacctgca ggatttcatc
    15721 acgcacccaa gcggtggatt gctcggcacc aatatcatct aaaatcagga cttcagaaag
    15781 cttaatctca tccactaagg tcttaacatt gccatcaccg atagcatttt tgacatcaat
    15841 gacaaagcta ggatagtgga ggagagtgga tgatacacca cgtttttctg ataaatcatg
    15901 agctagggca gccaccatga aacttttacc cacaccaaag tctccatata agtaaagacc
    15961 tttcaaatta ttggggtaat cgttaacaaa ttctatcatt ctttttagaa cagttaagcg
    16021 ctgaacatca tcacgataaa catctaaaaa actgacattt ttcaggctag atggaaaatt
    16081 aattaagttg agacgtttct tgatagccgc ttctttttca gctgcgatta gttcaggagt
    16141 ttcttcataa gaaacatccg catagccatg gttcatgact aatataggct tgtagccttt
    16201 ggcaatataa tctgtatctc ctcggaggaa tttatctctc tcagtgatgt attggttaaa
    16261 cttggaaata ctacggttca actcgtcctg attgagggat tcttgctgga caaaggccgc
    16321 aacatcagga tccttcatga ttttctgaac taaatcttga tagtgaaaac gacttggttg
    16381 acgtttgagt acatctccga cactttccat ctaatcacct ccgttatcta attttgctaa
    16441 taattctagg gtttggcgtt ccatctcttc taattcctca gcggatgacg tatttttata
    16501 ttcaggatta ctccatttag gaatattggt ttttgctggg gcagtctgat tctgtttttg
    16561 tgtttttgtt ttctgccctc gctcacggat gcgcaagact gccttttctg ccgaatgaat
    16621 cttttgatag gcatagtcat tggctacctt catggcatat ttctcattga tatttgccga
    16681 atcgacctta ttaaaggtca ataaaagaat gatattgatg acttcgtcca gcaagcccaa
    16741 gccagccatc tgttgcaaga gttctctttc tgtttgggta atggttccct tgcgtgtttg
    16801 cttgatttct gccaagaact gcagggcagt tttacttttg gcttctttga taatggttgt
    16861 ttccttaaga ctaaagtcag aggaaactgg tttttgagca attttttcac gcatgcgttt
    16921 ggttgaaata acctgagaaa cagctgttga cttggccaat tgataggttt caaaccaagt
    16981 ccatttcttc tcctcggcaa tagcaaagag gtttaagaca tcggactgct catccgcaaa
    17041 acgaagtcca tctcgagcca tcagctggcg aaaatgttcc aagtcaaaat cattggccac
    17101 tttcttcttg agaccaaggt cttcttgact gcctagttct gccaattctg gaaagacttg
    17161 attgagtgag acaggtattt cttcaccatc agcactttca actttcaaat cctccacagc
    17221 agagtcgcca atctttttct ctaagagtct gcgataaaca ggatgctcca agaagtcttg
    17281 actagataga ggagcatgga gggctagctg ataaacatcc cccttttgat agagggtcaa
    17341 gagattaaaa gcagataaga ttttcaatga ttttatcagt ctatccatcc caaagttgag
    17401 atgattgagg atacttgaaa aaagatattc ctttctacca ttatcccaaa aactgattgt
    17461 ataaagataa aggctcagtg cctcctgacc gataatcggg aggtagcact gtaccagaga
    17521 tgaggtatct tgcgacaccc gattattctt tagataagaa aaacggtcaa ttggcttcat
    17581 ttatctttcc tttttctttt tagaggactg ggtgatttgt tggagcaagc tctctaactc
    17641 actgacatcc ttaaaactac gatagacact agcaaaacgt acataggtaa tctcgtccaa
    17701 ttcagccaac tcctccatga caagtgaacc aatgtcctca ctttgaattt cattttcatt
    17761 tcgaccacgg agtttctgtt cgatacgatt gactaccatg ttgatttcat cacttgacac
    17821 aggacgtttc tgggctgagc ggataatccc attaaagatt ttatctctgg agaattgttc
    17881 ccgtgtgcca tcttttttaa caaccactaa ggttctttct tctactcgtt cgtaggttgt
    17941 aaaacggtgt tggcactcgt cgcactctcg tcttctacga atggtgttcc cttcttctgc
    18001 ttggcgacta tcgataacac ttgacttggt agccccacat tttggacaac gcatcctttc
    18061 cctccttatc gttttctttt cattatacca ttttttaagc gattcccaaa acaattcttc
    18121 tttttgcttg acaagttttt tgttttgttg tattatttaa ttaagacaaa aggataagag
    18181 aaaggagact aagatgtcct ggacatttga caacaaaaaa cccatctatt tacagattat
    18241 ggagaaaatc aagcttcaga ttgtttccca tacactggaa cccaatcaac aacttccaac
    18301 cgtgagggag ctagctagcg aggctggtgt caatcccaat accatccaaa gagccttatc
    18361 agaccttgaa cgagaaggat ttgtctacag caagcgaaca actggacgat ttgtgactaa
    18421 ggataaggag ctaatcgctc agtcacgcaa acaattatca gaagaagaat tggaacactt
    18481 cgtttcctcc atgacccatt ttggctatga aaaagaagaa ctaccaggcg tagtcagtga
    18541 ttatattaaa ggagtttaag cctatgtcat tactagcatt tgaaaatgta tccaaatcat
    18601 atggagcaac accagccctt gaaaatgttt ctcttgacat tccagctgga aaaattgtcg
    18661 gccttcttgg gccaaacggc tcaggaaaaa caaccctgat taaactaatt aatggcctct
    18721 tacaaccaga tcaaggacgt gtcctcatca acgacatgga cccaagccca gcaaccaagg
    18781 ccgttgtagc ttatttgcct gatacgacct atctcaatga gcaaatgaag gtcaaagaag
    18841 ccctaaccta cttcaagacc ttctataaag atttcaatct tgaacgcgct catcatctac
    18901 ttgcagacct gggcattgat gaaaatagtc gtctcaagaa actatcaaaa ggaaacaaag
    18961 aaaaggttca actgattttg gttatgagcc gtgatgctcg tctctatgtt ttggatgaac
    19021 ccattggtgg ggtggatcca gcagcccgtg cttatatcct caataccatt atcaacaact
    19081 actcaccaac ttctaccgtt ttgatttcta cccacttgat ttctgatatc gagccaatct
    19141 tggatgaaat tgtcttccta aaagacggaa aagtcgtccg tcaaggaaat gtagatgata
    19201 ttcgctacga gtcaggtgaa tccattgacc aactcttccg tcaggaattt aaggcctaag
    19261 caaaggagat tatttatgtt ttggaattta gttcactacg aatttaaaaa tgttaacaag
    19321 tggtatttag ccctctacgc agccgtgcta gtcctttctg ccctcatcgg aatacagaca
    19381 caaggcttta aaaatctacc ttacaaagaa agtcaggcta ctatgctact ttttctagct
    19441 acagtctttg gtggcttgat gcttacactt gcgatttcaa ccattttctt gattattaaa
    19501 cgcttcaaag gtagtgtcta cgaccgacaa ggctatctga ctttgacctt gccagtttct
    19561 gaacaccata tcatcacagc caaactaatc ggtgccttta tctggtcatt gattagcacc
    19621 gctgtattgg ctctaagtgc tgttattatt ctggctttaa cagctccaga atggattcct
    19681 ctttcttatg tgattacatt tgtagaaaca catctccctc agatctttct tacaggtata
    19741 tccttcctac taaatactat ttcaggaatc ctctgcatct acctggctat ttccattgga
    19801 cagcttttca atgaataccg tacagcactc gctgttgcag tctacattgg tatccaaatc
    19861 gtcattggat ttattgaact tttcttcaat cttagttcta atttctatgt caattcactg
    19921 gtaggactca atgaccattt ctatatggga gcaggtatag ccattgttga agaactcata
    19981 ttcatagcta tcttttatct cggaacctac tacatcttga gaaataaggt taatttgctt
    20041 taaataattt ttacctagat atgtaacata ctcatagaac aaaagagacc aggcaaaaag
    20101 tctttacaat tagaaaacgc atagtatcaa gtgttaaaaa tccttgatat tatgcgtttt
    20161 ttgtgagctg acttatttcc tttcactata tcgcaaaatg aaataagaac ggaacgatgg
    20221 gattttggaa ttcaaatcaa tttataagaa tgttttagaa gtaatattat cctattccag
    20281 attcagttca ctatacaatt gagttttcaa gcaacctgtt tacataatgt gtacataatt
    20341 aggttcgtga ttccaccctt ttcaccttta aaaacctcgc tttcgcaagg ctcttctatt
    20401 tataagataa ggcacgttta aaggttttcc aaatccctaa atcatccgtt tgaagaacga
    20461 gactagcata catgcgtccg ataaatcctg ttgctaccac cgcaaaaatc actgtaatag
    20521 caagtgaaat ccatgcttcc gctccctccg catagccatt aatcgttcga aacggcataa
    20581 agaaggtcga aataaaggga atataagaac caatcttcaa gaggagattg tcaccagctg
    20641 cacctagagc tgtcactcca aaaaaaccac ccataatcaa aatcatcaaa ggcgacaagg
    20701 ctttccctga gtcttcagga cgagaaacca tagatcctag gaaggctgcc aagactacgt
    20761 acatgaaaag actgatcaaa ataaagagca aggtattcag tgagatagca tctcccaagt
    20821 gatccaaaat accagactga gccaagaatg gcaaatcttt aaagagcaaa acggcagcca
    20881 gaccacctac aacatagatc ccaatatgcg ttaaaatcac tagaaacaga gccatcatcc
    20941 gcgcatagaa atagtgactt gcccttatgc tagaaaagac gacttccata attttggtgc
    21001 ctttttcact ggcaacttcc tgagctgtta cacccgcata ggtaatcaga atcatataaa
    21061 gaaagaatcc taaggcacct gctgcaattg tttgaataaa ctttttattt tccttggctt
    21121 catcaatctt ttctgtgaat tgaattgtct gcgctaagcg tttttcctgc tcttgagaca
    21181 aggaagcagt tgaacgatta agctgatttt gcagttcatt gagtgtacct gtaacctcaa
    21241 atttaattcc attttcaagc gatgtttcgc catgataaac tgcctttaga acactatctt
    21301 cttgatcaat ggtcaaataa ccttttaatt tttcttcttt aattgcttct ttggcacttg
    21361 cttcgtcttt atagtcgaag ttaacaccat ttacattctt cagtccttct gctacagatg
    21421 gcactgttgt cactactgcc actttattat ttttagccat agaagaacct tggagatgcc
    21481 caattcctac agagattcct aaaaagagga acggcgaaat caccataaag aagaaactcc
    21541 atgactcgac atgtcgaaga taggtttcct tgattacaac ccacatattt ctcatacttc
    21601 cactcctgat tctagtttaa agatttcatc gatagttggc gcttgttggt caaatgttgc
    21661 gatatattga ccttgagtca agattgggaa gagttccctt ccagcgctct catcctccaa
    21721 aatcaatttc caactgcctt gtttggtcaa gctcacctgt ttgacatgag gaagattttc
    21781 caattcttcc ttgcttcgtt cacttgaaac aaagagacgc gttttcccgt attgattgcg
    21841 gacatcctga actggtccgt gcaagaccac acggccatct cgaatcatca gaatatcgtc
    21901 acaaagttcc tcaacattgg tcatgacatg gtcagaaaag ataatggttg ctccgcgctc
    21961 tttttcctga aaaatgactt gtttgagcaa ttctgtatta actgggtcca atccactaaa
    22021 aggctcatcc aagataatca ggtctggttc atgaatcaga gtaataatga gctgaatctt
    22081 ctgctgattt ccttttgaca gactcttgat tttatctgtc agctttcctt ttacttccaa
    22141 cctcttcatc cattgaggga gtttttcttt gacttctttg gcatccatgc cttttagagt
    22201 cgccaagtag cgaacttgtt caagaactgt caatttaggc atgagactgc gttcttcagg
    22261 cagataacca atccgagcat agatctcctg acgaatatcc tgaccatcca gaccgatttc
    22321 tccctgatat tctaggaatt ttaaaatact atggaaaatc gttgtttttc cagcaccatt
    22381 ttttccgact agtcccaaaa tacgacctgg tcgcgcttga aagtcaatac caaacaaaac
    22441 ttgcttggat ccaaaacttt tctctagact tcttacttct agcatctttc acctccgaaa
    22501 tttcttgcac tcattatact cctttttgat agcctttaca atgttttttg tccattttta
    22561 gaagactatt gctgtgtaaa atatggcctg gagcactttt atactcaatg aaaatcaaag
    22621 agcaaactag gaagctagcc gtagactgct caaagtacag ctttgaggtt gcagataaaa
    22681 ctgacgaagt cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagta
    22741 actatacgta cggcaaggcg aagctgacgt ggtttgaaga gattttcgaa gagtattagt
    22801 gataaatcca ttatacagca gcaaacttaa tttatacctt ccgctcctca actgtctatt
    22861 tttaatcctg aattgttatt tgagtaagtc ctttttcctc ataaagtttt cttcctctaa
    22921 aacttctgga aaaaagcgaa tagtttcaga caacattttt ataagaaaca agttcatctg
    22981 tcatttcaag aaggagtaat cctttatcta ctaatggacg gaacggaatt caaccgcttg
    23041 tccgatatgt tttctaagga ttatatagta aaatgaaata aaaacaggac aaatagatcg
    23101 ggacagtcaa atcgatttct aacaatgttt tagaagtaga tgcgtactat tctagtttca
    23161 atctattata tctattatgc acaccactat aggatctaat aaaaatcaca acaagttcat
    23221 tcatagatgg ttacctcagg gaactaagaa aacgactaca aaggaagtcg cattcatcga
    23281 aaagtggatt aacaactatc ctaaaaaatg cttgaactac aagtccccca gagaagactt
    23341 ctggatgact aacttgaact tgaaatttag caataattaa ttcaccatct aactatattt
    23401 agtaattatt tcagaactga ttaatattaa aattaactaa caattcaaag gattcatact
    23461 agccataaat tacgtccatc agagagagac tcttactact tttagatttt agtctttcta
    23521 gcttcagaat acatctaaac tttagggaaa atgactattc gaaagcgcga atgcctcaaa
    23581 attatctcag ataagctatt cgaaacttag aatgctttta aatttatgga attgcgatta
    23641 ttcgaaacct agaatgcata taacctttag ttgacagacc cattctaagt ctcgaagggc
    23701 tattcacttt ctattcctta tcaaaaaaga ctcattcccc ctttctcctc caaaatatgg
    23761 tatagtagaa atatactatc tatgaggagt ttacatgtca caggataaac aaatgaaagc
    23821 tgtttctccc cttctgcagc gagttatcaa tatctcatcg attgtcggtg gggttgggag
    23881 tttgattttc tgtatttggg cttatcaggc tgggatttta caatccaagg aaaccctctc
    23941 tgcctttatc cagcaggcag gcatctgggg tccacctctc tttatctttt tacagatttt
    24001 acagactgtc gtccctatca ttccaggggc cttgacctcg gtggctgggg tctttatcta
    24061 cgggcacatc atcgggacta tctacaacta tatcggcatc gtgattggct gtgccattat
    24121 cttttatcta gtgcgcctat acggagctgc ctttgtccag tctgtcgtca gcaagcgcac
    24181 ctacgacaag tacatcggct ggctagataa gggcaatcgt tttgaccgct tctttatttt
    24241 tatgatgatt tggcccatta gcccagctga ctttctctgt atgctggctg ccctgaccaa
    24301 gatgagtttc aagcgctaca tgaccatcat cattctgacc aaacccttta ccctcgtggt
    24361 ttatacctac ggtctgacct atattattga ctttttctgg caaatgcttt gacacgtaaa
    24421 aaatccgttt ggtttcccaa gtggattttt aaagcgtaga ttaactatag cttgatacta
    24481 aatatacttt ggtatggaaa tcatgcatat ttttcgatag tgaggcgagg acttacctag
    24541 cctttccgcc gtgatagaaa cacctgaaat ctaatggttt caggtattcg gaaactttga
    24601 gcctagtgtc tcaaagttta ggtatggaat ttcgaagaaa gtcgctaccg tccgtaatca
    24661 cttaaggaaa ggctcaaaaa tattgttttc aaccacaaaa tccgtttggt ttcccaagcg
    24721 gattttgtgc tttattttga aacttctttt gcaagaacaa agttcccaag tgtggcagaa
    24781 ccatttcctg cgactgctgg cgtcacgata tagtcacgca catctggtac tggtaggtaa
    24841 ccattaagaa gagatgtaaa tttctcacgg acacggtcca gcatatgttg ttgagccatg
    24901 acccctccac caaagacaat cacgtctggg cggaaagtca ctgtcgcatt aaccgcagct
    24961 tgagcgatat agtaggcttg aacatcccaa acagggttgt tgagttcaat agtttcccca
    25021 cgtacacctg tacgagcttc caaacttgga ccagctgcat aaccttctag acatccctta
    25081 tggaaaggac aaacaccctt aaactctttt tcaatatcca ttgggtgtct agcaacataa
    25141 taatgaccca tttcagggtg acccacacca ccgataaact caccacgttg gatgacgcct
    25201 gcaccgatac ctgtaccgat tgtgtagtaa accaagtttt cgatacgacc accagcattg
    25261 ttacgggcaa ccatttcacc gtaagcagag ctgtttacgt ctgttgtgaa gtacattggc
    25321 acgtttaggg cgcgacgaag ggcaccaagc aagtctacat ttgcccagtt tggttttgga
    25381 gtcgtcgtga taaagccata agtttttgag tttttgtcaa tatcaatcgg cccaaatgaa
    25441 ccaactgcaa gaccagcaag gttatcgaat tttgagaaga actcaatggt tttatcgatt
    25501 gtttcgattg gagttgttgt tggaaattgt gttttttcta caacgttaaa gttttcatca
    25561 ccgacagcac agacaaactt tgtaccgccc gcttccaagc ttccatataa ttttgtcatg
    25621 ataaacctct tgtttttatt ttctttatta tagcatactt cgaaagtcta aatgtctcta
    25681 ttttttagat tttcctctgt aaatcttact atctaataaa aacgaacaaa catgtcattt
    25741 gttcgttttc acattagaga ggattgatta gattttcact tcgatcacag catccccctt
    25801 cgcaactgaa cctgttgcga ctggagctac tgaagcgtag tcacctgtat ttgtaacgat
    25861 aagcattgtc gtatcatcaa gtccagctgc agcgattttg tttgagtcaa atgttcccag
    25921 aacatcgcca gctttcacct tatcaccttg agcaactttt gcttcaaaac cgtcaccgtt
    25981 catagataca gtgtcaatac caacgtgaat caaaacttca gcaccatttc ttgttttcaa
    26041 accaaaagcg tgccctgttg gaaaggcaat tgaaacttca gcatcagctg gtgcatagac
    26101 cacgccttgg cttggtttca cagcgatacc ttgtcccata gctccacttg agaagactgg
    26161 gtcattgaca tcagcaagag cgacaacatc accgacgata ggagttacaa gtgtttcatt
    26221 ttgaagagct gctggcgcaa cttcttcttt ttcttcagcc acttcagctt gttttgcagc
    26281 tgcagttgcg tctacttcat cttcgtaacc aaacatgtaa gtaagagcaa aaccaagggc
    26341 aaatgatacg gctaccataa gaaggtattg tggaagttgt ccgttaccaa cataaagcat
    26401 tgtaccaggg atgatggtga taccattacc agtaccagca agtccaagga tagaagccaa
    26461 tccaccaccg attgcaccag caatcaatga aaggaagaat ggtttacgga agcgcaagtt
    26521 caccccgaag atagcaggct ctgtaatacc taggaaggca gaaagagcag ccgggaaagc
    26581 aagtgttttc agttttggat tttttgtttt aacaccaacc gcaacagtag cagcaccttg
    26641 agctgtcata gcagctgtga tgatagcgtt gaatgggtta gcatggtcag cagcaagtaa
    26701 ttgcacttca agcaagttga agatgtgatg cacacctgac acgacgatca attggtgaac
    26761 cccaccaatc aagaaaccac caagaccaaa tggcatgcta agaatcgctt ttgtagcaat
    26821 aaggatgtag ttttcaacaa cgtggaaaac tggtccaatg acaaagagtc caaggataga
    26881 catgaccaaa agtgtcacga atggtgttac caagaggtca atgacatctg gaacaacctt
    26941 gcggacagct ttttcaaatt tagctccgac aaccccgatg atgaaggctg gaagaacgga
    27001 accttgcaaa ccaacaacag ggatgaaacc aaagaagttc atcgctgtta cttcaccacc
    27061 ttgagcaact gcccaagcgt ttggaagtga gccagagaca agcatcatac caagaacgat
    27121 accaacggca ggatttccac caaatacacg gaaggttgac cacacaacca aacctggcaa
    27181 gatgatgaag gctgtatctg tcaagatttg tgtgtaagtt gcaaagtcac ctggaagtgg
    27241 catttcaaga gcgttgaaaa gaccacgcac acccatgaag agacctgtcg ctacgataac
    27301 tgggatgatt ggaacgaaaa catcaccgaa agtacggata gcacgttgga accagttccc
    27361 ctgtttagca acttctgctt tcatgtcatc cttagatgat gttggtaagc caagtacaac
    27421 aacttcatcg tacattttgt taactgtacc tgtaccaaag ataatttggt attgccctga
    27481 gttaaagaaa gcaccttgaa ctttttccaa gttctcaatc acttctttat tgattttctc
    27541 ttcatctttg accatgacac gtaaacgagt cgcacagtgg gcaacactat tgacattttc
    27601 acgtccgccc aaggcatcga tgactttttt tgcaatttcc tgattgttca tttgcaaaaa
    27661 tctccttata taacattttg ttcttgtttg aaagcgattt tattcgccct tacgactatt
    27721 attttatcat gttttaaaaa tatgtcaagc gttttgcata aaaaatattc tatctactta
    27781 gtgggcaagc tttagattga ttgtttttga ctgtttcatc aggaatttct tgaaaaataa
    27841 gtttgaaacc ttggttaaaa agtcttttat ttcattatct ttcacatttt cgtaaaaatt
    27901 tgattgattt cctgtattta ttttatgata atcgtttgac agttttttct cttttttaat
    27961 ataaaaggct tgcatttttt atcgaaaaca gttactatta aaagtgataa gatttttgga
    28021 ggaatgaatg gaatggacaa ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga
    28081 agaaattcaa catataaagg aaaatatggc acaatctcca tggcatactc attaccatgt
    28141 tgagccaaaa acaggacttc tcaacgaccc aaatggcttt tcttactttg atggcaagtg
    28201 gatcctcttt taccagaatt ttccttttgg tgcagcccac ggtttgaaat cttgggcaca
    28261 gctagaaagt gatgatttgg ttcactttag agaaactgga atcaaagttt taccagatac
    28321 tccattagat agccacggtg cctactctgg ttctgccatg caatttggcg ataacttatt
    28381 cctattttat acaggaaatg ttcgcgatga aaactggatc cgtcacccat accagatcgg
    28441 tgctttgatg gacaaggagg gtaagattac aaagattgac aagatcttga ttgaccagcc
    28501 agcagactct actgaccact tccgcgatcc acaaattttt aactttaaag gtcaatacta
    28561 tgctgtcgtc ggtggacagg acttggagaa aaaaggcttc gtccgtctct acaaggctgt
    28621 caataacgac tacacaaact ggcaagcagt tggcgacctt gactttgcta acgaccgtac
    28681 tgcctacatg atggaatgtc ctaatctggt ctttgtagag gaacatcctg tccttctcta
    28741 ctgtccacaa ggattggata agaaagttct agactacgat aatatctttc caaatatgta
    28801 taagattggg gcttcctttg accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca
    28861 aaacatggat tacggtttcg aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg
    28921 tgctctagca gttagctggc ttggtttgcc agatgtttct tacccatctg accattttga
    28981 ccaccaagga accttctctt tggtcaagga actcactatc aaagacgaca agctctacca
    29041 gtatccagtc gctgctatta aggaccttcg tgcttctgaa gaagccttct caaaccgttc
    29101 ccaaaccaag aacacttacg aacttgaact caacttggaa gctaatagcc agagcgagat
    29161 tgtcttactt gctgataaag aaggtaaggg actttcaatc aactttgacc ttgtaaacgg
    29221 tcaagtgaca gtggatcgta gccaggctgg agagcagtat gcccaagaat ttgggacaac
    29281 tcgttcttgc cctatcgaga atcaggctac tactgctaca atcttcatcg ataactctgt
    29341 ctttgaaatt ttcatcaata aaggagaaaa agtattttct ggtcgtgtct tcccacatgc
    29401 ggaccaaaat ggtatcctga tcaaatctgg aaacccaact ggaacttact atgaattaga
    29461 ttatggtcgc aaaactaact gatgtcgcca aacttgcagg cgtcagtcct actaccgttt
    29521 ctcgggttat caataaaaaa ggatatctat ctgagaaaac catccaaaaa gtcaatgaag
    29581 ccatgcgaga attgggctat aaacccaaca acctggctcg tagtctgcaa ggaaaatcag
    29641 ctaagttaat cggcttgatt ttccccaata tttccaatgt tttctatgca gaattgattg
    29701 ataaattgga acatcaactc ttcaaaaatg gttacaagac catcatctgc aacagtgaac
    29761 atgattctga gaaggaacgc gaatacatcg aaatgttgga agccaatcag gtggacggca
    29821 tcatttctgg tagtcacaac ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta
    29881 tttcctttga tcgaaaccta tcgccagaca tccctgtcgt ctcctctgac aactatgctg
    29941 gtggggttct tgctgcccaa accttggtca agacaggtgc ccagtctatc atcatgatta
    30001 cagggaatga caattccaat tcgccaaccg gactgcgcca cgctggtttt gcatccgtac
    30061 tcccaaaagc tcctattatc aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg
    30121 aaatcaagaa tatcttgacc cgggaaaaac cagatgccat ttttgcttcg gatgatttga
    30181 cagctattct ggtcattaaa atcgctcaag aattgggcat ttctgtccca aaagagctca
    30241 aggtcatcgg ctatgatggg acctacttta tcgaaaatta ctaccctcaa ttggctacta
    30301 tcaagcaacc tttggaagag attgcttgtc tcactattga tcttctcttg caaaagattg
    30361 aaggcaagga agtcgccaca actggttact tcttaccagt tacactatta ccaggaaaaa
    30421 gtatttaaac acaagaaaac tcagaccgat tcgtctgagt tttttatgat cttaaatttt
    30481 cgagatagcg ctgggctgtc tctaggttaa aggttttatc tgagatgagg cgctctacta
    30541 ggggagcaac ttcagattca ctagccccag ctaggagagc tagggatttg gcctgtagtt
    30601 tcatgtggcc ttgctggatg cccgtactta ccaaggcttt gagggctgca aaattttggg
    30661 caagaccgat ggacacgata atctgggcta attctctggc agaaggattt cctagtagat
    30721 catgactgag agctacacgt gggttgaggc cgatagagcc acccttagtc gctacaggca
    30781 tgggcagggt catctcaccg accaattctt ctctttcaag gtccagcgtc cagcagctaa
    30841 gaccttgata gcgtccatct cgactggcaa aggcatgggc cccagcttcg atggcacgcc
    30901 agtcattacc agtggcaatc aaaatcgcat caataccatt aaaaattcct ttattatgag
    30961 tagcagctcg gtaaggatca gcctgcgcaa actgactagc caacgcaatt ttctccgcaa
    31021 tctctcgtcc ttgatccttt tggcggctca agtagcgaaa ggcgatgcga cagcttgcag
    31081 tcaccagaga atcggtcgcg tagttggaca ggattgccat gagactctgt ccctgactga
    31141 gttcttctaa gactggtttc aaggcttcca gcatggtgtt gagcatattg gcacccatgg
    31201 cttcctgggt atcgacatga atataaacaa cgagaaagtc tggttcacct tttatctgct
    31261 cgacatgcag atcacgcgcc ccacctccac gtttaacgat agaaggatag gcttgattgg
    31321 caagctccaa gagctccgct ttcttgctgg caatcttctc ttgcgctagt ttaggattag
    31381 caacttgata aagggctacc tgcccaatca tctgtcgctg atggacttgt gcagtaaaac
    31441 cacctgcacg cttgatgatt ttgctggcat agctggccgc cgcaaccaca gagggttctt
    31501 ctgtcacata gggaacggtg tattcctgac cgttgacaag tacctccgga accagtgaat
    31561 aaggcagaga aaaagttccc actacattct cactcagctg gtctgccaca gtcacgctca
    31621 tctgttcatc cttctccaga ctagcttgtc tctcaggact aaggagcgcc tgagctttta
    31681 acagctcgag gcgctcttgg tatgattttt tagaaaatcc attccaactt atcttcatta
    31741 tttttcaacc ttgctataac ggcgttggtg gtcgagaatt tcaaccaagg caaaatcttg
    31801 attttcatag ccagcaaact gggcagagtt tgtttcatcc aagtttactt cctcaaaaaa
    31861 gaccttttca tagtctgcaa cggatagggc agttcgttgg ttgagcttgt tcaagcggtc
    31921 tttatccaaa taagcttcat atccttcaac caattcacca ctgaagaact cagccacagc
    31981 tccacttccg taactataaa gggcgatttt atccccagct ttcaagctat ctgtattttc
    32041 caagagagac aaaagtccaa ggaaaagtga acctgtgtag atattcccca ccttttgact
    32101 gtagagaata gactggtcaa aatgcttttg taagaggtct tttttctctt gaggcaggct
    32161 cttatccatg atttttttca agccttttag cgctaattta ggataaggca agtggaaaca
    32221 aacagccgca aaatcatcca aagtaagctg gtagcgtttt tgatattcaa gccaagtcgt
    32281 tttcaaacta tccaagtatt gttgggtaga atagacacca tttacataag gagttgtcga
    32341 gtaatttggt cgccagaaat ccatgatgtc acgggtctga gctacattgt cattattaaa
    32401 ggccatcatg cgtggatttt gtgtaatcaa catagctaca cttccagcac cttgagttgg
    32461 ttctcctgga gtttcaatac cgtatttggc aatatcactg gcaatgacca agaccttgga
    32521 ctccggagaa ttttccacat gcaatttggc ataatggagg gcagcagtcg ctccgtagca
    32581 ggcttcttta atctcgaaac tacgagcaaa gggctggatg cccagcaagc catgcacaaa
    32641 gacggccgca gccttactct ggtcaattcc tgactcggta gccacaatga ccatgtcaac
    32701 ttcttgtctt tcttgctcag ttaaaataga gtcactagca ctggccgcca aggtcacgat
    32761 gtcctcagtt aggggcgcaa tactcaattc cttgagtaag agtcctttac ttaatttttc
    32821 agggtcaatt cccctcgctt ctgctaagtc ttgtaatttc aagacatatt gactggtcgc
    32881 aaaaccaatc ttatcaatac cgattgtcat atttacctct gttttatcat tcatgtaaaa
    32941 aatcgttcta tactatttta tcacaaatgg cagtaaaaga gagaaaaaag acttgattca
    33001 ccaaatcaag cctcttattg gtcatcattt taaagaatga ttagttgcta gagagttcac
    33061 cgatataagt agctttataa gctccattca cagttatcag ctcctggagg atcaaatttc
    33121 ctgagtaagt ccttcccatc tcatctacaa atttttgata aaactgactg gtcggaattt
    33181 ctctgacatc cttatcaaat gtcttgtcaa gtgttttact aaccttctca gcaatcaatt
    33241 gatgctcttg ccatccactt tgaaactctg agcccgaact agaaaccatg actgggataa
    33301 acaacaaggt cagtagactt acagacaata aggaaagtag tagacttcct gcaaaactag
    33361 aatcctagtt catgattgat aatgccagca atcaaattca ttcgtaatcc gaagcgttta
    33421 cgatgatttc gataggttgt tgaaatcatt ttaaacgttt ttactttggc aaagatgttc
    33481 tcaaccttgc ttctctcctt ggatagcgca tggttataag ctttatcttc agctattagc
    33541 ggcttgagtt tgctggattt acgtggagtt tgtgcttgag gatatatctt catgggccct
    33601 tgataaccac tgtcggccaa gatttttcca gcttgtccga tatttctgcg actcattttg
    33661 aacaacttca tatcatgaca atagttcaca gcgatatcca aagaaacaat tctcccttga
    33721 cttgtgacaa tcgcctgagc cttcatagcg tggcatttct ttttaccaga atgattcgct
    33781 aattgttttt ttagggcgat tgatttttac ttccgtcgca tcaatcatta ccgtgtcctc
    33841 agaactgaga ggagttcttg aaatcgtaac accactttga acaagagtta cttcaaccca
    33901 ttggctccga cggattaagt tgctttcgtg aataccaaaa tcagccgcaa ttattcataa
    33961 gtgcggtatt ctcgcacata tagaaagcgt tgttaattta tttatctcat ttttcataaa
    34021 attcttttat ttctgtaaag tctacgatac tcgatgtgtt tttatataat gatacagtct
    34081 gagaatcact gttccgctag ccattccaat agagattacc aaagccaaca tgacaaccaa
    34141 ggtcgcactt gccagtgctt tattatagtc ccctgtcaca aaaaaggcag ttgttcggta
    34201 ggagagataa cctggaacca gcggtgccaa aatggccaag ataaagacca cagcaggtgt
    34261 cttataaaga atacttaaaa tctggctgac acaagaacca ataatggctg caatgaaggt
    34321 agctacaatg acattggtcg gttccttgag caagagatag attagccaga cagtcatgcc
    34381 caaaatccct ccaggtaaga gcatagaccg ttgcacattg agtacaatta aaaaagtgat
    34441 aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca tattagttca
    34501 tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc agggattcaa
    34561 acatcttact cataccagag tttatgtggt tggtcataat atcacggacc gcattggtca
    34621 aggcaatacc tggtacaaac ggcatgaccg caccagctat aatcaaatct gccgttgaag
    34681 gaaaacctgt gtagcgagcc caaaactggg caattatccc aaagacaaag gctccagcaa
    34741 aggctgtcac aaagggaatt cggataaatt tttccacata gagggaaaag gcaaaaccaa
    34801 ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac ataactgaaa
    34861 agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag ggaaggggtt
    34921 gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc cccccaacta
    34981 gctgacgaga aatctggttc acatcgcaga ctttttcgat gttataagaa gaggaggtca
    35041 cgcgcttcat gcgcgaaata ttggtatttt caatagagaa aaagatagcg gcaggcatgg
    35101 caaggacatt gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg gtatcttcta
    35161 cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata atcacatcaa
    35221 tgacggcatt taattctttt gattcttcca tgctttcctc cttttatcaa ctccctctat
    35281 tctatcacaa atccggactc aaaaaaaatc tttgccatga aatcatgaca aagattgatt
    35341 actcattttg attatccatc tgcttttaag gagtagctga agttgtttta ggtttgtaga
    35401 ttgaaatctt gactctagtc ttattgaggt ctaccttttc acctgctcta ggactttgtt
    35461 caacaaccat gccttctgca ctacctgcag gcgctgtcgt cacttctaca acttctatat
    35521 tagcttcctt aatcccaaca atttgaatca aattgttctt agtaaactcc aagctggaac
    35581 caatgtaact cggcatggca acacttgtaa cttttttagc tactgtcaag acaatttgag
    35641 taggtttact cacatcataa gtcgttccgg cacctggact ttgtttcata atcgttcctg
    35701 gttcgctttc gctggactct tcttcctcta tcttaatcaa attctcagga accttcttct
    35761 gcttgagttc tgagattact tctgtagagt tccgtccaat atagttccct aattgaatcg
    35821 tcgtagcttt tttagctact gtcaaaacaa tttgagttgc cttgctcaag tcataggtcg
    35881 taccttctgg tagactttgc ttcaggaccg ttccagcctc actctcattc gactcttctt
    35941 cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgcg ataacatcag
    36001 aagatttccg gccgacataa ttactaattt ggaaggattg tttgcctgat gagacaacca
    36061 gattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta cggataatcc
    36121 gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca aaattggctt
    36181 ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga atggcaatgg
    36241 ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca aggctggcca
    36301 acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt tggtaagttt
    36361 cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc gcttgaacct
    36421 taggaataga tgtcaaggta ctctgagaaa cctttggcaa ggtcttggta tctgccttgc
    36481 tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag ctactagaca
    36541 agtccacata catctctgaa accgagcggt agcgattggt caacttttta gcagttgcct
    36601 tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata acggacggca
    36661 ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca taagggatat
    36721 ggcctgtcaa catctcatag aaaataatcc ccatggcata gatatcactc tgcacagtcg
    36781 ccttcgaacc acgcgcctgc tctggtgaca agtaatgaac tgagcccaac atcgagttag
    36841 tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg accttggcag
    36901 tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca attcctcgag
    36961 tatgggccaa gcgcatagcc aagagaattt gtcccatgat acggactgct tcttcattag
    37021 aaagaggata atgttccttg atatagcgtt tgaggtccag tccagccaca tactccatag
    37081 ctaggtactg ttgaccgtct tcctcgccaa tatctgttat ccgaacgata tgaggatggt
    37141 ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc gggtccgtct
    37201 ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt aagtctttgg
    37261 ctaggtagac atccgccatg cctcctcgac caatctgttt gacaatccga tagcgtccgg
    37321 caaaaatctt gccgatttgg atcattctgc atcctcctcg ttcatagaaa caagggcaac
    37381 cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct ccgttttatc
    37441 tgctaaagga atatcactgg ttacaatatc acgaatctca ctgcctgaaa tcatgttggt
    37501 caagccgtca ctattgagca agagatagtc acctgactca aggataactg tcccaaaatc
    37561 aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt gcggatgagc
    37621 ttctgcctct tctggtgtca attgaccagc cttgagcaat tcattaacca aagaatgatc
    37681 gctcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat caccaatatg
    37741 agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc ccatgcctct
    37801 gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta ggtaatgggc
    37861 gaaccattca cgcacttcat tgactgtatc gatctgggta tcaacccaag ctacacccag
    37921 gtctgtcacc gccatttcac tagcgatatt ccctgcgcga tgacctccca tcccatcagc
    37981 taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt cttggttatt
    38041 tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt tccttcctaa
    38101 tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa ttcaggtgta
    38161 atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt tacctgctcg
    38221 aactcgggat gactctctaa aaagacctta acgacttgaa aattctcctc tgagacgata
    38281 gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac actacctaat
    38341 atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt gtatttgata
    38401 tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa aatcttatca
    38461 aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg agtttgaacc
    38521 cgatctgcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt gtggtcgtac
    38581 aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc tgttttccca
    38641 cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag cgtcggagca
    38701 accagctgac tggactcgtc ttggatggta atggctccat tcgcaaacaa attatgccct
    38761 gcaaaatgcc cttgctcctt aaccagacca gttgttgcta aaagggaatt attcgcctcc
    38821 aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact ggctttgttt
    38881 cgcactaaca ggctttcaaa gatggctttt gctctctcct ctccgtattc ttccttgagt
    38941 ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt ttttcgcttg
    39001 atgctagcaa tatctggcca gccttcacgc aagatacggc gaaggacagc gttgaccaat
    39061 ttttcactgc cttttttacg gagtttggcc aattccactg cttcattgac cacagcatga
    39121 tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag gacatagagc
    39181 cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc cagagtcaat
    39241 ttacgggcta ccgttccata gaccagctcg gtcactaagc ccttgtctgc tgcagagagc
    39301 tgactcccct tgaggtgttt atttaaggca atatttgaat atgcttgatt cacaaaaaca
    39361 tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac caaatcgttc
    39421 tcctacagtc aatgtacgtc caactccgtt gagaaaggaa gcaatgtcca tcttaggctt
    39481 accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga caatcaattc
    39541 tttcttgccg atagagagaa tctcacctgg atttccctga tcttctactg gtagggcttc
    39601 ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg ggttcattcc
    39661 acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt cttcctctgg
    39721 ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt tgatatcacc
    39781 agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg ccaatttttc
    39841 aaacaaggtg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag aaatcatatc
    39901 tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct catccccttg
    39961 aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg aggcatgaac
    40021 gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc caaaagcagc
    40081 agtcacaatt ccatctgctc ctagcttcat aagatcttcc atctctggac ttccagataa
    40141 tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga ctggggtttc
    40201 ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg ctagaatttc
    40261 gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg gggtccccat
    40321 aaagattagt tttgtcatat cttctccttt ttataaaaat tgctgcggct catggtcaat
    40381 gctgagacgg agctcactat tttcccgttc ttgagtcaag gccaagacct ggttgagggt
    40441 cggccccagc tcatcttcta aacggtattt aattaaaatc tggtaatgat agaggttgtg
    40501 ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg acaagcctga
    40561 ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt tcttgtgaga
    40621 aagggtaata ccaatcgtga aatagtaagg tggatagccg agttgtcgtc tgattcccat
    40681 ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag catagtgctg
    40741 cggattgtag gactgtatca agacttgacc tgctttttca gcccgacctg ctcgacctgc
    40801 cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca gattcaaggc
    40861 cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac cctttgcaat
    40921 catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa gcaaggcttg
    40981 gtgactgcct ttctttcgag tcgtatccac atccatcctc agaatgcgag cttggggaaa
    41041 gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac gaatactgtg
    41101 gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat aatggcagtt
    41161 catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac aagtatccac
    41221 cgtcccacac tcccgacaca tgacaaagct agaataacca cggcgattga gcatgagaac
    41281 cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag gcgtaaagtt
    41341 tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct cagggattgt
    41401 agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgtctt tgccagcacg
    41461 cgcccggctc tctaagctcg gcgttgcaga tccaagtacc agagttgctt gattatactg
    41521 agcccgtaaa atagctacct ctctggcatg ataacgggga ttgctgtcct gcttataagc
    41581 cgcttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag caaagatagc
    41641 agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc attcatcata
    41701 cttttcacca ttggataatc ctgagtgaag aatggctacc ttgtccccaa aacgtgctat
    41761 aaaacgctcg gtcatctgag gagtcaagga aatctcaggt accagcaaaa tagctgtctt
    41821 gcccttatcc agggcacctt ggataatctg caagtaaacc tcggtcttcc cacttcctgt
    41881 aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa ccgcatcacg
    41941 cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc cttcaaaata
    42001 agcagccgag cgtcgaactt ccttttggac tatggtaaca gcaccttgat ccacaaagaa
    42061 gttgacttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc tctctggatg
    42121 agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa tctcaacacc
    42181 ttctaattga gcatggtcaa cctcatacca agactgggtc ttgaccttct tttgatcgac
    42241 tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt cagcttgctt
    42301 ggcaaggtct agtgaagaaa aggctagcga atcttctgaa ccaaacaggc gcactcgttc
    42361 ttcctgactc aagccttcca gaggatagag aatcttgtca tagctagaat tcagaaatcc
    42421 tggaagcatg gccttgagga tagagatttt gtaggagaag acagatttgc gtaactcctc
    42481 agccagccag agttgttctg gcgtgagaac aggagaaaaa tccagcacct ctgcaatatc
    42541 ttttaaatct tgctccatct cttctccatc tgattgggac tccaaaccaa gaacaatccc
    42601 ttgaatcagg cgattaccct taccaaaagg tacatgaacc cgcatcccaa cttccagcat
    42661 tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca tcaagggcac
    42721 atctacgata atcttagcta gggccatctt ctcacctcct ccttgtcagt acattcttgc
    42781 aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc ttctttttct
    42841 ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt ttcttcttcg
    42901 atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt aacgtttcct
    42961 gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc ttgagttgct
    43021 ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag tgaatatttt
    43081 gaaggaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg cttgtaccta
    43141 ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata gtgaccaatg
    43201 acacgatcca cacagaagtg ttctgcttca atcacacatt tgacacgttc agcagctagg
    43261 ggcacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat ttcttccttg
    43321 gccttttcga ttcgttgggc aatcacttct gcactatctg ttccacgacc taccaagcga
    43381 tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc tggaaccttt
    43441 ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat tcccttgtcc
    43501 aaggtttcat tgacataggt cagaggagtt ccatagtagt tgccgacata ttctgcgtat
    43561 tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg gaagaaatag
    43621 tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac agagtattga
    43681 aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc aacccctgaa
    43741 ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt tagtcaatct
    43801 gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta cagtctttct
    43861 atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta tttagcataa
    43921 tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata atcgagattg
    43981 ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc cttgattttt
    44041 cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct agtttgcact
    44101 ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta gctttcaaga
    44161 gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc gacgataact
    44221 gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt caccacaact
    44281 gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct accttcaacc
    44341 tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc aagagccgca
    44401 ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat cgaatggcgc
    44461 aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt catcaagtct
    44521 ggatgaaggt ttggcgcacc aatttcatag gcagcagcct caccgtattc acgaatctta
    44581 ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg atgtatacga
    44641 ccatctttga gcaacatttc catagtcata cgggcaatct cacgacgaat cggatcaaat
    44701 cctgacaagg tcaccacttc tggtgtatcg tcgataatca catcgacccc tgtcaaactt
    44761 tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat agtatcgtct
    44821 ggcagatgaa ctgttgagtt tgttgactcc gctacatatt caccagcgat acgttgcata
    44881 gcttgaacca agatgtcctt ggccattttg tcagaacgtt ccttgacctc ttgctcagct
    44941 tcgcgaatgc gactggcaat ctccctggtc aagttttcct ctgtctgagc caagataata
    45001 tctcgtgctt ctgcctgaga cagagcacca atacgctcta gttctgcttc tttttgtctt
    45061 tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc agaaatactt
    45121 tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt acggtcaagg
    45181 ctagtagctc tctctgtcaa acgactttcg atttgtttga gttcttgacg ttctgattta
    45241 aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc caatagtgct
    45301 tcttttttaa gagacttgct ttcacgtttg gcttcattaa caagtaaatc cgcttcacgc
    45361 tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat caactctgca
    45421 gcttcatgag atgatttcat cttagctgag atgctgacat atccaatgac taaaccaatg
    45481 atgacggcaa aaacagcaat cgcaagcgac atgatctcca tgtttttacc tcattttatt
    45541 gttattccga atgacacaca ttcttttaca ttctaccata aaaaagtgat tttcacaaac
    45601 ctaaaataga atatgttttg gggaatttag tctgaatttt aggattacac ttccttggtt
    45661 ttttaaggag ataagtcagt gtcgctatca aaaagttcca ccgaatttct acaactatgg
    45721 attttctatt gttgtgccaa atagtgttcc actagattca aacattttgc tttcaagtct
    45781 ttgaaaattc actttaggaa attacagctt atcttcaaga tcaaatttgt cataaattaa
    45841 ctttttttat ttagttgtat caatttattt cttaagtatt aatttatcct catcgaaagc
    45901 ttttaaaata tactcattaa tcaatttatt atcttcttca ttttttgaaa aataagtttt
    45961 aatattattg ggagttctat gttctagtag acgatggata acatcatcac ttctatcatg
    46021 gaaccaggtc caatctactt caggataaag tcctcgaata tcttcttcaa tatcttttaa
    46081 aatctcaaaa tcagaaaaat atccttttct acttaagttg tataaatctg atacagactt
    46141 ttctcttggg tctgggaaag ttttaacccc ctcaactctt ttatcattaa ttcttttaat
    46201 caaataatgg tagattttat tttgtatctg aggaaaatca tagacattat aactcatcaa
    46261 atcaattact ttatggtaaa taatattttc tgattcttca taaactttta gagtatctag
    46321 aatgtcatct ttaatatcct tttcgaaata cttaaataag tggcatatca agtcagaata
    46381 ttctatgata ttttttatat catcattttt atattttatt cttaaaatat ctgtattaaa
    46441 tttttcgagt actattattg cagtttcctg atcagttgag cagtattcta gtaactgtga
    46501 atagagtgga tacactgaat tatataaaga aaaatttttc tccaaaattt catttaaatg
    46561 tttatttaca atcccaatta tcttagattt caatgaatct ttatcaataa catccatatt
    46621 atcgaggaca attttaataa ttctcctaaa ttcctcgctc caattataat acagtgtttg
    46681 attatttaaa atttctatta ctttttctat gtcaatatca tcaacaagag gaagaaaaat
    46741 tagcatattt ttaagctctc gaagattttc atcttcagta atttcaagtc tttcttgaag
    46801 ataagtaatt cgattcaaca agtagtcttt cgcttcctca gtaactttta ttttaccaaa
    46861 tgaatagttt ctaaaatata aatttacaac cttaaaatct atattcggaa gaattaattg
    46921 aacatcatcc aaatcaagat ttttaagcca agaagatgtt ctatcgaaaa tacttgagtc
    46981 aggatttaca tatgaattat cataactgag taataatatt tctaaatatc tattaatgat
    47041 tgatttataa atcttataat gttcaacaca taaacaattt aattttaaaa agttataaag
    47101 attttttact gtaaactccg cattaaatag atgattatta gcagaccatc ctcctcttct
    47161 atagctttca tgctcttcac gaatttcatc aaataattca ttaatagttt ctaattttct
    47221 atataaaaaa ttgaagttaa ggattgaatc tctaaaaaat tctataatct ttttctcatc
    47281 tcctgtaacc gagttaataa tttgttctgt taattcgctt aattctccat cataaagtgg
    47341 ctctgcataa ctaggtgttt tttcgtatct atcaattatt tgaatttgct gaaaattaaa
    47401 ttcacaaact aagaaattaa aatagtcttt ctgacgaaat gctatattag ctagttctct
    47461 aaattttgct tttgctaaag aatattgttt ttcttcatac aacttaaaag ccttacttaa
    47521 gaatcgattc ccctttaaat ccctaggttc accaatctcc atatctagaa agcgatttaa
    47581 taaagatttt ttagatacca taattcgtaa ttcttcatga ccatcaattt caaatcttaa
    47641 ttgatcattt ccaaaccagc aatactcatc atcccagttt aaagcccttt tctttaaatc
    47701 agaatatcta gaaaaatctt tcgcatcaat aaaactaagt ctatctaaaa aagccagttg
    47761 attccataaa tcatcagcat tatttacatc ttgacttcgg ttttctgata gaacctctaa
    47821 aaaatctttt gtcctgcaat acaatttgtt ctgtttttct gatgtctcct gacctagatt
    47881 ctcttcatta gagataatga aaattccttg cttcttataa tactctcgaa tgatcataga
    47941 cggttcctcg ggagtataaa aataagcatt tttagcatcc aatttaaatg tattttgaat
    48001 cattctaaaa attgaattaa aagtcgaatc acttagagaa taccccacaa acaatagagt
    48061 atgattcatt atcaatgact ggattaaagt agaaatcatt gggaagttca aatgatagtc
    48121 taaataatca tcttctttca aaacaatatt tttcttactg aagtcaccat gcattttaat
    48181 caagtatctt tccgaactcg tataagggat gtctttatcc tcagcgacta cattgtactt
    48241 taacaagcca ctttcaaatt gactctccag aagtgaatca tagtttgtcg taataatatg
    48301 ttttggtgca attttttcta ttaatttatg taactcattt ggtttactca atcccttctt
    48361 aaagaaaatt tcttctatct tctttgtgta ctgatttttc ccaaaagtat cataataata
    48421 ctgagcaatt ctcagtggac tatctgttct ttcttctggt atgttcaatt ctttttttaa
    48481 tgattgaatc aattctcccc aagttggtag attagaatta gctgatattc ctgcaccaac
    48541 aaacaaaact aaggaatttt ctttaataga attctttatt tgagttatag ataaattata
    48601 attttcttcc atattttaac tatcctacat tagcttgtac tacataaata caaattatcc
    48661 ttataaatct tcttttttat tacataatct taaacaaaag tttatcatgg tttataaata
    48721 taaaaattta tttgt
//
LOCUS       DAVHSL010000010        48603 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000010 DAVHSL010000000
VERSION     DAVHSL010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.010"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(202..1188)
                     /locus_tag="VVR39_000573"
     CDS             complement(202..1188)
                     /locus_tag="VVR39_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6030111.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1198..1998)
                     /locus_tag="VVR39_000574"
     CDS             complement(1198..1998)
                     /locus_tag="VVR39_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU6030112.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTENFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2251..3093)
                     /locus_tag="VVR39_000575"
     CDS             complement(2251..3093)
                     /locus_tag="VVR39_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6030113.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3095..4387)
                     /locus_tag="VVR39_000576"
     CDS             complement(3095..4387)
                     /locus_tag="VVR39_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6030114.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4498..5769)
                     /locus_tag="VVR39_000577"
     CDS             complement(4498..5769)
                     /locus_tag="VVR39_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6030115.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKSADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6319..7836
                     /gene="malQ"
                     /locus_tag="VVR39_000578"
     CDS             6319..7836
                     /gene="malQ"
                     /locus_tag="VVR39_000578"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU6030116.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7862..10120
                     /gene="glgP"
                     /locus_tag="VVR39_000579"
     CDS             7862..10120
                     /gene="glgP"
                     /locus_tag="VVR39_000579"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU6030117.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11165..11737)
                     /locus_tag="VVR39_000580"
     CDS             complement(11165..11737)
                     /locus_tag="VVR39_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030118.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12338..13186)
                     /locus_tag="VVR39_000581"
     CDS             complement(12338..13186)
                     /locus_tag="VVR39_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6030119.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13338..13616
                     /locus_tag="VVR39_000582"
     CDS             13338..13616
                     /locus_tag="VVR39_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030120.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13618..15681
                     /locus_tag="VVR39_000583"
     CDS             13618..15681
                     /locus_tag="VVR39_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6030121.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15759..17015)
                     /locus_tag="VVR39_000584"
     CDS             complement(15759..17015)
                     /locus_tag="VVR39_000584"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU6030122.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17157..19622
                     /locus_tag="VVR39_000585"
     CDS             17157..19622
                     /locus_tag="VVR39_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6030123.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPIQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGASATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19687..20598
                     /locus_tag="VVR39_000586"
     CDS             19687..20598
                     /locus_tag="VVR39_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6030124.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIVLIILPMIFLSIEEAKESR"
     gene            20828..21526
                     /gene="dapD"
                     /locus_tag="VVR39_000587"
     CDS             20828..21526
                     /gene="dapD"
                     /locus_tag="VVR39_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU6030125.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21594..22724
                     /locus_tag="VVR39_000588"
     CDS             21594..22724
                     /locus_tag="VVR39_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU6030126.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILAYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22736..23275
                     /locus_tag="VVR39_000589"
     CDS             22736..23275
                     /locus_tag="VVR39_000589"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU6030127.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDVSKIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23259..23936
                     /locus_tag="VVR39_000590"
     CDS             23259..23936
                     /locus_tag="VVR39_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU6030128.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGSAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24008..24907)
                     /gene="galU"
                     /locus_tag="VVR39_000591"
     CDS             complement(24008..24907)
                     /gene="galU"
                     /locus_tag="VVR39_000591"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU6030129.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKNGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24929..25945)
                     /locus_tag="VVR39_000592"
     CDS             complement(24929..25945)
                     /locus_tag="VVR39_000592"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6030130.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26157..26538
                     /locus_tag="VVR39_000593"
                     /pseudo
     CDS             26157..26538
                     /locus_tag="VVR39_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(26712..27137)
                     /locus_tag="VVR39_000594"
     CDS             complement(26712..27137)
                     /locus_tag="VVR39_000594"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6030131.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYKARGQGKTCLTE"
     gene            complement(27205..27855)
                     /gene="phoU"
                     /locus_tag="VVR39_000595"
     CDS             complement(27205..27855)
                     /gene="phoU"
                     /locus_tag="VVR39_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6030132.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27870..28622)
                     /gene="pstB"
                     /locus_tag="VVR39_000596"
     CDS             complement(27870..28622)
                     /gene="pstB"
                     /locus_tag="VVR39_000596"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6030133.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28624..29439)
                     /gene="pstA"
                     /locus_tag="VVR39_000597"
     CDS             complement(28624..29439)
                     /gene="pstA"
                     /locus_tag="VVR39_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6030134.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29432..30295)
                     /gene="pstC"
                     /locus_tag="VVR39_000598"
     CDS             complement(29432..30295)
                     /gene="pstC"
                     /locus_tag="VVR39_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6030135.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30413..31288)
                     /locus_tag="VVR39_000599"
     CDS             complement(30413..31288)
                     /locus_tag="VVR39_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU6030136.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31455..32786)
                     /locus_tag="VVR39_000600"
     CDS             complement(31455..32786)
                     /locus_tag="VVR39_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU6030137.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLSGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32787..33494)
                     /locus_tag="VVR39_000601"
     CDS             complement(32787..33494)
                     /locus_tag="VVR39_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6030138.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33578..33880)
                     /locus_tag="VVR39_000602"
     CDS             complement(33578..33880)
                     /locus_tag="VVR39_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6030139.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(33867..34088)
                     /locus_tag="VVR39_000603"
     CDS             complement(33867..34088)
                     /locus_tag="VVR39_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6030140.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            34050..34607
                     /locus_tag="VVR39_000604"
                     /pseudo
     CDS             34050..34607
                     /locus_tag="VVR39_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34922..36613)
                     /locus_tag="VVR39_000605"
     CDS             complement(34922..36613)
                     /locus_tag="VVR39_000605"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU6030141.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36749..37195
                     /gene="argR"
                     /locus_tag="VVR39_000606"
     CDS             36749..37195
                     /gene="argR"
                     /locus_tag="VVR39_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6030142.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37246..39780
                     /gene="mutS"
                     /locus_tag="VVR39_000607"
     CDS             37246..39780
                     /gene="mutS"
                     /locus_tag="VVR39_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU6030143.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39927..41621
                     /gene="patA"
                     /locus_tag="VVR39_000608"
     CDS             39927..41621
                     /gene="patA"
                     /locus_tag="VVR39_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU6030144.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGTWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILALQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(41951..42214)
                     /locus_tag="VVR39_000609"
                     /pseudo
     CDS             complement(41951..42214)
                     /locus_tag="VVR39_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            42412..44178
                     /gene="patB"
                     /locus_tag="VVR39_000610"
     CDS             42412..44178
                     /gene="patB"
                     /locus_tag="VVR39_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU6030145.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44317..45006
                     /locus_tag="VVR39_000611"
     CDS             44317..45006
                     /locus_tag="VVR39_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6030146.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            45010..45189
                     /locus_tag="VVR39_000612"
     CDS             45010..45189
                     /locus_tag="VVR39_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030147.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45176..46525
                     /locus_tag="VVR39_000613"
     CDS             45176..46525
                     /locus_tag="VVR39_000613"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU6030148.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLIKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46649..48109
                     /locus_tag="VVR39_000614"
     CDS             46649..48109
                     /locus_tag="VVR39_000614"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU6030149.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            48123..48557
                     /locus_tag="VVR39_000615"
     CDS             48123..48557
                     /locus_tag="VVR39_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6030150.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVSELIPYWWGEERASKFNER"
BASE COUNT        14304 a         9213 c        10568 g        14518 t
ORIGIN      
        1 ctcaaaacag tgttttgagc aacctgtggc tagcttccta gtttgcactt tgattttcat
       61 tgagtataaa aagatcttgg gaaaagactc aatttcagta gaaaaggaag taaatcttcc
      121 cacaataaaa cgcatagtat caagtttttt caatacctga tagtatgcgt ttttgctttt
      181 aacgactttt tgcccagtct cttatttttc gataattttg tgggcgatca attgacggta
      241 acaaatttgt ttattgtttt tattatcatt aataatctgg agaatagttt caagggaaac
      301 acgaccaagc tctaaactat tgatatcgac ataggctgcc aagttgagct tgggattaac
      361 cgagtcaaag ctgagaacag ggacatccag ctggtgtttg gcaatatagt tacaaacacc
      421 ttcagctagg aggctatcgg ttgtgatgat agcatcaatt tgtggatcgt gcttgaataa
      481 tcgcttgcta aatttatagc ccttttcttc cagaaactcg tcggcaaagt agatgcgatt
      541 gttgtcagtg gtaagtttgt aatgtttaag cgcctgttca tagcctgtta aacggtcttt
      601 ggtcacgaag agctttttac ttcctccgat aaaggcaatg cgtttgcagc cttttttgat
      661 gaaatattca gtcgcatcaa aaccagcttg aacattgtcg ttgtcgacaa gtgggatgaa
      721 aggagataga gatttaccta ggataaggaa ggggaactgt tcttctgcga cgagttttac
      781 gagagggtct tcttcttggg catagagaaa gattagccca tctacacgct tgccgtagac
      841 catttgtgaa atagcgttga gacgctcctt ctcatctttc cctgttgcta tctgaatggc
      901 atagtggttt tcagatgcga cttgagagat gccacgtaga accgatggaa agaaaggatt
      961 ctggtagaag gcgtctgagt catcaggaag aactaatccg ataacctgag tatagctgct
     1021 taccaagcta cgagcgttga ggtttgggtg gtagttgagt tccttcatag ctttgcgaac
     1081 gcgttttttt gtttcgtcgc taatggttga tttattttga ataacacggg ttacggttga
     1141 aggcgaaaca ccagcagcct tggccacgtc tttaatcgta acgggcataa aaatctccta
     1201 tttatggtaa tttggatcac ggaaatgtgt tttataaaag atagtgacca gatacagaac
     1261 aaaaagaata ttttgtacag taatcagggt tgtcatattt tggccaaata atcccaaaat
     1321 aagtgtaatc agagtcggca atcctaaaca gttcaagata aagtgatagc actctttaaa
     1381 ggttctaaat gaaaagaggc gtgatttctt agtgatataa aggagaagac tagctcctag
     1441 agagacgata aagaaattca aaccaaagag gaagctcgca ccgagaacta ggaagaggct
     1501 gatatagaca cgattttgtt ggtaccagtc tttagaaatt gcttgggtca agctgtcttt
     1561 gcttttgaaa ttctcagtct gaatggctcg gtaagagatg cgggtcagtt ccttgctttc
     1621 cttgctgatg actagctcat ttgtatcgaa atgcagttgc aagtccttag gtaattcctt
     1681 gatttgactt ggaccaatca caacagaagg ggtttgacta gctgttccag tataagttaa
     1741 tgtgccatcg acaattgtag catgttcaga gagatcctgg acaacctcat ttgtcagagg
     1801 ttcatagaca ttatcgataa aagtttctag cggataggtc tcctgggagc tgttttggat
     1861 agcaatgggt accatagaca agctgataag gaagatactg gtaaagagaa gttgaaacca
     1921 gttgagctcg aaacgtttgg acaggggctt acgaaacccc caaatacttg aaaaatagga
     1981 aaatggatat ggaagcatag gtatctttct aaaaggtgtt ttctatatga gtattattat
     2041 atagagaaat gcgctttatt tcaagtctag gagaaaaatt gcttgctaca aggatattat
     2101 ttacagtgac aattgctaat aatcaatgaa aatcaaagtg caaactagcc acaggttgct
     2161 caaagcacaa ctttgaggtt ggagataaag ctgacgtggt ttgaagagat tttcgaagag
     2221 tataaaatga aaaagggtgg cggggataaa ttatcccttg tcgccaccac ttgtaagtcc
     2281 tgaaacaaag ttcttttgta gaaagaagaa gagaatacag attggaaggg cgatgaggat
     2341 agcacctgct gagaagtagg caatcttcaa gtttttcgca ttgttaacga aggtttggag
     2401 acctacggca acagtaaagt attctttctc acgaagcaag aaactagaga ggatgtagtc
     2461 cccgaaaggt cccatgaagg cccagagagc ttgtacggca accattgggc gaacaagtgg
     2521 tagaacaatt tgccagaagc ggcggaagtg tcctgcaccg tctagttttg cagattcgtc
     2581 taaagacatt ggcactgtat cgaagtagcc tttcatgagc caagcattca tcgggatacc
     2641 accaccaacg tagaggaaga tgaggaacca gttgtggtta agggcgttca acataagcgc
     2701 cataacgaag aaggctgtca aagcggccat agttggcacc atttggatga tcaagaagaa
     2761 gaccaaactt tgtttacgag ccaagaagtt gtaacggctg taagcataac cagcaagtac
     2821 gatgatactt gtttgaacag ccatggtaat taaggcgata atcaaagtgt tgaggtacca
     2881 agtaccgtac aaggtttcag tgaagaggcc tttaaagtta tcaaaattga ggtcgatatt
     2941 agtatctagt ttaaaggctg agacgttacc tgctttaaag gctgacataa tggtaatcaa
     3001 cagtggatag ataattacaa ttgatagacc aatcaggtaa aggtaagtaa ggctttgagt
     3061 cagtctacgt ttgagtttaa ttgagttatt catcttagac gtcctccata tcaaatgcgt
     3121 gtagtttctt gaatgcgatc atagagattg agatgacaat gatagagata atcaaggtaa
     3181 cagctgccgc cattgagtat tgaggagatg tacctgttgt caaacggtag atccatgaga
     3241 tcaagatatc ggttgaacca gctccacctc cgacactacc aggtcctcca ccattgaaga
     3301 ggtacatgat agagaagttg ttaaagttga aggtgtattg gctaatcaaa gtaggtgccg
     3361 caacagccaa aatcattggg aaagtgatgt tgcggaattt ttgccaagcg ttggcaccgt
     3421 caatataagc tgcttcgtaa aggtcgttag gaatagattg caagataccc aaagtcaaaa
     3481 cgtagatgta tgggaatccg agccaacctt gcatcataat caaggcaatc ttagtccaag
     3541 ttgggtctgt tttccaagga ataagagctc catcaaggaa aggaaggaat ttagccaaga
     3601 ttggcaatac ttgagtgttg atagcaccga cactatcgtt aaacatgttt gagaatgtca
     3661 agatagtgat gaaggctggg acagcccaag gaagaaggaa aataacacca aagatacgtt
     3721 ttcctttgat aaatggttgg ttggcaatga tagctgtgaa gataccaatt acgatttgta
     3781 aagtagaagc tgccaaagcc caaatgatag tccaagaaag aacagaacca aaggcagaac
     3841 ggaaggtact caagctccaa atgtttgtaa agttggtcaa accaacccag tccaacaact
     3901 tgtttggtgg caagtgttgg aagtcgtagt tggtaaaggc gatcatcaag gttacgataa
     3961 ctgggaagat aatcgcgaag gtcatggcaa cataagatgg aatgatcaag aggtaaggga
     4021 agccattttc ataaatccct ttgatcatgt ctttgagtgt gcgtggaact ggaattccat
     4081 tgttaatgcg ttttgcaatc gtatgtgcat ctttgatatt tgagaaataa aagagtacat
     4141 aaacgattac aaagattaga tggaaggcac cacgaatcag cataaagagg gaattatcac
     4201 gacctggttt gtcaccaaga gtgatgaggt tgctcaattc aggggttgca agtgctagga
     4261 agtaaaggac aaatacgatg gttacaccaa ggaagataaa acctttggct ttttgtttat
     4321 tgtaaatctg tcctaaccca ggaatgatag acagcagggc tgctttacta ggttgttgct
     4381 tttccatatt aactcctttc ataggatact acttttttat aagaaagcta aattatttgt
     4441 gtctctattg ataaattcaa agggggattt gatttccacc ccccttgaac aaatttttta
     4501 ttcaccaaat ttttgtttga ttgtttcttt gatcaatgtt acagcatcgt tagcagctgt
     4561 tttagcatct ttttgaccac ttacagcatc aaagagcata tttttcgctg gatcccaaac
     4621 tgcagacatt tgagagatgt ttggcagtgg ttgagtgttc ttgaactgtt tgataacagc
     4681 tgttgtcaac tcatcgtttt taccttcagc gtatgaacga gcctcagtat tagctgggat
     4741 ttcgttagtc ttatcatata atactttttg ttgttcagtt gcaacaagga agtctacaaa
     4801 tttttgagaa gcttcaaggt tcttaacggc ttgaggaatg acccaagctt taccaccacc
     4861 gaatgcagca tattcttttc catttggaag agttgggata gttgcaactc cgtagtttac
     4921 tttagcatct ttaaaggctt gagctttcca aggtccgtcg atgatagcag ctgttttacc
     4981 ttcttggaat tgagtttgga ttaagtttcc agcaccttct gtatcttgca tacctttagg
     5041 ccatttttcg taccaagatt tagcgtagtt gatacctacg atagaaccgt cgtttgcaag
     5101 accgatgtct ttagcgtctt taccgttttg gccaaagacg taagcaccgt taccggcaag
     5161 aagtccatat gtatagtaga agtttgtcca gtcagctagg aaggcagtag ttttaccatc
     5221 ttcaccagcg aatgcgtatt tgctatcttt agcaaggttt tccaagtcag caaatgtttt
     5281 tggagcatct ttcaccaagt ctttgttgta gtacataaca agtgactcga taacggcagg
     5341 agcaccgtaa actttaccat tagcagctgt tacaagagat ttagttgtgt cgtctgtttt
     5401 agcaccatcg ctcaatttca cttctgaaag ttgtccgtca gaaccaaggc tacctacacg
     5461 gtcgtatgga gccatcataa catcagggac attaccagat tggttgtcaa gagaaagttt
     5521 atcaagacct cctagagcat caccagtttt aagagtgact tttactccag cttctttttc
     5581 ataagcttta gcaacctctt caatatagct cttatatccc tcgtctacat atacagtgag
     5641 ttctttgact tcagatgaac cagaatcagc agacttatca gcagttttgc ttccgcaagc
     5701 taccaaaagc aagctagcaa gtgtaacagt tccaagcacc gcagtgctct tcataaattt
     5761 agatgacata gtgtattcct cccaaagaat agcaagtttt attgataagg aaacgcaaac
     5821 gttttccttt atgagcttag tatagcacaa atagaaaacg gttgcaagta ttttttgtaa
     5881 aaattttaaa aaatttttaa gcttgatttg atagcataat tttgcatttt aatagaagaa
     5941 aagtatgaaa tagataagaa tacagtattt ttaataaaaa tatatggaat ctgtctaaag
     6001 agggaaacca ggaggggcta cctccctgtt tctaatccct atctattttc tatagacgtt
     6061 tgtgctttgt tacatataaa ttcaagctcc ctaaggaggt tttgtacttt gtagactgtc
     6121 tcgtgagagt caaactttag gattagatag ttttaagtta tctttgctaa aatgagttag
     6181 tctccttaaa aataatcaaa aaagtttttt aaaaacgctt gcaattatgc ttgaaaagga
     6241 gtatacttat aagtaacgca aacgtttgcg tctgcaaaat acgcaacgtt ccattatttt
     6301 aacacacgag gtgctattat gaaaaaacgt caaagtggtg tgttgatgca catctcttct
     6361 cttccaggag cttacggaat cggatcattt ggtcaaagtg cttacgactt cgttgatttc
     6421 ttggtccgta caaaacaacg ttactggcaa atccttccat taggagcaac tagttacggg
     6481 gattctcctt accaatcttt ctcagccttc gcaggaaaca ctcattttat cgatttagat
     6541 atcttggtgg agcaaggttt gttggaagca agtgaccttg aaggagttga ctttggtagc
     6601 gatgcgtctg aagttgacta tgctaaaatc tactatgcac gtcgtcctct tttagaaaaa
     6661 gcggtgaaac gtttctttga agtcggagat gttaaagatt ttgagaaatt tgctcaagac
     6721 aaccaatcat ggcttgagct ctttgctgag tatatggcta tcaaagagta ttttgacaat
     6781 cttgcttgga ctgaatggcc agatgcagat gctcgtgctc gtaaagcttc agcacttgaa
     6841 agctatcgtg agcaattggc agacaagttg gtttaccacc gtgtgactca atacttcttc
     6901 ttccaacaat ggttgaaatt gaaagcttac gctaacgaca accacatcga aatcgttggg
     6961 gacatgccaa tctacgtagc ggaagattca agtgatatgt gggcaaatcc acatctcttc
     7021 aaaacagatg tcaatggtaa ggctacttgt atcgcaggat gcccaccaga tgagttttct
     7081 gtaactggtc agctttgggg taatccaatc tatgactggg aagcaatgga caaagacggc
     7141 tacaaatggt ggattgaacg cttgcgtgaa agcttcaaaa tctacgatat cgttcgtatc
     7201 gaccacttcc gtggcttcga atcttactgg gaaatccctg ctggttccga tacagcagca
     7261 cctggtgagt gggtgaaagg tccaggctac aagctttttg cagccgttaa ggaagaactt
     7321 ggtgagctaa acatcatcgc agaagacctt ggcttcatga cagatgaagt gatcgaatta
     7381 cgtgaacgta ctggcttccc aggaatgaag attcttcaat ttgccttcaa cccagaagac
     7441 gaaagcattg atagcccaca cttggcacct gctaactcag ttatgtacac aggaacacac
     7501 gataacaata cggttcttgg ttggtaccgt aatgagattg atgatgcgac tcgtgagtac
     7561 atggctcgtt acacgaaccg taaagaatac gaaacagtgg tacacgctat gcttcgtaca
     7621 gtattttcat cagttagctt tatggcaatt gcaactatgc aagatttact agaattggat
     7681 gaggcagctc gtatgaactt cccatctacc cttggtggaa actggtcttg gcgtatgact
     7741 gaagatcaat tgacaccagc tgtcgaggaa ggtttgcttg acttgacaac aatttatcgc
     7801 cgaattaatg aaaatttggt agatttaaag aaataagaca ataatcagga gacaactaaa
     7861 catgttatca ctacaagaat ttgtacaaaa tcgttacaat aaaaccattg cagaatgtag
     7921 caatgaagag ctttaccttg ctcttcttaa ctacagcaag cttgcaagca gccaaaaacc
     7981 agtcaacact ggtaagaaaa aagtttacta catctcagct gagttcttga ttggtaaact
     8041 cttgtcaaac aacttgatta accttggtct ttacgacgat gttaaaaaag aacttgcagc
     8101 tgcaggtaaa gacttgatcg aagttgaaga agttgaattg gaaccatctc ttggtaatgg
     8161 tggtttggga cgtttggctg cctgctttat cgactcaatt gctactcttg gtttgaatgg
     8221 tgacggtgtt ggtcttaact accactttgg tcttttccaa caagttctta aaaacaacca
     8281 acaagaaaca attccaaatg catggttgac agagcaaaac tggttggttc gctcaagccg
     8341 tagctaccaa gtaccatttg cagactttac tttgacatca actctttacg atattgatgt
     8401 tactggttat gaaacagcga ctaaaaaccg cttgcgtttg tttgacttgg attcagttga
     8461 ttcttctatt attaaagatg gtatcaactt tgacaagaca gatatcgctc gcaacttgac
     8521 tctcttcctt tacccagatg atagtgaccg tcaaggtgaa ttgctccgta tcttccaaca
     8581 atatttcatg gtttcaaacg gtgcgcaatt gatcatcgac gaagcaatcg aaaaaggaag
     8641 caacttgcat gaccttgctg actacgcagt tgtccaaatc aacgatactc acccatcaat
     8701 ggtgattcct gaattgattc gtcttttgac tgcacgtggt atcgagcttg acgaagcaat
     8761 ctcaattgtt cgtagcatga ctgcctacac taaccacaca atccttgctg aggcgcttga
     8821 aaaatggcct cttgaattct tgcaagaagt ggttcctcac ttggtaccaa tcatcgaaga
     8881 attggaccgt cgtgtgaagg cagagtacaa agatccagct gttcaaatca tcgatgagag
     8941 cggacgtgtt cacatggctc acatggatat ccactacgga tacagtgtta acggggttgc
     9001 agcactccat actgaaatct tgaaaaattc tgagttgaaa gccttctacg acctttaccc
     9061 agaaaagttc aacaacaaaa caaacggtat cactttccgt cgttggctta tgcatgctaa
     9121 cccaagattg tctcactact tggatgagat tcttggagat ggttggcacc atgaagcaga
     9181 tgagcttgaa aaacttttgt cttatgaaga caaagcagct gtcaaagaaa aattggaaag
     9241 catcaaggct cacaacaaac gtaaattggc tcgtcacttg aaagaacacc aaggtgtgga
     9301 aatcaatcca aattctatct ttgatatcca aatcaaacgt cttcacgagt acaaacgcca
     9361 acaaatgaac gctttgtacg tgatccacaa ataccttgac atcaaagctg gtaacatccc
     9421 tgctcgtcca atcacaatct tctttggtgg taaagcagct ccagcctaca caatcgctca
     9481 agacattatc catttaatcc tttgcatgtc agaagttatt gctaacgatc cagcagtagc
     9541 tccacacttg caagtagtta tggttgaaaa ctacaacgtt actgcagcaa gtttccttat
     9601 cccagcatgt gatatctcag aacaaatctc acttgcttct aaagaagctt caggtactgg
     9661 taacatgaaa ttcatgttga acggagcttt gactcttggt actatggacg gagctaacgt
     9721 ggaaatcgct gagttggttg gtgacgaaaa catctacatc tttggtgaag attcagaaac
     9781 tgttatcgac ctttacgcaa aagcagcata taaatcaagc gaattctacg ctcgtgaagc
     9841 tatcaaacca ttggttgact tcatcgttag tgatgcagtt cttgcagctg gaaacaaaga
     9901 gcgcttggaa cgtctttaca atgaattgat caacaaagac tggttcatga ctcttcttga
     9961 tttggaagac tacatcaaag tcaaagagca aatgcttgct gactacgaag accgtgacgc
    10021 atggttggat aaagtcatcg ttaacatttc taaagcagga ttcttctcat ctgaccgtac
    10081 aatcgctcag tataatgaag acatctggca cttgaactaa tactcttcga aaatctcttc
    10141 aaaccacgtc agctttatct gcaacctcaa agcggtgctt tgagcaacct gcggctagct
    10201 tcctagtttg ctctttgatt ttcattgagt ataagataca aatttatact aatacatttt
    10261 gtaaaaaagt gagtttcgat tgaaattcgc ttttttaaat gctgtggatt tgggtcaatc
    10321 ttgtctaaaa atagggaaat cctagataca gtgaaggctt taaatgctgg tttttactgt
    10381 cttcagcctt atattttttc gtagttggtt acctcatatc tcttgtattc gcttacataa
    10441 agtattataa tataattgta ggaaagaagg tgtttttatg atatacacac ttaaattggt
    10501 gttgtttatt acctttcttg taataagctt gttacctgat aagatttttg gaaaaaataa
    10561 aaaaatttgg aaaatagttt ttgcaatatt gacggcagtg gcagcattgt catttatgta
    10621 ctaagttatt ttaagaatgt agggaaataa accctacatt ctttttagtt ttttctgttt
    10681 tctaaattct atttatccaa gcgcttcaac atttcttgct tcttcgcttc aagttctgca
    10741 cgcttttctt cgatttcggc atgttttttc tcgagttcag aacaacttgc accattgcta
    10801 aattcttttc gccatcagga gatagggtga gtcgacatgt ctattactca cccaaagcag
    10861 tcctacaaag caggaatttt ctgttacttt tttggaaata gtaacgttta tacagctttg
    10921 gcacttcgta tcaaagcgcc aaacacactc cgagggattt acagaaagca gaaaaggaat
    10981 gatctggtat aagatcattc cttttctctc tttttcttta agtaattata tacaatgtac
    11041 gacgaagtcg tcattgcaat gctgatccac cacctaaagg gaactttaaa caacattgat
    11101 aagataaaga atataaacaa cgaaaatacg ttatacccaa ttaattttat tgtatatctc
    11161 atgattaaaa gttaatcctt ccgttgttag gaatggcatc atttttatcc cataattgtg
    11221 ctaaataagt ccccggtgat aataaattca tagcgaattc taaagcaaca tcatttacaa
    11281 accaactacc tagatatcta gaaattgctg aacgaatagc actttttgct gcatgttttc
    11341 cttttacttt aattagattt gcaaggcctg cagtagttcc tcctaatgct aaagctattg
    11401 cagtatctaa tagagcaccc atttgattaa ctgtaatacc ttgccaagct gctctaaatg
    11461 gagagtatgt aggtgggatt gtataatcgc cttgtaattg tcggttaatt acttctttga
    11521 tccattgttg tgagacgtct ggatgaaaag attggatttc gtttgcaagt gtattgattt
    11581 gttcttctgt tagagaagtg acaggttgaa gttccatatt tgtttcaatt tgtgatactt
    11641 gttcagaagc gtatacagct gaaacacttg gaatcgctga tacaattaac acaattgacg
    11701 tcaaaaaaac cgaaataaat ttcattaatt tgttcatgag cttttctcct ttttatttgt
    11761 atctgcttac attttatcat atactgttat tatagtcaaa aaaatatttt tcaaaatata
    11821 aatggacgga tttattttgg attttatttg ttattttgac ctgcctctat attggtaacc
    11881 atgatttgtt tactctcaat catcaagaat tctcttttcg tggtagcgtt tggggtctgg
    11941 tactggcctt atatcactta ctattcattg ataagtttgt tatatcgaat cgaaaataaa
    12001 gattagagct atgcttgact gtgtactttt aggattgatt ttggaggaag attttgtctc
    12061 tattatttat tattttaaat ttatttattt tgtataagat ctattctttg aggcgggaaa
    12121 aatcgaaata cttgatttat acggcctata tcatatttgg ggtaaatgta gtatatggta
    12181 ttcaatggtt attaaaagaa ctgatttcaa ctatttcccc ttaatgtgta tggaaactat
    12241 aacaaaacgc ataagattaa ggtttgtgta cctgttctta tgcgttttta taatattgaa
    12301 gattttcggt aagttttata cctttgggaa gtctagttta gaatgctttc ccaaccaaaa
    12361 tctctgcttc gatggtaatc tctgtcagtt ggctccagtc aatcttgctc tggtcaacgt
    12421 gaaagaggag aggagtcata ctgagtaggg cttggagttg ttctgctgtg atagtcttag
    12481 tcagagaggc agtttgacta gataggatgg taaagtgttc ctggaaatgc tccttgatat
    12541 cttggttaga atactccttg tttgtcagct ggtcctgtac tctttgacgg atttctttga
    12601 ggtgattttc agttgggata acctttatca agataccgtc tttggataaa acgcgacgaa
    12661 attctccata gttggcaggt gagaagatat caagcagaat atccatgtta gcgtctttta
    12721 taggaaggcg tgccaagtcg ccaacgaacc aattgactgc ccagttgggt tcacttttag
    12781 cagcgatttg gactgaatct ttggagatgt caaaggcata gaaagttttt tcagagtgac
    12841 tttcttgtag tttgcgagaa tagaatcctt caccacaacc gatatccaaa attgttgtgg
    12901 tagtttttga gcttgcaagc aagtcagata cagcatctaa gatagcttgg taaaagccgg
    12961 cttctaggat ttgttgacgg ttttgaaaat tttccttgtc atagttagca gattgcttga
    13021 tttgaggtgc tagattgaca tagccaaatt tcgccaagtc aaaagaatga cggttgcagc
    13081 acttgaaatt agtttctaac agagtcagat tttcttgaca gataggacag gcaaaggcag
    13141 tcgcagaagc aaaacgctga agtttgggtt tgagatttgt attcatagtt taagtgtatc
    13201 aaaagaggca aatgaaagca actttaggaa taagtagatg ggagattcag tagaaataaa
    13261 actaattctc caatttatag aatgaaattg cttttatatc taaattgcta tataataatg
    13321 ataaggagga aataagtatg ttaaaagaag tattaaccgt tgcaaaagtt gcgaaaaaat
    13381 cttcattatt tttgggtggt gtcgcatttg gtacccttgg tttgaaaatc ttagcaagta
    13441 aggaagctaa aaaaggttat tctaaagctt tggctaaggc ttacaagttg aaagacgagc
    13501 tagatgcatc tgtttctgtt gtgaagcaac atggagacga tgtcttgcaa gatgccaaat
    13561 atttgtacga gcaagagaaa aaagaagagc aattagatag ccttataggt gaataatatg
    13621 tcttttaaag tgctacatag aggataccaa catatccgac tatcatcttc tttttcactt
    13681 accttggata ttcaagacta tcttcgttcc ttggcgagag atgaaaaggg gattgagtct
    13741 atccagtttt acatggatca acagcacttt actctacgca taaaagaagg cttttctgta
    13801 ttagataatg cagaagcctt tttaaaaaga attgataaag ggaaagtttc tgagttgatg
    13861 actcttccca ttcgtagaga agagagtgct tattctattg tttcaggtgc agcggttaag
    13921 cgtgtacttt ttcgtagttt tgtgccgtat cctattcgct atatatggac ttgttatcag
    13981 gctttgggtt atattagaga agcctatcaa acactagcgc gtaaggaact aacgatggaa
    14041 gtcttggact gttcggctat tttattgtcc ttgtttatga accaatccaa gacagctagc
    14101 aatatcatgt ttatgcttga tttggggaat catttagatc agtggtcctt gaaaaaaact
    14161 gcaacagatt tagaacagag tcttcttgca aaagagagcg atgtattcct agtacagggc
    14221 gatacggttg ttagtatcaa gagttccgat gttcaaatag gagatgtctt gatcttatct
    14281 caaggaaatg aaattctgtt tgatggacaa gtagtttcag gtttaggtat ggtcaacgaa
    14341 agttccttga caggagagag ttttccagtt gaaaaaagag agtctgattt ggtttgtgca
    14401 aatacagtat tagaaactgg agagttacgc attcgtgtaa cagataatca gatgaacagc
    14461 cgtattttac agctgattga gttgatgaag aaatctgaag aaaacaagaa aacgaaacaa
    14521 cgctatttca tcaagatggc ggataaagtc gtcaaatata atttcttggg ggctgggctg
    14581 acttacctat tgacaggttc tttttctaag gctatttctt tcctattggt cgatttctcc
    14641 tgcgctttga aaatctctac tcctgtagct tatttgacag ttatcaagga agggttgaac
    14701 cgtgaaatgg tgattaagga tggagatgtt ctggagaaat atctggaagt tgatactttc
    14761 ttgtttgata agacaggaac aatcacaact agttatccta tagttgaaaa ggtgttacct
    14821 tttggagact atagtgagga agatattctc agaatcagtg cctgtcttga ggaacacatt
    14881 tatcatccta ttgctaatgc catcgtcaag caagctgaga tagagggaat tgaacatgag
    14941 gaaatgcatg ggaaactcca atatatcgca agcaagggga tcaaatctca tatagatggc
    15001 caaccagttc ttattgggaa ttatgtcttg atgcaggatg agcagattca tatcagttca
    15061 gaacaaaatg ctttaattga agagtacaag agtcactaca atctcttatt cttggcttat
    15121 caaaatgaat tgattggaat gttctgcatt catactcctt tgagaaaaga agcaaaaaca
    15181 gccttggata aacttaaggc acaggggaaa aaattgattc tggcaacagg agacaccttg
    15241 attaggacag aggaattagt caaagatttg ccctttgatc aggtctatac agacttgaaa
    15301 cctgatggga aatttgagtt agtagagaaa ctgcagaaag caggtcacac tattttgatg
    15361 gttggagatg gattgaatga ctcagcggct ttaactctat cagatatcgg tgtggtgatg
    15421 aatgagagtg cagatatttc taagcagatg agtgatatct tattgttaga taatcgtttg
    15481 gatttcttcc aagagttgga ttcgttatca tcatctttgc aaacactcat caagaaaaat
    15541 attcaggata ccgttgtcgt aaatagtagt ttgattggct ttggcttatt taattggttc
    15601 agtccttcaa atctctctat cttacataat ctaacaacct tgcgcattgt cctgcgtagc
    15661 ctgtctatta aaaatagata gatgagagtt attaacagca aaaaggagtt acctttctcg
    15721 aggttaactc ctttgtttat agataaatgt tgaatagttt agtaagtcaa tacaaagtat
    15781 tttttcttcc cacgacggat aacagtcagt tcattttcta acttatcagc gtcactcaag
    15841 acatagtcaa ggtcttggat gcggtcgccg tttacgtaga tggctccgtt ttggacgtct
    15901 tcacgggctt ggcgttttga gttaactata ccagatgaga cgagcagttc cacgatattg
    15961 ttgttttcgt ctgcctgtac ttggtagttt ggcacaccac gaagtccttg tttgagctct
    16021 ttgacagaaa ggtttttgat gtttcctgca aagagttgct cagtgatgtt aagtgcttct
    16081 ttgtaggctt cttctccgtg aacaagtgta acaacttcac gagccaagac tttttgagcc
    16141 aagcgttcgt gtggcgctgc ttcaaattgt ttacgaatat cttcaatctc atcaagtgac
    16201 aagaaagtaa agattttcaa gaagcgaaca gcgtcagcgt ccatcacgtt catccagaat
    16261 tggtacattt cgtatggaga agtcttttcg ggattgagcc agacggcatt tccttctgat
    16321 ttaccaaatt ttttaccagt tgcatctgtg attagtggaa cagtgataac gtgaccagtc
    16381 ttgtccgcct tacgacgaag caattcggta ccagctgtca tatttcccca ctggtcagaa
    16441 ccaccgattt gaagagtgac attatggtct tggttaagga cgaagaagtc gtacccttgc
    16501 atgatttggt aagcgaactc agtgtaagaa attcctgttt cgatccgttt tttaacagat
    16561 tccttactca tcatgtagtt gaccgtgaag tattttccaa tgtcacggag gaagtcaatg
    16621 aagctgatgc tgccaaacca gtcgtagttg ttgaccatga cagccttgtt ttcgccattt
    16681 tcaaagtcaa gaaaacgaga aagttgtcct tggatagact tgacccagcc atctactgtg
    16741 tcttttgttt ggagactacg ttcagcatct ttgaaggacg gatctccgat gagacctgta
    16801 gcaccgccaa cgagcgcata aggtttgtga cctgctagtt gcaagcgacg acttgtcaag
    16861 attgcgacaa ggtggcctag gtgaaggctg tcagcagttg gatcgtagcc agtataataa
    16921 gaaacttgac cttcttctag ggctttacgc aaagcttctt catcagtcgt ttgaaatatc
    16981 aaaccacgct cttttagctc atcaaaaatg tgcatgtgtc ttttctcctt tttaaaatta
    17041 ttgtttctac ctattgtatc acaaacttgg gcaatagcct agcagaatag ggaagaaagt
    17101 ggctatttta ttgaaaattt cccttttgtg gtataataga tagagtgagg aaatccatgc
    17161 aaaatcaatt aaatgaatta aaacgaaaaa tgctggaatt tttccagcaa aaacaaaaaa
    17221 ataaaaaatc agctagacct ggcaagaaag gttcaagtac caaaaaatct aaaaccttag
    17281 ataagtcagc cattttccca gctattttac tgagtataaa agccttattt aacttactct
    17341 ttgtactcgg ttttctagga ggaatgttgg gagttgggat tgctttgggg tacggagtgg
    17401 ccttatttga caaggttcgg gtgcctcaga cagaagaatt ggtgaatcag gtcaaggaca
    17461 tctcttctat ttcagagatt acctattcgg acgggacggt gattgcttcc atagagagtg
    17521 atttgttgcg cacttctatc tcatctgagc aaatttcgga aaatctgaag aaggctatca
    17581 ttgcgacaga agatgaacac tttaaagaac ataagggtgt agtacccaag gcggtgattc
    17641 gtgcgacctt ggggaaattt gtaggtttgg gttcctctag tgggggttca accttgaccc
    17701 agcaactaat taaacagcag gtggttgggg atgcgccgac cttggctcgt aaggcggcag
    17761 agattgtgga tgctcttgcc ttggaacgcg ccatgaataa agatgagatt ttaacgacct
    17821 atctcaatgt ggctcccttt ggccgaaata ataagggaca gaatattgca ggggctcggc
    17881 aagcagctga gggaattttc ggtgtagatg ccagtcagtt gactgttcct caagcagcat
    17941 ttttagcagg acttccacag agtcccatta cttactctcc ttatgaaaat actggggagt
    18001 tgaagagtga tgaagaccta gaaattggct taagacgggc taaggcagtt ctttacagta
    18061 tgtatcgtac aggtgcatta agcaaagacg agtattctca gtacaaggat tatgacctta
    18121 aacaggactt tttaccatcg ggcacggtta caggaatttc acgagactat ttatacttta
    18181 caactttggc agaagctcaa gaacgtatgt atgactatct agctcagaga gacaatgtct
    18241 ccgctaagga gttgaaaaat gaggcaactc agaagtttta tcgagatttg gcagccaagg
    18301 aaattgaaaa tggtggttat aagattacta ctaccataga tcagaaaatt cattctgcca
    18361 tgcaaagtgc ggttgctgat tatggctatc ttttagacga tggaacaggt cgtgtagaag
    18421 tagggaatgt cttgatggac aaccaaacag gtgctattct aggctttgta ggtggtcgta
    18481 attatcaaga aaatcaaaat aatcatgcct ttgataccaa acgttcgcca gcttctacta
    18541 ccaagccctt gctggcctac ggtattgcta ttgaccaggg cttgatggga agtgaaacga
    18601 ttctatctaa ctatccaaca aactttgcta atggcaatcc gattatgtat gctaatagca
    18661 agggaacagg aatgatgacc ttgggagaag ctctgaacta ttcatggaat atccctgctt
    18721 actggaccta tcgtatgctc cgtgaaaagg gtgttgatgt caagggttat atggaaaaga
    18781 tgggttacga gattcctgag tacggtattg agagcttgcc aatgggtggt ggtattgaag
    18841 tcacagttgc ccagcatacc aatggctatc agaccttagc taataatgga gtttatcatc
    18901 agaagcatgt gatttcaaag attgaagcag cagatggtag agtggtgtat gagtatcagg
    18961 ataaaccgat tcaagtctat tcaaaagcta ctgcgacgat tatgcaggga ttgctacgag
    19021 aagttctatc ttctcgtgtg acaacaacct tcaagtctaa cctgacttct ttaaatccta
    19081 ctctggctaa tgcagattgg attgggaaga ctggtacaac caaccaagac gaaaatatgt
    19141 ggctcatgct ttcgacacct agattaaccc taggtggctg gattgggcat gatgataatc
    19201 attcattgtc acgtagagca ggttattcta ataactctaa ttacatggct catctggtaa
    19261 atgcgattca gcaagcttcc ccaagcattt gggggaacga gcgctttgct ttagatccta
    19321 gtgtagtgaa atcggaagtc ttgaaatcaa caggtcaaaa accagggaag gtttctgttg
    19381 aaggaaaaga agtagaggtc acaggttcga ctgttaccag ctattgggct aataagtcag
    19441 gagcgtcagc gacaagttat cgctttgcta ttggcggaag tgatgcggat tatcagaatg
    19501 cttggtctag tattgtgggg agtctaccaa ctccatccag ctccagcagt tcaagtagta
    19561 gttctagcga tagcagtaac tcaagtacta cacgaccttc ttcttcaagg gcgagacgat
    19621 aattctctaa atgaagtggc caatcaatgg attgccactt ttttcctttc gtgttacaat
    19681 aagggtatga atcagtatca gaaaaagatt gttaacggaa aaatttattc gctcctatcc
    19741 ggcttaatat ggggaatctg tggaatttta ggagagtact tctttactca ttatcaggtg
    19801 tcttcgggct ggattacctc tatgcgtttg acactggcag ggagtattgt actcatttgg
    19861 tctgcaatac aattaaaatc gcaagtgcta gatatttggc gagacaagaa aaattacctg
    19921 ccctttttag cctatgctat tttggggatt ttttcagtcc agtatttttt ctatctctgt
    19981 gtagaatact caaatgctac gacagcaact attttacagt ttattagccc tgtctttatc
    20041 ctcttttaca atcgcttggt ttatcaaaaa cgagcgtcaa aaagcgctgt tttctatgtt
    20101 ttggttgcca tgctgggtgt ttgcttgatg gcgacaaagg gagatctctc tcagttatcc
    20161 atgacgccgc tagctcttat aacaggtttg ctgagtgcca tgggtgttat gtttaatgtt
    20221 atcttgcccc aaccttttgc taagcgttat ggttttgttc ctacggttgg gtgggggatg
    20281 attttggcag gtttgtttag caatgtcctc tcgccggttt atcagctttc ctttactctt
    20341 gatatttgga gtatcttgat ttgcctcatt atcgctttct ttggaacggc ttttgctttt
    20401 ttcatttcca tgaaggctgt gtccttggtt tctcctttgg tggttgccgt tatcagtgcc
    20461 agtgaacctc tctcttctgc tctcttgagt gttttgttct taggattagt agtggattgg
    20521 tccctccttc tagctatagt cttgattatt ttacccatga tatttttgtc tatagaagaa
    20581 gcgaaagaaa gtagataaaa agtcttttct taattctaaa agtgtgctat actagaatag
    20641 tcaataaaac acggggagat agttgtgaag agtgttttta ggttgtatcg gtaggggctt
    20701 gcttttaccg acagcacgtt ttatctcaca accctaaaaa atcataccta aaaacagaca
    20761 aaaaggtttc aaatttgagg ccttttttgg tagaataggt atcattataa cgaaccagga
    20821 ggcacctatg actgctacaa aaatgaacgc tcaagaaatt atccaattta tcgccaatgc
    20881 tgaaaagaaa accagtgtca aagtaacctt tgaggggcaa ctcgcaactg ctgtgcctag
    20941 ctctgttgtc aaactaggaa atgtcctatt cggagactgg aaggacgtgg ctccgcttct
    21001 tgaaggtttg gtagaaaatc aagattatgt tgtcgagcaa gatgctcgta attctgcagt
    21061 tcctttgcta gataagcgtg ctatcaacgc tcgtatcgag ccaggtgcta ttatccgtga
    21121 ccaggtggaa attggtgaca atgctgttat catgatggga gctgttatca atatcggtgc
    21181 tgaaatcggt gctggaacca tgattgacat gggtgccatc cttggtggcc gtgccatcgt
    21241 tggaaaaaat agccacgttg gtgcaggtgc agttttggca ggtgtgattg agccagctag
    21301 tgctgaacca gtccgtgtcg gagacaatgt tcttatcggg gctaatgcag tggttatcga
    21361 aggagtccaa atcggtagtg gttcagttgt cgctgcagga gctatcgtta cccaagatgt
    21421 cccagaaaac gtggtagtag caggtgttcc agctcgtatc atcaaagaaa ttgatgccca
    21481 aacccaacaa aaaacagcgc tagaggatgc gcttcgtacc ttgtaattgt aaaagtaaaa
    21541 aagaggcgga accctttttc cagcctcttt ctgctatatc ggaggacaga tagatgttag
    21601 atttgattca gactagacga gctttacacc agattccaga gattggcttg gaggagttca
    21661 agactcaggc ttatttgctg gatgtgattg agaaattgac tacgggcaag gattttgttc
    21721 aaattcgtac ttggcggaca gggattttgg cctacctgca gggaagtcag ccggagcgaa
    21781 ccattggttg gcggacagat attgatggcc tgcctatcgt cgaacaaaca ggtctacctt
    21841 ttacttctca acaccaaggt cgcatgcatg cctgtggtca tgattttcat atgaccattg
    21901 ccttaggctg tcttgagcgc gcccttgagg agcaacccaa gaataatctg ctctttctat
    21961 ttcagcctgc tgaagaaaat gaagctggtg gtatgctcat gtatgaggac ggtgcttttg
    22021 gagattggtt gccagatcaa ttctatggtc tccatgttcg tccagatttg aaagtcggcc
    22081 agattgcgac taatactcat acactctttg caggaacttg cgaggtgaag atccgtttca
    22141 aaggtaaagg tggccacgca gcttttcctc atgaagccaa tgacgccttg gtggcggcta
    22201 gttactttgt gacccaagtg cagtcagttg ttagccgcaa tgtcaaccca atcgagggag
    22261 cagtggtgac cttcggcgtt tttcaagctg gaaccaccaa caatgtcatc acagacacag
    22321 cttttttaca tggaactatt cgtgccttga cacaggacat gagtctcttg gtgcaaaaga
    22381 gggtaaaaac agttgcagaa ggggttgcag ctgcctttga tatggaagtc gaagtggaac
    22441 tcaaacaagg tggataccta cctgttgaga acaatccagc cttggcgcgt gaactgatgg
    22501 acttctttga cgagaaagac ggaatcgagt tgattgatat cgaacctgct atgacaggcg
    22561 aggactttgg ttatctcctt tcaaaggttg atggcgtgat gttttggcta ggtatcgata
    22621 gtccctacgc tcttcatcac cctcaaatga gtcctaagga agaagtctta gctattgggg
    22681 tggctgcggt gtctagtttc ctgaaaaaga aggcagcaga atagagggct tgtctatgaa
    22741 atcggaatta cgcaagcaag tcttgcatga aatgaaggct atatctcaag agcaaaaaca
    22801 ggctatagac caagctttaa ccgagcgaat tttacaacac cccttttatc aagaagccaa
    22861 ggtcatcgca acctacctct ctttttctca tgagtttcaa acgcgggaac tgattgagca
    22921 ggcgctgaag gacggcaaga aggttttgac acctaagacc tatcccaagg ggcgcatgga
    22981 ttttgtggtc tatgatccgc aacagttggt aaaaacttcc tttggattac tggagccaca
    23041 gggagatttg gaagttgtgg atgtttcaaa gattgatttg attcatgttc ctggtctggc
    23101 ttttacgaca aaaggatatc ggataggata cggtggaggc tattatgacc gctatctgga
    23161 acatttttct ggtcgtgctt tgagtacgat atatccttgt caaattcagg actttatacc
    23221 tgaaaaccat gatattcctg ttcaggaggt attaattgat gaaggaaatc tttgatagac
    23281 gttaccctgt gacgagtttc ttcctcttag tgacggcctt ggtattttta ctaatgttgg
    23341 tcactgcagg cggaaacttt gacagggcag atacattatt tcgatttgga gccatgtatg
    23401 ggtcagctat tcgcctcttt cccgagcagg tttggcgtct cttgtctgcc atttttgttc
    23461 atattgggtg ggaacatttc attgttaata tgctttcact ttattatctt ggaaggcagg
    23521 tagaggagat tttcggttct aagcagtttt tctttctcta tcttttatca ggaatgatgg
    23581 gcaatctctt tgtttttgta tttagtccta aatccttagc agcaggcgcc tctacctctc
    23641 tttatgggct atttgccgcg attattgttc ttcgctatgc aactcgcaat ccttatatcc
    23701 aacagctagg gcaatcctat ctgacacttt ttgtggttaa cattattgga agtgttctga
    23761 ttccaggaat cagcctagca ggccatatcg gtggtgcagt tggtggcgca tttctagcag
    23821 ttatctttcc agttagagga gaaaaacgga tgtataatac cagccagaga ttaggagcgg
    23881 tagtcttgtt cgtaggactc gccattttgc ttttctacaa gggaatggga atgtgacgaa
    23941 gttgaaagaa aatttgtgta atgaaaaaag ataaggcatt ttttgaacct tatcttttta
    24001 ttttatttta ttccttctca gtcaattctt ttccaagttg gatgaggtaa ttcttcaaat
    24061 catctttgac ttgtgggtgt ttgagggcgt agtcgatgga tgttttcatg aagccaaact
    24121 tgtctccgac atcgtaacga gccccattga actcacgagc aaatacacgt tgtgttttat
    24181 tgagggtgtc gattgcatct gtcagctgaa tttcatttcc tgcacctgga gcttggtttt
    24241 cgaggatttg gaaaatttca ggcgtgagga ggtagcgtcc gataatagca aggtcgctag
    24301 gagcgtcctc tggagctggt ttttcaacaa aggtttcaac actgtaaaga ccattttttc
    24361 cttcgccttg cggagcaata accccgtaag cagatacttc gtcatgaggg actggcatga
    24421 cagcgatagt agacgcgtgg gtacgctcgt agtcatccat gagttgtttg gtaagtggaa
    24481 cagccttttc gtctgtgata tccatcaagt catcaccaag cataacgaca aaaggttcat
    24541 ttccgacgaa agccttggct tgcaaaacag catctccgag accgcgtgga tgagtttggc
    24601 ggataaaatg cagacgcatg tcagttgttt tatcaactag cttcaaaaga tctgttttcc
    24661 ctttttcttt gaggttatat tccaattcga agtttgaatc aaagtggtcc tcaatagaac
    24721 gttttgattt accagtgaca actagaatat cttcaatacc tgatttgaga gcttcttcca
    24781 cgataaactg gatagttggt ttgtctacga ttggcaacat ttctttggca agggccttgg
    24841 ttgctggtaa aaatcgagtt cctagtccag cagcagggat aactgccttt ctaacttttg
    24901 atgtcataaa aatcctttct atagagggtt aagaccactc attttctgct ttaaattcat
    24961 tgttcatgat gtcataaatg gcatctttga tattggttcc gtgataaata acttggtaaa
    25021 tagcctgtgt aatgggcata tagactccaa gttcttgggc tagttcatag gctgctcgag
    25081 tcgttgaaat tccttcgatt accatgccca tattagcttc tatatcagct agggattctc
    25141 ctcgtccgag agcatctcca gctctccagt tacgagagtg gatggaagtt cccgttacga
    25201 tcaaatctcc cacaccagat aagccgctat aggtcaatgg actggccccg agtgctaccc
    25261 ctaggcgggt gatttctgct aaacctcgag cgatgatggc tgccttagca ttatcaccaa
    25321 atccaagacc atgtaaagct ccagcaccga cagcaataat atttttaaga gcaccagcag
    25381 tttcaacccc gataacatcc gtattggtat aaagtcggaa gtagtgatta ctaaatagct
    25441 tctgaacgta ttgagctgtt tgtaaatctt tagaagcagc agttattaaa gttaggtcac
    25501 gcacaatggt ctcttctgca tgactaggcc ctgaaacaac gacgatatca ctacggagat
    25561 gttcaggaat ttcttcttca agaatggttg ataatcgttt atggctatca ggttctaatc
    25621 cctttgatgc gtgcatgatg ataaccttat ggtccaaggt ttgtgcaact tgttgggcaa
    25681 caagtcgtgt cacttttgtt gggacaacaa acaaaatcgc atccacatct ttcaatgttt
    25741 ctgctaagtc ggtgtaggca atgatatttt cgtctagaac gacatcttta aagtagtgct
    25801 tattagtatg gtgtgtatta atttcattga tttgctcggg aagatttccc caaatacgta
    25861 cctcgtgtcc attgtcattt aagacttgtg aaagggcggt tccccaagaa ccaggcccca
    25921 agacggcgac ggtttgtttt tccatgattt cctccttgat agagttcttt ctcttattct
    25981 atcatattct aggggatttt gcacttgcat tactggggta tggtggaaaa atacacaaaa
    26041 accgagacga agggataaac tcttagtctt tagttaaagt gagaagaaat ctgatagata
    26101 gtttgattca gtatatgctt ataatagagg taaacaactc aggaggttct tgtaggttgc
    26161 gagagtttgg cgaaaaaatt aaaagattac gtttggctaa aaaaatcagt cgttcagaat
    26221 tttgtggtga tgagtctgaa ttaagtatcc gtcaattaat tagaattgaa aatggagaat
    26281 ccagaccaat actaacaaag ttaaaatata ttgctgaacg tttgggggtt gaagattaca
    26341 agttgatgcc aagttatata gagttggata aggaatacct agaattgaag tatttcttga
    26401 tgaggactcc tacatacgaa gatgaaacta tcgcccaaaa gaaagagagt gtttttgata
    26461 agatttttga agagtattat gataggctac ctgaggaaga aagatttatc atcccaaatt
    26521 attcatatct ggcactaacg aactatacag ttcaaaaatt accagaaaag ctagttgaaa
    26581 tactgtcctt ctggtgattt tgcttaattt ctgatgttcg agacatgatt gaggagattt
    26641 gtcttgattt tttcctaaaa aagggcagac tcctcccttg gtttgatgct cgatttttaa
    26701 aataaggtga cttattctgt taggcatgtt ttcccctgcc ctctagcttt atatggaaca
    26761 gggagtatca gatttatctg gcagattgta tcaaataagg cttgaaactg ttttgaatag
    26821 gcgtatagac ttgagaattt gagaatatgt cgtctagcag tagagacata ttttccggca
    26881 atatgaagga agagacgtcg aaaacgcttg atagtcaagg cctttacttc atcaccagct
    26941 agctgcttta aaaagaggta gagattataa gccagacagc ccatcatcat acgtacttca
    27001 ttcttaatca tggtcgaact atctgtctta tccccaaaga atcctgcttt cctttctttg
    27061 ataaagtttt cagcattccc tcgttcacga tagaattgaa acagctcctc actatctaca
    27121 ctgcttaaat tggtcaaatg aactttttta caaccataaa aaagagcact taatcgtact
    27181 cttctctttt aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta
    27241 gactaggcgt tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat
    27301 ataaaggtat tgtgttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat
    27361 ttcctttgat aaggcataat aatattggtc aatctgttca tctttttgag caatactaat
    27421 agcttttgag gcttggtgca aaggaaaggc aaccaataaa tcggctagca tgctgaggga
    27481 taatttaccc atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg
    27541 caaaacagct ttagcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga
    27601 agacatgatg ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa
    27661 acgggcacag gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat
    27721 aattagctct gccatctcct tgtctttgga ggctaaggcc agtaaggctt ttgaagctgt
    27781 ttcaaggaca agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc
    27841 aaattgattt ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct
    27901 gtgcgctgat cttttggatt ggtaaacacg tcaacggtat ctccaaattc gcaaatttct
    27961 cctgttaaga aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta
    28021 acaatgataa tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg
    28081 gagatagggt ctaaggctga agtcggctca tccattaaca gaacatcagg ttctactgct
    28141 aaagctcgcg caatgcaaag gcgttgctgc tgaccgcctg ataaggacat ggcactcttt
    28201 ttaagattat ctttgacttc gtcccaaatg gctgcccctt ttaaagattt ttccactaag
    28261 gcatctaatt gttttttgtc tcgaatacca tgtgtccttg ggccataagc cacgttatca
    28321 tagatagaca tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttgcgtagc
    28381 tgattaaggt tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca
    28441 atatggcaag aaggaaccaa atcgttcatc cgattaaggg tttttagaaa agttgatttg
    28501 ccacaaccag atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata
    28561 ttttttaagg cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc
    28621 atactaggaa gctcctttca caagtttccg agataataag cttgatagag tatttatcat
    28681 taaaacagta ataattaaaa tcacgccggt agcataggct tcattgacat gtagcccctc
    28741 acttgacagc atatacatat gtagggctag agaacggcct gaagacatga gactacttgg
    28801 cgtattggta gaggtaccta atgtatacat gagggcagct gtttcaccaa cgatacggcc
    28861 aatagctagt atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa
    28921 aacagtccgt aacttacctg ccccaagtcc ataacttgct tgacgcatgc tatcactaac
    28981 agataaaagg gcttcttctg ttgagcgaat aatgactggc aacaccatga taactgaggt
    29041 taagattcct gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc
    29101 aaacagacca aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcatgat
    29161 tttaacacaa agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc
    29221 tatgggcaag gctaaaagaa gagcaccaaa gaccagaata acggtggaaa taatcgctgg
    29281 cataagggaa atattctcag aagtataagt ccaagaaaag agggatagac ttagatgagg
    29341 taagcctttg atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga
    29401 aaaacaataa acgagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt
    29461 aggcaaagta ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa
    29521 gggcttccct atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg
    29581 ttctggttcc tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa
    29641 ctgccatggt ttcacctact gcgcgaccaa ttcctaaaat aactgctgat aaaataccag
    29701 atctcgcagc tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca
    29761 agctaccaga ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa
    29821 tggttggcaa aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc
    29881 ctaaaaaggt tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag
    29941 atggaatggc cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac
    30001 aataataaac cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc
    30061 ctaaggtaat taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt
    30121 tcgttggcga ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag
    30181 gtaagccatt actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg
    30241 cactcatgaa aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt gtcacatctt
    30301 gtcctttcta gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct
    30361 tattgtacga tgaaacgtct gcatctcttt agagatttat ggagcaaaca ttttatttaa
    30421 tcttgtccca ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt
    30481 ggcttgcctt attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat
    30541 gggtgagact tttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg
    30601 ttttctcctt aacagcggta atacctgctg aagacccatt agaggtaata tcaatcgtaa
    30661 cttctggatt ttctttttta taagcttctg ctaatttttc cattaaagaa gatactgaag
    30721 tggaacctac aacagacaac ttgcctgata agtgttggct tgtatattct gtggtttcgg
    30781 ttttagcttc aataaattta ttatctgtga ccacttgttg accttgtttg gagtggataa
    30841 agctgataaa atcttgacct agcttggaaa gattagaaga ccaaacaatg ttgaagggac
    30901 gttgaagagg gtattcacca tctaaaactg tgtctcgact agccttgaca ccatcaatct
    30961 ctaaagcctt gacagatttc gttaaagatc ccaaggagat gtagccgata gcattagcat
    31021 tcccttgaac tgctgagaga acaccttctg tactattttg aatcacagct gttttggcag
    31081 tgttgtcaat ttttttatca ccgtcttttt tgagaatccc tgtgatttct gtgaaggcac
    31141 cccgtgttcc agagccattt tctcgtgaaa tcacctcaat cgttcctgaa gctgactgtt
    31201 tggaagcagc tgactgattg ccacaggcaa caagcccaaa tcctgataag ccaatggctg
    31261 caagagtaag catttttttg aatttcataa taatcacctt tatctctatg tatttttctt
    31321 gtgtaggctt actacattta tagtctaaca agtctttgta aaggtttatc cctgattcat
    31381 gtaaagattg tgtaaagaat caaaaaaagc cacttttgaa aaatggctgc tcctaaaaat
    31441 agctttaaaa attattagtc ctgtgcgaaa gattggttag gaagaaaaat cgtgaagcaa
    31501 ctgcctctgc caagctgact cgtcaccgtg acttggccac ttaataattg actgagttct
    31561 ttgacaatgg caaggccaag accagtgcca ccagtttgtc tgcttcgacc tttattaact
    31621 cggtaaaaac gttcaaaaat acgatcctgc tctaattgac taataccaat ccctgtatct
    31681 gatacagaaa tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat ttttccccct
    31741 tgttcagtgt aacggatggc attggataaa agattgagta agatttggga aagtaattga
    31801 ctatctgata cgagggtgac atcatctggc acctgcacct ttagctgtaa atccttcttc
    31861 ttgagctgag gttgcaagct ttgagtcaaa tcctgtacaa attctgccaa agaaagggtc
    31921 gtccattgta taggcatttg ttgagcctta gataaggtaa gaagatgctc aacaatatgc
    31981 tcaagacgca aactttcttt gtaaataatg tctagaaagt catccttgag cgcttcttct
    32041 tcagctgaca tccccttaat ggtttcagca aagcccttaa tcgaagtaac tggtgtcctc
    32101 aattcatggg aggcatttga gacaaaggct aaatttaact tttcataagt tctaatcgtt
    32161 gttaaatcat atagcaagac gagcacagct tccacagatt gggtggggct aaaaacggga
    32221 actgctgtca cttctaaaat caagtcaccc tcatgaaacc cacttacttc ttgttttaac
    32281 cttgtttttt gatcaaaggc ttggtgaact aaatttcgaa tatccatccg tttgaggtca
    32341 tcaagtgaac ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga gcgactggat
    32401 aataacatct gaccttgagc ggaaactaaa aacgtcccca tggttaggtg cgacagaaga
    32461 acctccattg tttcggctag gtccttgtat tgctgatcct gttgggagac tttggttttt
    32521 agggcagaca catactgagc caaagacttt aagtcttctt gccctttttc taaaaagtat
    32581 tcactactgg tcaagagagg ttggtgcaag gtctcaaaag caacttccca tttccaaagg
    32641 caaaagagcc agtagccacc tagtcccaaa gaaagggcta gaagaaagag accgatgcct
    32701 ttactgatcc aagttaatgc catccctgca atcagaatga ggctaacact tagattgact
    32761 agccaaaatt gaaggtagcg tttcatctat aactccttga acttataacc atacccccga
    32821 atggttcgaa taaattgagg ggctttagga ttgtcttcaa ttttttccct taacttacca
    32881 atatgaacgt ccaccaaacg tgtttcctgc ccaaagtcat acccccagat acgttccaaa
    32941 agacgctctc tagtcagtgt catgttggga tgtttcataa gatagagcaa gagttcaaat
    33001 tcttttgggg tcaaactcag taacttattc gccttgtaga cttcatgacg ctcagggtat
    33061 actttcaagg tcccaaatag ccaagaatcg tcagcgatat tatctgaatc atctccttct
    33121 tgttctcctt tagttcgcct gagaacagcc ttgacacgcg ccagcaattc tctagggcta
    33181 aaaggcttgg tcaggtagtc atcagcccct aattccaagg ccaaaacctt atcaaattca
    33241 tcacttttcg cagaaaccat cataattgga gttttgacgc ctttggctct cagccgctta
    33301 caaacttcca tgccatctaa ttgtggtaac atgatatcaa gcaagataaa atcaaagggt
    33361 tctgtttctg ccaaagctaa ggccttccgt ccatttgtta ccaattgagt agaaaagcct
    33421 tccttactta aatggtagtc aagcaatttc agaatgtgtt cttcatcatc cactaataag
    33481 acttgttttg tcatctatta tctcctattg gtaacattat aacacaatta tcagaaatcc
    33541 taacattgct aaatcagatt aaatttgctt atcaagacta gtatctggtc aaacgctcaa
    33601 tcatctcctt gtgctctgga taggtcgcca gtagatctac cctttcaaat aattcaaaat
    33661 cctcaaattc aaaaccagga gcaacaagac aagaaaccag agcatcatcc ttatcaactg
    33721 ttgatcccca aatagtgccc ttaggaacac agtagtgaag ttgttgccct ttggatatgt
    33781 ccaggcctaa agtgactgct tcgtagtgac catctgctgt aatcatgtga acagtaagtg
    33841 gggattctgc atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa tgtgaaggat
    33901 tcgtttcttc ttaataagaa ataaatactg gtataaagcg cccttccctt accagcaagg
    33961 tttatagtgt ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac atggggagct
    34021 aactctagag ttcttatcaa gtcttcttta tccgtcggag ccaatgggtt gaagtaactc
    34081 ttgttcaaag tggtgttacg atttcaagaa ctcctctcag ttctgaggac acggtaatga
    34141 ttgatgcgac ggaagtacaa atcaatcgcc ctaaaagaag aattagcgaa tgattctggt
    34201 aaaaaaaatg ccacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt
    34261 ctttggatat cgctgtgaac tattgtcatg atatgaagtt gttcaaaatg agtcgcagaa
    34321 atatcggaca agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat
    34381 atcctcaagc acaaactcca cgtaaatcca gcaaactcaa gccactaaca gttgaagata
    34441 aagcctataa ccatgcgcta tccaaggaga gaagcaaggt tgagaacatc tttgccaaag
    34501 taaaaacgtt taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc ttcggattac
    34561 gaatgaattt gattgctggt attatcaatc atgaactagg attctagttt tgcaggaagt
    34621 ctattatttg gttaggtgaa ttagtgaagt gtttaggcaa gtgtctctgg ttacgacgtc
    34681 atggcctcta aatcgattat atttaggggt catgactagt gaagcagtta gctagttcgc
    34741 atataagcgg ctagcgtcta acaattagga actttagttc caataacttt aagattacga
    34801 cgttttagga cataaatcga tcatatttat gtcctaaaac tagtgaagcg cctagccaaa
    34861 gtccgaatag gatttggcgt tagttactta gattgctttg caatcaagta actttggcga
    34921 tttacatctt ctctggcgct tctactccaa gcaagcgaag ggcttctttg agaacgactg
    34981 cggttgcgta gctgagggct agacggctgt cgcgttctgg gctttcatcc aagatacgtg
    35041 tatgtgcata gtatttgtta aaggattgag ccaggctaat tgcaaattta gcaatgatag
    35101 aaggttcaaa gttatctgcc gcacggttga taatacgtgg gaagtcttga atgagtttaa
    35161 tgatttccca gctttcagta tcattcaagc tatagttgcc agctgtttct ggtttgaaat
    35221 cggctttgcg taagatagat tggatacgag cgtaggcata ttgaacgtaa ggtccagttt
    35281 caccctcgaa ggataccata gcctctaggt cgaagtcgta tccatttgta cggtcggttt
    35341 tgaggtcata gaatttaatg gctccaaccc caacagcatg tgctacctga tctttatttt
    35401 ccaattcagg atttttagcc tcgatttgga ccttggcacg gctaacagcc tctgcaacag
    35461 taggctctag caagatgaca ttccctttac gagtagagag cttcttccct tcttttgtaa
    35521 ccagaccaaa aggaacgtgg gtaatgtcgt cactccaatc gtagcccatc tcttgcaaga
    35581 cagctttgag ctgtttaaag tgggcagatt gttcttgacc aacgacatag atagatttag
    35641 caaattggta ttcgttttta cggtagaggg ctgcagccaa gtcacgtgtg atatagagag
    35701 ttgcaccatc agacttcttg atgagggctg gatgttcaat tccatatttc tcaagattca
    35761 caacttgggc accttctgat tcaagaagta gtcctttttc agaaagaatg tctacaactg
    35821 catccatctt atcattgtag aaggcttctc cgttatagct gtcaaattca accttcaatt
    35881 cattgtaaag gcggttaaat tccactaaac tttcatcgcg gaaccattgc caaagagcga
    35941 gagcttcctc atctccattt tcaagtttac ggaaccattc gcgcgcttct tcatccaagc
    36001 tagggtcatt ttcagcttca gcgttgatgc ggacatagag tttaaggagt tcatcgattg
    36061 gatgagcttt tacagcttct tcgtcgcccc attttttgta ggcaacaatc aacatcccaa
    36121 attgtttacc ccagtctccc aaatggttga ccttgaccgt ttgataaccg attttttgga
    36181 aaatatgtga caagctatct ccgataacag ttgaacgcag gtggccaata gaaaatggtt
    36241 tagcgatatt cggactagac atgtcgataa caacattttc ttgtttacca atattttggt
    36301 cagcatagtg ttctttttca gtggtaacag cttgcaatac ttgagcagaa atggcagatt
    36361 tatcaaggaa aaagttaacg taaggtcctg ttgcgacaac tttttcaaag gcttggctgt
    36421 tcattttttc agccagttca gccgcaatca tttgtggtgc tttacgttcg actttggcaa
    36481 gagaaaaagc agggaaagcg atgtcaccca tttctgagtt tttaggggtt tccagtaact
    36541 ttaaaatagc ctcttggtcc aggctatcaa tgatgctagc caattcgcta gcaatcaatt
    36601 cttttgtatt cattaagagc tcctttttgg acttttctac tattttatca caattttaaa
    36661 gaaagaagaa aaaatttttg aaatctcctg tttttttggt ataatatggt tataaatata
    36721 gttataaata tgcacgcaag aggattttat gagaaaaaga gatcgtcatc agttaataaa
    36781 aaaaatgatt actgaggaga aattaagtac acaaaaagaa attcaagatc ggttggaggc
    36841 gcacaatgtt tgtgtgacgc agacaacctt gtctcgtgat ttgcgcgaaa tcggcttgac
    36901 caaggtcaag aaaaatgata tggtgtatta tgtactagta aatgagacag aaaagattga
    36961 tttggtggaa tttttgtctc atcatttaga aggtgttgca agagcagagt ttaccttggt
    37021 gcttcatacc aaattgggag aagcctctgt tttggcaaat attgtagatg taaacaagga
    37081 tgaatggatt ttaggaacag ttgctggtgc caatacctta ttggttattt gtcgagatca
    37141 gcacgttgcc aaactcatgg aagatcgttt gctagatttg atgaaagata agtaaggtct
    37201 tgggagttgc tctcaagact tatttttgaa aaggagagac agaaaatggc gatagaaaag
    37261 ctatcacccg gcatgcaaca gtatgtggat attaaaaagc aatatccaga tgcttttttg
    37321 ctctttcgga tgggtgattt ttatgaatta ttttatgagg atgcggtcaa tgctgcgcag
    37381 attctggaaa tttccttaac gagtcgcaac aagaatgccg acaatccgat ccctatggcg
    37441 ggtgttccct atcattctgc ccaacagtat atcgatgtct tgattgagca gggttataag
    37501 gtggctatcg cagagcagat ggaagatcct aaacaagcag ttggggttgt taaacgagag
    37561 gttgttcagg tcattacgcc agggacagtg gtcgatagca gtaagccgga cagtcagaat
    37621 aattttttgg ttgccataga ccgcgaaggc aatcaatttg gcctagctta tatggatttg
    37681 gtgacgggtg acttttatgt gacaggtctt ttggatttca cgctggtttg tggggaaatc
    37741 cgtaacctca aggctcgaga agtggtgttg ggttatgact tgtctgagga agaagaacaa
    37801 atcctcagcc gccagatgaa tctggtactc tcttatgaaa aagaaagctt tgaagacctt
    37861 catttattgg atttgcgatt ggcaacggtg gagcaaacgg catctagtaa gctgctccag
    37921 tatgttcatc ggactcagat gagggaattg aaccacctca aacctgttat ccgctacgaa
    37981 attaaggatt tcttgcagat ggattatgcg accaaggcta gtctggattt ggttgagaat
    38041 gctcgctcag gtaagaaaca aggcagtctt ttctggcttt tggatgaaac caaaacggct
    38101 atggggatgc gtctcttgcg ttcttggatt catcgcccct tgattgataa ggaacgaatc
    38161 gtccaacgtc aagaagtagt gcaggtcttt ctcgaccatt tctttgagcg tagtgacttg
    38221 acagacagtc tcaagggtgt ttatgacatt gagcgcttgg ctagtcgtgt ttcttttggc
    38281 aaaaccaatc caaaggatct cttgcagttg gcgactacct tgtctagtgt gccacggatt
    38341 cgtgcgattt tagaagggat ggagcaacct actctagcct atctcatcgc acaactggat
    38401 gcaatccctg agttggagag tttgattagc gcagcgattg ctcctgaagc tcctcatgtg
    38461 attacagatg ggggaattat ccggactgga tttgatgaga ctttagacaa gtatcgttgc
    38521 gttctcagag aagggactag ctggattgct gagattgagg ctaaggagcg agaaaactct
    38581 ggtatcagca cgctcaagat tgactacaat aaaaaggatg gctactattt tcatgtgacc
    38641 aattcgcaac taggaaatgt gccagcccac tttttccgca aggcgacgct gaaaaactca
    38701 gaacgctttg gaaccgaaga attagcccgt atcgagggag atatgcttga ggcgcgtgag
    38761 aagtcagcca acctcgaata cgaaatattt atgcgcattc gtgaagaggt cggcaagtac
    38821 atccagcgtt tacaagctct agcccaagga attgcgacgg ttgatgtctt acagagtctg
    38881 gcggttgtgg ctgaaaccca gcatttgatt cgacctgagt ttggtgacga ttcacaaatt
    38941 gatatccgga aagggcgcca tgctgtcgtt gaaaaggtta tgggggctca gacctatatt
    39001 ccaaatacga ttcagatggc agaagatacc agtattcaac tgattacagg gccaaacatg
    39061 agtgggaagt ctacctatat gcgtcagtta gccatgacgg cggttatggc ccagctgggt
    39121 tcctatgttc ctgctgaaag cgcccattta ccgatttttg atgcgatttt tacccgtatc
    39181 ggagcagcag atgacttggt ttcgggtcag tcaaccttta tggtggagat gatggaggcc
    39241 aataatgcca tttcgcatgc gaccaagaac tctctcattc tctttgatga attgggacgt
    39301 ggaactgcaa cttatgacgg gatggctctt gctcagtcca tcatcgaata tatccatgag
    39361 cacatcggag ctaagaccct ctttgcgacc cactaccatg agttgactag tctggagtct
    39421 agtttacaac acttggtcaa tgtccacgtg gcaactttgg agcaggatgg gcaggtcacc
    39481 ttccttcaca agattgaacc gggaccagct gataaatcct acggtatcca tgttgccaag
    39541 attgctggct tgccagcaga ccttttagca agggcggata agattttgac tcagctagag
    39601 aatcaaggaa cagagagtcc tcctcccatg agacaaacta gtgctgtcac tgaacagatt
    39661 tcactctttg atagggcaga agagcatcct atcctagcag aattagctaa actggatgtg
    39721 tataatatga cacctatgca ggttatgaat gtcttagtag agttaaaaca gaaactataa
    39781 aaccaagact cactagttaa tctagctgta tcaaggagac ttctttgaca attctccact
    39841 tttttgctag aataacatca cacaaacaga atgaaaagga gctgacgcat tgtcgctccc
    39901 ttttgtctat tttttaagga gaaagtatgc tgattcagaa aataaaaacc tacaagtggc
    39961 aggccctggc ttcgctcctg atgacaggct tgatggttgc tagttcactt ctgcaaccgc
    40021 gttatctgca ggaagtctta ggcgccctcc ttactgggaa atatgaagtt atttatagta
    40081 tcgggacttg gttgattggt gtggccgtag tcggtctagt tgctggtgga ctcaatgttg
    40141 tcctcgcagc ctatattgcc caaggagttt catccgacct tcgggaggat gccttccgta
    40201 aaattcaaac tttttcttat gctgatattg aacaatttaa tgcgggaaat ctagtcgttc
    40261 gaatgacaaa tgatatcaac cagattcaga acgttgtcat gatgaccttc caaattcttt
    40321 tcagacttcc cctcttgttc atcggttcgt ttatcctagc gcttcaaacc ttaccttctc
    40381 tgtggtgggt gattgttctc atggtagtct tgatttttgg tttgactgct gtcatgatgg
    40441 gaatgatggg gcctcgtttt gctaaatttc aaacccttct tgagcgcatc aatgccattg
    40501 ccaaggaaaa tttacgtggc gttcgtgtgg tcaagtcctt tgtccaagaa aaagagcaat
    40561 ttgctaagtt tacagaggtc tcagacgagc ttcttggtca aaacctttac attggttatg
    40621 ccttttcagt agtggaaccc tttatgatgt tggttggtta cggggcggtc ttcctctcta
    40681 tttggctggt cgcgggaatg gttcagtcgg atccgtctgt tgttggttcc atcgcttctt
    40741 ttgttaatta cctaagccag attatcttta ccattgttat ggttggattt ttgggaaatt
    40801 ctgtcagccg tgccatgatt tccatgcgtc gtattcgaga aattcttgac gcagagccag
    40861 ctatgacctt caaggatatc ccagatgaag agttggttgg aagtcttagc tttgaaaatg
    40921 tgacctttac ctatccaatg gacaaggaac cgatgctgaa agatgtgagc tttactattg
    40981 aacctggtca aatggttggt gtagttggag cgactggtgc aggaaagtca accttggctc
    41041 aattgattcc acgtctcttt gatccacagg acggggccat taaaatcggt ggcaaggata
    41101 ttcgagaagt gagtgaagga accctgcgta aaacagtttc catcgttctc caacgtgcca
    41161 ttctttttag tggaacgatt gcagataact tgagacaggg gaaggggaat gctactctat
    41221 ttgaaatgga gcgcgcagcc aatattgccc aggctagtga attcattcat cgtatggaga
    41281 aaacctttga aagtccagtt gaagaacggg gaaccaattt ctctggtgga caaaaacaaa
    41341 ggatgtcgat tgcgcgtggg attgtcagca atccacgtat tctgattttt gatgattcga
    41401 cctcagcctt ggatgccaaa tcagagcgct tggtgcaaga agctttgaat aaggacttga
    41461 aggggacgac aaccattatt attgctcaaa aaattagctc ggttgtccat gcagacaaga
    41521 tcttggttct aaatcaagga cgattgattg gtcaaggcac gcatgcagac ttggttgcca
    41581 acaatgccgt ttaccgtgaa atctatgaaa cacagaaatg aaagacaaac tataagaaaa
    41641 gtcaatagtt ttatctaaac tatttcttat ttcaatttga tgatttggcg atgattttag
    41701 agcacggcaa aaagctattg aaaaagtcca ttttttcaaa ggtaatcctg tgttaatttc
    41761 agaaattaca tcactttttg ttcgtcaaat ggcagctctt ttttaggata taaaacaggg
    41821 ttcggataag tttttttgca aggtggatga tggctacatt gtaatgtttt ccttgttcta
    41881 acttagtctt aagataggcc ttaaaagcag gtgaaaagcg agggcatgct ttggcagctt
    41941 gtatgagtac ctaccgcaga tgaggggaac cccgtttgac cattcttcct gctaaatcaa
    42001 tctgacctga ctgataaata gaagaatcca gtccagcgaa agcttgtaat tgagcaggat
    42061 tatcaaaggc atgaatattt cgaatctcgg ctaaaatgac cgcccctaaa cgattctcaa
    42121 tcccagtaac cgtcgtgatg accgagttga actcagccat caagtcattg acacatgttt
    42181 tcgccttgtc aatgagcctc ttgtaatgtt tgatgttttc attacaagag ataaaacgtt
    42241 tatgcgttat caaactcatg accaattgaa acaaaaagct gtggttagat cctttcggaa
    42301 attgtcaagc gattggagga aatgaactaa tccacagcgg cttattccaa gtataccact
    42361 tgggctttgg cagtagctaa ctgcgctaaa tataatataa ggaggagtaa aatgaagaca
    42421 gttcaatttt tttggcatta ttttaaggtc tacaagttct catttgtagt tgtcatcctg
    42481 atgattgttc tggcgacttt tgcccaagcc ctctttccag tcttttctgg acaagcggtg
    42541 acgcagctag ccaatttagt tcaagcttat caaaatggca atccagaact tgtatggcaa
    42601 agcctatcag gaatcatggt caatcttggc ctgctggttt tggttctatt tatctctagt
    42661 gtaatataca tgtgtctcat gacgcgcgtg attgcagaat cgaccaacga gatgcgcaaa
    42721 ggcctctttg gtaagcttgc tcagttgacg gtttctttct ttgaccgtcg acaagatggc
    42781 gatatcctgt ctcattttac cagtgatttg gataatatcc tccaagcctt taacgaaagc
    42841 ttgattcagg tcatgagcaa tattgtttta tacattggtc tgattcttgt catgttttcg
    42901 agaaatgtga cgctggctct catcaccatt gccagcaccc cattggcttt ccttatgctg
    42961 attttcatcg tgaaaatggc acgtaaatac accaacctcc agcagaaaga ggtagggaag
    43021 ctcaacgcct atatggatga gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt
    43081 caagaggata tgatggcagg atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt
    43141 aaaggaagaa tgttctcagg aattcttttc cctgtcatga atgggatgag cctgattaat
    43201 acagccatcg tcatctttgc tggttcggct gtacttttga atgataagtc tattgaaaca
    43261 agtacagccc taggtttgat tgttatgttt gcacaatttt cacagcagta ctaccagcct
    43321 attatccaag ttgcagcgag ttggggaagc cttcagttgg cctttactgg agctgaacga
    43381 attcaggaaa tgtttgatgc agaggaggaa atccgacctg aaaaggctcc aaccttcact
    43441 aagttgcaag aaagtgttga aatcagtcat atcgattttt catacttgcc tgataaacct
    43501 attttgaaag atgtcagcat ttctgcccct aaaggccaga tgacagcagt tgttgggcct
    43561 acaggttcag gaaaaacgac tattatgaac ctcatcaatc gcttttatga tgttgatgct
    43621 ggtggtattt attttgatgg taaagacatt cgtggctatg acttagatag tcttagaagc
    43681 aaggtgggaa ttgtattgca agattcggtc ttgtttagcg gaacgattcg agacaatatc
    43741 cgatttggtg tgccagatgc taatcaggaa atggttgagg tagcagcaaa agcaacccac
    43801 attcacgact atatcgaaag tttgcctgat aagtacgata ctcttattga tgatgaccag
    43861 agcatctttt caacagggca gaagcaattg atttcaatcg ctcgaaccct gatgacagat
    43921 ccagaagttc tcattctcga tgaagcaact tcaaacgtag atacggtgac ggaaagcaag
    43981 attcagcatg ccatggaggt ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc
    44041 ttgaaaacca ttctcaatgc agatcagatt attgtcctta aagatggaga agtcattgaa
    44101 cgtggtaacc accatgaact tttgaagcta ggtggctttt attcagaact ctatcacaat
    44161 caatttgttt tcgaataaga aagaagttgt cctatgtggg cagctttttc ttgtccataa
    44221 aaaatgttta tcacagcctt aaaaaaaaca tattagacga aagtcatttt gagtgatatg
    44281 ataggactat cgttagtatt cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt
    44341 gctgcaaatc tatgtcccgt agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt
    44401 agattcgcag agatcattcg tcaagtcggt ggtctccctt tagtcattcc tgttggtgat
    44461 gagtcagttg tacgtgatta tgtggaaatg attgacaaac tcattttgac aggaggccaa
    44521 aatgttcatc ctcagtttta tggagagaaa aagaccgtcg aaagcgatga ttacaatctg
    44581 gtccgtgacg aatttgaatt ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt
    44641 atggcaatct gtcgcggtgt ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa
    44701 gaaatcgaag gtcactggca aggactacct ttcgggacat ctcactctat tgagacagta
    44761 gaaggaagcg tggtggctaa gctatttggg aaagaaagtc aggtcaactc agtccatcgt
    44821 caaagcatta aagatttggc acctaatttc cgtgtaactg ctattgattc aagagaccaa
    44881 actattgaag cgattgagtc tatcgacgag caccgcatta tcggtttaca gtggcatcca
    44941 gagtttctgg ttaatgaaga agatggcaat ttagaattat ttgagtattt attgaatgaa
    45001 ctgtaacgat tggaacatct ggtcgttctt tcttttattt tttcaaaatt tttagaatgt
    45061 ggcattttac gcaaacgttt gaattctgat aaaaattgga gaaattcgac aaaaaaactt
    45121 gaaaaaaacg aaggtaagcg ttatgataga aaagaagaaa tattggagga agaacatgtc
    45181 acatattaaa tttgattact caaaagtttt agacaaattt gttgcaccac atgaagtgga
    45241 atacatgcaa tcacaagtaa cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg
    45301 tagcgacttc ttgggatggt tggaccttcc tgaaaaatac gaccgcgaag aatttgaccg
    45361 catcttgaaa gctgctgagc aaatcaagtc agacagcgat gttttggttg tgatcggtat
    45421 tggtggatct taccttggtg caaaagcagc aatcgacttc ttgaatcacc attttgctaa
    45481 cttgcaaaca aaagaagaac gcaaagctcc acaaatcctt tacgcaggaa actcaatctc
    45541 atctacttac cttgctgact tggtagagta tgttgcagac aaagacttct cagtaaacgt
    45601 aatttctaaa tcaggtacaa caactgaacc agcgattgct ttccgtgtct ttaaagaact
    45661 cttgattaag aaatacggtc aagaagaagc taacaaacgt atctatgcaa caactgaccg
    45721 ccaaaagggt gctgttaagg ttgaagcaga cgctaacggt tggggaacat ttgttgttcc
    45781 agatgatatc ggtggacgct tctcagtatt gacagccgtt ggtttgcttc caatcgcagc
    45841 atcaggagct gacataaaag ctcttatgga aggtgcgaat gcagctcgca aagactacac
    45901 ttcagacaaa atctctgaaa acgaagctta ccaatacgca gctgttcgta acatccttta
    45961 tcgtaaaggc tatgcaactg agatcttggt aaactatgag ccatcacttc aatacttctc
    46021 agaatggtgg aaacaattgg ctggtgaatc agaaggaaaa gaccaaaaag gtatctaccc
    46081 aacttcagcc aacttctcaa ctgacttgca ctcacttggt caatttatcc aagaaggaac
    46141 tcgtatcatg tttgaaacag ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc
    46201 tactttggaa gaagaccttg acggacttgg ttaccttcaa ggaaaagacg ttgactttgt
    46261 aaacaaaaaa gcaactgacg gtgttcttct tgcccacaca gatggtgatg taccaaacat
    46321 gtatgtgact cttccagagc aagacgcttt cactcttggt tacactatct acttcttcga
    46381 attggcaatt gccctttcag gttacttgaa tgctatcaac ccatttgacc aaccaggtgt
    46441 tgaagcttat aaacgtaaca tgtttgccct tcttggaaaa ccaggatttg aagaattgag
    46501 caaagaactt aacgcacgtc tataatagaa gaaaagagtg gtttgcccac tctttttact
    46561 ctctttatcc atagaaattg gactcagcca agacttgtga tataatatag aaagcaaaaa
    46621 ggcagacgcc tagataatag gagaaactat gtcaaaagat atccgcgtac gttacgcacc
    46681 aagtccaaca ggactactac acatcggaaa tgcccgtaca gcattgttta actacttgta
    46741 tgcgcgccat catggtggaa catttctcat ccgtatcgaa gatactgacc gtaaacgcca
    46801 tgtcgaggat ggtgaacgtt cacaacttga aaaccttcgc tggttaggca tggattggga
    46861 tgaaagtcca gaatcacatg agaattatcg ccagtctgag cgtttggact tgtatcaaaa
    46921 atacattgac caactattag ctgaaggaaa agcctataaa tcttacgtta cagaagaaga
    46981 gttggcagct gaacgtgaac gtcaagaagc tgctggtgaa acacctcgat atatcaacga
    47041 ataccttggt atgagtgaag aggaaaaagc ggcttatatc gcagaacgtg aagcagctgg
    47101 tatcatacca acagttcgtt tggctgtcaa tgagtcaggt atctacaagt ggcatgatat
    47161 ggtcaaaggt gatatcgaat ttgaaggtgg caatatcggc ggtgactggg ttatccaaaa
    47221 gaaagacggt tacccaactt acaactttgc cgttgttatc gatgaccacg atatgcaaat
    47281 ctctcatgtt atccgtggag atgaccatat tgctaataca ccaaaacagc ttatggtcta
    47341 tgaagctctt ggttgggaag ctccagagtt tggtcacatg accttgatta tcaactctga
    47401 gactggtaag aagttatcta aacgtgatac taatacactt caatttatcg aagattaccg
    47461 aaagaaaggt taccttccag aagcagtctt taactttatt gctcttcttg gttggaaccc
    47521 aggtggtgaa gatgagattt tctctcgtga agaactcatt aaactttttg atgaaaaccg
    47581 cctcagcaag tcaccagcag cctttgatca gaaaaaatta gactggatga gcaatgatta
    47641 tatcaagaat gcagaccttg aaaccatctt tgaaatggca aaaccattct tagaggaagc
    47701 aggccgtttg actgacaagg ctgaaaaatt agttgagctc tataaaccac aaatgaaatc
    47761 agtagatgag attatcccat tgacagatct tttcttctca gatttcccag aattgacaga
    47821 agcagagcgc gaagtcatga cgggtgaaac agttccaaca gttcttgaag cattcaaagc
    47881 aaaacttgaa gcgatgacag atgatgaatt tgtgacagaa aatatcttcc cacaaattaa
    47941 agcagtccaa aaagaaacag gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc
    48001 agtttcaggc gaaatgcatg ggccagaatt accagataca attttcttgc ttggacgtga
    48061 aaaatcaatt cagcatatcg aaaacattct aaaagaaatc tctaaataaa gaggatacaa
    48121 taatggacat ctgggaaaag atgtacgaag aagcacagaa actatacaat ccacatgaag
    48181 tatcagactt tgtttatgcc aatcatgttg tagctgcagt agaagcagga gatggacaaa
    48241 tatttacagg attctgtatg gagggaacct gtggtgtttt ccatctctgc gcagaacggg
    48301 cggccctctt caatatgtac caattttcag gacaaactaa ggttaagaaa gtattagcct
    48361 ttcgagataa accaccttat ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat
    48421 tccttttaga gcttaatgct gaaaataaag atgcagaatt catgatggac tataatataa
    48481 gaaaaacagt taaagtctca gaactaatcc cttattggtg gggagaagaa cgtgcttcta
    48541 agtttaatga gcgatagaag agtcagtata attctggctc tttttactat aaattgaaaa
    48601 aat
//
LOCUS       DAVHSL010000011        45480 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000011 DAVHSL010000000
VERSION     DAVHSL010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.011"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(1..282)
                     /locus_tag="VVR39_000616"
                     /pseudo
     CDS             complement(1..282)
                     /locus_tag="VVR39_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            347..643
                     /locus_tag="VVR39_000617"
     CDS             347..643
                     /locus_tag="VVR39_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU6030151.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDLVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            764..1708
                     /gene="manA"
                     /locus_tag="VVR39_000618"
     CDS             764..1708
                     /gene="manA"
                     /locus_tag="VVR39_000618"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU6030152.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1699..3204)
                     /locus_tag="VVR39_000619"
     CDS             complement(1699..3204)
                     /locus_tag="VVR39_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEU6030153.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIDFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSISLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKDLSNELRPFLFYG"
     gene            3421..3725
                     /locus_tag="VVR39_000620"
                     /pseudo
     CDS             3421..3725
                     /locus_tag="VVR39_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819367.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family DNA-binding protein"
     gene            complement(3754..4209)
                     /locus_tag="VVR39_000621"
     CDS             complement(3754..4209)
                     /locus_tag="VVR39_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6030154.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4229..5404)
                     /locus_tag="VVR39_000622"
     CDS             complement(4229..5404)
                     /locus_tag="VVR39_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6030155.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5463..6308)
                     /locus_tag="VVR39_000623"
     CDS             complement(5463..6308)
                     /locus_tag="VVR39_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6030156.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAENIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6433..6990
                     /locus_tag="VVR39_000624"
     CDS             6433..6990
                     /locus_tag="VVR39_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6030157.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7009..7476
                     /locus_tag="VVR39_000625"
     CDS             7009..7476
                     /locus_tag="VVR39_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU6030158.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7565..8194
                     /gene="upp"
                     /locus_tag="VVR39_000626"
     CDS             7565..8194
                     /gene="upp"
                     /locus_tag="VVR39_000626"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU6030159.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8368..8958
                     /gene="clpP"
                     /locus_tag="VVR39_000627"
     CDS             8368..8958
                     /gene="clpP"
                     /locus_tag="VVR39_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU6030160.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9037..9285
                     /locus_tag="VVR39_000628"
     CDS             9037..9285
                     /locus_tag="VVR39_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU6030161.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9386..10546
                     /locus_tag="VVR39_000629"
     CDS             9386..10546
                     /locus_tag="VVR39_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6030162.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10814..11683
                     /locus_tag="VVR39_000630"
     CDS             10814..11683
                     /locus_tag="VVR39_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6030163.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSNAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11687..12643
                     /locus_tag="VVR39_000631"
     CDS             11687..12643
                     /locus_tag="VVR39_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6030164.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12643..13407
                     /locus_tag="VVR39_000632"
     CDS             12643..13407
                     /locus_tag="VVR39_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030165.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13407..14117
                     /locus_tag="VVR39_000633"
     CDS             13407..14117
                     /locus_tag="VVR39_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030166.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14476..15132
                     /locus_tag="VVR39_000634"
     CDS             14476..15132
                     /locus_tag="VVR39_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6030167.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            15240..16335
                     /gene="prfB"
                     /locus_tag="VVR39_000635"
     CDS             join(15240..15311,15313..16335)
                     /gene="prfB"
                     /locus_tag="VVR39_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU6030168.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16353..17045
                     /gene="ftsE"
                     /locus_tag="VVR39_000636"
     CDS             16353..17045
                     /gene="ftsE"
                     /locus_tag="VVR39_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU6030169.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17038..17964
                     /locus_tag="VVR39_000637"
     CDS             17038..17964
                     /locus_tag="VVR39_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030170.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18250..20430
                     /locus_tag="VVR39_000638"
     CDS             18250..20430
                     /locus_tag="VVR39_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6030171.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20482..21297
                     /locus_tag="VVR39_000639"
     CDS             20482..21297
                     /locus_tag="VVR39_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6030172.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            21437..22780
                     /locus_tag="VVR39_000640"
     CDS             21437..22780
                     /locus_tag="VVR39_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6030173.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLSGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRADRKAKRQTF"
     gene            22995..24185
                     /locus_tag="VVR39_000641"
     CDS             22995..24185
                     /locus_tag="VVR39_000641"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU6030174.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24738..25673
                     /locus_tag="VVR39_000642"
     CDS             24738..25673
                     /locus_tag="VVR39_000642"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU6030175.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25707..26744
                     /locus_tag="VVR39_000643"
     CDS             25707..26744
                     /locus_tag="VVR39_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6030176.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            26917..27522
                     /locus_tag="VVR39_000644"
     CDS             26917..27522
                     /locus_tag="VVR39_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU6030177.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQNTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27678..28208
                     /locus_tag="VVR39_000645"
     CDS             27678..28208
                     /locus_tag="VVR39_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU6030178.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            28229..29314
                     /gene="rlmN"
                     /locus_tag="VVR39_000646"
     CDS             28229..29314
                     /gene="rlmN"
                     /locus_tag="VVR39_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU6030179.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29314..29796
                     /locus_tag="VVR39_000647"
     CDS             29314..29796
                     /locus_tag="VVR39_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6030180.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29798..31339
                     /locus_tag="VVR39_000648"
     CDS             29798..31339
                     /locus_tag="VVR39_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6030181.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31395..32198)
                     /locus_tag="VVR39_000649"
     CDS             complement(31395..32198)
                     /locus_tag="VVR39_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6030182.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32281..32493)
                     /locus_tag="VVR39_000650"
     CDS             complement(32281..32493)
                     /locus_tag="VVR39_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030183.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(32972..33181)
                     /locus_tag="VVR39_000651"
     CDS             complement(32972..33181)
                     /locus_tag="VVR39_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030184.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33351..33623
                     /gene="rpsP"
                     /locus_tag="VVR39_000652"
     CDS             33351..33623
                     /gene="rpsP"
                     /locus_tag="VVR39_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU6030185.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33643..33882
                     /locus_tag="VVR39_000653"
     CDS             33643..33882
                     /locus_tag="VVR39_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU6030186.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34459..35247
                     /locus_tag="VVR39_000654"
     CDS             34459..35247
                     /locus_tag="VVR39_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6030187.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35278..35796
                     /gene="rimM"
                     /locus_tag="VVR39_000655"
     CDS             35278..35796
                     /gene="rimM"
                     /locus_tag="VVR39_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU6030188.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35786..36505
                     /gene="trmD"
                     /locus_tag="VVR39_000656"
     CDS             35786..36505
                     /gene="trmD"
                     /locus_tag="VVR39_000656"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU6030189.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36517..36855
                     /locus_tag="VVR39_000657"
     CDS             36517..36855
                     /locus_tag="VVR39_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030190.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36886..37206)
                     /locus_tag="VVR39_000658"
     CDS             complement(36886..37206)
                     /locus_tag="VVR39_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030191.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37304..37519
                     /locus_tag="VVR39_000659"
     CDS             37304..37519
                     /locus_tag="VVR39_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU6030192.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37588..37668)
                     /locus_tag="VVR39_000660"
                     /pseudo
     CDS             complement(37588..37668)
                     /locus_tag="VVR39_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37724..38260)
                     /locus_tag="VVR39_000661"
     CDS             complement(37724..38260)
                     /locus_tag="VVR39_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU6030193.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(38457..39803)
                     /gene="gor"
                     /locus_tag="VVR39_000662"
     CDS             complement(38457..39803)
                     /gene="gor"
                     /locus_tag="VVR39_000662"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU6030194.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAQAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGVTKADFDATVAIHPTSSEEFVTMR"
     gene            40068..41267
                     /locus_tag="VVR39_000663"
     CDS             40068..41267
                     /locus_tag="VVR39_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU6030195.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     LTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            41251..41952
                     /locus_tag="VVR39_000664"
     CDS             41251..41952
                     /locus_tag="VVR39_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030196.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            41954..43213
                     /locus_tag="VVR39_000665"
     CDS             41954..43213
                     /locus_tag="VVR39_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030197.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            43337..45334
                     /gene="metG"
                     /locus_tag="VVR39_000666"
     CDS             43337..45334
                     /gene="metG"
                     /locus_tag="VVR39_000666"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU6030198.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDAVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        13892 a         8423 c         9911 g        13254 t
ORIGIN      
        1 tcaaatgacg ggcaagaaag gctttctctt cctcaactgt catatatgca tggttacgac
       61 caccacgtgt ttcttgaagg agagagtcga gtccgaactc ctcatatttt ttacattttg
      121 ctaaatcgtt gtttgattac agtctaaaag ctctataatc tctttataag atttgcccat
      181 cagacgaaat agaacgattt gaaggcgttt atgatattta gctgtacgag agtcttttaa
      241 aagtgttttg atggtttgga tttcttcttt agttgatttc atatcactat tatataatgc
      301 tttttgattt tagtttagta ttatcgtaga aaatggactc ggtgctatgg atacaccgga
      361 tgagaatggt tatgtagcag ataactatcg gattacttac ttagaggccc acatcaaggc
      421 catgcgagat gccatttacc aagacggggt tgacttgctt ggttatacga cttggggctg
      481 tatcgatctg gtttcagctg gcacagggga aatgaataag cgctatggct ttatctatgt
      541 agatcgagat aatgtaggaa acggagctct caaacgtagc aagaagaagt ccttctattg
      601 gtacaaggat gtcattgata gcaatggtgc aagcatcggg tagagcacat ttgtttacta
      661 tttttataaa atcttctccc tgctttataa gatgtaaaaa agagttcaat tcgaactctt
      721 tttttgctat aatgagggga gaaaaatcag acaggagatc gacatgtcag aaccattatt
      781 tttacaatca gttatgcaag aaaaaatctg gggtggagcc aagctacgtg atgagtttgg
      841 ctacgacatc ccaagtgaaa aaatcggaga atattgggcc atctcagccc atccaaatgg
      901 agtctctaaa gttgccaatg gtcgttacga gggaacagat cttgctactt tgtatgcgga
      961 acaccgtgaa ttatttggca atcgtccaga acctgtattt ccacttttga ccaagatcct
     1021 cgatgccaac gactggctca gtgtccaagt tcacccagac gatgcttatg gactcgagca
     1081 tgaaggcgaa ctcggaaaaa cagaatgctg gtacatcatc gctgcggatg aaggttcaga
     1141 gattatctac ggtcacaatg ccaagtcaaa agaagaactc cgccagcaaa tcgaggataa
     1201 gaactgggat gcgctgttga caaaagtgcc agttaaagca ggagatttct tctatgtacc
     1261 aagcggtacc atgcacgcta tcggggcggg tatcttgatt cttgaaaccc agcagtctag
     1321 cgataccact taccgtgtct atgactttga ccgtaaggat gacaagggca atttacgtga
     1381 acttcacctt gaaaaatcta tcgatgtctt gaacattggt gaacccgcaa atagccgtcc
     1441 agtgacaatc aaagcagatg atctacgttc cactctcctt gtatccaatg atttcttcgc
     1501 agtttacaaa tgggaaatta ctggaaaagt taactttgaa aagacagctg actacagctt
     1561 gttgagtgtc ttggctggtc aaggtcaact aactgttgac gggaaaaact atccaatcca
     1621 aaaagggaga cactttatcc taccaagtga tgttgaagct tggactctgg aagggcaaga
     1681 tttagaatta attgttagtc atccataaaa aagaaagggc ctgagttcat tactcaagtc
     1741 cttttgatta cataaattgg gcgatgaaga ccacgatgat gattggaatg acggaacgaa
     1801 gaaacgaaga aggaagagcc agacttggaa cagtccttgt ttccatgctc tttcatcgag
     1861 atggagttcc tccattgcaa gagccttttt aaagatatag cctgtaaaaa gtgaaaggta
     1921 gagagctcca aatggcatga ggagattgga aaccaagaag tccatagcgt caaagaaggt
     1981 cttaccaaaa atgtgaacat ccgccatgac accgtaagat agggctgaag gaatgccaaa
     2041 gacaaaggtc aaaattccta aaataacact ccatttggca cgtttgctgt tatcctggtt
     2101 ggtgatattg cccacattga tctccagcat cacgacagaa gaagtgacag tcgcaaagag
     2161 gaagaggacg tagaaaatgg ttccaaaagg catcttgtca aagagttgag gcaagacgat
     2221 aaagagcaag ctcggtcccc cttcagactg gatattgaag ggggatcgag cttggaaaat
     2281 ggctagacct gccatgatgg atatcgagat attcatggct acgatggaga ttcctgactg
     2341 gactagattg gttttcttgt ccaagtaaga agcataggtc aacatgactg taacccctag
     2401 tgagagggca aagaaagatt gtcccagagc atagaggaga ccagcgctag tcagttttga
     2461 aaagtctggt ttgaggaagt aaagaacccc ttccatggca tttggcaaac tgatagagcg
     2521 accgatgata acaacaaaga tgataaagag caggggcatc atgactttcg aagctctttc
     2581 aatccctttt tgaaccccac gtgatacaat aaagatattt aataagataa aggctgcttg
     2641 agctactagg gcaatggctg gatttgaaat gattgaagta aataactgag cataatcacc
     2701 cgttccacca agttggaaca atttcccaaa ctcaatacct agatagacta gaatccatcc
     2761 tccgataaca ctgtaaaaag ataagaggat aaagagggca aaggcgccaa tccaaccgat
     2821 aaagttgtac ttgttattct tgcccagttt tccaaaggtt ttgatagcgg aaacgccagc
     2881 actacggcca agggcaaact cagccagcag gagagggaaa tcgattaaaa tagtggaaat
     2941 gagaaagatt agtaaaaagc ctccaccgcc attagcagca gtcatgtagg gaaacttcca
     3001 aacggaacca agcccgatga ccgagccagc agatgctaga ataaagccaa gtttcgaccc
     3061 ccattgtgat ttttctgaca tagttaaact ctgatctcct ttttcaaaat aagaaaaagc
     3121 tacttgagtt gtcaaatagc cttctgtttg attgatagac ttgactatcc tattatgttt
     3181 tctaaggtct gtcaagaaaa ccattttcaa gttttcacac ctttctcaaa aacgcttgac
     3241 tctgacctaa ggggaggggt tatactatca ttgtaaggag gaaatcatgt accatataaa
     3301 agaagctgcg cagctttcag gtgtctctgt caagaccctg ccctgcatca ctatgacaag
     3361 ataggactct tggtcccctt aaagtcggaa aacggctatc gaacctatag tcaagaggat
     3421 ttggaacgcc ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata
     3481 gaagagctgt taaaggaaga aaggacagat ttattgcccc atttaactag gcagttggac
     3541 tatctaactc gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt
     3601 caagaacaaa aaaaggttac gtctacaacc cagagtttaa ggaaaacatt gacaagtttg
     3661 gttctgaaac agcccagtac acgtcagatg ccattgcggc ttacgttcag acaaatgcag
     3721 aataaatagg ctaggaattt cctagcctat tttttacttc aaatcataaa gccagtcgtc
     3781 accgtttttg tagtaaaaga attcactgag atcttcttct agaaacacac gaagcatatc
     3841 agacatatca tcggttgcaa gttttagatg agaaagattt tcaaagtcct cccaccaaac
     3901 tttcccttcg tctgaagact ggagttcacc agtaaagtgt tctgtcttgt aaaaaaggac
     3961 gacataacga taatccttgt cgtcatacca gtttttgata ccacagagtt ggggtttgga
     4021 aatgatcaga ccagtttctt ctttcacttc acgaatgaca gcatcgacaa aggattcgcc
     4081 acgttcaaca tgaccaccag gaaaagtaat gccaggccag tcgggactaa ctcggtcttg
     4141 gaccaggacc ttatctccgt ttttaatcat acacatgtta acaaattcga ctgcctctct
     4201 tctgttcatt cttcacaacc tttaatcttt aatcataatg cagacttccc gccacccagc
     4261 cggtacagag ggcagaagtg atgttaaaac cacccgtgtg ggcattgata tccataactt
     4321 cgcctgcaaa gtggaggcca ggtaccagct tactttcaag ggttttagga ttgatttcct
     4381 tgagactgac tccacccttg gtaacaaagg actttgcaag ggacattttt ccagttacag
     4441 gaattttaag ttctttaatg gactggacaa gttgttctcg ttccttttca gtcagttgtt
     4501 tgactttttc aggatatcct tgtacaaaaa attcggccaa gcgttctggt aacaaggttt
     4561 ttaaagcgtt tttcaaggat ttttcccgat tttcttctag aaatgtaacc aagtccttct
     4621 cagaaagttg aggcaaaaca tcgagtgaga gaacctcccc acctttgaca aagctagaca
     4681 tgcgtagggc agcaggacct gacaaaccaa agtgggtaaa gagtaaatca tgagtgatga
     4741 catgcttacc ataacttagg gtcacatcgt ccagagaaat cccttgtaag gctttatgtg
     4801 gaaaatctgt taataaagga ctttcagcag cctcaagatc ggtgatggta tgcttaaaat
     4861 ggcgagcaat ctcgtgacca aaaccagtcg aaccagtcga aggataagac ttaccacctg
     4921 ttgtgacaat gagtttctca caagtgaagg tttgatccgc tgacttaagg acaaactggt
     4981 catctacttt tttaacagaa acgatttcta tttgagtagc aacttgacca cctagttcgg
     5041 tgattttctt ttccaaagct tcgataatag tccgagactt gtcactggct ggaaagacgc
     5101 gtccgtggtc ttcgacctta agtttaacac cattttctgt aaaaaagttg atgatgtcat
     5161 gattatcgaa ctgggagaaa acactgtaaa gaaagcgtcc gtttccagga attccagcta
     5221 gcaggttgtc taagctacca ttgttggtca cattgcaacg tcccccacca gtcccagcta
     5281 atttttttcc aagtttccga tttttttcga tgaggagggt tttctgtcca taaaagctac
     5341 tggaaatcgt agccatcata ccagcaggtc ccccaccgat gacaatagta tcaaaatgtt
     5401 tcatagctct attgtaccac aaaaaaacaa gagatgatgg tcacatcttg tcaagaatgc
     5461 aattaatcaa tttcatagcc catcagcaaa ccgccctctt ctgcatagaa actgcagaga
     5521 ccagaggttg gtagaatttt aatatccgct tgtgggaagg tttcacggat tcgctctgag
     5581 agctgttgac aacatttttc gttattgcgt tgggccatga caatacggcc accagcatat
     5641 ccagctttta ctaactcatc ataggcagct tgaactgatt tctttgatcc ccttgctttt
     5701 tgtagcaatt cgagagttcc agtttcacta gcttttccga ccatacgaat gttgagaagg
     5761 ccaacgaccg taccgataag cttgctcaaa cggccgttct tcaccaagtt atcgactttg
     5821 gctaggacaa agagcaactt agttttttct tgataggcgg tgatagcttc aaccacttct
     5881 tcaaaagaca agccttggtc aatcaagtca ttcaattttt ctacgagtag gtcaacttca
     5941 ccaccagcag ataaactatc aatcacatga atcttagtgt caggatggtc ttccagataa
     6001 atattctttg ctagttgagc actattgtga ctgccagaaa gggtacctgt gatggttact
     6061 aggaaaatgt tttcggcacc ttcaaatgct cgcaaatagt catctgggct tggacaagct
     6121 gattttgaag cttctgcagt tgcatacatg gtttccatca tttggtcaat atcgagactg
     6181 gcgtcatcaa caaagacctg atcagctact tgaatggtta aggggacact tacaaaggtt
     6241 gtgttaatag ctggtgttgg cagttgacga taatcacaac cagagtcagc aataatcttc
     6301 caagtcatag aaattctcca tctttgtcag ttatacattg acaaaggttc tgtctttttt
     6361 tacaattata tcatgaaaac tcttgaaaca aaagcatcat ccgtctgttg tgacaagtag
     6421 aaagaaaatg ttatgtctga acgtagaatc tctgaaaagt ctcttgaaaa tctcagaaaa
     6481 tcaaaccaag aatccaattt attaaccaga gaagccattg aaacagccct cttgcaactc
     6541 ttggaaaaaa aggagctgac caagattagt atttctgaat tggtcaaacg tgcaggtgtt
     6601 tcgcgtgcgg ccttttatcg caattatgac tccaaagagg aaattttaga gagcgtcttt
     6661 aaacgaactg tccacaatat tatggaacag ctgcatcatt acgatttaaa gacagacctt
     6721 tatttggttt gggttcacct tttccgggag gccagaaagg aagctagagt gattcaattg
     6781 gccttggatt accatctgga aaaaatcttt gtccaagcca tgcaggaatt tctagaaaaa
     6841 taccatggga aatcaaaagg tgtcagctct tatcttcatt ccttctggag ctcagccatc
     6901 gtctctgtcc ttctaaaatg gatcaaggat ggcatgaagg taccagctga aaagattgca
     6961 gatttaggtt taccattttt taaaaaatag agaaaaagga gaaaagagat gactgaaaaa
     7021 agactggcct gggatgagta ttttgcagcc caagctctac taattgcgaa tcgttccact
     7081 tgtaaacgtg ctaaagtggg cgcgattctg gtaaaagata ataaggttat ttccactggt
     7141 tacaatggtt cggtgtcagg gactgagcat tgtattgatc acgaatgttt ggtcattgaa
     7201 ggccactgcg ttcgcaccct tcacgctgag gtcaatgcta tccttcaagg tgctgagcgt
     7261 ggtgttccca aaggctttac agcctatgta acccattttc cttgtctcaa ctgtacaaaa
     7321 caattgcttc aggtcggctg caagcgcgtg gtttatatca accagtaccg aatggacgac
     7381 tacgcccaat acctttatca agaaaaaggg acagaattga cccatttacc acttgagaca
     7441 gtacagacag ctcttaaaga ggctgatcta atgtaaaaat tatcaaaaat aaatggttta
     7501 gaaagatttt taaaccgttt tttggtataa taagaagaat aaattgaaag aaggaattcc
     7561 aaaaatggga aaaattgaag ttattaatca cccactgatt caacacaaat tgtcaatttt
     7621 gcgtcgtaca gatacttcta caaaagcttt tcgtgagcta gtagatgaga ttgcaatgtt
     7681 gatggggtat gaagtacttc gtgatcttcc actagaagat gtggaaatcg aaacaccaat
     7741 tacaaaaaca gttcaaaaac aattggcagg taagaaattg gccatcgtcc caatcttgcg
     7801 tgcaggtatc gggatggttg atggtctctt gagcttggtt ccagctgcta aagttggcca
     7861 catcggtatg taccgtgatg aagaaacact tcaaccagtt gaatacttgg tgaaattgcc
     7921 tgaggacatt gaccaacgtc aaatttttgt agtagaccca atgttggcaa caggtggctc
     7981 agcaatcttg gctgttgatt ctcttaaaaa acgtggcgca tcaaatatca aatttgtctg
     8041 ccttgtatct gctccagagg gtgtaaaagc ccttcaagaa gctcatccag atgtagaaat
     8101 ctttacagca gccttggatg aacgtttgaa tgaacacggt tatatcgttc caggtcttgg
     8161 agatgctgga gaccgcttgt tcggtacaaa ataagatcga aaagaagaat gacttggaaa
     8221 agtatttcta gtcacgaaag gaggttgggt ttttgtttct gtctaatgaa agcagagcaa
     8281 aaatttgacc ttttttgacc aagatattat aatagtctta tcttcagtca tttgaccaac
     8341 aaaattaaaa ctcaaaagga gaaatgaatg attcctgtag ttattgaaca aacaagccgt
     8401 ggagaacgtt cttacgatat ttactcacgt cttctcaaag accgcatcat tatgctgaca
     8461 ggtccggttg aagacaatat ggctaactct gttattgccc aattgctttt cttggatgcc
     8521 caagatagta cgaaagatat ttacctttat gtcaatacac caggtggttc tgtttcagct
     8581 ggtttggcaa tcgtagatac catgaacttt atcaaggcag atgtccaaac cattgttatg
     8641 ggaatggctg catctatggg gactgtcatc gcatcaagtg gagcaaaagg caaacgtttc
     8701 atgcttccaa atgctgaata catgattcac caaccaatgg gcggtacagg tggtggtacc
     8761 caacaaactg atatggctat cgctgcagaa cacttgctca aaactcgtaa taccttggaa
     8821 aaaatcttgg ctgaaaattc aggtcagtca atggaaaaag tccatgcaga tgcagaacgt
     8881 gataactgga tgagcgccca ggaaacactt gaatatggct ttattgatga aattatggcc
     8941 aacaattcat tgaactaatg atgatagaag gcaaactcga ctgggtttgc tttttttggt
     9001 ataataggga gagatttctt agaaagagga tttatcatgt ttgaaaaagt caatcgctct
     9061 ggcttgatta tctatcttta ctataatcgt gatgccaaaa aactgcagga ttatggagat
     9121 attacctatc attccaagaa acatcgttac ttacaactct atgttccaac tcaagaagtg
     9181 gagcaattgg tcggacgctt gagcaaggaa aaatttatta aaaaagttag ggtttgtcat
     9241 atccaagagt tggaaacacc ctttgtgggc aatctttatc gataggaaaa cgttatcatc
     9301 gaaaaagttc aaggaaaaca ttgacaattt tctgataatt cggtatattc ttaacagact
     9361 atttaagaaa taaggagaca aaaagatgaa gaaaaaattt gccctatcgt ttgtggcgct
     9421 tgcaagtgta gcacttcttg cagcctgtgg agaagtgaag tctggagcag tcaacactgc
     9481 tggtaactca gtagaggaaa agacaattaa aatcgggttt aactttgaag aatcaggttc
     9541 tttagctgca tacggaacag ctgaacaaaa aggtgcccaa ttggctgttg atgaaatcaa
     9601 tgccgcaggt ggtatcgatg gaaaacaaat cgaagtagtc gataaagata ataagtctga
     9661 aacagctgag gctgcttcag ttacaactaa ccttgtaacc caatctaaag tatcagcagt
     9721 cgtaggacct gcgacatctg gtgcgactgc agctgcggta gcgaacgcta caaaagcagg
     9781 tgttcccttg atctcaccaa gtgcgactca agatggattg actaaaggtc aagattacct
     9841 ctttattgga actttccaag atagcttcca aggaaaaatt atctcaaact atgtttctga
     9901 aaaattaaat gctaagaaag ttgttcttta cactgacaat gccagtgact atgctaaagg
     9961 gattgccaaa tctttccgcg agtcatacaa gggtgaaatc gttgcagatg aaactttcgt
    10021 agcaggtgac acagactttc aagcagccct tacaaaaatg aaagggaaag actttgatgc
    10081 tatcgttgtt cctggttact ataatgaggc tggtaagatt gtaaaccaag cgcgtggcat
    10141 gggaattgac aaaccaatcg ttggtggtga tggattcaac ggtgaggagt ttgtacaaca
    10201 agcaactgct gaaaaagcat caaacatcta ctttatctca ggcttctcaa ctactgtaga
    10261 agtttcagct aaagctaaag ccttccttga cgcttaccgt gctaagtaca atgaagagcc
    10321 ttcaacattt gcagccttgg cttatgattc agttcacctt gtagcaaacg cagcaaaagg
    10381 tgctaaaaat tcaggtgaaa tcaaggataa ccttgctaaa acaaaagatt ttgaaggtgt
    10441 aactggtcaa acaagcttcg atgcagacca caacacagtc aaaactgctt acatgatgac
    10501 catgaacaat ggtaaagttg aagcagcaga agttgtaaaa ccataataga aaaatgttga
    10561 aatagggaat gagcctttga ctcactccct gtttcgatat ttaatactct tcgaaaatct
    10621 cttcaaactg cgtcaacgtc gccttggatt atatatgtga ctgacttcgt cagtcttatc
    10681 tacaacctca aagcagtgct ttgagcaacc tgtggctagt ttcctagttt gctctttgat
    10741 tttcattgag tataagaacc tatcaaaaag tgagggaaac ccctcggaat tataaataga
    10801 aagagtgaat cttatgctcc aacaactcgt aaatggtttg attctaggta gtgtttacgc
    10861 gctgttagcc ctaggatata ccatggttta cggaattatc aagctcatca acttcgccca
    10921 tggtgatatt tatatgatgg gagcctttat cggttatttc ttgatcaatt ctttccaaat
    10981 gaatttcttt gtagcgctta ttgtagctat gctagcgaca gctattcttg gtgtcgtgat
    11041 tgagtttctt gcttaccgac ctttgcgcca ctctactcgt attgctgttt tgattacggc
    11101 tattggggtt tctttcctat tggagtatgg aatggtctat ctggttggtg ccaatacccg
    11161 tgccttccct caagcgattc aaacagttcg atatgatttg ggaccaatta gcttaacaaa
    11221 tgtgcagtta atgattttgg ccatttcctt gattttgatg attttgttac aagtcattgt
    11281 ccaaaagact aagatgggga aagccatgcg tgcagtatca gtagatagca acgcggcgca
    11341 attgatgggg atcaatgtaa accgtacgat tagctttacc ttcgctttgg gttctgctct
    11401 tgcgggtgcg gctggtgttc tgattgctct ttattataac tctcttgagc ctttgatggg
    11461 ggttactcca ggtcttaaat ctttcgttgc cgcagtactt ggtggtatcg gaattattcc
    11521 tggtgcggct cttggtggct ttgtgattgg tctattggaa acctttgcga cagcctttgg
    11581 gatgtcagat ttccgtgatg ccattgttta tggaatcttg ttgttgatct tgattgtccg
    11641 cccagctggt atccttggta agaatgtgaa agagaaggtg taaacgatga aggaaaattt
    11701 aaaagttaat attctatggt tactcctttt gttagctggc tatagcttga ttagtgtact
    11761 ggtttcagtc ggagtactta atctattcta tgtacagatt ttacaacaaa ttggaattaa
    11821 tattattttg gctgttggtc tcaacttaat cgttggtttt tcaggacaat tttcacttgg
    11881 tcatgctggt ttcatggcga ttggtgccta tgcagcagct attattggtt ctaaatcacc
    11941 aacctacggt gccttctttg gagctatgct tgtaggggct ttgctttcag gagcagttgc
    12001 cttacttgtc ggcattccaa ccttgcgctt gaagggggac tatcttgcgg tagcaactct
    12061 gggtgtttct gaaattatcc gtatctttat catcaatggt ggaagtctta caaatggtgc
    12121 ggcaggtatc ttagggattc ctaactttac aacttggcaa atggtttact tctttgtcgt
    12181 gattacaacc attgcaacct tgaacttctt gcgtagccca attggtcgtt caaccctctc
    12241 tgttcgtgaa gatgaaatcg ctgctgagtc agttggggtt aatacgacta aaattaaaat
    12301 catcgctttt gtctttggtg ccattactgc aagtattgct gggtcacttc aggcaggatt
    12361 tatcgggtct gttgtaccga aagattacac cttcatcaac tcaatcaacg ttttgattat
    12421 tgttgtattt ggtggactcg gttccattac aggtgcgatt gtttcggcta ttgttctggg
    12481 aattttgaat atgcttctcc aagatgttgc tagtgtgcgt atgattattt acgctttggc
    12541 cttggtattg gtaatgattt tcagaccagg tggactcctt ggaacgtggg aactgagcct
    12601 atcacgtttc tttaaaaaat ctaagaagga ggaacaaaac taatggcatt acttgaagta
    12661 aaacagttaa ccaaacattt tggtggtcta acagctgttg gagatgtgac tcttgaattg
    12721 aacgaagggg aactggttgg attaatcggt ccaaacggag ctgggaaaac cacccttttc
    12781 aaccttttga ccggtgttta tgaaccaagc gagggaacag taaccctaga tggtcacctt
    12841 ttgaatggga aatcacctta taagattgcc tctttgggac ttggacgtac tttccaaaat
    12901 atccgtctct ttaaagattt aacagtttta gataatgttt tgattgcttt tggaaaccat
    12961 cacaaacagc atgtttttac tagtttctta cgcttaccag ctttttacaa gagtgaaaaa
    13021 gaattaaagg ctaaagcttt ggaattgttg aaaatctttg atttagatgg tgatgcagag
    13081 actcttgcta aaaatctttc ctacggacaa caacgtcgtt tggaaattgt tcgtgccctt
    13141 gctacggaac ctaaaattct cttcttagat gaaccagcag caggtatgaa cccacaggaa
    13201 acagccgaat tgactgagtt aattcgtcgt atcaaagatg aatttaagat tacaatcatg
    13261 ttgattgaac acgatatgaa tctggtcatg gaagtaacag aacgtatcta cgtacttgaa
    13321 tatggccgtt taattgctca aggaactcca gacgaaatta agaccaataa acgcgttatc
    13381 gaagcttatc taggaggtga agcctaatgt ctatgttaaa agttgaaaat ctttctgtgc
    13441 attacggtat gatccaagca gtccgtgatg taagctttga agttaatgaa ggagaagttg
    13501 tttcccttat cggtgccaac ggtgcaggta agacaactat tcttcgcacc ttgtcaggtt
    13561 tggttcgacc aagttcagga aagattgaat ttttaggtca agaaatccaa aaaataccag
    13621 ctcagaaaat cgtggcaggt ggtctttcac aagttccaga aggacgccac gtctttcctg
    13681 gcttgactgt tatggaaaat cttgaaatgg gagctttctt aaagaaaaat cgtgaagaaa
    13741 atcaagctaa cttgaagaag gttttctcac gctttcctcg tcttgaagaa cgtaagaacc
    13801 aagatgcagc tactctttca ggaggggaac aacaaatgct tgccatggga cgcgctctta
    13861 tgtcaacacc aaaacttctt cttttagatg aaccatcaat gggacttgcc ccaatcttca
    13921 tccaagagat ttttgatatc attcaagata ttcagaagca aggaacaacc gtcctcttga
    13981 ttgaacaaaa tgccaataaa gcacttgcaa tctctgaccg aggatatgta ttggaaacag
    14041 gaaaaatcgt cctatcagga acaggaaaag aactcgcttc atcagaagaa gtcagaaaag
    14101 catatctagg tggctaaaac aatccagtgg attgttttag tcggcagatg aagattacga
    14161 agtaatcatc aatatagtcc gggggccctt tttagtcggt ggatgaagat tgcgaagcaa
    14221 tcatcaaatc cagaggattg ttttagccgg tagattgaga ttgcaaacaa atctgcatct
    14281 acattgaaag cttaatttct aataattgaa aaaatcgaat gaaaagtttc ttaccttcat
    14341 tcacagagct cgattttaga gctctttttg ctagcttatt catacttttc taaattttga
    14401 aaaagaaatg taagcgtttg atagatttgc aaaaagattg tataataggg ataagaatag
    14461 aaaaggagaa gtctcatggc agttaaagat tttatgaccc gcaaggtagt ttatattagt
    14521 ccagatacaa cagtatctca tgcagcagat ttgatgagag agcaagaatt gcatcgcttg
    14581 cctgttatcg aaaatgatca attggttggt ttggtgactg agggaaccat tgcacaagca
    14641 agtccatcta aagcaacaag tctttctatc tatgagatga attatcttct gaataagaca
    14701 aaagtaaaag atgtcatgat tcgcgatgtt gtcactgtct caggctatgc tagtctagaa
    14761 gatgcaactt atctgatgtt gaaaaataag attggtattc tccctgtcgt agataaccat
    14821 caagtatacg gagttattac tgaccgtgac gttttccaag cctttcttga aattgcaggt
    14881 tatggcgaag aagggattcg tgtacgcttt gttacagaag atgaagttgg tgttcttgga
    14941 aaaattgttt ctttgattgt agaagaaaat ttgaatatct cccatacagt caatattccg
    15001 cgtaaggatg gtaaggtgat tatcgaagtg caaatcgatg aatcaattga tttaccagcc
    15061 ttgagagaaa aatttgaagc aaatggtatt caagtggaag aaatcgctcg cacttcagca
    15121 aaagtcttgt aagaagggaa gtccaaaggc ttcttttttc atgaaaaggg gattagagca
    15181 aaagatggaa agaaatgata aaatatgcta taatgaaata atgtaaaaaa ggagtattta
    15241 tggacatttc agtaattcgt cagaaaattg acgcaaatcg tgaaaaatta gcttctttca
    15301 gggggtctct ttgacctcga agggctagag gaagagattg ccatcttgga aaacaagatg
    15361 acagaacctg atttttggaa cgataatatt gcggcccaaa aaacgtcgca agaattgaat
    15421 gaattaaaaa acacttacaa taccttccat aagatggaag agttgcagga tgaagtcgaa
    15481 attttattgg attttttggc tgaagacgag tcagtgcatg atgaactggt agcgcaatta
    15541 gccgaacttg ataagataat gaccagctac gagatgactc tactcttgtc agaaccttat
    15601 gaccacaaca atgccatctt ggaaatccat ccaggttctg gtggtactga ggcgcaggac
    15661 tggggtgata tgttgcttcg tatgtatact cgttatggta atgctaaagg ctttaaagtg
    15721 gaagtgttgg attaccaagc aggtgatgag gctggtatta agtcggtaac tttatcattt
    15781 gaagggccta atgcctatgg tctcctcaag tcagaaatgg gtgttcaccg cttagtgcga
    15841 atctcaccat ttgactctgc caaacgtcgc catacctctt tcacatctgt agaagtgatg
    15901 ccagaattgg atgatactat tgaagtggaa atccgtgaag atgatatcaa gatggatacc
    15961 ttccgttcag gtggtgccgg tggacaaaac gtcaataagg tttcaacagg tgtacgttta
    16021 acccacattc caactggaat tgttgtccaa tcaacagtgg atcgtaccca gtatggaaat
    16081 agagatcgtg ccatgaagat gttgcaggct aagctctatc aaatggagca agataagaag
    16141 gctgcggagg tagattctct caaaggtgag aaaaaggaga tcacttgggg aagccaaatc
    16201 cgttcttatg tcttcacgcc ttatactatg gtaaaagatc accgaactag ctttgaggtt
    16261 gctcaggtag ataaggttat ggatggggac ctagatggtt ttatcgatgc ttatctcaag
    16321 tggcgaatta gctaagatag aaaggaactc acatgtcaat tattgaaatg agagatgtcg
    16381 ttaaaaaata cgacaacgga acgactgctc tacgcggtgt ttcggtcagc gttcaaccgg
    16441 gggaatttgc ttacatcgta ggaccttcag gagcagggaa gtcaactttt attcgttctc
    16501 tgtatcgtga agtaaaaatc gataaaggaa gtctatcagt tgctggtttt aatctggtta
    16561 agatcaaaaa gaaagatgtc ccgcttctac gtcgtagtgt tggggttgtc ttccaagatt
    16621 ataaattgtt accaaagaaa actgtctatg aaaatattgc ttacgctatg gaagtaatcg
    16681 gggaaaatcg ccgtaatatc aaaagacgag tgatggaagt tttggacttg gttggattga
    16741 agcataaggt tcgttctttc ccaaatgaac tctcaggtgg ggagcaacag cgaattgcga
    16801 ttgcgcgtgc aattgtaaat aatcccaaag tattgatagc tgatgagcca acaggaaatc
    16861 tggatccgga taattcatgg gaaattatga atctcttgga acggattaac ctacaaggaa
    16921 caactatttt gatggcgact cataatagcc agattgtaaa taccttgcgc caccgtgtca
    16981 ttgccattga aaatggccgt gtcgttcgtg acgaatcaaa aggagagtat ggatacgatg
    17041 attagtagat tttttcgcca tttatttgaa gccttaaaaa gtttgaaacg aaatggttgg
    17101 atgacagtag ctgctgtcag ttcagtcatg attactttga ccttggtggc aatatttgca
    17161 tctgttattt tcaatacagc gaaactagct acagatattg aaaataatgt ccgtgtagta
    17221 gtttatatcc gaaaggatgt ggaagataat agtcagacaa ttgaaaaaga aggtcaaact
    17281 gttacaaata atgactacca caaggtatat gattctttga agaacatgtc tacggttaaa
    17341 agtgttacct tttcaagtaa agaagaacaa tatgaaaaat taaccgagat aatgggagat
    17401 aactggaaaa tctttgaagg agatgccaat cctctctatg atgcctatat tgtagaggca
    17461 aacactccaa atgatgtaaa aactatagcc gaagatgcta aaaaaattga aggtgtctct
    17521 gaggttcaag atggcggtgc caatacagaa agactcttca agttagcttc atttatccgt
    17581 gtttggggac tagggattgc tgctttgtta atttttatcg cagttttttt gatttcaaat
    17641 accattcgta ttaccattat ttcccgcagt cgcgaaattc aaatcatgcg cttggtcgga
    17701 gctaaaaaca gttatatccg tggaccgttc ttgttagaag gagcctttat cggtttattg
    17761 ggagctatcg caccatctgt tttggtcttt attgtttatc aaattgttta ccaatctgtc
    17821 aacaaatcgt tggtagggca aaatctatcc atgattagtc cagatttatt tagtccgttg
    17881 atgattgccc tactatttgt gattggggtt ttcattggtt cattgggatc aggaatatcc
    17941 atgcgccgat tcttgaagat ttaggtaaaa tagctgcttt tatgaggaga ttgcaaaatc
    18001 tccttttttg ctacaagagt ttttgaaaag agatgcgcag aagaaaagag cttccaaaga
    18061 agtcccccag agaagacttc ttgatggcta atttgaactt gaaatttggc gcactagaaa
    18121 ttttttagaa aaaagtgtaa tttttttata aaagccttta caaaaaaaat taaagtggta
    18181 taattaaatc atagaaagtg caaacgtttt cgtaaaacgt ttgcctaaat aaaaataaag
    18241 gagatttgaa tgatgaaaga tacattcaaa aatgtcttgt ctttcgaatt ttggcaaaaa
    18301 ttcggtaagg ctttgatggt agttatcgcg gttatgccgg ctgctggttt gatgatttca
    18361 atcggtaagt ctatcgtgat gattaaccca acctttgcac cacttgtcat cacaggtgga
    18421 attcttgagc aaatcggttg gggggttatc ggtaaccttc acattttgtt tgccctagcc
    18481 attggaggaa gctgggctaa agaacgtgct ggtggtgctt tcgccgctgg tcttgccttc
    18541 atcttgatta accgtatcac tggtacaatc tttggtgtat caggcgatat gttgaaaaat
    18601 ccagatgcta tggtaactac tttctttggt ggttcaatca aagttgctga ttactttatc
    18661 agtgttcttg aagctccagc cttgaacatg ggggtattcg tagggattat ctcaggtttt
    18721 gtaggggcaa ctgcttacaa caaatactac aacttccgta aacttcctga tgcactttca
    18781 ttcttcaacg ggaaacgttt cgtaccattt gtagttattc ttcgttcagc aatcgctgca
    18841 attctacttg ctgctttctg gccagtagtt caaacaggta tcaataattt cggtatctgg
    18901 attgccaact cacaagaaac tgctccaatt cttgcaccat tcttgtatgg tactttggaa
    18961 cgtttgctct tgccatttgg tcttcaccac atgttgacta tcccaatgaa ctacacagct
    19021 cttggtggta cttatgacat tttaactggt gcagctaaag gtactcaagt attcggtcaa
    19081 gacccactat ggcttgcatg ggtaacagac cttgtaaacc ttaaaggtac tgatgctagt
    19141 caatatcaac acttgttaga tacagtacat ccagctcgtt tcaaagttgg acaaatgatc
    19201 ggttcattcg gtatcttgat gggtgtgatt gttgctatct accgtaatgt tgatgctgac
    19261 aagaaacata aatacaaagg tatgatgatt gcaacagctc ttgcaacatt cttgacaggg
    19321 gttactgaac caatcgaata catgttcatg ttcatcgcaa cacctatgta tcttgtttac
    19381 tcacttgttc aaggtgctgc cttcgctatg gctgacgtcg taaacctacg tatgcactca
    19441 ttcggttcaa tcgagttctt gactcgtaca cctattgcaa tcagtgctgg tattggtatg
    19501 gatatcgtta acttcgtttg ggtaactgtt ctctttgctg taatcatgta ctttatcgca
    19561 aacttcatga ttcaaaaatt caactacgca actccagggc gcaacggaaa ctacgaaact
    19621 gctgaaggtt cagaagaaac cagcagcgaa gtgaaagttg cagcaggctc tcaagctgta
    19681 aacattatca accttcttgg tggacgtgta aacatcgttg atgttgatgc atgtatgact
    19741 cgtcttcgtg taactgttaa agatgcagat aaagtaggaa atgcagagca atggaaagca
    19801 gaaggagcta tgggtcttgt gatgaaagga caaggggttc aagctatcta cggtccaaaa
    19861 gctgacattt tgaaatctga tatccaagat atccttgatt caggtgaaat cattcctgaa
    19921 actcttccaa gccaaatgac tgaagcacaa caaaacactg ttcacttcaa agatcttact
    19981 gaggaagttt actcagtagc agacggtcaa gttgttgctt tggaacaagt aaaggatcca
    20041 gtatttgctc aaaaaatgat gggtgatgga tttgcagtag aacctgcaaa tggaaacatt
    20101 gtatctccag tttcaggtac tgtgtcaagc atcttcccaa caaaacatgc ttttggtatt
    20161 gtgacggaag caggtcttga agtattggtt cacattggtt tggacacagt aagtcttgaa
    20221 ggtaaaccat ttacagttca tgttgctgaa ggacaaaaag ttgcagcagg agatctcctt
    20281 gtcacagctg acttggatgc tatccgtgca gcaggacgtg aaacttcaac agtagttgtc
    20341 ttcacaaatg gtgatgcaat taaatcagtt aagttagaaa aaacaggttc tcttgcagct
    20401 aaaacagcag ttgctaaagt agaattgtaa tatacttgag gttggaagct gtattccaac
    20461 ctcttatttt gggagaaaag aatgaaattt ttaacactca atactcacag ttggatggag
    20521 aaagaagcag aggaaaaatt ccagattttg cttgaagata ttcttgaaaa ggactatgat
    20581 ttgatttgtt ttcaagaaat caatcaggag atgacctcgt cagaggtgga ggttaatgac
    20641 ctttatcaag ctttgccagc agctgagcct attcaccaag accattatgt tagactcttg
    20701 gttgaaaagt tgtctgagca agggaaaaat tactactgga cctgggccta taaccatatc
    20761 ggctataacc gctaccacga aggtgtggct atcttgtcta aaacacctat tgaagccaga
    20821 gaaattttgg tttcagatgt ggatgatcca acagactatc atactcgccg tgttgcccta
    20881 gctgaaactg tagtcgatgg caaggagcta gcagttgcca gtgttcatct ctcttggtgg
    20941 gataaaggtt tccaagaaga atgggcacga tttgaggctg tcttgaaaaa attgaacaag
    21001 ccacttttac tagctggaga tttcaacaat ccggctggac aggaaggtta ccaagctatt
    21061 ttagctagtc cattaggctt acaagacgca tttgaagttg ctcaagagaa aagtggtagc
    21121 tatactgttc cgcctgaaat tgatggctgg aaagggaaca ctgaacccct tcgaatcgat
    21181 tatgtcttta ctaccaaaga gttagcggtg gaaaatttac atgtcgtatt tgatggtaac
    21241 aagagtccac aagtgagtga tcactatggc ttgaatgcta tgttaaactg gaaataataa
    21301 ctgaaaagag gttggaacta taaaattcca gccttttctt actagagaag ctactggaaa
    21361 tagcctaaat aagtgagact actgtaatgg aataaaatat ggtataattg ataagataga
    21421 tagaatcgag gatgttatgt catttacgaa atttcaattt aaaaactata ttagagaagc
    21481 cttggaggag ttaaaattta caactccaac agaggtgcaa gacaagttga ttcctattgt
    21541 tttggcaggt cgtgacctag taggagaatc aaaaacaggt tcaggtaaga ctcatacttt
    21601 cttgttaccg attttccagc aattagatga agctagcgat agtgtacaag cagtgattac
    21661 tgcaccgagt cgtgagttgg ctactcaaat ttaccaagta gcgcgtcaga tttcagctca
    21721 ctcagatgtc gaagttcgtg tggttaatta tgtgggtggt acggataagg ctcgccagat
    21781 tgagaaattg gcaagcaatc agcctcatat tgttattgga acaccaggcc gtatctacga
    21841 cttggttaaa tctggtgatt tagctattca taaagccaag acatttgttg ttgatgaagc
    21901 agatatgacc ttggatatgg gattcttgga aactgttgat aagattgctg gcagtcttcc
    21961 aaaagacttg caattcatgg tcttctcagc gactatccca caaaaactgc aaccattctt
    22021 gaaaaaatac ttatccaatc ctgttatgga gaaaattaag accaaaacgg ttatttctga
    22081 caccattgat aattggttga tttcgaccaa gggacatgat aagaatgctc aaatttacca
    22141 gttgactcag ttgatgcagc cgtatttggc aatgattttt gttaacacta aaacgcgtgc
    22201 tgatgaattg cattcatatc tgactgctca aggcttgaag gttgcaaaaa tccatggaga
    22261 tattgcccct cgtgaacgca agcgaatcat gaatcaggtg caaaatctgg attttgagta
    22321 tattgtcgca acagatttgg cagcgcgtgg gattgacatt gaaggtgtca gccatgtcat
    22381 caatgatgcc attccgcaag acttatcttt ttttgttcat cgtgttggtc gtactggacg
    22441 aaatggccta tcaggtacag ctattaccct ttatcagcca agtgatgact cggatatccg
    22501 tgagttggag aaattgggaa tcaagtttag tcctaagatg gtcaaagacg gggaatttca
    22561 agatacctat gaccgtgatc gtcgtgccaa ccgtgagaaa aaacaagata aacttgatat
    22621 cgaaatgatt ggtttggtta aaaagaaaaa gaaaaaagtc aaaccgggtt ataagaagaa
    22681 aattcaatgg gcggttgatg aaaagcgccg taaaaccaag cgtgctgaaa atcgcgctcg
    22741 cggtcgtgca gatcgtaaag ctaaacgcca aacattttaa tagaaattgt tggagtactg
    22801 agctccaact tttttattta tgagaacgaa ctatctaaac cgaaacacta cattaaagac
    22861 tgcaaattgc gattaaaaat ggtataatga taaagttata tagtcccgat aagatggtag
    22921 gtatttatta cgaagagttt tcctatcagt actttgtaac tctataacaa tattttttaa
    22981 ggggggacat ttttatgtca gaacgtaaat tattcacgtc tgaatctgta tctgaggggc
    23041 atccggataa gattgcagac caaatttcag atgcgatttt ggatgctatt ttagcaaagg
    23101 atccagaggc gcatgttgct gctgaaacag ctgtatatac tggttctgtc cacgtttttg
    23161 gtgaaatttc tacaaatgcc tatgtggata ttaaccgtgt ggttcgtgat accattgcag
    23221 agattggtta taccaataca gaatatggat tttctgctga gacggtggga gtacacccat
    23281 ctttggtgga acaatctcct gacatcgctc aaggtgttaa cgaagccttg gaggttcgtg
    23341 gaaatgctga tcaagatcca ctggacttga ttggagcagg tgaccaaggg ctcatgtttg
    23401 gatttgcagt agatgaaaca gaagagctta tgccattgcc aattgcactc agtcataaat
    23461 tggttcgtcg tctggcagaa cttcgtaagt ctggagaaat tagctatctc cgtccagatg
    23521 caaaatcaca agttacagtt gagtacgatg aaaatgaccg tccggtacgt gtagatacag
    23581 tcgttatttc tactcagcat gatccagagg ccactaatga acaaatccat caagatgtga
    23641 ttgacaaggt catcaaagaa gttattccat cttcttatct tgatgataag acaaaattct
    23701 ttatcaatcc gacaggtcgt tttgtaatcg gtggtcctca aggggactca ggtttgactg
    23761 gtcgtaagat tattgtagat acttatggtg gctactctcg tcatggtggt ggtgccttct
    23821 ctggtaaaga tgcgactaag gtggatcgtt cagcctctta tgcggctcgc tatattgcca
    23881 agaatatcgt tgcagcaggc cttgctaaga aggcagaagt gcagttggcc tatgctatcg
    23941 gtgttgcgca acctgtttct gttcgtatcg atactttcgg tacaggaaca gtagctgaaa
    24001 gtcaacttga aaaagcggct cgtcaaatct ttgaccttcg ccctgcaggg attatccaaa
    24061 tgctggacct caagcgtcca atttaccgtc aaacatcggc ttacggtcac atgggacgta
    24121 cagatattga tcttccatgg gaacgtttgg ataaggtaga tgctttgaaa gaagcagtaa
    24181 aataagattt taagagggga acgtcctctc ttttttatag tttttaacta tactgggata
    24241 ctgttctgaa aatccatttt gcgaaagtag agatttacat gtatagtaga ttgaaactag
    24301 aatagtacac ctcaacttct aaaacattgt tagcaatcaa tttgactgtc ctgatcgatt
    24361 tctcctgttc ttgtttcatt ttactatatt tctttaaaaa tgataaaggt taagatttct
    24421 cctcgtaata gataatcttg aggatatttc aatccaaagt tttattcgtt atcacttgac
    24481 tattgcaagg ttttctagag caacagagtc atggaatgga ctcatggttg agatttctcc
    24541 ttgttgcttg gacttcattc aaaagtctgt tacccaagcc ttgttcaaac ttctaataca
    24601 ctagctgttt ccatagcatg acttctgtac tagactttct tttccaaata aatagataga
    24661 accacagaat ctagtaaacc tagaattaaa attatggtat aatattagca ataaaagaaa
    24721 tctggaggat tagaatcatg gtatcaacga aaacacaaat tgctggtttt gagtttgaca
    24781 attgcttgat gaatgcagca ggtgtggctt gtatgacgat agaggagtta gaagaggtca
    24841 aaaactcagc ggcaggaacc tttgttacta agacagcgac cttggacttc cgtcagggga
    24901 atcctgagcc acgctaccaa gatgttccac ttggttccat caactctatg ggcttgccaa
    24961 ataatggctt agactattat ttggattatc ttttagattt gcaggaaaaa gagtcgaacc
    25021 gaactttctt cttatctctg gtcggcatgt ctccagagga aacccatact attttgaaaa
    25081 aagtccaaga gagtgatttt cgtggtctga ctgagctaaa tctttcctgt ccaaatgttc
    25141 caggtaaacc tcagattgcc tatgattttg agacaacaga ccggattttg gcagaagtgt
    25201 ttgcttactt caccaaacct cttggaatta aattgccacc ttattttgat attgttcact
    25261 ttgatcaagc ggcagctatt ttcaacaaat atccgctcaa gtttgtcaac tgcgttaact
    25321 ctatcggaaa cggcctctat atagaagacg aatctgtcgt tattcggcct aagaatggtt
    25381 ttggtggaat tggtggagaa tacatcaaac cgactgcttt agccaatgtt cacgcctttt
    25441 atcaacgttt aaatcctcaa atccaaatta tcggaacagg tggcgttctg actggtcgag
    25501 atgcctttga acacatcctc tgtggagcaa gtatggtgca ggtgggaacg acccttcaca
    25561 aagaaggcgt cagtgctttt gaccgcatta ccaatgaact gaaagcaatc atggtggaaa
    25621 aaggctacga gagcttagaa gatttccgtg ggaaattgcg ctatattgac taaattaaat
    25681 cgaaaaatct gaagaaagga gagacgatgc tagccattga agaaagtcag aagttgactt
    25741 tatcaaattt accgagcctg agcctattta cagggacaga tcagggtcag tttgaagtga
    25801 tgaagagtca agtgttgaaa cagattgggt atgattctgc tgacctcaac tttgcctact
    25861 ttgatatgaa agaagtagtt tacaaggatg tggaactgga gttggtcagc cttcctttct
    25921 ttgcggatga gaaaatcgtg atattagatt attttatgga tatcacgact gctaagaaac
    25981 gctttttgac agatgatgag cttaagtcat ttgaggaata ccttgacaat ccttctccaa
    26041 caaccaagtt gataatcttt gcagaaggaa agctggatag caaaagacgg ttagtcaaat
    26101 tacttaagcg tgatgccaag gccttcgatg cagtagaagt aaaagaacaa gaattgcgcc
    26161 agtacttcca aaagtggagt cagaaacaag gtctgcagtt taccaatcat tcttttgaaa
    26221 atctcctcat caagtcgggg tttcaattta gcgaaatcca gaaaaatctt ctctttttac
    26281 agtcctataa ggcggattct gttatcgagg aagaggatat tgttaacgca attcccaaga
    26341 ccttgcagga caatattttt gatttaactc agtttattct gactaaaaag atggatcagg
    26401 cgcgcgattt ggtgagagac ttgaccttgc aaggggaaga tgaaatcaaa ctgattgcag
    26461 tcatgctggg acaatttcgg acttttactc aggtgaagat tttggcggag tctggccaaa
    26521 cagaatcgca gattgcaagt agtttaggta gttatctggg acgtaaccca aatccttatc
    26581 aaatcaagtt tgcattaaga gattcgagag gactttcttt gagctttctg aagcaagcta
    26641 tttcctattt gattgagaca gactatcaga ttaagacagg tctttatgaa aaaggtttcc
    26701 tttttgaaaa ggcactctta cagattgcta gtcaggtcaa ttgacatttg ttgaaactac
    26761 aacccgcgtc aggattatct tgtcgtgggt ttcttgctga tttgcttatt ttattagaaa
    26821 gtatgtcagt gatttcctta tctataagca aaaaacttga aaaaagtgaa tgtttgcgtt
    26881 atcattttca tatagaaaga aaaagaggta ttacagatgg ctattatctt accagaactt
    26941 ccatatgcat acgacgcttt ggaaccatac atcgatgcgg aaacaatgca tttgcaccat
    27001 gacaaacacc atcaaactta tgtcaacaat gccaatgcag ctttagaaaa acaccctgaa
    27061 atcggtgaag accttgaagc cttgcttgct gatgtagaat ctatcccagc tgatatccgt
    27121 caagcactta tcaacaatgg tggcggacac ttgaaccacg ctcttttctg ggaattgatg
    27181 actcccgaga aaacagctcc ttcagcagaa ctggcagcag caatcgatgc aacatttggt
    27241 tcatttgaag aattccaagc agccttcact gcagcagcaa caactcgttt tggttcaggt
    27301 tgggcatggt tggttgtcaa caaagaaggg aaacttgaag tgacttcaac agcaaaccaa
    27361 aacacaccaa tctcagaagg taaaaaacca atcttgggct tggacgtttg ggaacatgct
    27421 tactacgtga aataccgcaa cgtgcgtcct gactatatca aagctttctt ttcagtaatc
    27481 aactggaata aagtagatga attgtacgca gctgctaaat aatgatagtt ggagggaaga
    27541 attgttcttc tctttttagg ttataagatt ctggtctgac aaaatcgtca gacttttttc
    27601 atttttatga gaaacgtgct aactgctaga aattatggta gaataaagta ttaagtaatc
    27661 gtggaaaaag gatatctatg cgaaaagaaa ttgcacctga attatacaac tataacaagt
    27721 ttcctggtcc ggagttccat ttacacgggg acaaggtcga aacggaaggg atagcttttt
    27781 ccttggttga aaatatcaag gatgcctttg atgtgacgac ttttaatcag cgtttttcag
    27841 aagtcttaac caagtttgat tatatcgtgg gggactggag caacgaacag cttcgcctac
    27901 gaggttttta caaggatgac cgaacagaag aaaaacttga aaaaatcagt cgtttacaag
    27961 actacctttt agagtattgt agttatggtt gtgcctattt tgtcttagaa aatgaagccc
    28021 ctaagcgagc atcatttgac aagaaaatgc gtaagacgga agaagaaaca ccttctagaa
    28081 aaggaaagaa accgactcaa actaaacgaa agtcgaatgc agataagaaa aatagacgtc
    28141 gtcagaaaga ccagcattct cagaaagagg acaagggaca acgtcatttt gtcattcgtc
    28201 agaagtgagt agagaataag gagaagaaat gaaaccctca attcatagtt tggcacatca
    28261 aaccatgcag gaatgggtat tggagcaggg agaaaagaaa ttccgtgcag atcaaatctg
    28321 ggaatggctc taccgtaaac gtgtgcagtc atttgaagaa atgaccaacc tttccaagga
    28381 tttgattgct aagctcaatg accagtttgt ggtcaatccc ttgaaacaac gtattgtgca
    28441 agagtctgct gatggtacag tcaaatatct ctttgaattg cctgacggta tgttaattga
    28501 gactgtactc atgcgtcaac actatggttt atctgtctgt gtgaccactc aggtcggctg
    28561 taatatcggt tgtaccttct gtgcctctgg tttgattaag aagcaacgtg acctcaataa
    28621 cggtgaaatc gtagcgcaaa tcatgctggt tcagaaatac tttgctgagc gtggtcagga
    28681 tgaacgcgtc agccatatcg ttgtcatggg aatcggtgag ccctttgata attacaacaa
    28741 tgtcttgaat ttctttcgta ctatcaatga tgataaagga atggctatcg gtgctcgtca
    28801 catcatgatt tcaacctcag gtttggctca taaaattcgt gactttgctg atgaaggggt
    28861 tcaggtcaat cttgccgtgt ctcttcacgc acccaacaat gaacttcgtt caagtatcat
    28921 gaaaattaac cgtgcctttc cgattgaaaa actctttgct gctattgaat actatattga
    28981 gacaacaaac cgtcgtgtaa cctttgaata tatcatgctt aatgaagtca acgacggtgt
    29041 agaacaagcc ttggaattgg ctgaattgct caagaacatc aagaaattgt cttatgtaaa
    29101 cttgattcct tataacccag ttagtgagca tgaccaatat agccgtagtc ccaaagagcg
    29161 cgtgttggct ttctatgata cgcttaagaa aaaaggggtc aactgtgtgg ttcgtcaaga
    29221 gcatggtaca gatattgacg cagcttgtgg acaattgcgc tctaacacaa tgaaacgtga
    29281 ccgccagaag gcagtcgcag cggtaaatcc ttaatgatga agaagactta taatcatatt
    29341 ttggtctggg gagtcatttt ctatagcatt tgcattgtct atttttgctt tactcctcaa
    29401 gaacaatcta ccgtgggagt gggaactcca ggtattcagc atcttggacg cctggttttt
    29461 cttttgactc ctttcaattc tctctggaaa ctgggcgaag tgagtgacat tggacaatta
    29521 tgttggattt ttttacaaaa tgtcctcaat gtcttcttat tttttcctct gattttccaa
    29581 ctcctttatc tatttccaaa tttgcggaaa acaaaaaagg tccttctttt tagttttctt
    29641 gtgagtcttg gaatcgagtg tacgcaatta atcttggact ttttctttga tttcaatcgc
    29701 gtctttgaga ttgatgattt gtggaccaat actttgggtg gctatctggc ttggctcctt
    29761 tataaacgat tacataaaaa caagataagg aattaaaatg agtattttag aagttaaaaa
    29821 tctgagtcac ggttttggtg accgtgcaat ttttgaagat gtgtccttcc gtctcctcaa
    29881 gggagaacat atcggcctgg tcggtgccaa tggtgaagga aaatcaacct ttatgagtat
    29941 cgtgactggt aaaatgctgc cagatgaagg aaaggttgag tggtccaaat atgtgacggc
    30001 tggttacttg gatcagcact ctgtccttgc tgaaagacag tcggtgcgtg atgttctccg
    30061 tacggctttt gatgagcttt tcaaagctga agctcgtatc aatgacctct atatgaaaat
    30121 ggctgaagac ggcgcggatg ttgatgctct catggaagaa gtaggagaac ttcaagaccg
    30181 tctggagagt cgtgatttct ataccttgga tgctaagatt gacgaagtag cgcgtgctct
    30241 tggtgttatg gactttggca tggatacgga tgtaacttct ttgtcaggtg ggcaaagaac
    30301 caaggtgctt ttggcaaaac ttctccttga aaagcctgat attttgctgt tggacgagcc
    30361 gaccaactac ttggatgctg agcatattga ttggctcaag cgctatctcc aaaactatga
    30421 gaatgccttt gttctcattt cgcacgatat tccattcctc aatgacgtta tcaatattgt
    30481 ctatcatgtg gaaaatcaac agctgacgcg ttactctggt gactactacc agttccaaga
    30541 agtttatgct atgaagaaat ctcagctaga ggcagcctac gaacgccagc agaaagagat
    30601 tgcagacctc aaggactttg tggctcgtaa taaagcccgt gttgcaactc gtaatatggc
    30661 tatgtctcgt caaaagaaat tggataagat ggatattatc gaactccaaa gtgagaaacc
    30721 aaaaccatcc tttgatttca aaccagctcg tacaccaggg cgctttatct tccaagccaa
    30781 gaacttgcaa attggttacg accgtcctct tactaagcct ttaaatctta ccttcgaacg
    30841 caatcaaaag gttgcgatta ttggtgctaa tggtattgga aaaacaactc tcttgaagag
    30901 tctcttgggc attatctcgc caatcgctgg ggaagtggag cgtggagatt atttagaact
    30961 tggttatttt gagcaggaag tagaaggcgg taatcgccaa actcctcttg aagctgtctg
    31021 gaatgccttt cctgccctta atcaagcaga agtccgtgca gcccttgccc gttgtggttt
    31081 gacaaccaaa catattgaaa gccagattca agtattatca gggggagagc aagccaaggt
    31141 tcgtttctgt ctcttgatga atcgtgaaaa caacgtttta gtgctggacg agccgaccaa
    31201 ccatttggat gtggatgcaa aggatgagct caaacgcgct ctcaaagaat ataggggatc
    31261 tatccttatg gtctgccacg agccagactt ttatgaaggc tggatagacc aaatatggga
    31321 ttttaataat ttaacttaag aatgagagta aaagaaatac agtaccgaat gtggatactg
    31381 tatttttttg gtttttaaga tttaaaatcg tagtctttca ccacttcgat gctgtcgatt
    31441 gtgatagcag tagttggctt gtctttttca tctttttcgg ccttagcaat cttatccaca
    31501 acatccatac cgtcaatcac ttgaccaaag actgggtgtt tgccatctag actagggttt
    31561 ccaccttctt tgtaggcttc gataattttc tgtggatact tgcttgtagg gagtttagaa
    31621 gaggtatctg tagagttttg gttgatgaag aactggctgc cattggtgtt tggttgacca
    31681 gtattagcca tagcaagagc accgcggatg ttatacaaat aaggagtaat ctcgttcttg
    31741 aaaccagttc ctttgtcttt agtcttatcc ttgtcatgcc agatggactg accacctgta
    31801 ccgtcccctt ttggatctcc agtttggacc ataaagccat cgatgacacg gtggaaggta
    31861 ataccgttat agtagccttc tttggcgtga gtgaggaaat tttcaaccgc tagaggagcg
    31921 agtttaggga agagtttaat gcgaatatca ccttggcttg tgtggagaat cacttcggct
    31981 tcatcttcag caacttcctt agatagttgt gggaaattgg cgttttcgtt tgttaaagca
    32041 tcgtttaact ccttggcaga ttgggcagct actttggaac tttcttcagc agcaagactg
    32101 gaatcaacat aatcatcacc acgcagactg cgttggacgc tgctacaccc agctagggct
    32161 acagtagaca gtaaaagaag ggttgctagt tttttcattc tgatcctctc aaaaattcat
    32221 ttataccatt gtaccctaaa aggaagtgga tttcaaatat tagtagttta cagaactggc
    32281 ttagataata gttgggattt catcatcatc ttgaaaatct tcaacttctt ccccagtaaa
    32341 tggtttctga aaagaactta gtataaaacg ggcaattggt tcaacaatta ggaaatttag
    32401 aggaagagct gcaataaagt ttacgaacca ggcgcttaga taggtattgg gtgtgatagc
    32461 aatgccattg taaaaaagtc catagaagga catgaaagtg accagctaat tcttcttctg
    32521 aaaaatgctc atgaagggct tgatccaggt cgcaagattt cattttagaa agtccagtaa
    32581 ctcccttctt cttcaggata ttctttttca tggtattatt tagatggtca agtgagtcaa
    32641 aagaagtttc gacaagagca tacccttttt ctaccagagt ttttagatgt ttaggggcat
    32701 caataccata agtgtactca aagtattttg gaaaccagat cttaagaaag ctcgtaaagc
    32761 tagccagttc tctaaacgct aagaactagc tacaacacag catttacaac acttcatggt
    32821 tcacaccatg gggtgttttt taatgatttt aagcaaaatt cacacttaat tgaaagttat
    32881 ttaaattaga tgaaaattta ttttttgaaa aagtgggaaa acattgattc taagcgaatt
    32941 ttgaatcata ttcgaatggg agtttttaaa atcatgtttc agtggtaaaa gtaccaaact
    33001 ggattctcca tagtaaaatg atatctcctg ctagtgaatc atctactaat aagtccatat
    33061 ttcgcttggg aacgggcttg ggacttagaa gccaagtatc caactctcgt tcaggcgata
    33121 tgaagggttt gacttggtgt tctttataaa atttttctaa aatagtattc acggatagca
    33181 tctttcaaac atttatttcc tattctaaca aatttctaaa tactttaaga aatttatagt
    33241 ctgtcaagtt tttttcttga cacatgccag aaatctgcta taatagaaca tgtgctaaat
    33301 agctcagcta tttcaccaaa ataaaaaatt aaagaaatga gactttaaaa atggcagtta
    33361 aaatccgttt gactcgtatg ggttctaaga aaaaaccttt ctaccgtatc aacgtagcag
    33421 attcacgttc accacgtgac ggacgtttca tcgaaacagt tggaacttac aacccacttg
    33481 ttgctgaaaa ccaagtaact ttgaaagaag accgcgttct tgcatggttg gctaatggag
    33541 ctcaaccttc agacacagta cgtaacatcc tttcaaaaga aggcgtattg aaaaaattcc
    33601 acgattctaa attttcaaaa taagtttaaa gtaggttgac agatggatac gattgaaaat
    33661 ctcattattg cgattgtgaa acccttaatt tcacaaccag atgccttaac tatcaagatt
    33721 gaggatacac cagaattttt ggaatatcat ttgaatcttg atcaaagcga tgtgggtcgt
    33781 gtaatcggtc gtaagggtcg cactatttct gcgataagaa cgattgtcta ctctgtccca
    33841 actgaataca aaaaagtaag aatcgttatt gacgaaaaat aagaagggcg ggacggatgt
    33901 ctcgcttttt tgtgtggaat agaagatata gtaaaatgaa acaagaacag gacaaatcga
    33961 tcaggacagt caaatcgatt tctaacaatg ttttagaagt aaaggtgtac tattctagtt
    34021 tcaatatact ataaaagatt gaacgtttag gcaattccaa gactacttaa tcgaacatta
    34081 acagcagtct cggactgatg aaggtctctt tatgaagtta gtggaggaag tcggagaagt
    34141 agccgaggtt ttgaataggc gctctggtcg aaaagaaggg ataggattcg aacgagggac
    34201 ttgccagaga actggctgat atcatttact acaccgtcgc aatcgtagct attaatcata
    34261 ttgaccttac caagactgtc tttgagaaag acaaaaccgc agccgttaat taccaacata
    34321 aacataattt ggaaggatta ttgaagggaa agtagagata ttgtcccctt cctccaactt
    34381 gagaaaatcc ttggaacgtg ataaaataaa ggataaggat ttttaataat tcattatata
    34441 gaatcagtgg atttctttat gaagaggttt gaagtatcta cagaaattgg tagtctctct
    34501 gttgcttatc aaaagcaaaa gaaagtgcta gtttgtctaa acggagcagg tttgctacca
    34561 agttatgaaa atttttcact tatacttgaa aaacctcctc ctacaattgg ttatttgaca
    34621 attgattttc cgaacacagg taggagtccg attcatgacc aagctggaaa aaatctagat
    34681 aatcttgcag atgtggttta tgaagcactt gaagaattag ggatttctga atatatactt
    34741 tgtgtacata gttggagtgg aattttagct tgcaaattac tcgagaaacc aattaagtgt
    34801 cagactttag tagcaattga accgacaact aaaaaagtca tgtttgctga tttttcagaa
    34861 aatccttatc cagaaatgga agagcagatg aggctgattg acgagtgtgg tcctgaactt
    34921 tattttaaga acttaactca agcaacattt agtcctgaaa cgaataaaaa aatctgggaa
    34981 ttaatgcaag aaaaaggctt agagttggaa aatcaagatc cagaatttca gatatctgga
    35041 gagattactg aggaagattt tgagaatttg tcgatagaat ctcatgtccc tgtatttatt
    35101 ttttgtcaga cttatagaga aaaagagtac agagaatcag aatattggac ttccaatact
    35161 aaactcattt taggagggaa tcaccattat ttacaatggt cagaatcgga aaaaattgcg
    35221 gctattattc gagaattgtc agaataagat ggaaaaaagg agattacagg agacaagatg
    35281 aactacttta atgttgggaa aatcgttaat acgcagggat tacagggtga gatgcgagtc
    35341 ttgtctgtga cggattttgc agaagaacgg tttaaaaaag gagctgagct ggctttgttt
    35401 gatgaaaaag atcagtttgt ccaaacagtg accatcgcta gccaccgtaa acagaagaac
    35461 tttgacatta ttaaattcaa agatatgtac catatcaata ctatcgaaaa gtacaaggga
    35521 tacagtctca aggtcgctga ggaagatttg aatgacctag acgatggtga attttactat
    35581 cacgagatta tcggtttgga agtctatgag ggtgatagct tggttggaac catcaaggaa
    35641 atcctgcaac caggtgctaa tgatgtctgg gtggtcaaac gaaaaggcaa acgtgatttg
    35701 cttttacctt atatcccacc agtggttctc aatgttgata ttccaaataa acgggtcgat
    35761 gtggaaatct tagaagggtt agacgatgaa gattgatatt ttaaccctct ttccagagat
    35821 gttttctcca ctggagcact caatcgttgg aaaggctcga gaaaaagggc tcttggatat
    35881 ccagtatcat aattttcgag aaaatgctga aaaggcccgt catgtagatg atgagcccta
    35941 cggaggcggt cagggcatgt tgctcagagc acaacctatt ttcgattcct ttgatgctat
    36001 tgaaaagaaa aatccgcgcg ttattctcct tgatcctgct ggaaagcagt ttgatcaggc
    36061 ttatgctgaa gatttggctc aagaggaaga gctaatcttt atctgtgggc actatgaggg
    36121 ttatgatgag cgcattaaga ccttggtaac agatgagatt tccctaggcg actatgtcct
    36181 cactggtgga gaattggcag ctatgaccat gattgatgct acagttcgcc tgattccaga
    36241 agtgattggc aaggagtcta gccaccaaga tgatagtttt tcttcaggtc ttttagaata
    36301 tcctcagtac acacgtccct atgattatcg aggcatggtc gtgccagatg tattgatgag
    36361 tggccaccat gaaaagattc gtcagtggcg attgtacgag agtttaaaga aaacctacga
    36421 gcgcagaccg gatttacttg aacattatca actgacagta gaagaagaaa aaatgctggc
    36481 agaaatcaaa gaaaacaaag aataaaggag aaacctatgc aagtaatcaa acgtaatggc
    36541 gaaattgctg aatttaatcc agataagatt taccaagcca tcttgaaggc agcccaaact
    36601 gtttatgttt tgacagatga tttgcgtcaa aatcttgctc aagtcactaa gaaggtagtt
    36661 ttggatttac aagaagccaa ggtggaacgt gcgactatca gtatgattca atctatggtt
    36721 gaacatcgtt tattgggcgc aggttacatt accattgcag aacactacat ttcctatcgt
    36781 ttacaacgtg acttggaaag aagtggttat ggagatcata tcgcagttca tttacatttt
    36841 gaacaaattc gctaagaaaa aagagtggga tgaagcaact acatctcact ctttcttaaa
    36901 tctatttttt tgggctgttt ggacagttga ggggacaaat cgcaggcgtt gaatatcgct
    36961 tatacggata atccggctca catttttggc aaaatttttc acgataattt gctggccttg
    37021 ctgatcatat ttgatgatat cacctgtaaa gcttgtctca gacaagataa ggtgaacagc
    37081 ggtttgtttc tggatagcct cttcaatagt ggctgtaagg gagttggttt cagtctggtc
    37141 aggttggtca tgtccattta aaaaatcatg tattttatct agaacttgct ggaatttatg
    37201 tctcatattg gcctcccttc ttttatatca atattatata aaattttcct aaaatctaca
    37261 agattttacg aataaactaa tgaaactaaa aaaggagaag aaaatggcag aatttacatt
    37321 tgaaatcgaa gagcacttgt tgactctttc tgaaaacgaa aaaggttgga ccaaggaaat
    37381 taaccgtgtg agctttaatg gtgcccctgc aaagtttgat attcgtgctt ggagtccaga
    37441 ccatactaaa atgggcaaag ggattactct ctcaaatgaa gaatttcaaa cgatggtgga
    37501 tgcctttaaa ggcaactaat actcttcgaa aatctcttca aaccgcatca gctttgcctt
    37561 gccgtatgta tggttactga cttcgtcagt ttcatccaca acctcaaaac agtgttttga
    37621 gcagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtata agttttcaaa
    37681 ataaaaaaaa ggatattgag tcatgataac tcggtatcct tttttagtta gtaaagtaag
    37741 cctgattttt aaggcgttga agtaggggac ggctaataaa actaatagcc agaagtttgc
    37801 caaggtctgg aatgataaag ggaagaaccc ccacaacaag agctttttca aatgccattc
    37861 cagctaggaa atgcaagctg agaatcccgc cgacaaagac aagggcatca cccaagaggt
    37921 ttgcaagaaa aatcttaaca acaccactct tgctgttagt tagagaggaa gtaagtccag
    37981 agtaaacgag ataaaaccaa agatagcctg cagtagggcc aactaaagcc tgaaaaccag
    38041 ctccacctcc tgcaaagaca ggaagaccga tagcacctag aagaagatag agtccagcag
    38101 aaagtacagc ctctctcggt ctaaagacag tagcaatcaa gccgattgca aagttttgca
    38161 gagtgaaggg aacaggtcca attggaagac tgatttgtgc caaaacagca atgagagcag
    38221 ccccaatagc agggatagca taaacgtgag cttttttcaa aatagttaac ctcttttcta
    38281 atgtatagta actattatac tcatatagga gtcgatgtca accatttttt aaaaacaagg
    38341 taacaaaaac tgtaacagcc gattttcgtg actagtcaag ttggataatt tttttgttga
    38401 ttcgaaaatc attaaaaaag aagcagacat atttatatca gcttcttttg tttcgattaa
    38461 cgcatggtta caaattcttc agatgaagtt gggtgaatcg ctacagttgc gtcaaagtca
    38521 gccttggtta ctcccatttt gatagcaacg gcaaatccct gaatcatttc atcaacgccg
    38581 tagccaattc catgaagtcc gacaactttt tcttctgaac cagctgttat gagtttgaaa
    38641 cgggattctt gacggttgcg agtgcaagca gagtacatag atgcaaagct tgatttgtaa
    38701 accttgattt ggtcttgacc gtattcttta atagcttgct cttctgtcaa accaacagtt
    38761 ccgatagcag ggtgtgaaaa gacaacagtt ggaatagttg agtaatccat ttttgcagta
    38821 gtttttccgt taaagagacg ttcagatagg gtacgtccgg ccttgattgc aactggagtc
    38881 agttctttct cgcccgttac atcacctaga gcatagattc cctcaacaac agtattttgg
    38941 tattcatcca cttggataaa gccacgttcg ttcagagtca ctccagcttt ttcaagttgc
    39001 aagcccttaa cgtttggacg gcggcctgta gcccagataa cttggctagc tgtgtgacta
    39061 gtaccatctt cgaaatgaat ggtaatgccg tcagtagttt tttctaactt gacagggact
    39121 ttgtgagtgt gaagtggtaa gtttgttctt tccatttcct tgaccaaacc ttcaacgatg
    39181 taggaatcaa aaccacgtaa aggacgatcg cggcgaacaa agagatctgt cttgacacca
    39241 aaagtgtgga gtacgccagc taattcaacg gcgatataac cagcgcctag aatggcaact
    39301 gactctggaa gttcttccca ggcaaataca tcatcagaag agccacctag ctcagcacca
    39361 ggaatattag gaatacttgg atgggcacct gtagcaatca cgatatgttt agcacgaatc
    39421 agttcaccat ttacgcttac agtatgagaa tctacaaatt cagcatgacc ttcaatcaag
    39481 tctacaccgt tgcgtttaaa actgccatca taagaagaac gagcgcgatc aatgtaggat
    39541 tcacgattgc gacgtagggt tgcaaagtca aagttaagat cagtagtctt aaagccgtag
    39601 tcttctccaa attgatggaa agtctcagcg atttgtgccc cgtaccacat gattttttta
    39661 ggaacacaac cgacgttgac acaggttcca cctaatttct tttcctcaat aacggctgct
    39721 tgggctccat gttcaccagc acggttcatg gtagcgattc ctccgctacc tccaccgata
    39781 gcaatgatat catattctct cattgaaaac tcctttgtaa tcttttaaat agtagagcgt
    39841 cttttttgat agttatattt tattcttttt ttgatttgat tgcaaaaatc tgctacgcac
    39901 aaaaaattgc aaaaaagctt gccaaataag tcaagatagt gtattatata tctagtacaa
    39961 tagaaaagca aaattccgaa cgattgttta atcctgaact gtattgtttg ctggagggaa
    40021 atttggtata atagcaaagt attgtaaaaa agaaaaggag tttcattatg aagaaaaaga
    40081 atggtaaagc taaaaagtgg caactgtatg cagcaatcgg tgctgcgagt gtagttgtat
    40141 tgggtgctgg ggggatttta ctctttagac aaccttctca gactgctcta aaagatgagc
    40201 ttactcatct tgttgttgcc aaggaaggaa gcgtggcctc ctctgtttta ttgtcaggga
    40261 cagtaacagc aaaaaatgaa caatatgttt attttgatgc tagtaagggt gatttagatg
    40321 aaatccttgt ttctgtgggc gataaggtca gcgaagggca ggctttagtc aagtacagta
    40381 gttcagaagc gcaggcggcc tatgattcag ctagtcgagc agtagctagg gcagatcgtc
    40441 atatcaatga actcaatcaa gcacgaaatg aagccgcttc agctccggct ccacagttac
    40501 cagcgccagt aggaggagaa gatgcaacgg tgcaaagccc aactccagtg gctggaaatt
    40561 ctgttgcttc tattgacgct caattgggtg atgcccgtga tgcgcgtgca gatgctgcgg
    40621 cgcaattaag caaggctcaa agtcaattgg atgcaacaac tgttctcagt accctagagg
    40681 gaactgtggt cgaagtcaat agcaatgttt ctaaatctcc aacaggggcg agtcaagtta
    40741 tggttcatat tgtcagcaat gaaaatttac aagtcaaggg agaattgtct gagtacaatc
    40801 tagccaacct ttctgtaggt caagaagtaa gctttacttc taaagtgtat cctgataaaa
    40861 aatggactgg gaaattaagc tatatttctg actatcctaa aaacaatggt gaagcagcta
    40921 gtccagcagc cgggaataat acaggttcta aataccctta tactattgat gtgacaggcg
    40981 aggttggtga tttgaaacaa ggtttttctg tcaacattga ggttaaaagc aaaactaagg
    41041 ctattcttgt tcctgttagc agtctagtaa tggatgatag taaaaattat gtctggattg
    41101 tggatgaaca acaaaaggct aaaaaagttg aggtttcatt gggaaatgct gacgcagaaa
    41161 atcaagaaat cacttctggt ttgacaaatg gtgctaaggt catcagtaat ccaacatctt
    41221 ccttggaaga aggaaaagag gtgaaggctg atgaagcaac taattagtct aaaaaatatc
    41281 ttcagaagct accgtaatgg tgaccaagaa ctgcaggttc tcaaaaatat caatctagaa
    41341 gtgaatgagg gtgaatttgt agccatcatg ggaccatctg ggtctggtaa gtccactctg
    41401 atgaatacga ttggcatgtt ggatacacca accagtggag aatattatct tgaaggtcaa
    41461 gaagtggctg ggcttggtga aaaacaactg gctaaggtcc gtaaccaaca aatcggtttt
    41521 gtctttcagc agttctttct tctatcgaag ctcaatgctc tgcaaaatgt agaattgccc
    41581 ttgatttacg caggagtttc gtcttcaaaa cgtcgtaagt tggctgagga atatttagac
    41641 aaggttgaat tgacagaacg tagtcaccat ttaccttcag aattatctgg tggtcaaaag
    41701 caacgtgtag ccattgcgcg tgccttggta aacaatcctt ctattatcct agcggatgaa
    41761 ccgacaggag ccttagatac caaaacaggt aaccaaatta tgcaattatt ggttgatttg
    41821 aataaagaag gaaaaaccat tatcatggta acgcatgagc ctgagattgc tgcctatgcc
    41881 aaacgtcaga ttgtcattcg ggatggggtc atttcgtctg acagtgctca gttaggaaag
    41941 gaggaaaact aagatgcaga atctgaaatt tgccttttca tctatcatgg ctcacaagat
    42001 gcgttctttg cttactatga ttgggattat tatcggtgtt tcatcagttg ttgtgattat
    42061 ggctttgggt gattccctat ctcgtcaagt caataaagat atgactaaat ctcagaaaaa
    42121 tattagcgtc tttttctctc ctaaaaaaag taaagatggg tcttttactc agaaacaatc
    42181 agcttttacg gtttctggaa aggaagagga agttcctgtt gaaccgccaa aaccgcaaga
    42241 atcctgggtt caagaggcag ctaaactgaa gggagtggat agttactatg taaccaattc
    42301 aacgaatgcc atcttgacct atcaagataa aaaggttgag aatgctaatt tgacaggtgg
    42361 aaacagaact tacatggacg ctgttaagaa tgaaattatt gcaggtcgta gtctgagaga
    42421 gcaagatttc aaagagtttg caagtgttat tttgctagat gaggaattgt ccattagttt
    42481 atttgaatct cctcaagagg ctattaacaa ggttgtagaa gtcaatggat ttagttaccg
    42541 ggtcattggg gtttatacta gtccggaggc taaaaggtca aaaatatatg ggtttggtgg
    42601 cttgcctatt actaccaata tctcccttgc tgcgaatttt aatatagatg aaatagctag
    42661 tattgtcttt cgagtgaatg ataccagttt aaccccaact ctgggtccag aactggcacg
    42721 aaaaatgaca gagcttgcag gcttacaaca gggagaatac caggtggcag atgagtccgt
    42781 tgtatttgca gaaattcaac aatcgtttag ttttatgacg acgattatta gttccatcgc
    42841 agggatttct ctctttgttg gaggaactgg tgtcatgaac atcatgctgg tttcggtgac
    42901 agagcgcact cgtgagattg gtcttcgtaa ggctttgggt gcaacacgtg ccaatatttt
    42961 aattcagttt ttgattgaat ccatgatttt gaccttgtta ggtggcttaa ttggcttgac
    43021 aattgcaagt ggtttaactg ccttagcagg tttgttactg caaggtttaa tagaaggtat
    43081 agaagttgga gtatcaatcc cagttgccct atttagtctt gcagtttcgg ctagtgttgg
    43141 tatgattttt ggagtcttgc cagccaacaa ggcatcgaaa cttgatccaa ttgaagccct
    43201 tcgttatgaa tgagatcaac aagatggaca ctcgtctatc ttgtttttgt atggatttcc
    43261 ctatcgaaat tcattaaaaa tgtgatataa tgaagtgtta gaaaaacagg tttcatttgc
    43321 ctggaaagga aaaattatgt ctgaaaaaaa tttttatatt acaacgccga tttactatcc
    43381 atctgggaaa cttcatatcg gttctgccta cacaactatc gcatgtgatg tcctagcacg
    43441 ttacaaacgc ctgatgggct acgatgtatt ttatctgaca ggtcttgatg aacatggtca
    43501 gaaaatccag cagaaagcgg aagaagctgg tattacacct caagcctatg ttgatggaat
    43561 ggcggttgga gttaaagaac tctggcaatt actagatatc tcatacgata aatttatccg
    43621 tacaaccgat gactaccatg aaaaagttgt cgcacaggtc tttgaacgct tacttgctca
    43681 agatgatatc tacttgggtg aatactctgg ttggtattca gtatcagacg aagaattctt
    43741 tacagaaagc cagctggcag aagttttccg tgatgaagct ggaaatgtga ctggtggtat
    43801 tgctccatca ggtcatgagg ttgaatgggt ttctgaagaa tcatacttcc ttcgccttag
    43861 caaataccaa gaccgtttgg tcgaattttt caaagctcat cctgaattta tcacgccaga
    43921 tggtcgcctt aatgaaatgc tacgcaactt catcgagcca ggcttggaag atttggcggt
    43981 atctcgtaca acctttacat ggggagtgcc tgtcccatca aatccaaaac acgttgtcta
    44041 cgtttggatt gatgcccttc ttaactatgc gacagctctt ggctacgctc aagacgaaca
    44101 tggtaacttt gacaagttct ggaatggaac agtcttccat atggtaggaa aagatatcct
    44161 tcgcttccac tctatctact ggccaatcct tcttatgatg ttggatgtta aattacctga
    44221 tcgtttgatt gcccatggtt ggtttgtcat gaaagacgga aaaatgtcta agtcaaaagg
    44281 gaatgtcgtt taccctgaaa tgttggtaga gcgttatgga ctagatccac ttcgttacta
    44341 cctcatgcgt aaccttccag ttggttcaga cggaaccttt actcctgaag actatgtcgg
    44401 ccgtatcaac tatgaattgg ctaatgacct tgggaacctc cttaaccgta cggtttccat
    44461 gattaataag tactttgatg gacaaatccc tgcctatgta gaaggtgtga ctgaatttga
    44521 tcatgttctt gctgaggttg cagaacaatc aatcgcagac ttccatacac acatggaagc
    44581 agttgactat ccacgtgcgc ttgaagcagt ctggactctg atctctcgta ccaataaata
    44641 catcgatgag accgcaccat gggtcttggc caaggatgaa gctcttcgtg accaattggc
    44701 aagtgtcatg agccacttgg cagccagcat tcgtgtagtt gctcacttga ttgaaccatt
    44761 tatgatggaa actagtcgtg cagttttgac tcaacttggt ttggaagaag tttctagtct
    44821 tgaaaacttg agtttggctg acttcccagc agatgtgact gtagttgcca aaggaacacc
    44881 tatctttcca cgtctaaata tggaagaaga aatcgcctat atcaaggaac aaatggaagg
    44941 caataaacca gcagtcgaaa aagaatggaa tccggacgca gttgagctca aactaaacaa
    45001 ggatgaaatc aagtttgaag actttgacaa ggttgaaatc cgtgtcgcag aagtcaaaga
    45061 agtgtctaaa gtagaaggtt cagataagtt gcttcaattc cgcttggatg ctggtgatgg
    45121 agaagatcgt cagattcttt caggaattgc aaaatactat ccaaatgaac aagaattggt
    45181 cggcaagaaa gttcaaatcg ttgctaacct caaaccacgt aaaatgatga aaaaatatgt
    45241 cagccagggt atgattctct cagctgaaca tgatggcaaa ttaacccttc tcacagttga
    45301 tccagctgta ccaaatggaa gtgtgattgg gtaaaagtag acaggactag ttcagactag
    45361 ttctgttttt ttatttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
    45421 gttgctcaaa acactgtttt gaggttgtag atagaactga cgaagtcagc tcaaaacatg
//
LOCUS       DAVHSL010000012        45467 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000012 DAVHSL010000000
VERSION     DAVHSL010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45467
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.012"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(184..1818)
                     /locus_tag="VVR39_000667"
     CDS             complement(184..1818)
                     /locus_tag="VVR39_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030199.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1799..2548)
                     /locus_tag="VVR39_000668"
     CDS             complement(1799..2548)
                     /locus_tag="VVR39_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030200.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            2727..4181
                     /locus_tag="VVR39_000669"
     CDS             2727..4181
                     /locus_tag="VVR39_000669"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU6030201.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4271..6889)
                     /gene="alaS"
                     /locus_tag="VVR39_000670"
     CDS             complement(4271..6889)
                     /gene="alaS"
                     /locus_tag="VVR39_000670"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU6030202.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(6911..7396)
                     /locus_tag="VVR39_000671"
     CDS             complement(6911..7396)
                     /locus_tag="VVR39_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU6030203.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFQLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7671..7910)
                     /locus_tag="VVR39_000672"
     CDS             complement(7671..7910)
                     /locus_tag="VVR39_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030204.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSTMKIWDKKKNGSKKKYILKK"
     gene            complement(8179..9249)
                     /locus_tag="VVR39_000673"
     CDS             complement(8179..9249)
                     /locus_tag="VVR39_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6030205.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9246..10019)
                     /locus_tag="VVR39_000674"
     CDS             complement(9246..10019)
                     /locus_tag="VVR39_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030206.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(10016..10822)
                     /locus_tag="VVR39_000675"
     CDS             complement(10016..10822)
                     /locus_tag="VVR39_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030207.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10803..11960)
                     /locus_tag="VVR39_000676"
     CDS             complement(10803..11960)
                     /locus_tag="VVR39_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030208.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12121..13026)
                     /gene="murB"
                     /locus_tag="VVR39_000677"
     CDS             complement(12121..13026)
                     /gene="murB"
                     /locus_tag="VVR39_000677"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU6030209.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13138..13890)
                     /locus_tag="VVR39_000678"
                     /pseudo
     CDS             complement(13138..13890)
                     /locus_tag="VVR39_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13900..14631)
                     /gene="budA"
                     /locus_tag="VVR39_000679"
     CDS             complement(13900..14631)
                     /gene="budA"
                     /locus_tag="VVR39_000679"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU6030210.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAIDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14773..16044
                     /locus_tag="VVR39_000680"
     CDS             14773..16044
                     /locus_tag="VVR39_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU6030211.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(16064..16879)
                     /locus_tag="VVR39_000681"
     CDS             complement(16064..16879)
                     /locus_tag="VVR39_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6030212.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKAQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(17036..17689)
                     /gene="phoU"
                     /locus_tag="VVR39_000682"
     CDS             complement(17036..17689)
                     /gene="phoU"
                     /locus_tag="VVR39_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6030213.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17701..18459)
                     /gene="pstB"
                     /locus_tag="VVR39_000683"
     CDS             complement(17701..18459)
                     /gene="pstB"
                     /locus_tag="VVR39_000683"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6030214.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18472..19275)
                     /gene="pstB"
                     /locus_tag="VVR39_000684"
     CDS             complement(18472..19275)
                     /gene="pstB"
                     /locus_tag="VVR39_000684"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6030215.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19286..20170)
                     /gene="pstA"
                     /locus_tag="VVR39_000685"
     CDS             complement(19286..20170)
                     /gene="pstA"
                     /locus_tag="VVR39_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6030216.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20160..21077)
                     /gene="pstC"
                     /locus_tag="VVR39_000686"
     CDS             complement(20160..21077)
                     /gene="pstC"
                     /locus_tag="VVR39_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6030217.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(21077..21955)
                     /gene="pstS"
                     /locus_tag="VVR39_000687"
     CDS             complement(21077..21955)
                     /gene="pstS"
                     /locus_tag="VVR39_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU6030218.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22529..23833)
                     /locus_tag="VVR39_000688"
     CDS             complement(22529..23833)
                     /locus_tag="VVR39_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU6030219.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLHYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23834..24607)
                     /locus_tag="VVR39_000689"
     CDS             complement(23834..24607)
                     /locus_tag="VVR39_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU6030220.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRIYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24597..24875)
                     /locus_tag="VVR39_000690"
     CDS             complement(24597..24875)
                     /locus_tag="VVR39_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU6030221.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24875..25276)
                     /locus_tag="VVR39_000691"
     CDS             complement(24875..25276)
                     /locus_tag="VVR39_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU6030222.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25486..26103)
                     /locus_tag="VVR39_000692"
     CDS             complement(25486..26103)
                     /locus_tag="VVR39_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU6030223.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(26093..26866)
                     /locus_tag="VVR39_000693"
     CDS             complement(26093..26866)
                     /locus_tag="VVR39_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU6030224.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26877..27614)
                     /locus_tag="VVR39_000694"
     CDS             complement(26877..27614)
                     /locus_tag="VVR39_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU6030225.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(27619..28749)
                     /locus_tag="VVR39_000695"
     CDS             complement(27619..28749)
                     /locus_tag="VVR39_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU6030226.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28833..29222)
                     /locus_tag="VVR39_000696"
     CDS             complement(28833..29222)
                     /locus_tag="VVR39_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6030227.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29238..29621)
                     /locus_tag="VVR39_000697"
     CDS             complement(29238..29621)
                     /locus_tag="VVR39_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU6030228.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29622..30410)
                     /locus_tag="VVR39_000698"
     CDS             complement(29622..30410)
                     /locus_tag="VVR39_000698"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU6030229.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(30403..31338)
                     /locus_tag="VVR39_000699"
     CDS             complement(30403..31338)
                     /locus_tag="VVR39_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU6030230.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31468..31644)
                     /locus_tag="VVR39_000700"
     CDS             complement(31468..31644)
                     /locus_tag="VVR39_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU6030231.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31784..32491)
                     /locus_tag="VVR39_000701"
     CDS             complement(31784..32491)
                     /locus_tag="VVR39_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU6030232.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32642..33670
                     /gene="queA"
                     /locus_tag="VVR39_000702"
     CDS             32642..33670
                     /gene="queA"
                     /locus_tag="VVR39_000702"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU6030233.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34331..35458)
                     /locus_tag="VVR39_000703"
     CDS             complement(34331..35458)
                     /locus_tag="VVR39_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6030234.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(36189..36740)
                     /locus_tag="VVR39_000704"
     CDS             complement(36189..36740)
                     /locus_tag="VVR39_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030235.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(37090..37914)
                     /gene="nadE"
                     /locus_tag="VVR39_000705"
     CDS             complement(37090..37914)
                     /gene="nadE"
                     /locus_tag="VVR39_000705"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU6030236.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIVVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQELGADPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(37911..39371)
                     /locus_tag="VVR39_000706"
     CDS             complement(37911..39371)
                     /locus_tag="VVR39_000706"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU6030237.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ETHKNCVFLVDTYDTLRIGVPAAIQVACELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(39487..39975)
                     /locus_tag="VVR39_000707"
     CDS             complement(39487..39975)
                     /locus_tag="VVR39_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030238.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(39965..40174)
                     /locus_tag="VVR39_000708"
     CDS             complement(39965..40174)
                     /locus_tag="VVR39_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6030239.1"
                     /translation="MVKNLKLKLARVELDLTQGQLADAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(40560..41288)
                     /locus_tag="VVR39_000709"
     CDS             complement(40560..41288)
                     /locus_tag="VVR39_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030240.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(41304..42182)
                     /locus_tag="VVR39_000710"
     CDS             complement(41304..42182)
                     /locus_tag="VVR39_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030241.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGQVG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRSLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTELDILILDEPTNGLD
                     IESSQIVLAVLKNLALHENVGILISSHKLEDIEEICERVLFLESGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDF
                     KTKKETLKDIYLNRSK"
     gene            complement(42517..43245)
                     /locus_tag="VVR39_000711"
                     /pseudo
     CDS             complement(42517..43245)
                     /locus_tag="VVR39_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(43491..43802)
                     /locus_tag="VVR39_000712"
     CDS             complement(43491..43802)
                     /locus_tag="VVR39_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030242.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(43817..45103)
                     /locus_tag="VVR39_000713"
     CDS             complement(43817..45103)
                     /locus_tag="VVR39_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6030243.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT        13687 a        10202 c         8385 g        13193 t
ORIGIN      
        1 tgaaattgaa aaatatccca ataaataaac tataaacaac aataatagaa ctatattata
       61 tttcttattc aaaacattcc tccctatatt tttgattacc aatcttaatc atttacaact
      121 acattctaac aaactataaa agcgtttgtc gaattgaatt tatcaagcaa gcaaccaact
      181 atctcatctt ttttctattt ctgccaatat gcgtgacagg taataatgat agccaaaaat
      241 agcaagagca agcaagacga taagagctcc tactcccaag ttgatggcaa ggatagggga
      301 gagagactga accaagaata tgctcccaat tacaagggcc atcaggattg cactataaat
      361 aaacaataaa actatggcga ctatgccatt tgaacgattc accaggtccg taatgctact
      421 ccaattggtt gacagatttt taacgtcctt aaagtaatgg tggcaagaaa ggatgacact
      481 ggcaatgatc cagactacaa gaaggtaaat catcgaaagg atggacaagc ctagatatag
      541 agaaagaccg agcaaagtca gaactggtaa aaaggactga acagcaaaga taatccaaaa
      601 tttcactttc acataacgag caaagtcaaa gggtaaactc ttcagaaaat caacattttc
      661 cctctccaag gacaaggcaa ttgaatgcag gctggtgata ttgttattga caactgctat
      721 aaacactcct acaaaaaaca agggtaacca gtatggagga tgaatgtctg gaactatctg
      781 agaatctcgg attttggaaa tcagactgat catcatgaga taaggaagga aagcacttgt
      841 aaaaagcact gtaatcacac cagtcccctg tcccaagagg gtgaggtggt agcgtaaaac
      901 catacggaaa aagccctttt tagtagttga aatcctctcc ttgctgcgac gttctttttt
      961 gaccttctcc tcactgttaa gcaggatcac gtcataaaaa cgaggaagga ccttcttttt
     1021 ggtcagataa agcaggaaga gagttagtcc tatccaagcg agcagaccca ctaaggcttc
     1081 tgtcgaaaaa ggctccactg ctattttgta aaagatatga agaggataaa ggagaaatgg
     1141 aatgtctcta actttgtcaa caatacttcc aaaagtcgac tgaagaaaga agataaatat
     1201 taaaggtatg agaactccta tcccaatcat cacattcgaa aaaatagact gatactttct
     1261 gaagacccta gtctgagcca agaaatgtac tgccactacc gtcactaaag taacagagac
     1321 aaataataag gtcaaggaca gtagcatcaa aggcaaaccc agccaaagag aaggagctag
     1381 actaatatag agggctagaa aataagctag gattggtaca attccagtta gagctggcaa
     1441 gaggacagac agacctttgg ccattataat ctctgattct ttaaaggcat agggcctata
     1501 ggaggccagg tccttactct cataaaagac attgtaaaag gcagtgaaag aagttgaaaa
     1561 ggccagcacc agtaaaatag caaccatcga gctaaaataa ataggcattt cctcaaaagg
     1621 aaaatgaatg gctatattac taaaacagat gagcatcaag agactggaaa aaatgtaaga
     1681 acttaggact ctagcagaaa catttacttt tttcccagga ttcttagcct gcttctttcg
     1741 tagattagcc agattagctt cttgagatga atagaggata ttgatatcaa ctaatttttt
     1801 aatgaccttg agacgcatcc gcaacctcct cttttctacc agcaagacta aggtagatac
     1861 tttccaaaaa ctggtctggg tggtctttcc tcaagttctc tacactacca caatagatca
     1921 aatgcccctt tttcaaaata gcaatccgat cacagacttg ctcggctacc tcaaggacat
     1981 gagttgaaaa caagaccgtc ttgccttttt gtgcatgttc cttcatcatt tgcttcaaat
     2041 caaaggcggc ctggggatcc aaaccagtca agggttcgtc caaaacccaa atatcaggag
     2101 cagacaagag tgccccaatg acaaagactt tctgacgcat tccgtgagaa agagtttcaa
     2161 taacctgata gcggttttca gcaaaatcaa aaacgttcaa tagcctagct agactagtct
     2221 ccaagtcaga gctagtcaga tcataggatg aagcgatcaa ttcccaaaat tcattggccg
     2281 ttaagcgtaa aaataagtca ggcgagtctg ctacgtagcc aatctttcgt ttgatcgcca
     2341 agcgattttc cgataactcc tgaccgtcta ccaaaatacg accactgctg ggtgaaatga
     2401 tactgactag ggattttatg gtggtcgatt ttccagcccc attatgacca atcaagccca
     2461 taatctctcc attttcaatc tgcaaattga gattactcaa ggcctcttta tcaccataca
     2521 acttactaac attttgaaat tcaatcatgg gacaactcct atctttatct gtattataca
     2581 tcgctatact agcactttga tacaaaaaaa tcaatacttt attttaagta gttaaaatag
     2641 tttccttcta tcttacgcaa acgtttgcgc cgagagatac tttatgatag aataaagaac
     2701 aagattgaca agtaagagga aacatcatgc aaaatcaaac actcatgcaa tactttgaat
     2761 ggtatctgcc ccacgacggt caacactgga cgcgtctggc tgaaaatgct ccacacctag
     2821 ctcatctggg gatcagtcac gtctggatgc caccagcctt caaggcaacc aacgaaaaag
     2881 atgtcggcta tggggtctat gacttatttg acttaggaga gttcaaccaa aaagggactg
     2941 tccgcaccaa gtatggtttc aaagaagact atcttcaagc cattcaagcc cttaaagaac
     3001 agggaattca acctatggcc gatgtagttc tcaaccacaa ggctgctgcc gataacaggg
     3061 aagcctttca ggttatcgaa gttgatcctg tagaccgtac agttgaactt ggagaaccct
     3121 tcaccatcaa tggctggact agttttacct tcgatggtcg ccaagatacc tataatggct
     3181 tccactggca ttggtaccac ttcaccggta cagactacga tgccaaacgc agtaaatctg
     3241 ggatttatct gatccaaggg gacaacaagg gctgggctaa cgaggaattg gtcgataacg
     3301 aaaacggaaa ctacgactac ctcatgtatg ccgacctaga ctttaaacat cctgaagtca
     3361 tccaaaacat ctatgactgg gctgattggt tcatggaaac gactggtgta gctggtttcc
     3421 gtttggatgc cgttaagcat attgactctt tctttatgcg caacttcatc cgcgatatga
     3481 aggaaaaata cggtgacgat ttctatgttt ttggtgaatt ttggaaccca gacaaggaag
     3541 ccaatctgga ctatctcgaa aaaacggaag aacactttga ccttgtcgat gttcgtctcc
     3601 accagaatct ctttgaagcc agtcaagctg gcgcaaacta tgaccttcgt ggcattttca
     3661 cagatagcct ggttgaactc aagcctgaca aggctgtgac ttttgtcgac aaccacgata
     3721 cccaacgagg acaagccctt gagtctaccg ttgaagaatg gttcaagcca gcagcctatg
     3781 ccctcatttt gttacgccaa gacggccttc catgtgtctt ttacggagac tactatggga
     3841 tttcaggcca gtatgctcaa gaagatttca aagaaatcct tgaccgcctc ctagccatcc
     3901 gaaaagactt ggcctatgga gaacaaaatg actactttga ccatgctaac tgtatcggtt
     3961 gggtacgttc aggtgctgaa aatcaatccc caatcgcagt ccttatctca aatgaccaag
     4021 aaaacagcaa gtcaatgttt gtcggtcaag aatggactaa tcaaaccttt gtagatttac
     4081 ttggtaacca ccaaggtcaa gttacaattg atgaggaagg ttatggacaa ttccctgtct
     4141 cagctagatc cgtaagtgtc tgggcagtca ataccatcta atagctcata ataaccaagc
     4201 taggtccaag cggatttggc ttttttgtat tcacaaaaag acctacccaa atggatagat
     4261 ctttacttga ttacaattta cctgctactg catccaacaa ttcttggatc ttaggttggt
     4321 tgcttcctcc tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg
     4381 ctaattcttt gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat
     4441 tgactttgtc accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc
     4501 agttatctgc aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt
     4561 aacgatgacc gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg
     4621 ctttttcttt caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt
     4681 ctaccttgtg aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa
     4741 gagcatcctc ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac
     4801 ggcgagttcc tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag
     4861 tgttgccaac atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac
     4921 gaacttcctt gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt
     4981 caatatccgt ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct
     5041 gttcaatcgc acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa
     5101 ggaattcaac ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa
     5161 gggcagcgtg aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc
     5221 tatcaattgc caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat
     5281 gaagggcttg accatttggg gctttctgaa cattggtcac agtagccaca atcttacctg
     5341 actcatccaa gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg
     5401 tttccgcaaa gataagagag gcagttcctt ctgaaacagc tcctacttct gcattgtcag
     5461 caacgatagc taccaattta gaagacaatt ggctagtatt gtagttgaag acactttcta
     5521 cagtgatgtt ttgaagagtt tcattttgca tacccattga gccacccttg acagctgacg
     5581 cacgcgcgcg ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca
     5641 taccagcttc ttcagcaatt tcttcagtca attcaactgg gaatccgtat gtatcataga
     5701 gtttaaagac atcttgacca gcaatgacag attgaccttt ttctttcaag tctgccacaa
     5761 tgccttgggc aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct
     5821 taacgatttt ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga
     5881 tttttccaac agttggaaca agtttgtaaa ggaaaggctc gttgataccc aatttttgac
     5941 catgcataga agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg
     6001 gaagggcacc atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga
     6061 agctcatgtt gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga
     6121 taatcggcat gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca
     6181 aacgctccaa accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac
     6241 gaggaacagc agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac
     6301 ggtcgttttc aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt
     6361 ccccacggtc aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga
     6421 agttgtcctc aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt
     6481 aagaatcttt atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc
     6541 attcagggct tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc
     6601 cgatagagaa gttccccagc atttcaaaca tggtatggtg acgcgcagtc ttccctacgt
     6661 tttcgatgtc gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga
     6721 taatggtccc gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag
     6781 ttgggtcatt tacaggaacc aaacttactg atggttctac tgagtgagct ttggtcgccc
     6841 agaaatcaag ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt
     6901 atttacttgt ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga
     6961 gggaaatgac taggtctgca taagcgtcct caagaaccgt tacggtatag gtagaggtca
     7021 gatggaagag ttccttctta atttccgcaa tcagctgatc gcgatcatcc agcaattgga
     7081 aattcaaatc ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat
     7141 ctcgccagaa ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct
     7201 caaaacgagg aagcaaggtc aagatttctt tactaatctg actgacttgt tcaccagccg
     7261 catcatagat ggtaaaggtt ttaggaatct taaaaaatga tccctccacc tgataggcaa
     7321 tttctcccct gtcattcttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga
     7381 caagaaatgt tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc
     7441 gaaaaaccgc ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt
     7501 gtatgattga gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg
     7561 actaagacaa gtgaaaatca attctcaact ttcttattat atcgtttttt taatcttgcg
     7621 tcaactggaa atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc
     7681 aggatatatt ttttcttact gccatttttc tttttatccc aaattttcat agtactaaac
     7741 acagctacta gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt
     7801 gttaggtatt gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca
     7861 atcataaagg ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc
     7921 cgctttctgt aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca
     7981 agctgtactt gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat
     8041 actactaggc aagcaaataa gcaaataaac aaataaacaa ataaacaact agaatagaaa
     8101 aagatagggc tctaaaaact gacttctatt ccttaaaaac gaaccagctt gactgattcg
     8161 tcttcttacg tttatctcct acttccgata cattttaaac tgtaggaaga ggtcgctata
     8221 tttccctgtc catttatggt caaatttctc ataaacttct aggtgtttca tggtttcaac
     8281 atcgggatag aaggccttat cttcctttgt ttcctctggg agcaattcct tcgctggtag
     8341 gtttggtgtt gaatagccga catactccgc attttggaga gcattttcag gtttcaacat
     8401 aaagttgata aaggcataag ctgagttttg gtttttaact gttttgggaa tgaccatatt
     8461 gtcaaaccaa agattgctgg cctctgtcgg taccacataa cgtagatttt catttttttc
     8521 taacatttgg ctggcttcac cagagaaggt cacgccgatt gcaacattat tctgaatcat
     8581 atagcccttc atctcgtccg caacgatagc cttgatattt ggagtcagtt tgtagagctt
     8641 atccactgtc tcttccaact gctgcagatc cttggagttg aggctgtagc cgagggaatt
     8701 gagtcctagt cccagcacct cacgcgcccc atcaaagagc atgatagaat tcttatactc
     8761 cggcttccaa aggtcatccc aatgctcagg cgcttcatct accatggttt cgttgtagac
     8821 aattcctaag gttccccaga agtaagggat ggagaattta ttacctgggt caaaggactg
     8881 gttgagaaac tctggtccga tattttcgat tccttcaatt tttgaataat caagcggaac
     8941 caagaggtct tcgtccttca tcttgttaat catgtattca cttggaatgg caatatcgta
     9001 ggtcgttcca ccctgcttta tcttagtgta catggcttcg ttggagtcaa aagtctcgta
     9061 ctgaacttga attcctgttt cttctgtaaa ctgagtcaag agttcaggat cgatatagtc
     9121 tccccagtta tagataacca atttttgact atctcgacta ttgattttac tatctaaatg
     9181 agtcgcaatt ccccacaaga caaggataat cgctgcaatt cctgctaaaa atgaatagat
     9241 ttttttcatg cttgctcctc cttctcacga gagataaagt aataacctac aactaggata
     9301 atactaaaga gaaagactag agcagacagg gcattgattt ctaaggaaat ccccttgcga
     9361 gcacgagagt aaatctcgac tgatagggtt gaaaagccat ttcctgttac aaagaaggtc
     9421 acggcaaagt catctaacga ataggtgaag gccatgaaat aaccagtaat gatagacgga
     9481 gtcaggtaag gaagcatgat ttccttgaac atctgaaatt gactagctcc caagtcatag
     9541 gccgcatgaa tcatgtcgcc attcatttcc ttgagtcgag gcaagaccat caagaccacg
     9601 ataggaatgg agaaggccac gtgactagat agaacggtca aaaagccaag tgaaaacttg
     9661 agttgggtaa agagaatcaa gaagctagca ccaatcataa cgtcaggcgc aaccatgagg
     9721 atattattga gtgatagaaa ggcttcttgg tatttcttac gagactggta gatgtaaatg
     9781 gcaccaaaag tcccgataat ggtcgctatc aaggctgata ggaaggccaa gaaaaatgtc
     9841 tgagccaaaa tcagcatgag tctcccatct ccaaacatgg tttcaaagtg agtccagcta
     9901 aaacctgtaa agctattcat atcatcacca gcattaaagg catagccaat caagtaaaag
     9961 ataggcaggt agaggaccag aaagaccagt cccagataaa ggttggcaaa ttttttcatc
    10021 gttctctcct ttccttagtc acccacatgg tgatgaacat ggtcaggatg agaatcacac
    10081 cgatggttga acccatacca tagttgtcat tggttagaaa attctgctca atagccgtcc
    10141 ccaaggtgat aacgcggttc ccaccaatca aacgggtcag catgaagaga ctcaaacttg
    10201 ggataaagac cgactgaacc ccacttcgca caccgttcat agatagaggg aagatgacat
    10261 gacggaaggt ctcccactta gttgcaccaa ggtcataact agcattgatg agattattat
    10321 ccatgtcgtc taagacattg aaaatcggca aaatcataaa ggggagctcg atgtagcttg
    10381 cgacaaagat aaaggaaaaa tcggtaaaaa gcaactgttg tgaaccaatt ccgataaatt
    10441 ccaagaattg gttaatagag ccattttgac caaaaatccc gataaaagca taggctttaa
    10501 ggagcaaatt gatccaggta ggaaggataa tcagcatgag ccagagttga cggtgcttga
    10561 gacgggtcaa aaagagggct gttggatagc tgataagcaa ggtcacaaag gtcacaatcc
    10621 ctgcataaag cactgagttg aaactcattt tgaggtaggt caagttttgt gacgcaaagt
    10681 aagatttata attttctaaa ctaaactggc cttcaatgtt gaaaaaggat tgtccgaaaa
    10741 tcaagaccaa gggtgccaat acaaagaggg caatccaaag catgtagggc actacaaaga
    10801 gtttagagct tgttttcttc atctctttcc tcctcgatcg cattgatcag acctgcttct
    10861 tgctcttcga tttccacgta ttcttcgata cgagcatcga actcttcttc ggtttcattg
    10921 agacgcatga tgtggatgtc ttctggttca aagtccagac cgatttcctc acccacgatg
    10981 gccttacggg ttgagtggat catccattca tttccaagtt cgtcataggc gataatttca
    11041 taatgcaccc cacggaagag ctgggtatcg accttaactt gaagcttgcc ttcttcagga
    11101 agggtaatgc gcaagtcctc tggacgaata acgacctcaa caggttcatt tggcttcatc
    11161 ccaccatcaa ccgcttcaaa gcgtttgccg ttaaattcga ccaagtagtc ctcaatcatg
    11221 gtacctggca agatgtttga ctccccgata aaggtggcaa caaagtggtt gattggctca
    11281 tcgtagatgt ccacaggggt tccagactgg acaatctcgc catcattcat aacgaaaatc
    11341 cagtcactca tggcaagagc ttcttcctga tcgtgagtga caaagacaaa ggtaatgccc
    11401 aatcgttgtt gcagttcacg cagttcgtac tgcatgtctg ttcttaattt caagtccagc
    11461 gctgacaagg gctcatccaa caaaaccaca cggggttggt tgatgatagc acgggcgata
    11521 gccacacgct gacgttgtcc tccagaaagt ttgcggatgg aacgtttttc ataaccttcc
    11581 aactgaacca tcttgagaac ttccgctaca cgttgctcga tttctttctt atcaatgtta
    11641 cgcaagcgaa gtggaaaggc aacattttca aacacattca tatgtgggaa caaggcatag
    11701 gattggaaga cagtatgtac gtcgcgcttg ttggttggaa tatcattgat acgaacaccg
    11761 tctagcatga tatctcctgt cgtcgcatcc agtaaacctg caataatgtt taggatagtt
    11821 gatttccccg aaccagatgc acctagaagg gtgtagaatt tcccttcttc caactcaaag
    11881 ttgatgtctt tgagaacctt ggtgttgctg tcttcaaaaa ctttagagac gtttttgaat
    11941 tcgataattg gttttttcaa ttggcataaa ttccttcttt ttcatagatt aaccgatcgg
    12001 ggctctgtca ggtccccact acctcttgca gggagtaaaa ccacctgcat acatcttcgc
    12061 taccgatagg ctttcacccc cctttccatg acatagcagc agcttttcaa atacagcttc
    12121 ctacttgctt tcacccaaga tccggacttc tctttcaagc gtaatacctg agtgttcctt
    12181 gactttttcg ataaccgatt ggatcaagtc ctcgtagtct ttggccgttc catctgcgac
    12241 attgatcata aatcctgcat gcttttctga cacttctacg ccaccgatac gatagccttt
    12301 caagccagct tctgaaatta actgacctgc aaaatgcccg actggacgct taaagaccga
    12361 gccacaagat gggtattcca aaggttgctt gagttcacgt aggtgcgtca agcggtccat
    12421 ttcctgcttg ataacctgat gggttcctgg ggctagggca aatttaactg acaagacaac
    12481 tgcaccagac tcctgaatag ctgaatggcg gtaaccaaaa gccaagtctt tagcagacag
    12541 ggtttcgatt tctccatcct tggtcaagac cttacaagac tgcaatatgt gagcaatctc
    12601 gccaccatag gcacccgcat tcataaagac agcaccgcca acgcttcctg gaataccaca
    12661 agcaaactca aagccagtca aactatgacg gagggcaatg cgagttgttt caatcaagtt
    12721 agccccagct tctgcttcaa tggtatagcc atcaacagaa acgttattga gcttgtcaca
    12781 caagatgaca aatccacgaa tcccaccatc acgaacgatg atattgcttg cattgccaag
    12841 aaccatccaa gggatatttt cttggttggc aaatttcaca acgcgagcca actcaaaacg
    12901 atttcgtgga aagaccaaat aatcagcctc tccacctact tttgtataac tatagctatg
    12961 caagggttcc tgaaaacgga tatcaattcc ttctaagatt tcaagcattt tttctcttac
    13021 agacatgtca ctcttccttt tacaaaattc attccattat accattttta gagacatttg
    13081 acgaccataa aaataccttg tttggatttt gcataagaaa aagaggttcc cctcttttta
    13141 tgatttttta caaaagattt ccttggttcc ataggcgacc agaacgagct ccagtgctag
    13201 aatcacttca accaagactg gatttgtcaa ccagcctact tggaaaagag atggtgccag
    13261 atcaaagaag gcatgcaagc cataggctgt taggagataa atccatttct tctggcgaac
    13321 agcttgataa acccaaactg tcaaaagtaa ttggaaacca agcgccaaga ttcgctcaaa
    13381 accaagcaaa taaatctgcc agaccgaaag tgactgaatg gtttttaaca tattttcaga
    13441 cagtaattgc ataacctgtg gattctgagt ttgaactgcc gaaagaacaa tgtaaagatt
    13501 gagtaaacta gtaaggccta gaaaaatcaa ctccaagcca ccatgcccca atccataggc
    13561 caaggcgtct gccttttcca aacttctctt tttctccaac catttgaaga aaacaagacg
    13621 agccgtttcc tcaaaaaatg ctaccatggc taggccatag ataatataga taagcggatg
    13681 aacttacaag agggcaatac taccgtcttt ttgaggatgc aaaatcaaga tatgcaccag
    13741 tttttccaaa atctgcgaag agacaaagaa agcgactgca cccaagtcca agacagctag
    13801 attaatctgg tatttctttt tggcaaacca aatgcttcct atcagaaaag ctagcaacag
    13861 caacatggta ataatgatat gaatggtcat tttcttctcc tattctgcct tttcaatatc
    13921 ttttttcatc tcgtcaacat tgaacttagc aaacaagtat tgacggtctt ggactgggaa
    13981 acgttggtcc aactggtcaa ttgctcccac ctcgataatg ccttccttga tgacaaaatc
    14041 catgacatgt ccaccgaagg tcaaatcatc tgatatgaag tgcagatggt agcctgccac
    14101 actgacccca tggaaaatct caggcgtcca gaaaccaaca atagtcccca caacattgtc
    14161 acgactatat tccggttgat gggttgcgac atcagcaaac ttggtatcgg gtgttgactt
    14221 aggaatcata cgcacatgca tatgtgaaaa ttccccccga atcttgatag agcggaaaag
    14281 attttcccca tcataataag actcaattcg ttctttcaat tccttgtctg tcatctcaaa
    14341 gcgctggcgg aaaatgacct ctgcctgatg cggtaccact gcagcgtaag gaataagggc
    14401 atctggtgac acttccacaa tttctggctg gtctcctgac cctttggcct gataagcctt
    14461 gccatccaag acaatcaatt ccccatcaat ggaatccaag gttcccaaac caaggtcacc
    14521 atgttctagc aattctccta ctgtcatagt accaccataa aggccagcca tcaaggctcc
    14581 aagggtattg tattgaaata atttcactgg ttcctgcacg ttcttatcca ttcactttct
    14641 tgtctgttat tctataaatc ttactcctaa gtataccaca tttgccccta gatgtgaacg
    14701 agagaaacgc tctagacatt gccaagaagg aaaaaaaagg gtacaatgta acaaaatcaa
    14761 gggaggtctg gaatgaagaa acaaagcaag tacaaagagg tcgtttccta tctgaaaaat
    14821 ggtatcgagt ctgaacgatt tccgacgggt agtcgcctgc cttctatccg tcaactgagc
    14881 cttgactttc actgcagcaa ggacaccatt caacgagccc tgctggaatt acggcacgaa
    14941 caatacctct atgccaagcc ccagagcggc tactatgtcc tagaacaagg gcaacatcaa
    15001 gacctagaaa tcgaggttac cgacgaacat gccagtgcct atgacgattt ccgactctgt
    15061 gtcaatgaaa ccttgattgg acgagaaaac tacctcttca actactatga caatcaagaa
    15121 ggattagaag acctaagaca gtccattcac aaactcctat ttgagcaagc tctctactgc
    15181 aaggctaacc aactagtact gacttctgga acccaacaag ccttatttat cctctctcaa
    15241 atatcctttc ctagacaagc caaggaaatc ttggtggaac agccaaccta ccatcggatg
    15301 aatcgcctct tgattgcaca ggggctggac tatcaaacga ttgaacgagg cattgatggg
    15361 attgacttgg aggagctgga aggccacttc aaaacaggaa aaattaagtt tttctacacc
    15421 attcctcgat ttcactatcc cctaggccat tcctattctg agcaggacaa acgagctatt
    15481 cttgacttag cagccaaata tagtgtttat atcgtcgaag acgactatct gggggatttg
    15541 gactctaaaa agggccagac cttccactat ctagatacag aggaacgcgt catttatatc
    15601 aaatccttct caaccagcct ctttccagcc ttgcggataa cagcactcat tcttccaaat
    15661 actatcaaag aagccttcgt ggcctacaaa aatatcctag actacgacag caacctcatc
    15721 atgcaaaagg ccctgtcact ctatattgac agtcaattgt ttgaaaaaaa tcgtttggct
    15781 cgcttgacca atcatgaatc ttaccaaaaa caaatcgagg aaaggataac taaaacacct
    15841 tgtccccttc ctcattatcc cctacacgat ggtttattgc tagacctgag acagtatcct
    15901 aaaatcgcca gtctcaaaca cagtcaactg ggcttggact tctttgaaga ggcctattta
    15961 agcacctgtc cttatcaatt tgccaaggtg tccctagaca atctggaaaa tgttttaaac
    16021 tatttaaaag cagaattgga atgacatcca actctgcttt ttcttattct tcaacttcag
    16081 ttaaacttgc tgctttttca agatagcttt ggtaagttcc ttcatcctta agtttttgga
    16141 tgaccttgtc taccacttct ttcaaatcat cactattttt tctaagagca acggcattgg
    16201 cgtcgccgtc cttcatcttc aagctgacag ttgcgacagc taagccagcg tttttagcag
    16261 cataactaag tgcaacaggc tcatccatat gaacagcatc tatttttcca gcctgcaatt
    16321 cattgactgc ttcacccata ttagttaggg aagttaattg agcttttggc aattgtgcct
    16381 tgaccattga ttctggaaca gtcccttttt gggctgcaat attagcactt tctaggctag
    16441 ttaaatcctt gtatttttcc acatcagcct tacgaaccaa gaaactaatc ttgttttcat
    16501 agtatgggat tgaaaaatca aagacttctt ttctctcgtc agtagcacta attcctgcaa
    16561 ctgctaggtc agccttacca gtttgaagac tggtcaaaac attgtcaaaa ctcatgctta
    16621 agatttccaa cttaacccca agttcatcag cgatagcctg agccatgtcg atgtctgcac
    16681 cgactacctg gttctttcca tcaaccaatg attgaaattc aaagggtgca tagtcaggac
    16741 tggttgccac aactaatttc cctttttgtt tgatagcatc cacagcagac tgagaaccat
    16801 tagaacctga ctggcaagct actaagaaga aacttgcaag aaaattacat aaaacaaata
    16861 tccatttttt tgatttcata aataaacaac ctctctgtta attttgtata attataacga
    16921 tatccaagtt acttgtcaag tgttttttaa atttttatct caaaaatatt ttttcgttca
    16981 aaaaaaggag ccatcagttg atttcaagct cctttttata cagaattaaa ctattttata
    17041 gttcgacaat cttacctgtt tcaaagtaga caacccattc acagatattt ttagcatagt
    17101 caccgatacg ctccaagtag gaaataactt ggaaataatc acgacccgta acaatggctt
    17161 ctggattttt cttaatctct tcagtcgcaa ggtcacggat agtttcaaaa tagtggttaa
    17221 tttgctcatc catggaggcc acccggtatg cgtcgtcaac agaaccatta agataaagat
    17281 caagtgctgc ttcaacaacg cttttaactt cacgtcccat ttttttaatt tcttcctcta
    17341 cagctggaat gcgctcttcc cccttcatac ggatggttgc ctgggcaatg gctacagcgt
    17401 gatcccccat acgctccaca tctgatacag ccttaaggac agtcaagact gtacgcaaat
    17461 cttgagagac tggttgttgg agtgcgatca tttcaaatga tttcttttcc agtttcactt
    17521 cgtattcatt tacttctgca tcatcttcga tgacctcttt tgccaggtca cggtcatgcg
    17581 tgacaaaagc acgtaccgta cgattgattt gtgagagcac ttcttgtccc atagcgtaga
    17641 actggttatg taatttctct aaatcttctt caaattgaga tcgtaacatc tttcatctcc
    17701 ttatccaaat tttcctgtaa tatagtcttc cgtttccttg tgttggggat caaggaacat
    17761 ctgcttggta tcattaaatt caatcaaatc tccatctagg aaaaatcctg tcttatcaga
    17821 gatacgtgaa gcttgctgca tggaacgggt taccagaagc atggtgtact tgtcttttag
    17881 accatacaag gtttcctcaa ttttaccagc tgaaatcgga tccaaagccg aagttggctc
    17941 atccaagagg atgattttag gactagttgc caagacacgg gccacgcaga cacgctgctg
    18001 ttgaccacct gacaatccaa tagctgaatc atatagacga tccttgacct catcccagat
    18061 agaggcacct tgcaaggctt tttctacggc ttcatccaga acctgcttat ccttaattcc
    18121 attgatacga agcccgtaga caacattctc atagatagtc atagggaaag gattaggttg
    18181 ttggaaaacc attccgattt ccttacgtaa ttcaaccgta tctgtacgcg gactgtagat
    18241 gttgtggcca ttgtacacca cggatccagt tgtggtcacc tctggattga gatctcccat
    18301 gcggttgaga gacttgagga gggttgactt ccctgatcca gatggaccaa tcaaggctgt
    18361 aatttcctta ggttggaaag atagggaaac actattcaaa gccttctttt tattataata
    18421 aacggacagg tctgatacct gtaaaatcgc atctgtcata cggtttcctt tctaaccaaa
    18481 gtgaccagat acatagtcat tggtggactg tagcttggca ttttggaaaa tagttgcagt
    18541 cttgtcatac tcaatcaaat cacccaagta aaagaagcct gtatagtcac ttgcacgagc
    18601 agcctgctgc atattatgcg ttacaatgat gatggtaaag tttttcttga gctcaaacat
    18661 ggtctcttct agttgcatgg tcgcaatcgg atccaaggct gaggctggct catccattaa
    18721 gaggatatct ggcttaacag agatggcacg agcgatacag agacgttgtt gctgaccacc
    18781 tgataaggtc aaggctgact tgtggagatc gtctttaacc tgatcccaga gggcagcctg
    18841 acgaagggag gtttctacga tttcatctag gacttgctta tccttaactc cagcacgttc
    18901 atgcgcaaag gtaatattac ggtaaattga cttagcaaat ggattggggc gttgaaaaac
    18961 cattccaatg tgtttacgca tttcataaac gttgatttct ggacggttga catcaattcc
    19021 acgatagaga atctgcccag ttactttagc aatatcaata gtatcattca tgcgattgag
    19081 actgcgtaag taggtagatt tccccgaccc cgacggacca atcaaagctg taattttatt
    19141 tctttcaaat tgcatatcaa tccccttaat ggattcattt ttaccatagt aaacatggac
    19201 atccttagta gaaagggcta ctttttcttc aggaaaggta aggatatgct tctcatccca
    19261 gttatatgtt gacatggctt ctcctttagg cagcggttaa tttcttgtgt agatagcttc
    19321 cgaacttacg agctccaaag ttaaaaatca ggataaagat caggagcaca gcggcagaac
    19381 ctgctgatac aatggttcca tctggaatag tgccttcact attgactttc cagatatgga
    19441 cagccaaggt ttctgcttga cggaagatag agatggggct agtcacactg aggatattcc
    19501 agttagacca gtcaagagct ggcgccgatt gccctgctgt atagatcaga gctgcagctt
    19561 cgccaaagat acgaccagat gccaagacga cacccgttac aatacctgga agcgcttctg
    19621 gaataacaac atgaaccact gtctcccagc gagaaatccc aagagccaga ccagcctcac
    19681 gttgggtatg gtgaacgtgt ttcaaactat cctctacatt acgcgtcatc tgaggcaaat
    19741 taaagactgt caaggccaag gcacctgaaa tgattgaaaa tccatactca aactggacta
    19801 caaagatcaa gtaaccaaag agacccacca ccactgatgg taaagaggac aagatttcaa
    19861 tacaagtccg cacaaagttg gtaacaggac cttttttagc atattcagcc aagtaaatcc
    19921 cagctcccat agaaagaggt acagaaataa tcaaggtaat gaccaatagg aaaaaggaat
    19981 tgtaaagctg aatgccaatc ccaccacctg cttgaaaagc agaagacctt ccagtcaaga
    20041 aagaccaaga gatatggggc aagccccgaa ccaagatata gagaatcaag gaagccaaga
    20101 ttgtcacaat gatgctagca atcgtataga ggacagctgt tgcaagttta tctaatttct
    20161 tagcgcgcat aatttttctt tcctctttct ttcgtaatca atttaatcac actgttaaaa
    20221 actaaactca tcaagagcag taccaaggcc agtgaccaga gaacattatt atttacagtt
    20281 cccatgacag tgttcccaat tcccatagtt aatatagaag ttaaagttgc agctggtgtg
    20341 gtcaaggaag ttgggataac agctgagttt ccgacaacca tctggatagc taaagcctca
    20401 ccaaaggcac gcgccatccc aaagaccact gcagtgaaaa taccagaacg ggccgccttc
    20461 aagatcacac gccagatagt ctgccagcga gtggctccca tagcgaaact tgcctcacga
    20521 taataacgag gaaccgcacg caagctatcc gttgtcataa aggttacggt cggcaaaatc
    20581 atgacaaaga ggacggaaat ccctgacaaa atcccaaaac cagtcccacc aaagacactg
    20641 cgaacaaagg gaacgacgac ttgcaagcca ataaatccgt acactactga aggaatccca
    20701 accaggagtt caatagctgg ttgcaaaatc ttcgcccctt ttggtgatac ttcggtcata
    20761 aaaactgctg caccaatagc aaagggtgtt gcgataaggg ctgagagaat ggtaacgata
    20821 aaggaaccca aaatcatagg aagggcacca aattctttac tagaaggatt ccaagttcct
    20881 cccaaaagaa agtcaaagat attcacacca ttgacaaaga aggtcgacaa gcctttttgc
    20941 gctacgaaaa ccaaaatcat ggccacaagg atgactatca aagaaagaca ggcaaaggtc
    21001 aaaccttttc ctaatttctc cagacgagaa ttctttgatg gaagcaacat tttcttagct
    21061 aattcttctt gattcattat tgtctccctt ccaacactgt cacagttccg gcagcatctt
    21121 tttcaacctt catttcctta atcggaatat acttcaatcc tttgacaatc ccttcttggg
    21181 tctcatccga gagaacaaaa ttgagaaatt ctgcagccaa ctcattgggc tgccccaatg
    21241 tatacatatg ctcataagac cacaagggcc aattattgct acttatattt tctggactta
    21301 agtcatagcc attcaacttc atgcttttga ccgaatcatc tatataggta agagataaat
    21361 aagagatagc tcctggactt tttgatacga ttgattttac cgctccattt gaatcctgct
    21421 cctgactttg catggcagac tgaccttcca taatgacagt atcaaaggta gcacgagagc
    21481 cagagccggc tgcccgattg ataacagaga tgggtaagtc cttaccacca acctctttcc
    21541 aattggttac ctcacctatg aagatttgac gaagttgctc tgtcgttagg ttatcaacat
    21601 caacctcctt attgacaatc agagccaagc cagctaccgc gaccttgtgg tcaacaagag
    21661 cagaagcatc aattccgtct ttttcctcag caaatacatc tgagtttcct atatcaactg
    21721 ccccagactg aacctgggac aagcctgtac cagaacctcc cccttggaca ttgaccgttt
    21781 ttccaacatg gatcgtgcca aattcatctg ccgctacttc aaccaagggt tgcaaggcag
    21841 ttgagccaac agccgttatg gattctccac gatcaatcca gctagcacag cctactaaac
    21901 aagccgtcag ccaaaaagcg ataagagaca gagcaagctt ttttcttttt ttcactgttt
    21961 ttctcctcga aaataattat gaatactgtg aattttttaa gtagttcttt atgagttgac
    22021 gcatgaattc ttaccaaatt tctgcgcaat tgattattta tataatatag gctatattac
    22081 tctttcctaa cctccttttt tcatatgtgg ataaaatctc ttgtctatcc cttcccccat
    22141 tgtcacccat tatagtcatt tcgtgtctct ttttcccctt tttaatgcaa gggaaattac
    22201 tctccttaga tgataatcca aaagctagaa aggtatctca aacctctcta ctctcccaga
    22261 ctagtttaca actaaaagga aaagattcta ttttatgaga aatctagttt acaagcggta
    22321 agaacgctaa taactaaact tcttgtactc tttgaaaatc tcttcaaagc agtgttttga
    22381 gctatctatg gctagcttcc tagtttgctc tttgattttc attgagtagt aaaactacat
    22441 gtaatggcaa tcaagatatc aagaatcatc ctactaaaaa aatccatact ttcactataa
    22501 catagaataa gatatttgac tagcattttc atttgaatct gaggcctttt ggaaaataat
    22561 ttttcaaaac atttccagta acctttgcaa agcccaagcc attgccttta accaaaactt
    22621 ggtaccaacc atttggcaga ctttctgcca gctgaacgat ttctccagcc gcatacttga
    22681 caaacgcttc ttggccaatt tcaaccgact gttcgacctg actcgatttc aaggctaaac
    22741 caagagcgaa actgggctca aagcgtttct tcttaaaagt acccagatgc agtccattgc
    22801 gagcaatctt gagcttccct aaatctggca aaagttctgg caagagataa agctggtctc
    22861 caaaagtctg caagataccc ggtagattga ccttcaaatg gttttgggca aattcctgcc
    22921 acaaggcaac ttgttcacgg ctgaggttac tcttacttgc cttaaattta ggagctggat
    22981 tgttaccctt aaactgtaga tgggcaacaa actgaccctc tcccttaaac tgatgagggt
    23041 acatccgagc cgtttctggc aggtcaatac cagctaccat tccattgata tgctctactg
    23101 gcaacaagtc aaaatcatac tcttccagca accaattgac aatctcttcg ttttcctcgg
    23161 gtgcccaggt acaggtcgaa taaaccagac gaccaccttc agctaacatg gtcactgcat
    23221 cctccagaat ttctctttgc aagctagcac attgactcgg ataatgtaag ctccaatagt
    23281 ccatagcatc aggttgctta cgaaacattc cttcaccaga gcaaggggca tcaagaacga
    23341 ttaagtcaaa atagccttta aagaccttga ccaagcggtc ggcagattca ttggtcacca
    23401 cgacatttgt cgctccaaaa cgctccatgt tttcaaccaa aatcttagcc cgtttgcttg
    23461 aaatttcatt ggaaacaagt agcccctccc ctgctagata ggctgccagt tgagttgatt
    23521 tgccccccgg tgcagcagcc aagtccaaga ccttcatacc aggactgggt tgggctactt
    23581 gagccaccat ttgagcagca ggttcttgcg aataaactaa acctgtagca tgctcaggcg
    23641 atttccctga aaccttccca tagtggcccc aaggggtttg agtaatggca tcagaaaagg
    23701 aaagttgctc ttcttttaag ggattgaccc gaaaggccga aaccgcttcc tcctcaaaag
    23761 aggcaagaaa atctcttgcc tcatctccta gtatttcttt atatttttca acaaatcctt
    23821 ctggaaattt catttaagtt cttttccttt cgtaaatata ggactgaatt tcctcctgca
    23881 tctcaagagg caccatcatg accggctgtc tggtttgaaa atcaggagct tcaccaaaaa
    23941 gggtcacaac ccgatagccc agactttccc ctaaaatact agctgcggca taatcccatg
    24001 gttgcagata ggtgagatag gtcaacaaat gccctgacaa aatcttggca aaactaatgg
    24061 ccgcacttcc atagatacga acaccaagaa ccgctcggct caaatcagcc agcccccatt
    24121 cattggtttc cagcatacca ctattccctg caatgagaaa atctccaagt ggtttagttt
    24181 taaaaggagc taggggccta tcatttagac aaactggaaa ttccccacca ccgtggtaac
    24241 aatccccttt gaccacatca taaatcagac caaactgtcc ctgaccattt tcaaaataag
    24301 ccatcataac agcaaaatct tcctgctggg ctacaaaatt attggtacca tcaatgggat
    24361 caatgaccca aaccttgccc tcttgaaccg aggctcgcag acaaccttct tcagcacaaa
    24421 tcttatcctc aggataacgg gacaaaatct caccaaccaa gagttcctga acttctttat
    24481 ccagtctggt caccaaatct gttggagagg acttggtttc aacacgcaag tcttcctgca
    24541 tatggtcaag aatgtactga cctgctttct taacaagctc tttagcaaat tcaaatttac
    24601 tttccaagag aaatctttcc ttcccctttt tctttggcag cctgaactgc tcggtaaagt
    24661 gaatagccac taaccgtttc aaattctcgt cccaaacgtt tctcttcgct cttgcttggc
    24721 acgaccgctt tgaatccctt ataggagtcc agtaactttt tagcctctac tttgccttca
    24781 taggcagctt caacatcatt aaaaaaagaa agcactgaag caagttcttc agtgctccac
    24841 gacaaatcta gtgggtaact atactgtttg ttcattaact aataccagct ctcattcttg
    24901 cttcttttag ttcttgctta cgataactac gagggagaaa agcacgaatc tcatcttcat
    24961 taaaaccgat ttgcatacgc ttggcatcaa taataattgg acgacgcaaa agactaggat
    25021 actgctcaat caaatgaagc aattccgata ccgaaatact ctctacatca atattcaatt
    25081 tttgaaaaat ttttgaacga gttgaaatga tgtcatcagt accattttcg gtcaaggaaa
    25141 ggatgtgttg caattctttt cttgttaaag gactggtcat aatattgtgt tccacaaagg
    25201 gaaccttatg tttttctaac caggccttag ccttacgaca tgatgtacag ctcggtgata
    25261 gaaatagtgt aatcatgctt ttctcttctt atctatactt tgctacttct attatacaaa
    25321 aaaataaagc gcttgactag ggatttttag aaaaaaagcc tattttttca agaaaaatag
    25381 gctttttgcg aacgattgac acaattggat ttggttaatt cactcttaac gatggtttta
    25441 aacgatatat atttttatat atgtaaatta aaaacatctt tcctttcact tcctacgact
    25501 tttcagatac agatagccaa agaagttttc atagagggca aaaaagagga ggaaggcatg
    25561 aagaaagaag gtctctggca aaatcataat aacaggatcc ttggctggat caaaaagcca
    25621 ggtatcatct cccacaaaga gaatttgatg gaaaagagta aagaattggt caaaaccaat
    25681 caaaactccc ccaagtccaa tcatcacagg taagactact agagccagga gactttttcg
    25741 ataaagagac aaaaagtcct ttttcacaat cctattgaca aagacataga aacttggcag
    25801 tgtcactaga gctactagct gaaccaaatg aaagagattc ttgaccactg cgaaatggtg
    25861 cagaccagct gctgacgaac gaaaatcagg catctgtaag acctgactaa aaggattggt
    25921 cagataattc atcaagatat gaaaattgta ttgaatggtt tctggtttta gatagactcg
    25981 attcgttaag tttagccact gaatctccat aggatagaaa atccaagcca gataaatggt
    26041 cagaaggatt gagagggaga ggagaaagag catagagccc caaaaggtca atttagtttt
    26101 catcaaaatc ccactccgca aggctagaaa ccacatgtgt cggtgcgatt ggcaggccag
    26161 ctacttcttc tgccttagta aaacctgtcg tcaccaagag cgttggaatg ccattgtcaa
    26221 tcccagcccg gatatcagtc aaataattgt ccccaaccat gattaactct tcacgttcca
    26281 aacctaagtg ctcaaccgcc ttgtccataa tgatggcatt gggttttccg atataaaccg
    26341 gcttcactcg tgtcgctact tcaagcagcg taatcaggga gccagcacct ggcaaaagac
    26401 cgcgttccgt cgggatgttg aggtcaggat tggttccgat aaaatgggca cccttttgaa
    26461 tagcaagagt tgctgtggca aatttttcat agtcgacttg ccaatccaga ccaactacca
    26521 cgtaggcagg gttttccttg tcttccacat aaccagccgc cttgatggct tccttgagtc
    26581 ctgcttctcc gacgacatag acggtctttt caagccccaa atcattcata tagtcgatgg
    26641 ttgccaaagt cgctgtgtag acagtcgata ggggcgtatc gatattaaaa ttctgagcca
    26701 acatctcctt aacactctct ggagtgcgag ttgtattgtt ggttacaaag agatagggaa
    26761 tgccccgctt ttgcaattca tgaacaaaag tctctccagc agggattcgg tctttcccct
    26821 tataaatggt tccgtctaaa tcaattaaat agcctttata tttcatctat ttctccctaa
    26881 gcctttttta tttcttgcca agtaatgatt gcttgggcat tgataacccc atcacttgta
    26941 atttcatgct tgctttccag tccagtccgt tcaacaaccg atgtaatcac tccacctggt
    27001 cgaacttcct tgacatactt gaggttgatt ttcttgggaa tatagtgggt caaaaaatcc
    27061 gctcccatga cctcaaaaat ccagtccaag tatttactgt tattgacatg accattcata
    27121 tccaagtcgt aaaaacgaac atggtaatcc ttgctgatcg gttcttccaa ggactcatac
    27181 ttcggtccac ggataagttt tttatcaaaa tcagactggt aaggagccac aatctcaggt
    27241 tcaacagcat ggacttttcg actgtcgcgg tccatgagaa caaaggtcgc catcatatgg
    27301 atgagctcct gccccgcttc attataaata gtaaagcgac ggtagcaaaa aagtcgattg
    27361 tagctcaagg cttccgtttc gatggtaatt tcttccgcaa aacgaggcaa acgaaccacc
    27421 tcaatatcat attctgcgat aatccagacc agattatagt cttccaaaat ggccttatca
    27481 ctaactccca gttcaatcga ctgcatccct gaaacttgca gtgacagcaa aatcacatct
    27541 ggaagtttga tatgaccgtt catatcagcc atatcaaaag gaattttcat tttcatttga
    27601 taagttaagc ccatgatcct actccaaaat aaatcgttct gctacagtat ctcccaaaaa
    27661 gagacctctc tttgtcatgc gaacgtggtc accctcaatc tgcatgaggc cttgttgaac
    27721 caaatctctg acaatttctc cataaagtcc agcaaaagac tgtccaaatt tttcctcaaa
    27781 tcgcgccatg gaaaccccgg atttcttgcg gagtcccaag aacatttctt cttccatttg
    27841 ctccttttga ctcaggtgat cttctgtaat acaagcattg ccttcctcaa ccgcactgag
    27901 ataatgacga atgggaccat gatttttata acgtactcca ttgacataac cagatgcccc
    27961 tgcaccaata ccatagtatt cagcattgtc ccagtacatg agattatgac gactttcaaa
    28021 gccgggtttg gagaaattag aaatctcata atgctcaaaa cccgctcgct ccagctctgc
    28081 aatgatgtac tcaaacatct ccgcttctag ttcctcctta ggcagaggca atttcccacg
    28141 tcgcatccgg ttcataaaga ccgtatggtt ttctaaaatc aaactataca aactcatgtg
    28201 gggaatatcc agtccaatgg ctttagccac attttccttt acttgctcca tggtctgacc
    28261 aggcagagca taaatcaaat caatggagat gttgtcaaaa ccagccagtt tcagacgatc
    28321 gatattttca taaatatcct tctccaaatg actgcgccca atctttttca acatcttatc
    28381 atcaaaggtc tggacaccta gcgaaacacg attgacagcc gaatttttca aaacagctat
    28441 cttatccgca tccaaatcgc ctggattggc ttcaatggtc aactcttcca agacagacaa
    28501 gtccaagttt ttagtcaagc cattcagtaa cacctccagt tgcggagccg acagggctgt
    28561 cggtgttcca ccaccgatat aaagggttga caacttttca atatcataag aacgaaactc
    28621 ttccagcaga tgctctaaat agctgtcgac tggctgattt ttgatgaaga cctttgaaaa
    28681 atcacaataa taacaaatct gggtacaaaa tgggatgtgc acataggctg acgttggttt
    28741 tttctgcata gtaattatta taccacaaag actagattcc agataaaaat caccatcccc
    28801 agatacatag tccgtccgga gatggtgatg gtttattctt ctgttatatc aatcacaatc
    28861 tcttctgagt catcaagagc ttcggctttt tcttgccatt gttccttgag attatttaat
    28921 tgattttttg atgcttctgt cgcttgaaaa gcataggatt tagcttgagc aagtatactg
    28981 tccacagtga tttcacctga ctcaacctgt tcttttgttt tcagaacaaa atctgtagcc
    29041 tgctccttaa cttctgtcag tttttcacag acttgctcct tggcatactc cggatcttct
    29101 ctcaaatcat ctagaaaatc ttgagcctga ctgcaaactt gtttgccctt atcacttgtt
    29161 aaaaacaagg caagagctgc acctgaaacc gttcctaaaa ggattgagga taatttaccc
    29221 ataaggattc tcctttttta ttttttgaaa aatttacttg caagacgaag agctgacaga
    29281 cttgcaccag tcttgagtgt ttttgaacca gctgatgaag ctttcttgct caagacacgc
    29341 gcatggtcat tgaggtctga aacagataga gataaatctg caacagcact gaagagtgga
    29401 tcaatcgtag ccaccttgac attgatatca tctgccaaga cattgacctt agccaacaac
    29461 tcattggtgt gatgcaaggt cacatccaca tctgaagtca aggttttaat cgtcttttct
    29521 gtttcatcga tgacacgacc aagcttttgt acagtaatga tcagatagac caaaaagaca
    29581 atcaaagcta gggcaacaag aatatatgca acttctaaca tttatttttc ctcctctgta
    29641 atatagtaag gggccttctt tcgattttga taaataacga tcattatacc gagaccgata
    29701 aggacaactg acagccattg ggacactcga aggctgaaga acatgagact atctgttcgc
    29761 ataccttcga tgaccatacg accgaaacca taccaaatca agtaaaaggc cgtgatatga
    29821 cctcgtctga gactcttcca tttccgtcta aaaatcagaa tcaaagcaaa gccaagcaga
    29881 ttccatagag actcataaag gaaagtcggt tgacggtagc tcccctcaat atacatctgg
    29941 tcacggataa agccaggtag ataatccaga ttatccactg ttgcaccata agcttcttgg
    30001 ttaaagaaat taccccaacg ccccaaactt tgagcaatca taacgctagg cgccgcaata
    30061 tctagaaaat cccaagtatt gatgagttta cggtcagcaa agatatagag cacaagagcc
    30121 ccagttatca aaccaccgta aatggccaaa ccaccattcc aaatggcaaa aatctctcct
    30181 aaattctgac tatagtaatc aaatcggaaa ataacatagt agagacgagc tcctaaaata
    30241 gccaagggaa aggctactaa gataaaatct aaaatatcgt ctggtatgat cttctttcta
    30301 ggtgcttctt tcatggtcaa ataaaccgca agaatcaagc ctgtcacaat acataaggca
    30361 taccaacgaa tggctagggg tcctagttga atagcaattg gatcaagcat tttgcacctc
    30421 atttcgagca atgagacttg tcagtcgttc gtcgaacaaa cgggtcgcat caaagcccat
    30481 ttccttggca cgataattca tggcagctgc ctcaatcaca acagagatat tacgacctgt
    30541 tttaactgga atacgaatac gaggaatggc tacgccagaa acttcaagtt cctctgcatt
    30601 gtttccaaga cgatcaaagg tcttatgtgt atcgtaattt tccaaataga cagcaagctg
    30661 aacctgtgaa gaatccttga cagcactcgc accgtagaga ctcataacat cgataatacc
    30721 aaccccacga atttcaatca agtgtttcaa aatttcagct ggttcacccc agagagtaat
    30781 ctcatccttg gcaaagatat cgacacggtc atcggctacc aaacggtgac cacgtttgac
    30841 aagctcaaga cctgtctcgc tcttaccaat tccactatct ccctgaatca agacgcccat
    30901 cccataaata tccatcaaga caccgtgcac actggtacgt tctgccaaac gagaatccag
    30961 atagctagat aactctccag ataaacgact ggtagctgca cggctggtta aaatagcaat
    31021 cttacattct ctagcagcct ttaacatctc ctctggaacc accaaaccac gggcaacaat
    31081 gactgctggt gtctcaggta gaaacatttt tttcaaaact tcataacggc tgttggaagg
    31141 catgctgatc agataagacc actccttcat ccccaaaagt tgaatccgct ctggtgtata
    31201 gtagtcaaaa tagcctgtca tttcaagacc aggtcgcgta atatccgctg tattgatttc
    31261 cttttcaagc aattctggtt caccatagac aatatctagt ctaagctttt caatcacttc
    31321 ttttactaaa accgacatca tttcctcctt caaatgagtt cttctctcta ttatatcaaa
    31381 ttgtaggagg aagtttcaga tttttgcagg ctttggagta tttatttaaa agaaaaagga
    31441 ctagatttct ctagcctttc atttcaatta gaatttttta cgtttacgag ctacttctga
    31501 tttacgttta cgttttacag aaggtttttc atagaattca cgtttgcgtg tttcttgaag
    31561 agtaccagct ttagtaaccg cacgtttgaa acggcgaagt gcgtcgtcaa gagattcatt
    31621 cttacgtact actgttttag acattttttt cactcccttc aagttcaata tctatttcat
    31681 tctacacgta aaaggaataa ttgtcaagca aaaatgcggt ttaattttga ttttttcttc
    31741 catttataca agagttgaaa gcgttcaata gaacattgct tttttatttt tcgagtaagc
    31801 taagcgcttc agcatctgcg atgatggtta catcagggtg attttggagg ctacttgcag
    31861 gtaggttctc agtcactggg ccagatactg ttccggcaat ggcttctgct ttcgactcac
    31921 cgtaagcaaa aagaataata gacttggcat ccaaaatgtt tttaatcccc attgaaatag
    31981 cttgggttgg gacgtcttca atcttggcaa agaagcgtgc attggcttca atagtagact
    32041 ggtcaagttc tactagatgc gtttgactgt caaatggagt accaggctca ttaaagccga
    32101 tatgcccatt gcgaccgatt cccaagattt ggaggtcaac tggatggtca gccaaaattt
    32161 ggttgtagcg ttcaacttca gcttcagcat tgtccttaac accacgaggc aagaaacttt
    32221 ctttaaatgg tttttggttg aacaagtttt cttgcatgaa gtaacgataa gactgtggat
    32281 tgtccccatc aaggcccaca tactcatcaa ggttgacact ggttagattt gaaaaatcaa
    32341 ggttactctc aacaatttcc ttgtaaaatt caagtgggct acttcctgtc gcaagtccta
    32401 gagtttgagc tccattagcc aatttttcct tcaaaatctc aaaagcaact tttccacctt
    32461 gaacttggtt ttcaacttta ataactttca tcttttcatc ctccatttct atctatattt
    32521 attatatggt atagaccaat ttttgtcaag tgaaaacgat ttaatttcta aaaaaagagc
    32581 gtccaaactt gaaacgtgtt ataatggata ggattagaac ttagaaagaa tgaacagata
    32641 tatgaataca gctgattttg atttccactt gccagaggaa ttaattgccc aaacgcccct
    32701 tgaaaaacgt gatgcctcca aactcctcat cgtcaaccgt gagacaggag aaatgcaaga
    32761 taaacacttc cactctatta ttaatatgct ggaacctggt gatgcccttg tcatgaacga
    32821 cacccgagtt ctccctgccc gcctctatgg tcaaaaagtg gagacaggag gtcatgtgga
    32881 acttctcctc cttaagaaca ctagtggaga cgagtgggaa gttctggcta aacctgccaa
    32941 acgcctcaag gtcggtactc gtatcagctt tggtgatggt cgcctcagcg ctgtcgttac
    33001 agaagaattg acccacgggg gacgcattgt ccgctttgaa taccaaagaa ttttcctaga
    33061 agtcttggaa agtctgggag aaatgcctct gccaccttat atccacgaaa aattagatga
    33121 ccgtgaacgt tatcaaaccg tctacgccaa ggaaagcggc tctgctgcag caccgactgc
    33181 tggtcttcac ttcaccaaag aactgctggc agaaatccaa gctaagggtg ttcatctagt
    33241 ctatctgact ctccatgtcg gactcggaac ctttagacct gtttctgtgg ataatctgga
    33301 cgaacacgaa atgcactcag agttctatca actttctgag gaagctgctg ccacccttcg
    33361 ctctgtcaaa aaaaatggtg gtcgtgtcat cgctgtcgga accacttcta tccgcacctt
    33421 ggaaactatt ggttccaagt ttgatgggca aatccaagca gattctggtt ggaccaatat
    33481 ctttatcaaa cctgggtatg agtggaaggt cgtggatgcc ttctcaacca acttccacct
    33541 gccaaaatca actctggtca tgttggtttc tgcctttgca ggccgtgaat tagtcttaga
    33601 tgcataccac catgccatcc aagaacacta ccgcttcttc agttttggtg acgccatgtt
    33661 tatttattga gaaagaattt ctctaaatct tctaatacca ataaatcgct aagatattat
    33721 ttcaaagaac atctacaatt gaaactctag ctagctgtag aagaggccta gtacattgaa
    33781 attaaaatgc ttccccctag cttcgaaaat attgccatag attgcgttga ctctccaaat
    33841 tgattcatct atattttatt tcagcttcct atactttctt cgctgtttgt aaatcaaaat
    33901 gcaagacaca tgagtagcac catatttgtt actcttatct gtcctctcaa gagactatta
    33961 tgagttattt cagaatcatt cactactttg accctgactc tccttagtct caaaatcaaa
    34021 gacttatact cttcaaaaat ctcttcaaac cgcgtcaacg tcaccttgga ttatatatgt
    34081 gactgacttt gtcagttcta tctacaacct caaagcagta ctttgagcaa cctgcgacta
    34141 gttttctagt ttgctctttg attttcattg agtattaaac aaaaagtgaa caaagctgaa
    34201 ttctaatgta cagaagacta ggcttgttca cttttttata gtcgctataa gatgacctta
    34261 tctatagctt tttatatata attatatatt cagacatact attatcaatt ttgtctcagg
    34321 gaggaatctg ttaacgcacc cattcaccat tatcattgac tctatagcca tctatacttg
    34381 tattgaccgc taactcaccc gatgcattta cataatacca tttaccacca acttggaacc
    34441 attgattaac tttcatagaa ccgttgctgt tgaggtagta ccatgaacca ttaacttgta
    34501 cccaacctgt tgccatggaa ccatcagtat tataaaaata ccacatacca ttttcttgtt
    34561 tccagcctgt tgttggagca actgctttag ctggttctac tgctacatct gttccttggt
    34621 tagatgtaac agatacagga tacgaaggaa tagatgattg ctcaggaaca acaacttttt
    34681 caggttctct cgtccctctc cttatacgtc tttttaccat ctctttagta atttgacgag
    34741 aagtagtttc ttcaattgtt ccatcacgtt catctacagc atagattgta gtaagagtaa
    34801 ttttaccaat ttctcctact tcttgacctt tatcaagagt tgggtcatcg agatattctg
    34861 tttcgattgg aatttcttgg acaagaactt ggggcttggt tcctttttta acaactcttg
    34921 tttgagagtc ttctttttga cttaaagtac tctcagttac ttgtccactc tttccatcta
    34981 catcataagt tatcgttgta actgttttcc cattctttcc tagagtaatc tcttgctcct
    35041 gtcctgcaga aaggtcattg tctgcttcat atttagtagc acatggaaca agaacttctt
    35101 caaccttgct tttagctgga actttgataa ctgtatccgt ggcttctttt ctatcaacag
    35161 taacctgttc ggtaacatga ccagtctctg gattaacatc gtaggtcctt gtcgtagtta
    35221 catagccatc ctctccatca attgtaacag gattttcact acggtctttt gtttcatctt
    35281 tttcataacg aattcgcgta cttgaaattt tcttggttac taccttaggt ttagtcgcta
    35341 cttttacaat aatatcccca ttgtcagcgt catcatactc tattccctct tctttatctc
    35401 tagtatcatc tctgacatat tgaatcccat cagcagcatg aacaaaactt gtattcagat
    35461 tcctcctaaa aataaagtta gcccgattac cgcagaacca aaaatctttc cgagtttacg
    35521 taatgcatag cgcttattgg tattagattt tgccattaca tcctacttct aaaagttact
    35581 acttctagta tagcatcttt tctatcaaac gttaaacagt atactttata tatcaaatat
    35641 acttagaatg atatattgat tattgaacta acgctttaac tatatcgtaa tcaatctcat
    35701 atataaagga ttgcagacat cttatctaaa tacatgctaa tatatttaga tacaaacatt
    35761 ccaacttgat aactttcact catctttcat cattccttat acaactatgc agtataaata
    35821 gaatagtttt ctcatcagaa tgagactatt ttaatattag atattttgat agaaaaaaca
    35881 tgaataaaat tggttgaatt taattcccta actcgataga ggattctatt ttaaatttaa
    35941 caacagctag gattacacta taaaaagtac attaccacct gttcggctgg agaatctagt
    36001 cgattagctc cctcttagtt acaagcttaa agcgattttt taactaatac taaaccagat
    36061 taaagaagga actagaacat ctgtcttgta ctaatcaata tgctatttta aagttgcaaa
    36121 taaacttgga atgctaatta ttatatttac aataaatagt tgacttcgat agaaacagaa
    36181 aatagaattc aacattcttc cctacttata ccataataaa taagatccgc aagatagcct
    36241 tttctctcta caccattaac aatggtttgt agataggaca ttccagcctt ttccatgaca
    36301 cgacctgaag ctgggttgag actggcataa cgtgctctga ccttttgaaa acctgcttga
    36361 gtaaaacaaa agtccaagat agctttcaaa gtctctgtca tcataccatt tccccagtaa
    36421 gccttgccta acacatagcc aatttcacag cttaaatcag cctcgtctat cttaacaatg
    36481 ctgatatctc ctatcacttg ctctgggttt tcttttagac aaatggccca tttataatag
    36541 ttgagattag tataggaagc aacccaattg caaatcgagt ttcgagtgat ttcgacatca
    36601 ggatggggat cccaggtaac ataggtcaga ttctcagcgg atgaagccca attttgaaac
    36661 atggcttctg catcactctc cacaaatctt cttaaaatca aacgttctgt ctgtaatatt
    36721 tgcgtaccga tagatttcat gatgctacct cacttcctta tttctatgct cgtagtaaaa
    36781 aggctcaact cagtaacagc tagaaaacga gtttgtcttc taatttcttg acgcagtcgc
    36841 tgcctggttt gaaatgcgct ctagcaatct ttttcaaacc tagtcatcgt tgcaggggta
    36901 agacgatgaa atcgaactct tcgagttacc gaatctgcct cattttctta tttcaagatg
    36961 agaggctgaa aacctccagt ggaggttttt cttgcttttt aatttcaggg caagaagcta
    37021 aaaaggtccc ccggaccttc ttcgctttct catttctagg ctcagggtaa aaacctccaa
    37081 tggaggtttt tactcccaaa agtcatcaaa tacggtgatg ggtaagtggc gtttgtgttg
    37141 gcctttgtgc caccagtttt caatggtcgc ttgagcttct gggctgattg ttttgccttc
    37201 taggtaatcg tcaatctctg cataggtgac tccaagtgcg acttcgtcag ctaggcctgg
    37261 tttgtcttct tctaggtctg ccgttgggat tttttcataa agggctgggt ctgcaccaag
    37321 ttcctgtaag agttgttttc cttgacgttt attgaggcgg taaagaggga gaatatccgc
    37381 accaccgtca ccaaacttgg taaaaaagcc tgtgatattt tccgcggcgt ggtctgttcc
    37441 aatgaccgct ccgctatggg aaccagcaag ggcatactga gcaatcatac ggcaacgtgc
    37501 cttgatattc cccttgttga agtctgaaac aggactacct gtcgcttcaa ctgcagctgt
    37561 catggcatca gctgattcct tgatattcac aaccaagctg acatctggct ggatgaaggc
    37621 tagggctttt tgagcatctg cttcatcagc ttgcactccg tatggcaggc ggacaacgat
    37681 aaatttgtag ctgtcgtctc ccgtttcagc tcgcagttct tccatagcta attgcgccaa
    37741 acgccctgcc aaggttgagt cttgtccccc agaaatccct agtacaaagg tttttaggaa
    37801 gggatgtttt ttcagatatc tttttaagaa atcaatagaa cgacggattt cttcctgggc
    37861 atcaatcact ggtttgacac ccagctcttg gataatcgtt tcttgcaaac tcattcttct
    37921 tctccttcac caagggcttc cttgcgcatc ttatcaatca agtccatctt atcttgccat
    37981 acatcacgcg ccaaatccac tggatagtgc tgcggattga gcacacgctt atactcatcc
    38041 cacaacttgt caaattcctt acgggcataa tcctgaatgt cagtcaaact aggcaagttg
    38101 taaactaata ttccttcttt gaagatatcc accaagagag gaacggcatc aaaattacga
    38161 accgtcttct tgatgtatgt ataggtcgga tggaacatct tgatttctgt catgtcgcta
    38221 atatccacac catcataagt gatatagtcg ccttctgact tgcctttttc acgactggta
    38281 atgcgccaca cctgcttctt acctggcgta gaaacttttt cagcattatt agacagctta
    38341 atcgtattgc gcatctgacc agtttcatct tcgattgcaa caatcttgta aactgcacca
    38401 agagctggct ggtcataagc tgtaatcagc ttggtaccca cgccccagac atcaatcttg
    38461 gccttttgca tcttgagatt gaggatagta ttttcgtcca aatcattaga agcataaatc
    38521 ttagcctctg taaatccagc ctcgtccagt tgctgacgga ctttcttaga aatgtaggca
    38581 atatccccag agtcaatccg cacacccata aagttaatct gatcacccag ctcacacgcc
    38641 acctgaatgg cagctggtac accgatgcga agggtgtcat aggtatccac aagaaagaca
    38701 caatttttgt gggtctcagc gtaagccttg aaagcttcat agtcattgcc ataaacctgt
    38761 accaaggcat gggcatgggt tcccaaaaca ggaatgtcaa agagcttacc cgcacgcacg
    38821 ttgctggttc cattggcccc accaatcacc gctgcgcgtg ttccccagat ggccgcatcc
    38881 atttcttgag cccgacgtgt cccaaactcc atcaagggtt catcttcgat aaccgaacga
    38941 atacgagctg ccttcgtcgc caccaaggtc tggtagttga cgatgttcaa aagagccgtt
    39001 tcgaccaact gacattgggc tagaggtcct tccacctgca caatcggttc attagcaaaa
    39061 accaaatccc cttcttgggc agaacgaacg gtcaactcca acttgaaatt gcgaaggtaa
    39121 tccaagaacg ccccatgata accaagcgac tccaaatagg ctatatcact atctgaaaaa
    39181 cgcaagtctt caagatagtt cacaattctt tccaaacctg caaaaaccgc atagccgttc
    39241 ttaaaaggct gttggcggaa atacacctca aagaccgcct tcttattgtg aatcccttgg
    39301 tcaaagtaaa cctgcatcat gttgatctgg tacaagtccg tgtgcaatgt caaactatca
    39361 tctggataca tacttttcct acttccttag ctagaaaccc atgaaaattt tcaagaactt
    39421 tcatgtattc caataaatta gtactattat atcacatttt agctggattg agaaaagagt
    39481 aacaagctat tctccactct ccaattcatc catatcttgt tcaaattttt tctgagccca
    39541 ttcgccatag ctcttaagac caagattgcc aataaagacc cacggaaggt aaatgacata
    39601 agtaatgacc caagcagaca ggtatttaaa attcaaagga ttgtgctgat aaatttctat
    39661 gttgaattga taattctgca acatcaaaag agccgtaata gccaaggtta ggaaaaaaca
    39721 acccaaaatc gtaaaatgaa aacgactata gtaggtcact cccagataac gggcacgatt
    39781 gaaaaagtaa aatgtcccta tgatgataac gattagcagc atattagaat taaaaaggct
    39841 tggtgctaat actgaaatga tataagatag gagcgacaaa gcgatgcaga tatagaaact
    39901 ttcagagccc gctttattga acagttgttc ttctctttcg tctagtaatt gataataata
    39961 aaatctattt ttcatcttct tcctcccaaa atagttggtc tagggttttc cctaaacatc
    40021 tgcaaatgga ctggcagagc gagagactgg gattgtattt ccccgcctct atcaaaccaa
    40081 tagtctggcg cgtcaccccg acagcatctg ctagttgacc ttgagttaaa tcaagctcta
    40141 cccgagctaa ttttaatttt aaatttttaa ccaccttcgt cctccttata attttaatat
    40201 tcatctactc ttaaaaaatt ccaaactaac acaagctgtc agctatttat tataacccca
    40261 ttaatttgca ctccagtatt atcttcagcc gaaaatcagt attttaggtt gtttgaaata
    40321 aacttcctag tttactcttt tatttttatt tagtattagc tttagtagga gcttttaaac
    40381 gagtttttat tgcttatatt tcttgtttag tttagttggt ttcatatcac tattatataa
    40441 tgcttttgaa aataagccta gtataagtca aaaacgtgtt gaatagtgaa agcaggagca
    40501 taccaagatg actgattttt ttactgtatt ttaggtatgc aaaataatac taaatgaaac
    40561 taaaatgaat acttcttgct tttcttgaga gtgaaaaagt acaataaaat gattgtagtg
    40621 attagcacaa gatactgact aatagacatc gtatttgaag tcacaaatac aggtaaagaa
    40681 taaaaaggaa gaagttcaat tgctttgata aacaaatcat tactagtatt catcatcatc
    40741 gtatttaata tattagggat aaagagtagt aaagctacta aaataccaaa taccaagcca
    40801 cttttcaatt tgtataaata gaaaatgtaa gataatagaa aataaaacag gactaacaaa
    40861 attgtattga ctacaatagc tactataaaa tctaatccta aatcacctgg aatacccaat
    40921 ttacttacta tgactagtaa cacaatgcca ttcaaagcat aaataatgga aactgagatg
    40981 gcatatagaa aattagacaa gacgtaaatc atccgattct tctgttgatt ataaaacaaa
    41041 cttaccgtat tgtgggaaaa atctctacta atgactcgat tagcatgtat aacagccatt
    41101 aacataccga gcatagcata aaagtttgaa atatgcttaa taccaagcga tgtcccttga
    41161 gtctttagaa taaagaatgt aaccaatatc ggcggtataa acgagataag caaaccgaga
    41221 tatattacac ctgatgaata taaatttctt atattttcct taagaaaatt aaatttattt
    41281 aatttcatga ttataaccct cctttatttt gaacgattta gataaatatc tttaagcgtc
    41341 tcttttttag ttttaaaatc aactacttta atagagtttt cgttaaaaaa tttaaaaagc
    41401 tcactacttt gaatattccc agacatagta attctcagtc cctcttcctg aacaatatcc
    41461 ccaaattctt gtttggtaat gaaaatgtct ctatctgtag ctgatgaaaa agctatctca
    41521 aacaagaaat tatgactatc ttttcctact ttttgaaatg tcaaaagccc gctctccaag
    41581 aaaagaaccc tctcacaaat ttcttcaata tcttctaatt tatgactcga tattaaaatt
    41641 cccacatttt catgtaaagc taaatttttt agaaccgcta aaactatttg tgatgattca
    41701 atatctaaac cattagtcgg ttcatctaaa atcaatatat caagttctgt aacgagggtt
    41761 aaaagcaaag ctaatttttg ttttgtaccc aaagaatagg tctttacttt tttattaata
    41821 gactgagtca aatctaactc ttggatcaaa cttctaaatc tttcttgatt gtagtcaaca
    41881 ccatataaat ttgacaaata ttttaaattc tctaaacctg ttttagataa aaataatttt
    41941 ggttcttcga ttaaataccc aacattatca ctgcttataa tattacctga agtcggttga
    42001 ttattctgaa caagaatttt catcaacgta ctcttaccaa ctccatttct ccctacttga
    42061 ccaacaattt cacccttgtt aagtgcaaaa tttatatctt tgagaataat tgaatgacca
    42121 taatgcttac ttacattttt tattcctcca ttaatattat tggttttctc tttgattctc
    42181 attaatttta aaaagttgcg cctcttttta acaatattat atcatatatc taacttaatg
    42241 caatatataa atgtcatttt gtgaaatttt attaacaaaa aactctatac aacaaaataa
    42301 tagagagttt tctgcttatt aatttttttc aaaatatcta agacatcgct tctttgttta
    42361 atttgatagg ctttgatacc taagctccga ctttatcact taaaaaataa aaaagacagc
    42421 taatctcttg cgcatcaggg gatttcgcca ttctttaatc tcgtttaagt gttgtatatg
    42481 gagctttgca taatttttta aaactaaaca actacattaa gctcgaactg tgacgctggt
    42541 tccatcttcc ttataaagat tgataagccc ctctttaaga gctcgaacca tgtctccagc
    42601 ttgaacaggt tgtgggactt taatagtcaa tagttccatt ggatttggag cgcggtcgat
    42661 tttatttcct ttggcatcat gcaaatcttc aatataggtt tcaaaatgac ggaaacctgg
    42721 accataaaac tcaacttggt ccccttcgtt aatgacgttc cgttgacgaa tggttgctgt
    42781 ttgtgtcgca tcatcataag aaaccacttc agcgacaaac ttgtactcag gaattttacg
    42841 acgagcacca aacaactgct cattttcaga tggtgtacca tagtaaaatc ctgtaaccag
    42901 ttcacgttgg gcaaccttcc acatctcgtc caccaagtct tgtttgatag cttcaaactt
    42961 ttcagaactt tcaagatagg catccacagc cgccttgtag cagttggtta ctgttgatac
    43021 gtagtgaata gacttcatac gtccttcgat ttttagactg tccacaccat tttcaatcat
    43081 atctggaatg tggtcaatca tagacatgtc aacggctgac attgaaaatt cttctggaat
    43141 ctcaccctgc aaactcttac gttctttccc aaatggcata tcgtaaaggt cgtatttcca
    43201 acggcatgac tgagaacatc caccacggtt ggcatcacgc atactctaga cggattgttt
    43261 tgacaattct aaccttttag actttgcata ataactgtta aacagtcgaa aattacccca
    43321 gttttaacaa gtagtcaaaa taccagataa aggaaaaaag tctttaaaat cttaaaaacg
    43381 catagtatca ggtattgaac aatcttgata ttatgcgttt tattgtggga agatttactt
    43441 cattttctct tggaattgag ttttctccta cttcaaaact agatgatttg ctatttaaaa
    43501 tagcgttcct tatgattttg gcaacctgga ttaaagcgag aaaaacaaaa ggggcaactt
    43561 aaactttctt tatattgctt atatgttagt agttttagac aaacaccaca taaaataggc
    43621 ttatcctgta tcaaagataa gggatacggc tcaaaagggt gattttctaa tgaatcatga
    43681 caccgataac aagcatagta ctttttacaa tcatagcatt gtaaagcaat aatatccaac
    43741 ttgctatggt aatgaatgca tcttgtttgc ttatccacta agaaaccctg tgcctctatc
    43801 atttcctttt cctttcttaa gctcgaactg tgacgctggt tccatcttcc ttataaaaat
    43861 tgatgagtcc ttcttttaat gcacgaacca tgtctcctga ttgaacgggt tgtgggactt
    43921 taatagtcaa tagttccatt ggatttggag cgcggtcgat tttattgcct ttggcatcat
    43981 gcaaatcttc aatataggtt tcaaaatgac ggaaacctgg accataaaac tcaacttggt
    44041 ccccttcgtt aatgacgttt cgttgacgaa tagttgctgt ttgtgccgca tcatcataag
    44101 aaaccacttc agcgacaaac ttgtactcag gaattttacg gcgagcacca aacaactgct
    44161 cattttcaga tggtataccg tagtagaaac ctgttgccaa ttcacgttgg gcaaccttcc
    44221 acatctcgtc caccaagtct tgtttgatag cttcaaactt ttcaggactt tcaagatagg
    44281 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
    44341 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaatg tggtcaatca
    44401 tagacatatc aacggctgac attgaaaatt cttctggaat ctcacccttc aaactcttac
    44461 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
    44521 caccacggtt ggcatcacgc atactcatgt ggtttgaaag agtacaacgt ccagagtatg
    44581 aaatacacat agctccatgg acaaaggctt caatttcaac atctgtacgt ttgcggattt
    44641 cagctaattc ttccattgaa acctcacgcg ctaaaacgac acgagtcaag cctagctctt
    44701 tccagaactc aagggtttca tagttagtgg cactggcttg ggtagaaagg tggatttcaa
    44761 ggcctggtgc ttcagtcgct gcaatcataa tcaaggctgg gtcagatacg ataactgctg
    44821 caatcccaat atcacgcagt ttacggaacc actcaccagc accagcttca tttccttcgt
    44881 gcataaccat attagccgct acatagacct tggcaccata cttggccgca aactgcacgc
    44941 cttcttccat ctgttcgaaa gtaaagtttc cggcacggct acgaagacca taggcctgac
    45001 caccgataaa gacagcatct gctccatact gaacagctac ctttagcttc tctaaagtcc
    45061 ctgcaggtga taaaacctca ggacgtttta atgtttttgt catgatttct cctatttgca
    45121 atataaaagt ttgacatttt tccttctcat tttatagtaa ataaaggata aaatcaagcc
    45181 tagacggatt gttttgacaa ttctaatctt ttagactttg cataataact gttaaacagt
    45241 cgaaaattac cccagtttta acaagtagtc aaaaagtcta gaaaagtaaa aaccagtatc
    45301 caaagatact gactcgtaaa aatacataaa ttagtcctta gatgactact cccactctgt
    45361 tgctcctata atggaaaagg attgatacag tctagaatat cgctttttta tttattattc
    45421 tgatataaaa ctgttagaat tgattttttg ttttataccc aaatatg
//
LOCUS       DAVHSL010000013        42012 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000013 DAVHSL010000000
VERSION     DAVHSL010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.013"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            752..1234
                     /locus_tag="VVR39_000714"
     CDS             752..1234
                     /locus_tag="VVR39_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEU6030244.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            1231..1827
                     /locus_tag="VVR39_000715"
     CDS             1231..1827
                     /locus_tag="VVR39_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6030245.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            1808..2299
                     /locus_tag="VVR39_000716"
     CDS             1808..2299
                     /locus_tag="VVR39_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030246.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            2679..4832
                     /locus_tag="VVR39_000717"
     CDS             2679..4832
                     /locus_tag="VVR39_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6030247.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLDGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            4845..6194
                     /locus_tag="VVR39_000718"
     CDS             4845..6194
                     /locus_tag="VVR39_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU6030248.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            6365..7072
                     /locus_tag="VVR39_000719"
     CDS             6365..7072
                     /locus_tag="VVR39_000719"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU6030249.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            7274..10999
                     /locus_tag="VVR39_000720"
     CDS             7274..10999
                     /locus_tag="VVR39_000720"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU6030250.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELKAVKNYLLNLVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            11092..12534
                     /locus_tag="VVR39_000721"
     CDS             11092..12534
                     /locus_tag="VVR39_000721"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU6030251.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            12571..13593
                     /locus_tag="VVR39_000722"
     CDS             12571..13593
                     /locus_tag="VVR39_000722"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU6030252.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGADPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            13590..14135
                     /gene="purN"
                     /locus_tag="VVR39_000723"
     CDS             13590..14135
                     /gene="purN"
                     /locus_tag="VVR39_000723"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU6030253.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            14219..14728
                     /locus_tag="VVR39_000724"
     CDS             14219..14728
                     /locus_tag="VVR39_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6030254.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            14753..16300
                     /gene="purH"
                     /locus_tag="VVR39_000725"
     CDS             14753..16300
                     /gene="purH"
                     /locus_tag="VVR39_000725"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU6030255.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            16422..17684
                     /gene="purD"
                     /locus_tag="VVR39_000726"
     CDS             16422..17684
                     /gene="purD"
                     /locus_tag="VVR39_000726"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU6030256.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            18087..18575
                     /gene="purE"
                     /locus_tag="VVR39_000727"
     CDS             18087..18575
                     /gene="purE"
                     /locus_tag="VVR39_000727"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU6030257.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            18562..19653
                     /gene="purK"
                     /locus_tag="VVR39_000728"
     CDS             18562..19653
                     /gene="purK"
                     /locus_tag="VVR39_000728"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU6030258.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGNEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            19663..19890
                     /locus_tag="VVR39_000729"
     CDS             19663..19890
                     /locus_tag="VVR39_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU6030259.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            19953..21251
                     /gene="purB"
                     /locus_tag="VVR39_000730"
     CDS             19953..21251
                     /gene="purB"
                     /locus_tag="VVR39_000730"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU6030260.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(21306..25268)
                     /gene="strH"
                     /locus_tag="VVR39_000731"
     CDS             complement(21306..25268)
                     /gene="strH"
                     /locus_tag="VVR39_000731"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6030261.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETEAPKTVETETPATDKVASLPKT
                     EEKPQEEVSSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDK
                     DKPAKKDEAKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDK
                     AKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNH
                     LTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTV
                     DLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNE
                     GYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGG
                     WGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVP
                     KTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNE
                     VPKDLNRYTAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEA
                     QKEEEAKREVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLR
                     FLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIG
                     LIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMD
                     FFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMA
                     FNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILG
                     QKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEI
                     FELMTAFADHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRN
                     KQAELDTLVANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKK
                     ENPNLPAGQENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPV
                     THKGDESGLAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFY
                     SVSTSADGKEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQ
                     PAPSTAPAEESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED
                     "
     gene            complement(25583..26299)
                     /locus_tag="VVR39_000732"
     CDS             complement(25583..26299)
                     /locus_tag="VVR39_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6030262.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            26647..28434
                     /locus_tag="VVR39_000733"
     CDS             26647..28434
                     /locus_tag="VVR39_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU6030263.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            28431..28907
                     /locus_tag="VVR39_000734"
     CDS             28431..28907
                     /locus_tag="VVR39_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6030264.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            28935..29840
                     /locus_tag="VVR39_000735"
     CDS             28935..29840
                     /locus_tag="VVR39_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6030265.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            29827..30642
                     /locus_tag="VVR39_000736"
     CDS             29827..30642
                     /locus_tag="VVR39_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6030266.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            30649..31053
                     /locus_tag="VVR39_000737"
     CDS             30649..31053
                     /locus_tag="VVR39_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030267.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            31306..32472
                     /locus_tag="VVR39_000738"
     CDS             31306..32472
                     /locus_tag="VVR39_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU6030268.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPVVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INEDTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            32588..33625
                     /locus_tag="VVR39_000739"
     CDS             32588..33625
                     /locus_tag="VVR39_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU6030269.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTYGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            33832..34686
                     /locus_tag="VVR39_000740"
     CDS             33832..34686
                     /locus_tag="VVR39_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6030270.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVES
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            34836..35055
                     /locus_tag="VVR39_000741"
                     /pseudo
     CDS             34836..35055
                     /locus_tag="VVR39_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(35185..35571)
                     /locus_tag="VVR39_000742"
     CDS             complement(35185..35571)
                     /locus_tag="VVR39_000742"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030271.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFKVVDGTDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYKSPHNKTHT
                     IKVFMYCPPKVRQKKSNFWGAVHFNT"
     gene            complement(35625..35908)
                     /locus_tag="VVR39_000743"
                     /pseudo
     CDS             complement(35625..35908)
                     /locus_tag="VVR39_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(35898..36059)
                     /locus_tag="VVR39_000744"
     CDS             complement(35898..36059)
                     /locus_tag="VVR39_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU6030272.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            36129..36893
                     /locus_tag="VVR39_000745"
     CDS             36129..36893
                     /locus_tag="VVR39_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU6030273.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(37133..37285)
                     /locus_tag="VVR39_000746"
     CDS             complement(37133..37285)
                     /locus_tag="VVR39_000746"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030274.1"
                     /translation="MRTKASIRKLVTGCSKHCFEVANRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            37503..38882
                     /locus_tag="VVR39_000747"
     CDS             37503..38882
                     /locus_tag="VVR39_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6030275.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            38896..39561
                     /locus_tag="VVR39_000748"
     CDS             38896..39561
                     /locus_tag="VVR39_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU6030276.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            39696..39854
                     /locus_tag="VVR39_000749"
     CDS             39696..39854
                     /locus_tag="VVR39_000749"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030277.1"
                     /translation="MKIKDQTRKLAVGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            39916..40455
                     /locus_tag="VVR39_000750"
     CDS             39916..40455
                     /locus_tag="VVR39_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6030278.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            40522..40932
                     /locus_tag="VVR39_000751"
     CDS             40522..40932
                     /locus_tag="VVR39_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6030279.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            41048..>42012
                     /gene="pavB"
                     /locus_tag="VVR39_000752"
     CDS             41048..>42012
                     /gene="pavB"
                     /locus_tag="VVR39_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU6030280.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLE"
BASE COUNT        11666 a         8005 c         9635 g        12706 t
ORIGIN      
        1 aaattatttc tttaattcta cctagtttgt tttcaattat aagtaaattg ttcttatttt
       61 tatctatagg actattgtct atagaacaag gacaagttgt aatttatgtc atactactca
      121 attattttat tttagtcatg gggatattag ataatcatgc gagtaatttc tattttaaaa
      181 gcagtcgaat gagtcaaaaa agatttcgta gcagtctatt tatattgctt cgtttttgtt
      241 ggttaaataa agggttaact ttttctttta ttttgattag tattcttctt tcctatctat
      301 tttggtatat gatgacgatg ttatcaattg atgacacaaa aataccaata ttatttcttt
      361 atacctcaat atatattaca ttaatggagg caataatagg gaatcataaa tcctcaattg
      421 gggtagatct agctttactt caattatctg ctcttaatca ttctaaaatg aatttctttt
      481 ttaagaatgc acaactaatg atgttgacgc atttaatctc tttcttacaa ttttcattgt
      541 tgttatgttt gattccggtg acaagttata gtaatgatat aaaaagtatt ttgttgaatt
      601 tgttattgat tccattcaat tattttatag cctatgtcta ttataagaaa gctctatttt
      661 taattaaagg tacagttagt ttattgagat ggagttttct ggttttatat tgttttctga
      721 taatatttgt aattttagta gggggcatta gatgagaaaa agtggttttc tgatttacta
      781 tgtgttattt tgtatagtct gttttttact aggtttactt ttaagcttta tattaaaaaa
      841 tgagactttt gctactatac ctccgaaact ggaattacaa tttacattga cagttttaca
      901 ggcaaattct acaaattttt tgctatatct attctgtttt ccgatttcgc ccttattgca
      961 actttttgat ttgctatctt taggaataca attgggtata tctggtcaga tgattggaat
     1021 agtagctaca ataaaaggaa tattacctca tgctcttatt gaaataccga attttatttg
     1081 gtatcaaggt atgagtcagt atcttttata ccgattattg aaggataggg gaattaaaaa
     1141 tatacttatt tatataaaaa gtaatttaaa atggtatatc atttcttatc ttttattaat
     1201 tttagcagcg ttgatagagg gaattaaatt atgaaaattg aaaatgaatc taaaagttat
     1261 gataaatgta tattgaaaaa tatatcacta gagattgata agggaattta cagagttgaa
     1321 ggagagaatg gttcaggaaa gagcaccctt ctacaacttt tagctgggct agagactttt
     1381 gatagtggtt taaagaattg tgtctccaaa gatgtactat accttgatac caatcagctt
     1441 ggggttgttc catttactat agaagaaaat ttgcagttgt tgtgtgattc ttttcaaatc
     1501 catctatcat ttgaggataa agaacaaatt aatacttttt ttgataataa aatcggagat
     1561 aactatatga cagcatctac tggaacaaaa ttcaaattag gcttatcctt aatttttgct
     1621 aaaaattggg attatatttt tattgatgag actttatcaa cagtggatgc aagaagtatt
     1681 gatatgattg ctaaacgctt aatttccatg aaagaaagct ctactattat atatgtatct
     1741 cataatttat tgaatcaaga attgattagc aaatctcaaa ggattttaat agaggaagga
     1801 cgggtttatg aaatttcaaa caaataatag tttatacaaa ttaatgaatc tgattattta
     1861 tctttttctt ttatatttgt ttattgattt actgatgaag tcgggaattt tagatgaaca
     1921 aattgataaa ttatctgaac tatctaatct ttttacaatt aaaatagaaa caatattgac
     1981 agtgatttct gttgttttca catttatagc aactcttatt gaatatggat tttctctctt
     2041 tctgattaca ttattttttg ataagaataa gaggaacttt ggagatattc ttttatctaa
     2101 aaatataacc ttaagtttta gcattttact ttgttattta tttaatccat cggatataaa
     2161 gtttgcctat ttcagcgtat tgacagtatt actaattggg ataacaaatt atgcgagatt
     2221 taaaaattta agattgacag tagtgttttc tgtaccattt ttatttaatg ctataatgtc
     2281 tattataaat agtttttaga aatactaaaa tttttttctt tacttaataa tgatatgaaa
     2341 tcatttcggt tttgttaact tgtaattctt atattttcta ggtagaacgt ttgttctgcc
     2401 tattttttta tccaaaaagt gcagttggga gggagatagg ctcatttggg aaggaagtcc
     2461 agtttttgtt tagtgattgg ggtaagatag ttgttatcag atgagtttat actcttcgaa
     2521 aatcaaattc aaaccacgtc aacgtcgcct tgccgtatat atgtgactga cttcgtcagt
     2581 cctatctaca acctcaaaac agtgttttga gcagcctgcg gctagtttcc tagtttgctc
     2641 tttgattttc attgagtatt agggaaaagg agatgaatat gaaatttggg aaacgtcact
     2701 atcgtccgca agtggatcag atggactgcg gtgtagcttc attagccatg gtttttggct
     2761 actatggtag ttattatttt ttggctcact tgcgagaatt ggctaagacg accatggatg
     2821 ggacgacggc tttgggcttg gtcaaggtgg cagaggagat tggttttgag acgcgagcca
     2881 ttaaggcgga tatgacgctt tttgacttgc cggatttgac ttttcctttt gttgcccatg
     2941 tgcttaagga agggaaattg ctccactact atgtggtgac tgggcaggat aaggatagca
     3001 ttcatattgc cgatccagat cccggggtga agttgactaa actgccacgt gagcgttttg
     3061 aggaagaatg gacaggagtg actcttttta tggcacctag tccagactat aagccttata
     3121 aggaacaaaa aaatggtctg ctctctttta tccctatatt agtgaagcag cgtggcttga
     3181 ttgccaatat cgttttggca acactcttgg taaccgggat taacattgtg ggttcttatt
     3241 atctgcagtc tatcattgat acctatgtgc cagatcagat gcgttcgaca ctagggatta
     3301 tttctattgg gctagtcatc gtctacatcc tccagcaaat cttgtcttac gctcaggagt
     3361 atctcttgct tgttttgggg caacgcttgt cgattgacgt gattttgtcc tatatcaagc
     3421 atgtttttca cctccctatg tccttctttg cgacacgcag gacaggggag atcgtgtctc
     3481 gttttacaga tgctaacagt atcatcgatg cgctggcttc gaccatcctt tcgattttcc
     3541 tagatgtgtc aacggttgtc attatttccc ttgttctatt ttcacaaaat accaatctct
     3601 ttttcatgac tttattggcg cttcctatct acacagtgat tatctttgcc tttatgaagc
     3661 cgtttgaaaa gatgaatcgg gataccatgg aagccaatgc ggttctgtct tcttctatca
     3721 ttgaggacat caacggtatt gagactatca agtccttgac cagtgaaagt cagcgttacc
     3781 aaaaaattga caaggaattt gtggattatc tgaagaaatc ctttacctat agtcgagcag
     3841 agagtcagca aaaggctctg aaaaaggttg cccatctctt gcttaatgtc ggcattctct
     3901 ggatgggggc tgttctggtc atggatggca agatgagttt ggggcagttg attacctata
     3961 ataccttgct ggtttacttt accaatcctt tggaaaatat catcaatctg caaaccaagc
     4021 ttcagacagc gcaggttgcc aataaccgtc taaatgaagt gtatctagta gcttctgagt
     4081 ttgaggagaa gaaaacagtt gaggatttga gcttgatgaa gggagagatg accttcaagc
     4141 aggttcatta caagtatggc tatggtcgag acgtcttgtc ggatatcaat ttaaccgttc
     4201 cccaagggtc taaggtggct tttgtgggga tttcagggtc aggtaagacg actttggcca
     4261 agatgatggt taatttttac gacccaagtc aaggggagat tagtctggat ggtgtcaatc
     4321 tcaatcagat tgataaaaaa gccctgcgcc agtacatcaa ctatctgcct caacagccct
     4381 atgtctttaa cggaacgatt ttggagaatc ttcttttggg agccaaggag gggacgacac
     4441 aggaagatat cttacgggcg gtcgaattgg cagagattcg agaggatatc gagcgcatgc
     4501 cactgaatta tcagacagaa ttgacttcgg atggggcagg gatttcaggt ggtcaacgtc
     4561 agagaatcgc tttggcgcgt gctctcttga cagatgcgcc ggtcttgatt ttggatgagg
     4621 cgactagcag tttggatatt ttgacagaga agcggattgt cgataatctc atggctttgg
     4681 acaagacctt gattttcatt gctcaccgct tgactattgc tgagcggaca gagaaggtgg
     4741 ttgtcttgga tcagggcaag attgtcgaag aaggaaagca tgctgatttg cttgcacagg
     4801 gtggctttta cgcccatttg gtcaatagct agaaagagga gaggatgaaa ccagaatttt
     4861 tagaaagtgc ggagttttat aatcgtcgtt accataattt ttccagtagt gtgattgtac
     4921 ccatggccct tctgctcgtg tttttacttg gctttgcaac tgttgcagaa aaggagatga
     4981 gtttgtccac tagagctact gtcgaaccta gtcgtatcct tgcaaatatc cagtcaacta
     5041 gcaacaatcg tattcttgtc aatcatttgg aagaaaataa gctggttaag aagggagatc
     5101 ttttggttca ataccaagaa ggggcagagg gtgtccaagc ggagtcctat gccagtcagt
     5161 tggacatgct aaaggatcaa aaaaagcaat tggagtatct gcaaaagagc ctgcaagaag
     5221 gggagaacca ctttccagag gaggataagt ttggctacca agccaccttt cgcgactaca
     5281 tcagtcaagc aggcagtctt agggctagta catcgcaaca aaatgagacc atcgcgtccc
     5341 agaatgcagc agctagccaa acccaatccg aaatcggcaa cctcatcagt caaacagagg
     5401 ctaaaattcg cgattaccag acagctaagt cagctattga aacaggtgct tccttggccg
     5461 gtcagaatct agcctactct ctttaccagt cctacaagtc tcagggcgag gaaaatcccc
     5521 aaactaaggt tcaggcagtt gcacaggttg aagcacagat ttctcagtta gaatctagtc
     5581 ttgctactta ccgtgtccag tatgcaggtt caggtaccca gcaagcctat gcgtcagggt
     5641 taagcagtca attggaatcc cttaaatccc aacacttggc aaaggttggt caggaattga
     5701 cccttctagc ccagaaaatc ttggaggcag agtcaggtaa gaaggtacag ggaaatcttt
     5761 tagacaaggg gaaaattacg gcgagtgagg atggggtgct tcatcttaat cctgagacca
     5821 gtgattctag catggttgca gaaggtgccc tactagctca actttatcca tctttggaaa
     5881 gagaagggaa agccaaactc acagcttatc taagttcaaa agatgtagca agaatcaagg
     5941 tcggtgattc tgttcgctat actacgactc atgatgccgg gaatcaactt ttcctagatt
     6001 ctactattac aagtattgat gcgacagcta ctaagactga gaaagggaat ttctttaaaa
     6061 tcgaggcgga gactaatcta acttcggagc aggctgaaaa acttaggtac ggggtggaag
     6121 gccgcttgca gatgattacg ggcaagaaaa gttacctacg ttattatttg gatcaatttt
     6181 tgaacaaaga gtaatgttcg tgtttttaga gttaaataat ttttaaactg tgagaaagat
     6241 tcttcttgca gtttttttct ttacaatttt tgaaaaatat ctgctattta ttcggttaaa
     6301 ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa aggcgaactt
     6361 taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata caactgagga
     6421 tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaacg gtgtcaagaa
     6481 ggagcagatt gcaggtaagg gagtcttgaa taatcagatc tcatctttta tttttgagaa
     6541 attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca cggaacaact
     6601 caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata ctgctggttc
     6661 cttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga ttgtcgaatt
     6721 ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg tgaaattcct
     6781 acagattgcg ggtgaccagc agattgccta cttgaaggaa gaaacgcgtc gtatcaatga
     6841 actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta agctagagtt
     6901 cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag ataactgccg
     6961 cttgtgggac gctgatggca accacatgga taaggatgtt ttccgtagag gattgggaga
     7021 actaaccgac gtttatgaga ttgtttggga aaagttgcag gaattgaaat aatctgtttg
     7081 caacggaaaa ccttcgtctc tcaactaaaa ggactcaggc tgaaaaggtc ccccagacct
     7141 tttcactctg tagagaacta ggtgaactaa cagatgttta cgaaattgtc tgggaaaagt
     7201 tgcagggttt aaaataacaa cctcaaggct gtttgggaat attgcaagag ctgaaataaa
     7261 ggaataagaa ttgatggata aacgtatttt tgttgaaaaa aaggctgatt ttcaggtcaa
     7321 gtcagagagt ttggttagag agctccagca caacttggga ctgtcaagct tgaaaagtat
     7381 tcgtattgtg caagtatatg atgtatttga cttggctgag gacttgtttg cacctgcaga
     7441 gaagcacatt ttctctgagc aggtaaccga ccatgtttta gatgaagtat ctgtgcaggc
     7501 ggatcttgct aactatgctt tctttgccat tgaaagtctg ccagggcagt ttgaccagcg
     7561 tgcagcttcg tcacaggaag ccttgctttt gttgggaagt tcgagtgacg tgacagtcaa
     7621 cacagcccaa ctttacttgg tgaataaaga tattgatgcg actgagttga aagctgtcaa
     7681 aaactacctg ctcaatctag ttgattctcg tttcaaggat atcacgacag ggattgccaa
     7741 gcaggagttt tcagagtcag acaagaccat tccaaaattg actttctttg aaagctatac
     7801 agcagaagat tttgctcgct acaaggccga acaagggatg gccatggaag tggatgattt
     7861 gctctttatc caagactact ttaagtcaat cgggcgcgtg ccaactgaga ctgaacttaa
     7921 ggttttggac acttactggt ctgaccactg ccgtcatacg acttttgaga cagagttgaa
     7981 acacatcgac ttttcagctt ctaaatttca aaagcaattg cagtcaacct atgacaagta
     8041 tattgccatg cgcgaggaat taggtcggtc tgaaaaacca caaaccttga tggatatggc
     8101 gactattttc ggtcgttatg agcgtgctaa tggacgattg gatgatatgg aagtctctga
     8161 cgaaatcaat gcctgctcag ttgaaattga agtggacgtt gatggtgtca aggaaccttg
     8221 gctcctcatg tttaaaaacg aaacccacaa ccatccaaca gaaattgagc catttggtgg
     8281 agcggctacc tgtattggtg gagctattcg tgatccgttg tcaggccgtt cctatgttta
     8341 ccaagccatg cgtatttcag gtgctggtga tattacagca ccgatttcgg aaactcgcgc
     8401 tgggaaattg ccacaacaag tcatttctaa aacagcagct catggttatt cttcatatgg
     8461 taaccagatt gggcttgcca caacctacgt tcgtgaatac ttccacccag gctttgtagc
     8521 taaacgtatg gaacttggtg ccgttgttgg tgcggctccc aagggcaatg ttgtccgtga
     8581 aaaacctgaa gcaggtgatg tgatcatcct tctcggaggt aaaacaggtc gtgatggtgt
     8641 cggtggtgcg acgggctctt ctaaggttca aacagttgag tctgtagaga ctgctggtgc
     8701 tgaggttcaa aaaggaaatg ccatcgaaga acgcaagatt cagcgcctct tccgtaatgg
     8761 caatgtcact cgtctgatca agaagtccaa tgactttggg gcaggcggtg tctgtgtggc
     8821 tatcggtgaa ttggcagacg gtcttgaaat cgacctcaac aaggtgcctc ttaaatacca
     8881 gggcttgaat ggtacagaaa ttgccatctc tgaatcacaa gaacggatgg cggtcgtggt
     8941 tcgtcctgaa gatgtggata ccttcgttgc cgaatgtaac aaagaaaata ttgatgctgt
     9001 tgtggtggcg acagtaactg aaaaaccaaa tcttgtcatg cactggaatg gtgagacaat
     9061 cgttgacttg gagcgtcgtt tccttgacac caatggtgtg cgcgtggttg tcgatgccaa
     9121 agttgtggac aaggatgtca aactcccaga agagcgtcaa acatctgctg aaacactgga
     9181 atcagatacc cttacggttc tatctgacct caaccatgca agtcaaaaag gattacagac
     9241 tatctttgac tgctctgttg gacgctcaac ggttaatcac ccacttggtg gtcgttacca
     9301 actcacacca actgaggcat ctgtgcagaa attgccagtt caacacggtg tgactcatac
     9361 tgcgtcggtc attgctcaag gtttcaaccc atatgtagct gaatggtctc cataccacgg
     9421 tgctgcttat gcggttatcg aagcaactgc tcgtttggtg gctgctggtg ccaactggtc
     9481 taaggctcgt ttctcttacc aagaatattt cgagcggatg gacaagcaag cagagcgttt
     9541 cggtcagcca gtagctgctc ttctaggttc tattgaagca caaattcagc ttggcttgcc
     9601 atctatcggt ggtaaggact ccatgtctgg tacctttgaa gaattgaccg ttccgccaac
     9661 cttggttgcc tttggggtga cgacggcaga tagccgtaag gtgctctctc cagaatttaa
     9721 agctgttggg gaaaatatct actacatccc aggtcaagcc ctctctgcag agattgattt
     9781 tgacttgatt aagaaaaatt ttgctcagtt tgaagcaagc caagctgacc ataaagtgac
     9841 gtctgcatca gctgtcaaat acggtggtgt agttgaaagt ttggctcttg ctacctttgg
     9901 aaactatatt ggtgcagagg tgaccttgcc tgaacttaaa acagctttga cagctcaatt
     9961 aggcggcttt gtcttcacat ctcctgaaga aattgctgga gtagagaaga ttggacaaac
    10021 gaaagcagac tttacactga ctgtcaacgg tgtgaagcta gatggacaca agcttgacag
    10081 tgcatttcaa gggacattgg aagaagttta cccaacagaa tttacccaag cgaaagaact
    10141 agaagaagta ccagctgtgg catcagatgt tgtgattaaa gccaaagaaa aggttgaaaa
    10201 acctgtggtt tacatcccag tctttccagg aaccaactca gaatatgatt cagctaaggc
    10261 cttcgaaaaa gaaggtgcag aggtcaattt ggtgccattc gtgaccttga atgaagaagc
    10321 tattgtcaag tcagttgaaa ctatggttga caatatcgac aagactaata ttctcttctt
    10381 tgccggtgga ttctcggctg cggatgaacc agatggttca gctaagttta tcgtcaatat
    10441 cctgcttaat gaaaaagtgc gtgtggctat tgatagcttt atcgcccgtg gtggcttgat
    10501 tatcggtatt tgtaatggat tccaagcctt agtcaaatcg ggtctcctac catacggaaa
    10561 ctttgaagat gctaacagta ctagtccaac cctcttctac aatgatgcca accaacacgt
    10621 ggccaagatg gtggaaactc gcattgccaa taccaactca ccatggttgg ctggtgtgca
    10681 agtgggcgat atccacgcta ttcctgtttc gcacggtgaa gggaagtttg tcgtgacggc
    10741 tgaggaattt gcagagctcc gtgacaatgg acaaattttc agccaatacg ttgactttaa
    10801 cggtaaacca agtatggatt ctaagtacaa tccgaatggt tctgtccatg ccatcgaagg
    10861 aattaccagc aagaatggtc aaatcatcgg taagatgggc cactcagaac gttatgagga
    10921 tggtcttttc caaaatatcc caggcaataa agaccaacac ctgttcgcat cagcggttaa
    10981 acatttcact ggaaaataag acttacagat tttctaatag atagtatcag taatgtaaaa
    11041 gtcatgtaaa tctagctctt gatgattaca aatgaaaatt aggtataaaa aatgacatac
    11101 gaagtaaaat ctcttaatga agaatgtggt gttttcggta tttggggaca tccagatgct
    11161 gctaagttga cctattttgg actccacagt cttcaacacc gtggtcagga gggggcagga
    11221 atcctctcca acgatcaagg acaactgaag cgccatcgtg acatggggct tttatcagaa
    11281 gttttcagaa atccagctaa tttggataaa ttgacaggag ctggtgcgat tgggcatgtg
    11341 cgttatgcga ctgctggcga agcttctgta gataacatcc agcccttcct cttccgtttt
    11401 cacgatatgc agtttggctt ggctcataat ggaaatctga ccaatgcagc ctctctcaag
    11461 aaagaactgg aacaaagagg agcaattttc agcgcgactt cggactctga aatcttggct
    11521 cacctcattc gtcgcagtca taatcctagc ctgatgggca aaatcaagga agcgctcagc
    11581 cttgtcaaag gtggttttgc ctatatcttg ctgtttgagg acaagttgat tgcggctctt
    11641 gaccctaatg gctttcgtcc gctttctatc gggaaaatgg ccaacggagc ggtggttgtt
    11701 tcctctgaaa cctgtgcttt tgaggtcatt ggtgccgagt ggattcgtga tttgaagcca
    11761 ggtgagattg tgatcattga tgacgagggc attcagtatg acagctatac agatgatacc
    11821 cagttggcga tttgttctat ggagtatatc tactttgctc gccctgattc taatatccac
    11881 ggtgtcaatg tccatacggc acgtaagaga atgggagcgc aattggcgcg agaatttaag
    11941 catgaggcag atattgtagt tggtgtgccc aattcttccc taagcgcggc tatgggattt
    12001 gcggaagaat caggcttacc aaatgaaatg ggtctgatca aaaaccaata cacccagcga
    12061 acttttatcc aaccgactca agaattgcgg gagcaaggag tgcggatgaa actgtctgct
    12121 gtttcgggtg ttgtcaaagg caaacgtgtg gtcatggtgg atgattccat tgtacgtgga
    12181 acaacctctc gtcgtatcgt tcagctcttg aaagaagcgg gtgcgactga ggttcacgtt
    12241 gccattggaa gtcctgcact agcgtatcca tgtttctacg ggattgatat ccagacccgt
    12301 caggagctga ttgcagccaa tcatacggtc gaagaaactc gccaaatcat tggtgcggac
    12361 agtctgactt atctttcaat tgatagcttg attgagtcga ttggtatcga aacagatgcg
    12421 ccgaacggtg gtctctgtgt cgcttacttt gacggtgact acccaacgcc tctctatgac
    12481 tacgaagaag actatcgtag aagtttggaa gaaaagacca gtttttacaa gtaggcgaca
    12541 gattctccat taaagaaaag gaaaaaacaa atgacaaata aaaatgcata tgcccagtcg
    12601 ggtgtggatg ttgaagcggg ttatgaagtt gttgaacgga ttaaaaagca cgtggcccgt
    12661 acggagcgtg caggtgtcat gggagctctt ggtggctttg gtggtatgtt tgacctttcc
    12721 aagactgggg ttaaagaacc cgtcttgatt tcagggactg acggtgtcgg aaccaagctc
    12781 atgttggcta tcaagtacga caagcacgat accatcgggc aggactgtgt ggccatgtgt
    12841 gtcaacgaca tcattgctgc aggtgcggac cccctctatt ttctcgacta cgtagcgaca
    12901 gggaagaatg aaccagctaa gctagaacaa gtggttgctg gtgtggcaga aggttgtgtg
    12961 caggctggtg ctgccctcat cggtggggaa acggctgaaa tgccgggcat gtacggcgaa
    13021 gacgactatg acttggctgg ttttgcggtc ggtgtggctg aaaaatctca aatcattgac
    13081 ggttcaaagg tggtagaggg agatgttctt ctcggacttg cttcaagtgg gattcactca
    13141 aatggttact ctttggttcg tcgtgtcttt gcggattaca caggtgagga agtcctacca
    13201 gaattggaag gcaagaaact taaggaagtt ctacttgagc cgactcgtat ctatgtcaag
    13261 gctgtcttgc cgctcatcaa agaagagttg gtcaacggca ttgcccacat cacaggtggt
    13321 ggctttatcg aaaatgtccc tcgtatgttt gcagatgacc tagctgctga aattgatgaa
    13381 agcaaagttc cagtgcttcc aattttcaaa gcccttgaaa aatatggtca gattaaacac
    13441 gaagaaatgt ttgaaatctt caatatgggt gtgggactta tgttggcggt cagccctgaa
    13501 aatgtagagc gtgtaaaaga attgttggat gaagcagtct atgaaattgg tcgcatcgtc
    13561 aagaaagaaa acgaaagtgt cattatcaaa tgaaaaaaat agcggttttt gcctctggta
    13621 atggctcaaa ttttcaggtg attgccgaag aatttccagt ggagtttgtc ttttcagacc
    13681 atcgtgatgc ctatgtgctt gagcgtgcaa agcagctcgg cgttctgtcc tatgcttttg
    13741 aactcaagga gtttgagagc aagacagact acgaagcagc ccttgtcgaa ctcttggaag
    13801 aacaccagat tgacttggtt tgcctagcag gctacatgaa aatcgttgga ccaaccttat
    13861 tgtcggctta tgaaggtcgg attgtcaaca ttcatccagc ctacttgcca gaatttccag
    13921 gagctcatgg gattgaggat gcttggaatg ctggcgtggg tcagtctggt gtgaccattc
    13981 actgggtgga ttcgggtgtg gatacaggcc aggtcatcaa acaggttcgt gtgccacgac
    14041 tagctgatga taccattgac agatttgaag ctcgcatcca tgaagcagag tacaggttgt
    14101 atccggaagt agtgaaggct ctatttacag attgactttt tgatgattca tatgatatct
    14161 ttgattttaa attggagtca gtgtttgttg aagacggctt caaacggagg tatttgtaat
    14221 gttagaatct aaaaaaacaa ctcgatatgt attttatgtc tatctgatgt tattaacttg
    14281 gggaatctta tttaagtttg aaacaaatcc tgaatttata gcatttttct tagctccaag
    14341 gtatatcaat tggattccat tttcagaacc actaatagtc gatggaaaaa ttgtttttgc
    14401 tgaaatgtta tttaatctga tttcctttat tccattaggt gtttgtttcc ctttgataaa
    14461 aactaattta tctagtttaa gaatagtcgg gacaggtttc ttgattagtt tattgtttga
    14521 gtgcttacag tatattttag caataggtat aacagatata acggatttga ctttaaatac
    14581 gctaggtgtc tgtgtaggct tactgattta tcaaattttt ataagagtgt tcaaatcaca
    14641 gactagaaaa tggatcaata tcttaggtat gcttagcctt ggttttgctt atcttgtttt
    14701 actgttactg catttaattg gtgtttaact aatgattaaa aaggagaata taatgactaa
    14761 acgcgtctta atcagcgtct cagacaaagc gggcattgtt gaatttgccc aagaactcaa
    14821 aaaacttggt tgggagatta tctcaacagg tggaactaag gttgcccttg ataatgctgg
    14881 ggtggatacc attgctatcg atgatgtgac tggtttccca gaaatgatgg acggtcgtgt
    14941 gaagaccctc cacccaaata tccacggagg gcttctcgct cgtcgtgact tggatagcca
    15001 cttggaagcg gctaaggaca acaagattga gctcattgac cttgtggtgg tcaaccttta
    15061 cccatttaag gaaactatcc ttaaaccaga tgtgacttat gctgatgcag ttgaaaatat
    15121 cgatattggt gggccgtcta tgcttcgttc agcagcgaaa aatcatgcca gtgttacagt
    15181 tgtggtagat cctgctgact acgctgtggt tttggacgaa ttggcagcaa acggcgaaac
    15241 ctcttatgaa actcgccaac gtttagcagc caaagtattt cgtcacacag cggcttatga
    15301 cgccttgatt gcagaatact tcacagctca agtgggtgaa agcaagcctg aaaaactcac
    15361 tttgacttat gacctcaagc aaccaatgcg ttacggtgag aatcctcaac aagacgcgga
    15421 cttttaccag aaagctttgc ctacagatta ctctattgct tcagccaaac agctcaacgg
    15481 gaaagaattg tcatttaata atatccgtga tgcagatgct gctatccgta tcatccgtga
    15541 cttcaaagat agtccaaccg ttgtggctct caaacacatg aatccatgtg gaattggtca
    15601 agctgatgac atcgagactg cttgggacta cgcttatgag tctgacccag tatctatctt
    15661 tggtgggatt gtcgtcctca accgtgaggt ggatgctgcg acagctgaga agatgcacgg
    15721 cgttttcctc gaaatcatca ttgcaccaag ctatacggat gaagcgctag ctattttgat
    15781 caataaaaag aaaaacttgc gtatccttgc cttgccattt aatgctcaag aggctagcga
    15841 agtggaagca gaatacacag gtgtagtcgg tggacttctc gtgcaaaatc aagacgtggt
    15901 caaggaaagc ccagctgact ggcaagtggt gaccaaacgt cagccaactg agacagaagc
    15961 gactgctctt gagttcgctt ggaaggctat caagtacgtc aaatcaaatg gtattatcgt
    16021 gaccaacgac cacatgacac ttggtgttgg tccaggtcaa accaaccgtg tggcttctgt
    16081 tcgccttgcc attgaccaag ccaaagatcg tctgaacggg gcggtccttg cttcagatgc
    16141 cttcttccca tttgcggata acgtggaaga aatcgccaaa gcaggaatta aggccatcat
    16201 ccagcccggt ggctctgtcc gtgaccaaga atccatcgaa gcagcggata aatacggctt
    16261 gactatggtc tttacaggtg tgagacattt tagacattaa gaagataaaa gggaagaaaa
    16321 cagtttcttt ccttttttgg cttaaaatgc taactgaaac aagattaaaa cgaacttttt
    16381 tgatataatg ttggtaaata attcgcaaaa gaggttgagg aatgaaactg cttgttgtcg
    16441 gttctggtgg tcgtgagcat gcgattgcta aaaagttact tgaatcaaaa gacgtggaaa
    16501 aagtctttgt agctcctggg aatgatggga tgactctgga tggtttggaa ttggtaaata
    16561 tctctatttc cgaacattct aaattgattg acttcgcaaa gaccaatgat gttgcttgga
    16621 cctttatcgg tccagatgat gcccttgctg ctggtatcgt ggatgatttt aaccaagctg
    16681 ggcttaaggc ctttggtccg actagggctg cagcggagct ggagtggtcc aaggattttg
    16741 ccaaggaaat catggtcaaa tatggtgttt cgacagcagc ctatggcaca ttttcagatt
    16801 tcgaggaagc caaggcctat atcgaaaagc atggtgcgcc tatcgtagtc aaggcggatg
    16861 gcttggcgct tgggaagggt gtcgtcgttg ctgagacggt tgagcaagcg gtcgaagccg
    16921 ctcatgagat gcttttggac aataaatttg gtgactcagg tgcgcgcgtg gttattgagg
    16981 aattccttga aggagaggaa ttttcactct ttgcctttgt caatggtgat aagttctaca
    17041 tcatgccaac ggctcaggac cacaaacgtg cctacgatgg cgacaaaggg cctaacacgg
    17101 gtggtatggg tgcctatgcg ccagttccac acttaccaca gagtgtagtt gatacagcgg
    17161 ttgacaccat tgtcaagcca gttctagaag ggatgattaa agaaggtcgc ccttatctag
    17221 gtgtcattta cgcagggctt atcttgacag cagacgggcc gaaggtcatc gagttcaact
    17281 ctcgatttgg agatcctgaa actcagatta tattgcctcg tttgacctct gactttgctc
    17341 aaaatatcac agatatcctg gatagcaagg agccaaatat catgtggacg gacaagggtg
    17401 tgactctggg tgtggttgtc gcatccaagg gctacccgct agactatgaa aggggcgttg
    17461 agttgccagc caagacagaa ggcgatgtca tcacctacta tgcaggggct aagtttgcgg
    17521 aaaatagcag agcactgctc tcaaacggcg gacgagttta tatgctggtt accacagtag
    17581 ccaccgtcaa agaagcccaa gccagcatct accaagaact atcccaacaa aaaatagaag
    17641 gactcttcta ccgaacagat atcggaagca aggcaattaa gtaaagatat aagaataacg
    17701 cgccgtagtc gccaaacacg ataatggtcg tcgtggtgaa aagaccagaa cagtgaatgt
    17761 tctggtcagg gggaaacttg gagaccgtag gctcaaagtt taggaatgaa accgaaggtt
    17821 tgcttccgcc tccatcacct aagaccatta tcaaaaagaa aaataaaaat tcacaaaata
    17881 cgttaatgat cgtatggttt gcgagcgtta gcgagctaat atagaacaat caccgccgtt
    17941 gtgaaagaac gattggatga taatccaatc gttcagggaa attggaagac cttgggtttc
    18001 caatttaggc atgagacacc tttggtggct gctgccgtcc ctcacaagct aaggtgattg
    18061 ttgaaaaaga ggaaaaagga gaagaaatga aaccagtaat ttccatcatc atgggctcaa
    18121 aatccgactg ggcaaccatg caaaaaacag cagaagtcct agaccgcttc ggtgtagcct
    18181 acgaaaagaa agttgtttcc gcacaccgta caccagacct catgttcaaa catgcagaag
    18241 aagcccgtag tcgtggcatc aagatcatca tcgcaggtgc tggtggcgca gcgcatttgc
    18301 caggcatggt agctgccaaa acaacccttc cagtcattgg tgtgccagtc aagtctcgtg
    18361 ctcttagtgg agtggattca ctctattcta tcgttcagat gccgggtggg gtgcctgttg
    18421 cgaccatggc tatcggtgaa gctggagcga ctaacgcagc tctctttgcc ctccgtctcc
    18481 tctctgtaga agataagtcc attgcggatg cacttgccaa ctttgctgaa gaacaaggaa
    18541 aaatcgcaga ggagtcgtca aatgagctca tctaaaacaa tcggaattat cggtggcggt
    18601 caactgggtc agatgatggc catttctgct atctacatgg gccacaaggt tatcgcgctg
    18661 gatcctgcgg cggattgccc ggcctctcgc gtggcggaaa tcattgtggc accttataac
    18721 gatgtggacg ccctccgtca gttggcagac cgttgcgatg tcctcactta cgagtttgaa
    18781 aatgtcgacg ctgacggttt ggatgccgtt atcaaggatg gacaactccc tcaaggaaca
    18841 gatctgctcc gcatttcgca aaatcgtatt tttgaaaagg actttttgtc aaacaaggct
    18901 caagtcactg tggcacccta caaggtcgtg acttctagcc tagacttggc agatatcgac
    18961 ttgtcgaaaa actatgtcct caagactgcg actggtggct acgatggtca tggacaaaag
    19021 gttattcgtt cagaagcaga cttggaagca gcctatgcgc tagcagactc agcagactgc
    19081 gtcttggaag aatttgtcaa ctttgacctt gagatttctg tcatcgtgtc aggaaatggc
    19141 aatgaggtga cgtttttccc agttcaggaa aatatccacc gcaacaatat cctatctaag
    19201 accatcgtac cagcccgcat ttctgaaagt ctagcagaca aggctaaagc tatggcagtg
    19261 cgaatcgcag aacaactcaa cttgtctgga actctctgtg tggaaatgtt tgcgactgat
    19321 gatgacgtta ttgtcaatga aatcgcccca cgaccacata actctgggca ctattctatt
    19381 gaagcctgtg atttctctca gtttgacacc catattctgg gtgttctcgg agcaccatta
    19441 ccagtcatca aactccatgc gccagccgtt atgcttaatg tcctcggtca gcatgtcgag
    19501 gctgctgagc aatatgtgac agaaaattca agcgcccacc tccacatgta tggtaaaata
    19561 gaagcaaagc ataatcgtaa gatgggacat gtgactttgt ttagtgatgt gccggatagt
    19621 gtggatgagc ttggggaagg gattgatttt taggacaagt ctatgataca aattatcgtt
    19681 aatacattta ttgaaaagga taagactgga gcagttgttg aagtgttgta tgccagtgct
    19741 gaccaagata aggtacaagc taaatatgaa gaactagctg cacaataccc cgaaaattat
    19801 ttagctatct atgatgtacc gctggatacg gatttgaata cactagatca ttacccgtct
    19861 gtgtttattg gaaaagagga gtttgagtag aaatcttggt ttacctagat agcttattcc
    19921 caacagctta agaagaaagg aaaaattaac acatgatcaa ccgttactct cgccctgaga
    19981 tggcgaatat ttggagtgaa gaaaataaat accgtgcttg gcttgaggtg gaaatcctct
    20041 ctgacgaggc atgggctgag ttgggggaaa tccctaagga agatgtggct ttgattcgca
    20101 agaaggcgga ctttgacatc gaccgtattt tggaaattga gcaggagacg cgccacgatg
    20161 tggtggcttt cacgcgtgcg gtttctgaga ctcttggtga agagcgcaag tgggttcact
    20221 atgggttaac ttctactgac gtggtggata ctgcttatgg ttacctctac aagcaggcca
    20281 acgacatcat ccgtcgtgac cttgaaaact tcactaatat catcgctgac aaggccaagg
    20341 agcacaagtt caccatcatg atggggcgta ctcatggtgt gcacgctgag ccgacaacct
    20401 ttggtcttaa attagcaact tggtacagcg aaatgaaacg caatatcgag cgcttcgagc
    20461 atgcggctgc tggtgtagaa gctggtaaga tttctggtgc ggttgggaac tttgccaata
    20521 tcccaccatt tgtagaggag tatgtctgcg ataaacttgg catccgtgcc caagaaatct
    20581 ctacacaagt ccttcctcgt gaccttcacg ctgagtactt tgcggttctt gccagcattg
    20641 cgacttcaat cgaacgtatg gcgactgaga ttcgtggtct acaaaaatct gagcaacgcg
    20701 aagtagaaga gttctttgct aaagggcaaa aagggtcttc agcaatgcct cacaaacgca
    20761 acccaatcgg ttctgaaaat atgactggtc tggcgcgtgt cattcgtggt cacatgatta
    20821 cggcttatga aaacgtcgct ctctggcacg aacgcgatat ttctcactca tcagctgagc
    20881 gtatcatcac accagatacg accattttga ttgactacat gctcaaccgt tttggaaata
    20941 tcgtcaagaa cttgacagtc ttcccagaaa atatgatccg aaacatgaac tcgacttttg
    21001 gtcttatctt tagccaacgg gctatgttga cattgattga aaaaggcatg acccgtgagc
    21061 aagcctatga cttggtgcaa ccaaaaacag cctactcttg ggacaaccaa gtagacttta
    21121 aaccacttct tgaggcagat tcagaagtaa catcacgtct cactcaagaa gaaatcgatg
    21181 aaatcttcaa cccagtttat tacaccaaac gagtggatga tatctttgaa cgtcttggac
    21241 taggtgatta attaaaaaat aaacagcgag cttcaatctc gctgtttatt ttttatcgaa
    21301 aagacttagt cttcttttct tttagtgagt ccataggctg ctagtgtgga catgagtcct
    21361 gcgactacta gtcctgcaga atcgtgagtt cctgtttcag gaagtttttt ctctgttacc
    21421 acaggagctg gatcttgagg aagagctttg ctttcctcag caggagcagt tgatggagct
    21481 ggttggcttg ggatttctag ttttggtttt tcttcagcaa tagcggcttg tccgttttca
    21541 tcgcctacat gtgttaccat agttccgact tcgactattt gagtaacggc ttcctgtgct
    21601 acgacactat ttacaagtgt tttcacttcc ttaccatcgg cagaagtgct cacagagtag
    21661 aagttgctac gatgtccatt gacgccctta gtaatgactt gtgtttttcc tttgagtaag
    21721 agtggatttt cacgagtcac tgtggtaaat ggaatttctt cttcttggat atccagtcta
    21781 ggttttacct cagtagttgg tgcaagacca ctttcatcac ccttgtgagt tacaggagag
    21841 ccaacttcaa ccacttggtt tataacttct ttggttacct ggctatcaag gactgtttct
    21901 gttgtttttc cattttcagt gagtacagag atgtaatgag ttcgttcacc tttgactcct
    21961 gctgtgataa tattttcctg accagctggg aggttaggat tttctttctt gataacttca
    22021 aatggaattt cttcagttct tgtgatgagt tctggtctgg tttcaacatt ggcagccact
    22081 tcattttcat ctaggcttcc tgaatgagtt gcagctggtt tgaggccttg aagagcggct
    22141 tttaggttgg ctacaagtgt gtcaagctca gcttgtttat tacggttgag gttgtaattt
    22201 agagctgttt tagctgcgtc aagggcctca agactttctt tactatatcc ttctaagttt
    22261 gtaggaattt tagctaattc ttcgcggaga gcattataat tagcacggaa gtagtctttg
    22321 ttgtggtctg caaaggcagt catgagttca aagatttcct cttccttgta ctcagcgctt
    22381 ggtctatctg cccagattga aagcatactt ccgactgttg gaagatctac ttcaggatat
    22441 ttggtagaag ctagttgatt gaatggtgtt tttccagtat tctcaatagc tttcttgagg
    22501 aaaccaccac catcttctgg tttttgacca agaatgtagt accagtcacc gttggtattc
    22561 aagaatttat agcctttgct tgctaggtat tgaggtgatg cgaggttata tccccaccag
    22621 cctttagacc agtaagaaat caagacatct ttgtcaaact gaacatcgtc cttgtcttca
    22681 tagtagaagc catcgttgaa ggccattggt tgaagccctc tttctttggc catagctgcg
    22741 agggtgttgg catattcggc aaatttgcca tagagttgat accacttgag gtagtaccag
    22801 ccttgggcac tagtcgcatc gttggcgtat tcgtcagtac caaagttgaa aatctttgtt
    22861 ttacctgcaa agaagtccat gtatttaccg atgagggctt ttacaaagtt catcgcttct
    22921 tcgtttttca agtccatagt tgtttttgaa actttatcaa agtgggcttg aggattttta
    22981 atacctaatt tttccatggc aaccagcata gcatccatgt gacctggact gttaatagct
    23041 gggatgagac cgatgtcctt agatttagcg tattcaatta gctctgtcac ttctgcctgt
    23101 gttagtgcag taccgtttgg atcgtcgtag taagctttag ttccttcgat aatagctttt
    23161 ttaacgtcat cactagcata ggtttttccg ttggcagtaa tggtcatatc atcgagtaga
    23221 aagcgaagtc cgtcatttcc tagaaggaga tggacatcag aatatccgag ctcactggcc
    23281 ttgtctacga tgcgtttgag ctggttcaga gtaaagtatt tgcgtccagc atcgattgag
    23341 attaccttgt ttttggcaag tttttcaacc tcacgtttag cttcttcttc tttttgagct
    23401 tcaggcgtga gggtcaagtt gttgacagtt tcttgaagtt tagcaatggc ttgatcaatc
    23461 gtatcttgtt gggcacggct aaggttgcta tcgagagagc gaatagcttt ttcagcttct
    23521 tttacggccg cgacgctttc tgcagtataa cggttcaggt cttttggtac ctcgttaagt
    23581 gcttgctctg cagattcata atcagctgcg aagtattcag cgttggcatt tgcaaaatga
    23641 cgcatgagtt tgaagaggcg tgatggtgaa taacgtgcag atggagtgtc agcccaagca
    23701 gctaccatac caccgatgat tgggatatca gctccttctg tttttggtac agaagtgatt
    23761 ggtgtgtttt taataccatt gagcccctga tcgagattgt accagccttg gccatcagcg
    23821 tttcgtccaa gaacgtagta ccaagcatca ttggtattaa ggatttggtg acctttttca
    23881 gctagtagtt tagaagaagc gacatcgtag cctccccaac caccagtcca catagaaacg
    23941 atgatgtctt tgtcaaaact accaaagctt gtgtcgctat tgtagtagat accgtcgtta
    24001 aaggccattg gtttgagacc gtgcgatttt acaatacgag cgaggtcatt ggcgtaggca
    24061 ataaattttt catagccttt tacagggtag ccttcgtttg gatagtattt atcagcttga
    24121 agcacactcc aacctttagc atctgtcgca tcattggcat attcatcaag tccgatgttg
    24181 aagatttcag tctttttcgc gaaataagca gcatacttgt cgataagggc ttttgtaaaa
    24241 gcgacagctt gttcgttgtc aagatcgaca gtacgggctg atttcttccc aaaatagcta
    24301 aagttagggt tttggattcc caattctttc atggcattga gaatcgcatc catgtgtcca
    24361 ggactattta ctgtcggaat gagaccgata cctttatctt tggcatagtt aatcagatct
    24421 gtcatttgac tttctgttaa gtgattgccg tttggatcgt tgtaataatc atttgtacct
    24481 ttttcaatgg cgcgtttgac atcgtcactg gcataggtct tgccgttagc tgtgatgctc
    24541 atatcgtcca acatgaaacg gagtccatca tttccgacta ataggtgtaa atcagtgtag
    24601 ccataatgtt tcgctttatc gatgatttcc ttgagctgtt ctggtgagaa atatttacgt
    24661 ccagcatcaa tagaaacaat tttctttttc gctagttttt catttacagt tgcagcacgt
    24721 tcctttcctg tctctgtttc cggtttgtca gcctctgctt tcgcttcatc ttttttagct
    24781 ggtttatcct tgtcagtctt gtctgtattt gactctttag aatcaacctc tttcgcttct
    24841 tcctttttag ggctagcttc ttcttccttt ttattagcag tttctttttc agcagaagtt
    24901 ggagttacca cctctgcttt atcactagga gttgaactaa cttcctcttg tggtttttct
    24961 tctgtttttg gaagactagc taccttatca gtagctggag tttctgtttc tacagttttt
    25021 ggagcttctg tttctacagt ttttggagct tctggttgaa gctctgcttt aggtgtttcc
    25081 tcagtccgat tttcggatga ttgaggggaa tcagaaaccg tatggatggt cggttggttt
    25141 tctgtagtag taggagtaac tccatcggct gcaacagtct gtgcttggaa ggcaaatcca
    25201 attagaacag aagctgctcc tacagcgtat ttacgaatag aaaaacgctg ttgtttttca
    25261 tgtttcattg caaaacctcc tgattgcatt gttatattga tagcgattat ataaatcaac
    25321 gcctttattt tatttcttat attaacgaga gtcaagagga gatgacaaaa aactataata
    25381 agtataaaaa aatataaaat ttaaacttaa gatttcagat tggtcgaaaa aatacatata
    25441 tatatctagt ataatttttg gttctatttc tataaaatat tccacaaatt atagaatctt
    25501 ccaaaaatag gtaagcgcta cctttttggt gtggtataat aagcatagaa aaagcccgag
    25561 cgattaggct caggctttct tcttagtgat cacggtcaca tgagatgaat ttaatcttgt
    25621 agtaatcaga tcgtttgtaa gtttcactgt attctaaaac ttggccagtt gattcgagtt
    25681 tggtgatttt agtttgtagg acagtaggga attgttcatc gactccgagg actgaagccg
    25741 catgttctgg agttggaaag actatttcgt tgatttcttc aaagtgttca tcattcatgt
    25801 gaatgtggta gtctaacttg aaacgattat agatagaact atagtattca aggtttggat
    25861 aatttgcgtt gatatattgt tctgggatgt aggatgtatg gtagatataa acgacaccgt
    25921 ttgattcgcg gatacgttca atcttgtagt agaattgatc gccgcgtaga cccaattttt
    25981 ccaagtaaac aagcttgttt ccgcgttcaa ttgaaagaac agttacctta tcatctttag
    26041 cattgaagag ttcaatatct gaaaactcta caagcttgtg tttgcgtgca cgtgaaacga
    26101 aggttccttt tccttgttgg cggacaatat agccatcttt ggcaaggtcg tttaaggcgc
    26161 gaacaactgt gatagagctg acatcgtaca ttgaaatgag ttctgcttca gtgtaaaatt
    26221 tatctccact gctaaactgc ccagagatga ttttattttt taattcgtct tttatgtatt
    26281 gatatttggg aattgccata tttttacctc tattttcctt ctccatagaa aattttacca
    26341 taaaagcgaa aaaaatagta gtcttttgaa taaaaaatta gaataatagt ttgaaaaatt
    26401 aagcgatata gggattgctc atattttatc aatgcattct atacaaaatt attttaggtc
    26461 ctatattccg aatttaaaga gcgtttgaaa tgggtctaaa aatgtttgaa actaattgaa
    26521 tgtgtgtata atagtaaaaa tgcagtaaat atcccgacaa tttctattga caattcaaac
    26581 agattggttt ataattaata taacaacaaa tgaaagcgca aactttcgcg gtcggaaggt
    26641 agttttatga cacgatttga gatacgagat gatttctatc tcgatggaaa atcatttaag
    26701 attttatctg gtgccattca ttattttagg attcctccag aggattggta tcattcgctc
    26761 tataacttga aggctcttgg ttttaatacg gtagagactt atgttgcttg gaatttacac
    26821 gagcctcgtg aaggtgagtt tcattttgaa ggtgatctgg atttagagaa atttctccaa
    26881 atagcgcagg atttgggtct ctacgcaatt gtgcgtccgt ctccatttat ctgtgcggaa
    26941 tgggaattcg gtggcttacc agcttggctc ttgaccaaga acatgcgaat tcgctcatcc
    27001 gacccagcat atatcgaggc agttggtcgc tactatgatc agttattgcc aagactggtg
    27061 cctcgtttgt tgaacaatgg tggcaatatt ctcatgatgc aggttgaaaa tgagtatggt
    27121 tcttacggag aagataaggc ttacctgaga gcgattcgac agctaatgga agagtgtggc
    27181 gtaacctgtc ccctctttac atcagatggt ccatggcgag ctactctgaa agctggaacc
    27241 ttaattgaag aggacctctt tgtaacagga aactttggtt ctaaggcacc ttacaacttt
    27301 tcgcagatgc aggaattctt tgatgaacat ggtaagaaat ggccactcat gtgtatggag
    27361 ttctgggatg gttggttcaa tcgctggaaa gaaccgatta tcacacggga tcctaaggaa
    27421 ttggcagatg cagttcgaga ggttttggaa caaggctcta tcaatcttta catgttccac
    27481 ggtggtacaa actttggttt catgaatggt tgctcagctc gaggaacttt ggacctgcca
    27541 caagttacat cttatgatta cgatgccctt ctggatgaag aaggaaatcc aactgctaaa
    27601 tatcttgcag tcaagaagat gatggcaaca catttttcag agtatccgca gttggaacca
    27661 ctctacaaag agagtatgga gttggatgct attccactag ttgaaaaagt ttctttgttt
    27721 gaaaccttag atagcttgtc aagtcctgta gaaagtctct atcctcaaaa gatggaggag
    27781 ctgggacaaa gttatggcta cctactttat cgaacagaaa caaactggga tgcagaagaa
    27841 gaaagacttc gtatcattga tggtcgagat agggcccagc tgtatgtcga tggtcagtgg
    27901 gttaaaactc aatatcagac agagattggg gaagatattt tttatcaagg taaaaagaaa
    27961 gggctatcta ggttagatat cttgatagaa aatatggggc gtgtcaacta tgggcataag
    28021 ttcttagcgg atacgcaacg taagggaatt cggacagggg tctgtaagga tctgcatttc
    28081 ttactaaact ggaaacacta tccactccca ctagacaatc ctgagaaaat tgatttttca
    28141 aaaggatgga ctcaaggaca accagccttt tacgcttatg actttacagt cgaagagcca
    28201 aaagatactt acctagactt gtctgagttt ggtaagggag ttgcctttgt caatgggcag
    28261 aatctaggac gtttttggaa cgttggccca actctctcac tttatatccc tcatagctat
    28321 ctcaaggaag gtgccaaccg tatcattatc tttgaaacag aaggtcaata taaagaagag
    28381 attcatttaa ctcgtaaacc tacactaaaa catataaagg gggaaaactt atgacaattg
    28441 taggatgccg tattgatgga cgtttgatcc acggacaagt agccaatctt tgggctggaa
    28501 aactaaatgt ttcacgcatt atggttgtag acgacgaagt tgtcaacaac gatattgaaa
    28561 agagtggttt gaaacttgcg acaccaccag gtgtgaaatt gagtattttg ccagttgaga
    28621 aagctgcagc caatattctt gctggtaaat acgatagcca acgtctcttt atcgtggctc
    28681 gtaaaccaga ccgcttcctt ggtttggtag aagcaggtgt accacttgaa acccttaatg
    28741 ttgggaatat gtctcaaaca ccagaaactc gttctattac acgttctatc aacgtagtag
    28801 acaaggatgt ggaagacttc cacaaactgg cagaaaaagg tgttaaactt actgctcaga
    28861 tggttccaaa tgatccaatt tcagactttt tgagcttatt aaaataggaa aaaaattttt
    28921 aggaggtcat tgttatgata caatggtggc aaattttact tctcactttg tactcagctt
    28981 atcaaatctg tgatgagttg acgatcgttt catctgcagg ttcccctgta tttgctggtt
    29041 tcattactgg tttaatcatg ggagatgtga ctactggttt acttatcggt ggtaacttgc
    29101 aactgttcgt tcttggggtt ggtactttcg gtggtgcttc tcgtatcgac gcaacttctg
    29161 gtgcggttct tgcgacagcc ttctctgttt cacaaggaat tgatgcaccg cttgccatta
    29221 ctacaatcgc tgtaccagta gcagctctct tgacttactt cgacgttctt ggtcgtatga
    29281 ctactacctt cttcgctcac cgtgtggatg ctgcaatcga acgctttgac tataaaggta
    29341 ttgaacgcaa ctacttgctt ggtgcgattc cgtgggctct atctcgtgcc cttccagtct
    29401 tctttgccct tgcttttggt ggtgcctttg tacaatcagt agtagacttc gttgaagcct
    29461 acaaatgggt tgcagatggc ttgacactcg caggacgtat gcttccaggt cttggatttg
    29521 caatcttgct tcgttacctt ccagttaaac gtaaccttca ctaccttgct atgggatttg
    29581 gtttgacagc tatgttgact gttctttact catatgtaac aggtcttggt ggcgctgttg
    29641 ctggtatcgt aggtactctt cctgctgaag ttgctgaaaa aattggtttc gtgaacaact
    29701 tcaaaggttt gtctatgatt ggtatttcta tcgtaggtat tttccttgca gtgcttcact
    29761 tcaaaaatag ccaaaaagta gctgtagcag caccttctac accatcagaa agtggggaaa
    29821 tcgaagatga cgaattctaa ttacaaactt acaaaagaag attttaatca aatcaacaaa
    29881 cgtagcttgt ttactttcca attaggttgg aactacgaac gtatgcaagc ttctggttac
    29941 ctttacatga tcttacctca gttgcgtaaa atgtatggtg atggaactcc tgaattgaaa
    30001 gaaatgatga aagttcatac tcaattcttc aatacttcgc cattcttcca taccattatc
    30061 gctggttttg accttgccat ggaagaaaaa gatggtgtag gttcaaaaga cgccgttaac
    30121 ggtatcaaga caggtttgat gggaccattc gctcctcttg gggatacaat ctttggttca
    30181 cttgtacctg ctatcatggg gtcagtcgca gcaactatgg ctatcgctgg ccaaccttgg
    30241 gggatcttcc tttggattgc agttgcagta gcgtatgaca tcttccgttg gaaacagttg
    30301 gaatttgctt acaaagaagg ggttaacctt atcaacaaca tgcaaagtac cttgacagct
    30361 ttgattgacg ctgcatctgt acttggtgtc ttcatgatgg gtgctcttgt agcaacagtg
    30421 attaactttg aaatttctta caagttgcca atcggtgaaa agatgattga tttccaagac
    30481 atcttgaacc aaatcttccc acgtttgctt ccagcaatct ttactgcctt tatcttctgg
    30541 ttgcttggta agaaaggtat gaactctact aaagctatcg gtattattat cgtacttgct
    30601 ttggctcttt ctgcccttgg tcactttgca cttggaatgt aattccttat gactaaatca
    30661 ttaattttgg tgagccatgg tcgcttctgt gaggagctta ggggtagcac agaaatgatt
    30721 atgggtccac aagacaacat ttacacagta gctcttcttc cagaagatgg cccagaagaa
    30781 tttactgcta aatttgaagc tgttattgaa ggattggatg atttcctagt ttttgcggat
    30841 cttctcggtg ggacaccttg taatgtggtg agtcgcttga tcatggaagg tcgtgatatt
    30901 gacctttacg cagggatgaa tcttccaatg gtgattgaat ttatcaatgc gagccttaca
    30961 ggcgcagatg cggactacaa gagccgtgct gcagaaagca ttgtgaaagt taatgacctg
    31021 ttagcgggct tcgatgatga cgaagatgaa taatactctt cgaaaatctc ttcaaactac
    31081 gtcaacgtcg ccttaccgta ggtatatgtt actgacttcg tcaatcttat ccggcaacct
    31141 caaagcagtg ctttgagcag cctgcggcta gtttcctaca gattttagtt ggaactcgat
    31201 tcaattcatg tgacaacgtg aaaatcgtta gagcatttta tatagaatat acatgggaat
    31261 ggagcttact cccattccca tatttaatag aaaaagagga actcaatgct acattataca
    31321 aaagaagact tgctcgaatt gggtgcagaa atcactacgc gtgaaatcta ccaacagcct
    31381 gatgtatgga gagaagcttt tgaattttat caagcaaaac gtgaagaaat tgcagccttc
    31441 ctacaagaaa tcgctgataa acatgactat attaaggtta tcttgacagg tgctgggact
    31501 tctgcttatg tgggagatac cttgctacct tattttaagg aagtctatga cgaacgcaaa
    31561 tggaatttca atgctattgc gacaacagat atcgttgcca atccagcaac ctatttgaaa
    31621 aaagatgtgg caactgtcct tgtgtctttt gctcgtagtg ggaactcgcc tgaaagtgtg
    31681 gcgactgttg atttggccaa atccttggtg gatgagcttt atcaagtgac gattacttgt
    31741 gcagcagatg gtaaattggc tcttcaagct cacggtgatg accgtaatct cttgctcttg
    31801 caaccagttg tctctaatga tgctggattt gccatgactt ctagctttac gtctatgatg
    31861 ttgacagctc tcttggtctt tgatcctaca gaatttgctg ttaagtctga acgttttgaa
    31921 gttgtatcta gtcttgcccg taaagtttta gacaaggcag aagatgtcaa agagctcgtt
    31981 gatttagact ttaaccgtgt catctatcta ggcgctggtc ctttctttgg acttgctcat
    32041 gaagctcagc tcaagatttt ggaattaact gctggtcaag ttgcgaccat gtatgaaagc
    32101 ccagttggct tccgtcacgg tccaaaatca cttatcaacg aagatacagt tgtcttggtc
    32161 tttggtacaa cgacagacta cactcgcaag tacgacttag acttggttcg tgaagttgct
    32221 ggtgaccaga ttgctcgtcg tgttgtgctt ttgagtgatc aagcttttgg tcttgaaaat
    32281 gtcaaagaag tggtccttgg ttgtggcggt gtcttgaatg atatttaccg tgtcttccct
    32341 tacatcgttt atgcccaact ctttgcccta ttgacttcac tcaaggtaga aaataaacca
    32401 gatacaccgt ctcctacagg tacagtaaac cgtgtagtac aaggtgtcat aattcacgaa
    32461 tatcaaaagt aagacagtgt ttatgaattc ttgacaagag gatttgtaaa ttatcagata
    32521 aaccatagat tgtcagtacg ctttctatgg tttgtttgct tgagagaaat agtaaaagga
    32581 gaacagaatg aaagcataca cagagcgtgt atttggaaat gttgagggcg aggatgtctt
    32641 ggcctatcga tttgagacag acggtggcta ccaacttgag gttatgactt atggtgcgac
    32701 catcttgcgc tatgtcgcac ctgacaaggc tggaaatttt gccaatgtta tcttgggatt
    32761 tgatgacttt gatagttatg taggcaatag tcccaagcat ggagcaagtg taggtcctgt
    32821 agcgggtcgt attgcaggtg cgacctttga gctcaatggt aagacctatg accttgaggt
    32881 taataatgct agcaactgta atcacagtgg ttcaactggt tgggattcca gcttgtttga
    32941 agttgaagaa gtaagcgatc atggcttgac tctctacaca gagcgtacat atgggacagg
    33001 agggttccct ggaaatctca agatttggat cagttatcac ttggaagaaa ctggtgccta
    33061 tgaaatcagc tacaaggtaa cgaccgatca ggatacgctg gtcaatccaa ccaaccacag
    33121 ctatttcaac ttgtctggtg atttcacgca gacgattgac cgtcatgtct tccaactaaa
    33181 cacagagggc atttactcaa tcgctcctga cggtgttcct gccaaaactc cagaagccaa
    33241 ccgtgatgtg gtcaaacaca tctacaatgg tgccttgttg aaggatatct ttgcagaaga
    33301 agatgagcaa atccagctgg catcaggttt ggatcatcca tttgcccttc ctgcaggcca
    33361 tgacaatgct ggattccttt atgaccaaaa ttcaggtcgc ttcctgcttt tcaagacaga
    33421 agctccttgc tttgtggtct acacagcaaa ctttgtggat gaaagtgtca tcataggagg
    33481 tcagccaatg ctacagcaca atgggattgc tcttgaagcg caagctttac cagatgccat
    33541 tcacagtgac cttaaaggcc aagtcattct taaagctggt caaaccttca ccagtaagac
    33601 acgttatgaa cttgttgtga aataaaaaag ctggtcaaaa agtctttaaa attaaaataa
    33661 cgcatattgt caggtgatga aaagtttgat aatatgcgtt ttattatgaa atgatttact
    33721 ttatcttatc ctgaaatggt gttatttttg agttatctgg cttgactttc ttgatggaaa
    33781 ttatataata gttgcaacaa taataattac aacgagaaaa gaggaccatt tatgacctat
    33841 gaatacaaga gtcacattta tttggcagag acagttttaa atgtaaagga tttggccagt
    33901 caaacagcct tttatcagca agttattggt ttagaaatct tatctcaaac tgagacagag
    33961 tccattctag gccttggtgg aaaagtcttg gtacagctga ttcaagcaca agagagcgga
    34021 gaagtgaggg aacattatgg tctttaccat ttggccattc tcttgcccac acgcaaggct
    34081 ttggctgatg tcttgaaaca cctgacagat ttacaaattc ctcttgtcgg cggtgcagac
    34141 catggttaca gtgaagctat ttacttggaa gatttggagg gaaatggcat tgaactctat
    34201 cgagataagc cagtttccac atgggatatt cgagaagatg gacgcattat cggagtgacg
    34261 gaggctcttg cggcgcagga catttatgag ttgggggaaa gagtagagtc ctttatcctg
    34321 gcagaaggta cgagaatggg gcatattcat ctttccgtca aggatagtcg aaagtccagc
    34381 cagttttatc aaaaggtgtt aggactagag gataaattca gtgtgcctgg cgctagttgg
    34441 attgcggctg gagattacca tcatcattta gcagttaacg aatggggagg aaaaggtctg
    34501 gcttcgcgta agcaaggctt accaggttta gcctactatg tcatcgaagt cgcacataaa
    34561 gaagaactgt taacgattgc ccaacgagca caagaagttg acgcaccaat caaatggatg
    34621 acatcgagcc aattggaaat cacagactca gatggcatcg tgacccgtat tcgtttagca
    34681 aggtaaaatt aggaatttct aataagttat aagtattgct agtttgcttt ttgaacggtc
    34741 tttggtaaca gaactgcgtg agctggatgg gtgagaattt tgacaaagaa gctgattaga
    34801 gatataatga agaaaaatcg agcaaggaaa aagaaatgac aaattcaaag tatattactc
    34861 gtttgaaacg ttcagagggc cagttgcgtg ggattcaaaa gatgattgaa ggagatcgtg
    34921 acgcaactga cagcagtgaa atctagtgta gagcgcgtga ttgagatgat aattaccgaa
    34981 aatcttactg aatgtatcaa tcagccccta gatgattctg aagctcaaaa ggaacgccta
    35041 gaaaaggcta tctgatactt gattaaacgg aaataaatga atgttttgag acgatatgtg
    35101 caaaggtcta ttaactatta gaatagttta atgtgagtca aaagaagttg taaaaaatct
    35161 ttaaaattaa aaaaacgcat agtattaggt attgaaatgt actgcccccc aaaagttaga
    35221 ttttttctgt ctaacttttg gggggcagta cataaaaacc ttgatagtat gtgttttatt
    35281 gtggggagat ttatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta
    35341 gatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagctgac
    35401 ttcgtcagtt ccatccacaa ccttaaaaca gtgttttgag ctgacttcgt cagttccatc
    35461 cacaacctta aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca
    35521 gtgttttgag cagcctgcgg ctaacttcct agtttgcact ttgattttca ttgagtatta
    35581 cttcatcttt tcctgaaatt gagtttttgc ccagctcctc ttgattattc tacttgaccg
    35641 ggccaagcat tcataccacc ttctacgttg gtaacggtga ggccttggga gctgagaaat
    35701 tggcaggtag atgcagagcg gactcctccg tgacaaatga catagtattc atggtcaggt
    35761 ttgagttctt tgtagccttg ctctaaggta tttatggaag atttttgggt cctgcttgga
    35821 attcatgtgc ttcacggaca tcgataagtt ctagattttc attttggtat tttccataaa
    35881 agtcagccat gctgatacta gtttccatat tctactcctt ctgggttaac cattttgtat
    35941 agtgaataag cgccgtcaag gttttgggcg gtaaatcctg cttgcttgag gataggctct
    36001 gcgatatagc tgcgcaaacc actgtggcag ctgacgatgt aggcttgttt tttgtccagt
    36061 tcatcagctt cctccttgac actttgtcag tttttgatac aatagtacaa aattagagga
    36121 ggcaggctat gattcagaaa catgcgattc ctattttaga gtttgatgac aatcctcagg
    36181 cggttatcat gcccaatcac gaggggctgg acttgcagtt gccaaagaag tgtgtttatg
    36241 catttttagg tgaggagatt gaccgctatg caagggaagt aggggcggat tgtgtcggcg
    36301 aattcgtttc tgctaccaag acctatccag tctatgtcat caactacaag ggtgaggagg
    36361 tctgtctggc tcaggctcct gttggctccg ctccagcagc ccagtttatg gattggttga
    36421 ttggctatgg tgtggagcag attatctcta ctgggacctg tggtgtccta gctgatatag
    36481 aggaaaatgc ctttctagtc cctgttcgcg ctttgcgaga tgagggagcc agttaccact
    36541 atgtggcacc ttgtcgttat atggaaatgc agccagaggc tattgctgct attgagcgag
    36601 ttttggatga tagagggatt ccttatgaag aagtcatgac ctggacgaca gacggttttt
    36661 accgagaaac ggctgaaaag gtggcttatc gtaaggaaga aggctgtgct gttgtggaga
    36721 tggagtgttc tgctcttgcg gcagtagctc aattgcgtgg ggttctctgg ggtgaattgt
    36781 tgttcacagc agattctcta gcggacttgg accagtacga cagtcgtgac tggggctcgg
    36841 aagcttttaa taaggcgcta gaactgagtt tagcaagtgt tcaccacctt tagttgtact
    36901 ggcaaaggat ttgttttatc ataaaatgtc tagctcatac ttttcaaaaa tatgtttaaa
    36961 cgaggtcacc ttcctcttgt cctaggcatg ttgaggttgg gaaaaatctt taaaatcaga
    37021 aaaacgtatc atatcaggtg atgaaaattt tgatactatg cgttttatgt tggtaagatt
    37081 tagagtgaga tgaaatgata ctcttcgaaa atctcttcaa accaggtcag cttcaccttg
    37141 ccgtatagat gttactgact tcgtcagttc tatctgcaac ctcaaaacag tgttttgagc
    37201 tgacttcgtc agttctattt gcaacctcaa aacagtgttt tgagcaacct gtgactagct
    37261 ttctaattga tgccttggtt ctcattgcct ataatcaaaa agagaaattt tctcctgaaa
    37321 agcatataga gtagctggcg ttaaaagctc ctgtctcgct tttttgacct atagtcacat
    37381 ctatcaagta ttgttcttgc ctaagctatc aataaaaagg tggcattttt taggcttggt
    37441 gttagtagat tttgccttat cctatctaag tcatttcgaa ctttttatgg tacaatggaa
    37501 acatgttatt caaattatct aaggaaaaaa tagagctagg cttatctcgt ttatcgccag
    37561 cccgtcgtat ttttttgagt tttgccttgg tcattttact aggctctctt cttttgagct
    37621 tgccctttgt ccaagttgaa agctcacgag cgacttattt tgatcatctt ttcactgctg
    37681 tctctgcagt ctgtgtgaca ggtctctcaa cccttccagt agctcacacc tataatatat
    37741 ggggccaaat aatctgtttg cttttgattc agatcggtgg tctagggctc atgaccttta
    37801 ttggggtttt ctatatccag agcaagcaaa agcttagtct tcgtagccgt gcaactattc
    37861 aggatagttt tagttatgga gaaactcgat ctttgagaaa gtttgtctat tctatttttc
    37921 tcacgacctt tttggttgag agcttaggag ctattttgct tagttttcgc cttattcctc
    37981 aacttggctg gggacgtggt ctttttagtt ccatttttct agcgatctca gccttctgta
    38041 atgccggttt tgataattta gggagcacca gtttatttgc ttttcagacc gatttactgg
    38101 tcaatctggt gattgcaggc ttgattatta caggcggcct tggttttatg gtctggtttg
    38161 atttggctgg tcatgtagga agaaagaaaa aaggacgtct gcactttcat acgaagcttg
    38221 tactattgtt gactataggt ttgttgttat ttggaacggc aactactctc tttcttgagt
    38281 ggaacaatgc tggaacgatt ggcaatctcc ctgttgccga taaggtttta gttagctttt
    38341 ttcaaacagt gacgatgcga acagctggct tttctacgat agattatact caggctcatc
    38401 ctgtgactct tttaatttat atcttacaga tgtttctagg tggggcacct ggaggaacag
    38461 ctgggggact caagattacg acattttttg tcctcttggt ctttgcacga agtgagcttc
    38521 taggcttgcc tcatgccaat gttgcgagac gaacgattgc gccgcgaacg gttcaaaaat
    38581 cctttagtgt ctttattatc tttttgatga gcttcttgat aggattgatt ctgctaggga
    38641 taacagccaa aggcaatcct ccctttatcc acctcatatt tgaaaccatt tcagctctta
    38701 gtacagttgg tgtaacggca aatctgactc ctgaccttgg gaaattggct ctcagtgtta
    38761 tcatgccact tatgtttatg ggacgaattg gtcccttgac cttgtttgtt agcttggcag
    38821 attaccatcc agaaaagaaa gatatgattc actatatgaa agcagatatt agtattggtt
    38881 aagaaaggaa agagcatgtc agatcgtacg attggaattt tgggcttggg aatttttggg
    38941 agcagtgtcc tagctgccct agccaagcag gatatgaata ttatcgctat tgatgaccac
    39001 gcagagcgca tcaatcagtt tgagccagtt ttggcgcgtg gagtgattgg tgacatcaca
    39061 gatgaagaat tattgagatc agcagggatt gatacctgcg ataccgttgt agtcgcgaca
    39121 ggtgaaaatc tggagtcgag tgtgcttgcg gttatgcact gtaagagttt gggggtaccg
    39181 actgttattg ctaaggtcaa aagtcagacc gctaagaaag tgctagaaaa gattggagct
    39241 gactcggtta tctcgccaga gtatgaaatg gggcagtctc tagcacagac cattcttttc
    39301 cataatagtg ttgatgtctt tcagttggat aaaaatgtgt ctatcgtgga gatgaaaatt
    39361 cctcagtctt gggcaggtca aagtctgagt aaattagacc tccgtggcaa atacaatctg
    39421 aatattttgg gtttccgaga gcaggaaaat tccccattgg atgttgaatt tggaccagat
    39481 gacctcttga aagcagatac ctatattttg gcagtcatca acaaccagta tttggatacc
    39541 ctagtagcat tgaattcgta aagagggatg acccctcttt tttgatgcct aagatggcaa
    39601 atagagacag aagccccttg tcttctagta aaagttcttc aaaggctgga ctttatggta
    39661 aaatagaaag aagtgacaag agagagtaat actcaatgaa aatcaaagat caaactagga
    39721 aactagctgt gggctgctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
    39781 gctcaaaaca ctgttttgag gttgcagata gaactgacga agtcagtaac atctatacgg
    39841 caaggcgacg ttgacgcggt ttgaagagat tttcgaagag tataagaaaa aatcagtccc
    39901 ctaaaggagc agattatgaa gttattgtct atcgcaattt ctagctataa tgcagcagcc
    39961 tatcttcatt actgtgtgga gtcgctagtg attggtggtg agcaagttgg gattttgatt
    40021 atcaatgacg ggtctcagga tcagactcag gaaatcgctg agtgtttagc tagcaagtat
    40081 cctaatatcg ttagagccat ctatcaggaa aataaatgcc atggcggtgc ggtcaatcgt
    40141 ggcttggcag aggcttctgg gcgctatttt aaagtagttg acagtgatga ctgggtggat
    40201 cctcgtgcct acttgaaaat tcttgaaacc ttgcaggaac ttgagagcaa aggtcaagag
    40261 gtggatgtct ttgtgaccaa ttttgtctat gaaaaggaag ggcagtctcg taagaagagt
    40321 atgagttacg attcagtctt gcctgttcgg cagatttttg gctgggacca ggtcggaaat
    40381 ttctccaaag gccagtatac catgatgcac tcgctgattt atcggacaga tttgttgcgt
    40441 gctagccagt tctaactgcc tgaacatact ttttatgtcg ataatctctt tgtctttacg
    40501 ccccttcagc aggtcaagac catgtactat ctgcctgtcg atttctatcg ttatttgatt
    40561 gggcgtgagg accagtctgt caatgagcaa gtgatgatta agtgcattga ccagcaactc
    40621 aaggtcaatc gactcttgat agaccaactt gatttgtccc aagtgagtca tcccaaaatg
    40681 cgagaatatc tgctgaatca tattgaactc acgacggtga tttccagtac cctgctcaac
    40741 cgatctggaa cagcggagca tctggcaaaa aaacgccaat tgtggaccta tattcagcag
    40801 aaaaatccag aagtctttca ggctattcgt aagaccatgt tgagccgttt gaccaaacat
    40861 tctgtcttgc cagatcgcaa actgtccaat gtcgtctatc aaatcaccaa atctgtttat
    40921 ggatttaatt aatataagtg ttttataaga gggatttaag aaaaatttta actttttctt
    40981 agtccttttt aatttcagga gattatacta gagtcatcaa ataaagaaag actctaagga
    41041 gaatcctatg aaattcaatc caaatcaaag atatactcgt tggtctattc gccgtctcag
    41101 tgtcggtgtt gcctcagttg ttgtggctag tggcttcttt gtcctagttg gtcagccaag
    41161 ttctgtacgt gccgatgggc tcaatccaac cccaggtcaa gtcttacctg aagagacatc
    41221 gggaacgaaa gagggtgact tatcagaaaa accaggagac accgttctca ctcaagcgaa
    41281 acctgagggc gttactggaa atacgaattc acttccgaca cctacagaaa gaactgaagt
    41341 gagcgaggaa acaagccctt ctagtctgga tacacttttt gaaaaagatg aagaagctca
    41401 aaaaaatcca gagctaacag atgtcttaaa agaaactgta gatacagctg atgtggatgg
    41461 gacacaagca agtccagcag aaactactcc tgaacaagta aaaggtggag tgaaagaaaa
    41521 tacaaaagac agcatcgatg ttcctgctgc ttatcttgaa aaagctgaag ggaaaggtcc
    41581 tttcactgcc ggtgtaaacc aagtaattcc ttatgaacta ttcgctggtg atggtatgtt
    41641 aactcgtcta ttactaaaag cttcggataa tgctccttgg tctgacaatg gtactgctaa
    41701 aaatcctgct ttacctcctc ttgaaggatt aacaaaaggg aaatacttct atgaagtaga
    41761 cttaaatggc aatactgttg gtaaacaagg tcaagcttta attgatcaac ttcgcgctaa
    41821 tggtactcaa acttataaag ctactgttaa agtttacgga aataaagacg gtaaagctga
    41881 cttgactaat ctagttgcta ctaaaaatgt agacatcaac atcaatggat tagttgctaa
    41941 agaaacagtt caaaaagccg ttgcagacaa cgttaaggac agtatcgatg ttccagcagc
    42001 ctacctagaa aa
//
LOCUS       DAVHSL010000014        39067 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000014 DAVHSL010000000
VERSION     DAVHSL010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39067
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.014"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(386..1246)
                     /locus_tag="VVR39_000753"
     CDS             complement(386..1246)
                     /locus_tag="VVR39_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU6030281.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1262..2539)
                     /locus_tag="VVR39_000754"
     CDS             complement(1262..2539)
                     /locus_tag="VVR39_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6030282.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATTINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2532..3083)
                     /locus_tag="VVR39_000755"
     CDS             complement(2532..3083)
                     /locus_tag="VVR39_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030283.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWAQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3099..4358)
                     /locus_tag="VVR39_000756"
     CDS             complement(3099..4358)
                     /locus_tag="VVR39_000756"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6030284.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5445..5603)
                     /locus_tag="VVR39_000757"
     CDS             complement(5445..5603)
                     /locus_tag="VVR39_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030285.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5613..6923)
                     /gene="obgE"
                     /locus_tag="VVR39_000758"
     CDS             complement(5613..6923)
                     /gene="obgE"
                     /locus_tag="VVR39_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU6030286.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(6987..7121)
                     /locus_tag="VVR39_000759"
     CDS             complement(6987..7121)
                     /locus_tag="VVR39_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU6030287.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7180..7356)
                     /locus_tag="VVR39_000760"
     CDS             complement(7180..7356)
                     /locus_tag="VVR39_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6030288.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7387..8712)
                     /locus_tag="VVR39_000761"
     CDS             complement(7387..8712)
                     /locus_tag="VVR39_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6030289.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8728..9771)
                     /gene="cpoA"
                     /locus_tag="VVR39_000762"
     CDS             complement(8728..9771)
                     /gene="cpoA"
                     /locus_tag="VVR39_000762"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU6030290.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9886..10215)
                     /locus_tag="VVR39_000763"
     CDS             complement(9886..10215)
                     /locus_tag="VVR39_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6030291.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10229..11338)
                     /gene="rpoD"
                     /locus_tag="VVR39_000764"
     CDS             complement(10229..11338)
                     /gene="rpoD"
                     /locus_tag="VVR39_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU6030292.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11341..13101)
                     /gene="dnaG"
                     /locus_tag="VVR39_000765"
     CDS             complement(11341..13101)
                     /gene="dnaG"
                     /locus_tag="VVR39_000765"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6030293.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPSE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDDNQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13191..13949)
                     /locus_tag="VVR39_000766"
     CDS             complement(13191..13949)
                     /locus_tag="VVR39_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030294.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13946..14812)
                     /locus_tag="VVR39_000767"
     CDS             complement(13946..14812)
                     /locus_tag="VVR39_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030295.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14881..15885)
                     /locus_tag="VVR39_000768"
     CDS             complement(14881..15885)
                     /locus_tag="VVR39_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6030296.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(15998..16215)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16298..18994)
                     /gene="ppc"
                     /locus_tag="VVR39_000769"
     CDS             complement(16298..18994)
                     /gene="ppc"
                     /locus_tag="VVR39_000769"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU6030297.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19014..20243)
                     /locus_tag="VVR39_000770"
     CDS             complement(19014..20243)
                     /locus_tag="VVR39_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6030298.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20371..20624)
                     /locus_tag="VVR39_000771"
                     /pseudo
     CDS             complement(20371..20624)
                     /locus_tag="VVR39_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(20800..21052)
                     /locus_tag="VVR39_000772"
                     /pseudo
     CDS             complement(20800..21052)
                     /locus_tag="VVR39_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            complement(21334..21921)
                     /locus_tag="VVR39_000773"
     CDS             complement(21334..21921)
                     /locus_tag="VVR39_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU6030299.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYFLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(22000..22428)
                     /locus_tag="VVR39_000774"
     CDS             complement(22000..22428)
                     /locus_tag="VVR39_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030300.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            complement(22691..22813)
                     /locus_tag="VVR39_000775"
                     /pseudo
     CDS             complement(22691..22813)
                     /locus_tag="VVR39_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(22911..23147)
                     /locus_tag="VVR39_000776"
     CDS             complement(22911..23147)
                     /locus_tag="VVR39_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030301.1"
                     /translation="MKIINGICRYIFDSKGFATIEVEIFLDSGDTGIGAAPRGSTTGH
                     YDIQYNEYYPRGNNFSPIPDGNIEFFRLYNICSG"
     gene            complement(23212..24175)
                     /locus_tag="VVR39_000777"
                     /pseudo
     CDS             complement(23212..24175)
                     /locus_tag="VVR39_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974692.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
     gene            complement(24441..26275)
                     /locus_tag="VVR39_000778"
                     /pseudo
     CDS             complement(24441..26275)
                     /locus_tag="VVR39_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(26262..26627)
                     /locus_tag="VVR39_000779"
     CDS             complement(26262..26627)
                     /locus_tag="VVR39_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU6030302.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIDKRHCQNFSVYTRKVLLN
                     PNMAFVTINTDTYEQLVFELRRIGNNINQIVRAINQSHLISQDQLQELSKGISELITG
                     VEKDFQVEVNRLKEFYGSH"
     gene            complement(26637..26996)
                     /locus_tag="VVR39_000780"
     CDS             complement(26637..26996)
                     /locus_tag="VVR39_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030303.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(27828..28985)
                     /locus_tag="VVR39_000781"
     CDS             complement(27828..28985)
                     /locus_tag="VVR39_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030304.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHLLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LLGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLNFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKNSFKHKMSIYETALSE"
     gene            complement(29013..29774)
                     /locus_tag="VVR39_000782"
     CDS             complement(29013..29774)
                     /locus_tag="VVR39_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU6030305.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKETAQLLKSKGYEVQLALIATKSELSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEKRLNELLEK"
     gene            complement(29774..30250)
                     /locus_tag="VVR39_000783"
     CDS             complement(29774..30250)
                     /locus_tag="VVR39_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6030306.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(30695..31150)
                     /locus_tag="VVR39_000784"
     CDS             complement(30695..31150)
                     /locus_tag="VVR39_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030307.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKNQQGNTMESYF"
     gene            complement(31425..33164)
                     /locus_tag="VVR39_000785"
     CDS             complement(31425..33164)
                     /locus_tag="VVR39_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU6030308.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFAHIQYLFEIIDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAIMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            complement(33327..34211)
                     /locus_tag="VVR39_000786"
     CDS             complement(33327..34211)
                     /locus_tag="VVR39_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU6030309.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASRERYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKFLE
                     INQDIDDAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(34323..35177)
                     /locus_tag="VVR39_000787"
     CDS             complement(34323..35177)
                     /locus_tag="VVR39_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU6030310.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(35235..35993)
                     /locus_tag="VVR39_000788"
     CDS             complement(35235..35993)
                     /locus_tag="VVR39_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6030311.1"
                     /translation="MVVYIRQSKLLSEVSINKYNAQVGAYLQGEEVILYQSFSKIKEL
                     TSEDIDVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(36055..36243)
                     /locus_tag="VVR39_000789"
     CDS             complement(36055..36243)
                     /locus_tag="VVR39_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU6030312.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(36565..37131)
                     /locus_tag="VVR39_000790"
     CDS             complement(36565..37131)
                     /locus_tag="VVR39_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030313.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESNGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHVDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(37399..39063)
                     /locus_tag="VVR39_000791"
                     /pseudo
     CDS             complement(37399..39063)
                     /locus_tag="VVR39_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270433.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT        11637 a         8423 c         6082 g        12925 t
ORIGIN      
        1 attcatagaa ctactatacc atattttgtt tcgcaggaag tataatataa aaaagtaaat
       61 ttaagattgg caatacgaac gttaaataga attccatttc tctttttaga atcaaaacga
      121 caatattgtg gaatctctac aggaacaata gactgcgaca ctaaaatatc ctcccttagt
      181 tttactttac taatagtata taggaggaga gccctgaatc ctagaccctt tgttatgatg
      241 cgcttacaaa cagagttgga aaaaatctta aaagcagaaa aacgcatgat atcagcccct
      301 aacacttgat acaatgcatt ttattatgaa aagatctact ggatttttta tcaaaataaa
      361 cttccagtag tcttttcact ttttattaat aagttccttc ttcaccttgg ctagtcaaga
      421 taacaggtcc atctttcgta atgacaaatt ggtgttcata ctgacatgac aatccaccgt
      481 caatggtctt atgcgcccaa ccagttttca tatctgtatc aatttcccaa tcgcctgtat
      541 tgatcattgg ttcaatggtt aagaccattc cttcacgaag acggagtcca cgacctgcaa
      601 taccatagtt aggaaccatt ggttcttcgt gcatagttgg gccaacacca tgaccaacca
      661 aatcacgcac tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc gcaccgatat
      721 caccgatacg atttccaaca acagcttgct caataccctt gtacatagct tctttggtta
      781 catccatcaa gtttttgact tcttcggacg gtgtaccaac agcataagcc caacatgagt
      841 ctgctaaacc accagaatag ctctgagtgt attttttcat ttgttcaaca ttgttgaagt
      901 ttaattttga gacattcagg tcggatttag caatgggacc tcccaaaacc atatcaactt
      961 tgagcaaatc accatctttc aagatataat gacgagggaa agcgtgagcc acttcatcgt
     1021 taagagagca acaggtagca taaggatagt ccatcatggc accgtcaacc ccaatctgaa
     1081 gtggaaggaa attttcttct ttacaacgac ggcggacata ttcttcaact tcccacatat
     1141 ctacgcctgg tttaatcaaa tcacgtaagc ctatatgaat acttgctaga aaatcaccag
     1201 ccttgtccat agcttcgatt tcacgagctg attttaatgt tatcatcttt tctcctagtt
     1261 tctaattaat tttaacagtc acatttgctt ttgaaacaat ctggtgacca tgataaatat
     1321 cgtaatcaat tatagctgac cgtctcgtat gatgaataat ccgtgcctga atgcgcaata
     1381 tatcatctat ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata atgagattgc
     1441 gaccactatt aacaactaaa tcttgggtca tgtgggtcag aatttctgcc aatacaccat
     1501 tagccaaaac tccatttttt tctagcataa agggttccac tgtaatgact acttcatcat
     1561 ggtgataaga gagcttttgt ccaatctgct cagaaaaagt tggtagagcc gaaacttggg
     1621 aacggctcat cttctccatg acatctcgtc gcgtcacaac gccaagcaaa gtttgattgc
     1681 ttcgaacaac tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc acattggcaa
     1741 tatttgtcga taatccaacc aaaaatagac tacgagacat aaccttatca attgtcgtgc
     1801 ttggtgattt atcaccagcg tctctcatgg ttacaacgcc aacaacgacc tgatgttgat
     1861 tgataacagg gaaacggctg ctacgattct tacgaaccaa gtccaaataa tctttaactg
     1921 tatctgtctc tctcagaaaa ccatactcat gactagggcg ataaagtttc tcaactgtca
     1981 gaatatcagt cttgatttgg acatttgaca aggctttatt gatcgtggtc gcgacggtaa
     2041 aggtatcatg cttacttctt agaacaggaa tccctttttg attggccagt ttaagcacat
     2101 catcatgaac ctgaaatccc cctgtaacca gaactgcatt ttcattttcc aaggctagca
     2161 actgaatacg ggttcggtct ccgacaatca agagcccccc atcatgaagg taagacaaga
     2221 tattttgttc agtcatggca ccaattgaaa acttgctaaa ttctctctct aaaccttctt
     2281 gcccagccag aacctcagaa gaagtcactt ctgcaatttc agcaaacgtt aatctctcta
     2341 tagcaacttt ctgggattta acacgaattg ttccacttct aggacgggtc tccacaattc
     2401 cacggttttc agcttcttta atagcccgat aggctgttcc atcactaact cctagatgat
     2461 tcgaaatgct acgaacactg acccttttac ctactggtaa ttcctccaaa tagcttagaa
     2521 tttcctgatg cttactcatt gaactctcct tttacatacc gaaattcaag ataatcccgc
     2581 atttttcttg tgtaacgatc acttccctta aactgacgga acaaactaaa tccagactta
     2641 agagcaactc tttggctagc ttcattttca aggtgggtaa tgatagataa ttgttttaag
     2701 ccaaattcct caaaagaaag ctgacaaatt tttctaacaa cctctgtcat aaatccttgc
     2761 gcccaagcat cttttctcaa aaaatagcca agctcagctt cttttttgat ttcatctaac
     2821 ttctcaaatt taatagaacc aatcatttgt tgatttttct ggtcacaaat tgcccacact
     2881 cccaaagggg acttcataaa gtaattggcc agtgcatatt gactttcttc cagacttgcc
     2941 tgcgttggga aaataaattg aagattttct ggatttgaag ctatctcgcg gaagtcctga
     3001 ctatcactaa aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa agaaaacatt
     3061 gctaatttgg tccaaatatt cataaacacc tctacggttt aatcctcaac aagtctaata
     3121 tccgctccta aattacgtaa tttttcgata atatcagaat aaccacgtaa gataaactcg
     3181 atattggtaa tttcagtttt accttcagcc ataagcccag caatgactag tgcagcccca
     3241 gctcttaagt cggtcgcttt aacactggcc ccacgtaaat cacgtccacc cgtgtacaaa
     3301 atatgaccat ttgttgtcga aatatccgca tccatctttg ctagttcaaa aacatgattt
     3361 acacgttttt cgtaaatcgt atcgacaatt gtaccacgac cattcgctct tagtaaaaga
     3421 ggggtaagcg gttgttgcaa atcagttgca aagcctgggt aaggagctgt cttaatattg
     3481 attgctttca aattagactg ttcctcgaca aaaatgctgt cttcagatac agtcattctc
     3541 actcccattt cttccaactt agcaataaac ccttccaggt gttcgtaaag aacattattt
     3601 atacgaattc ctttaccaac tgcagcagct aaagatatat atgttccagc ttcaatgcgg
     3661 tctggaatca cctgatgacg tgtcccatgt aatctttcaa caccatcaat aatgatgata
     3721 ttagttcctg ccccacggat atgggcaccc atattattca agagagtagc tacatcaata
     3781 atctcaggtt cacgggctgc attttcaata atagtacgac catttgcttt aaccgcagca
     3841 atcatcgtat taatcgttgc tcccacacta accgtatcca tgtaaatact tgcaccatga
     3901 agtcctgtat ctttagcaga taacttcatg ttatctccct cgtagctagc agtggcaccc
     3961 atagcttcaa acgccttaag gtgtaagtca atcggacgag gaccaagatc acatcctccc
     4021 ggtagaccaa ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa ataataagat
     4081 gcacgaagac tgttaatttt accataaggc attggaatat tttgaacacc tcttggatca
     4141 atctccaaga catcgtcata acgcttaaca gtagctccca tcaattccat gatttcgaca
     4201 agactggcta catccgaaat atctggaaca caatccaaag tcaccacatc atcagccaat
     4261 ataatagctg gaattaaggc cacaacacta tttttagcac cactaatagt aatttcacct
     4321 tgcagtggta atccaccatt gataacaatt tttctcattc taagttttca atactctttc
     4381 aagatttcta ataaggtctt caaaataaag tatatcataa atttatcctt ttttccatcc
     4441 ttttcaattt tattggataa atcagagttg acgagttagt aactgaatta ctaatactca
     4501 ataaaaatca aagatcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag
     4561 gttgtagatg gaactgacgt agtcagtatc ctacacgtac ggcaaggcga tattgacgtg
     4621 atttgaagag attttcgaag agtataatct ttctcgaatc gctattgccc cttttttatc
     4681 ccctgaaacc gagtaggagc taagactaga tctcttatct aaatatcgga atacggctgt
     4741 tcaactaaat tttagcaaga acctctcccc cttctctcag ttcacagaag cgttttatac
     4801 ataccgtcct atatttcatg aacaagacgt tttcaggcta gcatcctatc agacaatcta
     4861 ttttaaagat aaccgtgact caggatcact tctatctgtc gttttctctt tatagtgata
     4921 gacctcacgg gataagtcgt acatctttcc tcgtgtatac aagatatgag gacgttaaaa
     4981 ggttacagtg aaaatagaaa atcttagtac gaattcaatt actctcgtga tttacgcata
     5041 taggttacga ctaccttttt ggactttaga gtttgaggcc ctcttatccg ctatatacgc
     5101 cttattatca cgttcctgtt cgtagagcca cgatttcgct atcccttctt ctgacaattc
     5161 ttatttccag cgtcagactt aaaacggtct atccccagac cattttaatc cgctacctca
     5221 cgatagtcag gcttgggaat cgctatttga ctcgccgaga actttgacat cagatatact
     5281 ataacaaatt gaaataagaa tcaaacaatt taattttgaa attcaaatca atttataaca
     5341 atattttaga agatatgctg tgctattcca gattcagttc gctatacatg cccgtcgtac
     5401 cacaaaatcc cgtgtctgat gaggcacggg attttttagc ttctttactg agatggattt
     5461 tcctttttag ttcgtgccaa tctcaaggca cgatttggat ttagacgatt aaatagttct
     5521 tccaatttct tttcattcca aacgtctgcg gcggaaacaa aattaccatc cgcatctcgg
     5581 aaagatatcg gtttatctcc cataccagtc tcctagtcta caaattcaaa ctcaaattta
     5641 ccaatgcgga ccaaatcccc atctttagct ccacgcgcac gaagggcttc atcaaccccc
     5701 ataccacgaa gctgacgggc aaatttcatg acagattcat cacgatcaaa gttggtcata
     5761 ttaaagagtt tcatgagttt ttcaccagaa agtacccatg tcgcatcgtc atcacgacta
     5821 atttcaaagg ctttttcttc ttcgtcaaat ccatagtaag cttcttcttc catatcggac
     5881 tcgtcgtaga gcaaaaattc tggtgtctta tctaacaatt cagctgtagc atctaaaagt
     5941 gttgccagac cttgcttggt caatccagaa attgggaaga tagctggtaa ctcttcaaat
     6001 tcatcataat tttcagccaa ttttttctta aattcttcaa gattttcctg actctcaggc
     6061 atgtccatct tattagctac aataatctgt ggacgctcca tgaggcgaag attgtaagac
     6121 tccagctctt tattgatagc taggtaatcc tcatatggat cacggccttc gctagctgac
     6181 atatcaatga tgtgaaggat aacacgtgta cgctcgatgt gacggaggaa ctgagttccc
     6241 aaaccaacac cttgactagc cccttcaatc aaacctggca agtcggctac tgcaaaggat
     6301 tcacctgatt gggtgcgaac catacctaaa tttggtacaa tagtggtaaa gtggtaggca
     6361 ccaattttag gcttagctga ggtaataaca cttaaaagtg ttgacttccc tacagatggg
     6421 aatcctacta aaccgacatc tgccaagatt tttagttcca attgtaactc acgttcctga
     6481 cctggttctc cattttcaga gatttccggt gcaggatttt ttggtgtcgc gaaacgaata
     6541 tttccacgtc caccacgacc accgtgggca acgataaatt cttgcccatg ttcaatcaaa
     6601 tctgttaaaa ccttgccagt ctccgcatca cgaacagtcg taccttgtgg tactcgaact
     6661 ctaaggtcct cagcaccacg accatgcatc cctttggtca tccctttttc accagaatca
     6721 gccttgaaat gacgattgta gcggaaatcc atcaaggtac gtagtccttc gtctacaacg
     6781 aagaccacat tgcctccacg accaccatca ccaccccaag ggcctccatt agggacatat
     6841 ttttcacgac gaaaggcaac cataccatcg ccaccattac cagccttgac cttaatctta
     6901 gctgtatcta aaaacatact cattatttct tctcacttta aaaaagggct gggaaatccc
     6961 agtcactaaa ttttcttgaa tctattttat agattactga gggcaccaat tgcagttgca
     7021 aaaattccca ataaacttgc tactagcatg ataatcacga taaacaaggt tattttctca
     7081 aacatagttt ttttacgatt tccattatct ccaaatgcca tttttctctc cttcgttaca
     7141 ttctattttc tattatctta gcatgaattg agctagtttt caatagtcag ttgctactgg
     7201 tgcgataatc cataaaataa tgtaagctac aattccagct ccgtaacagc aagtaagaac
     7261 accccaaatg acttgaacga tagtcggatc catatccaga taatgggcca ccccagcaca
     7321 aacacccgca atctttttat cacgaccgct tctcattaat tgtttttttc atagctgttc
     7381 ctctttctat tcttcatggt ctttccaata gtctctcata ctgatcaact gtgtttttga
     7441 agccttcaac atgcgtctag atccttttac aggtacagca accacctgtt gctgaagata
     7501 caaaactgtc ttaaagatac gctgactgac cgtatcatct ttagccaaat ctttctggaa
     7561 gttatttgaa ataatggcat ccagataaaa ctcatgcact cgtttcccaa agttctcagc
     7621 tgaaatctca tacaatttct ctgataaggt atgctcgttc atgtctggtg ttgcaatcag
     7681 ggcttccaaa atagcaccag ccaaatcatg ttctccatag tacaaggttc caaacatttt
     7741 atcactgatg aggttgttca aataaggatt tccgtgagca atgacaggtg ttccactggc
     7801 taagctttcc aagtaggtca aaccttgcgt ttcgcttgtc gatgccgaaa tgaagaaatc
     7861 cgccgcttta tagtaaagag ccgtctcact aggagcaatc atccctgtaa agatgactga
     7921 gtcttgaatc tctaggttct gggcttgctc tttgaggtca ttcagataag ggccatcccc
     7981 agctactacc agtttaacct tgtcttcctc tttcagaaca tcagcaaagg ctgctaaaac
     8041 tgcttgaata tttttttcat aggagattct cgaaagacta agcaacgtct tttcaccatc
     8101 ttgaatccct agtttactac gcagttcttt caaattttcc tgcttgattt ccggacgctc
     8161 aaacttggct aattcaatcc cagtaggaat gacccgtttt tcaaccttga ccttataatc
     8221 agatagcaag tcacggacaa tctcactagg acaaataacc ccatccacat catgcaggaa
     8281 acctctaacc agatacttga ccatactcgg ccggatcaac atccccttag caatataatg
     8341 gacatagtct tcatactggg tgtgataggt atggatgact ggaattttca attcacgcgc
     8401 aatccaaatc cccaacaggc caagagaaaa ttctgtctga gtatggataa tatctagctg
     8461 atactgttta gcaatttcaa gtgccttgct aaaacctcgg taggcaaagc gacgatcctt
     8521 aaaagcaaag aaaggaacac ttggaatgcg gataatttgc caatcttcgt agcgattgac
     8581 atccttatct gtcgtcgtaa agataaaaac agcatgtccc tgcttttcaa gttctgtttt
     8641 caaggttcga atactggtcg caacaccaga aacttgagga aaataggtat ctgtaaataa
     8701 accaattcgc atagattacc tcacttttta ctttctccct aaagcggctt gtttctcata
     8761 aaagtccaac cagatttgta acagatgctc ttcagaatac tctctggaaa tattcttagc
     8821 cttttctttg agatctttta aggcagcagg atttgcttga tattccaaaa tagcctcttt
     8881 catctcttct ctacccgctg tcgcccgata atttccctcc aaaatcacct tatagagatc
     8941 taaatcacgc aacataatag gagcctcaca actcgcagct tctaaaatag tcataggaaa
     9001 gagctcattg taactaggca acaagaaaag atccgctaga gcatacaatt cgcgcatccg
     9061 ctctggcgat acaatgcctg gaaaaatcaa atttttaggg ggattttcca taattttctt
     9121 atagtgttca taaccatctg tcataccacc aaaagagaag ccaccagccc agataaaggt
     9181 aatctgaggc aattcctcag ccagacggat aaagtcatca atccctttac gtttctgaac
     9241 ttgcccagca cctactacga taaactgatt gtcactaaga ccaagatctg tgcgcagtct
     9301 gactacctct tcttgtggta gaggatgcca tttttccttg ttgacaaagt taggaatata
     9361 ggtcactttt tcacgtggaa taccagctgc taccaaatcc tcaataaaca taggattgac
     9421 cacaaccaag tgctccatcc ggttgtaaaa agaaaataca tagcgtttca caattccctt
     9481 taagaaaaat ggaattttca aacttccctc aagtgtagct ggcaagaaat gcacatagcc
     9541 aatctttctc cctgagcgtt tcttttggaa ggttgataaa taatagggaa aatcaatcgt
     9601 atgaaagtga gtcacatctg cctcgattgg aagattttct gtaacaatca attggtcctt
     9661 ggcagcacgg tgaagaagac gaactaattc acggtaagca cctgaaactc cctgtcctgc
     9721 tactttctca cttgaactca acatattgat gcgtaatttc tttttctcca taactactat
     9781 tatatcattt tctttgaata aaatcagcaa aagaaaggag agactagagg aaaagagggg
     9841 aaatttcctc gcttttccaa cagtctctca catgctttta tatgtttact taatgcctag
     9901 ggcaatgcgg gcatagcgac tcattttttc aactgtccag gctggatacc agactaattt
     9961 aacctcagta tccgttactt ctggaacctc tatcatagca tcataaatct ggtctgtcaa
    10021 aaggtctgct aagggacaac ccatagttgt caaagtcatg tcaatctctg tttgccctgt
    10081 gtcaccgtca aaacgaatct catagatcaa accaagattg acaatatcga ttcccaactc
    10141 agggtcgatg acttcttcca aggctgttaa aatccgtgtt ttgatgtttt caatttgctc
    10201 ttctgtataa gccatatttt cctcactctt agtcttcaat aaaatcacga agcggtttgc
    10261 tacgacttgg ttggcgtagt tttctcaaag cctttgcttc aatctgacgg atacgctcac
    10321 gagttacgtt aaagactttc cccacatctt caagtgtgcg catttttcca tcatctagtc
    10381 caaaacgtag acgcagaaca ttttcttcac ggtctgtaag agtatctaag atttcatcca
    10441 attgctcacg caagacgata cgagtcgtat aatccactgg attttcaatc acttcatctt
    10501 cgataaagtc tccaaggtgg ctatcgtcct cttcaccgat aggagtttca agagatactg
    10561 gttcttgggc aatcttcaag atttcacgaa ccttatcagg tgtcatatcc attcgttcag
    10621 caatctgttc tggtgtcgga tcttgcccca attcttgaag gagattccgc tgttcacgaa
    10681 ccaatttatt gatagtttca accatgtgaa ctgggatacg gatggtacga gcttggtccg
    10741 caatagcacg agtgatagcc tgacgaatcc accaagttgc ataagttgaa aacttgaacc
    10801 ctttagaata gtcaaacttg tcaaccgcct tcatcaagcc catatttcct tcttgaatca
    10861 agtcaaggaa ctgcatgcca cgaccgacat agcgtttggc aatggaaaca accaaacgaa
    10921 gattggcttc cgcaagacgt tgtttggctt cgatatcacc agcttcaaca gccagtgcca
    10981 actctttctc ctcttcattg gtcaagagag gaacgacccc tatttctttc aagtacatac
    11041 ggacagggtc attgacctta gcagaagttg acccaatcaa gtcctcatcg ctgagttctg
    11101 gttcttcttc attgctaaga acacgcgcac ttggatttcc ttcgttatct gtgatagaaa
    11161 tgcctgcatc ctgaatccgt tgcaagagat cttcaatccc atcagcgtcc aaggtaaaag
    11221 gaataaccag acttgcattg atttcatcat ctgttgctgt ccctttttgc ttatgattac
    11281 ggataaattc tgctacctgt acgtcaaatg ttgttacttc tttttgtttt gttgccatta
    11341 ttactccatt cttctctttt gggaaattaa acgttccaat tcttctaggg ctgtatctgt
    11401 atctcctaca tggctagctt cctgcacctt ctttttgatt ctcatattgt cctgattcaa
    11461 gagagccttg tttcgagtca tctctacttc actaagttcc tgcggcgata tctcagcagg
    11521 caaatcctga gctaaaactt ggtaccaagc tctttcaact tcctctgtct gctctgctaa
    11581 aacttctgga ggaagatttc catactggcc aagcaagtca tataagacct gaaattcagg
    11641 tgtagcaaat gcaaagtctt ctcgcaaacg gtaatcgttc aaaacaagag gggattccat
    11701 catccgatag agtagatggg cttctgccct cataatagcc gataactgct tggtgacagg
    11761 catggtgatt ggcgtcggtc tggaaattct ttccatgcga ttctgccttt gcacctgacg
    11821 actctcatta acaatctgct caatctgggt ataatcaaag gacgccagac tgtcagctaa
    11881 aatatgaata tagctgtttt gagcagcgat ggacttttct tgaacaatca agggagctat
    11941 tttttcaata aactcaatct gagcctgcag attttcactg ttttcaggtt tgtactgatg
    12001 aatgtagaac tcaatcggac taatacgagt ttttgttaat agataggcca agtcttctgg
    12061 accatttttt tgtagatact catcaggatc caagttatca ggcatactaa cgatttgcac
    12121 aggcatatca ccaatttcat ccaatgcttt caatatcgcg gcttgcccag ccttatctcc
    12181 atcgtaaaca agaaccaatt tcttggttaa ccttttcaga tgctcaacat gctctcgact
    12241 caaggccgtt cccatcgacg ccacagcatt ttcgattcca gcccgatagg ctgcaataac
    12301 atccatgaat ccttccatca ggtaaatctc actagttttt ccagaagatt tttttgccct
    12361 atccatatga tataattcgt aacttttgtt aaaaattgca gtcgatcggc tgtttttata
    12421 cttagaagtt tgtgaatccg ttttttgcca gatacgacct gagaaggcaa tgacctttcc
    12481 ttggtcattt gtcaggggaa acataatgcg attgtgaaag gtgtctacaa attgattgtc
    12541 atccgagaga taaaacaggc ctgaatccag taaatcctct tcacgatact gatcagacaa
    12601 acgttgatag agatagtttc gttctgaagg tgctaaacca atccaaaaat gtttaagcac
    12661 ttcatctgtc aaaccccgct gataaaggta atttctggcc tcttcgccca tagtcgttgt
    12721 catgagaata gcatggtaaa atttagccgc atcttcgtgc atatcataaa gatcttggta
    12781 aggcgaggct ggcttctgtt cactataaag cggtttttca acctcaatcc cgacacgctg
    12841 acctaagatt tggacagcct ccataaaggg aaccccttgg tactcctcga tgaatttaaa
    12901 gacatcacct gagcgaccac aaccaaaaca gtggtaaaac tgcttgtcct ctacaacgtt
    12961 gaaagaaggt gttttttcac catgaaaagg acagagccct agatagttcc gtcctgcctt
    13021 ttgtaaagaa atcacatctc ctatgacttc cacaatgttg gcattgtttt tgatttcttc
    13081 aatgacttgt ttgtcaacca tacacaatac ctccatgtta tcatagttta ctttatatag
    13141 tatactttat ttcagaaaaa aagtaaacca tttcactcat tttccctact ttattcaaag
    13201 agttgataat aatcagagat tttcattttt gctttttctt cttggtttaa atcttggata
    13261 atccgtcctt ctttcatgac aatcaagcga ttgccgtatt tgagagcatc ttccatatga
    13321 tgagtaatca taagggctgt tagctgatct ttcttaacaa attcatctgt caattccatc
    13381 aaagcaacac tagtctttgg atccagggca gcagtatgct catctaacag gagtaattca
    13441 ggtcgcttca aggttgccat caagagactc aaagcctgtc tttgtccacc tgataagaac
    13501 tcaatcggtg tattcaagtg tttctcaaga ccatttccta ctttttcaat ggttacctga
    13561 aattcatcct tatagctagt caagcgtcgt ggtaacaatc cacgcttttc accacgaaac
    13621 ttggcgatta aaagattttc agcgaccgtc atacggggag ctgtccccat ctttggatct
    13681 tggaagacac gagacaggta cttggcacgc ttctcgggtg aaaacttagt gagatcttca
    13741 cctaaaatac ggatagttcc actagttagt gataaggtcc ctgctatagt gttaaagagg
    13801 gttgattttc cagcaccatt tccgcccaaa atcgtgataa agtcccgttc aaaaatttct
    13861 aaggaaacat catttaaaat aatcttttct tcatcaaagc catttttaac gattttggtt
    13921 gcatttttta attctacaat tgctgtcatt tgcttaactt ggctcctttc aagattgttt
    13981 gcttaaatgt tggaatcatg aggcagactg ctaaaatcaa ggcactgtat aaacgaaggt
    14041 aacttgtatt aaagccaagt gcgataactg cccacactaa aaattgataa gcgatagaac
    14101 ctacaacgat agtaaccaaa cgctctgcca agctcaaact cttgaaaata acttctccaa
    14161 taatcaaact tgcaagcccc acaacgataa ccccgatccc tcgagacaca tcggcataac
    14221 cttcttgctg agcaatgagg gcacctgcaa gggcaatcac accatttgat aagaccaagc
    14281 ccatgagctc catgcgtcca gtatgaatcc cgaaacttct agccatatca ggattatccc
    14341 ctgtagcaat ataggcttgt ccgagtttag tgtccaagaa aaagagcatg agagcaataa
    14401 caatactcac aaagatgaga cctgtcaaga gttgattcaa atccgaatca aaaggcaaaa
    14461 catcctgaat ttgcttggtt ccaagcaggc ctaaattcgc acgtcccata atcaagagca
    14521 tgattgagtg acaagaagtc atcaccaaaa tccctgagag caaggttggg atcttccctt
    14581 ttgtataaag aaggcctgct gccattccag ccaaacaacc tgcccctaca gcaacaagtg
    14641 tcgctaaaaa tgggttcacg cctttggtta tcaaagtgac agcaacagct cccccaagag
    14701 ggaaggaacc ttctgtcgtc atatctggaa agtttaaaat cctaaatgtc ataaagattc
    14761 ccagacctag aatagcccag acaaatcctt gagaaataat ggaaacaatc atattttatt
    14821 taatcctttc tatattcatc tttttaaaaa atgggaagag tctcctcctc cctaccttat
    14881 ttattcgatg acttgtcctg cttctttgag aacagactca ggaatagtaa tacctagttc
    14941 ttgtgctatt tttttattga tgactgactt accagttgaa aagacattga ctggggtatc
    15001 ggctggtttt gcacctttca agacttgcac aatcatttta cctgttgcca caccaaggtc
    15061 atgttggtca attacaactg atgccaaacc acctacttct accatagctg tcgcactggg
    15121 ataaattggt ttcttagaac tttgattgct agagacaacc gttggaaatc ctgatgcaat
    15181 ggtgttatca attggaaccc aaatagcatc taccttgcta gtcataacag tgacagttga
    15241 ggcaatttca tttgttgaag gaactgcaaa tgtttccact gtcagacctg ctttttcagc
    15301 ataagcctta aattcttcga cctgtgtttt tgaattgtct tcgctacttg agtaaagagc
    15361 tccgattgtt ttcacattcg gtgtcagagc cttgatgagt tcaacttgtt gttgagctgg
    15421 attgtggtca gatacccctg taatgttgcc acctggtttt ttcaaatctt taaccaagtt
    15481 agcaccaatt gggtctgtaa tagcggccat gataaccggt aggtcttttg ttgcactagc
    15541 caacccttgg gctgctggtg ttgcgatacc aaccacaagg tcattcccat ttgcaaccaa
    15601 ttgtttactc attgtcgcaa ccttactttg gtcaccttct gagttcataa aatcaatttt
    15661 aacttgatca tctttatatc cttcttctgc aagtccatct tggatccctt tataaatcaa
    15721 atcaagggat ggatggctca caaattgaag cacaccaatc ttagttattt tcttctcatc
    15781 cttattattc tgagcttctg atttattcat tgaagaataa atcaagcttc ctgctactaa
    15841 gactgctaat gcagcaataa ttccaattaa acgtttattt ttcattctgt ttctcctttt
    15901 tatttccttt aacatatttc acttatctaa acaagcgacg ccatcgtttt ctttccatac
    15961 taacctccat caaaaaaatc ctcacacaaa aaacttgtgt gaggacgtcg atgcgcggta
    16021 ccacctcaat tatagggaat ttccctatcg ctcagtctcg caataacgag atgcactgta
    16081 aggtgtgctt accgaatttt tataatttca aattctaaat agcattcagc ccaattttca
    16141 tcatcgccac ttatctgttt tcagctacca cagactctct aaaaagtttg tatgattact
    16201 tttctgaatg gttaaattat atcattttta aactacttgt caatagtcta ttagaatttt
    16261 tttgatattc acttttagca ttcactcttg aaaattatca acctgaatta cgcaatcctg
    16321 tcgcaattcc gttgatggtg atatgaatca atcgttcttg atcactagac aattctccac
    16381 gacgttggcg tttaatcaac tccaactgaa tatagttgag aatattaaag taaggcatac
    16441 ggtaatccag actagctttt agatatggat tgtcagctaa gagttcgtca tgtccttcaa
    16501 tagccaagat aacgttctta gtaacttgcc attcatttaa aatagtctca tagatggcct
    16561 taacttgctc gtcttcacaa agtttagcat attcaaaagc aatattcata tttgattttg
    16621 acaaaaccat atcaacattt gaaagaagcg attggaagaa aggccaattt tggtacatat
    16681 ctcgtaagat agcaatattc tctggatttt tattgataaa ttccttgaag cttgaaccaa
    16741 ccccgtacca tccagggaac ataacacgac tctgtgacca tgagaatacc caagggatgg
    16801 cacgcaatcc accgatttca gtaatagtct tacgagcggc tggacgagaa ccaatattaa
    16861 aacttgaaat agccttgatt ggacttgact cgaagaaata atcatagaaa tgctcattac
    16921 caaagaccaa atcacggtag acgtcgtaac tacggtccac tacttgatcc ataatggctt
    16981 cataacgatt tggggtattg gtatcgctct tcttctgagt aatcatacgg ttaatagctg
    17041 ccgatactag catttcaagg ttatagtaag cggcgtcttt gttaccgtat ttattcccaa
    17101 ttacttcacc ctgctccgtc aagcggatac gatccttgat agacttgagc ggttgagatg
    17161 taatggcttc ataggttggc ccaccaccac gaccgacagt accaccacga ccatggaaga
    17221 aggtaacctt aacgccaaat tcatctccaa tagcagtcaa ttgttgttga gccttgtaga
    17281 gggtccaaca tgatgacaag taaccgccat ctttattact gtcagagtag ccaagcatga
    17341 tttcttggta gttatttcgt gagtcaatcc attttttggc aaggctaaga gaaagatatt
    17401 ttctcattgt ttcctctgaa tgatccaagt cttcaattgt ttcaaaaagg ggaacaatct
    17461 gaacacgcgc cctttccgta tccaccagtc ctacttcttt taacagaata gctaattcta
    17521 gcatatcaga aaggctggtt gcatgtgaaa tgatggtctg acggatgaca tcatctccca
    17581 acttatcttt caaaacacga gccgtcttaa aaatagctag ttcttttgct aataattctg
    17641 atttttctgc gtgagtcgca gaaagaattc ggggatcttc ttctaattct ttcaagagaa
    17701 ggtcacactt ttcttcttcg ctcaactcgc tataacgaga atgaattcct gctgatttca
    17761 agagttctgc cacacaggct tcatagacgc tagagtcttg tcgcatatca attgatgcta
    17821 ggtaaaaacc aaatatctct actgcctgca ataattccac aaaatcacct gaaatcaagg
    17881 actcgccctt attttctagt agagaatctc gaatggcaat caaatccttg tagaaatcat
    17941 tggcggtttc ataacgagtc ccaacttctt catcctcaat cagataggtt ttagttgcct
    18001 gaatttttga ttgaatatca aacaaggcac gacggtaaag ctctttttcg cggtaaatcg
    18061 agttatcctt ggattgacga gccatttctc tgacttgctt gctgacgttg acaatgctag
    18121 ttgaaagaga aaattcacga taaagttggt aaatcttttt atcataatag ttcatgatga
    18181 cttcacattg agtgagtgca gactgcttca aggtctctgc tgtaacaaat ggatttccat
    18241 cacggtcacc acctatccac atacccatgg tgattggttt agcctgtttt aaattcagac
    18301 catgcgcttg cgctaagcgc ttatactccg tcgtcaaatg aggtacagct ttcaaaaagg
    18361 agctgttata atattccata gcattcgtga tttcgttagt cacttttaat tttttctcac
    18421 gaatcatgtc tgtctgcatg ataatttcga tgtaacgacg caaatcattg taccatttat
    18481 ctttattgat caaccccaac ttaacatcac ggtatttacg caaaagacta tgaatatgat
    18541 ttgttaaatc caacatactt ttgcgttgca cttgtgttgg atgggctgtc aaaacaggga
    18601 caacattcaa gtgttctagg atctcaacgg cattttcctt ttctgctacc aatttaatcg
    18661 ttgtagataa tttacctaaa tagtcctgat caatattatt ttgatgattg atttcataag
    18721 ctaaatccac atcctctgaa atattaatca aaagaggtaa gatagagaaa tagcgtgaaa
    18781 tatagaccat ttcatcattt gataagctag tcactagacg gtttagacct tgataatctt
    18841 cctgcgttga taattctttc aactgtatta ttttttcaaa ggtctctggg gcaagcatat
    18901 ttttagtaat atcttccagt aattctgtta gaatcaagac ttcttcttgc acaacacttt
    18961 tattactata attttctaat ttttgaagag acataaacta tcctttcttt atcctacttc
    19021 aacagaaggt tcattggttg attttccaat tctcggtaca acttagcgcg tttttcactg
    19081 gcatcaatat ttaagacaaa ggctactgcc actgataaga ctagaagact atttccaccc
    19141 tgggataaga aagggaaagt cactcctgta gatggaatca agcccgaaat ccctccgata
    19201 ttgacaaata cctgaaccaa catcatccct ccgacaccga gtgcaaccat ggcattgaaa
    19261 ggattctccg ctcggatacc gaccaagata atccgcaaaa tcatgaaaaa caagagagct
    19321 aaaataagac tggcaccaac aaagccaaat tcttcaatca cgatagaaaa gacaaagtct
    19381 gtatgagctt ctggcaaata acctcgtttt tcaatcgagt ttccaagacc tagaccaaac
    19441 caaccaccat tgaccatggc aaaataagaa ttagctaact ggtgacctgc atcagcacga
    19501 tcggcaaaag gattaaaaaa ggcactaaag cgcttggcta catagccaaa tactggaatt
    19561 tttgaaaagg tctcaacacc gattaggctg atagtggtca agacaaagac agaagtggca
    19621 gatacgagcg ccagaatggt tgaaaaccag cgataagcga ttccactaac tgtatacata
    19681 atcaaggaaa ccaagactaa aatagtcgca tttcctaaat cagggaaaat tcccaaactt
    19741 ccaatcagaa ctaggagaac gaatcgccaa tcattaaaag cacggggaag ccattgattt
    19801 tgagtcaaaa cttgaaaatc ataagtagct atttcttctt gctgtttgga gaatcggtga
    19861 gctaaatacc aaataataat gatttttaag tactcagctg gctgaatagt tactcctgca
    19921 accgaaatcc aaccgtatgc cccgtttacg gaaataccaa taaaacgagc caagaacaat
    19981 aaaagcattt ctattaatat aactaaaatg attagtcgct catttctcaa aaaatctagt
    20041 ctcaatttat aaattaaggc aatcagtatc aaactaacaa tccaaaagat tccttggttt
    20101 cgaaccaact gcaaggcgct cttgccttct tcaattaaaa tagcactggt ggtcgaatag
    20161 accacaatca agcccaaaat agataaaagc aagtagggaa tcaagatgga ataatttaat
    20221 aagtgcctct tactaatctt catagtatca ccactctact aggatacaga caaatctgtt
    20281 ccaaattccg ttttattttc tagttttgat tgctattata ccattttttc agaaagaaaa
    20341 aaactcttac cttacaatcc ttcgaatttt actgtttttc ataattaggg cagaatttga
    20401 aatcgtaaaa ccattttgaa caagagttac ttcaacccat tggctccgac taattatgtt
    20461 gctttcgtga atgccaaaat cagccgcaat ttgttcataa gtgggctatt ctcgcatgta
    20521 ttgaatagtt accatgagga gatcgtctag gcttaatttg gtttttcgtc caccttttgc
    20581 gcgtttacgt tgcgttgata agctgttttt aacacagcta acatctcgtg cgctgaacac
    20641 ctacaaggct cttgaaacgg ctatcgctta attgtttact tgcttcatca tccatagttt
    20701 tattgtattg tatttttgtt tcgcaggaag tctattattc ctttcgttcc aaggttttta
    20761 cgcttttagc aacaagctta cacactgagc gtttcggact taccatatca tttcgttgga
    20821 gattttatca tcaattttta gattaaaaaa gatttcccaa tcttcacaaa cttctgtagc
    20881 aggaattgta tgaatctttc taagtatctt tcctgcttct acaccatatg tgtattgttg
    20941 gttttctgaa taagttaaaa tgctatctat tgcatctctt ccgtctatcc atccattcgt
    21001 gtaaagaatg tacttcgtca tcgcagagtt caatgctaat tggtttacac atcggaactc
    21061 caagagaagc tactttctcc atcatatcaa attcaaattt ttttataatc taacttcgac
    21121 ttatcagaaa cacgcaagaa atatttttac tgattttgat ctgtcacaca atatttttta
    21181 tcatctgacc agcctttatt tatggctatc ttactactaa aatccatcaa gcacactccg
    21241 attcacttta caacactttt tgcagttttc actagtaacc tatccagttc gtctacactt
    21301 ttatttccta gatccatttt tacattatga aagttagtca attttctcta tgatgtttcc
    21361 aagtttatcc aatacaagac aagaatgatc atttagtgga attatgggaa cattaacgag
    21421 ttcttcagct ctatccttat ttgctttatc attccaggaa tcataatgga cactaattaa
    21481 aaactgacta aagagtccta atccattttt tatctttatc tgatgatctg aattatcatt
    21541 aggtgagaca tagacttttt ctcctaatag tagggctcct gcagaaaatc ctataatttt
    21601 tgcctcttta ttaagcatat gatcgatata acttttgaac tcctgattaa cataagtagc
    21661 aatatatttt tccgtatttc caccaccgat gataattatg tcagcatcta gatagctatc
    21721 aagatcaatc tgctcagtgt ccaggagaaa gtaatcaatg tttagattag gaaattgact
    21781 ttgaaaaact tccgtgtact ttttcatgta cggttcccaa ttttctcgaa aaactgtaaa
    21841 aatgataatt cttttaatct tggttgataa tacaatttta tcaacaatac tatatttctt
    21901 cattggggga ttcccaccca tcaaaaaaat ttgttctttc aagttaacac actttctaaa
    21961 gatacataaa gtttaaacaa gtttattcac gtttctaaat tataattttt tcttaaaatg
    22021 aataattcta tttgcctcct gaaatccaat attgagatga aatcttatag aatccgtatt
    22081 cgttaaagta cagtcacttg caaattcctt acatccttta tttttcgccc attcctcaca
    22141 ttttgtacag agatttttag caatatcctt taaacgatat tcctcgtcaa caataatccc
    22201 ttctaagaat ccaacaggac tatatttaca accttcaaca taatcaaatc tgagtgaaca
    22261 tagtgctaga cctacaattg tgtcaccttc aacttcagta aagattgcag tatttttgcc
    22321 attcgtatat ttttttactt catcaatagc ttctttatcg gtcaattggg gccataattg
    22381 tttcattagt ttagccgttt ttataaaatc ttttgttatt ccatccatat tgatgttcct
    22441 ccgcaaatta caagtaaatg tttcgaatca tgctgatact ttgttactca ttgattgata
    22501 ccaataccat ccccttctac ttttcgactg tctcagatcg gaagagcaga gccacgcact
    22561 cagcggttcg gacttacctt atcatttcgt cggtttccct cctcattcta cgagtcctat
    22621 cgtatgggag atcatttact tctacttcgc tgatgcctca gcttgtacaa gcagtgatac
    22681 tgcctcaaca tggtgcgtcg tagtccagtt tggcgatgat ttccttgtgt gtatccttat
    22741 tgatgatgtc taaaatctgg atattagggt ctttaatgtc tagtaatttt gtgataaaat
    22801 gtaattgttc catatgattc tttctaatga gttgttttgt cgcttttcat tatagatctt
    22861 atgggacttt ttttctaccc aaaataggct ccataatatc cataggggat ttacccacta
    22921 caaatattat agagcctgaa aaattctata tttccatctg gtattggact aaagttgttt
    22981 cctctaggat aatactcgtt atattgaata tcataatgcc cagttgtaga ccctcgtgga
    23041 gcagcaccaa ttccagtatc tccactatca agaaaaatct ctacttcaat tgttgcgaac
    23101 ccttttgaat caaagatata tctgcaaata ccattaatta ttttcatagg cttccacttt
    23161 cttttttatc attgaaaatt acttttttat aaatgtcgtc gattttattt tctattgaga
    23221 tctaatttcc ctactcagct caataatacg ttcacatagg tttgggaaat ctataccagc
    23281 tgctttcgct tcctgtggta ataaacttgt tttagtcata cctggtaaac tatttgattc
    23341 aataaaatat acatccccct tctcatctac aataaaatca gtacgtgaat aaacattaaa
    23401 tccaagagcc ttatgtattt tatatgcgga tttttgtaag gtatgagtta acttttcaga
    23461 tatttttgcg ggaacgactt cttcagctgc accaacagtg tacttgttat tataatcata
    23521 aaaaccattt tttactttta tttcaataac cggtaaaaca gtttcaccta aaatacctac
    23581 cgaaaattct ctccccttaa tatacttttc tacaaagaat gaaccaagtt caggatgctc
    23641 tttataataa atgtcaaatt gttttttatt ttgaagtatc ttaatacctt tacttgaacc
    23701 acttctaatt ggctttataa caataggaaa atcatttgcc tgaattctat caaccatcaa
    23761 gttcgaagca cattttattc caacagaact agccactatt tttgataatt ttttatccat
    23821 gctaatagct gtactaagaa acgaatttcc tgtatagtct attttttcta catcaaaaat
    23881 agcctgtagt ttcccattct cacctattcc gccatgagtt gctaagaaaa ctatatcaac
    23941 ctttctacaa acatcaataa tacccgaacc aatctcaact ttttgtttat ttaatccgcg
    24001 ctcacttttt tcaatttctc ctatctcgta cgaacagtct tgagataaat ctatagaaat
    24061 cacatcgtac cccaatgtta atagactttt actaatctac tttgcagaat tttctgacac
    24121 ctctctcttc gctaaggcca ccatatagta caacaatttt tttaataata gccattcact
    24181 taacctcctt attagaatct tattgaataa aatgaagcaa tagttatctc aaaatataaa
    24241 taataaatat tatagtattt agaaaataat ttctaatatc tgcaaaagaa agcgcttcta
    24301 tttttatttt acaatttttt aatcctattg tcaaaaatta tttgtgctta aaccatatga
    24361 gtgtgctcca tgtattgcag ttccttaaat caagcataat ccagcatttc tagctttatc
    24421 cctcctctaa aatttgtcca ttacgaaaac atcttttcca tatttaacgt gcttccaaaa
    24481 atttctaatc ttattgctct tttctcaaac tcataaagat aatagtctaa gttttcttgc
    24541 aatactctta tttcttcgtt cacattttct aatgaagttg attctgttaa gttcagtttt
    24601 gaaaagtcat acctggctaa ttttctaccg atctcatctt cactcttcag attgataagc
    24661 acttccgcca ttttgtttaa ggtggcgatt ttttcttggg tttcttctag cttcatatca
    24721 atctatgcaa tttctaacac aagctcatct ttgatttctt ggtattgttt gttcgtgtta
    24781 gatagttcaa tcataagatt aatttcagaa atcttctctt gaagactttt taaagttggt
    24841 cgtctatatg ggagtttttg gctatcgttg ctcaattgtc tgattaaggt cctacccttg
    24901 atgaaacaat tattatccct gttttcttta ttatagacaa agtaagaaga cgtttctcga
    24961 atgtagactt tatatttttt atgattttat tcttccataa tatccaattg atagttggga
    25021 atgaaaataa gaccgctctg tttgacaccg aaagacacct tgatatagac gcccttatca
    25081 actagcttct ctatttggtt ctctgcaagt tccacttcaa attcacgaac agcatctctc
    25141 ttttccttaa atgtctcaaa ggcttcctcg atttcttcag cggagacttt ctccttatgc
    25201 tgctcctctc gaaaagtctg aaaatcttcc tgaagatttt ctaatgcttg aatatctcta
    25261 acttctctat cttcaaaata acgattaaaa attgaacatc gtacaatttc ttctcactta
    25321 tttttttatg actcaggctt atctttttgc catcttcttc tagggtaaac atcacatttt
    25381 tctgttttaa ctcgatggtt agattcaact ctttagcttt tacatgcaat tcttctaatg
    25441 aataaacaga ctttagtaaa aattttaaac gactttcaat ctcttgtttg gcaaaatatg
    25501 ttttaaaaaa gtcttcatca tataaatctc gtttactaag ttggcgacct cgaattggtt
    25561 ttatcatcgt tctatctgtc atcaaaaaac ggctatgctt ttgactaaaa tcaatctgaa
    25621 catgcaactg ctttgctttc tctaaaaaat catcaaacga tttagattgc tgaagcaaaa
    25681 aataaagacg ttgtttcaat tcaaatttat gactagattc cttatatttt ttataatctc
    25741 gataggaata acgtttctca ataatttttg caccagccat tttagaaata cggtctgaaa
    25801 tcatacggag gtttcgttcc aaggcatagt tccatatcaa ctttttatct gaattgcggt
    25861 caatagcgtt gattaggatg tgattatgaa catgatcttt gtctgtgtga gttgctacga
    25921 taaacttaaa acgacctcct gtcaattcca tcatggtctc ataaccaatg cggttaattt
    25981 cttcaggtgt cagattatct tcaggagaaa atgattggat gagatgatgg gcatgaatag
    26041 tttgttggtg tctttcttgt cggtcatttc tggattcgta caacttgtca ttattgctga
    26101 agttgacatt gtatatctct accatttctg catgactagg gaagtccaag taattgctca
    26161 tgccaaaatc agataccaat ttcaaattgt ccgttttatc agggttgaga atatacttaa
    26221 ttaaacgcct acgatatttt tttccgtgcg tcgcaaaatg tttagtgact accataaaac
    26281 tccttcagtc tattcacttc aacttgaaaa tctttctcta ctccagtaat taactcacta
    26341 attcccttac tcaattcttg taattggtcc tgagaaatca gatggctctg attgatagcg
    26401 cgcacaattt gattaatatt atttccaatc cgtctcaatt caaatactaa ctgttcatag
    26461 gtatccgtgt taattgtgac aaaagccata ttaggattaa gtaacacttt tctggtgtag
    26521 actgagaaat tttgacagtg cctcttgtcg attcgctcat tcaattgatg taattctgaa
    26581 tctgttagaa atactttttt gagattggta cgataacgat aaaccatagt agcctcctat
    26641 ctcatgtatt tttcacgaaa cccacgactg agtgactgta cttgattgac ttccgcaatc
    26701 aattcttgaa cgcaagtcaa taagattgag acgtgctctt gagtcacttg atgattttct
    26761 cttgcgacaa ccagaacttc atacacatct cgactaatct gttcaaactt ttgagactgc
    26821 caaagggaga accaactttc aaaaattcta tcctgataat tctttttcaa taaattttga
    26881 cgaagaaatt ctgagaaact atccactttt tgttccctca tcatttcttt tatctgtttt
    26941 tcttcttgtc tcgtgattct aaattgctta cggattaact taatttcttg tcccatctta
    27001 ccattctttc aacattatac ttgtctgaca atgtaaggct gcctcacatt gtcagtacga
    27061 ttcctaaaga cctcagtctc tccttgttcg gtctttgcga gctcagatat tgtgtccaca
    27121 atatcccaaa aatcatatcg ccagcctatc aaaaccttct agttttgata gccaacgata
    27181 agataacttg gtggctccgc ccccaaaccc ccaggtaaaa ttcttagttg gatttttaaa
    27241 agttgagaaa agtatagcag aagaaatttg gggaagttat cacaaatcaa gtagggacta
    27301 atctctaaca ctactgcatg tatcgtccta tatttatgat cagctcccat catttacatt
    27361 ttcaggtcac tgtcttttca taccaggaat tagaattgac aaatttaatt agagaggtat
    27421 tcatttaatt gttcacttct tcgctccatt tccattacag aaatttcttc aatactatgt
    27481 gttcagctga ctcccatgat tcgttgtact acgtcctaaa cgctcacgga ataagccgta
    27541 catctttcct agtttactct cgtaattcac gtatataggt tacgacacct atttggattt
    27601 tagagttcct catccgctat atatggcttc aagtcacgat tctgtttgta gagccttgat
    27661 ttcgctaatt ccttcctatc ccccctacct cacgatattc aggattagga gtcgctattg
    27721 gtttcatctg cagcaaatat ccacagagga cttggacctc agatgtacac tatgcctgtc
    27781 ggacaaagaa aaaagtaggc taaatttcta gcctactttt tctgactcta ctctgataaa
    27841 gccgtctcat atatagacat tttatgcttg aaagaatttt ttcctccctc taattgattg
    27901 atgatatgat tttttatata tttttcacta acatatccct gtgattcaat ccatccgtta
    27961 actccatctg actccataat aacaacttga tctgtcatag aatttgttac aattgtagca
    28021 ttatgtgttg ctaaaataat ttgacgttga gctttcacat ctctaaactg ctgaactaaa
    28081 tgcctgtaaa tataacgatt gtctaggttg tcttcaggct gatcaataat caatggtctg
    28141 aagtctttag aatagtcact atatgctaat aaaaaattaa gcatggctac aactttttgt
    28201 cccaaactta atacaccaac ttctttatag agaatatcaa gttgttgcga agattctttc
    28261 gagttaatat taaactccaa aaatcgtgta ttttctttag aaaaaatttt tcgtttatat
    28321 gcacctaata agtgagaacc ttttttcaaa atgtcataac tattgaaatg agcaatatag
    28381 ttaactattt tttgattatt gaaatccttc attatagtca gtaaatgttg ataacttcca
    28441 tctttctcac ttataatatt ttcacttaac cattgattaa cccatgattc ttgttcataa
    28501 tcatatatac atacaatatg caatttatct gctgcactaa tttctactcc atgtaaaata
    28561 tgaggatgta tatcataaat cggataattt ttcattatga ttgagactgc catttgtaac
    28621 tttttaatac ctttggtagt attatgatca gttactacaa ctatttctat tccatttttt
    28681 atgattgcct ctgctaacat aagaaaacta atatattctt ttgaactaga aaaaacaacc
    28741 ttatcaaaat tactaaaaaa aattgtctta tcaactttta ttttcttatt ttcaaaaaat
    28801 atatcatata gttcatcttc agtaattttt ctatatttcg ttgcagtcca attagaaaat
    28861 agcttgtaat cataagaaac aggtgtatgc aaatgaatta aagtcttgtg aaagctaccg
    28921 aatttctctt tggaatttgt tagttcttga taaacagact ttatcttgtt attaaaccct
    28981 ctcatttcta ttctcctaaa aatatcaatt gtttattttt caagtaattc attaagtctc
    29041 ttttccccca ccttcaacat ctcttcctct accttgctcc attttccgaa gaggtattct
    29101 tgtagcactt ctgctgctga agttgtattt tcttttgaat catatacaca acttctatct
    29161 cgttgataaa tttgaatgct ttcaaagata gccagttctt ccaattgtcg tgtattatca
    29221 actagatgat ttacaatgaa atcatgatgt tcttttggag ttgcgcgtgc ttgatttgga
    29281 ttgatagcgt acagttcttc gtatcggata agagtgctca gataggacag ctcagacttt
    29341 gtcgcaatca aggctaattg tacttcatat cccttacttt tcaagagttg tgctgtttcc
    29401 tttggaacgt caatcgttcg taaagttccc tcgatcaaaa gattgtatcc caaactactc
    29461 aattttgtta ctaaagactc taccattttt cctgcaaaat ctttggtgta ttcaacgcta
    29521 tctttgccat attcttgctg cagttctaaa tagtgtggat gctgagaacg aaaactatcg
    29581 ccatctatga taacaatatt tccttgaaat tctttctgtt taattcgatg aattgtagtc
    29641 ttaccagcac cactttgccc tccaagcaaa atcgctatag gttgcttact ggactttttt
    29701 cctcttgtca gtgaacgaag attccttgct agagcatgtt tgaattcact atcagtataa
    29761 tcttggattt ccattaagct accatccgct tttcagatat ctctaacata cgttcaattc
    29821 catccaaata gccactatat ctctctattt catcaaaagt ttctactaaa tagatattcg
    29881 tatgaatcaa atcagataga tcatcactca ttaaaatcca aggattagat tcatcatcaa
    29941 tgctaattcc ctgactatct tgatagcgat agagtcgaga aagtagatta gcacctcttt
    30001 ctttcacaat ttcaattttc aaagtcaatt cataatcttc aacaggattg agcattttat
    30061 cttctcctac aatatcgaca taagatacat taaacttctg acaaatgatg tcaattaatt
    30121 ccgtagagac tgaactcgtt ccattttcat aacgactcaa gctatttcga gaaattccta
    30181 taattcgtgc aaattcgggt tgtgttaagt catgtgtttt acgtaaggat tttatgttct
    30241 ttccaatcat agcaaactcc tttattttta taattcaatt atagcataaa aaagcataac
    30301 gcaccaaaaa tggtgcatta tttcttgttt ttctatccta aactttactt ctataaaagt
    30361 cacctaaaga gccataaata tttattcttg tattaatttt ttcgatgcgc aaacgatatc
    30421 tacaaataca tctataacga ttcacctttt aggattttta ttgtcaaaat tgcctttatc
    30481 tacaaagaca aaatgcttat aaaatagctt gaaatcaagg attatcacct ttttcgttgt
    30541 agcaacactc cacatgtgat tattaggcta ttagcaaagc gtatccaata cctcaataaa
    30601 gtgttgtttt tactgatatt ttaactatat tgtatagtct actatttaaa tctcaattag
    30661 gatattttat agaataccca aaattcaaca ataactaaaa gtaagattcc attgtatttc
    30721 cttgttggtt tttcatatca cgaattttat ttttcagaat attaaagtta caaatttcat
    30781 ctctaatatc gttatccgct ctgtagccat taatcatctc agtcagagtt ttccctttac
    30841 taccattctt tatagtagta tttactcttt ttatactgct ttcaaaaggc tcatatgttt
    30901 tatacttaat tacttcgtct ttaaaattaa ataaaggtgt atccggctta gcattccata
    30961 aaataatcaa ccacattata gcattataaa gctgctttgc agtttcattc cacttttcag
    31021 gttgtaaatt tccactccct gtattgtcat attcttgtct attatttaca tgagaatcac
    31081 ctacaagcgg attaaaaaga ggtagccctt tgtgattaat tagttctaaa aaatcccttg
    31141 ccgcacccat gcaacactga ataacttcct tcttgccatc aattttactc tcagcgataa
    31201 atacataata ttcatcttca atagttgctc ctgcatcact atgtttttgt tgatttgcta
    31261 acagcttaat atgtgcttta ggctaaactt caaaatctct aacaattctt tgtcttgttt
    31321 catgtcctct acaattcatt taagttctcc tttacaagtt tagtaactag ccttattata
    31381 ctatataaga tatgaaatgt accataatct tcatcaacta gtttttagaa aatcacaaat
    31441 ccatctggag agatgacaag ctgattctcc aattcttggc aattgcttgc tagtgctact
    31501 gcttctttct ctaaaagata atcttctgtt gattggttga atattgcttt gaggatccgt
    31561 ccttcgtatt tccattccag agctactaaa tcagatttga tttcttgaag gctatacttg
    31621 ccatgcgaaa taattactga cgcgtatttc cgaatcttaa tcagcctctt cataaagttc
    31681 agcatatcat tgtcacttga tacacgttcc caaggcatac aacgacgaca atctggatct
    31741 ggtcctccag tcaaggctag ctcggttccg taataaatgc acggtgttcc tttttgtaaa
    31801 aagagaaagg ctaaggctga tttaaccagt tgaacatctt cattggccgt ccacaggatt
    31861 cgctctgtat catgtgaatc caagagatta aacatgacct ctgaaatctg ctgcttgtaa
    31921 tacatagact ctccattgat ttcatcgatg aactggtctg tcttcttaat tcctcgtaag
    31981 aaatagtcct tgatactatc agataaagga taattcatga tggcatggaa ctcatctcca
    32041 tttagccaag gctgagatgt atgccagact tctcctagga tataaagatc aggattttta
    32101 gctaaaactg ccttacgaaa atccttccag aactgatggt caatctcatt agccacatcc
    32161 aaacgccaag catcgatatt aaactcttca atccaataag tcgcaacctt taaaagataa
    32221 ttcttgacct ctggattggc tgtatttagc ttaggcatat agtcctcgaa accaaaaaca
    32281 tgatagggta agtctctctt attaactagc ttttcagttg tcactgggaa ttgttgaata
    32341 tggaaccaat ccttataagc agactgttca ccatttttga cgacattttt ccattgaaga
    32401 gattgcgaac caatatgatt aaataccgca tccagcatga ctttcatgcc acgatgatgc
    32461 gcttgatcca ccagttcccg aaaggtctcc ttgtctccaa aatgacggtc aatttcaaag
    32521 taatctgtcg tattgtactt gtgattgctt gtagattcaa agatgggaca aagatatagt
    32581 ccagtaatac ccaagtcttg caagtaatcc atatgatcaa taatcccctg taaatcacca
    32641 ccaaagaaat catcgctctt aggtgtgaca gatgaatccc agtctaaagt cccttctggg
    32701 tttaatagag cattgccatt ggcaaatctt tcaggaaata tctgatacca taccgtattt
    32761 gaaacccagt caggaacctt gcaggcatca atctcatgaa gataaggcaa cttaaatcca
    32821 ttcccaattg catgaagatt ttctagagaa ttttccacac accctttatc gccatacaaa
    32881 atattttgac cttctgtatc tatgatctca aagagatact ggatatgtgc aaagtcaact
    32941 gacacttcaa cctgccaatg gtcaaataag gtaccagaag ttatcttgac catttctttt
    33001 gtatcctgat aaaactcctc cataaagata aaagggtccc catagtgcaa gttgatgctt
    33061 tcaatgtccc ctttcttagt tcgaattcga atatggagtt tcttatcctt ataaagatag
    33121 gcatactccg actcaggcct atggtaaata gcactcaatt ccatcaattt gtctcctaaa
    33181 gtattcattc aaattttacg caaacgtttt caaactcaat aaatccagta tactattttt
    33241 gtaaactatt tgcaaggaat gtccgttgtt aaaggaacta tcttttaaag tatacaaaaa
    33301 gccttaaaaa aggctttctc tatatactaa tcctctttcg gttttgaaaa tacttctact
    33361 cgctgagcta ggactttgat ttctacaggt aggttatctg atttatctcc gtcaacatct
    33421 gactccaatt cactatctga agagatttta atattacgcg ctttgatata ctcgatatta
    33481 tcatttgcga caacatcccc ttttaataaa tcaggaatga cggataattt ggagaatata
    33541 gaggcatctt tcagaatcaa aatgttggca tagccgtcct tgttttcttc aaagattttc
    33601 ttatcagcga agtaatttgt caaaagaacc aaaacatggc tagcttcacc aacataattt
    33661 ccattttctg tctcaacctt aatgttaaag acctgatctg tcatgacaga cttcatggta
    33721 tttacagcat aggttaaaat accgaatttt gttttgtcct ctatttcaac attgtgaatc
    33781 gcctcaggca gagaaccgat actaaagata taaccaaaat agttgtcatt tgctttaccg
    33841 atatcaatct tattggttaa atcaaaatcc agttcgtcaa ttgcgtcatc gatgtcttga
    33901 ttgatttcca aaaattttgt aatgaggtta cccgtaccgc ctgggataat ccctaactta
    33961 ggaatgtagt ctctctcatc aatacctgaa atgacttcat tgacagttcc atctccacca
    34021 aacacaacca ctgcatcata ccgctcacga gaagcttctt cagcaaaatg tgttgcatcc
    34081 agcgcttttt cggtaatttt ggtttcaaca tattcaaagt attcttttgc tttattctcc
    34141 agcttttctt tgtaatccaa agccttctcg ccaccagaag tagggttgat aattaccatt
    34201 gcttttttca ttgattttat ccttaatttt aaatagaaat gtttacattt cgtcgtatgc
    34261 aagtaaatgt aatcctatta tacaatgaaa atacagaaaa gagaaatctg acgtactgga
    34321 gattaatacg cttttattct attttcccat cgcctaacta catcctttaa gggttcatcc
    34381 aagtaagaat aggccttatc cttgatccaa tcaggaatac cgtaagctgc ctctgctatg
    34441 ctacaagtga ttgctgcgag agtatcactg tcgccaccaa gtgagatggc atttcttatc
    34501 gcatcttcga agtctctact ttcaagaaag gcgataatgg cttgagggac agtttcctga
    34561 catgtttcgt taaaacgata gttaggacgg atttcatcta aagtttgaga tagattgtaa
    34621 tcgtattctt tttctatata atccttaatt cgtcttttac actctgtagg attgtcgtta
    34681 attgattgct cgtactctct acaataacca ccaaagtaaa aacgacatag aaagatagca
    34741 tcagctgtag ccatagcgcc tttgacacct tctggatgat tatgagttac ctctgcagaa
    34801 agactcgtaa gtcctctaga tgatggccat ataccagttt tcgcataaaa accacagtcc
    34861 atgatccaag cacatggaga aatacgcata gctgatccat tcccaaagct attataaggc
    34921 tcacggttat cgctgtttag ccacgcatta aaccgagcac cgtaatcagc attcggatac
    34981 attctgccat atttcttcat cgcgtcaatg aagtcgtctt tttgtccacc attcataatt
    35041 gcttctgcaa cagcacaggt cataaccgtg tcatctgtaa aaaagcagtc cttccgaaat
    35101 aaaggaaagt cctttgtttt gatattgttc cattcgtaaa cagaaccgac aatatctcca
    35161 ataattgctc caagcatcag attcctcctt gttcattttg atgcttttta tattggttat
    35221 ctaccatatt tattttagaa aataacatcc tgttggattt taaaaatttc atttttttca
    35281 aaatagggtt ttaccatttc tttccaccta gctctatgaa aattgattga ttttaaagga
    35341 gataggccat aatttcccaa tgcataacca tcatttactt caacaacaag tgttctgcca
    35401 tcgcgagtaa caccgatatc tagtccataa gctattggcg catctttcca acatgatatc
    35461 gcttcatcaa ttacacttgc atcaaattgt gcatgataat cacctgtata gggtcgaaca
    35521 tctaatacgc gaccatctaa cacaaaacaa cgccattcag ctatgaattc tacaacctca
    35581 ctaatccata taggatagtc gaaaggtaga ccaataccta ttaaatcatg ggttccatta
    35641 acaactcttc cagtaaagac ttttgaacca gctttaggct taataaattt tccccaatta
    35701 tcaggtatat tcacaatctc tcctaaaata ccagcataaa tctttcgacc ataaaactct
    35761 ttaagctcaa taggatagtc ataaaccgga acgtttaagc ccatcatttt tagtaatgct
    35821 ctagtctcca ttatataatc tacatctata tcttcacttg ttaactcttt tattttagaa
    35881 aaagattgat ataaaataac ttcttctcct tgtaagtagg cacctacttg agcattgtat
    35941 ttattaattg aaacctcact tagtaattta ctttgtctaa tataaacaac catttcatca
    36001 ctcctatatc actagtgtta caccaatttg taaaaaataa tagcaatttt gctcttattt
    36061 ttttgagtaa atagccccca taatatcatc gaaataatca acggtattta ggagtaattc
    36121 aataacctgg gactttgtta gtcgcattcc ccttctatct ctagcatctt ctactaaatt
    36181 ttcaagtttc tctagatttt tatcatccaa gctaatcatt attctatttt tatcggttgc
    36241 cattttcatc acctcaagtt aattctatca caggtgtaac acttgtgtca actggctttt
    36301 ataatacatt agtttaaaag tggagaggat ttttaacaca gtaactttaa atctttggta
    36361 ttaaaaaatt ttcacaatat ttatagaaat aaaatctgtc tcaaatcagt tatcaaatct
    36421 agtataaatt atgagcggct actctaatac tttccctcta aacaagaaaa agacttacac
    36481 tcaagggttt tcttcccccc cttcgttata acgttttgac tcttttacta gcaaaggtat
    36541 atactcacaa ggaactttgg ttgactattg aatctctcca acttcttctt taacatatcc
    36601 ttctacatct tcaatctcta caaacattgg gtctacgtga cacaagaaat gccaaacttc
    36661 gatccctttt tttctgtaaa gaatcgcttc accgtcttca cttccgaaaa agcttctgtc
    36721 gatttcatat ccgttgcttt ctaagaagtc ttttgcttta cgatagttcg tttctcttgt
    36781 ttcgacatag gctttaactt catggttgtt aacgacatat gcatcaattt ttgaatatcc
    36841 ttcgatcact ctatcatttt tgagggataa atttgaaatc tctttccaaa taatgtttac
    36901 attttcctca ggatcgaaca taaatttaga taaaggaaca atatttccgt taaaaataat
    36961 ttccatataa tccggtatgt ttttaggatt aaaatactcc acttcaaaac catcttctgt
    37021 ttccagagtg tatcccggga tttgagctac aaaggctttc ccatcttcta tggaatcaaa
    37081 tgctactaaa tctttagaat aatcattttg gtacaattcc aatataacca tcgataatct
    37141 ctccattttc attatcaggc taatgtaaat aagcacgtca cctgaccaat tcaggctctc
    37201 tgtatcatct catcatattt cctacttact ttacgagtcc tatacccaga acacacctta
    37261 tcgaccttcg gtctcacctc gtcgcattgg ctgaacatct acttttactt cgctgatgct
    37321 tcaactcgta caagcagtga taccgcctca gcgtgatgcg tcagtgggac tcaaaaggtt
    37381 tggggaacct tttgaggatt aactacgttt ctctaataaa cttacacatt caacttgttc
    37441 atcattgtcc aaacctatgt tgagattttc ttctataatt ggtagcttaa aagtaatgga
    37501 ttttagccat tatccgttag attgtttttc ttcataaact tgaatttcag aaatcaaagc
    37561 tgaaattaac tacctacgct ctacatcatt catgacttta tagagcttat caaaatagat
    37621 cagaacctta tatatgttat ctcctgtaag cttttcagct tcaatagtct gtttctttgc
    37681 tttcgcatca attagtgatg attctaattc atctattttg tcatacatac gatatagtct
    37741 atcatctaaa tcctgtttcc ttctcttata atgcttatct tcaacatcta aattatctat
    37801 ttcctcaatt agcttaaact ttgtagaatg actctttctc aattcctttt ggtaattatc
    37861 tatttctttt tctatttcag aggtatccac cttcatgttg attttttctt gcatcataga
    37921 agcaaatttc ggattactta ctatcttgac aatcacctct gcaacagcat catctaacaa
    37981 ttcttctcta atttgcttac tgaatgtaca cttatgacct cttatcatct gcctatgttt
    38041 acaaccatag taataaaaat ctttatactt tgtgccatct ttctttttct tgatacactt
    38101 gttcccaaac attcccactc cacatatcgg gcattttaca attccagaaa gcaagtgtgt
    38161 gcgtgtatct tttcctttat tcacatgctc atatttcttt gcttgagatt ttagcttaac
    38221 ctgagcagct tgccaaactt catcggaaac tatagcttca tgtatccctt cagatattag
    38281 atattcatct tgttcaacct gcttatattc atttcttgta ccatgaactt tttctaaagt
    38341 tcttcttcca aatgctattt tcccattata tacaggattc tttaatatct ttcttataag
    38401 acctgcatca aacaaaggat tcttaccatt ctgtcttggg atttttctaa ttccatgatt
    38461 ctctaagtat ttagatatcc cattggctcc tatcgtagta tttacatact ggtcgaaaat
    38521 cgttcttatt gcaactgcct cttcctcatt tataaacagc ttgccgtctt caagtttata
    38581 tccatacgga gcaaagccac cattccattt tccttccctt gctttttgaa tgcgaccttc
    38641 cattgtttga atacggatgt tttctctttc tatttcagcc acagctgata aaacagaaat
    38701 cattagtttc ccagcatctt tagatgaatc aatgccatct tcaacgcaga taagattaac
    38761 tccataatcc tgcattatct gaagtgtaga aagaacatca gcggcatttc ttgcaaatct
    38821 tgataactta aacacaagaa caaaagatac tccatctttt ccagatttta tatcttccat
    38881 cattcgattg aactgtattc taccttcaat agacttgcca gacttcccgg catcttcata
    38941 ctctccaaca atttcataat cgttgtaaat agcaaaagct ttcattcgtg atttttgtgc
    39001 ctctaacgaa tacccctcta tctgtattga cgtagatact cgtgtataga ggtatacttt
    39061 tattttt
//
LOCUS       DAVHSL010000015        37851 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000015 DAVHSL010000000
VERSION     DAVHSL010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.015"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(95..2353)
                     /locus_tag="VVR39_000792"
     CDS             complement(95..2353)
                     /locus_tag="VVR39_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6030314.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDCIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
     gene            complement(2582..2812)
                     /locus_tag="VVR39_000793"
     CDS             complement(2582..2812)
                     /locus_tag="VVR39_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU6030315.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3003..3686
                     /locus_tag="VVR39_000794"
     CDS             3003..3686
                     /locus_tag="VVR39_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6030316.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3686..4420
                     /locus_tag="VVR39_000795"
     CDS             3686..4420
                     /locus_tag="VVR39_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6030317.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRSQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4574..5431
                     /locus_tag="VVR39_000796"
     CDS             4574..5431
                     /locus_tag="VVR39_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU6030318.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETTLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5573..6445
                     /locus_tag="VVR39_000797"
     CDS             5573..6445
                     /locus_tag="VVR39_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU6030319.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLPSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6727..7410
                     /gene="rpiA"
                     /locus_tag="VVR39_000798"
     CDS             6727..7410
                     /gene="rpiA"
                     /locus_tag="VVR39_000798"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU6030320.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7424..8635
                     /locus_tag="VVR39_000799"
     CDS             7424..8635
                     /locus_tag="VVR39_000799"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU6030321.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8637..9165
                     /locus_tag="VVR39_000800"
                     /pseudo
     CDS             8637..9165
                     /locus_tag="VVR39_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9181..9990
                     /locus_tag="VVR39_000801"
     CDS             9181..9990
                     /locus_tag="VVR39_000801"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6030322.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSDLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10466..11446
                     /locus_tag="VVR39_000802"
                     /pseudo
     CDS             10466..11446
                     /locus_tag="VVR39_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11471..11983
                     /locus_tag="VVR39_000803"
     CDS             11471..11983
                     /locus_tag="VVR39_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU6030323.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12641..13351
                     /gene="deoD"
                     /locus_tag="VVR39_000804"
     CDS             12641..13351
                     /gene="deoD"
                     /locus_tag="VVR39_000804"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6030324.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13374..13898)
                     /locus_tag="VVR39_000805"
     CDS             complement(13374..13898)
                     /locus_tag="VVR39_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU6030325.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKATILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13951..14187)
                     /locus_tag="VVR39_000806"
     CDS             complement(13951..14187)
                     /locus_tag="VVR39_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU6030326.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14255..15175)
                     /locus_tag="VVR39_000807"
     CDS             complement(14255..15175)
                     /locus_tag="VVR39_000807"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU6030327.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15365..15732
                     /locus_tag="VVR39_000808"
                     /pseudo
     CDS             15365..15732
                     /locus_tag="VVR39_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15948..16529
                     /locus_tag="VVR39_000809"
     CDS             15948..16529
                     /locus_tag="VVR39_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6030328.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGNLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16526..17803
                     /locus_tag="VVR39_000810"
     CDS             16526..17803
                     /locus_tag="VVR39_000810"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU6030329.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17821..18483
                     /gene="deoC"
                     /locus_tag="VVR39_000811"
     CDS             17821..18483
                     /gene="deoC"
                     /locus_tag="VVR39_000811"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU6030330.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18470..18859
                     /locus_tag="VVR39_000812"
     CDS             18470..18859
                     /locus_tag="VVR39_000812"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6030331.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            18950..20002
                     /locus_tag="VVR39_000813"
     CDS             18950..20002
                     /locus_tag="VVR39_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU6030332.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20146..21681
                     /locus_tag="VVR39_000814"
     CDS             20146..21681
                     /locus_tag="VVR39_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030333.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SIGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21674..22732
                     /locus_tag="VVR39_000815"
     CDS             21674..22732
                     /locus_tag="VVR39_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030334.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22735..23691
                     /locus_tag="VVR39_000816"
     CDS             22735..23691
                     /locus_tag="VVR39_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030335.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23776..25047
                     /locus_tag="VVR39_000817"
                     /pseudo
     CDS             23776..25047
                     /locus_tag="VVR39_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(25090..25731)
                     /gene="plsY"
                     /locus_tag="VVR39_000818"
     CDS             complement(25090..25731)
                     /gene="plsY"
                     /locus_tag="VVR39_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU6030336.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            25867..27810
                     /gene="parE"
                     /locus_tag="VVR39_000819"
     CDS             25867..27810
                     /gene="parE"
                     /locus_tag="VVR39_000819"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU6030337.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            28230..30701
                     /gene="parC"
                     /locus_tag="VVR39_000820"
     CDS             28230..30701
                     /gene="parC"
                     /locus_tag="VVR39_000820"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU6030338.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            30833..31855
                     /locus_tag="VVR39_000821"
     CDS             30833..31855
                     /locus_tag="VVR39_000821"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU6030339.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            31911..32615
                     /locus_tag="VVR39_000822"
     CDS             31911..32615
                     /locus_tag="VVR39_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6030340.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            32680..33369
                     /locus_tag="VVR39_000823"
     CDS             32680..33369
                     /locus_tag="VVR39_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU6030341.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            33366..34289
                     /locus_tag="VVR39_000824"
     CDS             33366..34289
                     /locus_tag="VVR39_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU6030342.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            34304..34948
                     /gene="pcp"
                     /locus_tag="VVR39_000825"
     CDS             34304..34948
                     /gene="pcp"
                     /locus_tag="VVR39_000825"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6030343.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            35116..35346
                     /locus_tag="VVR39_000826"
     CDS             35116..35346
                     /locus_tag="VVR39_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU6030344.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            35396..35476
                     /locus_tag="VVR39_000827"
     tRNA            35396..35476
                     /locus_tag="VVR39_000827"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35430..35432,aa:Tyr,seq:gta)
     gene            35486..35557
                     /locus_tag="VVR39_000828"
     tRNA            35486..35557
                     /locus_tag="VVR39_000828"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35518..35520,aa:Gln,seq:ttg)
     gene            35719..36921
                     /gene="rpsA"
                     /locus_tag="VVR39_000829"
     CDS             35719..36921
                     /gene="rpsA"
                     /locus_tag="VVR39_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU6030345.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(37005..37810)
                     /locus_tag="VVR39_000830"
                     /pseudo
     CDS             complement(37005..37810)
                     /locus_tag="VVR39_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        11348 a         6749 c         8549 g        11205 t
ORIGIN      
        1 ataatggaca aagggcaagc tgtcaagaaa ttacagttat tttagtaaaa aaagaagcag
       61 aaaaatttca ttttctactc cttttctata ggatttattt ttctttttca gaacttttaa
      121 cttcagtttt tttggcagat ttaatctgaa tgtttccctt gctagtcata actgctttga
      181 gatctttttc gcttggattt tcaaggtagt agtcagtgat tgtgtcctca atacagtctt
      241 gaatagtccg acgaagtggg cgtgctccca tttttggatc ataacctagg tcaaccaact
      301 tttccttgac cttatcagtt acatccaaac gaatgttgtt gctagagagg cgcttgttaa
      361 catctgctag catgagctcg acaatctgaa ggaggttatc cttgctgaga gccttaaatt
      421 cgataatgcc atcaaaacgg ttcataaact ctgggctaaa gaagttaccg agttcaccga
      481 ggacagaatt ggtacgtcct tctctagcag caccaaatcc aacgctagct tcggtctttc
      541 ctgtacctgc atttgaggtc atgataatga tagcatcctt gaagctaacg gtgcgtcctt
      601 gcccgtctgt caaacgacca tcgtccaaga cttgaagaaa catgtgcata acatctgggt
      661 gagctttttc cacttcatcg agaaggatga gagaatatgg attgtggcga actttttcag
      721 ttaattgacc agcctcatca tagccaacat aacctggagg agcgccgacc aacttagcca
      781 cactatgttt ttccatgtat tcactcatat caaagcgaat catactatca gcagaaccaa
      841 aaagttcgat agccagttgt ttggaaagtt ctgtcttacc gacaccagtt ggcccaacga
      901 agaggaagct tccgattggg cggttagggg taccaagtcc gacacgatta cggcgaatag
      961 ccttggcaat cttatcgact gcatcatctt gaccaataac atgagacttg agatcttcgg
     1021 ctagatggat gagttgagat tgttctttct ctttcaaatc accaacaggg atattggttt
     1081 tctgctcgat aatgtgctca atagttttct cgctgatgat aggagtatcc tggtctgtga
     1141 tctttttctt ttgcatttcc ttatacttgg caatctggtc gcggaagtag gccgccttct
     1201 caaaatcttc ttctcgtgta gcttgagact tgagattttc agcctcaatc aagcgctgat
     1261 caattacttt aggatccaca aaattcaagg tcaagttcat cttagaacca gcttcatcta
     1321 ggaggtcaat ggccttgtca ggcaagaagc gatcttggat gtagcgattg gaaagagttg
     1381 cagctgcttc aatcgcagca tcggtatatt gaacgtggtg gtaatcttcg tatttctttt
     1441 gaatcccttt gagaatagtg attgtttcgt ctaccgttgg ttcatcgact ttaacaggct
     1501 gcatacgacg ctcgagggca gcatcctttt caatgatacg gtattcattg agggtagtag
     1561 caccgactag ttgcagttct ccacgagcaa gggctggctt gaggatattt cctgcgtcca
     1621 tattaccatc actcgcagaa ccagcaccaa caatttcatg gatttcatcg ataaagagga
     1681 tgatgtcttc acgtttgcga atttcttcca tgagtttttg catgcgttct tcaaattgtc
     1741 ctcgaatccc cgttccttga actaagctaa ccacatccag acggatgact tgtttacctt
     1801 ggagtttatg tggcacatcg ccatcgacaa ttttctgagc tagaccttcg acaacggccg
     1861 tttttccgac accaggttca ccgataagga caggattatt cttggttcta cgattgagaa
     1921 tctcgatgac acggataatc tcatcgtcgc gcccaataac gggatcaatg tctccacgac
     1981 gggcaatttc agttacatta ataccaaatt cttccagcag gcctttttct tggctaggtg
     2041 gcggagtttg agcagatcca cgattttggg aaccataacc gccgtttcca ccgtaacctc
     2101 cacctgattg ggttggggga ataggaggag tattgctaga aggtctgaaa ttgtttagat
     2161 cattgaagaa atcaccaaag ggatcgaagt cacgattgtt cagatccgtc atacctttga
     2221 agaggctatt gttaggatct gttttgataa tcttatagca gttttgacag aggtcaattt
     2281 gtttttgttt tccattgaga ttggtgtaaa gatgaattgt tgagtcgtta attttacagt
     2341 tttgacaaag catacatcta cctcatttct ttctttagcc tgacttgttt aaaggtcaaa
     2401 aatagtcaaa ttctatactc tcattataac aggattgggg tgtaaagcaa gtaaaaagat
     2461 tgaagctttg agaagttgtt acaatgaaaa tttttgtgaa tttggactat aaaaaaatcc
     2521 tatttgtgag acaaaaagga ttttacttag acatgcaggg acaatcccag cttgttttag
     2581 attagtagag aagttcgtaa atttccattg cgattaagtc aatgctatca aacgtatacg
     2641 tttcgcgatc ttctacgtca cgaagggtaa agattgggcc gttttcttcg tcgtggctgt
     2701 acgcaacttc tgcaacaaca actccttcgc gttcaaaatt acgttttaaa tttccgccat
     2761 cgtttgccat tgcttcaagg cggttgatga ttctaaccaa atgtgattcc attttgattc
     2821 tccttcattt cttatcgtta ctattttacc ataaaggagg ccaacttgac tagaaaaaaa
     2881 ctaagatttc tcgctaattc tgctagttta aagattttta aataaattgg ataaaaaatt
     2941 taaattttaa ttcaaaacat gttataatca tacagtattc tattttagaa agcagtgtga
     3001 ctatgaattt ttctttttta cctaagtatt taccttattt taactatggg gctgttgtga
     3061 cgattcttat ttctatctgt gttatctttt tgggaactat tttgggtgtt gtcttggctt
     3121 ttgggcaacg ttcaaagttt aaaccgcttg tttggttggc caacttgtac gtttggattt
     3181 tccgtgggac accgatgatg gttcaaatta tgattgcctt tgctcttatg catatcaatg
     3241 ctccgactat tcagattgga attttaggtg ttgatttttc gcgtctgatt ccagggattt
     3301 tgattatctc tatgaatagt ggtgcttatg tttcggagac tgttcgtgcc ggaatcaatg
     3361 cggttccaaa aggtcagcta gaggcggctt attcgctagg gattcgtcct aaaaatgcga
     3421 tgcgttatgt gattttgcca caagcagtca aaaatatctt gccagcattg gggaacgaat
     3481 ttatcaccat tatcaaggac agctccctct tatcagctat tggggtcatg gagttgtgga
     3541 atggggctac aacagtttct acaacaacct atctaccttt aacaccactt ttatttgcag
     3601 cattttacta cttgattatg acctctattc tgacagtagc cttgaaagct tttgaaaaac
     3661 atatgggaca aggagataag aaataatgac agaaaccttg ataaaaattg aaaatttaca
     3721 taaatctttt ggaaagaatg aagtattgaa gggcatcaac ctcgagatta aaagaggaga
     3781 agttgtcgtt atcatcggtc cttcagggag tgggaaatct accttgcttc gctctatgaa
     3841 tttgttggag gaagcaacca aggggaagct tatctttgag ggagtcgata ttacggacaa
     3901 gaagaatgac ctgtttgcca tgcgtgagaa gatgggcatg gttttccaac aatttaacct
     3961 ctttcctaat atgactgtga tggaaaatat taccttgtca cctatcaaga ctaaaggtga
     4021 aagcagggaa gttgctgaga agagatccca agagcttttg gaaaaagtgg gtttgccaga
     4081 taaggcagac gcttatccac agagtctgtc gggtgggcaa caacaacgga ttgccatcgc
     4141 gcgtgggttg gctatggaac cagatgtttt gctctttgac gaaccaactt cagccttgga
     4201 tcctgaaatg gtaggtgagg tattggctgt tatgcaagac cttgccaagt cagggatgac
     4261 tatggttatc gtaacacatg agatgggatt tgcccgtgag gtggcagatc gtgttatctt
     4321 tatggcagac ggtgtggttg ttgaagatgg gacacctgag cagatttttg aacaaaccca
     4381 agaacaacgg actaaagatt tcttgagtaa ggttttataa tctattttaa aatttcaaga
     4441 caagattagt gaaaagttca accagagctt tttcttatag tttgaaacta taggataacc
     4501 taggaaagaa gtgttagagg gcactagcag tttttggtat aatggaagat atttgaaaga
     4561 aaagagaagt gatatgacac agattattga tgggaaagct ttagcggcca aattgcaggg
     4621 gcagttggct gaaaagactg caaaattaaa ggaagaaaca actctagtgc ctggtttggt
     4681 agtgattttg gttggggata atccagccag ccaagtctac gttcgcaaca aggagaggtc
     4741 agctcttgcg gctggttccc gtagcgaagt agtgcgagtt ccagagacca ttactcaaga
     4801 ggaattgtta gacctgattg ctaaatataa tcaggatcca gcttggcatg ggattttggt
     4861 ccagttgcca ttaccaaaac atatcgatga agaggcggtt ttattagcca ttgacccaga
     4921 aaaggatgtg gatggtttcc atcccctaaa catgggacgt ctttggtctg gacatccagt
     4981 catgattccc tcgacacctg caggaattat ggaaatgttt catgaatatg ggattgactt
     5041 ggaaggtaaa aatgcggtcg taatcggtcg ttcaaatatc gttggaaaac ctatggctca
     5101 gcttcttttg gctaaaaatg cgacagtaac cttggcccac tcacgaactc ataatcttgc
     5161 caaggtggct gctaaagcag atattcttgt agtcgcaatc ggccgcgcca agtttgtgac
     5221 tgctgacttt gtcaaaccag gtgcggttgt cattgacgtt gggatgaatc gagatgaaaa
     5281 tgggaagctc tgtggagatg ttgattatga ggcagttgca ccacttgcta gccatatcac
     5341 gccagtccct ggaggtgtcg gtcctatgac cattaccatg ctgatggagc aaacttatca
     5401 agcagcactt cggacattgg atagaaaata agagaaacat tcgattaata gagtgtattt
     5461 tctatagcta tatctaaaat ggcagaaatg aatattaaat tttagatata agattacaaa
     5521 aggaggtctg cgtctccttt ttattgtata ataaaagtga gaggaaaaaa gaatgaaagt
     5581 gattaatcaa accttattag aaaaagttat tattgaacgt tctcgttcaa gtcataaagg
     5641 agattatggt cgtctgctgc tgcttggtgg tacttatcct tatggaggtg ccatcatcat
     5701 ggctgcttta gcagctgtaa aaagcggtgc aggattggtg accgttggaa cggacaggga
     5761 aaatatcccg gctctgcaca gccatttacc tgagcctatg gccttttctc ttcaagacca
     5821 gcaattgtta aaagagcaat tggagaaggc agaagttgtc ttgctggggc ctggtttacg
     5881 agacgatgct tctggagaaa atctagtaaa acaggtcttt gttaatttaa gccaaaatca
     5941 gattttgatt gtagatggag gtgccttgac cattcttgct aggacaagtt tgtcatttcc
     6001 ctcaagccag cttatcctaa ctcctcacca aaaagaatgg gaaaaattat ctggaattac
     6061 gattgaaaag caaaaggaag atgcaacggc tagtgttctg ccttctttcc ctcaaggaac
     6121 aattttggtg gagaaaggcc cagctactcg tatttgggaa gttggccaat ctgattatta
     6181 ccagttacag gttggtggtc cttatcaggc gactggggga atgggagata ctctggctgg
     6241 gatgatcgca ggatttgtag gccaattccg acaggccagt ctctacgagc gtgtggcagt
     6301 agcgacccat cttcattcag ccatagccca agaactatct caagaaaatt atgtggtctt
     6361 accgacggaa atcagcaggt atcttcccaa aataatgaaa attatttgtc aacaagagag
     6421 ggtaagcaaa gataaacttg tttaaaatag acagataaat ctatttcctt ctcttaattt
     6481 atgattcttg aaatgcgcct gctttaaggc taaactagac gtatcaaagt taagattttg
     6541 tttttgtaac tggaaagaga tgaacaaatc aaatacataa aagataaact catttttatt
     6601 cgtttggtga aaagaaaata catattttta aagaaagatt gatgaaaaat gtagatttga
     6661 tgtttttact tgaataaaaa gcggtttcat agtaaaataa gaactgagaa tgatggaggt
     6721 aaatcggtgg aaaatctgaa gaaaatggca ggtatcaagg ctgctgagtt cgtgagcgat
     6781 ggaatggtcg ttggacttgg aacaggctcg actgcctatt attttgtcga agaaatcggt
     6841 cgtcgtatca aggaagaagg attgcagatt acagctgtaa caacttctag tgtgaccact
     6901 aaacaggcag aaggccttaa tatcccgctc aagtctattg accaagtaga ctttgtcgat
     6961 gtgacggttg atggcgcgga tgaagtggat agtcagttta atggaatcaa aggcggtggt
     7021 ggtgcccttc tcatggaaaa ggtggtcgca acaccatcaa aagaatacat ttgggtggtg
     7081 gatgaaagca agctggtcga aaaactaggt gcttttaaat tgccagtaga agtggttcag
     7141 tatggtgcag agcaggtctt tcgtcatttt gaacgagctg gctacaaacc aagtttccgt
     7201 gaaaaagacg gccaacgttt tgtgacggat atgcagaatt ttatcattga cctcgccttg
     7261 gatgtcattg aaaatccaat tgcttttgga caagaattgg accatgtcgt tggtgttgtg
     7321 gagcatggtt tattcaacca aatggtggat aaggtcatcg ttgctggacg agatggagtt
     7381 cagatttcaa cttcaaaaaa aggaaaatag aagggggcat aagatgtcta aatttaatcg
     7441 tattcatttg gtggtactgg attctgtagg aatcggtgca gcaccagatg ctaataactt
     7501 tgtcaatgca ggggttccag atggagcttc tgacacactg ggacacattt caaaaacagt
     7561 tggtttgaat gtcccaaaca tggctaaaat aggtcttgga aatattcctc gtgaaactcc
     7621 tcttaagact gtagcagctg aaagcaatcc aactggatat gcaacaaaat tagaggaagt
     7681 atctcttggt aaggatacta tgactggaca ctgggaaatc atgggactca acattactga
     7741 gcctttcgat actttctgga acggatttcc agaagaaatc ctgacaaaaa tcgaagaatt
     7801 ctcaggacgc aaggttattc gtgaagccaa caaaccttat tcaggaacgg ctgttatcga
     7861 tgattttgga ccacgtcaga tggaaactgg agagttgatt atctatactt cagctgaccc
     7921 tgttttgcag attgctgccc acgaagatat tattcctttg gatgaattgt accgtatctg
     7981 tgaatacgct cgttcgatta cccttgagcg tcctgccctt cttggtcgca tcattgctcg
     8041 cccttatgta ggtgaaccag gtaacttcac tcgtacggca aaccgtcgtg acttggctgt
     8101 atctccattt tccccaactg ttttggataa attgaatgag gctggtatcg atacttatgc
     8161 tgtgggtaaa atcaacgata tctttaacgg tgctggtatc aaccatgaca tgggtcacaa
     8221 caagtcaaat agtcatggaa ttgatacact attgaagact atgggacttg ctgagtttga
     8281 aaaaggattc tcattcacaa acctagttga ctttgatgcc ctttacggcc atcgtcgtaa
     8341 tgctcacggt taccgtgatt gcttgcatga gtttgatgaa cgcttacctg aaattatcgc
     8401 agctatgaga gagaatgacc ttctcttgat tactgcggac catggaaatg acccaacgta
     8461 tgcaggaacg gatcacactc gggaatatat tccattgttg gcctatagcc ctgcctttaa
     8521 aggaaatggt ctcattccag taggacattt tgcagatatt tcagcgactg ttgccgataa
     8581 ctttggtgtg gaaactgcta tgattgggga aagtttctta gataaattgg tataagatga
     8641 cgcgctatgc tttgctggtg agaggtatca atgttggtgg taagaataag gtcgtcatgg
     8701 cggagcttcg tcaagaattg acaaacttgg gactggaaaa ggttgagagc tacatcaaca
     8761 gtggcaatat tttctttact tcgatagatt ccaaagccca attggttgaa aagctagaga
     8821 ctttctttgc agtccattat ccatttattc agagcttttc tttactgagt ctagaggact
     8881 ttgaggcgga acttgaaaat ctaccagctt ggtggagcag agacttggca cgaaaagatt
     8941 ttctctttta cactgagggt ttggatgtgg accaagtcat cgcgacagtt gaaagtttag
     9001 agctgaaaga tgaagtgctt tattttggaa aacttgggat tttctgaaga atcctattct
     9061 aagactgcct atcataagta cttgctgaag gtgcctttct accgccacat tactattcgt
     9121 aatgctaaaa cctttgacaa aattggtcaa atgctaaaaa aataataaag gagacacaca
     9181 atgacatttt taaacaaaat ccatgaaact gctactttcc tgaaagaaaa gggaattgca
     9241 gcccctgagt tcggtctaat ccttggatca ggacttggag aattggcaga agaaatcgaa
     9301 aatccagttg tagtagacta tgctgagatt ccaaactggg gccgttcaac agtagtcggt
     9361 catgctggta aattggtata tggtgaactg gcaggtcgca aggtcttggc tcttcaaggt
     9421 cgtttccatt tctatgaagg gaatcctctg gaagtggtga ctttcccagt tcgtgtgatg
     9481 aaagttcttg gatgtgaagg tgttattgta accaatgcag ctggcggtat cagatttggt
     9541 cctggtacct tgatggctat ctcagaccat atcaacatga cggggcaaaa tccattgatg
     9601 ggtgaaaact tggatgactt tggcccacgt ttcccagata tgtctagggc ctacacacca
     9661 gaataccgtg ccactgccca tgaagtggct aaaaaactta atatcaagct tgatgaaggt
     9721 gtctatatcg gagttactgg tccgacttat gaaacaccag cagaaattcg ttcctataag
     9781 acactgggag cagatgcagt tggtatgtct acggttcctg aagttatcgt ggcagcccac
     9841 tctgacttga aagttctggg aatttcatgt atcactaact ttgcggctgg tttccaagaa
     9901 gaactcaatc acgaagaagt tgtagaagtg actgaacgtg ttaaaggtga tttcaaaggc
     9961 ttgcttaaag cgattcttgc tgaattgtaa gaaaaaagat ttaaaagggg tagtgcctct
    10021 gtcttttcag gattgactgc ctatccggat taaagaagaa acagaggaat actatgagct
    10081 tcttcctgct cttataactg aaagaagcgg aagaataggt atgtctgatc tgatagccag
    10141 cattgtgaaa gacaagattc taggatacta gcattagctt cctagccaag cagactagta
    10201 tgataaggag agatgagaat gaattgactt tctgaatttc tcagtcttat catatatagc
    10261 acaatgagat ttcgcttgag tctgcttgta aataaacgaa aagaaagata agaaataatg
    10321 aaaattggtc aacgaattat gcgctttggc ataaaaaatt aagtatcgga gttgtatctg
    10381 ttgtagtcgg ctttgatttc tagctccagc tggaatttca gccaatgaag taaagcaaga
    10441 tgtaacatct gaagtggtaa taggtgtgct agattctaag gaggaattga aagagtcaga
    10501 aaatgatgct ccaaaactag aaactcctct tagagaggag ccaagactag ctcctcaaac
    10561 gcttccggaa gcaagtgaag ttcttgaaaa caaaagggaa gagtcaaaag tagagataac
    10621 ataaccagct caagcggatg atatccgcaa ggttgttggg gaattagcca aggatataag
    10681 tattactaag ttgtatatga caggtcattc tcttggatgt tacctagctc agattgcagc
    10741 ggttgaagct taccaaaaat atcctgattt ttataaccat gtattgagga aagtgacaac
    10801 tttcagtgct cctaaagtga ttacttccag aactgtttgg aatgctaaga atggtttctg
    10861 ggatgttggt ttggaaagtc gtaaattagc tgttagtgga aaaattaagc attatgtggt
    10921 tgataatgac aatgttgtga ctcccttgat tcataataat cgtgatattg ttacatttac
    10981 aggtaattca cgctttaaac accgttctcg tggctatttt gaaagtccaa tgaatgatat
    11041 tcctaacttt aatattggta aacaagctac cttggataaa catggttatc gtgatccgaa
    11101 attggataaa gtgcgattct ttaagaaaca ggctctacct caatcttcta gtcaaccaag
    11161 cgctgaacca atggaaaata ttgccttagg aaaacaggtt actcaaagtt cgacagcttt
    11221 cggaggagat gctagaagag ctgtggatgg caaagtcgat ggtaactatg gtcacaattc
    11281 tgtcactcat acaaacttcc aatctaagcc ttggtggcaa gtagatttgg ctaaagaaga
    11341 aaccattcgc caaatcaata tttacaaccg aacagacact gcccaggata gattggcaaa
    11401 ctttgatgtc attcttttag acagttctgg taaagaaatt gagtgaaaac gcataatatc
    11461 tcctaaagat gtgtcagcac aaattacgat taaccataaa aaagcgcgct atgttcggat
    11521 tgagctagaa ggctataatg ccctcagtct tgcagaagtt gaagttttcc gctttatagc
    11581 tacgaatgct gaaacggcga cacaagtttc taagccagtt caaccaatca gtcagactcc
    11641 tgtgaaagat aaaacattga caattcaaca cagcggagct tacattgccc gctactccat
    11701 aacttgggaa gaagttccag tagataaaga tggaaaccaa gttgttcgta gtcattcttg
    11761 ggaaggaaac ggtcgcaacc agactgcagg ttttgtcctc aacctcccaa tcaaagaaaa
    11821 tatgagaaat ctgcgagtta agattgagaa aaagacaggt ctactatgga atagatggca
    11881 aacaatctat gaaaacagac caattttagc tcaaccccac cgtaaaatta cccattgggg
    11941 tacgacattg aattccaagg tgagtgacga tgatgtcttg taatctgatg gtagaatgac
    12001 agttagtttg tctagtttat aagaaagtac tacctgagct tgaatagaac tcaggtagct
    12061 ctctatgaaa gaacaaaatt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
    12121 cgcaggttgc tcaaagcact gctttgaggt tgtagataag actgacgaag tcagtcacat
    12181 atataatcca aggcgacgtt gacgtggttt gaagagattt tcgaagagta taaacagaaa
    12241 ggtagagcgc gtgttctaat ttgaacacga gtagaaaact tttctaaaaa caaaaacgaa
    12301 aggatgggta aactgtattc gctgaactga atacgggcga ctctcctcta aatcaaaatt
    12361 aagaaagaaa ggaattgaac ccaccctaaa agcagtggga aaaagatagt tggtctagcg
    12421 agcatcgctc actgcgccca actcctattt tcccttcgct ttttgacggg tttggtatct
    12481 ttctcaatat aaaatataaa ataaagaaag gtagagcgtg tgttttgatt tgaacacgag
    12541 cggaaaactc ggaaaataga taatctgact gaaaaatcag gatttctcgt cagcttccta
    12601 attttcagtc gttttcttct cgctctttgt atcataaatt atgtctatcc atattgctgc
    12661 tcagcagggt gaaattgctg ataaaattct tcttcctggg gatcctcttc gtgctaagtt
    12721 tattgcggag aatttccttg gtgatgctgt ttgttttaac gaagtgcgta acatgtttgg
    12781 ttacactggt acttacaagg gtcaccgtgt atctgtcatg ggaactggga tgggaatgcc
    12841 atctatttcg atttatgcgc gtgagttaat cgtagactac ggtgtgaaga aattgattcg
    12901 tgtgggaact gcaggttctt tgaatgaaga ggttcatgtt cgtgaattag ttttggcgca
    12961 ggcggctgca accaactcaa acatcgttcg taatgactgg ccacagtacg attttccaca
    13021 aattgctagc tttgatttgc ttgataaagc ctaccatatt gccaaagaac ttggtatgac
    13081 tactcacgtt gggaacgttt tgtcatctga tgtcttttac tcaaattact ttgaaaagaa
    13141 tatcgagctt ggtaaatggg gagtcaaggc tgtggaaatg gaagcagcag ctctttacta
    13201 tcttgctgcc caataccatg ttgatgcgct agctatcatg accatctctg atagcttggt
    13261 caatccagac gaagacacaa ctgcagaaga acgtcaaaat accttcactg atatgatgaa
    13321 ggttggtttg gaaaccttga ttgcagaata attatagcca aaaaggaagc cctttatgaa
    13381 ttgtaggact tccttttctt atccagaaat tgatctagct ctctctgatt tcgaagaata
    13441 gtggctttat gtgaatattc ttggcaaagt ttttggtaat tttctttttg agttttgcta
    13501 cgtccatccc aaagaatcca tctgataaac tcccagtcaa agcgttcagg gcaatctgcc
    13561 gccatacttt ctctgacttt tccacggtat ttaagataac gcttaaaggc tctaaagaga
    13621 caggtcaatg gcgaaaaatt gagaaagatg atttggtcag cttcttgcat tcgttcttgg
    13681 tagtagcacc aagaataatt accatcgatg acccaagctt tatgcttggt gagaaagttt
    13741 tttatctcgg ttaacatcca ttcgtggtca ctgtcttgcc aaccaggttg aaattggagt
    13801 gtgtccatgt gcagttttgg aatggagtag tagttagata acttttctgc tagagttgac
    13861 ttaccagaac cagaatatcc gataattgtg attttcattt tctacctttt cctatttgga
    13921 gacaaaaaaa cagcctctat ggactgtttc ttatttagca agtttagctg aaagacgagc
    13981 tttatcgcgg cttgctttgt ttttgtgaat caaaccttta gtttctgctt tatcgatagc
    14041 tgagctagca gcacggaaaa gttcttcaga tgggtttgct tcgaaagctt ttatagcagt
    14101 acgcatagct gatttttgag ctgagttctt ttcgttttgt ttaacgttca attcagcgcg
    14161 tttgatagct gatttaatgt ttgccaatgt tcttacctcc atatttacta actataccat
    14221 tatatatgaa aacttacgtt ttgacaaggg aaaattattt ttttaagtaa atttcatcga
    14281 tttcatggtt cttgctttta tgaagaatca cttctgcacg atttctggtt ggttcaatat
    14341 aattttgtag atttgtgaga ttgatactgg tccagacctg atgggcaaag gcttccactt
    14401 ccccaatcgg catctgagta aaacgataat agtagctatc agggtcgttt tgggctagac
    14461 tcagcatttt caagaaacgg tccagatacc aactttcaat atcatccact ccagcatcta
    14521 catagatgga aaagtcaaag aagtcagtga tatagagacg atcgttttgt ggattttgaa
    14581 agacattgat tccctcaaca attacaaaat cagcagcttt gacactttgt ttctcttcgg
    14641 gtacgatgtc gtaaacttca tgagaataga caggaatatc tacatcttgt ccatttttga
    14701 tgcgatccaa gaagttgaga agagcttcca tattatagct ttcaggaaat cctttacgat
    14761 ttaaaatccc ctgctcaatc aaggtttgat tgggatagag aaaaccatca gttgtaacca
    14821 actcaaccgt agcatctgta aacgtacggg acagtaggat ttgaagtagg cgactggttg
    14881 tggattttcc aacggcaaca ctcccagaaa ccccaataat aaaaggttga gatttacttt
    14941 cacgttggag gaaaattcct tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct
    15001 gaatcagatg agccaagggg agatagatat ctgtaacgtc ttggagactg atttggtcat
    15061 taaaactctt gatagattcc aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta
    15121 aagattgcca agtctggcgg ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt
    15181 ttcccctaga tattttgtct atcataccat aaaaagctaa aaaaataaag cggtttcttg
    15241 aatgtggtaa gtcaatggta tatagtataa gtgatcaatt tattgatgaa ataggagata
    15301 gattctactg atttataagc ttataaaggg gactttttag ttcacaactt ataggaggtg
    15361 tactatgaaa atcttaaaac gttacatatt ggaactctgt tttattttaa gttttgcttt
    15421 accttttata aaaggagcca atgcagataa tggtagatgc tttgtggaaa cctattacgg
    15481 ttttactttt ttgatggaac atgctattgt aacagctgtc tttatctgtt cgttcttaat
    15541 tgctgtctta ctaaaaaacg atgggcgaaa tggattgcga cagagggtta tttcttccgc
    15601 atgtcactag aagatttgat acgactttgg acaagtttgg aaatcctgac acaaacgtat
    15661 cagttgggct tttatctaaa cattttgttg ggaattttgt tgataataaa gtattttaag
    15721 gttaagcaat agaaataata atctgcctga ttatagatga taaacttttt gtttttatct
    15781 ggactgtgat atttatagtt ctaaatggtt tattatttat aagtgttgaa agagattgaa
    15841 gaaaatggct tcgtgactcg ctttcttcgg tctttttcgt tttattatca atttgtaaac
    15901 gatttacaat ttgagtcaaa ttatggtaaa atagtgttat gagtaaaatg tattatgcag
    15961 aaaatcctga cgctgctcat gacattcatg agttgagagt agagttgttg ggacaaaaaa
    16021 tgaccttttt aacggatgcg ggtgttttta gcaagaaaat agttgacttt ggaagtcaac
    16081 tattgctcaa gtgtcttgag gtcaaccaag gagaaactgt ccttgatgta ggctgtggtt
    16141 acggaccttt gggtttgtcc ttagctaagg cttatggagt tcaggctact atggttgata
    16201 tcaacactcg tgccttggat ttagctcgga gaaatgctga aaaaaataat gcaaaagcga
    16261 cgattttcca gtccaacatc tatgaacaag ttgaaggaca ttttgatcat gtcatttcca
    16321 atcctcctat ccgtgcgggc aagcaagtcg ttcatgaaat cattgagaaa agtaaagatt
    16381 tcttggaaac tggtgggaat ttgacaatcg tcatccagaa aaaacaaggg gctccaagtg
    16441 ctaagtccaa gatggaggat gtgtttggta attgtgaaat ccttaaaaaa gacaaaggat
    16501 actatatcct tagaagtgtg aaagaatgag agcagttgat ttaatacaaa aaaaacgaga
    16561 cggtcaagaa ctgacttcaa gtgaaattga atggctggta gaaggctatg tgtcaggaac
    16621 tgttcctgat tatcagatgt ctgcctttgc tatggctgtt tattttaaag gaatgacgac
    16681 tcgtgaaatt tctgatttaa cgatgaatat ggttaagact gggcaagagt ttgacctgtc
    16741 agccattgat ggtgtgaaag ttgacaagca ttctactggt ggtgtcggcg ataaggtaac
    16801 cttgatttta gctcctcttg ttgctagctt cggtgtgcct gtagcaaaaa tgagtggtcg
    16861 tggtcttggc catacaggcg gaacaattga taaattggag tccattaggg gctatcaagt
    16921 agaacgtagt caagaggatt ttattcgtca ggttcaggat attggagtat ctgtcattgg
    16981 gcaatcagac cagctggtca aagcagataa gcttctctat gctcttcgtg atgtgaccgc
    17041 aactgtcgac acgattcctt tgattgcgag ttcggtgatg agcaagaaaa ttgcggcagg
    17101 ggcggatgct attttgctag acgtgactgt cggtgagggt gccttcatga agacggttga
    17161 tgaggcgcgt gagttggctc aaactatggt agatcttggt aaggttgttg gacggaagac
    17221 agtagcagtg attacggata tgagccagcc tttgggacga gcgattggaa atcgtctgga
    17281 aatacttgaa gcattggaga ttttgcaagg tcaaggacgt caggatatta cccactttat
    17341 ttgtgaattg gctcaaatta tgcttggttt ggcaaatgtt aacaagactg ttgaagaagt
    17401 tcaccaacat cttgagaatg gtcaagcact ggctaagttt gaggaaatgg tgcaagccca
    17461 aggtggagac ttggaagacc tctatcgtcc tgtaaatgta gctcatgtgg tggaaatccc
    17521 tgctcaggaa acgggtgtca tttcagctct tccagctatg gactttggtc tttatgccat
    17581 gaggctgggt gctggtcgtg cagttaagtc tgatgccttg gactatgaaa caggaattgt
    17641 ttttgaaaag aagattggag actccgttca aaagggtgaa attgttgcaa aagtatacac
    17701 aaatgaaaaa attccacctc aactagttac agatttccaa aaatgtgtta aaataagtga
    17761 tgaagtgaaa aaaatccgtg aaattgtaga aatcatctcc taaatggagg gaaaaccgaa
    17821 atgaaattaa ataaatatat agatcatacg cttttaaaac aagatgcaaa gaaaaaacaa
    17881 attgatagtt tgttgtctga ggctagagag tatggctttg ccagtgtttg cgttaatcca
    17941 acctgggttg aacatgctaa aaaagggctt gaaggcacag atgttaaggt ttgcacggta
    18001 gtaggtttcc ctttgggagc aacaacttca gccgtgaaag catttgagac aaaagaagct
    18061 atccaaaatg gtgcagatga gattgatatg gtgatcaatg ttggagctct caaatcaggt
    18121 aatttagcct tggttgagtc agatattcgc gcagtagtgg aagcaagtgg tgataagtta
    18181 gtgaaagtca ttattgaagc ttgccttctg acagaccaag aaaaagttgt tgtttgccaa
    18241 ttggcccaaa aagctggggc tgactttgtc aaaacatcta ctggcttttc aactggtggt
    18301 gctacgatag cagatgttac attaatgcgt gaaacagttg gatctgatat gggagtcaag
    18361 gctgctggtg gagctcgttc ttatgcagat gctcttgcct ttgtcgaagc aggtgcgacc
    18421 cgtatcggaa cgtcagctgg ggtagctatt ttaaaaggag aattggcaga tggcgactac
    18481 tgagttgatt gaactggcaa ttgaaaccag caaacatgcc tatgtcccct attctcactt
    18541 tcctatcgga gcagttttag tagccaaaga cggaaatgtt tacacgggag tgaatatcga
    18601 aaatgctagc tatcctttga ccaattgcgg tgagagaaca gctattttta aggctatatc
    18661 tgaaggccaa agagaatttt cagaattgat tgtctatggt caaactgaaa aaccgatttc
    18721 accatgtggt gcttgtcgcc aagtaatggt cgaatttttt gaacaagatt taaaagtgac
    18781 cttagtcgca aaagataaat cgacggtcga gatgacggtc ggggagttac ttccatattc
    18841 ttttacagac ttaaattagt ctgagtcgct ctttgagtgg caagggtctt tgtgaccaat
    18901 caatccatac ttgcaacatc gttgcacatc ttatttagga ggttcagtaa tgaacaagaa
    18961 acaatggcta ggtcttggcc tagttgcagt ggcagcagtt ggacttgctg catgtggtaa
    19021 ccgctcttct cgtaacgcag cttcatcttc tgatgtgaag acaaaagcag caatcgtcac
    19081 tgatactggt ggtgttgatg acaaatcatt caaccaatca gcttgggaag gtttgcaggc
    19141 ttggggtaaa gaacacaatc tttcaaaaga taacggtttc acttacttcc aatcaacaag
    19201 tgaagctgac tacgctaaca acttgcaaca agcggctgga agttacaacc taatctttgg
    19261 tgttggtttt gcccttcaca atgcagttga agaagcagct aaagaacaca ctgacttgaa
    19321 ctatgtcttg attgatgatg tgattaaaga ccaaaagaat gttgcgagcg taactttcgc
    19381 tgataatgag tcaggttacc ttgcaggtgt ggctgcagca aaaacaacta agacaaaaca
    19441 agttggtttt gtaggtggta tcgaatctga agttatctct cgttttgaag caggattcaa
    19501 ggctggtgtt gcgtcagtag acccatctat caaagtccaa gttgactacg ctggttcatt
    19561 tggtgatgcg gctaaaggta aaacaattgc agccgcacaa tacgcagccg gtgcagatat
    19621 tgtttaccaa gtagctggtg gtacaggtgc aggtgtcttt gcagaggcaa aatctctcaa
    19681 cgaaagccgt cctgaaaatg aaaaagtttg ggttatcggt gttgaccgtg accaagaagc
    19741 agaaggtaaa tacacttcta aagatggcaa agaatcaaac tttgttcttg tatctacttt
    19801 gaaacaagtt ggtacaactg taaaagatat ttctaacaag gcagaaaaag gagaattccc
    19861 tggcggtcaa gtgatcgttt actcattgaa ggataaaggg gttgacttgg cagtaacaaa
    19921 cctttcagaa gaaggtaaaa aagctgtcga agatgcaaaa gctaaaatcc ttgatggaag
    19981 cgtaaaagtt cctgaaaaat aatggatgga agtcatttct taggaagcgg ccaagggccg
    20041 cttttttaag agttgagaca aagtcatttt gtctcagtaa agcttgctac tagacaaact
    20101 agcaagtttt attgaaataa aataagactc tgaaaggaag agcacatggc acacgaaaat
    20161 gtcattgaga tgcgtgatat taccaaggtg tttggtggat ttgttgccaa cgacaaaatc
    20221 aacttgcacc tacgaaaagg tgaaattcat gcacttttag gagaaaatgg ggctggtaag
    20281 tccacgctaa tgaacatgtt agcaggcctt cttgaaccaa ctagtggtga aatcgcggtc
    20341 aacggtcaag ttgtcaatct cgactcccca tctaaagcag ctagcttggg aatcgggatg
    20401 gttcaccagc actttatgtt ggttgaagcc ttcacagtgg ctgaaaacat cattttaggt
    20461 agtgaattga ctaaaaatgg tgtgctagat atcgctggag ctagcaaaga aatcaaggct
    20521 ctttctgaac gttatggctt agctgttgac ccttctgcca aggtagcaga tatctcagtt
    20581 ggagcccaac aacgtgtaga aattttaaaa acactttata ggggggctga tatccttatc
    20641 tttgacgaac caacggctgt tttgactcca tcagaaattg atgagttgat ggctattatg
    20701 aaaaatcttg tcaaagaagg aaaatcaatt atcttgatta cccacaaatt ggatgaaatt
    20761 cgcgcagttt ctgaccgtgt tacagttatc cgtcgtggga aatcaattga aaccgttgaa
    20821 attgcagggg ctaccaatgc tgatttggcg gaaatgatgg taggacgttc tgtttccttt
    20881 aaaacagaga agcaagcctc taaaccaaaa gaagtggttt tgtctatcaa agatttggtg
    20941 gtcaatgaaa accgtggtgt tccagctgtt aaaaatctgt ccttggatgt tcgtgctgga
    21001 gagattgttg gtattgcggg gattgatgga aatggtcagt ctgaactgat tcaagccatt
    21061 acaggtcttc gtaaggttga atctggtagc attgagctaa aaggagattc aattgtaggc
    21121 ttgcacccac gtcagattac agaactaagt attgggcacg ttccagaaga ccgtcaccgt
    21181 gatggcttga ttttggaaat gatgatatct gaaaatattg cccttcaaac ctactataaa
    21241 gaaccacata gtaaaaatgg aattttgaat tattcaaata ttacttctta tgctaaaaag
    21301 ctgatggaag agtttgatgt tcgcgctgcc agtgaattag ttcctgcagc tgcactctca
    21361 ggaggaaatc aacaaaaagc aattattgct cgtgaaattg atcgagatcc tgatctcctt
    21421 atcgttagcc agccaactcg tgggttggat gtcggtgcca ttgagtatat ccacaaacgc
    21481 ttgattgaag agcgtgataa tggcaaggct gtccttgttg tcagctttga attggatgag
    21541 attttaaacg tctcagaccg tattgccgtt atccacgatg gtaagattca aggtattgta
    21601 tcaccagaaa caaccaataa acaagaactt ggtgtcttga tggctggtgg aaacttggga
    21661 aaggagaaga gtgatgtcta aaaaattaca acaaatttcg gttcccttga tttctgtatt
    21721 tctaggaatt ttactcggag ccattgtcat gtggatcttc ggttatgatg ctatttgggg
    21781 ctacgaagaa ttgttctata cagcctttgg cagtctgcgt gggattggag aaatcttccg
    21841 tgctatgggt cctctggtct tgattggtct tggttttgcg gttgccagtc gagctggttt
    21901 ctttaacgtc ggacttcctg gtcaggcttt ggcaggttgg attctcagtg gttggtttgc
    21961 cctgtcgcat ccagatatgc cccgtccctt gatgattcta gcaaccatcg tgattgcctt
    22021 gattgctggt gggattgtcg gagcgattcc aggtattctt agggcctatc tagggacgtc
    22081 agaggttatt gtaaccatca tgatgaacta cattgtcttg tatgtaggga atgcctttat
    22141 ccatgctttc cctaaagact tcatgcaaag tacagattcg accattcgtg ttggggctaa
    22201 tgcaacctat cagacacctt ggttggctga gttgactggt aactcacgga tgaatattgg
    22261 tattttcttt gccatcattg ccgttgcagt tatttggttc atgctcaaga aaacaactct
    22321 tggttttgaa atccgtgcag ttggtcttaa tccacatgct tcagaatatg ctggtatttc
    22381 tgccaagcgg actattatcc tatctatgat tatttcaggt gccttggcag gtcttggtgg
    22441 agctgttgaa ggtttgggaa ccttccagaa cgtctatgtt caaggttcgt cattagctat
    22501 cggatttaac ggaatggcgg ttagtttgct tgcggccaac tcaccaattg gtatactctt
    22561 tgcagccttc ctatttggcg ttctccaagt tggggctcct ggtatgaatg cggcgcaggt
    22621 accatctgag cttgtcagca ttgtaacagc gtctattatc ttctttgtca gtgttcatta
    22681 ccttatcgaa cgctttgtca aaccgaaaaa acaagttaaa ggaggtaagt aaagatgtct
    22741 attataacct tgctccccct cttggtgtct tctatgctga tttactcagc acctctcatc
    22801 tttacaagta tcggtggtgt tttctctgaa cgtggtggtg tggtaaacgt tggccttgaa
    22861 ggaattatgg ttatgggtgc cttttctgga gttgtcttta accttgaatt tgcagaacaa
    22921 tttggagcag caactccatg gctatccttg cttgtagcag gattggttgg tagtgttttc
    22981 tctatcatcc acgcagcagc gacggttcat ttccgtgcag accatgttgt cagcggtacg
    23041 gtattgaact tgatggcgcc tgccttggct gttttcttag ttaaagttct ttataacaaa
    23101 ggacaaaccg acaacctaag tcaaactttt ggacgctttg atttcccagt cttggcaaat
    23161 atcccagtga ttggtgatat cttcttcaag tcaactagtc tacttggtta tctggcgatt
    23221 gccttctcat tccttgcttg gtttattctc tttaagactc aatttggtct tcgtctccgc
    23281 tctgtcggtg aacatcctca agcagcggat accttgggaa tcaacgtcta caagatgaga
    23341 tatttaggga ttattatttc aggttttcta ggtggaattg gcggagcgat ttatgcgcaa
    23401 tcaatctcag ttaacttctc agtgacaact attgttggac ctggatttat cgcccttgct
    23461 gcgatgatct ttgggaaatg gaatccaatc ggtgctatgc tttctagtct cttctttgga
    23521 ctttcacaaa gtttggctgt tatcggttct caattgccgt ttctacaagg agtgccagcg
    23581 gtttatcttc aaattgcacc ttatgttttg acaattcttg tcttagcagc cttctttgga
    23641 aaagcagtcg caccaaaagc agatggtatc aactacatca aatcaaaata agcatacaaa
    23701 aaaacgtcag tccaatgact gaactacccc ccaaaagtta gacagaaaaa atctaacttt
    23761 tggggtgttt ttattatgaa actaacttat gatgataaag ttcagatcta tgaacttaga
    23821 aaacaaggat atagcttaga gaaactttca aataaatttg ggataaataa ttctaatctt
    23881 aggtacatga ttaaattgat tgatcgttac ggaatagagt tcgtcaaaaa aggaaaaaat
    23941 cgttactatt ctcctgattt aaaacaagaa atgagtaata aagtctgaca tgaaggctgg
    24001 actaaagata gagtttctct tgaatacggc ctcccaagtc gtacgatact tcttaactgg
    24061 ctagcacaat acaggaaaaa cgggtatact attgttgaga aaacaaaagg gagagtacct
    24121 gagagcggag aatgccatcc taaaaaagtt aagagaactc cgattgaagg aggaaaaaga
    24181 gaaagaagaa agacagaaat tgttcaagaa ttaatgactg agttttcgtt agatcttctt
    24241 ctaaaatcca ttaaactagc tcgttggacc tactactatc acttgaaaca gctagacaaa
    24301 acagataagg accaagagct taaagctgaa attcaatcca tttttatcga acacaaagga
    24361 aattatgctt atcgccgggt tcatttagaa ctaagaaatc gtgcttatct ggtaaatcat
    24421 aaaagagttc aaggcttgat gaaagtactc aatttacaag ctaaaatgcg acagaaacga
    24481 aaatattctt ctcataaagg agacgttagc aagaaggcag agaatctcat tcaaggccaa
    24541 tttgaaggct ctaaaacaat ggaaaagtgc tacacagatg tgacagaatt tgccattcca
    24601 gcaagtactc aaaagcttta cttatcacca gttttagatg gctttaacag cgaaattatt
    24661 gcttttaatc tttcttgttc gcctaattta gaacaagtac aaacaatgtt ggaacaggca
    24721 ttcaaagaga agcactacga gaatacgatt ctccatagtg accaaggctg gcaatatcaa
    24781 cacgattctt atcatcggtt cctagagagt aagggaattc aagcatctat gtcacgcaag
    24841 ggaaacagcc aagacaatgg tatgatggag tccttctttg ggattctgaa atcggaaatg
    24901 ttttatggct atgagaaaac atttaaatca cttaatcaat tggaacaagc tattgtagac
    24961 tatattgatt actacaacaa taaacgaatt aaggtaaaac taaaaggact tagccttgtg
    25021 caatacagaa ctaaatcctt tggataaatt atttgtctaa ctgtttgggg gcagtacaga
    25081 actggcgttt tattttttag gatcttgatg ggttaggttc aatccccaag ggaccaaatt
    25141 ttcagtttta tttttgatac gagctatatt gtccttatga cgaatgataa tcaaactagc
    25201 aagtgctaag ataatagcga tgaagagaga gtcatagtta ctcaggataa aaccaaaaag
    25261 tggaaagagc agaaccccga taacagccgc gatcgatgct gtgacactag acagtgaaat
    25321 catactgcca agatagagag ctccaaagaa gataatcgca aggtagagac agaagatagg
    25381 cgcaaatccg aaaatcactc cagcactggt tgcgacagcc ttaccacctt taaatcctgc
    25441 aaagataggg aaggtatggc cgataacagc caaaagtcca aagatgagag gagaaacgcc
    25501 ttgtagatga aaaataatcg gaagcagcgt tgctagggtt cctttgaaaa agtcaatcac
    25561 aaaggttgcc ataccagctt tcttacctaa aatgcggaag gtgttggtcg ttccagtgtt
    25621 accagaacca tgctcgcgta gattgatttg aaagaatact tgtccaatcc agagaccaga
    25681 tggaatcgaa cccagcagat aggctaggat taataaaact attgtaatca tactcctatt
    25741 atatcatgaa ttgggaaaga aaagcagaga atctctgcta aaattgtcac atcggagaaa
    25801 gaaaaatttt gcaaaatcct tggaaaacct gtagaatagt aaagatgaac gaataggagg
    25861 ttccttgtgt caaaaaagga aatcaatatt aacaattata atgatgatgc tattcaggtg
    25921 ctagaagggt tggatgcggt ccgaaaacgt ccagggatgt atattggatc gaccgatggc
    25981 gctggtcttc atcacctagt ttgggaaatc gttgataatg cagtcgatga agccttgtct
    26041 gggtttggtg atcgtattga tgtaactatc aataaagacg gtagtctaac ggttcaagac
    26101 catggacgtg ggatgccgac aggtatgcac gctatgggaa ttccaactgt tgaggttatc
    26161 tttaccattc ttcatgccgg agggaaattc ggtcaaggtg gctataagac atcaggtgga
    26221 cttcacggag tgggttcttc cgttgttaac gccctttcta gctggttaga agttgaaatt
    26281 acccgtgatg gcgcagttta caagcaacgt tttgaaaatg gtggaaaacc tgtcacgact
    26341 ttgaagaaaa tcggtacagc acccaagtct aaaacaggca ccaaagttac ttttatgcct
    26401 gacgcgacta tcttttctac gacagatttc aagtacaata ccatttcaga gcgccttaat
    26461 gaatcagcct ttctcttgaa aaatgtgacc ttgtctttaa cggacaagcg aacagatgaa
    26521 gcgattgagt tccactatga gaatggagta caagattttg tttcttatct caacgaagat
    26581 aaggaaatct tgacgccagt tctttacttt gaaggggaag acaatggttt tcaagtggaa
    26641 gtagccctcc agtacaatga cggattctca gataacattc tatcctttgt caataacgtt
    26701 cgcaccaagg acggtggaac gcacgagaca ggactcaagt ctgccattac caaggtcatg
    26761 aatgactatg cacgtaaaac aggtcttctc aaggaaaaag ataaaaacct tgaaggttca
    26821 gactatcgtg agggactagc ggccgttctt tctatcttag ttcctgaaga acacttgcag
    26881 tttgaaggac agaccaagga taaactagga agccccctag ctcgcccagt tgtggatgga
    26941 atagtggctg ataagttgac ctttttcctt atggaaaatg gggaattagc ttctaacctc
    27001 atccgcaagg ctatcaaggc tcgtgatgct cgtgaagcag cacgtaaggc gcgtgatgag
    27061 agccgaaatg ggaagaaaaa caagaaagat aagggcttgt tgtctgggaa attgacccca
    27121 gcccaatcta agaatcctgc taagaatgaa ctctatctag ttgaggggga ctctgccggt
    27181 ggttctgcca aacaaggtcg tgaccgcaag ttccaggcta ttctacctct tcgtggtaag
    27241 gttgtcaata cagccaaggc caagatggcg gatatcctca aaaatgaaga gatcaatacc
    27301 atgatttata ccattggtgc gggtgttgga gcagacttct ctattgaaga tgccaactat
    27361 gataagatca ttatcatgac cgatgcggat accgacggtg cccatatcca gaccttgctc
    27421 ttgacatttt tctaccgtta catgcgtccg ctagtcgagg caggtcatgt ctatattgcc
    27481 ctcccacctc tttacaagat gtccaaaggt aaaggcaaga aagaagaagt ggcctacgct
    27541 tggacggacg gagaactaga agaactccgt aaacagttcg gtaaaggcgc taccctccaa
    27601 cgatacaaag gacttggtga gatgaatgcg gaccagctct gggaaacaac catgaaccca
    27661 gaaacacgta ccctcatccg tgtcacaatt gaagatttag cgcgcgccga acgccgcgtc
    27721 aatgttctca tgggagataa ggtagaacca cgccgtaaat ggattgaaga taatgtcaag
    27781 tttacgctag aagaagcgac agtgttttaa tgaaagaaaa taatatgtta gtaaactgga
    27841 aattagagtc ggatgtgaat gactatgtga aaaagcagtt tgaaaatctt ggtttgaaaa
    27901 aattgcagga ttattaatga agaatctgct atgagtgctt atctcaaaga ggcgtttaag
    27961 ggagcgacta agacacaaac taagactaat tttggaaaac cagattttca tattgaaaaa
    28021 tacaaacagg atagtttggt tacttatcgt aactgaacac gggaggaatt cccgtaaaat
    28081 atcttttact gcataaaaac ctactctaca ttctttgaaa ggagttgaac acgccctaga
    28141 tactgtgtga aaaagataaa ttctcttgtg agtttgctta cttcaagaat tttctatttt
    28201 cacttggtat tttatgggct ttgtatctta tgtctaacat tcaaaatatg tccctggagg
    28261 acatcatggg agagcgcttt ggtcgctact ccaagtacat tattcaagac cgggctttgc
    28321 cagatattcg tgatgggttg aagccggttc agcgccgtat tctttattct atgaataagg
    28381 atagcaatac ttttgacaag agctaccgta agtcggccaa gtcagtcggg aacatcatgg
    28441 ggaatttcca cccacacggg gattcttcta tctatgatgc catggttcgt atgtcacaga
    28501 actggaaaaa tcgtgagatt ctagttgaaa tgcacggtaa taacggttct atggacggag
    28561 atcctcctgc ggctatgcgt tatactgagg cacgtttgtc tgaaattgca ggctaccttc
    28621 ttcaggatat cgagaaaaag acagttcctt ttgcatggaa ctttgacgat acggagaaag
    28681 aaccaacggt cttgccagca gcctttccaa acctcttggt caatggttcg actgggattt
    28741 cggctggtta tgccacagac attcctcccc ataatttagc tgaggtcata gatgctgcag
    28801 tttacatgat tgaccaccca actgcaaaga ttgataaact catggaattc ttgcctggac
    28861 cagacttccc tacaggggct attattcagg gtcgtgatga aatcaagaaa gcttatgaga
    28921 ctgggaaagg gcgcgtggtt gttcgttcca agactgaaat tgaaaagcta aaaggtggta
    28981 aggaacaaat cgttattact gagattcctt atgaaatcaa taaggccaat ctagtcaaga
    29041 aaatcgatga tgttcgtgtt aataacaagg tagctgggat tgctgaggtt cgtgatgagt
    29101 ctgaccgtga tggtcttcgt atcgctatcg aacttaagaa agacgctaat actgagcttg
    29161 ttctcaacta cttatttaag tacaccgacc tacaaatcaa ctacaacttt aatatggtgg
    29221 cgattgacaa tttcacacct cgtcaggttg ggattgttcc aatcctgtct agctatatcg
    29281 ctcaccgtcg agaagtgatt ttggcgcgtt cacgctttga caaagaaaag gctgagaaac
    29341 gtctccatat cgtcgaaggt ttgattcgtg tgatttcgat tttggatgaa gtcattgctc
    29401 ttatccgtgc ttctgagaat aaggcggacg ccaaggaaaa cctcaaagtt agctatgatt
    29461 ttacggaaga acaggctgag gctatcgtaa ctttgcaact gtaccgtttg accaataccg
    29521 atgtggttgt cttgcaggaa gaagaagcag agcttcgtga gaagattgct atgctggcgg
    29581 ctattatcgg tgatgaaagg actatgtaca atctcatgaa gaaagaactt cgtgaggtca
    29641 agaagaaatt tgcaactcct cgtttgagtt ctttagaaga tactgcgaaa gcaattgaga
    29701 ttgatacagc tagtcttatc gctgaggaag atacctacgt cagcgtgacc aaggcaggtt
    29761 acatcaagcg taccagtcca cgttcctttg cggcttccac cttggaagaa attggcaagc
    29821 gtgatgatga ccgtttgatt tttgttcaat ctgccaagac aacccagcac ctcttgatgt
    29881 tcacaagtct tggaaatgtc atctacagac caatccatga gttggcagat attcgttgga
    29941 aggacatcgg agagcatctg agccaaacca tcacaaactt tgaaacgaat gaagaaatcc
    30001 tttatgtgga agtactggat cagtttgacg atgcgacaac ctactttgca gtgactcgcc
    30061 ttggtcaaat caaacgggta gagcgaaaag aattcactcc atggcggacc tatagatcta
    30121 agtctgtcaa gtatgctaag ctcaaagacg atacagatca gattgtagca gtggctccga
    30181 ttaaactaga tgatgttgtc ttggttagtc aaaatggtta tgccctgcgt ttcaatatcg
    30241 aagaggttcc ggttgtcggt gctaaggcag caggtgtcaa ggctatgaat ttgaaagaag
    30301 atgatgtcct ccaatctggc tttatctgta atacttcgtc cttctacctc ttgacccagc
    30361 gtggaagctt gaaacgtgtt tccattgagg aaattctagc aaccagccgt gccaaacgag
    30421 gattacaagt cttgcgtgag ttgaaaaaca aaccgcatcg tgtcttcttg gcaggagcag
    30481 ttgcagagca aggatttgtt ggcgatttct tcagtacgga agtggatgtg aacgaccaaa
    30541 ctctgcttgt ccaatccaat aaaggaacaa tctatgaaag ccgattgcaa gacttgaact
    30601 tgtcagaacg cactagcaat ggaagcttca tttctgacac gatttcagat gaagaagttt
    30661 ttgacgctta tcttcaggaa gtagttactg aagataaata agtgaaatga agaatcagtt
    30721 ctaagagctg gtttttattg gagaaatttt ctgaaaatta caaaatatac ttgctatttt
    30781 agaaaaatag tgtagaatat aagaaatagg tttttagaat aaggagtgga atatgacagt
    30841 aacgattgat tgggaaaacc tcggtttttc ctatatgaaa ttaccttatc gctatcttgc
    30901 tcatttcaaa aatggacaat gggatcaagg agagcttaca gaggatgcaa ctttgcatat
    30961 ttcagagtct tctccaagtc ttcactatgg acaacaagca tttgaaggtt tgaaagctta
    31021 tcgtactaag gatggcagtg ttcaactgtt ccgtcctgat gaaaatgcta aacgtctgca
    31081 acgtacatgt gaccgtctct tgatgccaca agttccgaca gacatgtttg tagaagcttg
    31141 taaagcagtt gtccgtgcga atgaagaata cgtaccacca tacggaacag gtggaacctt
    31201 atatcttcgc cctcttttga ttggtgtcgg agatattatc ggggtaaaac cggcagaaga
    31261 gtacattttc accatctttg ctatgccagt tggaaattac tttaaaggtg gtttggtccc
    31321 aaccaacttc ttgattcagg atgagtacga ccgtgcagca ccaaatggta caggtgcggc
    31381 taaggttggt ggaaactatg ctgcaagtct cttaccagga aaaatggcca agtcacgtca
    31441 tttctcagat gttatctatc tggacccatc aactcataca aagattgaag aagtcggatc
    31501 agctaacttc tttggaatta cagctgataa tgaatttgta acaccattga gtccatctat
    31561 cttgccatct attaccaagt attccttgct ttatttggca gaacatcgct tgggattaac
    31621 tcctattgag ggtgatgttc caattgataa tcttgaccgt tttgtagagg caggtgcctg
    31681 tggtacagca gcggttattt ctccaattgg aggtattcaa catggtgatg atttccatgt
    31741 attctatagt gaaacagaag taggtcctgt gacgcgtaaa ttatataatg aattgacggg
    31801 tattcagttt ggcgatattg aagcgccaga aggttggatt gtaaaagtag attaaaataa
    31861 accaaaggag attttttatg aaatagaaaa agtggctctt aacagcagga gtggtcctga
    31921 gcacgtcagc tattttagtg gcttgtggaa aaactgataa agaagcagat gcaccgacaa
    31981 cattttctta tgtctatgca gtagatccag catcattggg ctacagtata gcgactcgaa
    32041 catcgaggac agacgttatt ggaaatgtta ttgatggttt gatggaaaat gataaatacg
    32101 gcaatgttgc tccttctcaa aaagactatg atttgaatag tacaggatgg gctccaagct
    32161 atcaagatcc agcgtcttac ttgaatatta tggatccaaa atctggttct gccatgaaac
    32221 accttggtat tacgaaagga aaagataagg atgttgtagc taaacctggt ttggataaat
    32281 ataagaaatt gttagaagat gctgtttctg agaccactga cctagagaag agatatgaaa
    32341 aatatgccaa agctcaagct tggtcgacag atagttcatt attgatgcca acagcttcat
    32401 ctggtggttc tccagttgta agtaacgtag taccattctc aaaaccatac tcacaagttg
    32461 gtattaaggg ggaaccatat atctttaaag gaatgaaatt gcaaaaagat attgttacaa
    32521 caaaagaata taacgaggtt tttaaaaaat ggcaaaaaga aaaattggaa tccaatagca
    32581 aataccaaaa agaactagaa aaatacatta aataaggaat ggtattgatc ttgataaaat
    32641 ttttaaaata ctgtcatttt gaatataaag gagtttgata tggagtggat tagattaata
    32701 ggaatagcaa tcattgttgt gggttttatt ttaaaatttg atacaattgc aacagtagtc
    32761 ttagctggtt tggttacagc tttagtttca ggtgtttctc tcgttgaatt tttggagatt
    32821 ttgggaaaag aatttagcaa tcagcgagtg ctcacgattt ttatggttac cttgcctctt
    32881 gtggggctgt cagaaacctt tggactcaag caacgatcaa tcgatttgat tcgaaagatt
    32941 aaaggtctga cagttggaaa cttctataca gtttattttt ttattcgaga gttagctggt
    33001 ttcttttcaa ttcgtctagg aggacaccct cagtttgtca gacctttggt tcaacctatg
    33061 ggagaagcag ctgcagagtc tcaattaggt agaaagttaa cagaggttga agatgagaca
    33121 ataaaagcgc gtgcggctgc gaatgaaaat tttggaaatt tctttgctca aaatacgttt
    33181 gtaggtgctg ggggagtcct cttgataggg ggaacattag atcagttagg ctatgaaagc
    33241 aattatgcag ggattgcttc tacatctatt attgttgctg ttataacact tattgtagtg
    33301 gggatttaca attatttatt tgataaaaaa ttgatatcaa aaaagactag gggaggagaa
    33361 caaaaatgac agagttggca aagcaactat tagagttgac ctatattgtg attggttgtc
    33421 aatttctcca tacagcctat tgtagttata aagataaaac aaacccagtt cgacttggga
    33481 catctgcatt ttggactcta ttgtctatta cgtttatagg tggttcctat atgccaaata
    33541 tgagtattgg tattattgta atcctattat cgctgttaac attgtttaag caagtccgta
    33601 tcggaacctt gccatcctta gatgaaatga aagccaatat tgaatctaac aggttgaaaa
    33661 ataaaatttt tattccagtt atgctgatgg caatacttgc gttggtctta gcgcaaatga
    33721 ttccagaatt tagcaagatt tcgattagcc ttgccgcctt gtttgctaca atttctgttc
    33781 ttgtgattac caatagtcac cctaagagtc tgttatcaga aaataatcga atgactcagc
    33841 aagtttcaac aagtggtatt gttcctcaat tattaggggc tttgggggct atttttactg
    33901 tagcaggtgt tggtgatgtt atctctcatc tgattagcgg tattgttcct tcagatagtc
    33961 gctttatagg agttttggcc tatgttcttg gaatggttct attcacaatg attatgggaa
    34021 atgcttttgc agcattcacc gttattacag caggtgttgg agttcccttt gtatttgctc
    34081 tgggagctaa tccaattgtg gctggtgctc ttgccatgac agcaggttat tgtgggacct
    34141 tattgacccc aatggctgct aattttaacg ctctaccagc agcattgatg gatatgaaag
    34201 atcagaatgg cgttataaag gctcaagcag gtgttgctct agtaatgatt gttattcaca
    34261 tattcttaat gtactttctc gcattttagt aaaggaaaat aaaatgaaaa tattggttac
    34321 aggttttaat ccttttggag gtgaaaagat taatccagct ttggaggctg taaaattatt
    34381 accatctgag attaatgggg ctgaagttcg ctgggtagaa attccaacgg ttttttataa
    34441 gtcgtcagaa gttttagagg cagaaatatt acgatatcaa ccagatgctg tactttgtat
    34501 tggacaagca ggcggcagga ccggcttaac acctgaacga gtggctatta atcaagatga
    34561 tgctcgcata cctgataacg aaggcaatca accaattgat acaccgattc gtattgatgg
    34621 agcatcggcc tattttagta gtttacctat caaagcgatg gtacaagcta tcaaaaaaca
    34681 gggacttccg gcagttgtat ccaatagtgc aggaaccttt gtttgcaatc atttgatgta
    34741 ccaagctctt tatttagtgg ataaaaaatt ccctaatatg agagcaggtt tcatgcatat
    34801 tccatatatg atggaacaag tagtaaataa gccgaatact gcaggaatga gtctatgtga
    34861 tattgtaaga ggcatagagg tagctattga agctattgta gactacaaag ataaggattt
    34921 gcagttagta ggcggtgaga ctcactgata acctaaaaag gatagtcaat tatgcttgtt
    34981 tactaactat tagctatgct aaatcgattg aggttgttta cataaaactc tatatcagag
    35041 aagcctgata tagagttttt tcttgctagt tttaggattt tcttgtaaaa tagaaaaagt
    35101 gaagagaggt atgaaatgag caagaaagat aaaaaaatcg aaattcaagt agcggatgcc
    35161 aaagttaatg ttggtaaaga cagttttgaa ggttatacat tgactatcgg taaaaaagtt
    35221 atcggagaaa ttgccgaatt agacggacaa tttgccatta taaagaatgg gaatgtcgat
    35281 agtttttata aaaaattgga aaaagctgtg gaaattttga ttgaaaatta taatttagca
    35341 aaataagtct tgtttttttg aaattttcat gatataatag tccatgttga ttgtaggaga
    35401 gatagcgaag aggctaaacg cggcggactg taaatccgct ccttcgggtt cgggggttcg
    35461 aatccctctc tctccatttc attaatgggg tatagccaag cggtaaggca agggactttg
    35521 actccctcat gcgttggttc gaatccagct accccagttc ttaggtaata atcaagataa
    35581 aaagcaaaat atcttagggt attttatttt tataattgaa agacgtgaat gatatgaaca
    35641 tgtccttgcg ggtgcttagg aaaaaaatta taagtatgtc aagtttaaga aaaacttgat
    35701 tgttggagga ttttttagat gaacgaattt gaagatttgc taaatagcgt tagtcaagtt
    35761 gagactggtg atgttgttag tgctgaagta ttgacagttg atgcgactca agctaacgtt
    35821 gcaatctctg gaactggtgt tgaaggtgtc ttgactcttc gcgaattgac aaacgatcgt
    35881 gatgcagata tcaatgactt tgttaaagta ggagaagtat tggatgttct tgtacttcgt
    35941 caagtagttg gtaaagatac tgatacagtt acataccttg tatctaaaaa acgccttgaa
    36001 gctcgcaaag catgggacaa acttgttggt cgcgaagaag aagttgttac tgttaaagga
    36061 acgcgtgccg ttaaaggtgg actttcagta gaatttgaag gtgttcgtgg atttatccca
    36121 gcttcaatgt tggatactcg tttcgtacgt aacgctgagc gttttgtagg tcaagaattt
    36181 gatactaaaa tcaaagaagt taacgctaaa gaaaaccgct tcatcctttc acgtcgtgaa
    36241 gttgttgaag cagctactgc agcagctcgc gctgaagtat tcggtaaatt ggctgttggt
    36301 gatgttgtaa ctggtaaagt tgctcgtatc acaagcttcg gcgctttcat cgaccttggt
    36361 ggtgttgacg gattggttca cttgactgaa ttgtcacatg aacgtaacgt atcaccaaaa
    36421 tcagttgtaa ctgttggtga agaaattgaa gtgaaaatcc ttgatcttaa cgaagaagaa
    36481 ggacgtgtat cactttcact taaagcaaca gtaccaggac catgggatgg cgttgagcaa
    36541 aaattggcta aaggtgatgt agtagaagga acagttaaac gtttgactga cttcggtgca
    36601 tttgttgaag tattgccagg tatcgatgga cttgttcacg tatcacaaat ttcacacaaa
    36661 cggattgaaa atccaaaaga agctcttaaa gttggtcaag aagttcaagt taaagttctt
    36721 gaagttaacg cagatgcaga acgcgtatca ctttctatta aagctcttga agaacgtcca
    36781 gcccaagaag aaggacaaaa agaagaaaaa cgtgctgctc gtccacgtcg tccaagacgt
    36841 caagaaaagc gtgatttcga acttccagaa acacaaacag gattttcaat ggctgatttg
    36901 tttggtgata tcgaacttta atcaaattga aaattcacaa aatcctttgt ttactaaaca
    36961 agggattttt cggctctttg tcaactgtag tgggttgaaa aaagctaagc tcgagaaagg
    37021 acaaatttcg tcctttcttt tttgatgttc aaagtgataa caatccgttt tttgaaattt
    37081 tcaaagtttc gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt attggtcgct
    37141 tccagtttgg cattagaata gtgtagttga agggcgttga taatcttttc cttatctttg
    37201 aagaaggttt taaagacagt ctgaaaaata ggatgaactt gcttcagatt gtcctcaata
    37261 agtccgaaaa gtttctctgg ttccttattc tggaagtgaa aaagcaagag ctgatagtgg
    37321 tgtttcaagt tttgtgaata gctcaaaagc ttgtctaaaa tctctttatt ggttaagtgc
    37381 atacgaaaag taggacgata aaatcgctta tcactcagtt tacggctatc ctgttgaatg
    37441 agtttccagt agcgcttgat agccttgtat tcatgggatt ttcgatgaaa ctgattcatg
    37501 atttggacat gcacacgact catagcacgg ctaagatgtt gtacaatgtg aaagcgatca
    37561 agaacgattt tagcattcgg gagtgaaaca gcctgggaga ctgtttcagc ctgagcctag
    37621 aaatttgaaa gcgaagctgt ttagccaagt catagtaagg actaaacata tccatagtaa
    37681 tgattttgac gcgacatcgg acggctctat catatttaag aaagtgatct cggatgacag
    37741 cttgtgttct accctcaaga acagtgatga tatcgagctt ttcaaaatct tgcgcaataa
    37801 agctcatctc catctcccga ttgaaacagt cactccccgg actgtttcaa c
//
LOCUS       DAVHSL010000016        36149 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000016 DAVHSL010000000
VERSION     DAVHSL010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.016"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            307..2808
                     /locus_tag="VVR39_000831"
     CDS             307..2808
                     /locus_tag="VVR39_000831"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU6030346.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            3002..3697
                     /locus_tag="VVR39_000832"
     CDS             3002..3697
                     /locus_tag="VVR39_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030347.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3709..4125
                     /locus_tag="VVR39_000833"
     CDS             3709..4125
                     /locus_tag="VVR39_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030348.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4752..4844)
                     /locus_tag="VVR39_000834"
     CDS             complement(4752..4844)
                     /locus_tag="VVR39_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU6030349.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5005..5976
                     /gene="ruvB"
                     /locus_tag="VVR39_000835"
     CDS             5005..5976
                     /gene="ruvB"
                     /locus_tag="VVR39_000835"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU6030350.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            5957..6529
                     /locus_tag="VVR39_000836"
     CDS             5957..6529
                     /locus_tag="VVR39_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU6030351.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6760..7518
                     /locus_tag="VVR39_000837"
     CDS             6760..7518
                     /locus_tag="VVR39_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU6030352.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7527..8330
                     /locus_tag="VVR39_000838"
     CDS             7527..8330
                     /locus_tag="VVR39_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU6030353.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8352..9611
                     /gene="rseP"
                     /locus_tag="VVR39_000839"
     CDS             8352..9611
                     /gene="rseP"
                     /locus_tag="VVR39_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU6030354.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9624..11477
                     /locus_tag="VVR39_000840"
     CDS             9624..11477
                     /locus_tag="VVR39_000840"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU6030355.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVIAEEEVIRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11576..12955
                     /gene="bglA"
                     /locus_tag="VVR39_000841"
     CDS             11576..12955
                     /gene="bglA"
                     /locus_tag="VVR39_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6030356.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13148..14956
                     /gene="glmS"
                     /locus_tag="VVR39_000842"
     CDS             13148..14956
                     /gene="glmS"
                     /locus_tag="VVR39_000842"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU6030357.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            15075..16124
                     /locus_tag="VVR39_000843"
     CDS             15075..16124
                     /locus_tag="VVR39_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU6030358.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16224..20066)
                     /gene="spuA"
                     /locus_tag="VVR39_000844"
     CDS             complement(16224..20066)
                     /gene="spuA"
                     /locus_tag="VVR39_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU6030359.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPAASPA
                     DSAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITDPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            20483..20896
                     /gene="rpsL"
                     /locus_tag="VVR39_000845"
     CDS             20483..20896
                     /gene="rpsL"
                     /locus_tag="VVR39_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU6030360.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            20916..21386
                     /gene="rpsG"
                     /locus_tag="VVR39_000846"
     CDS             20916..21386
                     /gene="rpsG"
                     /locus_tag="VVR39_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU6030361.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            21811..23892
                     /gene="fusA"
                     /locus_tag="VVR39_000847"
     CDS             21811..23892
                     /gene="fusA"
                     /locus_tag="VVR39_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU6030362.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            23996..28387
                     /locus_tag="VVR39_000848"
     CDS             23996..28387
                     /locus_tag="VVR39_000848"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU6030363.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEAIYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIVDLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28489..28752
                     /locus_tag="VVR39_000849"
     CDS             28489..28752
                     /locus_tag="VVR39_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU6030364.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28796..29023
                     /locus_tag="VVR39_000850"
     CDS             28796..29023
                     /locus_tag="VVR39_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin, RelE/StbE family"
                     /protein_id="HEU6030365.1"
                     /translation="MKRGLKAELLEEVLNFLVQEKEHPARYRDHSLTASKHFQGVREC
                     YTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29044..29196
                     /locus_tag="VVR39_000851"
     CDS             29044..29196
                     /locus_tag="VVR39_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030366.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            29218..30459
                     /locus_tag="VVR39_000852"
     CDS             29218..30459
                     /locus_tag="VVR39_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU6030367.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30469..30699
                     /locus_tag="VVR39_000853"
     CDS             30469..30699
                     /locus_tag="VVR39_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6030368.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            30720..30797
                     /locus_tag="VVR39_000854"
                     /pseudo
     CDS             30720..30797
                     /locus_tag="VVR39_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            30967..31689
                     /locus_tag="VVR39_000855"
     CDS             30967..31689
                     /locus_tag="VVR39_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6030369.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            31906..33240
                     /gene="pepC"
                     /locus_tag="VVR39_000856"
     CDS             31906..33240
                     /gene="pepC"
                     /locus_tag="VVR39_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU6030370.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(33296..34207)
                     /locus_tag="VVR39_000857"
     CDS             complement(33296..34207)
                     /locus_tag="VVR39_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6030371.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(34231..35034)
                     /locus_tag="VVR39_000858"
     CDS             complement(34231..35034)
                     /locus_tag="VVR39_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU6030372.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(35062..36051)
                     /gene="manX"
                     /locus_tag="VVR39_000859"
     CDS             complement(35062..36051)
                     /gene="manX"
                     /locus_tag="VVR39_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU6030373.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT        10356 a         6995 c         8440 g        10358 t
ORIGIN      
        1 agattcagtc cactatacgt tcttcataaa tcaaaaagcg acataggttg tcggctattt
       61 attgtgaata cattaattag cattccagtt ttatcttcgg tctaaaataa gtattttgtg
      121 ctatacgaga taagcttctt gacttactcc ttgatttact gcataacaat gggataaaaa
      181 gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata cagtttttcc
      241 tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca aaattggaga
      301 gagaccatga gtttttacaa tcataaagaa attgagccta agtggcaggg ctactgggca
      361 gaacatcata catttaagac aggaacagat gcatcaaaac ctaagtttta tgcgcttgat
      421 atgttccctt atccgtctgg agctggtctg cacgtaggac acccagaagg ttatactgca
      481 accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca cccaatgggt
      541 tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg atactggtaa tgacccagca
      601 gaatttacag cggaaaacat tgccaacttc aaacgtcaaa tcaatgcgct tggattttct
      661 tatgactggg atcgtgaagt caacacaaca gatccaaact actacaagtg gactcaatgg
      721 attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc agtaaactgg
      781 gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg aacttctgaa
      841 cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa aatcacggct
      901 tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc tatcaaggat
      961 atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa agtaaaagga
     1021 acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg tgcgactttc
     1081 actgttttgg ctcctgaaca tgaattagta gatgccatca caagcacaga gcaagcagaa
     1141 gcagtagcag actacaaaca ccaagccagc cttaagtcag acttggctcg taccgacctt
     1201 gccaaagaaa aaactggtgt atggactggt gcttatgcca tcaatcctgt caatggtaag
     1261 gaaattccaa tctggattgc ggattacgtt cttgctagct atggtacagg tgcggttatg
     1321 gctgtgcctg cccacgatca acgtgactgg gaatttgcca aacaatttga ccttccaatc
     1381 gtcgaagtac ttgaaggtgg aaatgttgaa gaagctgcct acacagaaga tggccttcac
     1441 gttaattcag acttcctaga tggactcaac aaagaagacg ctattgccaa gattgtggct
     1501 tgcttggaag aaaaaggctg tggacaagag aaggtaacct accgtctccg cgactggctc
     1561 tttagccgtc aacgttactg gggtgagcca atcccaatca ttcattggga agatggaact
     1621 tcaacagctg tccctgaaag tgaattgcca cttgtcttgc ctgtaaccaa ggatatccgt
     1681 ccctcaggta ctggtgaaag tccactagct aacttgacag actggcttga agtgactcgt
     1741 gaagatggtg tcaaaggtcg tcgtgaaaca aatactatgc cacaatgggc aggttcaagc
     1801 tggtactacc tccgctatat tgacccacac aatactgaga aattggctga cgaggatctg
     1861 ctcaaacaat ggttgccagt agatatctac gtgggtggtg cggaacatgc tgtacttcac
     1921 ttgctttacg ctcgtttctg gcataaattc ctctatgacc tcggtgttgt tccaactaag
     1981 gaaccattcc aaaaactctt taaccaagga atgattttgg gaacaagcta tcgtgaccac
     2041 cgtggggctc ttgtggcgac tgacaaggtt gaaaaacgtg atggttcttt cttccatgtg
     2101 gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct caagaacgtt
     2161 gtcaacccag acgatgtggt ggaacaatac ggtgctgata cccttcgtgt ctatgaaatg
     2221 ttcatgggac cactcgatgc ttcgattgct tggtcagaag aaggtctgga aggaagtcgt
     2281 aagttccttg accgtgttta ccgtttgatt agaagtaagg aaattgttgc ggaaaacaat
     2341 ggcgctcttg acaaggttta caacgaaact gttaaagctg tcacagagca aattgattcc
     2401 ctcaaattca acacagccat tgcccaactt atggtctttg tcaatgcggc taacaaggaa
     2461 gacaagctct atgttgacta tgccaaagga tttatccaat tgattgcccc atttgcacct
     2521 cacttggcag aagaactctg gcaaactgtt gctgcaacag gtgagtcaat ctcttacgtg
     2581 acttggccaa catgggacga aagtaaactg gttgaagacg aaatcgaaat cgttgtccaa
     2641 atcaaaggta aagtccgtgc caaactcatg gtcgctaaag acctatcacg tgaagaattg
     2701 caagaaattg ctctagcgga tgaaaaagtc aaagcagaaa ttgacggtaa ggaaatcgtg
     2761 aaagtgatta gtgtaccaaa taaattggtt aatattgttg taaaataacc aatttatttg
     2821 ctgatttcca acctcaaaca gtttcccaaa ctgtttgagc caactaaact cgttaatatc
     2881 gttgtgaaat aaggtaggaa tccttcagag tagaatctgg aggatttttt gaatcttctt
     2941 atgaaagtat ggtatactat gggcaactat aaagtttgaa aagtgaaaaa aggagaaagc
     3001 tatgccagta aatgaatatg gtcaaatgat tggggagtca atggaaggtt atacaccagg
     3061 tgaactgcct tctattgatt tcttagaagg gcgttatgct aggatagagg ctctttcagt
     3121 ggaaaagcat gcggaggatt tgctagctgt ttatgggcct gatacgcctc aggagatgtg
     3181 gacctacctt tttcaggagc cagtagcaga tatgggggag ctggttagcc ttttacatca
     3241 gatgttggct cgtaaggacc gtttttacta tgcaatcata gacaaggcga ctggtaaggc
     3301 tttgggatct ttttctctca tgcgcattga ccagaataac cgagtaatag aagtcggagc
     3361 agtcactttt tctccagagc taaggggtac acggatagga actgaagctc agtatctcct
     3421 agctcgctat gtttttgagg agctaaacta tcgtcgctac gagtggaaat gcgatgcctt
     3481 aaatctgcca tccagacgag ctgcggagcg tttgagcttt atttatgaag gaaccttccg
     3541 tcaggcagtg gtttataagg gacgtacgag agatacggat tggttgtcta tgattgataa
     3601 ggactggcct caagtcaaag atcgtttgga aacatggttg cgtcctgaaa attttgataa
     3661 aaatggacag cagtacaaga gcttgagaga actttaagag gtgttgacat gattactatt
     3721 aaaaagcaag aaattgtcaa gctagaggat gttttacatc tctatcaggc tgtcggttgg
     3781 acaaattata cccatcaacc agagatgctg gagcaggcct tatctcattc attagtaatt
     3841 tatctggcac ttgatggtga tgctgtggtg ggcttgattc gtttggttgg agatggattc
     3901 tcatcagtat tggttcagga tttaatcgtt ttaccaatct atcagcgtca aggaattggt
     3961 agtgccttga tgaaagaggc tttagaggat tacaaagatg cctatcaagt ccagctggtg
     4021 acagaagaga cagaaagaac cttgggcttc tatcgttcta tgggctttga aatcttatcc
     4081 acctataatt gtatagggat gacttggatg aatcgtaaaa aataacaaaa cttgtttttt
     4141 cttaagcaaa atttaaggat ggtctagtat tatatagtca ttaaataaag acctcctaac
     4201 tttatttaat aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa
     4261 tcaggtggag ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt
     4321 cgatattttt cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga
     4381 atataactaa gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa
     4441 gtgactgtta attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg
     4501 cgtattaaat gagaagtgac atgtaagatt gtcgcttcgt ttacgaaatc aaaatttcta
     4561 tgaaattgat agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg
     4621 aagaaaatgt aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt
     4681 actagttcta tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt
     4741 cttttttgac actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg
     4801 accacaattg gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc
     4861 tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca cataagtgct aaacttagga
     4921 gtcacccaat caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg
     4981 agtagaattt tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt
     5041 cctcagtatt tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt
     5101 attgaagctg ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca
     5161 ggtctcggga aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag
     5221 cagacgtcgg gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta
     5281 gagcctgggg atgtcctttt tattgatgag atccatcgtt tgccaatgtc agtggaagag
     5341 gtgctttata gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt
     5401 agtcgtagtg ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct
     5461 ggtatgctct ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat
     5521 gcccatgctg acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc
     5581 actcatgagg cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat
     5641 cgtctcctca agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat
     5701 attattaccg ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg
     5761 gatcaaaaaa tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga
     5821 actctttctg tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac
     5881 ttgattcaaa aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca
     5941 tatgagcact taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag
     6001 agaaaatcca gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc
     6061 gtggttggca gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc
     6121 ttttgatcat gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga
     6181 aaccttatta ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa
     6241 aaatcaggtc tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga
     6301 tgctatgagt aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc
     6361 agattttgaa ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc
     6421 aactcctcat ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa
     6481 gaaaaattgg caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa
     6541 gctagggagt gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact
     6601 ttttcataat aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga
     6661 aaaatgggct tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg
     6721 gtataataaa acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa
     6781 gataaggctg tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg
     6841 gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg
     6901 ggcatggaag cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt
     6961 acggtctatg ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc
     7021 atgaacttgc cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt
     7081 aagattcaaa tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc
     7141 aaggctgagg aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat
     7201 ggtggacgtg ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc
     7261 aaaatcaatc caggtgacat cacagaggaa ttgattggca actatctctt tacccagcat
     7321 ttgcctaagg acttacgaga cccagacttg attatccgta ctagtggaga attgcgtttg
     7381 agcaatttcc ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg
     7441 cctgattttg acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc
     7501 cgatttggag gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg
     7561 cagggattgc cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga
     7621 tagcaatcgg aatcatagct atgctagcca tgcatgaact tttgaagatg agaggtctag
     7681 agaccatgac gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct
     7741 tggagaatta cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga
     7801 tttcaatcat gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt
     7861 tccctcttgc tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg
     7921 ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg
     7981 cctatcttgt tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata
     8041 aaacccttga gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta
     8101 tgatagttga cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta
     8161 ttttctttag cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt
     8221 ttggtgttaa ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg
     8281 atagtatgtt gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg
     8341 gaggaaacgc tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg
     8401 tgcacgagtt cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg
     8461 ccatcggtat gggacctaaa atttttgctc acattggcaa ggatggaacg gcctatacca
     8521 ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg
     8581 aaatcaagac aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca
     8641 tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg
     8701 attttgaaga caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag
     8761 tggatcacga tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag
     8821 atgttcaata tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggcccta
     8881 tgaacaattt tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg
     8941 tcagagatgt tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag
     9001 gagtaccaga aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa
     9061 gcttgatcca agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga
     9121 ctatttctga aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc
     9181 gttaccttct aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg
     9241 gttttacaac tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt
     9301 tccaaccgga tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagcgatg
     9361 ctgctaaaaa tggaattgaa aatatcttgt acttcttggc aatgatttcc attaatattg
     9421 ggatttttaa tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc
     9481 tagaagccat ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg
     9541 gagtggtcat catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct
     9601 tttttagata atcgaggaat attatgaaac aaagtaaaat gcctatccca acgcttcgcg
     9661 aaatgccaag cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc
     9721 gccaagtttc agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag
     9781 ctaaaaacat catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctccag
     9841 cccttcttag tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc
     9901 tttacaaact aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa
     9961 cctttacagc tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt
    10021 atcaaattca gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac
    10081 gtgagtttat catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg
    10141 tttatgatga gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca
    10201 aggctattat tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca
    10261 ttacatctgc tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat
    10321 ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag
    10381 tctctggtga agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa
    10441 tggcaacaaa cgagtacaaa ccaagcaacc gtgttatcgc tgaagaagaa gttattcgtg
    10501 ttgcaacgcc agatgttaaa tcaattgatg aagttgcagc cttcctcaat gttccagaag
    10561 aacaaacgat taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag
    10621 ttggaaatga ccaactcaac gaagtcaagt tgaaaaatca cttgggagca gatttctttg
    10681 acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac
    10741 cagttggttt gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca
    10801 atgcagttgt cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg
    10861 attttactgc agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg
    10921 gacaaggtgt ccttaacttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa
    10981 ctcgctattc agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa
    11041 tcatcatggg atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac
    11101 atgctcgcct ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca
    11161 atttccctaa agaattggca ccatttgatg tgcatttgat tactgttaat gtcaaggatg
    11221 aagaagcgca agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag
    11281 tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg
    11341 gtcttccaat ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga
    11401 tcaaggcaac tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa
    11461 tcctaagcaa gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt
    11521 tttaccttgt tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct
    11581 aagatttcca aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg
    11641 tgtagctggt gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa
    11701 tcgttactat aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg
    11761 ggatattgag cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc
    11821 acggattttt ccacaaggct gtggaaaagt caacactcaa ggtgtggatt tttatcgtaa
    11881 ggtctttgag gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga
    11941 tttacctttt gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc
    12001 ctatgaagac tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat
    12061 tacctttaac gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc
    12121 acataaggtg gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag
    12181 ccgggctgtt aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa
    12241 cttgacaccg gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc
    12301 ggcccttttt caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga
    12361 gttggtagaa atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga
    12421 actcattcgt gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt
    12481 tatggctcct cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga
    12541 gccttatgtg atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca
    12601 agggatttat gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt
    12661 gactgagaat ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca
    12721 agatgattac cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga
    12781 agatggtgcc aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct
    12841 caacagctat aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg
    12901 tctgaagaaa tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg
    12961 actctgactg attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac
    13021 tataccaatt tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc
    13081 tataaaagat gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt
    13141 atatactatg tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat
    13201 tcaagggctt gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga
    13261 tggtgctgat aaccatttgg tgaaggcggt tggtcgtatt gcagaactgt ctgccaagac
    13321 agctggtgtt gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc
    13381 aactgaggac aatgctcacc cacaccgctc tgagacagaa cgttttgtct tggtgcataa
    13441 tggggtgatt gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa
    13501 ggggcagaca gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg
    13561 gctctcagtt cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt
    13621 tgccttggtt gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact
    13681 tttgattggt cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg
    13741 tgaaactaac caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag
    13801 tgtggaagtt caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact
    13861 tgacttgtca gatatcggta agggaactta cccttactac atgctcaagg aaattgacga
    13921 gcaaccaact gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt
    13981 cgtagaccca gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc
    14041 tggaacatct taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac
    14101 accagttgaa cttggcatct catctgagtg gggctacggt atgccacttc tcagcaagaa
    14161 accactcttc atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt
    14221 caaggctaat gaaatgggaa ttccaagctt aacagtgaca aatgttccag gctcaaccct
    14281 ctcacgtgaa gccaactata ccatgctcct tcacgctggg cctgaaattg ccgtggcatc
    14341 aactaaagcc tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga
    14401 agcaaatggt aatgctaaag cgcaagcctt tgacctgatt catgaattgt caatcgtagc
    14461 tcagtctatc gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact
    14521 tcttgaaaca actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat
    14581 ggaagcaagt ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg
    14641 agaactcaag cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt
    14701 gtcagatcca gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg
    14761 tgccaaagtc ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct
    14821 tacgaccgta catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc
    14881 ttactttgca accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc
    14941 agtaacggta gaataagcta aaaaagtcta gttatctagg ctttttcttg tgagcaaatt
    15001 ggttgcttgt actcaagatt cgtgttagaa taatttttca aattgaagga cagagataga
    15061 caaggagaat cacaatggta gaattgggaa tttcaacatt tggggaaata acggagcttg
    15121 aagggactgg acaaacttac agtcatgctg aacgcattcg ccagttggtg gcagagattg
    15181 agctggctga caaggttggt ttggacgtat atgggattgg cgagcaccat cgggcggatt
    15241 ttgcagtatc agccccagag attgtcctgg ccgctggggc agtcaatacc aagaaaatcc
    15301 gtttgaccag tgcagtcagc attctgtcaa gcatggaccc gattcgtttg ttccaacagt
    15361 atgccactat cgatgctttg tcaaatggac gagcggagat tatggctgga aggggatctt
    15421 tcacggaatc tttccctctg tttggttatg acttgaaaga ctacgactct ctttttgatg
    15481 agaaattaga cttgcttcag ttagtcaatg aaaagaccaa gttagactgg caaggtcgat
    15541 tgactcaaac gattgctggt aaagaagttt atcctcgtcc agttcaggac aaattgccct
    15601 tgtggatagc tacaggtggt catgtcgaat caacagtgaa gattgctcag gctggtctac
    15661 cgattgtata tgctattatt ggtggtaatc cacgttattt taaaaagttg attcaggctt
    15721 atcgtgagat tggaagcgaa gcgggccatg ctgacaaaga cttgaaagtg ggagcccatt
    15781 cttgggggtg gattgcggaa gatggtgagc aggcggtgaa agattatttc catccgacta
    15841 agcaagtggt ggatgctatt tccaaagacc gtccgcactg gcaggaattg cgttatgagc
    15901 aatatttgga gcaggtaggg tcaaatggcg ccatgtttgt tggcaatcca gatcaggtgg
    15961 ccgaaaaatt gattcgcatg atagaggatt taggattgga ccgcttcatg cttcatctac
    16021 cgcttggttc tatgcctcat gaccaggttc tgagagctat tgaactcttc ggaacacaag
    16081 ttgcacccaa agtacgagct tattttgcta tgaaagaggc ttaataaaaa atcctaatca
    16141 agtttattag gacaacaaat attgtacgaa aattaatccc ccgagctata atgcttgggg
    16201 gatttttcta taggagggct agcttagttc tcttttttat tttttagtaa gaaaccgaga
    16261 ccaaggagcg caaggaggct gattcctgca aataggagtt tgttttcgtt tttgattcct
    16321 gtatttggaa gttcagcttg tctatctggg gttgcagata tattttcctt gctagagttt
    16381 tctaccgatt cttttcgaac cgcttctttt acagatgatg cttgtgcttc ttgtgctggt
    16441 tgttcagctt gtgaatcagc tgtagcttgg ctaggtttat tttccgcatc agctactttg
    16501 gcatctggtt tagtagaatc aggtctagct tctggagctg ggtcttgatg tgcagggtga
    16561 gaagcttcat tttgatgttc aggcttggaa ggggttgagt ctggtttctc ttctgcagtt
    16621 gactcatggc tagttccatt ttgagagact cgaagaacag tagctgtaag ggcattcaat
    16681 ttcaagcctt tttcagtcca ttcaagtcct ttcgggttgg caattccgac tgatcctgct
    16741 tggttttcat ctgccaaaac ttccgcattt cttagatgtg caaaggcagt tcccaaatta
    16801 aattcgcgag ctttttcatc cgcattgaca aagactgcgt agatatcgcc gtttggatca
    16861 gtgatttgat agccaatcac tacatcctct ttttccacac cattttggcc tgggacagtg
    16921 atgaggtgga cacggtcttt gatatcttga agactcttaa gtcggaaggc atctgtagat
    16981 tgacgaaggg caatcaaacc tttcatatag tcacggctct tgacattttc aggataagct
    17041 ttaccatctg tagccttagt ccagtcaaac ttgttgactg catcactaga atcgtaagag
    17101 tcatggatga agtaaggata gtcaaatggg ttgccgtcct tatcacgcaa caagtgagat
    17161 ttgtttggaa ccttatcctc tgctactgga gtcttgtagg ctgggtcacg gaattgttta
    17221 gtacgtccat attcctgacc ggagtggata aatggagttc cttgagctgt caagaccatg
    17281 agatttccaa gtcgtaaacg acggtggatt tcagcatagt tctcagcctt gcttgggtct
    17341 tttttgatag actgggcaat gatgtcaaag agggtcaagt tatcatgggc tgcgatgtat
    17401 tggatgacat ctccagggct gtcagcttca aagttagttg gttgagcaat gagattttta
    17461 aagatggtgt tgacatcacg cttgccacct gtgataaagg caggttgacc ttcgtttgga
    17521 taaccagatt tgaggttgtt acggatgtca tctgaaaaga cagcgacagt atcggtatgt
    17581 ttcatccaat cttggtcagc agctttagta ggcatgtttt catcaccggc ataggttctc
    17641 caaccttcgc ctaacatgat tagatttgga ttgagggcgc gtgcagcctt gtaagcttct
    17701 tcgatagaag cggcgtcatg gtctcccatc atatcgaagc ggaagccatc cactttgtag
    17761 gtatcaacta ggtatttgat agagtcaact aggagccgtt tggtcatatg gtgggttgtc
    17821 cccaagcgtc caccaccaaa gctagttcga ggtgtgccat cggcatccat aaagtggtag
    17881 tagtttggct ctaggtcttc aaagatatcg actttggctg tgtggttata aacgacatct
    17941 aggatagctc ccataccacg tttgtggatt tcgttgatga ggtttttaaa ttctgcgatt
    18001 cgtttttctg gattcttagg atcgcttgag tacataccag tcaaggagaa gtagttttga
    18061 gggtcatatc cccagttgta gttgctgttg cttgaagcat agtcagacaa gcgttcatgg
    18121 tttttcaatt cattgacaaa gtagtaagac aagactggaa ggagctggat atgggttaca
    18181 cccaagtctt tgagatagtc tagtttttca atgaaggctt caaaagtccc aaatggtttg
    18241 gtcaagtctt ttgcaatggc aggatctgaa gtgaagtcac gcacatgagc ttcgtagata
    18301 acggcgtctt cacgagtctt gaaattgtga atcttaccat aagtcaagtc ttgaggtccg
    18361 agtttagctg gatctacaaa ggcggcttta gccactttat gggcatcgtc aatcttggca
    18421 tcgtcgctat tccaagcagc aagagattta gcgtaaggat cgagtgcaag aacagtttta
    18481 ccttgacgct cgatttggta ttgataatag tagccagtga aatctgtgat tccgagtttg
    18541 tttgtgctgt ctagagtttg tttccaagtt cctctttccc ctttttcgag agcgacagtt
    18601 ccaactactt tgtcagggtc attcttgtcg tagacaacaa cagaaacctt atcagcactt
    18661 ggtgaccaaa gggtcaaatc aacttgtttt ccttcttctt ttaggtcagc tcccagtttg
    18721 ccatcatagc tgtatgtctc atctttcagg cgccagcttg ttttggtagt gaattggtcg
    18781 gaattgtagc taacagtata aggatgtttt gtgtcagaga aatctccgct gtaggtcact
    18841 ttcttaccag cttcatcgat tgcaacatcg gtaatagtta ccttgtttcc taggtgatta
    18901 gtgatgttgg agtgtttgag gatatcttct tttttagcac cgacaagtgt tgaaaagcta
    18961 ctttcaatgc tagaagtgcc tacgtgttgg gctcctgtca tacggatatc atggacatag
    19021 tatggatttg tgtaaatcga ttcatcatcg tcttttagga aaatttggct atgatttttc
    19081 aaatctgtga acttataatt ttctttacgg attttcacgt cgtctccttg tttgctctca
    19141 tctagtaata aaaatccaaa ttctcttgcg gcttcattaa gaggaatgtc gatatagcgg
    19201 ccatatttgc ctgtagccgt aaagtctgtt ccgtcaggcc attgagcgct acttggattt
    19261 tttacatctc cccagtacca gagagatttc ttgtcatagt tgccatctgt gcggtagtag
    19321 ttgacgcgaa cagttcctgc aggctgtggc tcgtaagaga aaaccttgta atcttggtct
    19381 aaccaagctt cgttcatttt tggaactagt ttttctacag atttatcgcc ggttagattt
    19441 tttccagctg tattgttgat gaggaagcta attttcttgg cttgttctcc ctttaatttg
    19501 acatctaggt aatagccgta gtcatctttc ttggcatcct tgaaggacaa agctccgttt
    19561 ggccagtttt cagatggttt ttcaacatcg tcccaagtcc atagtccttg agcatccttg
    19621 ttttcttcag gaagtttttt gacatggata cggaagtagt tatcttcgat gggctcttct
    19681 gccttagttt cagttgttac tggactagta gaagtagttg gctcacttga acgatcttgt
    19741 ccagtttgtg gtgctgaatc ggctgggctt gcagcaggtt tttcttctgt tttctctagg
    19801 gaagcgtttg catttctagg tgaagaaata tcactttcgt tcttaccaga gccagctgct
    19861 gtatcagtaa gaggttgggc aagggtggtt gtatttctgt tgttgggttc gttagtggtt
    19921 ggtgtacttt cgtcggatga gatagttggt gtagccatgg caagcaagac aaggcttgcg
    19981 ccgataagga cagaaccagt tccatttttg agggaacgga tgctgtagac catttttttc
    20041 tcagtgtgag atggtgtttt tctcataatg attctccaat caataaattt ctatatcagt
    20101 atagcatgta gtaaaacaat atgcaagcgt tttctttgat ttgtgaaaaa aattcctact
    20161 tttgagaagt tttctgtact attttatata tcagtataaa tgacggagat aaaaatgtca
    20221 cataagccaa gccgtattat taggaagatg atgtgttccc agctattttt attcagaaat
    20281 tgatctctaa cattaccaat aaaaaagaaa aatatcttga caagcaaggg aaaattttgt
    20341 tacaataata gacggtactt tttacttttg gtctctcaag agtgtacagg gacgtgctga
    20401 caaatgttgc aaaagtacac acagatgata tctgtcacca agtgtatcat caccaaaaat
    20461 aaaaaaacac aggagaatgt agatgcctac aattaaccaa ttggttcgca aaccgcgtaa
    20521 atcaaaagta gaaaaatcta aatcaccagc tttgaacgtt ggttacaata gtcataaaaa
    20581 agttcaaaca aacgtttctt caccacaaaa acgtggtgtt gcaactcgtg ttggaacaat
    20641 gacacctaaa aaacctaact cagcccttcg taaattcgct cgtgtacgtt tgagcaacct
    20701 tatcgaagtt actgcctaca tcccaggtat cggacacaac ttgcaagagc acagcgtggt
    20761 gcttcttcgc ggtggacgtg taaaagacct tccaggggta cgttaccata tcgtccgtgg
    20821 tgcacttgat actgcaggtg ttaacgatcg taaacaaggc cgttctaaat acggtactaa
    20881 acgtccaaaa gcataaggaa aggggataaa gagaaatgag tcgtaaaaat agagctccaa
    20941 aacgtgacgt attgccagat ccgctataca attcacaact agttactcgt cttatcaacc
    21001 gcgttatgct tgatggtaaa cgtggtactg ctgcttcaat cgtttacggt gcttttgagc
    21061 aaatcaaaga agctactggc aacgatgcac ttgaagtatt tgaaacagct atggaaaaca
    21121 tcatgcctgt acttgaagta cgtgcacgtc gtgttggtgg ttctaactac caagtcccag
    21181 ttgaagttcg tccagaacgt cgtacaacac ttggacttcg ttggttggta acaatcgctc
    21241 gtcttcgtgg tgaacacaca atgcaagacc gtcttgcaaa agaaatcttg gatgctgcta
    21301 acaacactgg tgcagcagtt aagaaacgtg aagatactca ccgtatggct gaagctaacc
    21361 gtgcattcgc acacttccgt tggtaagata ggatgcgaaa gcgttaagaa agtcccagag
    21421 aaaataggga atcgaagcag gttgcggttg caaccaatga gattcatctt tttctccaga
    21481 cttttagctt gagctcaact aaatcatgat gctaggcacg gtaaggatgc aaggtgaaaa
    21541 taggaaactg acgcagtatt caacgaatac aaggagtttt atctttttca cgcaacatcc
    21601 cgttccagct cacatcggct aactaacttt agcctgggtt caaattagct aaatcgatta
    21661 gtattagcta taactcagct taccatctcg taagttgaaa ccaacaatag catgaaaaca
    21721 ttgagaacgg gtaggtcctg cctatccgtt tttattaaaa tcgtgttata atagaataga
    21781 aatcaaaaat aaataggaga aacaaacctc atggcacgcg aattttcact tgaaaaaact
    21841 cgtaatatcg gtatcatggc tcacgtcgat gccggtaaaa caacaactac tgagcgtatt
    21901 ctttactaca ctggtaaaat ccacaaaatc ggtgaaactc acgaaggtgc gtcacaaatg
    21961 gactggatgg agcaagagca agaacgtggt atcacgatca catctgctgc gacaacagct
    22021 caatggaaca accaccgcgt aaacatcatc gacacaccag gacacgtgga cttcacaatc
    22081 gaagtacaac gttctcttcg tgtattggat ggtgcggtta ccgttcttga ctcacaatca
    22141 ggtgttgaac ctcaaactga aacagtttgg cgtcaagcaa ctgagtacgg agttccacgt
    22201 atcgtatttg ccaacaaaat ggacaaaatc ggtgctgact tcctttactc tgtaagcaca
    22261 cttcacgatc gtcttcaagc aaatgcacac ccaatccaat tgccaatcgg ttctgaagat
    22321 gacttccgtg gtatcattga cttgatcaag atgaaagctg aaatctatac taacgacctt
    22381 ggtacggata tccttgaaga agacatccca gctgaatacc ttgaccaagc tcaagaatac
    22441 cgtgaaaaat tgattgaagc agttgctgaa actgacgaag aattgatgat gaaatacctc
    22501 gaaggtgaag aaatcactaa cgaagaattg aaagctggta tccgtaaagc gactatcaac
    22561 gttgaattct tcccagtatt gtgtggttca gccttcaaaa acaaaggtgt tcaattgatg
    22621 cttgatgcgg ttatcgacta ccttccaagt ccacttgaca tcccagcaat caaaggtatt
    22681 aacccagata cagacgctga agaaattcgt ccagcatctg acgaagagcc atttgcagct
    22741 cttgccttca agatcatgac tgacccattc gtaggtcgct tgacattctt ccgtgtttac
    22801 tcaggtgttc ttcaatcagg ttcatacgta ttgaatactt ctaaaggtaa acgtgaacgt
    22861 atcggacgta tccttcaaat gcacgctaac agccgtcaag aaatcgacac tgtttactca
    22921 ggtgatatcg ctgctgccgt tggtttgaaa gatactacaa ctggtgactc attgacagat
    22981 gaaaaagcta aaatcatcct tgagtcaatc aacgttccag aaccagttat ccaattgatg
    23041 gttgagccaa aatctaaagc tgaccaagac aagatgggta tcgcccttca aaaattggct
    23101 gaagaagatc caacattccg cgttgaaaca aacgttgaaa ctggtgaaac agttatctca
    23161 ggtatgggtg aacttcacct tgacgtcctt gttgatcgta tgcgtcgtga gttcaaagtt
    23221 gaagcgaacg taggtgctcc tcaagtatct taccgtgaaa cattccgcgc ttctacccaa
    23281 gcacgtggat tcttcaaacg tcagtctggt ggtaaaggtc aattcggtga tgtatggatt
    23341 gaatttactc caaacgaaga aggtaaagga ttcgaattcg aaaacgcaat cgtcggtggt
    23401 gtggttcctc gtgaatttat cccagcggtt gaaaaaggtt tggtagaatc tatggctaac
    23461 ggtgttcttg caggttaccc aatggttgac gttaaagcta agctttatga tggttcatat
    23521 cacgatgtcg actcatctga aactgccttc aagattgcgg cttcactttc ccttaaagaa
    23581 gctgctaaat cagcacaacc agctatcctt gaaccaatga tgcttgtaac aatcactgtt
    23641 ccagaagaaa accttggtga tgttatgggt cacgtaactg ctcgtcgtgg acgtgtagat
    23701 ggtatggaag cacacggtaa cagccaaatc gttcgtgctt acgttccact tgctgaaatg
    23761 ttcggttacg caacagttct tcgttctgca tctcaaggac gtggtacatt catgatggta
    23821 tttgaccact acgaagatgt acctaagtca gtacaagaag aaattattaa gaaaaataaa
    23881 ggtgaagact aatccgtcct cactctagaa ggaagtcact tagtggcttc cttttgtctt
    23941 tagaaaatac ctctaaatat ggtaaaatag tagaagaata atgtgaggaa aatgaatgtc
    24001 aaatagtttt gaaattttga tgaatcaatt ggggatgcct gctgaaatga gacaggctcc
    24061 tgctttagca caggccaata ttgagcgagt tgtggttcat aaaattagta aggtatggga
    24121 gtttcatttc gtattttcta atattttacc gattgaaatc tttttagaat taaagaaagg
    24181 tttgagcgaa gaattttcta agacaggcaa taaagctgtt tttgaaatta aggctcggtc
    24241 tcaagaattt tcaaatcagc tcttgcagtc ctactatagg gaggctttct ctgaaggtcc
    24301 atgtgctagt caaggtttta agtcccttta tcaaaatttg caagttcgtg ctgagggtaa
    24361 tcagctattt attgaaggat ctgaagcgat tgataaggaa cattttaaga agaatcatct
    24421 tcctaattta gccaaacaac ttgaaaagtt tggttttcca acttttaact gtcaagtcga
    24481 gaagaatgat gtcctgaccc aagagcagga agaggccttt catgctgaaa atgagcagat
    24541 tgttcaagct gccaatgagg aagcgctccg tgctatggaa caactggagc agatggcacc
    24601 tcctccagcg gaagagaaac cagtctttga ttttcaagcg aaaaaagctg cagctaaacc
    24661 caagctggat aaggcggaga ttactcctat gatcgaagtg acgacagagg aaaatcgtct
    24721 ggtatttgaa ggggttgttt ttgatgtgga gcaaaaagtg actagaacag gtcgtgtttt
    24781 aatcaacttt aaaatgacgg actatacttc aagtttttct atgcaaaagt gggttaaaaa
    24841 cgaggaagag gcccagaagt ttgacctcat caagaagaat tcttggctcc gagttcgagg
    24901 gaatgtggag atgaataact tcacacgcga tttgactatg aacgtacagg atctgcagga
    24961 agttgttcac tatgagcgga aggatttgat gccagaaggt gagcgtcggg ttgagtttca
    25021 tgctcatact aacatgtcga ctatggatgc tttgccagag gtcgaagaga ttgttgcaac
    25081 agctgctaag tggggacaca aggcggttgc tatcacagac catgggaatg tccagtcctt
    25141 tccacatggc tataaggcgg ctaagaaagc gggaatccag ctgatctatg ggatggaagc
    25201 caatatcgtg gaggaccgtg tccctatcgt ctataacgaa gtggagatgg acttatcaga
    25261 agcaatctac gtggtctttg acgtggaaac gacgggactt tcagctatct ataatgactt
    25321 gattcaggtt gcggcctcta agatgtacaa ggggaatgtt attgctgaat ttgatgaatt
    25381 tatcaatcct gggcatccct tgtcagcttt tactacagag ttaactggaa ttacagatga
    25441 tcatgtcaaa aatgccaaac cactagaaca agttttgcaa gaattccaag aattttgcaa
    25501 ggatacggtc ctagttgccc acaatgctac ctttgacgtt ggctttatga atgctaatta
    25561 tgagcggcat gatcttccaa agattagtca gccagttatt gatacgctgg agtttgctag
    25621 aaacctctat cctgagtata aacgccatgg tttggggcct ttgaccaagc gttttggtgt
    25681 ggccttggaa catcaccaca tggccaacta cgatgcggaa gcgactggtc gtctgctttt
    25741 catctttatc aaagaggtag cagaaaaaca tggtgtgacc gatttagcta gactcaacat
    25801 tgatctaatc agtccagatt cttacaaaaa agctcggatc aagcatgcga ccatctatgt
    25861 caagaatcag gtaggtctaa aaaatatctt taagctggtt tccttgtcta ataccaagta
    25921 ttttgaagga gtgccacgga ttccgagaac ggttctagat gcccatcgag agggcttgat
    25981 tttaggttca gcctgttcag agggtgaagt ttttgacgtg gtcgtttctc aaggtgtgga
    26041 tgcggcggtt gaggtggcca agtattatga ctttatcgag gtcatgccac cggctatcta
    26101 tgcgcccttg attgccaaag agcaggtcaa ggatatggag gaactccaga ccattatcaa
    26161 gagtttgata gaggttggag accgccttgg caagcctgtt ttggctacgg gaaatgttca
    26221 ctatatcgaa ccggaagaag agatttatcg tgaaattatc gtccgtagtt tgggacaggg
    26281 tgcgatgatt aaccgaacta tcggtcatgg tgaacatgcc caaccagcac cacttccaaa
    26341 ggctcatttt cgaacgacta atgagatgtt ggatgaattt gcctttttgg gagaggaact
    26401 ggctcgtaaa ctggttattg aaaacaccaa tgccttggca gaaatatttg aacccgttga
    26461 agtcgttaag ggtgacttgt atacgccttt catcgacaag gctgaagaaa cagttgctga
    26521 gttgacctat aagaaagctt ttgagattta tggaaatccg ctgccagata ttgttgattt
    26581 gcggattgaa aaagaattaa catccatact ggggaatgga tttgctgtga tttatctggc
    26641 atcgcagatg ctggtgcaac gttctaatga acggggttat ttggttggtt ctcgtgggtc
    26701 tgtcggatct agtttcgttg cgaccatgat tgggattacg gaggtcaatc ctctctctcc
    26761 tcactatgtc tgtggtcagt gtcagtacag tgagtttatc acagatggtt cgtacggttc
    26821 aggatttgat atgccccata aggactgtcc aaactgtggt cacaaactca gtaaaaacgg
    26881 acaggatatt ccgtttgaga ccttccttgg ttttgatggg gataaggttc ctgatattga
    26941 cttgaacttc tcgggagaag atcagcctag cgcccacttg gatgtgcgtg atatctttgg
    27001 tgaagaatat gccttccgtg cgggaacagt tggtacggta gctgccaaga ctgcctatgg
    27061 atttgtcaaa ggttacgagc gagattatgg caagttttat cgtgatgcag aagtagaacg
    27121 cctcgctcaa ggagcggcgg gtgtcaagcg gacaacaggc caacacccgg ggggaatcgt
    27181 tgttattccg aactacatgg atgtctacga ttttacgcct gtccagtatc cagcagatga
    27241 tgtcacggct gaatggcaga ccactcactt taacttccac gatatcgatg agaacgtcct
    27301 caaactcgat gtactgggac atgatgatcc gactatgatt cgaaaacttc aggatttgtc
    27361 tggtattgac cctaataaaa ttcctatgga tgacgaaggc gtgatggcac tcttttctgg
    27421 gactgatgtg ctaggggtaa cacctgaaca aattggaacg cctacgggta tgttggggat
    27481 tccagagttt ggaacaaatt tcgtacgtgg aatggtagac gaaacccatc cgacaacctt
    27541 tgcggaattg cttcagctgt ctggtctgtc ccacggtact gatgtttggt tggggaatgc
    27601 tcaggatctg attaagcaag gaatagtgga cctatcgact gttatcggtt gtcgggacga
    27661 catcatggtt tacctcatgc atgcgggtct ggaacctaag atggccttta ccattatgga
    27721 acgggtacgt aagggtttgt ggctaaagat ttcagaagag gagagaaatg gctatatcga
    27781 agcaatgaag gctaataagg tgccagagtg gtatatcgaa tcctgtggga aaattaagta
    27841 catgttccct aaggcccatg cggcagccta cgttatgatg gccttgcgtg tagcttactt
    27901 caaggttcac catcctattt attactactg tgcttacttc tccattcgtg ctaaggcttt
    27961 tgatatcaag accatgggtg cgggcttgga ggtcatcaag cgcagaatgg aagaaatctc
    28021 tgaaaaacgg aagaacaatg aagcctctaa tgtggaaatc gatctctata caactcttga
    28081 gattgtcaat gagatgtggg aacgaggttt caagtttggt aaattagatc tctactgtag
    28141 tcaggcgaca gagttcctca tcgacgggga tacccttatc ccaccatttg tagcaatgga
    28201 tggtctggga gagaacgttg ccaagcaact ggtgcgggcg cgtgaagagg gagaattcct
    28261 ctctaaaaca gaactacgca agcgtggtgg actctcatca accttggttg aaaagatgga
    28321 tgagatgggt attcttggaa atatgccaga ggataaccag ttgagtttgt ttgatgagtt
    28381 gttttaaaaa attgcttaat aatctattaa aagaggctaa cgtatatcca atagatttac
    28441 attagctttc ttttttgtta aaatagtcta tggaaagagg gtgagagtat gtcaaagatg
    28501 agtataagca tccgtctgga tagtgaggtt aaggagcagg cccaacaggt gtttagtaat
    28561 ctgggaatgg atatgacaac agctattaat attttccttc gtcaggcaat tcaatatcag
    28621 ggattacctt ttgatgttag actagacgaa aatcggaagt tgctccaagc gttaacggat
    28681 ttagaccaaa atcgtaatat gagccagtct tttgaatcag tctcagattt gatggaggac
    28741 ttacgtgctt aagattcgtt atcataaaca gttttaaaaa gattttaagt tggctatgaa
    28801 gcgtggtttg aaggcagaat tattagaaga agttttgaat tttctggttc aagaaaaaga
    28861 acatcctgcc agatatcgtg atcattcatt gacggcatcc aagcattttc aaggagttcg
    28921 tgaatgctat acccagccag attggctttt ggtttataaa gtagacaagt cggaattgat
    28981 tttaaatttg ctgaggacag gcagtcacag tgatttattt taatctattt taagggggtt
    29041 ctcatgaaac taagaatatt tgcggaagat aagccggcta agaaggtatt tgaatatcaa
    29101 ttagaacttg ctgatcgtac aattcttcta tcgacagcac tcttgtcagg tgctattgct
    29161 ttagcaggaa tcttttctgc tttgaaagaa aaataaaaat agaaaagaga aaacaggatg
    29221 gttttaccaa attttaaaga aaatctagaa aaatatgcga aattgttggt tgcgaacgga
    29281 attaacgtgc aacctggtca cactttggct ctctctattg atgtggagca acgtgaattg
    29341 gcacatctaa tcgtgaaaga agcttatgcc ttgggtgcgc atgaggtcat cgttcagtgg
    29401 acagatgatg tgattaaccg tgagaaattc ctccatgccc cgatggagcg tttggacaat
    29461 gtgccagaat acaagattgc tgagatgaac tatctcttgg agaacaaggc tagccgtctt
    29521 ggagttcgtt catctgatcc aggtgccttg aacggagtgg acgctgacaa gctttcagct
    29581 tctgctaaag ctatgggact tgccatgaag ccaatgcgaa tcgcaactca atctaacaag
    29641 gttagctgga ctgtagcagc cgctgctgga cttgagtggg ctaagaaagt cttcccaaat
    29701 gctgcgagcg acgaagaagc agtcgatctc ctttgggacc aaatcttcaa aacttgccgt
    29761 gtctacgaag cagatcctgt taaggcctgg gaagagcatg cagccattct caagagcaag
    29821 gccgatatgc ttaataagga gcaattttca gcccttcact acacagcgcc aggaacagat
    29881 ttaacacttg gtttgccaaa gaaccacgtt tgggaatcag ctggtgctgt caatgcacag
    29941 ggcgaaggat tcttgccaaa tatgccgaca gaagaggtct tcacagcgcc tgacttccgt
    30001 cgtgcagatg gttatgtcac ttctacaaaa ccgcttagct acaacggaaa tatcattgaa
    30061 ggcattaagg tgacctttaa ggatggacaa atcgtagata tcactgctga gaagggtgat
    30121 caggttatga aagaccttgt ctttgaaaat gcgggtgcgc gtgccttggg tgaatgtgcc
    30181 ttggtaccag atccaagtcc aatttctcag tcaggcatta ccttctttaa cacccttttc
    30241 gatgaaaatg cgtcaaacca cttggctatc ggtgcagcct atgcgactag cgttgttgat
    30301 ggagcggaga tgagcgaaga ggagcttgaa gctgcagggc ttaaccgttc agatgttcac
    30361 gtagacttta tgattggttc taaccaaatg gatatcgatg gtattcgtga ggatggaacg
    30421 cgggtacctc ttttccgtaa tgggaattgg gcaaattaag gagataatat gttaggaagt
    30481 atgttcgttg gtctcctagt gggattttta gcaggtgcta tgaccaatcg tggagagcga
    30541 atgggatgtt ttggaaaaat gtttctcggt tggatcggag cctttctagg tcacttgctc
    30601 tttggaactt gggggccagt tttatcagga acagctatta tcccagcgat tttaggagcc
    30661 atgattgttt tagctatttt ttggagacga ggaagttaat ttcctaaatc tgatactcaa
    30721 tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctcaaagcac tgctttgagg
    30781 ttggagatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg
    30841 acgaagtcag taacatatat acggcaaggc gacgttgacg cggtttgaag agatttttga
    30901 agagtatgaa acgaaaagga ggttggtcat tgtactagcc tccttttgat atgatataat
    30961 agttctatga gattagataa atttttagtt gcctgtgcgg tgggaagtcg gactgaggtc
    31021 aaaaacttgc tcaaggctgg gcgcgtgact gtaaatggta aaaaagaaaa atcagctaaa
    31081 ttgcagattg atgaaaaaat agatgagatt cgctttgatg ggcaagtgtt ggagtatgaa
    31141 gagtttgtct actacatgat gaacaagccc aaaggagtta tctcagcgac tgaggatccc
    31201 aagcacagaa ccgttctgga cttgttggat gacttggcgc ggagtaagga agttttccca
    31261 gtaggacgct tggatattga cacgcatggt cttttgctct tgaccaatga tggtcagctg
    31321 gctcatgttc ttctttcgcc caagcgtcat gtggacaaga cttatctggc acaagtcaag
    31381 ggaatcatga cccaagaaga tgtggagaca tttgctgagg gtattcctct caaagacttt
    31441 acctgtcaac ccgctatact ggagcttgta tccatagata cagaaaagaa tcaaagccaa
    31501 atccgtgtga ccattgcaga agggaagttt catcagatca agcgtatggt gggctactgt
    31561 ggcaaggaag tggtggactt gcaacgattg actatgggaa ctttagtatt agatgagaac
    31621 ctagaacgag gggaatggcg tcgcttgacc aaggaagaat tagaaattct ccgcgctaat
    31681 attatttaat ttagtttaat actcaatgaa aatcaaagag caaactagga aactagccgc
    31741 aggctgtact tgagtacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    31801 ataaattcga aaaaggtgag ggacaatgtc ctcgcctttt atgtttttta gttgcttcct
    31861 ttgtgaaaag agttataata gactgtagaa taaaaggagg aatctatgaa cgcgattcaa
    31921 gaatcattta ctgataaact atttgccaac tatgaagcaa atgtaaaata ccaagcgatt
    31981 gaaaatgctg ccagccacaa cggaattttt gcagctctgg aacgtcgcca aagccatgta
    32041 gacaacacac ctgttttctc attggattta accaaggaca aggtcactaa ccagaaagcg
    32101 tctggtcgtt gctggatgtt tgcggctctc aacaccttcc gccacaaact catctcgcaa
    32161 tacaaattgg agaactttga attgtcacaa gcccacactt tcttctggga taagtatgag
    32221 aaatcaaact ggttcttgga gcaagtcatt gcgacttcag accaagaatt gactagccgc
    32281 aaggttagct tcttactcca aacacctcaa caagatggtg gtcaatggga tatggtcgtt
    32341 tccctctttg aaaaatacgg tgtcgtgcct aagtcagttt atcctgagtc tgtttcatct
    32401 agcagcagtc gtgagctaaa tgcgatcctt aataaattgc ttcgtcaaga tgctcaaatc
    32461 ttgcgtgact tgcttgtttc tggtgcagat caagcgactg ttcaagctaa gaaagaagac
    32521 ctcttgcaag aaatctttaa ctttcttgct atgtcattag gacttccacc acgcaagttt
    32581 gactttgctt atcgcgataa agataacaac tacaaaagtg aaaaaggaat cacaccacaa
    32641 gagttttaca agaaatatgt caatcttcct ttagaagact acgtttctgt tatcaatgct
    32701 ccaactgctg ataaacctta cggaaaatct tacacagttg agatgttggg gaatgtggtt
    32761 ggtagccgtg cagttcgcta catcaacgtt ccaatggagc gcttgaaaga attggcgatt
    32821 gcccaaatgc aagcaggtga gactgtttgg tttggttctg atgtcggcca gctcagcaac
    32881 cgtaaggctg gcatccttgc gacagatgtt tatgactttg aatcaagcat ggacattaaa
    32941 cttactcaag acaaggctgg acgtttggac tatagtgaaa gcttgatgac ccacgccatg
    33001 gtcttgacag gtgttgactt ggacgaaaat ggtaaatcaa ccaagtggaa ggttgaaaac
    33061 tcatggggag acaaggtcgg tacagatggt tactttgttg cctcagacgc ttggatggac
    33121 gaatacacat accaaatcgt tgttcgtaag gaattgctga cagcagaaga acaagctgcc
    33181 tatggagcag aaccaatcgt acttgcacca tgggatccaa tgggagcctt ggctgaataa
    33241 aagcatagaa aaaaggaatc agattttaga acctggttcc tttttagttg cttgattaca
    33301 tgatgtgaag aacatgtgcc acaataccca ctgcgaagag ggcaaggata atagtgattg
    33361 gagatacttt tttcttaagt aagtacatgc aaagtaaagt aaggagtagt cctgataatc
    33421 caggaatcaa catatccaag ttttgttgga aagtagtaac tttttcagga gtttgagaca
    33481 atccttgtcc tacttgtgcg aatgcttctt ggataccttt agacccttct ggcaatttat
    33541 cccaatggat ataagccttt tcatctagtt gaactttaga aacatcgaaa gcaaatttaa
    33601 tatttaccca gcgttgaaca aggacagcaa gaatgaacat cccaaggata gaagctcctt
    33661 tagtgatatc ttgaaggata ccaccagaca tatctttagt gatttctgat ccagccttgt
    33721 atccaatctc ttgaacatac cacaagaatg acatacgaat caagttccat gcaacaaaga
    33781 agaggagtgg ccccaagata ttgccagtaa gggcaagtga agcaccgaga gatccaagga
    33841 ttgggcgtac tgtaaaccag aatactgggt caccgatacc agcaagaggt cccatcatac
    33901 cgattttaac cccttggata gcagcgtcat cgatttccac accgttagca cgttcttctt
    33961 caagcgcaag agtaaccccc atgactggag cagctacgta tggatgagtg ttgaagaact
    34021 caaggtgacg ttcaagagca gcgatttgat cttctttttt agtatagagt tttttgatag
    34081 ctggaatgag tgtataagcc cagcccaagt tttgcatccg ttcaaagttc caagaccctt
    34141 gtaagaaggt tgaacgccac caaacttttt tacgatctga tttagttaat tgaagttttt
    34201 cagtcatgat gttttcagtc ctttcttatc ttagtagtct tctaggatat cgccgattgg
    34261 gtcgttagaa gttgcggctc ctccgccacc atttccacca gttttagaaa ggtgaaggta
    34321 gataagagcg atagcaacac cgatagcacc gaatccgatt agagtaatat ctgacacagc
    34381 agcgagaacg aaaccaagag cgaagaatgg ccatacttca cgagttgcca tcatgttgat
    34441 aaccatggcg taaccaacgg caacgaccat accaccaccg atagccatac catctttgag
    34501 ccagtctggc atggcactaa ggatactttg tacagtttca gttggtacca taaggagaag
    34561 agctgcagga agcgcgatac gaagtccttg gaagagtagc gcaatgaaat gcgcacgctc
    34621 cacagcgccg aagtcacctt ttttagcggc agcatctgca gtatgaacca aaccaactga
    34681 aattgtacga acaatcattg tcaagaaaag tccagctacg gcaagaggga tagcaaccgc
    34741 ttgggcaaca ccgataccag tcttggtaaa gtcaccacca agaaccatga taatggcagc
    34801 agcgacagaa gcaagtgcag catcaggagc gatagcagca ccgatatttg accaaccaag
    34861 ggcaatcatt tgaagcgatc caccgaggat aatccctgct tccaagtgac ctgttacaag
    34921 cccaataagg gtacaggcta caagtggttg gtgaaattgg aactggtcga ggatgccttc
    34981 aagacctgca aagaaggcta caacgactac taaaaccata gaaataatag acatgtttaa
    35041 aatcctttca taaataatgg cttatttgac attggctttg ttaatcaagt caaacaaatc
    35101 ttttttagaa tcatttggta ctttacggac atcaaattca acacccaagt cacgcatttt
    35161 ttcaaatgta gcaacatctt ctttgtccat agacaaaacg gtattgacca atgttttacc
    35221 tgttgagtga gccatagaac caacgttaag agtcttgatt ggcacgccgc cttcgatggc
    35281 acgaagggca tcttgaggtg tttcaaacaa gataagggca tgtgtttctc caaaacgtgg
    35341 gtcttttgaa atctcaatca gtttttgaat tggaaccacg ttagccttga cattacctgg
    35401 agctgcttgt ttaatcaatt ctttacgaag gtcgtcttta gccacgttat ctgaagcaac
    35461 gatgatacga tttgcttttg aatctggagt ccaagcagtt gcaacctgac cgtgaagtag
    35521 acgtgtgtca agacgggcaa gattgatttt caatttaccg tctccgataa cagttccttc
    35581 tgggatagca gtttgggcaa ctggagcagc tgcagcgctt gcaacttctt caactggatt
    35641 tagctcttct ggaagagctt tgatgccatc tttggcttct ttaatgatat tagcagcgac
    35701 tttttctaca cctgcagcag cgtccatgag gcgctctgtg taggcttgaa tcaacatcgg
    35761 taagttaagt cctgtgatga tggcaaactt acgctcagga ttttctccca tcacgcgact
    35821 agcttggtta aatggagaac cactccaaag gtcagccaaa actagaacct catcttctgc
    35881 gtcaaatgca gcaacagcgt tattaaactt agcgtataga tcatcaggac cttcatttgg
    35941 cataaaggtc acaacttgaa ccttttcttg ttcaccaaag atcatagatc ctgactgatg
    36001 aatacccgca gcaaattcgc cgtggctcgc aataatgatt ccgatactca ttattgtcat
    36061 tcctcctttt ttgttttagt tttcatttaa gaaaacttta agactgttta agtataaacc
    36121 gttttcataa aaaaagcaac tatttatca
//
LOCUS       DAVHSL010000017        35826 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000017 DAVHSL010000000
VERSION     DAVHSL010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.017"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..242
                     /locus_tag="VVR39_000860"
     CDS             <1..242
                     /locus_tag="VVR39_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6030374.1"
                     /translation="LPTLTTPSVIIMDNARFHRMGKLELLCEEFGYKLLPLPPYSPEY
                     NPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            398..736
                     /locus_tag="VVR39_000861"
     CDS             398..736
                     /locus_tag="VVR39_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU6030375.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            926..2362
                     /locus_tag="VVR39_000862"
     CDS             926..2362
                     /locus_tag="VVR39_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6030376.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYKEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2414..2653
                     /locus_tag="VVR39_000863"
     CDS             2414..2653
                     /locus_tag="VVR39_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU6030377.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2783..3097
                     /locus_tag="VVR39_000864"
     CDS             2783..3097
                     /locus_tag="VVR39_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU6030378.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3215..5194
                     /locus_tag="VVR39_000865"
     CDS             3215..5194
                     /locus_tag="VVR39_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU6030379.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSLDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5204..5518
                     /locus_tag="VVR39_000866"
     CDS             5204..5518
                     /locus_tag="VVR39_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU6030380.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5549..6055
                     /locus_tag="VVR39_000867"
     CDS             5549..6055
                     /locus_tag="VVR39_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030381.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            6135..7481
                     /gene="celB"
                     /locus_tag="VVR39_000868"
     CDS             6135..7481
                     /gene="celB"
                     /locus_tag="VVR39_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU6030382.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITIAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7861..8037
                     /locus_tag="VVR39_000869"
     CDS             7861..8037
                     /locus_tag="VVR39_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030383.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8439..10652
                     /locus_tag="VVR39_000870"
     CDS             8439..10652
                     /locus_tag="VVR39_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU6030384.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFRKAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSDKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10874..11350)
                     /locus_tag="VVR39_000871"
     CDS             complement(10874..11350)
                     /locus_tag="VVR39_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU6030385.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11573..14776
                     /locus_tag="VVR39_000872"
     CDS             11573..14776
                     /locus_tag="VVR39_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU6030386.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQRWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKHGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15155..15540
                     /gene="tnpA"
                     /locus_tag="VVR39_000873"
                     /pseudo
     CDS             15155..15540
                     /gene="tnpA"
                     /locus_tag="VVR39_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15919..16548)
                     /locus_tag="VVR39_000874"
     CDS             complement(15919..16548)
                     /locus_tag="VVR39_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6030387.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16558..17559)
                     /locus_tag="VVR39_000875"
     CDS             complement(16558..17559)
                     /locus_tag="VVR39_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6030388.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17590..18231)
                     /locus_tag="VVR39_000876"
     CDS             complement(17590..18231)
                     /locus_tag="VVR39_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU6030389.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18250..19065)
                     /locus_tag="VVR39_000877"
     CDS             complement(18250..19065)
                     /locus_tag="VVR39_000877"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU6030390.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19336..19770
                     /locus_tag="VVR39_000878"
     CDS             19336..19770
                     /locus_tag="VVR39_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030391.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            19782..20972
                     /locus_tag="VVR39_000879"
     CDS             19782..20972
                     /locus_tag="VVR39_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU6030392.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20983..21474
                     /locus_tag="VVR39_000880"
     CDS             20983..21474
                     /locus_tag="VVR39_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6030393.1"
                     /translation="MTMPNIMMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELNQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21489..22268
                     /locus_tag="VVR39_000881"
     CDS             21489..22268
                     /locus_tag="VVR39_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6030394.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            22255..23073
                     /locus_tag="VVR39_000882"
     CDS             22255..23073
                     /locus_tag="VVR39_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6030395.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            23073..23366
                     /locus_tag="VVR39_000883"
     CDS             23073..23366
                     /locus_tag="VVR39_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6030396.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23388..25289
                     /locus_tag="VVR39_000884"
     CDS             23388..25289
                     /locus_tag="VVR39_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU6030397.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25349..26350
                     /locus_tag="VVR39_000885"
     CDS             25349..26350
                     /locus_tag="VVR39_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6030398.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26460..26795)
                     /locus_tag="VVR39_000886"
     CDS             complement(26460..26795)
                     /locus_tag="VVR39_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030399.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26806..27048)
                     /locus_tag="VVR39_000887"
     CDS             complement(26806..27048)
                     /locus_tag="VVR39_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030400.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(27059..27601)
                     /locus_tag="VVR39_000888"
     CDS             complement(27059..27601)
                     /locus_tag="VVR39_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU6030401.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(27617..27811)
                     /locus_tag="VVR39_000889"
     CDS             complement(27617..27811)
                     /locus_tag="VVR39_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6030402.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27977..28927
                     /gene="rsmH"
                     /locus_tag="VVR39_000890"
     CDS             27977..28927
                     /gene="rsmH"
                     /locus_tag="VVR39_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU6030403.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            28939..29256
                     /gene="ftsL"
                     /locus_tag="VVR39_000891"
     CDS             28939..29256
                     /gene="ftsL"
                     /locus_tag="VVR39_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU6030404.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            29260..31512
                     /gene="pbpX"
                     /locus_tag="VVR39_000892"
     CDS             29260..31512
                     /gene="pbpX"
                     /locus_tag="VVR39_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU6030405.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGVQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            31514..32494
                     /locus_tag="VVR39_000893"
     CDS             31514..32494
                     /locus_tag="VVR39_000893"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU6030406.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            33103..35208
                     /locus_tag="VVR39_000894"
     CDS             33103..35208
                     /locus_tag="VVR39_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6030407.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEAF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGATGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            35660..35826
                     /locus_tag="VVR39_000895"
                     /pseudo
     CDS             35660..35826
                     /locus_tag="VVR39_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        11273 a         5951 c         7773 g        10829 t
ORIGIN      
        1 tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga ttccatagaa
       61 tggggaagct agaactcttg tgtgaagagt ttgggtataa acttttacca cttcctccct
      121 actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag cacctcaaaa
      181 aggtattacc aagttgcaat accttttatg aggctctttt gtcctgctct tgtttcaatt
      241 gactataaat cgctataaga aaaaatcatt ttattggtat aaagaagtga ttgaaagtaa
      301 tggcgaaacg ttagataatt agttcataaa aaacaagttt agatcctcat ctaaacttgt
      361 ttttttaaaa ttgaaggatg attttggagg atataagatg acattgacta ttcatgtata
      421 ttataaaggt gatggagata gtgcaataaa gtttgcaaga gaaatgcttg atagtggcct
      481 tgttgaagaa attagaaatc aaaaaggtaa cttgaaatac gaatattttt taccaattga
      541 aaaagaggga actattctcc ttattgatca gtggataaat caagaagctt tagatgaaca
      601 tcatcaatca aagacaatgc agaaaatctt agatttaaga aaaaaatatc acttgcagat
      661 gcaagttgaa cgttatatag aagatgattc tgggatgcca gaaagcgata agtcgtttat
      721 agacacaggg aattagaatt attgtgagag tttttgtagt ttgaaagtat tgaaaatcgt
      781 aaagatatca ttacgagaat acaagaagat attgttctat ttccattaaa aattacttct
      841 ttccttaaca ataaggaaaa agaatgcgtt ttcatctttt gatttgaggt ttataataag
      901 agtatcaaag tcaggaggaa aaaagatgac tacttttaaa gatggatttt tatggggtgg
      961 tgctgttgct gctcatcaac ttgaaggtgg atggcaagaa ggtggcaaag gaattagtgt
     1021 tgctgatgtt atgactgctg gtcgccatgg agtagctcgt gaaattactt cgggagtttt
     1081 agagggtaaa tattatccaa atcatgaggc gatagatttt tatcatcgtt ataaagaaga
     1141 catagcactt tttgctgaaa tgggattcaa gtgcttccgt acctctattg catggacacg
     1201 tatctttcca aaaggtgatg agttagagcc gaatgaagaa ggattacagt tttatgataa
     1261 tctttttgat gaatgcttaa agaatggtat tgaacctgtc atcactctat ctcattttga
     1321 aatgccttat cacttagtga ccgaatatgg tggttggaaa aataggaaat tgattgattt
     1381 ctttgctcgt tttgcagaag tcgtatttaa acgttacaaa gataaggtta aatattggat
     1441 gactttcaat gaaatcaata atcaagcgaa ttataaggaa gattttgcac catttactaa
     1501 ctcaggtatt gtatatgagg aaggtgataa tagagaggca attatgtatc aagcagcaca
     1561 ttacgaatta gttgcttctg cacgagctgt aaaaattggt catgagatta atccagattt
     1621 tcaaataggt tgtatgattg cgatgtgtcc aatttatcca gctacttgca atcctaagga
     1681 tatcttaatg gcaatgaaag ctatgcagaa gcgttattat tttgctgatg tgcatgtttt
     1741 aggtaaatat cctgagcata ttttcaagta ttgggaacga aaaggtattt cagttgattt
     1801 tactgcccag gataaagaag atttacttgg tgggactgta gattacattg gtttcagtta
     1861 ctatatgtcc tttgctatcg actctcatcg tgaaaataat ccttattttg attatcttga
     1921 aacggaagat ttagtgaaaa ataattatgt taaggcttct gaatgggagt ggcaaattga
     1981 tccagaaggt ttgcgttatg cgttaaattg gtttacagac cactatcact taccactctt
     2041 tattgttgaa aatggttttg gagctataga tcaagttgca gcagatggta tggtacatga
     2101 tgattataga attgaatatc taggtgccca tattcgtgaa atgaaaaagg ctgtagttga
     2161 agatggtgtt gatttaatgg gttatactcc atggggatgt attgatttgg tttcagctgg
     2221 taccggtgaa atgcggaaac gttatggctt tatttatgta gataaagatg acaatgggaa
     2281 gggaagttat aatcgttccc cgaaaaaatc ttttggctgg tataaggaag ttatttcatc
     2341 taacggtgaa tcagtagaat agtataaaca aactgagatt attctcagtt tgtttagcat
     2401 attgaggtga catatgattg gaagtattgc agcaatttta acaacatttg catttttacc
     2461 acaagttttt cgtgtagtta agacaaagga cacaggatct attgctctag gtatgtatgt
     2521 tatgcaagtt attggtattg cattgtggct tgctcatggt attcgtatag gagacttgcc
     2581 tttgatttta gcaaatagtg tttcatttct actctcagga ataattttat tttataaatt
     2641 gaagtataaa taattttttt ccatatcatt taggaaaatg agggaattgt cattggaaac
     2701 gctttatttt ataataaaaa tagataacaa ataagccaac ttagcacagc tttgattgga
     2761 tttaagaaaa ggagaaaata ttatggcaaa agctttaatt atttgtgcag caggaatgtc
     2821 ttcatcactt atggcacaga aaacaacaga gtttctaaaa ggaaaaggga aagatattgt
     2881 agttgatgct attagtgcta ctgaaggagg gaaagctatc gcagcagcag cttttgattt
     2941 gtatcttgtc agccctcaaa caaaaatgta ctttaagcaa tttgaagagg ctggttctaa
     3001 agcaggaaaa ccagttgtac aaatacctcc tcaagcctat attcctattc caatgggaat
     3061 tgaaaaaatg gctaatttga ttcttgagaa tatttgatga acacatgaaa tgtcaataaa
     3121 tatttaagtt aagataaatt gttttgagtt tgatataaat tgatttaagt gtataatatg
     3181 cttcaatata tgaaaacata cgttttagga gggaatgaat gtgttaaaca ttaaagagaa
     3241 agatatcctt caatttttaa taaaaaataa ggaacgtttt gttacaagca aagaactggc
     3301 agaatattta tcctgttcag atagaactgt ccgtaatgta ctgaaattaa ttgagaagac
     3361 aatgattatt caaggagtcc ggttgatttc aaaacaaggt caagggtatc aaatattttt
     3421 tgagaatcaa ggcgcttacc aggagtttag acaaacttat gaactggaag aagactatac
     3481 gaaaactgcg gtttcaaaag gtgatgatcg tttagtattt atcttaaata aattattatt
     3541 tgagcaagtt ccagttcttt ttgatgattt agctgatgaa ctttacgtta gtcgttcaac
     3601 attatctcat gatttcagaa agatacgagt gatgttatca gagtataatt tgtccattga
     3661 gagtagggcg aataaaggag tttatgtctc aggcgaggaa cgtgataaac gacgttttat
     3721 cataaattat ttcctagaga atcaattttt taaaacaata cattgctatg taaaatttaa
     3781 cttttttgat caaactgttc cattagaaga atttgctaga attgttttgg atgaatgcca
     3841 agaggccaac ctaaaactat ctgattttgt actacagaat ttagtagttc acatagcatt
     3901 gtctgtgatt cgtttaaaat ccggatttga aataaaaaat atagactgtc agatgactga
     3961 tgatgcaata gagagaaagg ttgcccaaag aattctttct aaagtaagag aagtaacaaa
     4021 tcaggaattt ccagttcagg aaatagacta cattactttg catttgttag ctaagagtca
     4081 acaatgtcaa aaaaatcaga agaatatttc tgaagaagtt ttaaaaaaat ctttatttaa
     4141 aacatttcag aatttaggat tagatgatat gtataacttt tctttagatt tccaactaat
     4201 tgaaggattg ataactcatc taatgacact acaagtacgt ttagaaagcc ggattacctt
     4261 aaataaccct ttggtagatg aaattaaaca gaattatagt gatatattct ttatgactag
     4321 agaaattctt gcaaatatgg acaagttctt ggagtggaca atatcagatg atgaagtagc
     4381 atatgtaagt cttcactttt tagctgctat ggaacgtagc aaagagagta ctaagtttaa
     4441 tattcttgct atttgtgcaa caggatttgg tgcagcccaa atgttaagaa atcgtttgga
     4501 aacggagttt gggaagcgag tagaagttgt tgatgtaata ggctattatg aattgaatca
     4561 agaaaaactt aaaggaatag attttatagt gtcagctgtt gatttatcaa atctatattt
     4621 tcaaatccca gtttttaaag ttagtgtgtt tcttaagagt gatgagatgg aaatgattag
     4681 aaaagctatg gatcagatgc aagtttctag ttatgtacaa tcatcaaaga ttaacaaatt
     4741 tgaaaacaac agctttagac agtattttag taaagaaaat tttttaatat gtactgaatc
     4801 agacaaggta aatttacttg aaaagatggt tgagggttta tctgttggtg aatcaaatga
     4861 gtttgaacaa tctttacttt atggaattaa acagcgcgaa gaattaagtt cagttgtttt
     4921 ttctgaaaaa attgcagttc cgcatcctat tcagcccttt ggtacagagg gaaaggtttc
     4981 ggttgcaatc tgtaaagatt cgttactctg ggataatcaa agttcacatg tccagctagt
     5041 atttcttcta tctccatcaa tatatgggaa cgaaggtttg gcaactgtga ctaaaaagat
     5101 agtctctctg acagagaatg atgagttgca aaatcagcta atatcttgca ataactttga
     5161 agattttatt aacatatttg agaagataaa ataggaggtt catatgaatc aagaggaact
     5221 gcaggttgca gcatttgaaa ttatcctgca ttcgggaaat gcaaggtcag aaatacatga
     5281 agcatttgca aaaatgagag aaggtagttt tgatgatgca gaaagtaaat taaatcaatc
     5341 aaatgagata attcttgaag cgcatcatgc acaaaccaaa ctcttgcaag aatacgcaag
     5401 tggagtggaa attaaaattg aaattatcat ggtacatgct caagatcatt taatgaccac
     5461 tatgacatta ttagaagtag caaaggaaat gttagctctt tataagaaag ttaactaaat
     5521 atgtgttgtt atataaggag gaaatgatat ggataaaaaa gaacgacaaa agattgaaca
     5581 acaacgtcga gagatggctc taactaatac tttttttaat cgatatcttc ttctacgtta
     5641 ttcaatagca ctcttctttt ttgggaatat ttattggctt ttgaatcagt ttattagtcc
     5701 ctcgcctatt attattttcc ccattatgct catagtattt tctattttag caactattga
     5761 acaatttaaa ctttatggaa ataggaaaga aaagttggga ataacactaa tgtttgttag
     5821 aatacaaatg cttatttcaa taggattact tgttttaact tggacaagtt ggtttaagaa
     5881 tctttttccg atttttgaaa ataaccaagt agcacgttta tttgtttttg tagttcttct
     5941 attaggttta gttctgagtt tgttagacat tagaagaatt aaaaaaattt ataaacgaac
     6001 agataaggct tatcaacaat ttgtccaatt ggaaaagaac tcacttagtt tataatcctg
     6061 aactagtata atttgtattt gaaactagtc tttaaaaagt aaaaattatt atgttttatt
     6121 aaggaggtct atttatggat caacaaaacg ggttgtttgg ttttcttgaa aaccatgtta
     6181 tgggaccaat gggcaaactt gctcagttta aagtagtacg tgctatcacg attgcaggta
     6241 tggctgctgt accatttact attgtaggat caatgttttt ggtattcagt attttgccac
     6301 aagctttctc attttggcca attgtggcag atattttctc tgcttcattt gataaattca
     6361 catcacttta catggttgca aactatgcga ctatgggttc tctatctctt tatttcgttc
     6421 tatcacttgc atatgaattg acaaaaattt atgcagagga agaagaactc aatatgaatc
     6481 ctcttaatgg tgccttgctt gccttgatgg cttttgtcat gacagtaccg caaatcattt
     6541 ttgatggtgg aatgatgaag actgtgacaa gtctaaaaga aggtgcagta attgcagatg
     6601 gatgggcaat gggaaatgga gtcgcacgtt ttgggacaac agggattttt accgcaatca
     6661 ttatggcaat tgtgactgtt cttatttatc gtatgtgtgt taaacataat tgggttatta
     6721 aaatgcctga agctgttcca gaaggagttt ctcgtggatt taccgctttg gttccgggat
     6781 ttgttgttgc atttgttgtt atctttatca acggtcttct tgtagcaatg ggaacagata
     6841 tttttaaagt cattgcaatt ccatttggtt ttgtatccaa tctgactaat tcgtggattg
     6901 gtttaatgat tatttatcta ttgactcaac tactttggat tgtaggtatc cacggtgcga
     6961 acattgtttt tgcatttgtt agtccaattg ctcttgctaa catggctgaa aatgctgctg
     7021 gcgggcactt cgctgttgca ggtgaatttt ctaatatgtt tgtaattgca ggtggttctg
     7081 gtgcaacttt aggactatgt ttatatattg cttttgcctc taaatctgaa cagcttaaag
     7141 caataggacg agcatctgta gttccagcct tatttaatat taatgaacca ttaatttttg
     7201 gattacctat tatctataat ccagccttgg ctataccatt tattttagca ccaatggtta
     7261 ctgctactat ttattacgta gcgaattctc taaactttat taagccaatt atcgcacagg
     7321 ttccatggcc aactccagta gggattggag ctttcttagg gacagcagat cttcgagctg
     7381 tattagttgc tctagtatgt gcatttgcag cattcctagt ctatcttcca ttcatccgtg
     7441 tatatgatca aaaattggtg aaagaagagc aaggtatcta ataagtaaaa aagtatactc
     7501 gatgatagaa tccatatagt ttaaataatg agcgttaaca ttagcagtga agaggtcttt
     7561 ttaagatatt cttctctgct ttttcatatt ttttcgttat gtagggtatg aagcaaaata
     7621 gaaagtagtt cgaatagttg ataaacaggg aattgctgtt atttaaaaaa aacaataaag
     7681 taaagtatgt tatcgtagaa tacgatacaa tagtaaaaaa gcaaaaagaa tgcgttttat
     7741 atttgggttt gaggcttata aaataggata agcgtgctga aaacttagat atgacaaaca
     7801 aaataaaatt tttaaaagct acagagaaac atggtataat gcatctaaag gaggtagcat
     7861 atgtccttag atatagataa agaaaagatg acaatcatgg gaatagcttt tgaaaaccga
     7921 tccgttttta agagtgtttg gtatgcttta agtacaaata tgattgaagg atggcgacct
     7981 acggttagtg atgttgaaaa attacgagat gaagctcttg ctctggggat gacttaatga
     8041 agcgcaactg ttatgagtct tatgactatg ttgatccgga taatttatat accgatccgg
     8101 gttcttcagt tctaagaaat aagcaggaag gaaaaaagca cgcgagcttg aatatcgtat
     8161 gattgctagt aagagtttga aattatttat caatcctatc ttagttaata gtttaaaagt
     8221 agtttgtttc acaactgcat aagcttagaa aagttgaaaa gtgataactc tttaataaac
     8281 tcttggtttg ttaaaagata ttttgtccac tacatttttt tcaattgact attgtttgtc
     8341 atagatataa cagatagaac attgcattca gaataatgaa aaacgcatca aaaatggtgc
     8401 gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt aagggagagt
     8461 tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct caaactggaa
     8521 gttttgagga tagaacgaca caacttatct ataatagaga ttttggccaa atttcgttag
     8581 attatatcga gacatcaaac gtactagata ttatgacgga ctattttcat ctgcacttta
     8641 ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat tttgccgtat
     8701 atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca gctcggactc
     8761 tggataaggc agatggagca atctcgttag aagatggaat tattagccga aatggtatag
     8821 ccttattgga tgattctcaa ggatttattt gggatgaaca atctggttat attgagagag
     8881 aaaatcaaat tgacctgtat ttctttgcct atgggcatga ttatagagga gcaatcagag
     8941 atttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta ggcaattggt
     9001 ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac agatttgaaa
     9061 cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata actgacattc
     9121 cagctcgctt tggaagtggc tggacaggat atagttggaa tagaaactta ataccaaatc
     9181 cagaacagtt attgcaacaa cttcatgata gaaagctaaa actctcctta aatgtccatc
     9241 ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa cggttggggt
     9301 taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct tttaggaaag
     9361 cctactttaa agatgttcat tatgaactag aaaagcaggg agtagatttt tggtggattg
     9421 actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac cattatcact
     9481 atcaggatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat gcaggtcctg
     9541 gtagtcaccg ctaccctgtt ggtttttcag gggatactat tattagttgg aattccttaa
     9601 gatttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg tggagtcatg
     9661 atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga tggctacagt
     9721 ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt aatagtaaag
     9781 aaccttggtt tttttcagaa acaacatcta agattatgaa gaaatacctt cgtttgagac
     9841 atcagatgat tccctatcta tataccatga atgtaaagac acatgaggaa ggtgccccat
     9901 taatcagtcc aatctattat ttctatccag agaatgatga gagctataat gttccaaacc
     9961 aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg gatttgacat
    10021 tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac tttttttcag
    10081 ataaaaaata cacaggtggt gtgaagttaa gtgtttatag ggacatctcg actacgcctg
    10141 tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt atgggtgttg
    10201 atttacctga ggttgtagat tggtatgtat tcccagggaa acaacattct tttgaaatgc
    10261 ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg gaaatgggaa
    10321 tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga aaacatagaa
    10381 ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat gatacagcta
    10441 aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt agactactaa
    10501 agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc atcaatgcga
    10561 aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg agagggcgtt
    10621 tgttggaaat gatatttact agccaaaact aattgatata attagaaagt catttgttta
    10681 gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa atgtgaaata
    10741 agcacctaca acatagactt tacaacactt catgtttcat atcatggggt gtttttctat
    10801 ttaagtcaaa gccaatcaaa aactctcact attcatcagg ttaaaggaaa cctaatcata
    10861 gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt gggtctgttt
    10921 ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta gcgaaattcc
    10981 attcgattcg ttttcctagt gggccagatt tctggtcttg taaccagaca tagagagggt
    11041 ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt tgaaaatgta
    11101 ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata aactgattgc
    11161 aagggaaatc caatatttcg aagccttgat cttgatagcg ttcatagagt tcttgaagtc
    11221 cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag agaactttgc
    11281 cacgatagct atccaaggga gttgcttggt tgttttggtt caaaacggaa aaatcataaa
    11341 gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac ttttttcgtc
    11401 gagtcggatg gaagatattg ttgaagaata agccttcaat atgatagaaa ccgtttacaa
    11461 ataactttaa aaatggtatg atttaattaa accggtttac ttagttgcta taaatctcta
    11521 atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat acatgcaaac
    11581 aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat ttttattaaa
    11641 ccattatatg acagttggag cggaagaaac gactacgaat accattcagc aaagccagaa
    11701 ggaagttcag tatcagcaaa gggatacaaa aaatttagtt gaaaatggtg attttggtca
    11761 gacggaggac ggaagcagtc cgtggacagg aagcaaagct cagaggtggt cagcttgggt
    11821 agaccagaag aatagttctg cagatgcctc aactcgagtc attgaggcta aggatggggc
    11881 tatcactatc tcaagccctg agaaattaag ggcagcggtt caccgtatgg ttcctattga
    11941 agctaagaaa aagtataaac tgcgtttcaa gattaaaaca gatcataaag tcgggattgc
    12001 caaagttcgt atcattgagg aaagtggtaa ggacaagcga ttgtggaatt ctgcaacgac
    12061 gtcaggaaca aaggactggc agaccattga agcagactat agcccgactt tagatgttga
    12121 taaaatcaag ctggagttat tctatgaaac aggaactggg actgtttcct ttaaggatat
    12181 tgagctggta gaggtagcag accagctttc tgaggattct caaacagata aacagcttga
    12241 ggaaaagatt gatttaccaa ttggaaaaaa acatgttttt tctcttgcgg actatactta
    12301 taaggtagaa aatcctgacg ttgcttcagt caaaaatgga attttagaac ctcttaagga
    12361 agggacaacc aatgtcattg tcagtaaaga tggcaaggaa gtgaaaaaga ttcctttgaa
    12421 gattctagcc tctgttaagg atgcatacac agaccgtttg gatgactgga atggcatcat
    12481 tgctgggaat caatactatg attctaaaaa tgaacagatg gccaaattaa accaggaatt
    12541 ggaaggaaag gtagctgata gcctatctag tatttcaagt caggcggacc gcacctattt
    12601 gtgggaaaaa ttttcaaatt ataaaatgtc tgcaaatctg actgccactt atcggaaatt
    12661 ggaggagatg gccaagcaag tgaccaatcc ttcttctcgt tattatcaag atgaaactgt
    12721 cgttcgaaca gtcagggatt ccatggaatg gatgcataaa catgtctaca atagtgaaaa
    12781 gagcattgtt gggaactggt gggattatga aatcggtaca cctcgtgcca tcaacaatac
    12841 cttgtctctg atgaaagaat acttctctga tgaggaaatt aaaaaatata cagatgtgat
    12901 tgaaaaattt gtaccagatc ccgaacattt ccgaaagacg actgataacc cattcaaggc
    12961 tctaggtgga aacttagttg atatgggaag ggtaaaagta atagctggtt tactgcgtaa
    13021 ggatgatcaa gaaatttctt ctaccattcg ctcgattgag caagtgttca agttggtaga
    13081 ccaaggtgaa ggtttttatc aagatggatc ctatatcgac cataccaatg ttgcctatac
    13141 gggtgcttat gggaatgttt tgattgatgg cctgtctcaa ctgttgccag tcattcaaaa
    13201 gaccaagaat ccaatcgata aagataaaat gcaaaccatg taccactgga ttgataaatc
    13261 gtttgctcct ttgctggtga atggagagct gatggatatg agtcgtggac gctcgatcag
    13321 tcgtgcaaat agcgaggggc acgtggccgc agtagaagta ctaagaggga ttcaccgaat
    13381 agcggatatg tctgaaggag aaaccaaaca acgtttgcag agtcttgtga agaccattgt
    13441 tcaatcggat agttattatg atgtctttaa gaatttgaag acttataagg atatcagttt
    13501 gatgcaatcc ttgttaagtg atgcaggagt cgcaagtgtt ccaagaacaa gttacctatc
    13561 tgcctttaac aagatggata aaacagccat gtacaatgca gagaaagggt ttggatttgg
    13621 cttgtcactc ttttccagtc gtaccttgaa ttacgaacac atgaacaagg aaaataaaca
    13681 tggttggtat acgagtgatg ggatgttcta tctttacaat ggcgatttga gtcactatag
    13741 cgatggctac tggccaacag ttaatccata taagatgcct ggtacaacag agacggatgc
    13801 taagagagcg gatagcgata caggtaaagt tctaccgtct gctttcgttg gaacgagcaa
    13861 actagatgat gccaatgcga cagcaaccat ggatttcacc aactggaatc aaacattgac
    13921 tgctcataag agctggttta tgctgaagga taagatcgcc tttttaggaa gcaatatcca
    13981 aaacacttca acagatactg ctgcaactac aattgaccag agaaaactgg aatcaagtaa
    14041 tccatataaa gtctatgtca atgataaaga agcctccctt acagaacaag aaaaggatta
    14101 tcctgaaacc caaagtgtct ttttagaatc gtccgattcg aaaaagaata ttggttactt
    14161 tttctttaag aagagttcaa tcagtatgag taaggctttg caaaagggag cctggaagga
    14221 tatcaatgaa ggacagtcag acaaggaagt tgaaaatgaa tttcttacga ttagtcaggc
    14281 tcataagcaa aatggagatt cttatggcta tatgctcatc cctaacgtgg gtcgtgccac
    14341 cttcaatcaa atgataaaag agttagaaag tagcctcatc gaaaataacg aaacccttca
    14401 gtctgtttat gatgccaaac aaggagtttg gggcattgtg aaatatgatg attctgtctc
    14461 tactatttcc aaccaattcc aagttttgaa acgtggagtc tataccattc gaaaagaagg
    14521 ggatgaatat aagattgcct actataatcc tgaaacccag gaatcagctc cagatcagga
    14581 agtctttaaa aagctagagc aagcagctca gccacaagta cagaattcaa aagaaaagga
    14641 aaaatctgaa gaggaaaaga accattcgga tcaaaagaat ctccctcaga caggagaagg
    14701 tcagtcaatc ttggcaagtc tagggttctt gctacttggg gcgttttatt tattccgtag
    14761 aggaaagaac aactaatttg ttcatcatct agatgaatta catgaaactg tggaaaatag
    14821 aaaaaatccg aagaaggcca aatatcttcg gatttttctt ttaaaaaaga taagttgata
    14881 cttatctttt ttacttcatt atgtgactat agcgttttga aactagaata ggacgtcata
    14941 actgctaaaa gatttctata aattcatttg attttcctaa tcaatttgtt cgtatcctat
    15001 ttcactccac tatattagtc cgtctcgctc cgtgaggtgc gagacaaaac aaccacccgc
    15061 tatgcgggtg cgcgtcgaag gttataccaa aaaaactcca aacgcgatac aataaaggtg
    15121 ttcaatccac ttgtaaagcg aaaggagaaa aaatatggca caaaaggctc atagtttatc
    15181 tcacacaaag tggaggtgtt ctatcacatt gtgttcaccc ctaagtatag acgaaaagtc
    15241 atctataatc aatatagaag tagtttaggc gaaatatttc atcgcttgtg tagttataaa
    15301 ggtgttgaaa tgatcgaggg tcacttaatg ccagaccatg tacacatgtt agtcagtatt
    15361 ccactaaggc taagtgtttc gagtttcatg ggttatttaa aaggcaaaag tgcactcatg
    15421 atgtttgaca aacacgccaa tctcaagtac aagtttggga atcggcattt ctgggcggaa
    15481 ggttattatg taagtccagt agggcttaat gaagccacaa ttaagaaata tagtcaagat
    15541 taaagaaatt atccagtgga tgatttcttc acgagtatga aaatttgaga actagtaaag
    15601 tatgatatat agtaaaatga aataagaaca ggacaaaatc gatcaggaca gtcaaatcga
    15661 tttttaacaa tgttttagaa gtagaggtgt actattccag tttcaatcta ctatagcact
    15721 agataaattg agtgtaaaag aatatgagga tccctttagg gatagtggta agtaatacca
    15781 aagtctctta aagaggcaag tgacgagtca agagcaataa ggcttgaaca acgtgaaagc
    15841 cagcgtcttt aggcgctggc tgatgatttg ggcttatagc tctgagataa accacccgtt
    15901 agacgggtag ttatgatttt atctgagtgt aacatactgt tgggcaatct cgctgatgcg
    15961 gtcaaagttg ccttgggaag cgagtttatt gagttcgcca ccaattccaa cggcatctgc
    16021 accagcagcg aaccattgag ggatgttgtt taggccgact cctccggtta ccattacgga
    16081 aacttgtggg atcggtgcct tgactgcaga gatatatgct ggactgagag tactacctgg
    16141 gaagagtttg atgatttcac taccggcttc aagtgcagtc gtgatctctg tgagggtaat
    16201 acagcctgga atgtacggtg tgctgtagag attgcacatt ttcgcagttt cagcatggaa
    16261 agatggagaa acaacgtaat ttgctccagc tagaatggca tctctagcag ttacggcatc
    16321 aagcacagta cctgcaccga tacaaacact ctgatcgtcc tgatacaagt ctacaagttc
    16381 cttgatgatt tgtcctgcat actgattggt ataggcgatt tcaatagctt tgataccgcc
    16441 cttgatacaa gcaatcgagg cttgtagtcc ttcttccttt gtatttcctc gaatgacagc
    16501 gacaattttc tgttttttta gttcaataat cgtatctgat ttggtcatgt aattctccta
    16561 acgaatgata tcttgtgcat ttgccagtaa attttcaata ctagttgcgg aagtggagag
    16621 atggtctcct ggaagagtgc atttgagagt tgcgctcgca actgcaaagt caatggtagt
    16681 ttttagggag gaatgatgga gtagttggta aagggcacca gatataaagg catccccgct
    16741 accaattcgt tgatagactg cagtttttag ttggacagac tcttcaaatc gttcttccag
    16801 agcataggct tgatagacat ttttgtcttg ctcatcacta gatcggaggg tatggaaaat
    16861 agccttgaaa ccataggttt cttttaaaag tcgcatgcga ttttccacct cttctaggct
    16921 agcactgtct cttggaaaca tctctagatt ttggtcatca atcatgagag gatcaatacc
    16981 gaagcaatag tcagtaaaac gtgcaaactt agaaaattca tacttggctt ctagggctga
    17041 aatcatcttt gttctcagat tgagatccat tgaaacgaca attcctcggc gcttggcttc
    17101 ttccaagagt aggagaagga tcgcacggac ctcttgaccg atagctatgg tgattccact
    17161 aaaatgaaaa tggctaatcc cctgaaagag agaatccata tctagcatgt ttggccgaat
    17221 ctggctgata ctcgtatgct tacgatcgta gaaaacttca ctttgacgac aaccaaagcc
    17281 gttctccaaa tagtagaggc cgattcgatc gccaagccga cagattgaac tggtatcgat
    17341 ttggtgctgt ttcaagaatg tgagaaaacg atctccaatc tcgttggcag ggagtgcggt
    17401 aaagactttc gttgagatac ccagggcttg caaattacaa gcgatgttaa tttctgatcc
    17461 gccaaaataa gtcgaactgg caacatgatc gccgatactg gtggcatcta atggtgagat
    17521 tcgaattaat ggttcgccaa acagtaatat tttcgtcatc cattagttcc tttctggttt
    17581 agaatagctt tacttggcta atacttcttt caaataagca gcgacttcat catcttggca
    17641 gttttcaaag aagtattctt ggaagtattt gccagagatg gtgtctttga ggaagtcttg
    17701 gtcgattgtt ttaaggatgg tcatcaaatc attgtgggtg atttgtttca cctcgtttaa
    17761 gatacgagcg ttgcgttgtt cagggattac acgttctctt gggtagccac cgcccatttc
    17821 ttcagcaaat aagcgttcaa acatcaattt gagggtcagt tctgcccccc agccaaatcc
    17881 tttggcataa gggatagaca aggcgttacc accattgatt tgagaataaa ggtaagcgtc
    17941 agttgggtcc actgctagac cacagacaac accagggaag ctgtttaaag caagcatagc
    18001 ccctacaccc gtaccacagc cggtaacaac aaagtcaact gcctttgtat ttaaaaggat
    18061 ggcagccatt agtccgttct gcacataagt taattgactt tctccttctt ctccacgcat
    18121 accatagtta aataattggt agtctttttt atctgtcgct tcttttagac tatcgtaaat
    18181 aatgtgattc ttgctagctt gactattttc attgattaat gcgattttca taagatcttc
    18241 tttctatttt tactcaggtt gttttccgat gtaggctaag ataccgccat ctacatatag
    18301 gatgtggcca ttgacaaaat tgctggcatc actagcgaga aagacagcag ggcccatcaa
    18361 atcttcagga tttccccaac gtgcagcagg tgtttttgca atgatgaact ggtcaaatgg
    18421 gtggcgagaa ccatcttctt gcaactcacg aagaggtgct gtttgaggag tggcaatata
    18481 acctggtcca attccgttac attggatatt ggctccaccg tattcagacg caatgttgcg
    18541 ggtcaacatt ttcaagcccc ctttagcagc agcataagcg ctaactgttt cacgtcccag
    18601 ttcgctcatc atcgaacaaa tattgataat ctttccatgc cctttcttta tcatagaagg
    18661 aataactgcc tttgaaacga taaatggtgc gtttaagtca atatcgatga ccttacggaa
    18721 atcagcggcg ctcatttcgc acattggaac tcggcggata ataccagcgt tattaacgag
    18781 gatgtcaatg acaccaacct cttgttcgat ttgcttgacc atggcttgga taccgtcctc
    18841 gtctgtcacg tcacagacat atccatgggc ttcgatgcca acttcacgat aagcttcaat
    18901 ccctttattg accagatctt gattgatatc gttaaagaca atagtagcgc cggcttcagc
    18961 gtaggatttg gcaatagcaa atccaattcc ataagaagcg ccggtgatga gagcaatttt
    19021 tccttttaaa gaaaactgct caattgagaa tgatgtattt gtcatttgat acttcctttc
    19081 aaatttgtta agacttctct ataatcaaat tatattctag taaaccggtt ttgtcaataa
    19141 ataaatattt ttatttataa aaagatttat tttccttaaa aatggaatat tttgaaattt
    19201 ctgtctatta aaatgattaa aaagataatg aaagcgctaa tattttttta aaaaaactat
    19261 tgacaagata aaaataaagg attacaatgg ggaatataaa gtaaaccggt aaacctaaac
    19321 aagaaaggag aaaagatgaa aattgtactt gtagggcatg gacattttgc tacagggatt
    19381 tatagttctt tacaattgat tgcaggcaat caagaaaatg tggaggcgat tgactttgtg
    19441 gaaggaatgt cagcagatga actcaagcaa aaaatcttac ttgcaatttc aaatgaagaa
    19501 gaagttttaa tcctaagtga tctcttggga ggatcgccat tcaaggtttc ttctaccata
    19561 atgggagaaa atccagccaa aacaatgaat gttctctcgg gtttgaactt agccatgtta
    19621 atggaagcag tctttgctag aatggctcat agctttgatg aggttgttaa taaatcagta
    19681 gtggcggccc agggcggagt cgtaaatggt aaagaattgt tttcaacgga tgcagaggaa
    19741 gaggaagaag atttcgaatc gggtatttaa agggtaaaag aatgataaaa aaggttacga
    19801 ttgaaaaaat aaaatcgcct gagcgcttct tagaagtacc acttctgacg aaagaagaag
    19861 tcggccaggc aatcgataag gttattcggc agttagaact caaccttgac tatttcaagg
    19921 aagatttccc gacgccagct acctttgata atgtctatcc aatcatggat aacacggaat
    19981 ggaccaatgg tttctggaca ggagaactgt ggttggctta tgaatacagt caacaggatg
    20041 catttaaaaa catcgctcat aaaaatgttc tttctttcct ggatcgtgtc aataagagag
    20101 tagaattggc tcaccatgat ctcggcttct tgtacacacc gtcttgtatg gctgaatata
    20161 agataaatgg agatggagag gctagagaag cagccttgaa agctgcagat aagttgattg
    20221 aacgctatca agaaaaaggt ggttttattc aagcttgggg agacttgggc aagaaagagc
    20281 attaccgttt gattatcgat tgcttgctca atatccaact cttattcttt gcttatcaag
    20341 aaacaggcga tcaaaaatac tacgatattg cagaaagcca tttctatgct tcagctaata
    20401 atgtaatccg tgatgacgct tcgtccttcc acaccttcta ttttgatcct gagacaggtc
    20461 aaccctttaa aggtgtaacg agacaagggt atagtgatga ttcatgctgg gcacgtggtc
    20521 agtcatgggg agtttatggt attcctttga cttatcgtca cttaaaagac gagtcctgct
    20581 ttgacttgtt taagggtgtg accaattatt tcttgaatcg tctaccaaaa gatcatgtgt
    20641 cctattggga tttgattttt aatgatggta gtgatcaatc acgagattct tcagcaacag
    20701 ctatcgccgt ctgtgggatt catgaaatgc taaaacatct cccagaggtg gatgctgaca
    20761 aagatattta taaacatgct atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa
    20821 atgatcaatt tacccctggt gggacaagtc tcctccacgg tgtgtactca tggcattcag
    20881 gtaaaggagt ggatgaaggc aatatctggg gtgactacta ttacctagaa gcccttatcc
    20941 gtttctacaa agactggaac ctatattggt aggaggagaa atatgacaat gccaaatatt
    21001 atgatgaccc gtatcgatga acggttgatt catggacaag gacaactttg ggtaaaatac
    21061 ctaggttgta atacggtcat tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa
    21121 actctgatga aaacagttgt gccagactca gttgccatgc gtttcttccc tttgcaaaag
    21181 gtgattgata tcattcacaa ggctaatcct gctcaaacga tctttatcgt tgtaaaggat
    21241 gtgaaggacg ctttaacctt ggtagaaggt ggtgtcccta tcaaagaaat caatattggg
    21301 aacattcaca atgctactgg taaagagcaa gtgacacgct ccatcttcct gggtgaagag
    21361 gacaaggcgg ccctcaagga attgaaccaa actcatcaag taacatttaa tacgaaaaca
    21421 actccaacag gaaatgatgg agctgttcaa gtcaacatta tggactatat ttaaaagagg
    21481 agatcgttat gtcgattaat gtatttcaag cgattttaat tggattatgg acagctttct
    21541 gttttagtgg aatgctgtta ggaatttaca ccaatagatg tattgttctg tcatttggtg
    21601 tcggaattat tctaggtgat ctgcctactg ctcttgcaat gggagctatt ggtgaattgg
    21661 cttatatggg attcggtgtt ggtgctggag gtactgttcc accaaaccca atcggacctg
    21721 gtatctttgg taccttgatg gctatcacta gtgctggtaa agtcagtcca gaagcggctc
    21781 ttgccctctc tactccgatt gctgtggcga ttcaattctt acaaactttc gcctacactg
    21841 tacgtgctgg tgcgcctgaa acggcgatga agcacttgaa aaaccataat ttgaagaaat
    21901 tcaagttcac tctaaatgca acaatttggt tgtttgcctt tattggattt accttgggtt
    21961 gcttgggtgc cctttcaatg gataccttgt tgaaactcgt agactacatt ccaccggtat
    22021 tgcttacagg tttgacagtt gctggtaaaa tgctcccagc tatcggtttt gcgatgatct
    22081 tgtcagtgat ggctaagaaa gagttgattc cctttgtctt gttgggatat gtttgtgcag
    22141 cttatctaaa catcccaaca attggtattg caattgtagg tactatcttt gctttgattg
    22201 aattttataa caagccaaaa acagcggatc atgtggtaga ggaggaagca cacgatgact
    22261 ggatctaaca aattaacaaa acgtgattat cttaaaacgt ctttgcgggc attcttttgt
    22321 caaaatggat ttaactatag taactatcaa gggttgggat atgccaatgt gatgtatcct
    22381 gctttgaaaa aacactatgg agaggatcag gaaggtttct accaagcctt ggaagaaaac
    22441 tgtgaattct ataataccaa cccacacttc ctgcctttta ttaccagctt gcatcttgta
    22501 atgttggaaa atggccgtcc ggcaaaagaa acacgtagta tcaagatggc cttgatggga
    22561 ccattggcag gtattgggga ttctctttct caattctgtt tagctccatt gttctcaacc
    22621 atcgcagctt cgtttgctca agaaggcttg gttgtcggtc caatcttgtt cttccttgcg
    22681 atgaatacga ttttaacagc gattaaattg tcaactggtc tgtatggata caaactagga
    22741 acaactgtga ttgataaact aagcgaacag atggcaacga tttctcgtat tgccaatatt
    22801 atcggtgtaa ccgtaattgc tggtttggca gcgacatctg ttaagattat ggtgccgatt
    22861 acctttgctg caggggaagt taaagcagac gctaaacaaa gtatcgtaag tattcaggga
    22921 atgcttgata aggttgctcc agctcttcta ccagccctat ttacactttt agtttactac
    22981 ttgatcaaag aaaagaaatg gacaacatat aaactcgtta ttttaacagt tatcatcgga
    23041 attatcggaa gctggcttaa gattatagct taatggatac aacattgttt tatggaatag
    23101 tgattgtctt ggcagtgagt ccccttttac tgtcaagctt tcattctatt cgtcagcaaa
    23161 agttgcttcg caaacagatg gagcaacgac aagagtattt agcttcttta acatctggtg
    23221 atgaagtgtt gttattgtct ggaattcatg gaaaaatcat ttctatccaa gatgacttgg
    23281 tctccttgca gattgcaaaa ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa
    23341 agacaaaaga actgcttttt aagtagttct ttttctggta atagataatg aaagaagaaa
    23401 gaagacaatt ttttgaaaga atcgatggaa accaatgtcg tgattatatc ttgtcgcact
    23461 gttcaaaaga ctatgagaaa gtcaagagtt cccttgaacg cttgatggac aatcgtttta
    23521 tgtttgatag tccttgggat atggagcctt gttcaaaaat ccatcaaatc cagccgatgg
    23581 tatgggatca agtatttgaa gatgatccag aatgggctta tatgctcaat cgacaagaat
    23641 atctcttgca gtttatgata gggtatgtgg tagaaggaga taaggactat attcaaaagt
    23701 gcaagttctt tctatttgat tggattgagc aggtgagaga attttctcct caatccttga
    23761 tgactagaac cttggatacg ggtattcgtt cctttacttg gttgaaacta ctcttgcttc
    23821 tcttgaaatt tgacttgcta gaggagaaag aactagagaa aattttggtc agtctagaaa
    23881 agcagattga ctttatgaaa agctactatc gcgccaagta cacccttagt aactggggga
    23941 ttttacaaac aattccgatg cttgctatct atcatttctt ttcagataag atggacctag
    24001 aagaagctta ccattttgct tcagaggagt tgaaacagca aattgagaca cagattttag
    24061 gagatggaag ccagtttgaa cagtcgattc tctatcatgt agaggtttat aaagccttgc
    24121 tggatttgtg tctcttgctt ccagacttgc aagatagtta ccaagagttg ctggaaaaga
    24181 tggcgaccta tattcaaatg atgacaggct tagatggacg gactttggct tttggtgata
    24241 gcgattctac agaaacgaca gaaatgttga gcctgtctgc tgtggttttg aacaaggaag
    24301 accttcttaa cggtctggat gttaaagttg atttgcttag cctcttgttc ctggggcgag
    24361 aaaaggtcaa gcgactgcag gaatttgaaa ggagagcttg gcagcctaag tccatgatct
    24421 ttgaagactc tggacatgtc tgcattaagg atgaacatcg ttatctattt ttcaaaaatg
    24481 gtccgctagg aagtgcccat agccatagtg acgagaatag tttttgctta cagtatcaag
    24541 gccaacctat tttcatagat gctgggcgtt attcttatcg ggagatatat gaacgttatc
    24601 tcttaaagag tgcttggagt cattcgacct gcattgtaga tgggaaagct ccggaaagaa
    24661 tcacgggatc ctgggaatat gaatactatc ctcactccct gttttgtcac cataaagaaa
    24721 gggagggagt gcattatatt gagggggctt attggtcagc agaacctgat ttgccttatc
    24781 ttcacaagag aaaaatcctc atgttggtag aggatgtctg gctcttggta gatgacatca
    24841 ggtgtcaagg tcagcatgag gcgttgattc agtttatcct tgacaaggat gtgacctatc
    24901 aagatgggaa aatcaatcag ttgagactat ggagtgaagt tgattttgat ttggaagata
    24961 ccatcatttc tcctaaatac aatgagcttg aaagaagtag caaactcacc aagcgccaat
    25021 tctttgagaa tcagatgctg gattatacca tcattgcgca tgagagtttt gaaatcatcc
    25081 gtcattctgt ctaccagaca gatgatcgtg aagtggaaaa tgctctggct tttgaagtga
    25141 aaaatgacga aacagacaag ctgattctgt tattaagcga ggatattggt gtaggtgaaa
    25201 aattgtgcct cgttgacgga acaaaaatgc gtggaaaatg tctagtatat gataaaataa
    25261 atgagagaat gattcgcttg cagtgctaga aataggcatt ttgaatagtg aacatgttat
    25321 aataagtatt agtaggaggt gttttagatt ggagaagaaa ctgaccataa aagacattgc
    25381 ggaaatggct cagacctcga aaacaaccgt gtcattttac ctaaacggga aatatgaaaa
    25441 aatgtcccaa gagacacgtg aaaagattga aaaagttatt catgaaacaa attacaaacc
    25501 gagcattgtt gcgcgtagct taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg
    25561 tgatattacc aacagtttct caaaccaaat tgttaaggga attgaggata tcgccagcca
    25621 gaatggctac caggtaatga taggaaatag taattacagc caagagagtg aggaccggta
    25681 tattgaaagc atgcttctct tgggagtaga cggctttatt attcagccga cctctaattt
    25741 ccgaaaatat tctcgtatca tcgatgagaa aaagaagaaa atggtctttt ttgatagtca
    25801 gctctatgaa caccggacta gctgggttaa aaccaataac tatgatgccg tttatgacat
    25861 gacccagtcc tgtatcgaaa aaggttatga gcattttctc ttgattacag cggatacgag
    25921 tcgtttgagt actcggattg agcgggcaag tggttttgtg gatgctttaa cagatgctaa
    25981 tatgcgtcac gccagtctaa ccattgaaga taagcatacg aatttggaac aaattaaaga
    26041 atttttacaa aaagaaatcg atcccgatga aaaaactctg gtatttatcc ctaactgttg
    26101 ggccctacct ctagtcttta ccgttatcaa agagttgaat tataacttgc cgcaagttgg
    26161 gttgattggt tttgacaata cggagtggac ttgcttttct tctccaagtg tttcgacgct
    26221 ggttcagccc tcctttgagg aaggacaaca ggctacaaag attttgattg accagattga
    26281 aggccgcaat caagaagaaa ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc
    26341 gactttctaa aatgaaggaa aatgacttgc aatctctgtt aagaaataaa ataatcccac
    26401 ctagaacaag ctaggtggga ttatttgcct atgaaatgag aaattatggg agcaagctcc
    26461 taaatcaact gtttttgatc tacttcttta actacttgat aaaagttata gaagtaggcc
    26521 aaacttgaaa tgatggttac gactaggaat attgaaaatt tccattggac agggttggtt
    26581 aaaagttgtg gaaaggatat gaggagaaag aagagggctg cgttgaggac aggtatccgt
    26641 tttgattgta ttttctcaag tcctttattg agcgcaggaa gaaagaggag taggagtagt
    26701 aaaactgtat gagaaacagc tcctgaaata agggcaaaga aaaggaaaat actgataaaa
    26761 acatgaatga tcagtagtct agctagtgat ttcataaggt acctcctaat cctggtcttt
    26821 tttagctctt gcaatacgaa gtgagtcgac aatatgtatc atcactccga aaaagaaagc
    26881 tcccagtata gttttaaaaa tatgttttgt atttagaaga gaactgataa aatttggatt
    26941 ttcacttgtt agggtatcaa tgagtggaat tataaaaaat atcactgttc cataaatcga
    27001 acctgctttc agaccaggat aacgtaactg tctcttttct tttttcatga gtttcctcct
    27061 aatcctcatc ttgatttttc ttagtttttg caatgcgacg ggagatgagg aactgtatgc
    27121 tcgctccgaa gaaaatagaa ccgagaatgc ttgatacacc atttcttata gtgagaagag
    27181 aatgaaaata gtcctgacct tcatctatga gtatactgag aagaggagtt ataaaaaaca
    27241 tccatagacc aaagaacaaa cctgctttca gacctgggta gtgtagttgc ttgctttctt
    27301 tctcattcag catatctggt tcaatgactg tgatgcctgt ttttttcatt tggtaggtga
    27361 catagccaga agcgatgagg gcaatcacta aaatcagagg gggatagatt agagccactt
    27421 cttgagggta tttataggct agaaggagtg gaataatatt tccgaaaatc atcagataaa
    27481 agaggacgat aaagacttgg ttcccaatac tatcggcctc acgccgtttg tattcgtcaa
    27541 ggggaccaga aataccgtat gtgcgtttga tcagtttttc agtgaaggtt tcttttttca
    27601 tgagtttgct ccttttttaa aaatcttcct cccaaaagag actgttgagg tcagtttgga
    27661 ggctgcgggc gagattgaga cagagttcca aggttggatt gtacttgtcg ttttcaatca
    27721 tattgatagt ctgtctcgag acaccgatat ccttggcgag ttcgagctgg gaaataccca
    27781 attccttgcg aaattctttc acacgattca tctggtctcc tttctgattt atgtcgtata
    27841 tatttgacta tattatagtc ttttaaacat aaagtgtcaa gtatttttga catatttttt
    27901 gaagaaatag tagtctcctt gtcctatttg tctgacaagt gcaagctggt cggatttgtg
    27961 gtaaaataga taagatatga caaaagaatt tcatcatgta acggtcttac tccacgaaac
    28021 gattgatatg cttgacgtaa aacctgacgg tatctacgtt gatgcgactt tgggtggagc
    28081 aggccatagc gagtatttat taagtaaatt aagtgaaaaa ggccatctct atgcctttga
    28141 ccaggatcag aatgccattg acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg
    28201 aatggtgacc tttatcaagg acaacttccg tcatttacag gcacgtttgc gcgaagctgg
    28261 tgttcaggaa attgatggaa tttgttatga cttgggagtg tctagtcctc aattggacca
    28321 gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg gacatgcgga tgaatcagga
    28381 tgctagtctg acagcctatg aagtggtgaa caattatgac tatcatgact tggttcgtat
    28441 tttcttcaag tatggagagg ataaattctc taaacagatt gcgcgtaaga ttgagcaagc
    28501 gcgtgaagtg aagccgattg agacaacgac tgagttagca gagattatca agttggtcaa
    28561 acctgccaag gaactcaaga agaagggtca tcctgctaag cagattttcc aggctattcg
    28621 aattgaagtc aatgatgaac tgggggcggc agatgagtcc atccagcagg ctatggatat
    28681 gttggctctg gatggtagaa tttcagtgat tacctttcat tccttagaag accgcttgac
    28741 caagcaattg ttcaaggaag cttcaacagt tgaagttcca aaaggcttgc ctttcatccc
    28801 agatgatctc aagcccaaga tggaattggt gtcccgtaag ccaatcttgc caagtgcgga
    28861 agagttagaa gccaataacc gctcgcactc agccaagttg cgcgtggcca gaaaaattca
    28921 caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa caggtcaaat actacagatg
    28981 caacttaaac ggttttcgcg tgtggaaaaa gctttttact tttccattgc tgtaaccact
    29041 cttattgtag ccattagtat tatttttatg cagaccaagc tcttgcaagt gcagaatgat
    29101 ttgacaaaaa tcaatgcgca gatagaggaa aagaaaaccg aattggacga tgccaagcaa
    29161 gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg
    29221 caattaaaca atgaaaatat tagaatagcg gagtaagata tgaagtggac aaaaagagta
    29281 atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa acagacgcag agttggaaaa
    29341 agtctgagtt tattatctgt ctttgttttt gccatttttt tagtcaattt tgcggtcatt
    29401 attgggacag gcactcgctt tggaacggat ttagcgaagg aagctaagaa ggttcatcaa
    29461 actacccgta cagttcctgc caaacgtggg actatttatg accgaaatgg agtcccgatt
    29521 gctgaggatg caacctccta taatgtctat gcggtcattg atgagaacta taagtcagca
    29581 acgggtaaga ttctttacgt agaaaaaaca caatttaaca aggttgcaga ggtctttcat
    29641 aagtatctgg acatggaaga atcctatgta agagagcaac tctcgcaacc taatctcaag
    29701 caagtttcct ttggagcaaa gggaaatggg attacctatg ccaatatgat gtctatcaaa
    29761 aaagaattgg aagctgcaga ggtcaagggg attgatttta caaccagtcc caatcgtagt
    29821 tacccaaacg gacaatttgc ttctagtttt atcggcctag ctcagctcca tgaaaatgaa
    29881 gatggaagca agagcttgct gggaacctct ggaatggaga gttccttgaa cagtattctt
    29941 gcagggacag acggcattat tacctatgaa aaggatcgtc tgggtaatat tgtacccgga
    30001 acagaacaag tttcccaacg aacgatggac ggtaaggatg tttatacaac catttccagc
    30061 cccctccagt cctttatgga aacccagatg gatgcttttc aagagaaggt aaaaggaaag
    30121 tacatgacag cgactttggt cagtgctaaa acaggggaaa ttctggcaac aacgcaacgg
    30181 ccgacctttg atgcagatac aaaagaaggc attacagagg actttgtttg gcgtgatatc
    30241 ctttaccaaa gtaactatga gccaggttcc actatgaaag tgatgatgtt ggctgctgct
    30301 attgataata atacctttcc aggaggagaa gtctttaata gtagtgagtt aaaaattgca
    30361 gatgccacga ttcgagattg ggacgttaat gaaggattga ctggtggcag aatgatgact
    30421 ttttctcaag gttttgcaca ctcaagtaac gttgggatga ccctccttga gcaaaagatg
    30481 ggagatgcta cctggcttga ttatcttaat cgttttaaat ttggagttcc gacccgtttc
    30541 ggtttgacgg atgagtatgc tggtcagctt cctgcggata atattgtcaa cattgcgcaa
    30601 agctcatttg gacaagggat ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct
    30661 attgctaatg acggtgtcat gctggagcct aaatttatta gtgccattta tgatccaaat
    30721 gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa atcctgtttc taaagatgca
    30781 gctagtctaa ctcggactaa catggttttg gtagggacgg atccggttta tggaaccatg
    30841 tataaccaca gcacaggcaa gccaactgta actgttcctg ggcaaaatgt agccctcaag
    30901 tctggtacgg ctcagattgc tgacgagaaa aatggtggtt atctagtcgg gttaaccgac
    30961 tatattttct cggctgtatc gatgagtccg gctgaaaatc ctgattttat cttgtatgtg
    31021 acggtccaac aacctgaaca ttattcaggt gttcagttgg gagaatttgc caatcctatc
    31081 ttggagcggg cttcagctat gaaagactct ctcaatcttc aaacaacagc taaggctttg
    31141 gagcaagtaa gtcaacaaag tccttatcct atgcccagtg tcaaggatat ttcacctggt
    31201 gatttagcag aagaattgcg tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg
    31261 aagattaaaa acagttctgc tgaagaaggg aagaatcttg ccccgaatca gcaagtcctc
    31321 atcttatctg ataaagcaga ggaggttcca gatatgtatg gttggacaaa ggagactgct
    31381 gagacccttg ctaagtggct caatatagaa cttgaatttc aaggctcggg ctctactgtg
    31441 cagaagcaag atgttcgtgc taacacagct atcaaggaca ttaaaaaaat tacattaact
    31501 ttaggagact aatatgttta tttccatcag tgctggaatt gtgacatttt tactaacttt
    31561 agtaggaatt ccggccttta tccaatttta tagaaaggcg caaattacag gccagcagat
    31621 gcatgaggat gtcaaacagc atcaggcaaa agctgggact cctacaatgg gaggtttggt
    31681 tttcttgatt acttctgttt tggttgcttt ctttttcgcc ctatttagta gccaattcag
    31741 caataatatg ggaatgattt tgttcatctt ggtcttgtat ggcttggtcg gatttttaga
    31801 tgactttctc aaggtctttc gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc
    31861 tcttcagctt ctaggtggag ttatcttcta tcttttctat gagcgcggtg gcgatatgct
    31921 ttctgtcttt ggttatcaag tgcatctagg gattttctat attgtcttcg ctcttttctg
    31981 gctagtcggt ttttcaaacg cagtaaactt gacagacggt gttgacggtt tagctagtat
    32041 ttccgttgtg attagtttgt ctgcctatgg agttattgcc tatgtgcaag gtcagatgga
    32101 tattcttcta gtgattcttg ccatgattgg tggtttgctc agttttttca tctttaacca
    32161 taagcctgct aaggtcttta tgggtgatgt gggaagtttg gccctaggtg ggatgctggc
    32221 agctatctct atggctctcc accaagaatg gactctcttg attatcggaa ttgtatatgt
    32281 ttttgaaaca acttctgtta tgatgcaagt cagttatttc aaactgacag gtggtaaacg
    32341 tattttccgt atgacgcctg tacatcacca ttttgagctt gggggattgt ctggtaaagg
    32401 aaatccttgg agcgagtgga aggttgactt cttcttttgg ggagttgggc ttctagcaag
    32461 tctcctgacc cttgcaattt tgtatttgat gtaagaatgg caccctgatg tttcagggtg
    32521 tttttgtgtt taaatacaca atgaaaatca aagaacaaac tagaaagcta actttaggct
    32581 gctcaaaata tagtagattg aaactagaat agtacacctc tacttctaaa acatttttag
    32641 aaatcgattt gactgtcctg attgatttgt cctgttctta tttcatttta ttatacagtt
    32701 ttgagatggt tgatagaact gacgaagtca gctcaaaaca cggttttgag gttgtagata
    32761 aggagaagct gatgtagttt gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt
    32821 aaagtcaaaa cccttgacct tttctgacca atgtagtata ttatgaacgt aaggtaaatg
    32881 aaagccttac tagaacactt atttaaagta aaatagaaag aggtgggtct atgtttcatc
    32941 tagaaatctt cagaagtaaa gatagtctac tcctgcttga aaaagaaaaa ccagaaatag
    33001 tacgtagggt agcgatctag ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa
    33061 tatcagtaat cataactaag taaacaaaaa gaggtaaaga atatgaataa caactttaat
    33121 aattttaata acatggatga tttatttaac caattgatgg gtggtatgcg aggatacagt
    33181 tctgaaaatc gccgttactt aattaatgga cgcgaagtca cacctgaggc atttgctcac
    33241 tatcgtgcga ctggtcaatt accaggaaat gcagaaactg atgtgcaaat gccccaacag
    33301 gcatcaggta tgaaacaaga cggtgtcctt gcaaaactag gtcgaaactt aacagcagaa
    33361 gcgcgtgagg gcaagttgga tcctgttatc ggacgaaaca aggaaattca agaaacatct
    33421 gaaatcctct cacgccgcac caagaacaat cctgttttgg tcggagatgc aggtgttggt
    33481 aagacagcag ttgtcgaagg tctagcgcaa gccattgtga acggagatgt tcctgctgct
    33541 atcaagaaca aggaaattat ttctattgat atctcaggtc ttgaggctgg tactcaatac
    33601 cgtggtagct ttgaagaaaa tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat
    33661 attatcctct tctttgatga aattcaccaa attcttggtg ctggtagcac tggtggagac
    33721 agtggttcta aaggacttgc ggatattctc aagccagctc tctctcgtgg agaattgaca
    33781 gtgattgggg caacaactca agacgaatac cgtaacacca tcttgaagaa tgctgctctt
    33841 gctcgtcgtt tcaacgaagt gaaggtcaat gctccttcag cagagaatac ttttaaaatt
    33901 cttcaaggca ttcgtgacct ctatcaacaa caccacaatg tcatcttgcc agacgaagtc
    33961 ttgaaagcag cggtggatta ttctgttcaa tacattcctc aacgtagctt gccagataag
    34021 gctattgacc ttgtcgatgt aacggctgct cacttggcgg ctcaacatcc agtaacagat
    34081 gtgcatgctg ttgaacgaga aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa
    34141 gcagaagatt ttgaagcagc tctaaactat aaaacacgca ttgcagaatt ggaaaggaaa
    34201 atcgaaaacc acacagaaga tatgaaagtg actgcaagtg tcaatgatgt ggctgaatct
    34261 gtggaacgaa tgacaggtat cccagtatcg caaatgggag cttcagatat cgaacgtttg
    34321 aaagatatgg ctcatcgctt gcaagacaag gtgattggtc aagataaggc cgtagaagtt
    34381 gtagctcgtg ctatccgtcg taaccgtgct ggttttgatg aaggaaatcg cccaataggc
    34441 agcttcctct ttgtaggggc tactggggtt ggtaagacgg agcttgctaa gcaattggca
    34501 ctcgatatgt ttggaaccca ggatgcgatt atccgtttgg atatgtctga atacagtgac
    34561 cgcacagctg tttctaagct aattggtaca acagcaggct atgtgggtta tgatgacaat
    34621 agcaatacct taacagaacg tgttcgtcgc aatccatact ctatcattct cttggatgaa
    34681 attgaaaagg ctgatcctca agttattacc cttctcctcc aagttctaga tgatggtcgt
    34741 ttgacagatg gtcaaggaaa tacagtaaac ttcaagaaca ctgtcattat tgcgacctca
    34801 aatgctggat ttggctatga agccaacttg acagaagatg cggataaacc agaattgatg
    34861 gaccgtttga aacccttctt ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag
    34921 ttctcgcact tgactaagga agacctttct aagattgtag atttgatgtt ggctgaagtt
    34981 aaccaaacct tggctaagaa agacattgac ttggtagtta gtcaagcggc taaagattat
    35041 atcacagaag aaggttacga cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa
    35101 caagaaattc gtgataaggt gacagacttc cacttagatc atttagatgc taaacatctg
    35161 gaagcagata tggaagatgg cgttttggtt attcgtgaga aagcctaaga tagaattttg
    35221 aggataaaaa agaaggagcc agctgaaaaa aactggttcc ttttgaggta cgacgggcat
    35281 gtcgtacagt gggttgaaac tagaatagta cacatctact tctaaaatat tgttagaaat
    35341 cgatttgact gtcctgattg atttgtcctg ttcttatttc attttactat atatctgagg
    35401 tgtaagtcct cggtgggtac ctgctaccgg tgctcccaat agtgattccc aagcctgact
    35461 atcgtgaggt agcggattaa aacggtctgg ggatagaccg ttttaagtct gacgctggaa
    35521 ataagaatcg tcagaggaag ggatagcgaa atcgtggctc tacgaatagg aacgtgataa
    35581 taaggcgtat atagcggata aggggcctca aactctaaag ttcaaaaagg tagtcgtagc
    35641 ctatatgtgt aaatcacgag agcaactgaa tttgtctgtt cgaggatgga taaactattt
    35701 ctcattggga aatatgaaaa gtatagtcac tagcatagat gagcgcttgc atactcgcct
    35761 acgagtgatt atctggaagc aatggaagaa aaaatcgaga cgattatggg gattgcttaa
    35821 gttagg
//
LOCUS       DAVHSL010000018        34480 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000018 DAVHSL010000000
VERSION     DAVHSL010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.018"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            592..1044
                     /locus_tag="VVR39_000896"
     CDS             592..1044
                     /locus_tag="VVR39_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6030408.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1063..2400
                     /locus_tag="VVR39_000897"
     CDS             1063..2400
                     /locus_tag="VVR39_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6030409.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2479..3363
                     /locus_tag="VVR39_000898"
     CDS             2479..3363
                     /locus_tag="VVR39_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6030410.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3363..4196
                     /locus_tag="VVR39_000899"
     CDS             3363..4196
                     /locus_tag="VVR39_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6030411.1"
                     /translation="MKKKSGIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4215..6308
                     /gene="nanB"
                     /locus_tag="VVR39_000900"
     CDS             4215..6308
                     /gene="nanB"
                     /locus_tag="VVR39_000900"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU6030412.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6320..7423
                     /locus_tag="VVR39_000901"
     CDS             6320..7423
                     /locus_tag="VVR39_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6030413.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVRLSEIVK"
     gene            7597..8295
                     /locus_tag="VVR39_000902"
     CDS             7597..8295
                     /locus_tag="VVR39_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6030414.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEVGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8314..9831
                     /locus_tag="VVR39_000903"
     CDS             8314..9831
                     /locus_tag="VVR39_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6030415.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRSLGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9956..11284
                     /locus_tag="VVR39_000904"
     CDS             9956..11284
                     /locus_tag="VVR39_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6030416.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11536..12402
                     /locus_tag="VVR39_000905"
     CDS             11536..12402
                     /locus_tag="VVR39_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6030417.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12418..13257
                     /locus_tag="VVR39_000906"
     CDS             12418..13257
                     /locus_tag="VVR39_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6030418.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13530..13982
                     /locus_tag="VVR39_000907"
     CDS             13530..13982
                     /locus_tag="VVR39_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6030419.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14079..14423
                     /locus_tag="VVR39_000908"
     CDS             14079..14423
                     /locus_tag="VVR39_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030420.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            14710..15354
                     /locus_tag="VVR39_000909"
     CDS             14710..15354
                     /locus_tag="VVR39_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6030421.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15523..16440
                     /locus_tag="VVR39_000910"
     CDS             15523..16440
                     /locus_tag="VVR39_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU6030422.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16458..17342
                     /locus_tag="VVR39_000911"
     CDS             16458..17342
                     /locus_tag="VVR39_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6030423.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17358..18209)
                     /locus_tag="VVR39_000912"
     CDS             complement(17358..18209)
                     /locus_tag="VVR39_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6030424.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18409..20466
                     /gene="pbp2b"
                     /locus_tag="VVR39_000913"
     CDS             18409..20466
                     /gene="pbp2b"
                     /locus_tag="VVR39_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU6030425.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20477..21073
                     /gene="recR"
                     /locus_tag="VVR39_000914"
     CDS             20477..21073
                     /gene="recR"
                     /locus_tag="VVR39_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU6030426.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21249..22292
                     /locus_tag="VVR39_000915"
     CDS             21249..22292
                     /locus_tag="VVR39_000915"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU6030427.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFIVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAEAAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22376..23749
                     /locus_tag="VVR39_000916"
     CDS             22376..23749
                     /locus_tag="VVR39_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU6030428.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23736..24347
                     /locus_tag="VVR39_000917"
     CDS             23736..24347
                     /locus_tag="VVR39_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6030429.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24438..25142
                     /locus_tag="VVR39_000918"
     CDS             24438..25142
                     /locus_tag="VVR39_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU6030430.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGAHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25361..26734
                     /gene="ftsA"
                     /locus_tag="VVR39_000919"
     CDS             25361..26734
                     /gene="ftsA"
                     /locus_tag="VVR39_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU6030431.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26751..28010
                     /gene="ftsZ"
                     /locus_tag="VVR39_000920"
     CDS             26751..28010
                     /gene="ftsZ"
                     /locus_tag="VVR39_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU6030432.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28015..28686
                     /locus_tag="VVR39_000921"
     CDS             28015..28686
                     /locus_tag="VVR39_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU6030433.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28696..29235
                     /locus_tag="VVR39_000922"
     CDS             28696..29235
                     /locus_tag="VVR39_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU6030434.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29235..29498
                     /locus_tag="VVR39_000923"
     CDS             29235..29498
                     /locus_tag="VVR39_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU6030435.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29495..30280
                     /locus_tag="VVR39_000924"
     CDS             29495..30280
                     /locus_tag="VVR39_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU6030436.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30289..31077
                     /gene="divIVA"
                     /locus_tag="VVR39_000925"
     CDS             30289..31077
                     /gene="divIVA"
                     /locus_tag="VVR39_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU6030437.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLVQLAQCMKNQK"
     gene            31425..34217
                     /locus_tag="VVR39_000926"
     CDS             31425..34217
                     /locus_tag="VVR39_000926"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU6030438.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYQNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10610 a         6064 c         7513 g        10293 t
ORIGIN      
        1 aaaaaaaaaa gtatactcta attgaaaacg gtaacaaaac taatttagag aatgaaatat
       61 agagtatttc tctcttaaaa gtttttggtg aaacgagatg tagaaaggag atttagccaa
      121 agagtctatt agtgctagaa taatagatta gaattatttt agaaaaacga agtgagcagc
      181 ttataaattc aagtccccaa atagattcat actagtatct tttgcaaaaa ataaagggcg
      241 acttccttca tgaatatcaa tttcatctat aaggaaggta gctaattgaa ctaacttatt
      301 tattctgttt gtcgctagaa aaatcagacc tccttgtgaa gattgaggag atactgaatg
      361 aaaatcaaag aagaaactag caagctagta gcagattgcc caaaacaccg ctttgaggtt
      421 gtagataaga ctgacctata taatccaagg tgaagcgact gtggtttgaa gagattttca
      481 aagagtatag gctagagagt agtgttttta tgtccttcta gtagaaaatg ctagacagaa
      541 gaatggggaa cttggatagg aaaaatagat tgagaaagga ggttagaaga gatgattatt
      601 acaaaaatta gccgtttagg aacttatgtg ggagtcaatc cacattttgc aacattaata
      661 gattttctag aaaaaacagg actagaaaat ttaacagaag gttcgattgc tatcgatggt
      721 aatcgattgt ttgggaattg ctttatttat ctagcagatg gtcaagcagg ggctttcttt
      781 gaaacacacc aaaaatattt ggatattcat ttagttttgg aaaacgaaga agccatggct
      841 gttacatcgc cggaaaatgt aagcgttacc caagaatatg atgaagagaa agatattgaa
      901 ttatacacag ggaaagtgga acagttggtt catttgagag ctggtgaatg cctcatcact
      961 tttccagaag atttacatca acccaaggtt cgtataaatg atgaacctgt gaaaaaagtt
     1021 gtctttaaag ttgcgatttc ttaatgtaga aagagaagaa cgatgaaaaa aatgagaaag
     1081 tttttatgtc tagctggaat tgcgctagcg gctgttgcct tggtagcttg ttcaggaaaa
     1141 aaagaagcta caactagtac tgaaccacca acagaattat ctggtgagat tacaatgtgg
     1201 cactccttta ctcaaggacc ccgtttagaa agtattcaaa aatcagcaga tgctttcatg
     1261 caaaagcatc caaaaacgaa aatcaagatt gaaacatttt cttggaatga cttctatact
     1321 aaatggacta caggtttagc aaatggaaat gtgccagata tcagtacagc tcttcctaac
     1381 caagtaatgg aaatggtcaa ctcagatgct ttggttccgc taaatgattc tatcaagcgt
     1441 attggacaag ataaatttaa cgaaactgcc ttaaatgaag caaaaatcgg agatgattac
     1501 tactctgttc ctctttattc acatgcacaa gtcatgtggg ttagaacaga tttgttaaaa
     1561 gaacataata ttgaggttcc taaaacttgg gatcaactct atgaagcttc taaaaaattg
     1621 aaagaagctg gagtttatgg cttgtctgtt ccgtttggaa caaatgactt aatggcaaca
     1681 cgtttcttga acttctacgt acgtagtggt ggaggaagcc tcttaacaaa agatcttaaa
     1741 gcagacttga caagccaact tgctcaagat ggtattaaat actgggttaa attgtataaa
     1801 gaaatctcac ctcaagattc tttgaatttt aatgtccttc aacaagctac cttgttctat
     1861 caaggaaaaa cagcatttga ctttaactct ggcttccata tcggaggaat taatgccaac
     1921 agtcctcaat tgattgattc gattgatgct tatcctattc caaaaatcaa agagtctgat
     1981 aaagaccaag gaattgaaac ctcaaacatt ccaatggttg tttggaaaaa ttcaaaacat
     2041 ccagaagttg ctaaagcatt cttagaagca ctttataatg aagaagacta cgttaaattc
     2101 cttgattcaa ctccagtagg tatgttgcca actattaagg ggattagcga ttctgcagcc
     2161 tataaagaaa atgaaactcg taagaagttt aaacatgctg aagaagtaat tactgaagct
     2221 gttaaaaaag gtactgctat tggttatgaa aatggaccaa gtgtacaagc tggtatgttg
     2281 actaaccaac acattattga acaaatgttc caagatatca ttacaaatgg aacagatcct
     2341 atgaaagcag caaaagaagc agaaaaacaa ttaaacgatt tatttgaggc tgttcagtag
     2401 atgtaaaaga ctagaaaata ggtgggctag tgatctgaaa agctctagcc caattttgta
     2461 aaagaaggga gaaggagaat ggttaaagaa cgtaatttaa ctcgctggat atttgttttg
     2521 ccagctatga ttatcgtagg attactcttt gtttatccgt ttttctcgag tattttttat
     2581 agctttacca ataagcattt gattatgcct aattataaat ttgttggttt ggctaactat
     2641 aaagctgtgc tatcagatcc caacttcttt aatgcgttct ttaattcaat taagtggacc
     2701 gttttctcat tagttggtca agttttagta gggtttgtgt tggctttagc tcttcacaga
     2761 gtacgccact tcaagaaatt atataggacc ttattgattg ttccttgggc atttcctacc
     2821 atcgttattg ccttctcttg gcagtggatt ctaaacgggg tttatggcta cttacctaat
     2881 ctaatcgtaa aattaggttt aatggaacat acacctgcat ttttgacaga tagtacatgg
     2941 gcattcctat gtttggtgtt tatcaacatt tggtttggag caccaatgat tatggttaat
     3001 gtgctttcag ctttgcaaac agtaccagaa gaacaatttg aggctgctaa gatagatggt
     3061 gcttcaagtt ggcaggtgtt caagtttatc gtctttccac atattaaagt ggttgtagga
     3121 cttctagttg ttttgagaac tgtatggatc tttaataact ttgacattat ctacctcatt
     3181 actggtggtg gaccagccaa tgctacaacg acgcttccaa tttttgctta caacctgggt
     3241 tggggaacta aattgttggg tcgtgcttca gcagttacag tattgctctt tatcttcttg
     3301 gtggcgattt gctttatcta ctttgctatc atcagtaagt gggaaaagga gggtagaaaa
     3361 taatgaagaa gaaatccggt atttatttag atattctctc acatgtactt ttagttggtg
     3421 cgaccatcgt tgcagttttc ccattggtat ggattatcat atcttctgtc aaagggaaag
     3481 gggaattaac tcagtatcca acacgatttt ggcctgaaca gtttacatta gattatttca
     3541 ctcatgttat caacgatttg cacttcattg ataacattcg aaacagttta atcattgcct
     3601 tggctacaac ccttattgcg attattattt ctgctatggc agcctatggt attgttcgat
     3661 tctttcctaa attgggagca atcatgtcga gactactcgt cattacctat attttcccac
     3721 caattttgtt agcaattccc tattcaattg ccattgctaa agttgggtta acaaatagtt
     3781 tatttggctt gatgatggtt tatctatctt ttagtgttcc atatgcagtt tggctcttag
     3841 ttggattttt ccaaacagtt ccaattggaa ttgaagaagc ggctagaatt gatggtgcaa
     3901 ataaatttgt tacgttttat aaagttgtgc taccgattgt agcaccaggt attgtagcaa
     3961 cagctattta tacatttatc aatgcttgga atgaattcct gtatgccttg attttgatta
     4021 acaatacagg aaagatgaca gtagcagtag cccttcgttc acttaatggt tcagaaatac
     4081 tagactgggg agatatgatg gcagcgtctg ttattgtagt tcttccatca attattttct
     4141 tctctatcat ccaaaataag attgcaagtg gattatcaga aggatctgtg aagtagacga
     4201 aagaaggaaa aaaaatgaat aaaagaggtc tttattcaaa actaggaatt tctgttgtag
     4261 gcattagtct tttaatggga gttcccactt tgattcatgc gaatgaatta aactatggtc
     4321 aactgtccat atctcctatt tttcaaggag gttcatatca actgaacaat aagagtatag
     4381 atatcagctc tttgttatta gataaattgt ctggagagag tcagacagta gtaatgaaat
     4441 ttaaagcaga tgaaccaaac tctcttcaag ctttgtttgg cctatctaat agtaaagcag
     4501 gctttaaaaa taattacttt tcaattttca tgagagattc tggtgagata ggtgtagaaa
     4561 taagagacgc ccaaaaggga ataaattatt tattttctag accagcttca ttatggggaa
     4621 agcataaagg acaggcagtt gaaaatacac tagtatttgt atctgattct aaagataaaa
     4681 catacacaat gtatgttaat ggaatagaag tgttctctga aacagttgat acatttttgc
     4741 caatttcaaa tataaatggt atagataagg caacactagg agctgttaat cgtgaaggta
     4801 aggaacatta cctcgcaaaa ggaagtattg atgaaatcag tctatttaac aaagcaatta
     4861 gtgatcagga agtttcaaat attcccttgt caaatccatt tcagttaatt ttccaatcag
     4921 gagattctac tcaagctaac tattttagaa taccgacact atatacatta agtagtggaa
     4981 gagttctatc aagtattgat gcacgttatg gtgggactca tgattctaaa agtaagatta
     5041 atattgccac ttcttatagt gatgataatg ggaaaacgtg gagtgagcca atttttgcta
     5101 tgaagtttaa tgactatgag gagcagttag tttactggcc acgagataat aaattaaaga
     5161 atagtcaaat tagtggaagt gcttcattca tagattcatc cattgttgaa gataaaaaat
     5221 ctgggaaaac gatattacta gctgatgtta tgcctgcggg tattggaaat aataatgcaa
     5281 ataaagccga ctcaggtttt aaagaaataa atggtcatta ttatttaaaa ctaaagaaga
     5341 atggagataa cgatttccgt tatacagtta gagaaaatgg tgtcgtttat gatgaaacaa
     5401 ctaataaacc tacaaattat actataaatg ataagtatga agttttggag ggaggaaagt
     5461 ctttaacagt cgaacaatat tcggttgatt ttgatagtgg ctctttaaga gaaaaacata
     5521 atggaaaaca ggttcctatg aatgttttct acaaagattc gttatttaaa gtgactccta
     5581 ctaattatat agcaatgaca actagtcaga atagaggaga gagttgggaa caatttaagt
     5641 tgttgcctcc gttcttagga gaaaaacata atggaactta cttgtgtcct ggacaaggtt
     5701 tagcattaaa atcaagtaac agattgattt ttgcaacata tactagtgga gaactaacct
     5761 atctcatttc tgatgatagt ggtcaaacat ggaagaaatc ctcagcttca attccgttta
     5821 aaaatgcaac agcagaagca caaatggttg aactgagaga tggtgtgatt agaacattct
     5881 ttagaaccac tacaggtaag atagcttata tgactagtag agattctgga gaaacatggt
     5941 cggaagtttc gtatattgat ggaatccaac aaacttcata tggcacacaa gtatctgcaa
     6001 ttaaatactc tcaattaatt gatggaaaag aagcagtcat tttgagtaca ccaaattcta
     6061 gaagtggccg taagggaggt caattagttg tcggtttagt caataaagaa gatgatagta
     6121 ttgattggaa ataccactat gatattgatt tgccttcgta tggttatgcc tattctgcga
     6181 ttacagaatt gccaaatcat cacataggtg tactgtttga aaaatatgat tcgtggtcga
     6241 gaaatgaatt gcatttaagc aatgtagttc agtatataga tttggaaatt aatgatttaa
     6301 caaaataaag gagaaaaaca tggttaaata cggtgttgtt ggagcagggt attttggagc
     6361 tgaattggct cgctacatgc aaaaaaatga tggagcagag attactcttc tctatgatcc
     6421 agataatgca gaggcgattg cagaagaatt gggagcaaaa gtagcaagtt ccttagatga
     6481 gttggtttct agcgatgaag tagactgtgt tatcgtcgca actccaaata atcttcataa
     6541 ggaaccggtt attaaggctg cacagcatgg taaaaatgtt ttctgtgaaa aaccaattgc
     6601 gctttcttat caagattgtc gcgagatggt agatgtgtgt aaagaaaaca atgtaacctt
     6661 tatggcagga catattatga atttctttaa tggtgttcat catgcaaaag aactcattaa
     6721 tcaaggagtt atcggagacg ttctatattg tcatacagct cgtaatggtt gggaagaaca
     6781 acaaccgtca gtatcatgga aaaaaattcg tgaaaaatca ggtggtcact tgtatcacca
     6841 catccatgaa ttggattgcg ttcaattcct tatggggggc atgcctgaaa ctgtaaccat
     6901 gacaggtgga aatgtggccc atgaaggtga acatttcggt gatgaagatg atatgatttt
     6961 tgtcaatatg gaattttcta ataagcgttt tgctttgtta gaatggggtt cagcttatcg
     7021 ttggggtgaa cattatgtct taatccaagg aagcaaaggt gccatccgct tagacttatt
     7081 caactgtaaa ggaactctta agctagatgg gcaagaaagc tatttcttga ttcacgaatc
     7141 gcaagaagaa gatgatgatc ggactcgtat ctatcatagt acagagatgg atggagcaat
     7201 tgcttatggt aaaccaggta aacgtactcc attatggcta tcatctgtca ttgataaaga
     7261 aatgcgctat ctgcatgaga ttatggaagg agctccagta tcagaagaat ttgcaaaact
     7321 tttgacaggt gaagctgccc tagaagcaat tgctactgca gatgcttgta cccagtctat
     7381 gtttgaagat cgcaaagtaa gattgtcaga aattgtaaaa taaattttgg tattctccta
     7441 tctataggtc gacttgctcc tctgaaagta cttttagagg agctgtttga ctttgctagt
     7501 ttttgaaact gaaatctatt atactacaaa ctattgaaag cgttttaatt ttaaggtata
     7561 ataatctcat agaaataaag aaaaggagga aagaggatgc cacagattag caaagaagcc
     7621 ttgattgagc aaatcaaaga tggaatcatc gtttcttgtc aggctcttcc tcatgaaccg
     7681 ctttatacag aagtgggagg ggtgattccc ttgctggtca aagcggctga gcaaggtgga
     7741 gcagtcggta tccgagcaaa cagtgttcgc gatatcaagg aaattaagga agtcactaaa
     7801 cttccaatca ttgggattat caaacgtgat tatccacctc aggaaccctt tatcacggct
     7861 actatgaaag aagttgatga attggcagaa ctggacatcg aggtgattgc tctggattgt
     7921 accaagcgtg aacgctacga tggtttggaa attcaagagt tcattcgtca ggttaaggag
     7981 aaatatccta atcagctttt gatggctgat actagtatct tcgaagaagg gctagcagct
     8041 gtagaagcag gaattgactt tgtcggaaca accttatcag gctacacatc ctacagtcca
     8101 aaagtagacg gtccagattt tgaattgatt aagaaactct gtgatgccgg tgtagatgtc
     8161 attgcagaag gaaaaattca tacaccagaa caagccaaac aaatccttga atatggagtg
     8221 cgaggcatcg ttgttggtgg cgccattact agaccaaaag agattacaga acgcttcgtt
     8281 gctagtctta aataagatgt gagggggagt tttatgttta aagttttaca aaaagttgga
     8341 aaagctttta tgttacctat agctatactt cctgcagcag gtctactttt ggggattggt
     8401 ggtgcacttt caaacccaac cacgatagca acttatccaa tactagacaa tagtattttt
     8461 caatcaatat tccaagtaat gagctctgca ggagaggttg tattcagtaa tttgtcacta
     8521 cttctctgtg tgggattatg tattggctta gcgaaacgag ataaaggaac cgctgcgtta
     8581 gcaggagtaa ctggttactt agttatgact gcaacgatca aagctttagt aaaacttttt
     8641 atggcagaag gatctgcaat tgatactgga gttattggag cattagttgt cggaatagtt
     8701 gccgtatatt tgcacaaccg atataacaat attcaattac cttccgcttt aggattcttt
     8761 ggaggttcac gcttcgttcc tattgttaca tcgttctctt ctatcttgat tggctttgtc
     8821 ttctttgtta tttggccacc tttccaacaa cttcttgttt ctacaggtgg atatatttct
     8881 caggcgggtc caattggaac ttttctatat ggatttttaa tgagactttc tggagcagta
     8941 ggcttacatc atataattta ccctatgttt tggtatactg aacttggtgg tgttgaaact
     9001 gttgcaggac aaacagtggt tggagctcaa aaaatatttt ttgctcaatt agccgatctg
     9061 gcccattctg gattatttac agaaggaaca aggttttttg caggtcgttt ctcaacaatg
     9121 atgttcggtt taccggctgc ctgtttagcg atgtaccata gtgttcctaa aaatcgtcgt
     9181 aaaaaatacg cgggtttgtt tttgggagtt gctttaacat cttttattac cggtattaca
     9241 gaaccaattg aatttatgtt tctattcgtc agtccggttc tatatgttgt tcacgcattc
     9301 cttgatggtg ttagcttctt tattgcagac gtcttaaata tttcaatagg aaacacattt
     9361 tcaggaggtg taatcgattt cacattattt ggaattttgc aggggaacgc taagacgaat
     9421 tgggttcttc agattccatt tggacttatt tggagtgttt tgtattatat tatttttaga
     9481 tggttcatta ctcaattcaa cgttctaacg ccagggcgag gagaagaagt agattctaaa
     9541 gaaatttctg aatccgcaga ttcaacttca aatactgcag attatttaaa acaggatagc
     9601 ctacaaatta tcagatcctt gggtggatca aataatatag aagatgtaga tgcttgtgtg
     9661 acacgtttac gtgtagctgt aaaagaagtt aatcaagttg ataaagcact tttaaaacaa
     9721 attggtgcag ttgatgtctt agaagtgaag ggtggcattc aagcaatcta tggagcaaaa
     9781 gcaatcttat ataaaaatag tattaatgaa attttaggtg tagatgatta agtacttact
     9841 gacttaataa aaaacagagg agagtgatgg atgagtagga tgaaatgaaa tcgcatacaa
     9901 gaaataaaga actcattatc caagttggat acgcttatta cataggagaa tacaaatgaa
     9961 atttagaaaa ttagcttgta cagtacttgc gggtgctgcg gttcttggtc ttgctgcttg
    10021 tggcaattct ggcggaagta aagatgctgc caaatcaggt ggtgacggtg ccaaaacaga
    10081 aatcacttgg tgggcattcc cagtatttac ccaagaaaaa actggtgacg gtgttggaac
    10141 ttatgaaaaa tcaatcatcg aagcgtttga aaaagcaaac ccagatataa aagtgaaatt
    10201 ggaaaccatc gacttcaagt caggtcctga aaaaatcaca acagccatcg aagcaggaac
    10261 agctccagac gtactctttg atgcaccagg acgtatcatc caatacggta aaaacggtaa
    10321 attggctgag ttgaacgacc tcttcacaga tgaatttgtt aaagatgtca acaatgaaaa
    10381 catcgtacaa gcaagtaaag ctggagacaa ggcttatatg tatccgatta gttctgcccc
    10441 attctacatg gcaatgaaca agaaaatgtt agaagatgct ggagtagcaa accttgtaaa
    10501 agaaggttgg acaactgatg attttgaaaa agtattgaaa gcacttaaag acaagggtta
    10561 cacaccaggt tcattgttca gttctggtca agggggagac caaggaacac gtgcctttat
    10621 ctctaacctt tatagcggtt ctgtaacaga tgaaaaagtt agcaaatata caactgatga
    10681 tcctaaattc gtcaaaggtc ttgaaaaagc aactagctgg attaaagaca atttgatcaa
    10741 taatggttca caatttgacg gtggggctga tatccaaaac tttgccaacg gtcaaacatc
    10801 ttacacaatc ctttgggcac cagctcaaaa tggtatccaa gctaaacttt tagaagcaag
    10861 taaggtagaa gtggtagaag taccattccc atcagacgaa ggtaagccag ctcttgaata
    10921 ccttgtaaac gggtttgcag tattcaacaa taaagacgac aagaaagtcg ctgcatctaa
    10981 gaaattcatc cagtttatcg cagatgacaa ggagtgggga cctaaagacg tagttcgtac
    11041 aggtgctttc ccagtccgta cttcatttgg aaaactttat gaagacaaac gcatggaaac
    11101 aatcagcggc tggactcaat actactcacc atactacaac actattgatg gatttgctga
    11161 aatgagaaca ctttggttcc caatgttgca atctgtatca aatggtgacg aaaaaccagc
    11221 agatgctttg aaagccttca ctgaaaaagc gaacgaaaca atcaaaaaag ctatgaaaca
    11281 atagtcctta gttattctat aaaaagtagt tttttaaaga acctaagagt gtataccccc
    11341 ttttccctct acacagatag tgtaagaaaa gggggctttt gtttaaaatg taagaaactg
    11401 tcacgaaatt aaaatgaagt tcttacataa gcgaatcata aaaaatttca ttttgatttt
    11461 aaaacagttc aagaaagtca aaaaattatt ctatttgaaa gagaggtgcc gactgtgaaa
    11521 gtcaataaaa tccgtatgcg ggaaacagtg atttcctacg ctttcctagc accagtatta
    11581 ttcttctttg tcatctttgt gttggctccg atggtgatgg gcttcattac aagtttcttt
    11641 aactactcaa tgactaaatt tgagtttgta ggcttggata actatatccg tatgtttaaa
    11701 gatcctgtct ttacaaaatc tctgattaac acagttattt tggttattgg atctgtacca
    11761 gttgttgttc tattctcact ctttgtagca tctcagacct atcatcaaaa tgtcattgcc
    11821 agatccttct accgtttcgt cttcttcctt cctgttgtaa cgggtagtgt tgccgtgaca
    11881 gttgtttgga aatggattta tgacccacta tcagggattc taaactttgt ccttaagtca
    11941 agccacatca tcagccaaaa catttcttgg ttgggagata aaaactgggc attgatggcg
    12001 attatgatta ttctcttgac cacttcagtt ggtcagccca tcatccttta tatcgctgcc
    12061 atggggaata tcgacaattc actggttgaa gcggcgcgtg ttgatggtgc aactgagttt
    12121 caagtttttt ggaagattaa atggccaagc cttcttccaa caactcttta tattgcaatc
    12181 atcacaacaa ttaactcatt ccagtgtttc gccttgattc agcttttgac atctggtggt
    12241 ccaaactact caacaagtac cttgatgtac tacctttacg aaaaagcctt ccaattgaca
    12301 gaatacggct atgccaacac aattggtgtc ttcttggcag tcatgattgc tatcgtaagc
    12361 tttgttcaat ttaaagtact tggaaacgac gtagaatact aaagaaagga gacagctatg
    12421 caatctacag aaaaaaaacc attaacagcc tttactgtta tttcaacaat cattttgctc
    12481 ttgttgactg tgctgttcat ctttccattc tactggattt tgacaggggc attcaaatca
    12541 caacctgata caattgttat tcctcctcag tggttcccta aaatgccaac catggaaaac
    12601 ttccaacaac tcatggtgca gaaccctgcc ttgcaatgga tgtggaactc agtatttatc
    12661 tcattggtaa ccatgttctt agtttgtgca acctcatctc tagcaggtta tgtattggct
    12721 aaaaaacgtt tctatggtca acgcattcta tttgctatct ttatcgctgc tatggcgctt
    12781 ccaaaacaag ttgtccttgt accattggta cgtatcgtca acttcatggg aatccacgat
    12841 actctctggg cagttatctt gcctttgatt ggatggccat tcggtgtctt cctcatgaaa
    12901 caatttagtg aaaatattcc tacagagttg cttgaatcag ctaaaatcga cggttgtggt
    12961 gagattcgta ccttctggag tgtagccttc ccgattgtga aaccagggtt tgcagccctt
    13021 gcaatcttta ccttcatcaa tacttggaat gactacttca tgcaattggt aatgttgact
    13081 tcacgtaaca atttgaccat ctcacttggg gttgcgacca tgcaggctga aatggcaacc
    13141 aactatggtt tgattatggc aggagctgcc cttgctgctg ttccaatcgt cacagtcttc
    13201 cttgtcttcc aaaaatcctt tacacagggt attactatgg gagcggtcaa aggataatac
    13261 tctgcgaaaa tcgaatgcaa actacgtcag cttcaccttg ccatacttaa gtattgcttg
    13321 cggttagctt cctagtttgt tcttcaattt tcattgagta taggaaaatc aatctatcaa
    13381 gatacagaag tatattttat agatttagag aatatataag ttataagtgt ctacaaaatg
    13441 gagggtatgc agttacttta tgaagttttg tcagacactt ataaacttaa gaatggtttt
    13501 agttaactat cagaaacgaa ggaaagagta tgatttttga cgatttgaaa aacatcacct
    13561 tttacaaagg gattcatccc aatttagaca aggctatcga ctacctctac caacatcgta
    13621 aagattcatt cgaattagga aagtatgaga ttgatggaga taaagtcttt ctagttgttc
    13681 aggaaaatgt cctcaatcaa gttgagaata atcaatttga acaccataag aactatgcag
    13741 atttgcattt gctgatagaa gggcatgaat attcgagcta cggttcacgt atcaaagacg
    13801 aggcagtagc attcgacgaa gcgagtgaca ttggctttgt tcattgtcat gaacactacc
    13861 cgctcttgtt gggttatcac aattttgcga ttttcttccc aggtgagcca catcagccaa
    13921 atggttatgc aggcatggaa gaaaaggttc gaaaatatct ctttaaaatc ttgattgatt
    13981 aaaaatagga tgaattgttt ttttgtaaag ctttgataat actctaccat gaaattgatc
    14041 tttgtgaggt agagaaatga gaataaaata tttaaaaatt ggtatcttct aagtatgctg
    14101 caagagctag tttcttagat ggacagggga ttacagttga tgagatgtcc tggataatta
    14161 ggggcattgt gaatggattg attggtagat acataaaatt aggtacttat gcagctaagt
    14221 atggtattag tatggcgcgc tcgatcttaa gtagggcagc tgcaactgcg gcagcaagag
    14281 taagattatt gactaagatt tttggatgga ttttacgaat agctgtgctc gcagctgatg
    14341 tatatggtaa ttttgccaac aatattgctg cagcttggga tgcacatgat aaaatcccta
    14401 acaatggtcg tataaacttt taaaatgcga gaatgaaagc actttgtatt tttttattgt
    14461 atatgttagc ttggacagtg cttgcaatga taatccgtgg agggctagat ggatttgatg
    14521 aacacacttg gcgtaatatt ttagctagtg cgttgtcctc gctatacata cattatatat
    14581 ccatagataa aaatagaaaa aagtccaaaa gaaaaaagaa aaaatagatt tgttcatggt
    14641 agggacttat gaaagcttta ctgacaaaaa agaaaacagt ttacaaagaa aaatgatgga
    14701 ggagcaaaca tggcacaaaa aggagtaagc cttatcaagg cagcatttga tacagataac
    14761 tttctcatgc gttttagtga gaaggtcttg gacatcgtga cagccaatct tctttttgtc
    14821 gtctcttgtt tgcccatcgt gacgattgga gtggctaaaa tcagcctcta cgagaccatg
    14881 ttcgaagtta agaagagcag acgggtgcct gtttttaaaa tctatctaag atctttcaag
    14941 caaaatctga aactaggtct tcagttaggt ctgcttgagt tgggcattgt ttcattaagc
    15001 ctcctagatc tttatctctt ttggggtcaa acagctctgc cctttcaatt gctgaaagct
    15061 atttgtctag gcattctgat tttccttacg attgtgatgt tggctagcta tccaatcgcg
    15121 gcacgttatg atttaacttg gaaagaaatt cttcaaaaag gattgatgtt ggctagtttt
    15181 aactttcctt ggttcttcct catgttagcc attcttgtcc tcattgtgat ggttctttat
    15241 ctgtctgcct tcagtctact cttaggtggc tcagtcttcc tgctttttgg gtttggacta
    15301 ttggtcttta tccagactgg attgatggag aaaattttcg caaaatacca ataggagcct
    15361 tatttctgaa actactttca aaggctccaa acgctattct ataagcgaga aactaaaatc
    15421 taagtgtcta taagatattg aaagcctttt cggtaaagtg tatactaaag aagtaaagaa
    15481 aaatctgctt tagcagaaaa taaaaataat aggagaaaat ctatgtcaga tttgaaaaaa
    15541 tacgaaggtg tcattccagc cttctacgca tgttatgatg agcaaggaga agtaagtcca
    15601 gagcgtacgc gtgccttggt tcaatacttc attgataaag gtgttcaagg tctttatgtc
    15661 aatggttctt ctggtgaatg tatctaccaa agcgttgaag atcgcaagtt gattttggaa
    15721 gaagtcatgg cggtagccaa aggtaaattg accattattg cccatgttgc ttgcaataat
    15781 actaaagata gtatggaact tgctcgccat gctgaaagct tgggagtaga tgctattgca
    15841 acgattccac caatttactt ccgcttgcca gaatactcag ttgccaaata ctggaacgat
    15901 attagttctg cagctccaaa cacagactac gtgatttaca acattcctca attggcaggg
    15961 gttgctttga ctccaagcct ttacacagaa atgttgaaaa atcctcgtgt tatcggtgtt
    16021 aagaactctt ctatgccagt tcaagatatc caaacctttg tcagccttgg cggggaagac
    16081 catattgtct ttaacggtcc agatgaacag ttcctaggtg gccgcctcat gggtgctaag
    16141 gctggtatcg gtggtactta tggtgctatg ccagaactct tcttgaaact caatcagttg
    16201 attgcggata aggacctaga aacagcgcgt gaattgcagt atgctatcaa cgcaatcatt
    16261 ggtaaactca cttctgctca tggaaatatg tacggtgtca tcaaagaagt cttgaaaatc
    16321 aatgaaggct tgaatattgg atctgttcgt tcaccattga caccagtaac tgaagaagat
    16381 cgtccagttg tagaagcggc tgcagccttg attcgtgaaa ccaaggagcg cttcctctaa
    16441 tctaaaagga ggtatttatg acatactacg ttgcaattga tatcggtgga actaacatca
    16501 agtatggttt ggttgatcaa gaggggcaac ttcttgaatc gcatgaaatg ccaactgagg
    16561 cgcataaggg tggacctcat atcttacaaa agaccaaaga tatcgtagct agttatttag
    16621 aaaaaggccc agtagcaggt gttgccatat cttctgctgg gatggtggat ccggataagg
    16681 gtgagatttt ctatgctggg ccgcaaatcc ctaactacgc aggcacccag ttcaaaaagg
    16741 aaatcgaaga aagctttact attccttgtg agattgaaaa tgatgtcaac tgtgcaggtc
    16801 ttgctgaggc agtatctggt tcaggcaagg gagcaagtgt gacactttgc ttgaccattg
    16861 gaacaggtat cggtggttgc ttgattatgg ataggaaagt cttccatggt tttagtaatt
    16921 cagcctgtga agtcgggtat atgcatatgc aggatggagc ttttcaagac ttggcttcta
    16981 caacagcttt agtgaaatat gtagctgaag cccatggaga agatgttgat cagtggaatg
    17041 gccgacgtat ctttaaggaa gctactgaag gaaacaaaat ctgcatggaa ggtattgacc
    17101 gtatggttga ctatctagga aaaggtctgg caaatatttg ctacgttgcc aatccagaag
    17161 tggttattct tggtggtggt atcatggggc aagaggctat cctcaaacct aagatccgca
    17221 cagccttgaa agaggctttg gtaccaagtt tagcagaaaa aacacgatta gaatttgccc
    17281 atcaccaaaa tacagcaggg atgttgggtg catattatca ttttaagaca aaacaatcct
    17341 agtttggctc agccaaacta ggattttctt acacgttttt gtctacgata gccgttgagt
    17401 tttttatttt cccagtagct attaaagatt ttttccttgc tttcgcgatt gatttccaaa
    17461 aagtaggcat aaatcaaatc gataaagaag agcataggaa gttgagcgga tattcgttgg
    17521 atataggagg gttggctgtg ggtggctaca agaacagtct ctgtataggt ctggctatct
    17581 ttattgggaa cacttgtaaa gagtacagtc tttgccccca tctccttggc atctaataga
    17641 ctatctaaaa tagaaggagt tgagcctgaa agtgagaagc ccagtactag acaattttca
    17701 tccatgatgc tggttgtcca ggcaaagccg tcttggtctg tcaaagcttc gcagaccaca
    17761 cctagtcgca taaaacgtaa tttcatttca cgggcgacga ggccagaact ccctgttccg
    17821 aagaagtaga tacgctcagc atcttcgatt agctgggcaa ttcgttctag ttggatttcg
    17881 tcaatcaagt cttgtgtttg ttccctcatg ttgctataac ttctgaggac tcgtttggtc
    17941 agtggactgt gcttggagac ttggttggct tgattttctg cctgatgttg gtattggaaa
    18001 ataaattctc ggtagccagt aaagccacac tttttagcaa agcgggtcaa agcagcttga
    18061 gaaatatgta atttttgggt gacttgttga gaagataaat catctgtaat cgtttcagct
    18121 tgcaaaaaat agcgagcgat ttcttgttct aggtctgtca tttcttcaaa atgtgaatca
    18181 atgatagttg cgatatctgg tttgtccata gggaaagctc ctttacatga gtcatactgg
    18241 aagactagat cagggaatag tcacacttca ttataacaca taatataagg atagataaat
    18301 aaaaacgcat ctctgtttta aaaacgaaaa aatcgaaaaa gcttctttct tttccataat
    18361 tttctactca aattgtggta caattaagag taagatttta agttagaaat gagactgatt
    18421 tgtatgagaa aatttaacag ccattcgatt ccgattcggc ttaatttatt gttttcaatc
    18481 gtcattttac tctttatgac cattattggt cgtttgttgt atatgcaggt tttgaacaag
    18541 gatttttacg aaaaaaagct agcctcagct agtcagacca agattacaag cagttcagcc
    18601 cgtggggaaa tttatgatgc tagtggaaaa cctttggtag aaaatacgtt aaagcaggtt
    18661 gtttccttta cgcgtagcaa taaaatgacg gctacagact taaaagaaac agctaaaaag
    18721 ttactgactt atgtgagcat cagttctcca aatttgacag aacgccagct ggcggattac
    18781 tatttggctg atcctgaaat ctataaaaaa acagtggaag ctctcccaag cgagaaacgc
    18841 ttggattcag atggcaatcg tctatccgaa tcagaactgt ataacaatgc ggtcgatagt
    18901 gtacaaacga gtcaactaaa ctatacagag gatgaaaaga aagaaatcta tctttttagt
    18961 cagttaaatg ctgttggaaa ctttgcgaca ggaaccattg cgacagatcc tctaaatgat
    19021 tctcaggtgg ctgttattgc ctctatttca aaggagatgc ctggcattag tatttctact
    19081 tcttgggata gaaaggtttt ggaaacttcc ctttcttcta tagttgggag tgtatccagt
    19141 gaaaaagctg gtctcccagc ggaagaagca gaagcctatc ttaaaaaagg ctattctcta
    19201 aatgatcgtg taggaacctc ctatttggaa aagcaatatg aagagacctt acaaggaaaa
    19261 cgctcggtaa aagaaatcca tctggataaa tatggcaata tggaaagcgt ggatacaatt
    19321 gaggaaggta gtaagggaaa caatatcaaa ctgaccattg atttggcttt ccaagatagc
    19381 gtggatgctt tactgaaaag ttatttcaat tctgagctag aaaatggtgg agccaagtat
    19441 tctgaaggtg tctatgcagt cgcccttaac ccaaaaacag gtgcggtttt gtctatgtca
    19501 gggattaaac atgacttgaa aacgggagag ttgacgcctg attccttggg aacggtaacc
    19561 aatgtctttg ttccaggttc ggttgtcaag gcggcgacca tcagctcagg ttgggaaaat
    19621 ggagtcttgt caggaaacca gaccttgaca gaccagtcca ttgtcttcca aggttcagct
    19681 cccatcaatt cttggtatac tcaggcttac ggttcattcc ctatcacagc ggtccaagct
    19741 ctggagtatt catcaaatac ctatatggtc caaacagcct taggtcttat ggggcaaacc
    19801 tatcaaccca atatgtttgt cggcaccagc aatctagagt ctgctatgga gaaactgcgt
    19861 tcaacctttg gcgaatatgg cttgggtact gcgacaggaa ttgacctacc agatgaatct
    19921 actggatttg ttcccaaaga gtatagcttt gctaattaca ttactaatgc ctttgggcag
    19981 tttgataact atacgccgat gcagttggct cagtatgtag caactattgc aaataatggt
    20041 gttcgtgtgg ctcctcgtat tgttgaaggc atttatggta ataatgataa gggaggactg
    20101 ggtgacttga ttcagcaact gcaaccgaca gagatgaata aggtcaatat atccgactcc
    20161 gatatgagca tcttgcacca aggtttttat caggttgccc atggtactag tggattgaca
    20221 actggacgtg ccttttcaaa tggtgccttg gtatccatta gcggaaaaac aggtacagcc
    20281 gaaagctatg tggcagatgg tcagcaagca accaatacca atgcggtggc ctatgcccca
    20341 tctgataatc cccaaatcgc tgtcgcagtg gtctttcctc ataataccaa tctaacaaat
    20401 ggtgtaggac cttccattgc gcgtgacatt atcaatctgt atcaaaaata ccatccaatg
    20461 aactagaaag gaaattatgc tttatccaac acctattgcc aagttgattg acagttattc
    20521 taagttacca ggtatcggga ttaagacggc tacgcgtctg gccttttata cgattgggat
    20581 gtctgctgat gatgtcaatg aatttgcaaa aaatctcctt tctgctaaga gagaattgac
    20641 atattgttct atttgtggac gtttgacaga cgacgatcct tgttctatct gtactgattc
    20701 gactcgtgac cagacaacaa ttttagttct tgaggatagt agagatgtgg cagccatgga
    20761 aaatatccaa gaataccatg gactctatca tgtcctgcat ggcctcattt ctcctatgaa
    20821 tggtatcagt ccggacgata tcaatcttaa gagccttatg actcgtctta tggatagtga
    20881 ggtttcagaa gtgattgtgg cgactaatgc tacagcggat ggtgaagcga cctccatgta
    20941 tctttcacgt ttgctcaagc cggctggtat caaggttacg cgtctagcac gaggtctcgc
    21001 tgtgggagcg gacattgagt atgcggacga agtgacactc ttacgagcga ttgaaaatcg
    21061 gacagagttg taagtgtagg caaatttacg aactccattc atttataaaa aatcaaagag
    21121 gctgaaaatc gttcctatcg gcctcttttt gtatagtgtg atgagtagga tcaggttcaa
    21181 gttttaaaaa accaagcaaa tatgatatac taaagagcga gtattctagt agaattagga
    21241 caaataatat gaaacaaacg attattcttt tatatggtgg acggagtgcg gaacgcgaag
    21301 tctctgtcct ttcagctgag agtgtcatgc gtgcggtcaa ttacgaccgt ttcatagtca
    21361 agactttctt tatcagtcag tcaggtgact ctatcaaaac gcaggaattt agtcatgctc
    21421 cggggcaaga agaccgtctc atgaccaatg aaaccattga ttgggataag aaagttgcac
    21481 caagtgctat ctacgaagaa ggtgcagtgg tctttccagt ccttcacggg ccaatgggag
    21541 aagatggctc tgttcaagga ttcttggaag ttttgaaaat gccttacgtt ggttgcaaca
    21601 ttttgtcatc aagtcttgcc atggataaaa tcacgactaa gcgtgttctg gaatctgctg
    21661 gtattgccca agttccttat gtggctatcg ttgaaggcga tgatgtgact gctaaaatag
    21721 ctgaagtgga agaaaaattg gcttatccag tcttcactaa gccgtcaaac atggggtcta
    21781 gtgtcggtat ttctaagtct gaaaaccaag aagaactccg tcaagcctta aaacttgcct
    21841 tccgatatga cagccgtgtc ttggttgagc aaggagtgaa tgcccgtgaa attgaggttg
    21901 gcctcttggg taactacgat gtcaagagca cgctacctgg agaagttgtc aaggacgttg
    21961 ccttttatga ctacgatgcc aagtatattg ataacaaggt tactatggat attcctgcca
    22021 aaatcagtga tgatgtggtg gctgtcatgc gtcaaaatgc agaagcagcc ttccgtgcca
    22081 ttggtggcct tggtctatct cgttgcgatt tcttctatac agataaggga gagatttttc
    22141 tcaacgagct caataccatg ccaggtttca cccagtggtc tatgtaccca ctactttggg
    22201 aaaatatggg gatcagctac ccagaactaa tcgagcgttt ggttgacctt gccaaggaaa
    22261 gttttgacaa gcgcgaagcg catttgatat aaaatgaaag agagggtaga agccagaacc
    22321 atcactgcaa ggtgactaga gttctcggac ttcgcccctt tttaaaggag tagaaatgaa
    22381 attaacaatc tatgaagttg cccaagctgt tggagctaaa aatgatgtta gtctttttgc
    22441 ggacgcccag ttagaaaagg ctgagtttga cagtcgattg attgggactg gagatttatt
    22501 tgtgccactt aaaggtgcgc gtgatggcca tgactttatt gaaacagcct ttgaaaatgg
    22561 tgcagcagta accttgtctg agaaagaggt ctcaaatcat ccttacattc tagtagatga
    22621 tgttttgaca gcctttcaat ccttagcatc ctactatctt gaaaaaacga ctgttgatgt
    22681 ctttgctgtt acaggttcaa atggcaagac aacgactaag gatatgttgg cgcatttact
    22741 gtcaacaaga tacaagacct acaaaacaca aggcaattac aataatgaga ttggccttcc
    22801 ttacacagtt cttcatatgc ctgaaggaac agaaaagttg gttttggaga tgggacagga
    22861 tcacttggga gatattcatc tcttgtctga attggctcgt ccaaaaacag ccatcgtgac
    22921 cttggttgga gaagctcatt tggccttttt caaagatcgt tctgagattg ctaaaggaaa
    22981 aatgcaaatt gcagacggaa tggcttcagg ttccttgctt ttaacgccgg ctgaccctat
    23041 cgtagaggac tatttgccaa ctgataaaaa ggtggtccgt tttgggcaag gggcagagtt
    23101 ggaaatcaca gacttggttg agcgtaagga cagtctgacc tttaaggcta atttcttgga
    23161 acaagccctt gatttgccag tgactggtaa gtacaatgct accaatgcta tgattgcgtc
    23221 ctatgttgcc ctacaagaag gagtttcaga ggagcaaatt catcaggcct tccaaggtct
    23281 tgaattgacg cgtaatcgta ctgagtggaa gaaagcagcc aatggagcag atatcctgtc
    23341 agacgtatat aatgccaatc caactgctat gaagctgatt ttagagactt tctctgccat
    23401 tccagccaat gaaggtggca agaaaattgc agtgttggcg gatatgaagg agcttggtga
    23461 ccagtctatt caactccata accagataat tttgagcctt tctccagatg tgcttgatac
    23521 cgttattttc tatggagaag acattgctga attagcccaa cttgctagtc aaatgttccc
    23581 aatcggacac gtttattact tcaagaaaac agaagaccaa gaccaatttg aagacctagt
    23641 taagcaggtc aaagaaagcc ttggggctca tgaccaaatc ctgctcaaag gctctaactc
    23701 tatgaatcta gccaagttgg tagaaagttt agaaaatgaa gacaagtgat tttgtcaagt
    23761 atttgcaaag aatgattgcc attacagata ctggcttaac ctttacaaaa gatccgtttg
    23821 accgtgagcg ctacgaagac ttgcgagact ttttatctga aatgttgaat caagcatcag
    23881 accttgattc cgaagaagtg gcagaagtct tgaagccaac ttctgcttat gcgactccgt
    23941 taatggacgt ccgtgcttgg attgttgagg acgaaaagat ttgtctggtt aggggacaag
    24001 gagaggatag ttgggctttg ccaggtggct ttggtgaggt tggctattct ccaacagaaa
    24061 atattctcaa ggaaattgaa gaagaaaccg gttttaaagc caaagttgaa agactgctag
    24121 ctgtttttga taccaatcgt ttccaactac agagcaaaca gtatacaaag tttgtttttg
    24181 gatgtaagct tctcgatgga caattccaag aaaatcaaga aattgctgac cttcaatttt
    24241 ttgccattga ccaactgccg aacttatctg aaaaacgcat taccaaggag caaatagagc
    24301 ttctttggca ggtttatcaa ggtcataggg ggcaatatct tgactaagaa gatgattatc
    24361 gtatttctaa atccattttt gacaactagc atggtataat aatatgcagg aaaattttga
    24421 attatgagga agactagatg aatttatggg atattttctt tacgactcag gcaaccgagc
    24481 cgcccaaatt tgaccttttt tggtatgtta gcctatttac gctcttagcc ttaacctttt
    24541 atacagccca tcgctatcgt gaaaagaagg tttaccaacg atttttccaa atcttgcaga
    24601 ctgttcagtt aatccttctt tatggttggt actgggtcaa tcatatgcca ctgtcagaaa
    24661 gcctaccctt ttaccattgc cgtatggcta tgtttgtggt actcttgctt cctggtcaat
    24721 ccaaatataa acaatacttt gcattattgg gaacatttgg gacattagca gcctttgttt
    24781 atccagtgcc agatgcttac ccttttccac atatcaccat tctatccttt atctttggtc
    24841 atttagcact cttggggaac tctctagttt atctattgag acagtataat gcgcgattgc
    24901 tggatgtgaa gggaattttt ctcatgacct ttgccctaaa tgccttgatt tttgtggtca
    24961 atttggtgac aggtggcgat tacggatttt tgacaaaacc gccattggtt ggggctcacg
    25021 gtctagtagc taattattta cttgtttcaa ttgtgctggt agctactatc agtttgacta
    25081 agaaaatctt agaattcttt ttagctcaag aagcagaaaa aatgattgca aaggaagctt
    25141 aacacagagc tttctttttt gctcttagag agtttttaca agcagcttat aaaataagaa
    25201 tttctgaata gacaaactca aaaaatggct gggaaattta ggaaaaaagc aagcacgatt
    25261 aaattttttg tgttataata ttttgtgaat agctatgcct atgtttagct atggaataat
    25321 acgaagtgcg aaacttggaa gatagagagg aagcgatgta atggctagag aaggcttttt
    25381 tacaggtcta gatattggaa caagctctgt caaggtgctt gtggccgagc agagaaatgg
    25441 tgaattaaat gtaattggcg tgagtaatgc caaaagtaaa ggtgtaaagg atggaattat
    25501 tgttgatatt gatgcagcag caactgctat caagtcagcc atttcccaag cggaagaaaa
    25561 ggcaggcatt tcgattaaat cagtgaatgt cggcttgcct ggtaatcttt tgcaggtaga
    25621 accaactcag gggatgattc cagtaacatc tgatactaag gaaattacgg atcaagatgt
    25681 tgaaaatgtt gtcaaatcag ctttgacaaa gagtatgaca cctgaccgtg aagtcattac
    25741 ctttattcct gaagaattta ttgtggatgg tttccaaggg attcgtgacc cacgtggcat
    25801 gatgggggtt cgccttgaaa tgcgtggttt gctttataca ggacctcgta ctatcttgca
    25861 caatttgcgt aagacggttg agcgtgcagg tgttcaggtt gaaaatgtta tcatttcacc
    25921 actagcaatg gttcagtctg ttttgaacga aggggaacgt gaatttggtg ctacagtgat
    25981 tgatatgggg gcaggtcaaa cgactgtcgc tacaatccgt aatcaagaac tccagttcac
    26041 acatattctc caagaaggtg gagattatgt aactaaagat atctccaagg ttttgaaaac
    26101 ctctcgcaaa ttagcggaag gcttgaaact gaattacggg gaagcctatc cgcctcttgc
    26161 aagcaaagaa accttccaag tagaggttat tggagaagta gaagcagtcg aagtgacgga
    26221 agcctacttg tcagaaatta tttctgcacg aatcaagcac atccttgaac aaatcaagca
    26281 agaattagat agaaggcgtc tattggacct ccctggtggt attgtcttaa tcggtgggaa
    26341 tgccatttta ccaggtatgg ttgagcttgc tcaggaagtc tttggcgtcc gtgtcaagct
    26401 ttatgttcca aatcaagttg gtatccgtaa tccagccttt gcgcatgtga ttagtttatc
    26461 agaatttgcg ggtcaattaa cagaagttaa tcttttggct cagggagcga taaaaggtga
    26521 gaatgactta agtcatcagc caattagttt tggtgggatg ttgcaaaaaa cagctcagtt
    26581 tgtacaatca acgcctgttc aaccagctcc tgctccagaa gtagagccgg tggcgcctac
    26641 agaaccaatg gcggatttcc aacaagcttc acaaaataaa ccgaaattag cagatcgttt
    26701 ccgtggcttg atcggaagca tgtttgacga ataaagagga aaaataaatt atgacatttt
    26761 catttgatac agctgctgct caaggggcag tgattaaagt aattggtgtc ggtggaggtg
    26821 gtggcaatgc catcaaccgt atggtcgacg aaggtgttac aggcgtagaa tttatcgcag
    26881 caaacacaga tgtacaagca ttgagtagta caaaagctga gactgttatt cagttgggac
    26941 ctaaattgac tcgtggtttg ggtgcaggag gtcaacctga ggttggtcgt aaagccgctg
    27001 aagaaagcga agaaacactg acggaagcta ttagtggtgc cgatatggtc ttcatcactg
    27061 ctggtatggg aggaggctct ggaactggag ctgctcctgt tattgctcgt atcgccaaag
    27121 atttaggtgc gcttacagtt ggtgttgtaa cacgtccctt tggttttgaa ggaagtaagc
    27181 gtggacaatt tgctgtagaa ggaatcaatc aacttcgtga gcatgtagac actctattga
    27241 ttatctcaaa caacaatttg cttgaaattg ttgataagaa aacaccgctt ttggaggctc
    27301 ttagcgaagc ggataacgtt cttcgtcaag gtgttcaagg gattaccgat ttgattacca
    27361 atccaggatt gattaacctt gactttgccg atgtgaaaac ggtaatggca aacaaaggga
    27421 atgctcttat gggtattggt atcggtagtg gagaagaacg tgtggtagaa gcggcacgta
    27481 aggcaatcta ttcaccactt cttgaaacaa ctattgacgg tgctgaggat gttatcgtca
    27541 acgttactgg tggtcttgac ttaaccttga ttgaggcaga agaggcttca caaattgtga
    27601 accaggcagc aggtcaagga gtgaacatct ggctcggtac ttcaattgat gaaagtatgc
    27661 gtgatgaaat tcgtgtaaca gttgttgcaa cgggtgttcg tcaagaccgc gtagaaaagg
    27721 ttgtggctcc acaagctaga actgctacta actaccgtga gacagtgaaa ccagctcatt
    27781 cacatggctt tgatcgtcat tttgatatgg cagaaacagt tgaattgcca aaacaaaatc
    27841 cacgtcgttt ggaaccaact caggcatctg cttttggtga ttgggatctt cgccgtgaat
    27901 cgattgttcg tacaacagat tcagtcgttt ctccagtcga gcgctttgaa gccccaattt
    27961 cacaagatga agatgaattg gatacacctc catttttcaa aaatcgttaa gtaaatgaat
    28021 gtaaaagaaa atacagaact tgtttttcga gaagttgcag aggctagtct gagtgctaat
    28081 cgagagagtg gttcggtctc tgtcattgca gttaccaagt atgtagatgt accgacagcg
    28141 gaagccttgc ttccgctagg tgttcatcat atcggtgaaa atcgtgtaga taagtttctg
    28201 gaaaaatatg aagctttaaa agatcgagat gtgacttggc atttgattgg taccttgcaa
    28261 agacgtaagg tgaaagatgt cattcaatac gttgattatt tccatgcatt ggactcagta
    28321 aagctagcag gggaaattca aaaaagaagt gaccgagtca tcaagtgttt ccttcaagta
    28381 aatatttcta aagaagaaag caaacacggt ttttcgagag aggaactgct ggaaatcttg
    28441 ccagagttag ccagactaga taagattgaa tatgttggtt taatgacgat ggcacctttt
    28501 gaggctagca gtgagcagtt gaaagagatt ttcaaggcga cccaagattt acaaagagaa
    28561 attcaagaga aacaaattcc aaatatgcct atgaccgagt taagtatggg aatgagtcgt
    28621 gattataaag aagcgattca attcggttcc acttttgttc gtataggtac atcatttttt
    28681 aagtaggaga gaaccatgtc tttaaaagat agattcgata gatttataga ttattttacg
    28741 gaggatgagg attcaagtct cccttatgaa aaaagagatg agcctgtgtt tactccagta
    28801 aattcttcac aggaaccggc tctcccaatg aatcaacctt cacagtcggc tggtacaaaa
    28861 gagaacaata tcaccagact tcatgcaaga caacaggaat tggcaaatca gagtcagcgt
    28921 gcaacggata aggtcattat agatgttcgt tatcctagaa aatatgagga tgcaacagaa
    28981 attgttgatt tattggcagg aaacgaaagt atcttgattg attttcagta tatgacagag
    29041 gtgcaggctc gtcgttgttt ggactatttg gatggagctt gtcatgtttt agctggaaat
    29101 ttgaaaaagg tagcttctac catgtatttg ttgacaccag tgaatgttat tgtaaatgtt
    29161 gaagatatcc gtttaccaga tgaagatcaa cagggtgagt tcggttttga tatgaagcga
    29221 aatagagtac gataatgatt tttttaattc gtatgattta taatgcagtg gatatttact
    29281 ccctgatttt ggtagccttc gctgtcatgt cttggtttcc aggtgcctac gaatccagtt
    29341 taggtcgttg gattgtagcg ttggtgaaac cagtgcttgc tcccttgcaa cgcctgcctt
    29401 tacagatagc gggtcttgat ttatctgttt gggttgcgat tgttttggtt cgatttttag
    29461 gagaaaacct agtgcgtttt ctggcgatga taggatgaat aaagggattt atcagcattt
    29521 ctccatagaa gatcgtccat ttcttgacaa gggaatggaa tggataaaga aggtagaaga
    29581 tagctatgct ccttttttaa ctccttttat caatcctcat caggagaagc tattaaagat
    29641 tttggccaaa acctatggtc ttgcttgtag cagtagtggg gaattcgtat cgagtgagta
    29701 tgttcgagtt ttattatacc cagattattt ccaaccagag ttttcagatt ttgaaatatc
    29761 tctccaggaa attgtgtatt ccaataaatt tgaatattta acgcatgcta agattttagg
    29821 gacagtcatc aatcaattag ggattgaacg gaaacttttt ggagatatcc tagtagatga
    29881 agaacgggcg cagattatga ttaatcagca gtttcttctt ctctttcaag atggactaaa
    29941 gaaaattggt cgtatacctg tttcgctgga ggaacgtcct ttcaccgaga aaatagataa
    30001 gctagaacag tatcgagaac tggatttatc tgtgtctagt tttcgattag atgttctttt
    30061 atcaaatgtt ttgaaactat ctaggaatca agcaaaccag ttgattgaaa agaaacttgt
    30121 ccaagtaaat tatcatgtgg tagacaaatc agattacact gttcaagttg gagacttgat
    30181 tagtgtgaga aaatttggtc gcttgagatt acttcaagat aagggacaaa cgaaaaaaga
    30241 gaagaaaaaa ataaccgtcc agttattatt aagtaagtga ggaatagaat gccaattaca
    30301 tcattagaaa taaaggacaa gacttttgga actcgattca gaggttttga tccagaagaa
    30361 gtcgatgaat ttttagatat tgtggttcgt gattacgaag atcttgtgcg tgcgaatcat
    30421 gataaaaatt tgcgtattaa gagtttagaa gagcgtttgt cttactttga tgaaataaaa
    30481 gattcattga gccagtctgt attgattgct caggatacag ctgagagagt gaaacaggcg
    30541 gcgcatgaac gttcaaacaa tatcattcat caagcagagc aagatgcgca acgcttgttg
    30601 gaagaagcta aatataaggc aaacgagatt cttcgtcaag caactgataa tgctaagaaa
    30661 gtcgctgttg aaacagaaga attgaagaac aagagccgtg tcttccacca acgtctcaaa
    30721 tctacaattg agagtcagtt ggctattgtt gaatcttcag attgggaaga tattctccgt
    30781 ccaacagcta cttatcttca aaccagtgat gaagccttta aagaagtggt tagcgaagta
    30841 cttggagaac cgattccagc tccaattgaa gaagaaccaa ttgatatgac acgtcagttc
    30901 tctcaagcag aaatggaaga attacaagct cgtattgagg tagccgataa agaattgtct
    30961 gaatttgaag ctcagattaa acaggaagtg gaaactccaa ctcctgtagt gagtcctcaa
    31021 gttgaagaag agcctctgct cgtccagttg gcccaatgta tgaagaacca gaagtagctc
    31081 cagtgcatcc gacaggtcca acaccagcta cagaaactgt tgattcagca ccgggatttg
    31141 aagcaccgca agaatctgtt acaattttat aagaaatatt ctgagaacaa tatcttatcc
    31201 ttatattccc agcgagcagg agatggtgtg agtcctgcat tccctatcga taagattatc
    31261 ctctcaaact atcaagtctg aatctagtaa gatttgacgt tccccacgtt acgggataag
    31321 agggagaaag actaaaactt tttccgaata aaggtggtac cacgattttc gtcctttttg
    31381 gaagtcgtgg tttttaattt gttattattt ataaaggaga taccatgaaa ctaaaagata
    31441 cccttaatct tgggaaaaca gctttcccaa tgcgtgcagg ccttccgacc aaagagccag
    31501 tttggcaaaa ggaatgggaa gatgcaaaac tttaccaacg tcgtcaagaa ctaaatgaag
    31561 ggaaaccgca ttttgtcttg catgatggcc ctccatacgc aaacggaaat atccacgttg
    31621 gacatgccat gaatcatatc tcaaaagata tcatcattcg ttctaagtct atgtcaggtt
    31681 ttaacgcacc ttatatccca ggttgggata ctcatggtct gccaatcgag caagttttgg
    31741 caaagcaagg tgtgaagcgc aaagaaatgg acttggttga gtacttgaaa ctctgtcgtg
    31801 agtacgctct ttctcaagtt tataaacaac gtgatgattt caaacgcttg gggatgtcag
    31861 gtgactggga aaatttatat gtgactttaa ctccagacta tgaagcagcc caaatccgtg
    31921 tctttggtga gatggctaat aagggttata tctaccgtgg tgctaagcca gtttactggt
    31981 catggtcatc tgagtcagcc cttgccgaag cggaaattga ataccatgat ttggtttcga
    32041 cttcacttta ttatgccaat aaggtaaaag atggcaaagg tatcctagat acagatactt
    32101 atatcgtagt ctggacaaca actccattta ccatcacagc ttctcgtggt ttgactgttg
    32161 gtgcagatat tgattacgtt ttggttcaac ctgctggtga aactcgtaag tttgtcgttg
    32221 ctgcagaatt gttgactagc ttgtctgaga aatttggctg ggctgatgtt caagtgttgg
    32281 caacttaccg tggtcaagaa ctcaaccaca tcgtaacaga acacccatgg gatacagctg
    32341 tagatgagtt ggtaatcctt ggtgatcacg ttaccactga ctctggtaca ggtatcgtcc
    32401 atacagcccc tggttttggt gaggacgact acaatgttgg tattgctaat ggtcttgaag
    32461 tcgcagtgac tgttgacgaa cgcggtatca tgatggcgaa tgctggtcct gagtttgaag
    32521 gtcagttcta cgacaaggtt gtaccaactg ttattgaaaa acttggtaac ctccttctag
    32581 cccaagaaga aatctctcac tcatacccat ttgactggcg tactaagaaa ccaatcatct
    32641 ggcgtgcagt tccacaatgg tttgcctcag tttcaaaatt ccgccaagaa atcttggatg
    32701 ctattgataa agttaaattc catacagaat ggggtaaagt acgtctatat aatatgattc
    32761 gtgaccgtgg tgactgggtt atctctcgtc aacgtgcttg gggtgttcca cttccaatct
    32821 tctatgcaga agacggtaca gctatcatga cagctgagac tattgaacat gtggcgcaac
    32881 tctttgaagt acatggttca agcatttggt gggaacgtga tgccaaggac ctcttgccag
    32941 aaggatttac acatccaggt tctccaaatg gggagttcaa gaaagaaaca gatattatgg
    33001 atgtatggtt tgactcaggt tcatcatgga atggtgtttt ggtaaatcgt ccaaatctga
    33061 cttatccagc tgacctttac ctagaaggtt ctgaccaata ccgtggttgg tttaactcat
    33121 cacttatcac atctgttgcc aaccatggcg tagcacctta caaacaaatc ttgtcacaag
    33181 gttttgccct tgatggtaaa ggtgagaaga tgtctaaatc tcttggaaat accattgctc
    33241 caagcgatgt tgaaaaacaa ttcggtgctg aaatcttgcg tctctgggta acaagtgttg
    33301 actcaagcaa tgacgtgcgt atctctatgg atattttgag ccaagtttct gaaacttacc
    33361 gtaagattcg taacactctt cgtttcttga ttgccaatac atctgacttt aacccagctc
    33421 aagatacagt cgcttacgat gagcttcgtt cagttgataa gtacatgacg attcgcttta
    33481 accagcttgt caagaccatt cgtgatgcct atgcagactt tgaattcttg acgatctaca
    33541 aggccttggt gaactttatc aacgttgact tgtcagcctt ctaccttgat tttgccaaag
    33601 atgttgttta cattgaaggt gccaaatcac tggaacgccg tcaaatgcag actgtcttct
    33661 atgacattct tgtcaaaatc accaaactct tgacaccaat ccttcctcac actgcggaag
    33721 aaatttggtc atatcttgag tttgaaacag aagacttcgt ccaattgtca gagttaccag
    33781 aggctcaaac ttttgctaat caagaagaaa tcttggatac atgggcagcc ttcatggact
    33841 tccgtggaca agcacaaaaa gccttggaag aagctcgtaa tgcaaaagtt atcggtaaat
    33901 cacttgaagc acacttgaca gtttatcaaa atgaagttgt gaaaactcta ctcgaagcag
    33961 taaacagcaa tgtagctcaa cttttgatcg tgtctgagtt gaccatcgta gaaggaccag
    34021 ctccggaagc tgcccttagc ttcgaagatg tagccttcac agttgaacgt gctactggtg
    34081 aagtatgtga ccgttgccgt cgtatcgacc caacaacagc agaacgcagc taccaggcag
    34141 ttatctgtga ccactgtgca agcatcgtag aagaaaactt tgcggaagca gtcgcagaag
    34201 gatttgaaga gaagtaaggt tgaaaagtct agagaaaact caatttgaga agaaaagaca
    34261 actaatctta tagtctaaaa aacgcatagt atcacgtttt tgaacacatg atatgatgcg
    34321 ttttttattt attttaaaaa tttgcgaggt atgacttttt atactcaaca agaatcaaag
    34381 agaaacttag caagctaaca gtagtaagat aaaataggaa tttgatatta gggataagat
    34441 tggtaaatag tgtaatattt ttacaacaat aaatttatat
//
LOCUS       DAVHSL010000019        33868 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000019 DAVHSL010000000
VERSION     DAVHSL010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.019"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(229..447)
                     /locus_tag="VVR39_000927"
     CDS             complement(229..447)
                     /locus_tag="VVR39_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU6030439.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            605..679
                     /locus_tag="VVR39_000928"
                     /pseudo
     CDS             605..679
                     /locus_tag="VVR39_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(906..1064)
                     /locus_tag="VVR39_000929"
                     /pseudo
     CDS             complement(906..1064)
                     /locus_tag="VVR39_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1442..2131)
                     /gene="rplA"
                     /locus_tag="VVR39_000930"
     CDS             complement(1442..2131)
                     /gene="rplA"
                     /locus_tag="VVR39_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU6030440.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2339..2764)
                     /gene="rplK"
                     /locus_tag="VVR39_000931"
     CDS             complement(2339..2764)
                     /gene="rplK"
                     /locus_tag="VVR39_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU6030441.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2890..2970
                     /locus_tag="VVR39_000932"
                     /pseudo
     CDS             2890..2970
                     /locus_tag="VVR39_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3073..3789)
                     /locus_tag="VVR39_000933"
     CDS             complement(3073..3789)
                     /locus_tag="VVR39_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEU6030442.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAAGYPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3807..4268)
                     /locus_tag="VVR39_000934"
     CDS             complement(3807..4268)
                     /locus_tag="VVR39_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6030443.1"
                     /translation="MCLICQRIELIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHQMENSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKGHGLNGRGPVWWVPWEEMAAEDCQVQSPEREEMIKILSHELEKHLA"
     gene            complement(4270..5307)
                     /locus_tag="VVR39_000935"
     CDS             complement(4270..5307)
                     /locus_tag="VVR39_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU6030444.1"
                     /translation="MNQTVNYIKELTAIASPTGFTREISEYLVHTLEELGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIDLPMTTHFAFSVFEE
                     VGHGANSNIPEEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5405..6730)
                     /gene="brnQ"
                     /locus_tag="VVR39_000936"
     CDS             complement(5405..6730)
                     /gene="brnQ"
                     /locus_tag="VVR39_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU6030445.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6901..6993)
                     /locus_tag="VVR39_000937"
     CDS             complement(6901..6993)
                     /locus_tag="VVR39_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6030446.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7036..7188)
                     /locus_tag="VVR39_000938"
     CDS             complement(7036..7188)
                     /locus_tag="VVR39_000938"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6030447.1"
                     /translation="MKEIAFDAFYQLYQNDQFSLVDVREVDEFAALHLEGAYNLPLSQ
                     LADSYD"
     gene            complement(7348..7926)
                     /locus_tag="VVR39_000939"
     CDS             complement(7348..7926)
                     /locus_tag="VVR39_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU6030448.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7980..9380)
                     /gene="pepV"
                     /locus_tag="VVR39_000940"
     CDS             complement(7980..9380)
                     /gene="pepV"
                     /locus_tag="VVR39_000940"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU6030449.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9393..9998)
                     /locus_tag="VVR39_000941"
     CDS             complement(9393..9998)
                     /locus_tag="VVR39_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU6030450.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10169..10969
                     /locus_tag="VVR39_000942"
     CDS             10169..10969
                     /locus_tag="VVR39_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6030451.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVVATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11151..11984)
                     /locus_tag="VVR39_000943"
     CDS             complement(11151..11984)
                     /locus_tag="VVR39_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6030452.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELEFAKSKGLPFIEMYEELRREDNYQRHNLELLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(11974..13818)
                     /gene="uvrC"
                     /locus_tag="VVR39_000944"
     CDS             complement(11974..13818)
                     /gene="uvrC"
                     /locus_tag="VVR39_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU6030453.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGHDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELDLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEAHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP"
     gene            complement(13857..14558)
                     /locus_tag="VVR39_000945"
     CDS             complement(13857..14558)
                     /locus_tag="VVR39_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU6030454.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14637..15869)
                     /gene="murN"
                     /locus_tag="VVR39_000946"
     CDS             complement(14637..15869)
                     /gene="murN"
                     /locus_tag="VVR39_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU6030455.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFCYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15874..17094)
                     /gene="murM"
                     /locus_tag="VVR39_000947"
     CDS             complement(15874..17094)
                     /gene="murM"
                     /locus_tag="VVR39_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU6030456.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRSLEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17206..17985)
                     /locus_tag="VVR39_000948"
     CDS             complement(17206..17985)
                     /locus_tag="VVR39_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6030457.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKIFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18054..19715)
                     /locus_tag="VVR39_000949"
     CDS             complement(18054..19715)
                     /locus_tag="VVR39_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6030458.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19890..22112)
                     /gene="recJ"
                     /locus_tag="VVR39_000950"
     CDS             complement(19890..22112)
                     /gene="recJ"
                     /locus_tag="VVR39_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU6030459.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEYLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVTGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22389..23147
                     /locus_tag="VVR39_000951"
     CDS             22389..23147
                     /locus_tag="VVR39_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6030460.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LSPIKVLGIDKKEAEKTAQKYLEFVNIWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            23187..23951
                     /locus_tag="VVR39_000952"
     CDS             23187..23951
                     /locus_tag="VVR39_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6030461.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23964..24641
                     /locus_tag="VVR39_000953"
     CDS             23964..24641
                     /locus_tag="VVR39_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6030462.1"
                     /translation="MTDLSSWTAYFQDFEQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24651..25310
                     /locus_tag="VVR39_000954"
     CDS             24651..25310
                     /locus_tag="VVR39_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6030463.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVHNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYKAGMSQGFTSAQILYYIILPQASRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25605..26795
                     /locus_tag="VVR39_000955"
     CDS             25605..26795
                     /locus_tag="VVR39_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU6030464.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLCRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27116..27997)
                     /locus_tag="VVR39_000956"
     CDS             complement(27116..27997)
                     /locus_tag="VVR39_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU6030465.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28138..29466)
                     /gene="vncS"
                     /locus_tag="VVR39_000957"
     CDS             complement(28138..29466)
                     /gene="vncS"
                     /locus_tag="VVR39_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU6030466.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29463..30119)
                     /gene="vncR"
                     /locus_tag="VVR39_000958"
     CDS             complement(29463..30119)
                     /gene="vncR"
                     /locus_tag="VVR39_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU6030467.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30168..30254)
                     /gene="pep27"
                     /locus_tag="VVR39_000959"
     CDS             complement(30168..30254)
                     /gene="pep27"
                     /locus_tag="VVR39_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU6030468.1"
                     /translation="MYEKGFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30430..31809)
                     /gene="vex3"
                     /locus_tag="VVR39_000960"
     CDS             complement(30430..31809)
                     /gene="vex3"
                     /locus_tag="VVR39_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU6030469.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31861..32508)
                     /gene="vex2"
                     /locus_tag="VVR39_000961"
     CDS             complement(31861..32508)
                     /gene="vex2"
                     /locus_tag="VVR39_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU6030470.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32521..33798)
                     /locus_tag="VVR39_000962"
     CDS             complement(32521..33798)
                     /locus_tag="VVR39_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030471.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9642 a         7716 c         6264 g        10246 t
ORIGIN      
        1 tatacataaa ctaacctcct cattattagc aaggcttcta ctgattataa cctaattctt
       61 agactacttc aagactaact gtccaataat aatctacaga taaatcatcc actcttaatc
      121 aaattttatt caatccatct actcattccc aaaaggttgc tgtataatgc aagacatttt
      181 tcttactgct tttacttttc cttaccctca atttagtgag ctaataaatt attcttcttc
      241 aaaaggttga gatttatcta gtaactctaa aacattaatg gtaggtagca acattgcttc
      301 actgctatca attgccgaaa ctattgaaac aatagaacgt aaataaggat aaagaatagc
      361 agtaccattt acgtatagaa tatcggtgat attttcatct atatttattt caaaatatcc
      421 tattacagtt acagatattt ttttcatggc atctttgtca actaaagaaa cactaagttt
      481 tacggctcca tgactataat catctgtatg accaacctta actatgggat ataatatatc
      541 gaaggtaaat gtgaacaaac tgattaggaa atttaaacca acttctaaca atgtgttata
      601 ctcaatgaaa accaaagagc aaactaggaa actagcctca ggttgctcaa aacactgttt
      661 tgaggttgta gatggaactg acgtagtcag ctcaaaacac tgttttgagg ttgtggatag
      721 aactgacgaa gtcagtaacc atacgcacgg caaggcgaca ttgacgtggt ttgaagagat
      781 tttcgaagag tattagaaag ctcgatggac tattccagat tcattccact agatttcgaa
      841 atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgtcgt tcggcatacg
      901 gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt
      961 ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact
     1021 aattgatagt ggtcccccca cccagatacc ttatccgcta tataggcctt attatcacgt
     1081 tcctgttcgt agagccacga tttcgctatc tcttcctctg acgattctta tttccagcgt
     1141 cagacttaaa acggtctatc cccagaccgt tttaatccgc tacctcacga tagtcagact
     1201 tgggaatcgc tattgggttc accggtagca ggtgcccacc gaggacttac acctcaaata
     1261 tataataaaa tgaaataaga acaggacgaa tcgatcagga cagtcaaatc aatttctaac
     1321 aatgttttag aagtagatgt gtactattct agtttcaatc tactatacaa catgcccgtc
     1381 gtacatcaaa aaaagttgag acatagcgtc ttcaactttt ttacattact ttaactactg
     1441 attaaagtga gtttacgtca actttgatac caacaccttg agtagttgtg atagtcaagt
     1501 ttgttacgta agttccttta gctgtagctg gttttgcttt ttggattgtt tcgttgaaag
     1561 ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg attgcttgaa
     1621 cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct tcaactgctt
     1681 tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta cgtggtccaa
     1741 ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata actacgtcga
     1801 agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca aagtctgcac
     1861 cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca cgtgaagttt
     1921 taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct tttttaacgt
     1981 cgatgttcaa gttgtaagca acttctacag ttgcatcaaa ttttgcaaag ttagtttctt
     2041 ttgcaagtgc tacagcttct tctacactgt atgcttttgt gctgtcgatt ttctcaagag
     2101 cagcacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag tggttcaatc
     2161 gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt tcagtctact
     2221 atttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag cctcagtcac
     2281 ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt gttattgatt
     2341 agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc attgcagact
     2401 ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt acttgtgcac
     2461 gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca acacctgcag
     2521 cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat gatttatctt
     2581 cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta cgagcgttga
     2641 actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt ccaaccggtg
     2701 gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg acttttttag
     2761 ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac ctcccacaag
     2821 tatgtttttc acatacccat ccattataca ctatttatct ggaattgcaa gagaaaagtt
     2881 tattttttgt actcaatgaa aatcaaagag caaactagga agctagccgc aggctcctca
     2941 aagtacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca ctgttttgag
     3001 gttgtgaata gaaccgacgt agtcagtagg taaggcgacg ctgacgtggt ttgaagagat
     3061 tttcgaagag tattaatcga cgtagtctcc gccttcaaag ccatagtatt cttccaaact
     3121 gagaccactt gcagcaattt ctttagcttc ttttcctaca taacgcaggt gccattcctc
     3181 agccatatag cctgtttcct tttccttgcc tttgagataa cggacaacaa agccataatc
     3241 agctgcatga tccaagagcc attgggctgc tttttcttct gtcaccaaat caccatcagt
     3301 cccaatcaca tcaaaggcca agcctgtctg gtgttcgcta tagccaggac gggcagagta
     3361 acggtcagct gctgcctttc catcttggtt gacataatct tgatagagct tggtctgagt
     3421 ttcataactt ctaaaaccac tgtagtgatc gctgattggg tagccagctg cttgcattgc
     3481 tgcaatgagt ttcagcaact ctgccttggc tgttggattt tctcctggat tgtagtcttt
     3541 tgacaaagga taacgtttat tagctaggat aatttcatcg tatttccctt gaatactata
     3601 atagctccct ttattgctaa cttctgcctt tttctgacta gaagcttgag atttgctgcc
     3661 tacagttcct tccggttgac tgctttgctc cgtcttttga gtattttctt caactttcgt
     3721 tttttcttgc gaacaagctg caagagtcaa tgctagtaaa ccagataaaa tgacatatct
     3781 ttttttcatt tctttcttcc tctctcttag gccaaatgct tctccaattc atgagataag
     3841 attttaatca tctcttcccg ctctggcgat tgcacttggc aatcttctgc tgccatttct
     3901 tcccagggca cccaccagac tgggccacgg ccattaagtc cgtgcccttt catatcacct
     3961 gctcttcgcg gaaaaagatg ccaatgagcg tgggcatcgc catttcctag gagttcaata
     4021 ttcatctttt cagcctcaaa tgctttggcg actgcttctt gaaccaaact catttcctct
     4081 aaaaagcgaa gttttacaga attctccatt tggtggagtt ctgtaacatg ttcttttgct
     4141 aaaaataagg tatagccctt aaagtattgg tggtctccaa taactacata gcccgtttct
     4201 agttctttga caaagtaggg attttctcca gctttgatga gttcaattct ttgacagatt
     4261 aagcacattc tatgataccg cctcactctt gagataggca tctaccatac gctcagtcgc
     4321 cactactgaa tcaatgtgtg tgcgctcata agagtgactg gactcgattc ccgctccaag
     4381 aagtgcatgc ttgacctctg cacctgctga catcgctgct gaagcgtccg atccataaaa
     4441 tggatagata tccagcttaa atggaatatc ttgctctttc gccaaagcta ctaagtgttg
     4501 acggaagtca tagtgataag gaccggaagc atccttgaca cagatagata ctgtgtactc
     4561 atccgtctgt tggtcatcgc ccatagctcc catatccaca gccagatatt ctactacctc
     4621 ttctggaata tttgaattgg caccatgccc cacttcttca aacactgaaa aagcaaagtg
     4681 tgtcgtcatc ggcaagtcaa ttccttcttc tttataaact cgaaggagat tgagcaaaat
     4741 ggctgcactg actttgtcat ccaagtggcg agacttgata aaaccagttt ccgtcacaac
     4801 tgttcgcgga tcaaaactaa taaagtcacc aacctcaata cccaaggcac gtgtttcttt
     4861 ttcattggtc actttttcgt ctaaacgcac ttccatattg tcctgagtgc gttcagcagt
     4921 tcctgcatct ttgtagacat ggcaagatgt ctggtggata aggatagttc cagataccgt
     4981 tttacctgta ctagccacat gaacggtaca gttttctccc tcaatcatgt tccaaggaaa
     5041 accaccgata cggtccaatt tgagacgtcc gtcaggtttg acagcacgta caatggctcc
     5101 gagtgtatcc acatgggcgg ttacatagcg atgttgttca tcattttgac ctttaatggt
     5161 cacattgaca ccgcccttgg ctgtacgaac cggctggtaa ccaagttctt ctaaagtatg
     5221 gactaggtat tctgaaatct cacgagtaaa gcccgttgga gatgcaatag cggttaattc
     5281 tttgatatag tttacagttt gattcatttc ttcacctctt tcgctaccta ttataacaca
     5341 tttatcatcg gataaaaaaa gaaaatcact cctgtagact tggctacaaa agtgatttaa
     5401 gtgattattc catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca
     5461 agattccaac aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc
     5521 taacaagatt tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa
     5581 taactgtaac cacagcaatt gtcaactgca tacctggttt tgaaagggca acaaatttgt
     5641 tgacaatgac aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa
     5701 ttgagtactt gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa
     5761 aggctgtcgc ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg
     5821 ttgacacaat caaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga
     5881 agagttgagc tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg
     5941 gtgttccacc cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac
     6001 cgatgtaaag agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa
     6061 tgtattcttt cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacgctaa
     6121 aggccactga ggcaagggcg tccaaggtat tgtaaccttc taggaaacct gtaccaaagg
     6181 cagaagcttg ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc
     6241 ccagaacgac caagataaca atcaaaattg caaagactgg cgttaaaata cgtccaatgc
     6301 ggtctaagat ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg
     6361 taaatacaat caagccaagt cctttatttg catccgacaa aagggggcta atccctactt
     6421 cgtaagctgt tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa
     6481 ctgagaggta aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatatc
     6541 ctttaggatt tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga
     6601 caaaacctgc gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa
     6661 aaatcaagtt ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt
     6721 ttttagccat aaaaatctcc ttcatattta taaaatactg acctagtata ccacgattag
     6781 gagtctgaaa aaagcatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag
     6841 aattatctaa aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt
     6901 ttaaagttct tcaaaggcta acatgccacc ctggacattg ataacattat aaccttgttc
     6961 taataggaat tggcaagcac gcgccgatct cattccagat ttgcaaataa tataatgcaa
     7021 gcgatctttg tccaattaat cataactatc agccaattga ctaagcggta ggttgtaggc
     7081 accttctaaa tgaagagctg caaactcatc cacttctctc acatccacta gagaaaactg
     7141 atcgttttgg taaagctggt aaaatgcgtc aaaggctatt tctttcattc tttttcttct
     7201 aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc gtatgttacc
     7261 gacttcgtca gttttatctg caacttcaaa gctgtacttt gagcagccta cgactagctt
     7321 cctagtttgc tctttgattt tcattgacta taaaatcgtt ttaattcttt ttttcaaatc
     7381 tggcactact tctgcctcaa accaaggatt tttggccatc cagatttgat ttcgtggtga
     7441 tgggtgaact agcggaaaat aggctggcag atagtcttta tagtgtttca ccctctccgt
     7501 taccttccca ctgattttct cctgtaaata gtaggcttgg gcatattgcc caatcaagag
     7561 ggttaactga atatcaggca attcctgtaa gagttgcgga tgccattttt ctgcaaaacc
     7621 tgtacgaggc ggaagatcac ccgacttgcc atgtcctgga aagtagaaat ccataggcaa
     7681 aacagcaaaa taacctgaat tgtaaaaggt atcttcatcc acacctagcc agtcccgcaa
     7741 acggtcacca cttttatctt tccagtaaag gcctgcttct tgagttttaa gtcccggagc
     7801 ctgaccgatg atattgatgc gagcagtttt tggcgctgca aagagaggct caatgccacg
     7861 ctctgtatag ctggcattct gcgaatccgc catgatagcc tgtttgattc tttcgatttg
     7921 agacatctac tttccctcca aaaagaagtc caagcataag atctcagact tctatcgttt
     7981 tatttgatca attcgtaaat agcttcggca taaattgctg ctgctcggaa gagatcgtcc
     8041 aaggcaataa attcattggc ttggtgcatg gtatcaattg agtctgggaa catagcacca
     8101 taggcaactc cgcgctctaa caagcgacca aaggttccac caccgatgac ttgttcatga
     8161 cctttaaggc ctgtttgttt ttcatagaca ttcaacaagg tttgcacaag tggatcttcc
     8221 attggcacat agtgaggggt atgaccatgt tctgatagac tgacagaagc aactggcaag
     8281 ttttctagga ttgacttgat ttgttctgga cttgttcctt ttggatagcg gatgttaagg
     8341 gcaatggtat tatcagcact tgtttcatcg aagcggaaga cgccggcatt catagaaaga
     8401 gcacccatct tttcatccac atgagcaatc ttgagatttt caccctcatg atcgttcaag
     8461 agaattttac ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc aaactggctg
     8521 aggaagaggg caaggtaagt tgcgccattg acacctgaag caggcatagc accgtgggct
     8581 gatttaccaa tgatcgtcac cttgtattgg ccagcttctt cttggagttc tcctctaagt
     8641 ttgtgttctg caacaaaggc atctagttta gcttgcaagt ctgtcaagtc acctgaaacg
     8701 actgctgttg ctgattctgg taccatattt tcacgtaaac cacctgtaaa gctgtgaaga
     8761 cgggctgcac ctgtattttc acctgcaaag tggaggtatt ccgtgatatt tcctttttca
     8821 ccattgatga ttggaaattc agcatctgga gagaaaccaa agtctggctt cgcaagtcct
     8881 acgtgctcaa agtagtagtc catgtctgcc cagcctgatt cttcgtctgt tccaacgatg
     8941 aagcgaactt tcttagaagt tggaagaccc aattctttga tgattttcaa accatagtaa
     9001 caagctgttg taggaccctt atcgtccgaa gccccgcgcg cataaaggcg accatctttg
     9061 atagttggtg tgtaaggatc tgtatcccaa ccgctaccag ctggaaccac gtccatatgg
     9121 gcaaagattc cgagaacttc ttctccatca ccaaactcaa aatgtcctgc gtagttatcg
     9181 acattcttag ttgggtagcc atcacggtct gcgatttcaa ggaatttttc caaggctttt
     9241 actggaccag gtccaaatgg atgctgggca tcagccttgc tatcatcacg ttctgagttg
     9301 atttccaaaa ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc tacttctgct
     9361 gtaaaatcaa ttgctatcat tttttcttct tcctatcttt tttcgatgat ttcatctact
     9421 ggcaagcggt agcttggttc caatttttcg tctgtgtaac ccactgtgat caagagttct
     9481 gggcggaaac ggtcttcaat ttccaaaacc tcattgactt ttgatttgtc aaatccaaga
     9541 ataatgttag aaccaattcc ttggtctgtc aatgcaagaa ctaagttcat ggcaaccaaa
     9601 cctgcattga gagctaggta gtcgctgact tgttgctcac tgtaacgggc aaactcagct
     9661 ggcagatttt tcataaaata ttgaagttgc tcttcagaaa agttattagc gccaccaaca
     9721 cgggcaatct tacgagcacg tttggctaag tccgtatctg taaacaaggc aatggttaca
     9781 ggcgctgatg atacctgctc aaagtttgaa ccataagcca actttgccag ttcagcattt
     9841 ttctcacgaa caactacaaa tttccaaggc tggctgttgt gggcgcttgg cgccaaggtt
     9901 gcaatttcga tagccgtacg cacatctttg ggatcaacag gcttatcagt gaaatgcttg
     9961 gtcgcatgac gttttttatt taattcaaga aatttcataa tcgatttcct tttctaattc
    10021 tactgcttcc attctaccat aatttgaaag agcttgcagg gatttttcat gattaagttt
    10081 ttctatcaca gacataaaag atatatattg gtttatcagg aaagtttctg ataaactagc
    10141 aagtacttta catttgaatg gagacagtat gaaaaaattt agcctattac tagctatcct
    10201 accatttttg gttgcctgtg ggaatcaagc tacacccaaa gagtccagct ctcaaaagac
    10261 aatcgtcgtt gctacagctg gcgatgtgcc accgtttgac tacgaagata aaggtaatct
    10321 gacaggcttc gatatcgaag ttctaaaggc agtagatgaa aaactcagcg actacgagat
    10381 tcaatttcaa agaaccgcct gggaaagtat cttcccagga cttgattctg gtcactatca
    10441 agctgcggcc aataacttga gttacacaaa agagcgcgct gaaaaatacc tctactcact
    10501 tccgatttcc aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt tgacttctct
    10561 tgaccagatc gctggtaaaa caacacaaga ggataccgga acttctaacg ctcaattcat
    10621 caataactgg aatcagaaac acactgataa tcccgctaca attgattttt ctggtgagga
    10681 tattggtaaa cgaatcctag accttgctaa cggagagttt gatttcctag tttttgacaa
    10741 ggtatccgtt caaaagatta tcaaggaccg tggtttagac ctctcagtcg ttgatttacc
    10801 ttctacagat agccccagca actatatcgt tttctcaagt gaccaaaaag agtttaaaga
    10861 gaaatttgat aaagcgctca aagaactcta tcaagacgga acccttgaaa aactcagcaa
    10921 tacctatcta ggtggttctt acctcccaga tcaatctcag ttacaataac actcttcgaa
    10981 aatctcttca aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccta
    11041 cggctagctt cctagtttgc tctttgattt tcattgagta taagatatac taaaagcgat
    11101 gggatcagcc aatcgctttt ttagtttgca ttggttattt taggaaactc ttacaaaaaa
    11161 tcaaaaaaat tcttcacatc ctctacatac ctatgctttt ctattaagct tgctaatagt
    11221 tccagattgt gcctctgata gttatcttca cgacgtagtt cttcatacat ttcgataaag
    11281 ggaagcccct tggatttggc aaattctaac tcagcctcgt aatcataagc gactttacga
    11341 aataggatat ttaccaattc cccatcttca acctctatca cggcatactg ggcacggtga
    11401 ttttttaacg cctcccaatt aaaatagggc atgccaatcg accctggatt gatgatttgt
    11461 tgcccttgac taccataacg aagcaactgc ttgtgaacat gaccataaac tgccacgtcc
    11521 gtttccgcat ctagcagttg gtcaaatttc tctgtatcat tctcaactag caagtcacca
    11581 ccatagtttt tgtcaggtaa attatgagag atagaaaagc gcaatccgtc aatttctttc
    11641 ttttccagca aaggcaagct tcgtagccag acaatcgttg caggatccat tcgctccatc
    11701 aaatactgtg tcatacgcaa gagctgaact tcctgtgggt cttctaagcc atattgccca
    11761 tctaaagcct caaggacacg atcatcccaa ttgcctcgaa cacttgctgt gataggaagg
    11821 tcctttagca gggcgactaa gtcatttgcg cctggaccag gaagaaaaat atctcccaga
    11881 agccagtatt cactgactcc ttgattttta gcatctgcaa tcactgcttc tagcgccgtc
    11941 acattgccat gaatatctga taaaattgcg attttatggt ttattgtggt ttccttccgt
    12001 ttggtaatct actctttctt ctgctacttg aggcaaggct tctccctgcg ggttcaactt
    12061 tctttgcaca gcctctgcaa cgactctagg taccccaact tcgacaatct catccacact
    12121 ggcttccttg attttggtca aagacttgaa atgcttcata agattttgct tgcgtttagg
    12181 tcccagacca tcaatcccat ccaattgaga tgagaaagaa tttttggagc gcagttggcg
    12241 gtggaaggtg atggcaaagc ggtgcgcctc atcttggatg cgttggagga ggaaaaattc
    12301 ctgagaattg cgagacaagt ccaccacttc cagcggatct ccaaagagca attcatgggt
    12361 ttggtgctta tcattctttt gcagacctgc aattggaata tccaagtcca gttcttcttg
    12421 gatgacttgc ttagcaatat tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg
    12481 aggagtcaaa gcctcacgct gtactcgacc atagcgtctg cgaatgacct ctcgcatact
    12541 ggcatagtcg tctggcccga ctacggtctt gattttatac ttacggtaat ccttcttact
    12601 aggcttgccg ttgacaaaga ccaccatagc cgaaacaggg ctagttccca tgatattaga
    12661 gttatcgaag gactcgatac gtactggggt cgggatttgg agcaaacgcc ctagattttc
    12721 aatagctcct tgagtctttt cgacagattt ttctagcaga ttgaacttct gctctagact
    12781 aacacgagca ttttttatgg ctagattgac cagttgtttt ttctctccac gttgaggctt
    12841 aagaatcttg gaatccacca aggccttgac agcctcttcg tcaatatcct gcggaatcag
    12901 tacctcattg ggaactagat gagatttttc ttgatagaat tgtcctacat aggtcaaaaa
    12961 atcctcatct ggatcattga agtaggggaa gagattgaca tcgcgctcga taagcttacc
    13021 ctgacggaca aagaaaacct gcacacacat ccagccctta tccacatagt agccaaagac
    13081 atcgcgattt tgcaaatctt tcgccatgac ccgttgcttg gttcgaagcg ttccaatagc
    13141 ctgaatcagg tcacggtatt ccgccgcacg ttcaaactcc atactttgtg ctgctactgc
    13201 cattttactc ttgagatcat cgatgatttt gtcatcatga cctttcagaa aatcagacac
    13261 ctcctgagcc atagacttga aataagcctc atccttctta cagatggtgt gggccataca
    13321 ctggccgata tggtaataaa aacaaacctt agagggcggg ttggtacatt ttcgaaaagg
    13381 gaaaatccta tctagaagtc gcttgatttc attggctgcc cccacatctg gataaggtcc
    13441 aaaataaaga cctccgtcct ttttgacctg acgagtgata atcaagcgtg gatagcgctc
    13501 attggtgatt ttgatgaaag gataggactt gtcatccttg agcatgatat tgtacttggg
    13561 cttgttttcc ttgatcaggt tgatttctag gagaagtgcc tcaatattag actccgtaac
    13621 aataaattca aaatccacaa tttcagacac cagagcctct gtcttggtat catgacttcc
    13681 acgaaaatag gaccgtactc gattacgcag atttttagcc tttcctacat agataatggt
    13741 gccattttta tccttatgaa tgtagcaacc agggctggtc ggcaagagct ctagttttga
    13801 tttaatcaag ttgttcatag ttccattata gcaaaaaagt agggaaagat agtaccctac
    13861 tcactagtct catatatttt tcggaggttt gcaacatcct cttcctggat accataaaag
    13921 gaacctgctg gttgcatgac agacttctca tctgtatggt ccaagccaat cgcatgacct
    13981 aactcatgtt ctgccgtatg gacaaggcgt tcataggagt agccatagta tggattggac
    14041 aaataataat gattcaaccg caccgttacg gacaagaatt gccctgttaa gagattagtt
    14101 tgactttccg cctctcctgc cacaggagtg cctccgtcgt tcatctccgt agccgtaata
    14161 tccgccttac tagactcagt cacgagttca aagttaaaag caccagtttg attccagttc
    14221 tggattgctt ctaaataagc ctcttgaaag cgtgaatcca tctgcggatc caggtaaata
    14281 cgagcagagg cctgtgccca ccttccttca gaatgctggt gactatctgt ctggcttaac
    14341 ttaggcagtt gccctgtttt ctcccattgg tcaatacttt gttgaccaat ttttactgac
    14401 cgttctgctt gctttagcgc tccttgaaaa tccccgttca gataccagag aagtccgaaa
    14461 gcaagcacac ataagagcac aactatccaa accagacgcc aaaacaaacg ccacacaaaa
    14521 gaaaagaaag cccctatcaa acgaaaaagc cagcgcatgt ctctccacct ttctagcaaa
    14581 taagaattat tttactaaaa gaagctaaaa gaaatctaaa tactgacttt ttcatcttaa
    14641 cgtcctacta tttttttgag taactggata gctttgtatt ttaaaggcga tggatggtaa
    14701 cagaaagtac ccgctttgcg tacaatatag ccattaaaat tctgtttaaa acgcaaaaca
    14761 ccatcacttc catcaaaaat cccttgaatg cctaggaagt tgtatttagg tattccacgt
    14821 tttatgcttt ccaacataac atatttttga agcagtgcag gggcatagaa cttattaaac
    14881 tcagtgtagg aaccactaaa gagataagtc gtttcctgag gcatataaac aaataaactc
    14941 ccagctaaaa caatatcttc ttctccatat ttttcaatca agtctcgcgc ttctgctttt
    15001 cgaacttcaa acgtttcaaa ttgactagaa tattctctca gttgattttg ttttttctca
    15061 gaatgaggat ttttactcaa atcaagtcgc aatttgtcca agttttcttc tagtttattt
    15121 tgttcacctt gcaatttgct catatagtcc gaaaaattta agcttgctat gagaaactcc
    15181 gcttgttctc caaaagtatc ataaaaatgc tcataatatt ctaaactttt atcactatat
    15241 tctctacgtt cagaggtttc ttttgttata ttcttaaaaa tcgatagttc ttcacgtttt
    15301 aactttttca accgaatgcc aaaggtttca gcctttttca ccaagggttt accctttttg
    15361 ctaaaacttt taagcaaact cttttcagtt aattcagtta aatctttata gtataaccaa
    15421 tctggttctc cacctgggta acctgttgtt aagccatcaa attgataacc taaatcagtc
    15481 aaatcttgaa taatactttt tttctcagca tctattggat taccttggct atcaaaagtt
    15541 tgataagttt cataaggttt tacaagcaac tctaatacac cattttgctt ggcatattct
    15601 tttaactctg cataaaaaac tggaagagca tcttgttggg tataaatcgg ccccgaattg
    15661 agttccatat gcagaccacc cagcatgggc aagctataaa ccagagctgc aacttgaatt
    15721 tctccttctt gtttcaaagc aagataaaca attcgagccc ctcttttttc tagcaaatcc
    15781 cccatctgga cagattgcat aaaggaacga gaagaaacct gatcagaata agtctgaaac
    15841 tcttctttcg tgagtgttgt tagtgccata tacttacttt ctatgttttt ttcttaatgt
    15901 tttacggaaa tcaagagcaa gtcttaacag aggatagaga ggatgagtgg gcattgtaaa
    15961 ttcacccaag tattcttcaa tcgttggatt aaatttttcc ttaaaatgat aaagtccacc
    16021 attgagagag ttttcaacac cacctaaatt ttgccagacc atacctcgct caaaggcata
    16081 gcgagccgtt tcataccatg ttaaaattgg tgcattgtaa cgtttaaaat catcatccat
    16141 accagcatat atattgacag aggtagtacc aaattccaaa ctcaaagtag ccgctaaagg
    16201 aactctcgct tgacctacat ctatatattc ctgcaagaag gtcaattcct ctaacaaacg
    16261 ttctttttcc ttcttctgcg cttctacttt tgaagttcga gtcgactcag taaacgtctc
    16321 ttccaaggat ctatttttcg ctaactgttc ttctaattct tgcgaacgtt tagaaacatc
    16381 caaggtggcc aaggtgatat aggccttgtc cttaaaatta tctaacaatt ttttataata
    16441 ggcttcattc ctcaaatgaa tctcttttcg cttctcagtt tttttcatca actccgaaaa
    16501 tgaatctaat agttccagtc caccatattg aatctcaagc cctttgtttc gtgctgttcg
    16561 aatagcctgt tttgttgact tggaaagttt atcttcttca aaattttcct tgtatatttt
    16621 cgcctgaata cgaggttgaa tggtgtctcc catttcctcc gtttttcctg accaccttac
    16681 tcccatttgt tgcaaactat caataatagc cagattttca ggaaattctg tcttttcctg
    16741 attgattaaa ctttgagata ggcaaatact tgggtcaaaa gtcacaaaaa ccgctctctt
    16801 actgcgagca taggacttaa tagactgaat ggcaaaattc aagagttctt tatccccata
    16861 atccaatata ggtcctcttg ggatgtaaaa cattttatag cctagcggaa gagttctaat
    16921 caaaatacta gctgtcgcca gtaatttttc ttccctgtaa acaccaaact tctcatgttg
    16981 ccaattagac ttaacttcct cccaagcact actttgtaat acattggcta attcatgttc
    17041 tttgacaaac tgatcatatt ctaatgtggg aatgccaatt tgataacggt acatttccta
    17101 ctctctttcc tccagtattt tattactatt ctactacttt cgtttgaaaa gtctagtgaa
    17161 aacatatttt attttagttc tactccccct atgctgaagt tcaaactaag tcagtctctc
    17221 ttctaatttg aaatcaattg gtagggttgt taaaaaaact tccaattgtt tttcccagta
    17281 gtaccactcg tgagttccag cactatggct ataggtcaca tcaaaaccta gttttttgag
    17341 atttttcact gcgagattat tggcttcgta caagaaatcc tgttcgccac accacgccca
    17401 aagtttggtc tttttatccg attttttagc cagactttca agagaatagg gactagttgt
    17461 ccagtctcta atctctccaa aaacacctct ccagtaggct ggacttccca gattttgact
    17521 ttcaggagaa aagttttgaa agctgagggc acctgaaaaa ctagctgcat gagaaaaacg
    17581 atttgtcgta agagccagtt tgaagcagcc gtagcctccc atagaaagac cagcgataaa
    17641 gatcttttca cgcttgctag tcatattagg gaagaagcgt ttcagaacct gtggcaattc
    17701 ctctgctaga gccgtgtagt agtcaaaacc atactgggta tcggtgtacc aaccattgct
    17761 ggtattgggc ataacaacga tgagattagt tcctcgaagc aagcgttcta cattggtccg
    17821 cttaagccaa ctattatgat tgccagacat cccgtgcaaa aggtacaaga cgggaatatc
    17881 ttcacactct ggttcttcca ctcgattggc atcagggtag aggacattca ccccccactc
    17941 catatccaat acttgtgagt aatactcgat tttcattact gccatgattt tctccttcta
    18001 tttttctata agaaaaagcc gaaactcgac tttctctctg tttatttcaa cgattatttt
    18061 gcttccatga ctactggtaa aatagctgga cgacgcttgg tttggtcaaa gagatacttg
    18121 gtcaaattat ctcgaacctt ccctttaaga tctgcccagt caaagtcatc tccttgaaga
    18181 taatcttcta ccgtttggtt aatcaattct gaactttcac ggagaatatc gcgactcttc
    18241 ttgagataaa caaatccacg cgtgtgaaca cgagccctag ccacaatttt cttctcacga
    18301 cggttgactg taatagccac gatgaaaatt ccatcctctg acaagacctt acggtcacga
    18361 agaacaacat ttccaacatc accaatggca ttcccatcaa ttaagatatc tcctgctgaa
    18421 accgatccag ctggaacaaa gtctccattc tcgtaagcca tggtcgtccc ctttttagga
    18481 atgaagatgc gttctggcaa catcccaact gccatggcag ccttagcgtg agcatccaac
    18541 tcacgatact ccccttggac agggaagagg tacttaggtt gcaaaagatt gatcatcagc
    18601 tgcaaatcac gcacatttcc gtgccctgat acatgtaaac tttgggtaat caatttgaca
    18661 accccacctg cctgataaat catattttcc acacgcgcaa caaaggcttc tttagcaata
    18721 gacggagccg tagcaatata gaccaggtcc ccatccttga tttctacata acgatggcga
    18781 ccaatcgaca tcttacgaag tccattgata ggttcaccca tacgacctgt ctcaagaata
    18841 atcaactcat ggtcttcaaa gcgagacata tctttaggct taatcaagag aatttcgttg
    18901 gctaaagaca acttcttaag acgaatcgct gtgcggacga tattttcaat atcaaatcct
    18961 gtcaagacga tacgtcgacc tgttttatcc gcagcgtcaa aaatctgctg aatacgagaa
    19021 agattactgg aaacagctgc aacgatgata cgaccttccc agtcagcaat agtttgggta
    19081 atttcatccc taacttcact ttcactagcc acctgaatat tgctgtctgc attggccgaa
    19141 tcactgagga gagccaggac gccgtcacga ccaatctctg ccaaacgagc aaaatcagtt
    19201 gcataagatt cactagccgt ttggtcaaat ttgaagtcac ctgtataaac gatgcttcct
    19261 tccgatgtct tcaagacaat tcccagactc tctggaacgg agtaagtcgt agggaagaag
    19321 gaaaccactg tcccaccaaa atcaatctcc gtattctcat caatgacatg gaaatcatta
    19381 aatttcttaa cggcatcatt acctttgaca aagagctttg ccaactcaat ggtcaactca
    19441 gacccaaata caggaacttt agcctctgcc aagagataag gtagagcacc aatggcatcc
    19501 gcatgcccgt gggtcaagaa aaccccagca atacggtcgc tattttcaaa aaggtaatcc
    19561 atgtttggaa tcaccacatc gacccctaat tgttcatttt caggatattt taaccctaca
    19621 ttcaaaacaa aaatggactc tccaatttca gcaatgtaca tattttttcc attctcacgc
    19681 acaccaccaa gtgttgttaa actgatatta ctcatttttc ctccaaaatc ttagtttatc
    19741 ttgattatag ggcaactcta ccctcttatt ctaaaagttc tgatactttc agccgaatct
    19801 tttcctacca ttataccatt tttttgatga ttttcaaaat gaaggtctgt tttcaaaaaa
    19861 gagttgattt cccaactctt tcctaacttc tactcttttt ccatcaaaaa atcataaatt
    19921 tcttgcaccg tacccagcgc catcatttct tggtctttaa cggtttgttt gagattttgg
    19981 taaatttgac tttctcctat ctcccgcttt ggcgcctctt tattgactgt catcacacca
    20041 tcttttatcg tcacaaagcc tagttcttca aatacttgaa tcatcttgac cagcaagatt
    20101 tgttgaatat taagatatgc agccaaatct ttcagcttgt agcgaatatc aaactctggg
    20161 aactggtaaa tagtcttgta caatttggca aactgatctc tagtcccata acctgtcaga
    20221 taataggcct tgtcaatatc atttttgaaa tagacagcag agaaatgctg ttcctgaaaa
    20281 atggtcttca gctgagtaat atcctctgga atgtttttta cgacaacagc ttcactagcc
    20341 gcaagatttg gcagttctcc aggaaaatcc aagactggaa caccttctgg caagactgca
    20401 ttttttccac gaatgttaaa aagttgaaca ccttccactc gcgcatccac catcatcaac
    20461 tggagggcag tttggccatt ccattggttg acagacaatt taaccgctaa ctctagattc
    20521 ttggtttgag aaaactctgt cgcccatctg ccttgaccaa aggctaccac ttcaaaactc
    20581 gcctcaccct tggaaatttt cagctttaga tgggcattac ctgcccccat agtacgagca
    20641 ctttcgacct gaaaattctt gatataaaaa ataggtttct gattatccat tccaaaagga
    20701 gctaaacgtt caaaactttt gaccgtttcc aagctaagtg cctccaaatc caactcttca
    20761 tctaggttta acttattctt gccaccagca tctgcacctt tttcacgaac ataatcttcc
    20821 aaaacctgag ataaatctga gagttgctca acttccagcg tcatacccgc tgcacctgca
    20881 tgacctccaa aggcgatgaa gaggtctcga tggggatcca gagcttcaaa aatatcgacc
    20941 gcttccacac tacgagcact gcccttggca cgaccgtctt ctatattaag aacaatgact
    21001 gtctgtccca attcttccaa taaacgacca gtcacgattc ctagaacccc aggattccag
    21061 ccttccttgg ccaagacctg aaccttcttc tcaggatcca ccatggtctt ggcttcttca
    21121 tagatagact gaacgatttc cttgcgctct tcgtttttct ggtgaatcat aagggcaatc
    21181 tcatgcgctt cctcatcatc aaatccagtc aacaaatcaa tggcaggatt gggatcatcc
    21241 aagcgaccca aggcattcaa acgaggagca atctggaaac caaccgtttc ttctgttact
    21301 tcgttggcag caatcccagc catgtccagc atttcttgca gaccaatgcg ctgggtatga
    21361 cccaacattt ccagaccata ttgaactaag atacgatttt catccgtcag actcaccata
    21421 tctgcaatag ttccaatagc gaccaaatca agcaattcca cttgcacttc ttctaacagg
    21481 gcacaagcca acttgaaagc aactccacaa ccagccaaat atttaaaagg ataatccgca
    21541 tctggatgtt caggatggac aatagcataa gcatctggca gggtttcagg catggaatga
    21601 tggtctgtca caatgacatc tactcccata gactgagcca atgcaatagc ctcatgacca
    21661 gcaaccccat tgtccaccgt cacaatcaag gaaattcctt cttgctcgat aaagtattta
    21721 taaacactag cattagggcc atagccatcg gtaaaacgat ttggcaggta aactcggcac
    21781 tcagcaccaa gttgttccaa actttccttc acaatagaag ccgaagtcat gccatccgca
    21841 tcatagtctc cataaacgag aatattttcc ccttcttcaa tagcctgacg aatccgctcc
    21901 actgccttgt ccatatcatg gagcagataa gcatcatgta agtactccaa ggaaggttct
    21961 aaaaacttct tcagactttc ttggtcctga atccctctct caaacaataa ccgagccacc
    22021 tcaggaccca gtccagcctt cttggctatc tttgtaaaat ccgcatcttc tacctgcagg
    22081 gcaaactgcc attcataagt aggtgttatc aaaaagacat ccactctttc taagaattct
    22141 attgcttcat tataacatga tttagacgtt ttctctatcc agattgcttt tttataacat
    22201 tttatagtat attgaaacta gaatagtaca cctctacttc taaaatattg ttagaaatcg
    22261 atttgactgt cccgatcgat ttttcctgtt cttatttcac tatagtgaat tttttcagat
    22321 atgatttgac aagaacattc ttttattgca gaatcgtgtt ataaaatcta acataaagga
    22381 gttcgctcat ggctttagta gaatttaaaa acgtcgaaaa atattacgga gactaccacg
    22441 cactccgcaa catcaatctc cgttttgaaa aaggacaagt tgttgtcctg cttggacctt
    22501 ctggctctgg gaagtccact cttatccgta cgatcaatgg tttagaggct gttgacaaag
    22561 gaagtctcct agtcaatggg caccaagttg ctggtgccag ccagaaagat ttggtacctc
    22621 ttcgcaagga agtcggcatg gtttttcaac attttaacct ttatccacac aaaacggtgt
    22681 tagaaaacgt gacactttcg cccattaaag ttctaggaat tgataaaaaa gaagctgaaa
    22741 aaaccgccca aaaatatctg gaatttgtaa atatatggga caagaaagat tcctatcccg
    22801 ccatgctatc tggtggacaa aaacagcgga tcgccatcgc tcgtggtctt gctatgcatc
    22861 cggaactcct cctctttgat gaaccaacat ctgctcttga tcctgagact atcggagatg
    22921 ttctagcagt tatgcagaaa ctggcgcatg atgggatgaa catgatcatc gttacccacg
    22981 aaatgggctt tgctcgagag gttgcggacc gcattatctt tatggccgac ggagaagttt
    23041 tagtagatac gacagatgtc gataactttt ttgacaatcc aagcaaacct cgtgcccaac
    23101 aattcctcag caaaattatc aaccacgaaa gtgacaaagt caaataagga ggcgcctatg
    23161 aaaaaaaatt ctttttatca gcattattga ttagcctttt cggccttgct gctgccaaac
    23221 cagtccaggc tgatactagt atcgcagaca ttcaaaaaag aggcgaactg gttgtcggtg
    23281 tcaaacaaga cgttcccaat tttggttaca aagatcccaa gaccggtact tattctggta
    23341 tcgaaaccga cttggccaag atggtagctg atgaactcaa ggtcaagatt cgctatgtgc
    23401 cggttacagc acaaacccgc ggcccccttc tagacaatga acaggtcgat atggatatcg
    23461 cgacctttac catcacggac gaacgcaaaa aactctacaa ctttaccagt ccctactaca
    23521 cagacgcttc tggatttttg gtcaataaat ctgccaaaat caaaaagatt gaggacctaa
    23581 acggcaaaac catcggagtc gcccaaggct ccatcaccca acgcctgatt actgaactgg
    23641 gcaaaaagaa aggtctaacc tttaaatttg tcgaacttgg ttcctaccca gaattgatta
    23701 cttccctgca cgctcatcgt atcgatgcct tttccgttga ccgctctatt ctatctggct
    23761 acactaataa acggacagca ctactagatg atagtttcaa gccatctgac tacggtattg
    23821 ttaccaagaa atcaaataca gagctcaacg actatcttga taacttggtt actaaatgga
    23881 gcaaggatgg tagtttgcag aaactttatg accgttacaa gctcaaacca tctagtcata
    23941 ccgcagatta aggaggatac cctatgacag atttatcatc ttggacagcc tattttcagg
    24001 attttgaaca atttttcaat ggtttcctct ttactcttgc cctagcgatt ggatccttta
    24061 tcctcgccat ggtcttagga atcttctttg gtgccatgtc aaccagtaaa cgtccaattt
    24121 tacgcatttt agctcgcatc tttgttgaat tttaccaaaa tactcctctc ttggtgcagt
    24181 ttgttattgt tttttatggc ctacctctta tcagtgacca tatcatcatg attccaattt
    24241 attggacagc cgttctctgc gtgggactct atcacggcgc ttatatcgct gaggttattc
    24301 gttcagggat tcagtctatt cctagtggtc agatggaggc cgccttgtcg caaggtttta
    24361 cctatatcag tgccatgcgc ttgattacct tgcctcaggc cttccgcatc attctccctc
    24421 cattgaccaa ccaaattgtt aacctcatca agaacacatc tactgtagct atcatctctg
    24481 gagtagactt gatgtttgtg actaagtctt ggtcggctct caacggaaac tatatcccag
    24541 cctttttagg tgctgctctt ctctactttg ccctatgctt ccctgttgcc cagtttggtc
    24601 gcaagatgga gcaagccaat aaaaaagcct attcacttta ggaggttact atggaatcta
    24661 ttttagaaat tttaacccca gataacctag tctttatctt taaaggattt ggcttgaccc
    24721 tctatatttc tctgattgcc atcatcctct ctactatcat cggtaccgtg cttgccgtca
    24781 tgcgaaatgg aaaaaatcct atcttacgca ttatttccag tatttatatc gagtttgtgc
    24841 acaacgttcc caaccttctc tggattttta ctatcttttt ggtgttcaaa atgaagtcca
    24901 caccagcagg tattacagcc tttactctct ttacatcagc agccttggct gagattattc
    24961 gaggcggtct caatgccgta gacaagggac aatacaaagc aggaatgtca caaggcttca
    25021 cctcagccca aatcctctac tacatcattc tcccacaagc cagccgcaaa atgctaccag
    25081 ccatcatttc tcagtttgtt accgtgatta aggataccag tctcctctac tctgttatcg
    25141 ccctacaaga actctttgga gccagccaaa ttctcatggg ccgttatttc gaaccagagc
    25201 aggtcttcag tctttacatc ctgattgccc tcatctactt cagctttaac ctagcaattt
    25261 ctagcctgtc tcatatgcta gccaaacgtt ggcaacaagc tgcagaataa tactcttcga
    25321 aaatctcttc aaaccacgtc agcttcacct tgccgtatat atgttactga cttcgtcagt
    25381 tctatccaca acctcaaaac ggtgttttga gcagcctgcg gctagcttcc tagtttgctc
    25441 tttgattttc attgagtata aacagccact ctccagttca attggagagt tttttgatga
    25501 gagtagatat ttatagacct caatttgaca ccatacattt tctatgataa aatgtaacaa
    25561 attcatttac aacaaatcga aatctaaatg aaatggaatt ttctatgaaa tcagtcaaag
    25621 gactactctt tatcatagct agttttatct tgactctttt gacttggatg aacacttctc
    25681 cccaattcat gattccagga ctagctttaa caagcctatc tctgactttt atcctagcca
    25741 ctcgtctccc actactagaa agctggtttc acggtttgga gaaggtctac accgtccaca
    25801 aattcacagc ctttctctcc atcatcctac taatctttca taactttagt atgggcggtt
    25861 tgtggggctc tcgcttagct gctcagtttg gcaatcttgc catctatatc tttgccagca
    25921 tcatccttgt cgcctattta ggcaaataca tccaatacga agcttggcga tggattcacc
    25981 gcttggttta cctagcctat attttaggac tctttcacat ctacatgata atgggcaatc
    26041 gtctccttac atttaatctt ctaagttttc ttgttggtag ctatgccctt ttaggcttac
    26101 tagctggttt ttatatcatt tttctatatc aaaagatttc cttcccctat ctagggaaaa
    26161 ttacccatct caaacgctta aatcacgata ctagagaaat tcaaatccat ctttgcagac
    26221 ctttcaacta tcaatcagga caatttgcct ttctaaagat tttccaagaa ggctttgaaa
    26281 gtgctccgca tcccttttct atctcaggag gtcatggtca aactctttac tttactgtta
    26341 aaaattcagg cgaccatacc aataatatct atgataatct tcaagccggc agcaaagtaa
    26401 ccctagacag agcttacgga cacatgatca tagaagaagg acgagaaaat caggtttgga
    26461 ttgctggagg tattgggatc acccccttca tctcttacat ccgtgaacat cctattttag
    26521 ataaacaggt tcacttctac tatagcttcc gtggagatga aaatgcagtc tacctagatt
    26581 tactccgtaa ctatgctcag aaaaatccta attttgaact ccatctaatc gacagtacga
    26641 aagacggcta tcttaatttt gaacaaaaag aagtgcccga acatgcaacc gtctatatgt
    26701 gtggtcctat ttctatgatg aaggcacttg ccaaacagat taagaaacaa aatccaaaaa
    26761 cagagcttat ttacgaagga ttcaagttca aataagtaat catactctcc tggaatttcc
    26821 caggagagtt ttttatagcc aaatgaaata agacaggaac gatggaattt tggcattcaa
    26881 atcaattgat aagaatgttt tatagtggag tgaaatagga tacgaacaaa ttgattagga
    26941 aaatcaaatg aatttataga aatcttttag cagttatgtt atcctattct agtttcaaaa
    27001 cgctatagaa gcagcattgt gctagtctag attcagttta ctatactaaa acgagtagct
    27061 tgaaatcaaa aaacccaccc tcacaggcag gttttatctg tattattcag ctagattatg
    27121 ctttaccttc tgaaccgaat acgtcgatac gttcttcaac cgatgcttgg atagctttta
    27181 caccgtcagc caagaattta cgtgggtcga agagtttttt cttatcgtat tctgcttcgt
    27241 ttgcttcgta gtcacgagca aatttacgag ttgcgttagc gaatgcgatt tggcattctg
    27301 tgttaacgtt aactttggca acaccaagtt tgatagctgc ttggatttgc tcatcaggaa
    27361 tacctgatcc accgtgcaat acgattggga atcctggaag agcttctgtc aatttttgca
    27421 agtggtcaag gtcaagacct tcccagttta ctgggtaagg gccgtggatg ttaccgatac
    27481 cagctgccaa gaagtcgata ccagtttcaa ccattgcttt agcgtcttcg attggagcca
    27541 attcaccttt accgatgatt ccgtcttctt caccaccgat agtaccaact tcagcttcta
    27601 ctgagatacc tttagcgtgt gctttttcaa caacttcttt agccaattta aggttttctt
    27661 caactggaag gtgtgaaccg tcaaacatga ttgaagtata accaacttcg atacactcaa
    27721 gtgcatcttc gtagtgaccg tggtcaaggt ggatagctac tggtacagtg atacccattg
    27781 attcaacaag gttagcgatc aagttgcgag caactttgta accacccatg tatttagcag
    27841 cacccattga agtttggatc aaaactggag cttttttagc ttctgctgcg cgcaagatag
    27901 cttgagtcca ctcaaggttg tttgtgttaa atccaccaac tgcataaccg ttgtcacggg
    27961 ctgcttggac aaatttttct gctgaaacga ttgccatttt atcaggcctc ctgtatattt
    28021 ttatgggtca tcccatttac attgttcatt ttatcacttt ttgccaaaaa aatctagttt
    28081 ttcccgcagt ttcgattgat tttcttctaa ctccatctat gtaaaccctt tctctcccta
    28141 gtcttggacg acttttggaa aatctataaa gaaggttaaa cgattctcct ccatctcgaa
    28201 acgataagct aatttttcat gttctaatag actcttaacc acaaagagcc ccataccaga
    28261 ccccttgacc ttgcgactag cattgtcaga aaaagactgg gctagttttt cttgttcctc
    28321 tgagctacag ctattttcga taaaaagttc tccttctctt tctccaattc gaactaagcc
    28381 acctggaaca gagtgcttaa tggcattgct gatgagatta gaaagaatca acttcataac
    28441 tgatgggttt agataagcct gctgatgggt caaactattg tctatctgga gctctctttc
    28501 cttggctagc aaggcataat ctttgaccag attttgcgtc atctggagga ggtcaattgt
    28561 ttccctatca tctcgcaatt cctgcacaga agagagggaa agtatctgca gaacatggtg
    28621 attgagttca tccacaatcc ccaaggcaac tcccagatac tggtctctat ccttataacg
    28681 accgatattc tctctcatat tttcgattag gattttcaaa ctagccagcg gtgttttcaa
    28741 ttcatgagaa gctcctcgta ggaattcgac cttcatcttc tccagctgga gaatggcttc
    28801 attcttttca tgcaagtccg caataacagt caagagatgc tggtagaggc tattgatttg
    28861 ttccttgaga ttacctatct catccttaga atccacgcgc aatcgcactt gggaatccag
    28921 gtccatcatc cgacgggtca cccgcttgat ttccaaaatc ggtgcaacaa tagtccgagc
    28981 gtagatgtag gccaccaaga gggaaatcag aaaggaggcc agcaaggtat agggaagaaa
    29041 ctggagactg atttgctctg cttccttttg taaatccatg gaagctagaa actggagaat
    29101 catagtacca ccgtcttgcg ttttcacctc gcgctcctca ataaagagag aggttgtctg
    29161 gcggtctgtg tccagaggaa gactgtcctt gacttctaac ttatcctcgg tcatctcacc
    29221 tttgacggtc cccttgatat cactagtctg ggaatacaag tctaacactt gctcgatact
    29281 ctgcctatct ttcccttcta gggactgggc aatggctgtt gccttttgac caatggtttc
    29341 ctgacgatga ctcagataag tcgaaggaaa aagaaaataa atagctaaat gaaggcagat
    29401 aaccagaaca ctaaatatcg agaaggtata tataaatatc tttgtaaata aacctgttcg
    29461 tttcattttc gctccaattt ataaccaaca ttgcgcacag tgaggataca atccaagtct
    29521 agctttttcc gcaattcctt gatataaaca tcaataacac ggtcaaaggg aacctcatct
    29581 gtcgctttcc agacggcatc gataatctga gaccgagtca aggcccggcc ttcatttttc
    29641 actagatagt ccagaatttc caactctttg gcattgatag gcacttcttg acctgcgagg
    29701 cttgcactgt agctttcaaa gtccaccttg gtatccttgt aagaaaagat tcgtcctgta
    29761 tcgtagtagc gcttgaaaat cgcgtccacc ctcactttta aaagggagag ggagaaaggt
    29821 ttttccagat agccatctgc caaagaggca aaggcactca tcttgtattc ctcatcctga
    29881 aaagctgtca acatcaagac aggaacctga ctggttttac gaatctcagc taggacttct
    29941 aagccgttga gcttgggcat ctggatatcc agtaaaacca gggccacctc atagctagaa
    30001 aattgctcca gagcttcctg accgtccgct gcctcaatag tttcatagcc acaatccgtc
    30061 aaataatcac tgaccccctc acggatcatc tcttcatctt ctacaattaa aattttcata
    30121 ctttaactgc tctctatttt ttatttttct tagaataaat acctactcta ttttctatta
    30181 tagtctcttg ctggcctttt gtctgtaagc aactgaccac tagataaaac gttgtgaaat
    30241 cctttctcat aaattccata actttagtat attatattta agcactaaag tacaaagaaa
    30301 gcaactgaaa gcaatgattt tcaccactgc tttcggattt attttgaatt gttaaatagc
    30361 cattcctatc cactattctt gaatagaaac acaagatgca atctttattc cagactcatt
    30421 ttttcaaatt tattcaccat ccagcaagag ctcttttggt tgttttctaa ggagattgct
    30481 tgaagcaagc gccataacga gaaccactag aaccaaggca aggacaaaaa tgatgataaa
    30541 gtctgatgtc tgaatggaaa tgtctaggct cgacaaggtc ttgctaaagc catctacttc
    30601 tgcaccacca ccaaggttag aggcttgagc cgccttacta gcctgtttgg caacacctga
    30661 agtcacattg gcaaggacag tgtttccaat tgcacgggca gtgtaattag ctaggaagta
    30721 agcagaaact agagcaggga tagcaatcaa gatagattcg gtgatgaatt gacccaagat
    30781 acttgcctgc ttgaggccga tagagaggag aattcccact tccttgcgac gggcgttgat
    30841 ccaaaggctg agcaagaggg caaggaggag aactgagaag ctcaagctac cccagaagag
    30901 gaggttggcc atcttgtaca taccagagat agattgctca agagctgggt agttagagga
    30961 gctcttgacg agtgtgtagc tcttccagtt gataccactg atgccattca actctttcat
    31021 aacatcatcc aagttcttgt ctgctgttac aaagaaggtt gcgtccccat aaatggctgt
    31081 gtcttctgtg tatccataaa gttttgcagc agtgtgaatg tctgtaatag ctgtgttttc
    31141 gtaaagttct tgtgagtagg ttactgctga cttattatga ccatcaaaga gtcccttgat
    31201 tgtcacttca actgtttcct tggctccttt ttcattatct gcatcgtaga tattagagtc
    31261 cagtttaacc ttgtccccta ctttccagcc gtgtttggct gccaagtcct tgtgcaagag
    31321 gattttatcc ttgtcgtcgt tggttaagtg ctctccttcg actagtttat aagaaccaga
    31381 gacaaacttg tcttctttag aggagtcatt gacacctgta atcatcaagc tacttccaaa
    31441 acgcttggca cgatcagcag tgagattctt cttggtttct ggcgtttcaa tcaggtcata
    31501 tccagtcaaa tctccgatag cgttgatacg tttgacataa gactcaatgg ccttgttttc
    31561 ggtgattttt ttgatgtctt cacccttgat attcccagca ccacgaggcg ttccttggtt
    31621 gacgcgacga ttgatttgca tggagaagct attggtgata tttttaaagg tctcctgaga
    31681 agccttggca gtagctccct tgattgacaa gccgaccaaa ctcaagctcg ccatgaggag
    31741 aataatcagg aagatgacaa tcgatttgaa aaacttcctt gtaacatagg caaatgcgtt
    31801 gtgtaacata gattcccttt ctagattttg ttttaatcat tctattaaaa taagctcaaa
    31861 ttatttacta gtattgcgcg tttcagtcag tttcttatcc tttaattcaa gtgtaatatc
    31921 tgacgcttgt gccacttctt tactgtgagt tacgacaatc acacatttac ctgttttctg
    31981 ggcaagtgat ttgagtagtt cgacaatatc tccagcagtt ttaggatcca gatttcctgt
    32041 tggctcatca gctagaataa ctggagcttc tgagaccaaa ctgcgagcaa tggcaacacg
    32101 ttgctgttga ccacctgata actggagaac attccgcttg atctgacttt catccaaacc
    32161 aagctcaaga agtgtatcct tgcttgcctt tttgttgacc aattggatat tttccagcgg
    32221 agaaagataa tctatcaagt tataattttg aaagaccagg gaaatatggt gcatgcgatg
    32281 gtaagaatag cccttcttac gaatatcctc tccttgaaaa aggatagaac cttcaacagg
    32341 actatctaga ccagcaagta gggacaagag tgtggatttt cctgctcctg actccccaat
    32401 aatactgtaa aattttccgg gttcaaaatt ataatcgatc tgatatagga ctgcttcagc
    32461 agtattctta taacggtagg taacatcttg taattgtaat aaagtcatga tttctccttc
    32521 ttaactaata gatgataaaa tttctttcgg tgattttcta aataagaata ggaaacaaag
    32581 ggctacagat aagcaactaa gcagaactag aaaaacatag gattctgcaa aagataagat
    32641 actagttgat aaactgcttg ctttggctag tgtatcttgt aagcttgcct gatctccact
    32701 tgctagtaga gtttggagta ggtaagttgt gattccgttt cctgcaacaa atgctggaag
    32761 caaagctcca agagatacca aaactacctc taaacagaat tgtaggaaga tcgagctctt
    32821 gccttttcca agtgcaagta aaatccccac ttcatagacc cgttctctca accagagaga
    32881 caaaaccaga attaaggctc cagctcctgc tatcaacatc ccataaagga agatggtcag
    32941 gaaggtttgg aaagttgcaa ctgagtcttt gatttgttca aaagccttgt tttccttttc
    33001 gacttggtag ccttgatttt ccaaggccaa gttttctacc tgcttcatga gtccgtccat
    33061 ttccttagga ttttctacat agaagcgtgc tgcactgact tgagcttcac tattgcccaa
    33121 aagggtttgg ctactttcat agtctgtaaa gacttgattt tcactgaagt cagaagacaa
    33181 gcctgtgaat ttctcttgtt ttttaccaga aaagatgcca ataatctcaa actctactgt
    33241 ttgtcctttt ccagattcag actgaccagc atccaagcca atcttgtcat gaagtgaaag
    33301 accgttcttc ttagccaatt cttcgtggat aaggattttc ttggaatccc ctttttgaag
    33361 gtgtcgccct tcttttagat tgaaagccga actggtaaag gttacatcct tggatgaatc
    33421 ctcaagagcc gttaagctaa ccaagttatt gtctgcagct gataaatcat cacgctccac
    33481 gctctgctcg ccagtcactg cttccttgtc ttttagtttt gcgaccgtct caagttcagg
    33541 agagacattt tccagcccct taatcttgct tacagatgct aggtctgaca acttgaatgt
    33601 ctgaccattc tctatcttct taatagaaaa agatgtattg agtgatttat aaagattgct
    33661 ttctactgtt ttgttggact tcatcagagt caaacaggct gaaattccgg ccaataagac
    33721 caataaaatc agaaataaaa taaaacttct cagtcgcttt ctgctgacat aagcccaaga
    33781 tctttggatt ggattcattt gtcacctcca tatttgtaag actattataa aacccaaata
    33841 tgaaatgttt atgaaatacg aaaaaaaa
//
LOCUS       DAVHSL010000020        33805 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000020 DAVHSL010000000
VERSION     DAVHSL010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.020"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            469..1632
                     /locus_tag="VVR39_000963"
     CDS             469..1632
                     /locus_tag="VVR39_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU6030472.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDREVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1629..2306
                     /locus_tag="VVR39_000964"
     CDS             1629..2306
                     /locus_tag="VVR39_000964"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU6030473.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2296..3150
                     /locus_tag="VVR39_000965"
     CDS             2296..3150
                     /locus_tag="VVR39_000965"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU6030474.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3169..4236
                     /locus_tag="VVR39_000966"
     CDS             3169..4236
                     /locus_tag="VVR39_000966"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU6030475.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKKELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            4246..5412
                     /gene="aroC"
                     /locus_tag="VVR39_000967"
     CDS             4246..5412
                     /gene="aroC"
                     /locus_tag="VVR39_000967"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU6030476.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5422..6525
                     /locus_tag="VVR39_000968"
     CDS             5422..6525
                     /locus_tag="VVR39_000968"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU6030477.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6536..6874
                     /locus_tag="VVR39_000969"
     CDS             6536..6874
                     /locus_tag="VVR39_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU6030478.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6966..8249
                     /gene="aroA"
                     /locus_tag="VVR39_000970"
     CDS             6966..8249
                     /gene="aroA"
                     /locus_tag="VVR39_000970"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU6030479.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8242..8718
                     /locus_tag="VVR39_000971"
     CDS             8242..8718
                     /locus_tag="VVR39_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU6030480.1"
                     /translation="MAKVLLGFMGAGKSTIARGLNPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8715..9563
                     /gene="pheA"
                     /locus_tag="VVR39_000972"
     CDS             8715..9563
                     /gene="pheA"
                     /locus_tag="VVR39_000972"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6030481.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9560..10834
                     /gene="psr"
                     /locus_tag="VVR39_000973"
     CDS             9560..10834
                     /gene="psr"
                     /locus_tag="VVR39_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU6030482.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11113..11958
                     /locus_tag="VVR39_000974"
     CDS             11113..11958
                     /locus_tag="VVR39_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6030483.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11948..13051
                     /locus_tag="VVR39_000975"
     CDS             11948..13051
                     /locus_tag="VVR39_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6030484.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKNVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            13053..14039
                     /locus_tag="VVR39_000976"
     CDS             13053..14039
                     /locus_tag="VVR39_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6030485.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            14055..15488
                     /locus_tag="VVR39_000977"
     CDS             14055..15488
                     /locus_tag="VVR39_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU6030486.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15517..16551
                     /locus_tag="VVR39_000978"
     CDS             15517..16551
                     /locus_tag="VVR39_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6030487.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16751..17488
                     /gene="mecA"
                     /locus_tag="VVR39_000979"
     CDS             16751..17488
                     /gene="mecA"
                     /locus_tag="VVR39_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU6030488.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17639..18925
                     /locus_tag="VVR39_000980"
     CDS             17639..18925
                     /locus_tag="VVR39_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU6030489.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVLAELKKVSEFDLLNTFKVLGE"
     gene            18927..19796
                     /locus_tag="VVR39_000981"
     CDS             18927..19796
                     /locus_tag="VVR39_000981"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU6030490.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19872..19949
                     /locus_tag="VVR39_000982"
                     /pseudo
     CDS             19872..19949
                     /locus_tag="VVR39_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            20091..21029
                     /gene="msrB"
                     /locus_tag="VVR39_000983"
     CDS             20091..21029
                     /gene="msrB"
                     /locus_tag="VVR39_000983"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6030491.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            21087..22811
                     /locus_tag="VVR39_000984"
     CDS             21087..22811
                     /locus_tag="VVR39_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030492.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22813..24561
                     /locus_tag="VVR39_000985"
     CDS             22813..24561
                     /locus_tag="VVR39_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030493.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGIIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24863..26122
                     /locus_tag="VVR39_000986"
     CDS             24863..26122
                     /locus_tag="VVR39_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU6030494.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIVDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSNDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26198..26333
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26372..26872
                     /locus_tag="VVR39_000987"
     CDS             26372..26872
                     /locus_tag="VVR39_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU6030495.1"
                     /translation="MSEAIIAKKAELVDVVAGKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26948..27316
                     /gene="rplL"
                     /locus_tag="VVR39_000988"
     CDS             26948..27316
                     /gene="rplL"
                     /locus_tag="VVR39_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU6030496.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27515..27685
                     /locus_tag="VVR39_000989"
     CDS             27515..27685
                     /locus_tag="VVR39_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030497.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27685..27933
                     /locus_tag="VVR39_000990"
                     /pseudo
     CDS             27685..27933
                     /locus_tag="VVR39_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27947..28270
                     /locus_tag="VVR39_000991"
     CDS             27947..28270
                     /locus_tag="VVR39_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030498.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            28263..28643
                     /locus_tag="VVR39_000992"
     CDS             28263..28643
                     /locus_tag="VVR39_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6030499.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLYN"
     gene            28656..28799
                     /locus_tag="VVR39_000993"
     CDS             28656..28799
                     /locus_tag="VVR39_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030500.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            28892..29479
                     /locus_tag="VVR39_000994"
     CDS             28892..29479
                     /locus_tag="VVR39_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6030501.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            29681..29818
                     /locus_tag="VVR39_000995"
     CDS             29681..29818
                     /locus_tag="VVR39_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU6030502.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            30053..31699
                     /locus_tag="VVR39_000996"
     CDS             30053..31699
                     /locus_tag="VVR39_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030503.1"
                     /translation="MYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMN
                     DYPHQFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTS
                     IILITHDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMD
                     KKLHVIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHF
                     FFEDKEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTT
                     IGIVGESGSGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMV
                     FQDPYASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEF
                     SGGQRQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISH
                     DLGVVKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALAT
                     KRKENEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            31709..33118
                     /locus_tag="VVR39_000997"
     CDS             31709..33118
                     /locus_tag="VVR39_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030504.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDTKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            33123..33611
                     /locus_tag="VVR39_000998"
     CDS             33123..33611
                     /locus_tag="VVR39_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEU6030505.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
BASE COUNT        10251 a         6043 c         7428 g        10083 t
ORIGIN      
        1 gtatttttga tagaacatat atttagagtt cgaaatagaa tgatgcaaat aggtgaaatt
       61 ttaattattg ttgcttctat aatattattt attgatagta tattgagttt gtaacaaaag
      121 gcttctctat aaaatcaaat tttccagata cctactgaag ctgatttatt tcttcatctt
      181 tcttctacta cctttgtcac taaatttgac agacacatat tgctgataca acctctctac
      241 ctataatctc acggttaacc tgaggctagt ttcatagttt gctatttgat tttcgttgat
      301 aaaaagaaat gctcctccaa gacggaagag cattttttat tgtgattctt acacatttat
      361 ttcctagttt tgcaggaagt ctagtatacc attttttaaa agaagagtaa aaaagcaagg
      421 gtagtttctt ttttgagaat tgtctaaaag tttgatataa tggtagttat gaatagaata
      481 agagtcagca aaagggttga aaagaagctt gctaaggggc tagttttact agaagccagt
      541 gatcttgaga atgtcaatct taaggatcgg gaagtagagg tgcagggtca ggaaggaaac
      601 tttcttggga ctgcctacct ttctcagcaa aacaagggct tgggctggtt tatcagcaaa
      661 gacaaggtgg ccttcaatca agctttcttt gaaacgttgt ttagaaaagc caaagaaaag
      721 agaaacgcct actatcaaga tgatttgaca actgcctttc gtctctttaa tcaagaggga
      781 gatggctttg ggggtctgac agtggacctt tatggcgact acgccgtctt ttcttggtat
      841 aactcttatg tttatcagat tcgtcagact atatcagaag cctttagaca ggttttccct
      901 gaggttttag gggcttatga gaaaatccgc tttaagggtt tggactatga atctgcccat
      961 gtttatggtc aagaagcacc tgactttttc actgttttag aaaatggtgt cctgtatcaa
     1021 gtctttatga atgatggctt gatgacagga attttcctag accagcatga ggttcgcggt
     1081 agtttagttg acggcttggc tatgggtaaa tccttgctca atatgttttc ctacacagcg
     1141 gctttttcag tagctgcggc catgggagga gctagccaga caacttctgt tgatctagcc
     1201 aaacgttcac gagaattgtc tcaagcgcat tttcaggcaa atgggctcag cacagacgag
     1261 catcgtttta tagtcatgga tgtctttgag tatttcaaat atgccaaacg caaaaacttg
     1321 acctacgatg tgattgtcct agatccgcct agctttgctc ggaataaaaa acaaactttc
     1381 tctgtggcca aggattatca caagttgatt tcccagagtc ttgagatttt aaatccggga
     1441 gggattatca ttgccagtac caatgctgcc aatgtttccc gtcagaaatt tacagaacaa
     1501 attgataaag gctttgcagg aagaagttac cagattttaa acaaatatgg tcttccagca
     1561 gattttgcct ataataaaaa agatgaaagt agtaattacc tcaaggtgat tagtatgaag
     1621 gttagtaaat gaaattaatc gtttcagtaa tgccaagaag tttagaggag gctcaggctc
     1681 tggatgccac gaggtacctg gatgccgaca tcattgaatg gcgtgccgac tatctgccta
     1741 aagaagcgat tttgcaggta gctccagcca tttttgaaaa attcgcaggc cgtgagttgg
     1801 ttttcacgct acgaactcgc tccgaaggtg gagaaatcga cctttctcca gaagagtata
     1861 tccatctaat caaggaagtt gcgcaactct atcaaccaga ctatattgat tttgagtact
     1921 atagctacaa ggatgttttt gaggaaatgc tggacttccc aaatcttgtt ttgagttacc
     1981 ataatttcca agaaacacct gagaacatga tggaaatctt gtcagagttg acgattctaa
     2041 atccaaaact tgttaaggtt gcggtgatgg ctcacacgga gcaggatgtc ttagacttga
     2101 tgaactatac acgaggcttt aaaaccctca atcctgaaca ggaatatgtg accatttcta
     2161 tgggtaaggt gggcaaggtc tctcgtatca ctgcggatgt gactggttcg agttggtctt
     2221 ttgccagtct ggatgaggtt agtgcccctg ggcagatttc tctagctagc atgaaaaaaa
     2281 tcagggagat tttggatgaa gcttgatggc tatacacgtt tagctgcagt tgttgccaat
     2341 cctattaagc attctatttc tcccttcatc cacaatagag cctttgaggc gacagctacc
     2401 aacggtgctt atgtggcttg ggagattgaa gcgagtgact tggtagaaac agtggccaat
     2461 attcgtcgct accagatgtt tggcatcaat ctgtccatgc cctataagga gcaggtgatt
     2521 ccttatttgg ataagctgag cgatgaagcg cgcttgattg gtgcggttaa tacggttgtc
     2581 aatgagaatg gcaatttaat tggatataat acagatggca agggattttt taagtgcttg
     2641 ccttctttta caatttcagg taaaaagatg atcctgctgg gtgcaggtgg tgcggctaaa
     2701 tcaatcttgg cacaggctat tttggatggc gtcagtcaga tttcggtctt tgttcgttcc
     2761 gtttctatgg aaaaaacaag accttaccta gacaagttac aggagcagac aggctttaaa
     2821 gtggatttgt gtgctttaga atatgtttct gaactgcaag caaggattgc cgagtcggat
     2881 ttgctagtta atgccaccag tgtgggcatg gatggccaat tctctcctgt tcctgaaaac
     2941 atagtcttac cagaaactct cttagttgca gatatcatat accaaccctt tgaaacaccg
     3001 tttttgaaat gggctagaag tcagggcaat ccagcagtca atggtctggg aatgttgctc
     3061 tatcaagctg cagaagcttt tcaactatgg acaggcaagg aaatgccgac agaagagatt
     3121 tggcagtctt taacagaaaa ataccaataa agaaagggag actctcctat gaaaatcaga
     3181 atcgatattc ctcatcatcc ttatgatatt cagattgaaa aaggttgtat ggcccaggct
     3241 ggtcagtggt tgcgagaact ctggcaaccg caaaaggtag tcattgtgac agataaccat
     3301 gtagcctctc tctatgcaga gaaggtcaag ctcagcctag aagatgctgg ttttcaggta
     3361 gctgtttttg atttcttaga aggtgaagaa agaaagaatt taactactgt tcagaaagtc
     3421 tatgaatttc tagtcaagca aggtctgact cgtagcgatg gaatcgttgc tcttggtggt
     3481 ggcgttgttg gggacctggc tggctttgta gcctctacct atatgcgggg tattcacttt
     3541 gttcagattc cgactagttt gacagctcag gttgattctt ctatcggtgg aaagacaggc
     3601 gttaacacac catttgctaa aaatatggtg gggacctttg cccaaccaga tggggttctg
     3661 attgatccac ttgttcttga aaccctcgga aaaaaagagt tgattgaagg gatgggtgaa
     3721 gttatcaagt atggcttgat tgaggatcca gaactgtggg ctctcttgac gggactgaat
     3781 ggttctgttg agagtatttt ggaacatgca gagaccttga ttgaacattc ttgtcaggtg
     3841 aagcgcaaga tggtggttga agatgagttg gacaatggta ttcgtcttta cctcaatttt
     3901 ggccacacta ttggccatgc catcgaagcg actgccggtt atggcaaggt catgcatgga
     3961 gaggctgttg ccatgggaat ggtacagatt tccaaggttg ctgaggaaaa aggcctcatg
     4021 ccagctggca ttacccaatc tatcacagag atgtgtcaga aattcggctt gcctgttgac
     4081 tatgaaaatt gggaagttga caagctttat caggctctta ctcatgacaa gaaagcgcgt
     4141 ggtaacacct tgaaattggt cttggtgcca gagcttggtt cagcgatcat tcacccagtt
     4201 tctctggaag agatgaaaga ctacttggta aaataaggag agtgtatgag atatttaact
     4261 gcaggagaat cacacggccc ccgtctaaca gctattattg agggaattcc agctggactt
     4321 ccattgacag ctgaggatat caatgaggac cttagacgcc gtcagggtgg ctacggtcgt
     4381 ggtggtcgta tgaagattga gagtgaccag gttgtcttta cttcgggcgt tcgccacggg
     4441 aagacgacag gggcgcctat tactatggat gtcatcaata aggaccacca gaaatggctg
     4501 gacatcatgt ctgcggagga cattgaagac cgccttaaaa gcaagcggaa aattactcat
     4561 cctcgcccag gtcatgccga tttggttggg gggattaagt accgttttga tgatttgcga
     4621 aattctttgg agcgttcatc agctcgtgaa accaccatgc gggtggcagt tggtgcagta
     4681 gccaaacgcc tcttggctga gctggatatg gagattgcca accatgtcgt ggtctttggt
     4741 ggcaaggaaa tcgatgttcc tgaaaatctg acagtcgctg aaattaagca aagagctgcc
     4801 cagtctgaag tttctattgt taaccaagaa cgagaacagg aaatcaagga ctatattgac
     4861 caaatcaaac gtgatggtga taccatcggt ggggttgtgg agacagtcgt cggaggcgtt
     4921 ccagttggtc ttggttccta tgtccaatgg gatagaaaat tggatgcaag attggctcaa
     4981 gctgttgtct ctatcaatgc ctttaaaggg gtggaatttg gtcttggctt tgaggctggt
     5041 tatcgtaaag gcagccaagt tatggatgaa attctctggt ctaaagaaga cggttatact
     5101 cgccgtacca ataatctagg tggttttgaa ggtggtatga ctaatgggca acccatcgtt
     5161 gttcgtgggg tcatgaaacc cattcctact ctttataaac ctcttatgag tgtggatatc
     5221 gaaacccacg aaccttacaa ggcaaccgtg gagagaagtg atccgactgc tcttccagct
     5281 gcaggaatgg tcatggaagc agttgtagca acggttctgg cgcaagaaat cctcgaaaaa
     5341 ttctcatcag ataatcttga ggaactaaaa gaagcggtag ccaaacaccg agactataca
     5401 aagaactatt aaggagttcc tatggcaaaa acaatctata tcgcaggtct tgggttgatt
     5461 ggagcctcta tggcacttgg tatcaaacgc gatcatccag attatgaaat tttaggttat
     5521 aatcgtagtc aagcttcgag agatatcgcc ttgaaagaag gcatgattga ccgtgcaacg
     5581 gatgattttg ctagttttgc tcctttggca gatgtcatta tcctcagctt gccaatcaaa
     5641 caaactattg ctttcattaa ggagttggcc aatttggatt tgcgagaagg cgttattatt
     5701 tcagatgctg gttcgaccaa gtcaaccatt gtggatgcgg cggagcagta tttggctggc
     5761 aagtctgttc gctttgtcgg ggcccatccc atggctggta gtcacaagac aggggctgct
     5821 tcggcagatg tcaatctttt tgaaaatgcc tattatatct ttacaccttc aagcctgaca
     5881 agtcaggaca cgcttaagga aatgaaggat ctgctttcag gtcttcatgc tcgttttatc
     5941 gagattgatg ccaaggagca tgatcgtgtc acttctcaga ttagccattt tcctcatatt
     6001 ttggcttcta gtctcatgga gcagactgcg gtctatgctc aagagcatga gatggcaagg
     6061 cgctttgcgg caggtggttt tcgagatatg acccgaattg cggaaagcga gccaggaatg
     6121 tggacctcca ttctcttgtc caatagcgag accattctgg atagaattga ggatttcaag
     6181 gaacgtttgg aagtgattgg tcaggccatt agtaagggag atgaagagca aatttggaac
     6241 ttttttaacc aagcgcgtga acaacgccag accatggaaa tccataagcg tggtggtgtg
     6301 gatagctctt acgacctcta tgttgacgtt cctgatgaag aagatgtcat cctgcggatt
     6361 ttggaactgc tacgtggaac ttccttggtt aacatccaca tcaacgagga aaatcgtgag
     6421 gatattcacg gaatcctaca aatttcattt aaaaatgctc aagacttgga aagagctgag
     6481 catctcataa cagaaaatac cgactataca gtcgtcatca aataaggaga agaacatgtc
     6541 aaatatttac gatagtgcaa acgaactcag tcgcggtcta cgcggattac cagaatacaa
     6601 ggctgttaaa gcagctaaag atgcgattgc agcagatgct gaggcaagca aaatctttac
     6661 agaatatctt gcctttcaag aggaaattca aaaactagca catacaggtc aaatgccaga
     6721 tgcgtccttc caagctaaga tggaaggctt tggtaaacag attcaaggaa atagcctctt
     6781 gtcagaattc tttaccaagc aacaacaatt ggccatttac ctttctgaca ttgaaaaaat
     6841 tgtttttgaa ccagtttcag aattgctgaa ataagaaaag aactatccta aagtcaggaa
     6901 tttttaagga atttctggct ttttatgata aaataggtaa aagtattgca agtatgaggt
     6961 ccagtatgaa actaaaaaca aacattcgcc atttacatgg tagtatccgc gtcccaggtg
     7021 acaagtctat cagccaccgt tccattatct ttggaagttt ggctgagggt gagaccaagg
     7081 tttatgatat tctgcgaggt gaagacgttc tttcgaccat gcaggttttt cgtgaccttg
     7141 gtgttgaaat tgaggataaa gatggggtta ttaccattca aggtgtaggc atggctggct
     7201 taaaagcgcc acaaaatgcc cttaatatgg gaaattctgg cacctcgatt cgcctgattt
     7261 caggtgtcct tgctggtgca gatttcgaag tagagatgtt tggagatgat agtctttcca
     7321 aacgtcctat ggaccgtgtg acccttccac tgaaaaaaat gggcgtcagc atttcagggc
     7381 aaactgaacg agacttgcct ccccttcgct taaaagggac gaaaaaccta agacctattc
     7441 attatgagtt gccaattgcc tctgcccaag tcaagtcagc cttgatgttt gcagccttac
     7501 aagctaaggg ggagtcagtt attatcgaaa aagagtgcac ccgtaatcat actgaagata
     7561 tgttgaaaca atttggtggt catttaagtg tggacggtaa gaaaatcaca gtccaagggc
     7621 cacaaaaatt gacaggacag aaggtggtcg taccaggaga tatttccagt gcagcctttt
     7681 ggttagtcgc aggtttgatt gttccaaatt ctcgtctagt gctgcagaat gtggggatca
     7741 acgaaactcg caccggtatt attgatgtca ttcgtgccat gggtggaaaa ttggaaataa
     7801 ctgaaatcga tccagtcgct aaatcttcta ccttgactgt tgagtcttct gacttgaaag
     7861 gaacagagat tggtggcgct ttgattccac gattgattga tgaattgccc attattgccc
     7921 tgcttgcgac tcaagcccaa ggtgtaacag ttatcaagga tgctgaggag ctcaaggtca
     7981 aggaaacaga ccgtattcag gttgtggcag acgccttaaa tagtatggga gcagatatta
     8041 ctcctacggc agatgggatg attatcaaag ggaaatcagc tcttcacggt gctagagtca
     8101 atacgtttgg tgaccaccgt atcggcatga tgacagctat cgcagccctc ttggttgcag
     8161 atggagaggt ggagcttgac cgtgcagaag ccatcaatac cagctatcct agtttctttg
     8221 atgatttgga gagcttgatt catggctaag gtgttattag ggtttatggg ggctggaaaa
     8281 tcgactattg caagaggctt gaaccctaat taccttgata tggatgctct gattgagaag
     8341 cgcctaggta tgtccattgc gaattttttc gctgaaaagg gagaagcagc ctttcgtcag
     8401 gtagaatcag aagtcctagc tgatttacta caaacagacc aagtcgtgtc aactggagga
     8461 ggagtggtta tttctcagag aaatcgtgac ttactcaaga ctaatacaga taacatctac
     8521 ctgaaagcag attttgaaac cctctaccaa cgtatcgcag ctgataagga caatcagcga
     8581 ccgctttttc taaataatag caaggaagaa ctagtagcta tttttcaaga aagacaggct
     8641 tggtatgagg aagtggctag tcgggttttg gatgtgacca agctaagccc agaggaaatt
     8701 atagaggaac taagatgaaa attgcttatc taggtcccaa gggatcattt tcacaccacg
     8761 ttgtgcagat agcttttcct catgaggaat tgcaggcttt tgccaacatt acagatgtca
     8821 tcaaggctta tgagcaagga ttagtggact attctgtggt gccagttgaa aattctattg
     8881 agggtagtgt tcatgaaacc ttggactatc tttttcatca ggctcacatc caagcagtag
     8941 cagaaatcgt tcagcctatt catcagcagt tgatggtggt tccaggccat actaagattg
     9001 aaaagatttt ttcacatcca caggccttgg ctcaaggaaa gaaattcatc gatgaacaat
     9061 atccagaggc tcaaatcgag gtaacagcta gtacagctta tgcggcccgt tttatttccg
     9121 aacatccaga tcagcccttt gcagcagttg cacctagaag ttctgctgaa gaatatggat
     9181 tggaactgat tgccgaggat attcaggaaa tggaagccaa tttcacacgt ttctggcttc
     9241 taggagctga aaagcctagt attcccttgc aagcacaaac tgaaaagatg agtttggcct
     9301 tgacattacc tgacaacctt ccaggtgcac tttataaggc cctgtcgacc tttgcttggc
     9361 gaggaattga cttgacaaaa attgaaagtc gtccactcaa gacagcactg ggtgaatact
     9421 ttttcattat cgatgtggat tataccgata aggacttggt ccactttgcc caaaaagaat
     9481 tagaagcgat tggaatccag tataaaattc tgggtgccta tcctatttat ccaatatcag
     9541 accatggaaa ggagagaaga tgagtaaaga aaatccctta agtcatcatg agcagttgcg
     9601 ttatgattat ttgctaaaaa atattcacta tctcaatgag agagaaaaaa atgagtttgc
     9661 ctatttgcaa gaaaagctaa ctcttgctag gggaaatagt agctctagct tggaacaaga
     9721 aagagaagag caggttgact taccaagcta tgcgaaccgg agtcgctcac aatccaaatc
     9781 acaagcactc tctttccctc caaaaaagaa aagacggaag ctccgtctta aacgaatttt
     9841 tatggtgatt ttttcacttt tggtctgtgt ggctttggcc atggtattca tgtttttgcg
     9901 tggttaccaa gatgctagcg caaagaaaac tgctgatgcc cgggcagctc aagtagaagt
     9961 ctttaatggt caggacacta gagatggagt taatatttta atcatgggta ctgatggtcg
    10021 aatcggccag aacagtgttg agacacgaac tgactctatt atggtattaa atgtcggggg
    10081 ctcagataag aaaatgaagc tagtcagttt catgcgtgat aatttggtct atatagatgg
    10141 ttatagtcaa gtgattaatg gtagaaaaca gacagataac aagttaaacg tagcctacga
    10201 gttaggagaa caagaggggc aaaaaggggc agaaatggtt cgccaagtct tgaaagataa
    10261 ttttgacttg gacattaagt actacgcctt ggttgatttc caggcctttg ccacagcgat
    10321 tgacacgctt ttccctgatg gggtgacgat tgatgctcaa ttttcaacat tgaatgggcg
    10381 tcccctaaca gaagctacag tcggagatga tttatatgct accgagactg agtctccaac
    10441 ccaaaccatt aaagtcggaa aacagcagat gaatggctcg accctgctca attatgctcg
    10501 tttccgtgat gatgatgagg cggattacgg ccgtacaaaa agacagcaac aagttttaac
    10561 agcaatttta gagcaaatta aagatcccac taaacttttc actggttctg aagctcttgg
    10621 aaaggttttt gctatgacct caaccaacgt accctatact ttcctcctaa caaacggttt
    10681 atctgttttg gatggagcaa aaaatggtat tgaaaaattg acgattccag aactgggtga
    10741 ctgggtagat gcctatgatg tttatggagg cttgggcttg ctggttgatc aaaacaaata
    10801 tcaaaccaag ctcgctcaaa tgggcttgag ataagataat actcaatgaa aatcaaagtg
    10861 caaactagga agctagccgc aggctgctaa aaacacagtt ttgaggttat agataagact
    10921 gacgaagtca gttacctata cctacggcaa ggtaaagctg acgtgctttg aagagatttt
    10981 cgaagagtat aagacagaaa aatcaaagtt tgatagctat ttggatagca gtcaggcttt
    11041 gattttttac agtctgcaat agattttcac cccttgtttg tggtataatg aaacgatacg
    11101 atagaaagaa taatgaacaa tatgactgat ttaaaagcaa ttcaggctcg tagtctggag
    11161 atggctgaat attttgtggc cttttgtaaa gaacatgatt tgctctgtta tctctgtggc
    11221 ggaggcgcta ttggtgccct tcgaaacaag ggatttattc cttgggacga cgacctagac
    11281 ttttttatgc ctcgtaaaga ttatgagaaa ttagcagaat tatggcctcg ttatgcagat
    11341 gaacgttatt tcttgtcaaa gagtcacaag aattttgttg atcgtaatct ttttattacc
    11401 attcgtgaca aggaaaccac ctgtatcaag ccttatcagc aggatttgga tttgccacat
    11461 ggtctggcct tggatgtttt gcctttggat tattatccga aaaatccagc tgagcggaaa
    11521 aaacaggttc gttgggcctt gatttattca ctcttttgtg cgcaaactat tccagaaaag
    11581 catggtgctc tcatgaaatg gggaagtcgc attttactgg gtttgactcc aaaatctctc
    11641 cgttatcgca tctggaaaaa agctgagaaa gaaatgacta agtatgattt ggctgattgt
    11701 gatggcatta cagaattatg ctcaggtcct ggctacatga gaaacaagta cccaatcaca
    11761 tcttttgaag acaatctttt cttgccattt gaaggaacag agatgcctat tccaatcggc
    11821 tatgatgtct atctcagaac tgcttttggg gattatatga cgcctccacc agcagacaag
    11881 caggtaccgc atcatgatgc tgtcatcgct gatatggata agtcttatac agaatacaag
    11941 ggagaatatg gtggctaaga aaaaaatctt attttttatg tggtcttttt ctcttggagg
    12001 tggtgcagag aagattctat caaccattgt ttcaaatctg gatccagaaa agtatgatat
    12061 tgatattctt gaaatggagc actttgacaa gggatatgaa tctgttccaa agaatgtacg
    12121 cattttaaaa tcccttcaag attatcgcca aaccagatgg ttacgagctt ttttgtggag
    12181 aatgagaatt tattttccaa gactgactcg tcgtttgctt gtaaaagatg attatgatgt
    12241 tgaagtttct tttaccatta tgaatccacc actgttgttc tctaaaagaa gagaagtcaa
    12301 gaagatatct tggattcatg gaagtattga agaacttctt aaggatagct ctaaaagaga
    12361 atcacataga agccagttgg atgctgcgaa tacaattgta gggatttcaa aaaagaccag
    12421 caattctatc aaggaagttt atccagatta tgcttctaaa ttacagacaa tctacaatgg
    12481 atatgatttt cagactattc tagaaaaatc tcaagagaag atcgatatcg agattgctcc
    12541 tcaaagtatc tgtactatcg gacggattga ggaaaataag ggttctgacc gtgtagtgga
    12601 agtgatacga ttattacacc aagagggaaa aaactatcat ctctatttta tcggggctgg
    12661 tgatatggaa gaggaactga aaaaacgagt caaagagtat gagattgagg actatgtaca
    12721 tttccttggt tatcaaaaaa atccttatca gtatttatct cagacgaaag ttctcttgtc
    12781 tatgtctaaa caagaaggtt ttcctggagt gtatgtggag gccttgagtc tgggactccc
    12841 ttttatctct acggacgttg gaggggctga ggaattatcc caagaaggac gatttggaca
    12901 aatcattgag agcaatcaag aggcagctca ggcgattact aattacatga cttctgcctc
    12961 aaactttgat gtcgatgagg ctagccaatt cattcaacaa tttacaatta caaaacaaat
    13021 cgaacaagta gaaaaactat tagaggagta gcatggaaac tgcattaatt agtgtgattg
    13081 tgccagtcta taatgtggcg cagtacctag aaaaatcgat agcttccatt cagaagcaga
    13141 cctatcaaaa tctggaaatt attcttgttg atgatggtgc aacagatgaa agtggtcgct
    13201 tgtgtgattc aatcgctgaa caagatgaca gggtgtcagt gcttcataaa aagaacgaag
    13261 gattgtcgca agcacgaaat gatgggatga agcaggctca cggggattat ctgattttta
    13321 ttgactcaga tgattatatc catccagaaa tgattcagag cttatatgag caattagttc
    13381 aagaagatgc ggatgtttcg agctgtggtg tcatgaatgt ctatgctaat gatgaaagcc
    13441 cacagtcagc caatcaggat gactattttg tctgtgattc tcaaacattt ctaaaggaat
    13501 acctcatagg tgaaaaaata cctgggacga tttgcaataa gctaatcaag agacagattg
    13561 caactgacct atcctttcct aaggggttga tttacgaaga tgcctattac cattttgatt
    13621 taatcaagtt ggccaagaag tatgtggtta atactaaacc ctattattac tatttccata
    13681 gaggggatag tattacgacc aaaccctatg cagagaagga tttagcctat attgatatct
    13741 accaaaagtt ttataatgaa gttgtgaaaa actatcctga cttgaaagag gtcgcttttt
    13801 tcagattggc ctatgcccac ttctttattc tggataagat gttgctagat gatcagtata
    13861 aacagtttga agcctattct cagattcatc gttttttaaa aggccatgcc tttgctattt
    13921 ctaggaatcc aattttccgt aaggggagaa gaattagtgc tttggcccta ttcataaata
    13981 tttccttata ccgattctta ttactgaaaa atattgaaaa atctaaaaaa ttacattaga
    14041 acgggggtga ccaagtgatt gatgggaaac gattattatt tagtttgacc atagtcagtt
    14101 atgccttgac gctagtaagt ggaattgtgt atctgtttaa taataataat gttagcttac
    14161 tttctacttt attgttcttg ttggttagta gcttgattgc ttgttggaat gatatcaagt
    14221 attacttaat ccattttatt ttctatttaa ccatttttgt atttctggta tcaagaccga
    14281 ccattgatta ttttagggat ggtgctttgg atacctatca tccaatagcc tatcgttttg
    14341 cctttatagt tgtcatggtt tcgattctgg gcttgacaac aggaggcgtc ctggctcgtt
    14401 acttcatagc taggaagaaa ataaaagtag caaatatagg aaattctcta aaagaggttt
    14461 atatcaagcg gttacgcttt gtatcactag gagtttttct tctaacttat cctttctatt
    14521 tcattcggtt atttgaacgg ctcttgtatc gtttgcagac ttcctactat gcctactatg
    14581 caaattttga aagtaaactg ccttatttta cctacatttt gtctaccttt acggtctatg
    14641 caatgtgtat gtatctggca accaagccaa agaaattgca ggccacagca gtgcttgtct
    14701 cctttattgc agctaacact attcatttgg caattgggac acgaaatccc tttattttaa
    14761 gtattttatt tgcttttgtt tattacttta tgcgggagca agctgaaaaa ggaaaatgga
    14821 ttgggtttaa agaaaagtta gcgatttttg taggttctcc tattctcatg ttagcgatgg
    14881 gagtactcaa ttatgtacgg gataatgtcc aagtttccca tacaggtttc tgggatatct
    14941 tacttgactt tatctataaa caagggacta gttttggtgt tctggctcga ggttttctat
    15001 ttaacagtag cctcccttac cgagatttcc gtaattttac ttttggtcct gttcttgatt
    15061 attttgcaag ggggagtttg ggagccattt tcggaggaaa agcctttgaa catacaacca
    15121 atagtgtgga actagctatt gatagtaata gttatgccca caatctatcc tatcttgtct
    15181 tgaacaagga atacttgaaa gggcatggta tcggaagtag ttatatcatg gagttgtata
    15241 ccgactatgg tatgattgga gtctttctgc ttagtttctt actcggcgta ttatttatag
    15301 ccatgctgca agtagcctat cgctcaagga caatcctatt tgctttatcc ctactcatct
    15361 tgaataatct attctttatg ccaagaagca gcttttcaga aagtttcttc aatttattta
    15421 caatgcaatt ctggggaatt gttcttgtga ttatatttgt agcaaaaatg cttacaaagg
    15481 aaaactagta tctactaaac aaaggagaaa aaaatcatgt ttgaacatta ttcagtagct
    15541 gatttgtttg caaatcttta taaaaagcga aaagcaaata ttttagctct catcgcttta
    15601 tttgctctca ttgctgtacc atttacaatt aaagcagtta ggaataaaaa cactgtcaaa
    15661 gatacaacaa gttattcaac ttatcttatc tataaaatca ctcctccaga agagtcggcc
    15721 aaaacgattt tgaatcatca aattggtggt tatagtgatt tttatgggaa attgattgat
    15781 ggtaatttga atggagctta tcttttcaat gatgtagaac ccagtgagtt gaaaaaaatt
    15841 gccagtgaat tagacacgac agaaacaacc ttgaaaaatt caacgaatga ctattggtgg
    15901 aaaaaattga ccgtctacta tatgattgac gatgcagggg ttggtgtgaa aattttgaca
    15961 tcaagtaaag atgccaatga cttgttagag aaaaaaattg atgggttgat tgagaaattt
    16021 aaacatgcct atgcaaatgt gaaaattgaa aaactggaaa ccatcaactc taaagaattg
    16081 aacgcaaatg gtgaaacagc gcttggctta aatgtgaaaa atctgattct tcgtttagtt
    16141 gttattggag tggtttgtgt gattttggtt gtgatgggaa atgtgttagt ttatctcttt
    16201 aatccaacaa tcaatagagt aggtgatttt tctcagtatc aaattgattt tgtaacagag
    16261 attacaacaa ttgctaacct agcagatgtt ttgtcataca aaaatactgg acaggaattg
    16321 accatcgtta gctcaaataa agctatccta gataaattga aacagagtca agaagcttta
    16381 aaaggaatgc attttgtaga tttacaggat gtatcatctc ttttggaaag agatacagtc
    16441 cttcttgttg aagagtacgg agtgactcgt tataagaaat ttgagcaaag tcttcaaatt
    16501 ctcagaaact taaatcgttc tatccttggt gtagcaacct ttaaattata agtattctga
    16561 tgtataaggt cttcaaaatc ggctaagagc tgattttgaa ggctttttct atctgtctgc
    16621 agaaattttc ttttggagtc tcctatagaa agaccctagg gaaaatctat ccgtatagag
    16681 gagccttctt ttgataaaat cgtaaaaatc tagtataata gatagaactg aaagtatgag
    16741 gttactagca atgaaaatga aacaaattag tgatacaact ttaaaaatca cgatgtcttt
    16801 agaggatttg atggatcgtg gaatggagat tgctgacttt ctcgttcctc aagaaaaaac
    16861 agaagagttc ttttatgcta tcttggatga gctagagatg cctgatagct ttctggatac
    16921 aggcatgttg agcttccgtg tgactccaaa acctgataag gtagatgtct ttgtgaccaa
    16981 gtcaaagatt gaccaaaatc tagattttga agacttatcg gatttgccag atatggaaga
    17041 attggctcaa atgtctccag atgaatttat caaaaccctg gaaaaaagca tcgcagacaa
    17101 aaccaaggat gatatcgaag ccattcaatc tcttgagcaa gttgaagcca aggaagaaga
    17161 gcaagagcag gctgaacaag aagctgagag taagaaagaa ccttacatct actacatcct
    17221 ttcttttgct aagttggctg acttggtagt ttttgccaag acagtgactt ttgaaatgga
    17281 aacttctgaa ctctacaaaa tgaacgagcg ctattatttg accattttag tggatattga
    17341 aaatcatcca agcccatatc cagcttggct gttggcccgt atgcgcgagt ttgcagacga
    17401 tagtgatatc agtcgctcag tcttacaaga gtatggtcaa gtcttgatga gtcacgatgc
    17461 agtgctcaat ctgcaaaaaa tcggctaatc ctttctggaa agctattttc agattttaag
    17521 aagagcgaat cgtctgattc gttttttctt tttatactga aatagtgatt tactataata
    17581 ggaattttca caaaattctg ttataatggc tatattagaa aatttcgagg agataaagat
    17641 gacagttaaa attgctttac taggatttgg taccgttgca agtggtgtgc ctttcctcct
    17701 aaaggaaaat ggaggaaaaa tcaatcaatc agcacattca gatatcaaag ttgctaaggt
    17761 attggtcaag gatgaagatg aaaaaaatcg cttgcttgca gcagggaatg actttaactt
    17821 tgtaaccaat gtggatgata ttttatcaga ccaggatatt actatcgtag tggaattgat
    17881 ggggcgtatt gagcctgcta aaacctttat cactcgtgcc ttggaagctg gaaaacacgt
    17941 tgttactgct aacaaggacc ttttagctgt ccatggcgca gaattgctag aaatcgctca
    18001 agctaacaag gtagcacttt actacgaagc agcagttgct ggtgggattc caattcttcg
    18061 tactttagca aattccttgg cttctgataa aattacgcgc gtgcttggag tagtcaacgg
    18121 aacttccaac ttcatggtga ccaagatggt ggaagaaggc tggtcttacg atgatgctct
    18181 tgcggaagca caacgtctag gatttgcaga aagcgatccg acgaatgacg tagatgggat
    18241 tgatgcagcc tacaagatgg ttattttgag ccaatttgcc tttggcatga agattgcctt
    18301 tgatgatgta gcccacaagg gaatccgcaa tatcacacca gaagacgtag ctgtagctca
    18361 agagcttggt tacgtagtga aattggttgg ttctattgag gaaacttctt caggtattgc
    18421 tgcagaagtg actccaacct tcctacctaa agcgcaccca cttgctagtg tgaatggcgt
    18481 aatgaacgct gtctttgtag aatctatcgg tattggtgag tctatgtact acggaccagg
    18541 tgctggtcaa aaaccaactg caacaagtgt tgtagctgat attgtccgta tcgttcgtcg
    18601 tttgaatgat ggtactattg gcaaagactt caacgaatat agccgtgact tggtcttggc
    18661 aaatcctgaa gatgtcaaag caaactacta tttctcaatc ttggctctag actcaaaagg
    18721 tcaggtcttg aagttggctg aaatcttcaa tgctcaagat atttccttta agcaaatcct
    18781 tcaagatggc aaagagggtg acaaggcgcg tgtcgttatc atcacacaca agattaataa
    18841 agcccagctt gaaaatgtct tagctgaatt gaagaaggtt tcagaattcg acctcttgaa
    18901 taccttcaag gtgctaggag aataagatga agattattgt acctgcaacc agtgccaata
    18961 tcgggccagg ttttgactcg gtcggtgtag ctgtaaccaa gtatcttcaa attgaggtct
    19021 gcgaagaacg agatgagtgg ctgattgaac accagattgg caaatggatt ccacatgatg
    19081 agcgtaatct cttgctcaaa atcgctttgc aaattgtacc agacttgcaa ccaagacgct
    19141 tgaaaatgac cagtgatgtc cctttggcgc gcggtttggg ttcttccagc tcggttatcg
    19201 ttgctgggat tgaactagcc aaccaactgg gtcaactcaa cttatcagac catgaaaaat
    19261 tgcagttagc gaccaagatt gaagggcatc ctgacaatgt ggctccagcc atttatggta
    19321 atctcgttat tgcaagttct gttgaagggc aagtctctgc tatcgtagca gactttccag
    19381 agtgtgattt tctagcttac attccaaact atgaattacg tactcgagac agccgtagtg
    19441 tcttgcctaa aaaattgtct tataaggaag ctgttgctgc aagttctatc gccaatgtag
    19501 cggttgctgc cttgttggca ggagacatgg tgaccgctgg gcaagcaatc gagggagacc
    19561 tcttccatga gcgctatcgt caggacttgg taagagaatt tgcgatgatt aagcaagtga
    19621 ccaaagaaaa tggggcctat gcaacctacc tttctggtgc tgggccgaca gttatggttc
    19681 tggcttctca tgacaagatg ccaacaatta aggcagaatt ggaaaagcaa cctttcaaag
    19741 gaaaactgca tgacttgaga gttgataccc aaggtgtccg tgtagaagca aaataaagaa
    19801 tagaagatag gatggggaaa ctcttgacca gagggtttca tatccttttt gtgaaaagaa
    19861 gtttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac
    19921 agtgttttga ggttgtggat agaactgacg aagtcagctc aagacactgt tttgaggttg
    19981 cagatagaac tgacgaagtc agtaacatat atacggtaag gtgacgctga cgtggtttga
    20041 agagattttc gaagagtatt agttaaaaac gtgataaagg agaaataaag atggcagaaa
    20101 tttatctagc aggtggttgt ttttggggcc tagaggaata tttttcacgc atttctggag
    20161 tgctagaaac cagtgttggc tacgctaatg gtcaagtcga aacgaccaat taccagttga
    20221 tcaaggaaac agaccatgca gaaacggtcc aagtgattta cgatgagaag gaagtgtcac
    20281 tcagagagat tttactttat tatttccgag ttatcgatcc tctatctatc aatcaacaag
    20341 ggaatgaccg tggtcgccaa tatcgaactg ggatttatta tcaggatgaa gcagatttgc
    20401 cagctatcta cacagtggta caggagcagg aacgcatgct gggtcgaaag attgcagtag
    20461 aagtggagca attacgccac tacattctgg ctgaagacta ccaccaagac tatctcagga
    20521 agaatccttc aggttactgt catatcgatg tgaccgatgc tgataagcca ttgattgatg
    20581 cagcaaacta tgaaaagcct agtcaagagg tgttgaaggc cagtctatct gaagagtctt
    20641 atcgtgtcac acaagaagct gctacagagg ctccatttac caatgcctat gaccaaacct
    20701 ttgaagaggg gatttatgta gatattacga caggtgagcc actctttttt gccaaggata
    20761 agtttgcttc aggttgtggt tggccaagtt ttagccgtcc gatttccaaa gagttgattc
    20821 attattacaa ggatctgagc catggaatgg agcgaattga agttcgttct cgttcaggca
    20881 gtgctcactt gggtcatgtt ttcacagatg gaccgcggga gttaggcggc ctccgttact
    20941 gtatcaattc tgcttcttta cgctttgtgg ccaaggatga gatggaaaaa gcaggatatg
    21001 gctatctatt gccttactta aacaaataaa acagagagtg gggcttccca ctttcttcat
    21061 ttctagaata tgaatagaag ggatttatga aacacctatt atcttacttc aaaccctaca
    21121 tcaaggaatc aattttagcc cccttgttca agctgttaga agctgttttt gagctcttgg
    21181 ttcccatggt gattgctggg attgttgacc aatctttacc tcagggagat caaggtcatc
    21241 tctggatgca gattggcctg ctccttatct ttgcagtaat tggcgtttta gtggccttga
    21301 tagctcaatt ttactcagca aaggcagcag taggttttgc taaggaattg acaaacgatc
    21361 tttatcgtca tattctttcc ttgcccaagg acagcagaga ccgtctgaca acatctagtt
    21421 tggtcactcg cttgacttcg gatacttacc agattcagac tggtatcaat caattcctgc
    21481 gtctcttttt gcgagcgccc attatcgttt ttggtgccat ttttatggct tatcgaatct
    21541 caactgagtt gactttctgg ttcttagtca tggttgccat tttgaccatt gtcattgtag
    21601 ggttatctcg attggtcaat cctctctaca gtagtctcag aaagaaaacg gaccaactgg
    21661 ttcaggaaac gcgccagcaa ttgcaaggga tgcgggttat tcgtgctttt ggtcaagaaa
    21721 aacgagagtt acagattttt caaaccctta accaagttta tgctagatta caagaaaaga
    21781 caggtttctg gtctagttta ttaacacctc tgacctatct gattgtcaat ggaactcttc
    21841 tcgttattat ctggcaaggc tatatttcaa ttcaaggagg agtgctcagt caaggtgctc
    21901 tcattgctct tatcaattac ctcttacaga ttttggtgga attggtcaag ctagccatgt
    21961 tgataaattc tctcaaccag tcctatatct cagccaagcg aatcgaggaa gtctttgttg
    22021 aggctccaga ggatatccat tcagagttag aacaaaagca agctaccaga gataaggttt
    22081 tacaagtcca agaattgacc tttacctatc ctgatgcggc ccagccttct ctgagataca
    22141 tttcctttga tatgactcaa ggacaaattc taggtatcat cgggggaact ggttctggta
    22201 aatcaagctt ggtgcaactc ttacttggac tttatccagt agacaagggg aacattgacc
    22261 tttatcaaaa tggacgtagt cctcttaatt tggagcagtg gcggtcttgg attgcctatg
    22321 tacctcaaaa ggtcgaactc tttaagggaa ctattcgttc caacttgact ttaggtttaa
    22381 atcaagaagt gactgatcaa gaactctggc aagccttgga aattgctcaa gctaaggatt
    22441 ttgtcagtga taaggaagga ctcttggatg ctctagttga agcaggaggg cgaaatttct
    22501 caggtggaca aaaacaaagg ctgtctatcg cacgagcagt cttgcgccag gctccgtttc
    22561 tcatcctaga tgatgcgacc tcagcactgg acaccattac agagtccaag ctcttgaaag
    22621 ctattagaga aaattttcca aacatgagct taattttgat ctctcaacga acctcgactt
    22681 tacagatggc ggaccagatt ctcctcttgg aaaaaggtga gttgctagct gttggcaagc
    22741 acgatgactt gatgaaatcc agtcaagtct atcgtgaaat caatgcatcc caacatggaa
    22801 aggaggacta gaatgaaacg acaaactgta aaccagacgc tcaaacgttt agtcgtagat
    22861 ttggcaaacc atcccttcct ccttttccta gcctttctag gaactattgc ccaagttggc
    22921 ttatcaattt acctacctat tctgattggg caggtcattg accaagtcct agtggctggt
    22981 tcatcaccag ttttttggca gatttttctc cagatgctct tggtagtaat aggaaatact
    23041 ctggtacaat gggccaatcc tctcctctat aatcgtctaa tcttctctta taccagagat
    23101 ttacgagagc gaatcatcca taaactccat cggttaccga ttgcttttgc ggatcggcaa
    23161 ggcaatggag agatggtcag tcgtgtaacc acggatatcg aacagttggc agctggcttg
    23221 accatgattt ttaaccaatt tttcattggt gttttgatga ttttggttag tattctagcc
    23281 atgctccaaa ttcatctcct catgactctc ttagtcttgc tgttgacgcc actgtccatg
    23341 gtgatttcac gctttattgc caagagatcc tatcatctct tccagaagca aacagagacg
    23401 aggggaattc agactcagtt gattgaagaa tcgcttagcc agcagactat aatccagtcc
    23461 ttcaatgctc aaacagaatt tatccaaaga ttgcgtgagg ctcatgacaa ctactcaggc
    23521 tattctcagt cagccatctt ttattcttca acggtcaatc cttcgactcg ctttgtaaat
    23581 gcactcattt atgccctttt agctggagta ggagcttatc gtatcatgat gggttcaacc
    23641 ttgactgtcg gtcgtttagt gacttttttg aactatgttc agcaatacac caagcccttt
    23701 aacgatattt cttcagtgct agctgagttg caaagtgctc tggcttgcgt agagcgtatc
    23761 tatggagtct tagatagccc tgaagtggct gaaacaggta aggaagtctt gaccagtgac
    23821 caagttaagg gagctatttc ctttaaacat gtctcttttg gctaccatcc tgaaaaaatt
    23881 ttgattaagg acttgtctat cgatattcca gctggtagta aggtagccat cgttggtccg
    23941 acaggtgctg gaaaatcaac tcttatcaat ctccttatgc gtttttatcc cattagctcg
    24001 ggagatatct tgctggatgg gcaatccatt tatgattata cacgagtatc attgagacag
    24061 cagtttggta tggtgcttca agaaacctgg ctcacacaag ggatcattca tgataatatt
    24121 gcctttggca atcctgaagc cagtcgagag caagtaattg ctgctgccaa agcagctaat
    24181 gcagactttt tcattcaaca gttgccacag ggatacgata ccaagttgga aaatgctgga
    24241 gaatctctct ctgtcggcca agctcagctc ttgaccatag cccgagtctt tctggctatt
    24301 ccaaagattc ttatcttaga cgaggcaact tcttccattg atacacggac agaagtgctg
    24361 gtacaggatg cctttgcaaa actcatgaag ggccgcacaa gcttcatcat tgctcaccgt
    24421 ttgtcaacca ttcaggatgc ggatttaatt cttgtcttag tagatggtga tattgttgaa
    24481 tatggtaacc atcaagaact catggataga aagggtaagt attaccaaat gcaaaaagct
    24541 gcggctttta gttctgaata agccattctc ttttgaaagt ttatggacga aaaaagttgc
    24601 cttcgagtga cttttttgtt acaatagcta gaaaaattgt tcactgtaat actcaatgaa
    24661 aatcaaagag caaactagga agctagccgt aggttgctca aagcacagct ttgaggttgt
    24721 agataagact gacgaagtca gttcaaaaca ctgttttgag gttgcagata gaactgacga
    24781 agtcagtaac cacacctacg gcaaagtgaa tctgaagtgg tttgaagaga gtacaacttg
    24841 tcttttagaa aaggagccta taatgaaagt ctttcagcat gtaaatatcg tgacttgtga
    24901 tcaaaatttc catgtttatc ttgatggaat cttagcagtc aaggattctc aaatcgtcta
    24961 tgtcggtcaa gataagccag cgtttttaga acaagctgag cagattgtag actatcaggg
    25021 agcttggatt atgcctggtt tggtcaattg tcacacccat tctgcaatga caggtctgag
    25081 agggatccga gatgacagca atctccatga atggctcaat gactatatct ggccagcaga
    25141 atctgagttt actcccgaca tgactaccaa tgcggtcaaa gaagccctga cagagatgct
    25201 ccagtcagga acaacaacct ttaacgatat gtataatccc aatggtgtgg atattcagca
    25261 aatttatcag gtggtgaaaa cttccaagat gcgttgttat ttttctccga ctctcttttc
    25321 ttcagagaca gaaacaactg ctgagactat aagcagaact cgatccatca tagacgaaat
    25381 cttaaaatat aaaaatccaa atttcaaggt tatggtagca cctcattctc cgtatagctg
    25441 cagtagagac ttgctggaag cgagtttgga aatggcaaaa gagctaaata ttccgctcca
    25501 tgtccatgtg gcggagacca aggaggagtc aggaattatc ctcaaacgat acggcaaacg
    25561 cccccttgct tttcttgaag aactgggtta tttagatcat ccgtccgtat ttgctcacgg
    25621 ggtcgaatta aacgagagag aaattgaacg cttggcatct tctcaagtgg ctatcgccca
    25681 caatcctatc agtaacctca aactggcatc aggaattgct ccaattatcc agctccaaaa
    25741 agcgggagta gcagtcggaa ttgcgactga ctcggttgct tccaataaca atctagatat
    25801 gtttgaggaa ggaaggactg cagctcttct tcagaagatg aaaagtgggg atgccagcca
    25861 gtttccaatc gaaacagctc tcaaggtact gacaatcgaa ggggctaagg cccttggaat
    25921 ggaaaatcag ataggaagtc tggaagtcgg caagcaagca gattttctgg tcattcaacc
    25981 acaagggaaa attcatctcc aacctcagga aaatatgctg tctcacctgg tttatgcagt
    26041 taaatctaat gatgtagatg atgtttatat cgccggagaa caggttgtta agcaaggtca
    26101 agtcctgaca gtagaacttt aaaagaaaaa tcacgaaaaa ttttaaaaaa agtttgcaaa
    26161 aatcttgcat tctttttttg actatgctat acttatatac ggtttaaaaa aactgcctaa
    26221 gacagtaggg gagctcgact cataaatatc ctaccgagga caagacgtat catgtaaaaa
    26281 gaagcgtatt gtactttcgt gtctaggttt gggcgcgttt ttctttttga aaaattcccc
    26341 aagcaaaata attacggagg tgaacacact aatgagtgaa gcaattattg ctaaaaaagc
    26401 ggaactagtt gacgtagtag ctggaaaaat gaaagctgct gcatctatcg tcgttgtaga
    26461 cgctcgtggt ttgacagttg agcaagatac agttcttcgt cgtgagcttc gtggaagcga
    26521 agttgagtat aaagttatta aaaactcaat cttgcgtcgt gcagctgaaa aagctggtct
    26581 tgaagatctt gcatctgtat ttgttggacc atctgcagta gcattttcta atgaagatgt
    26641 tatcgcacca gcgaaaatct tgaacgactt ttctaaaaac gctgaagcac ttgaaattaa
    26701 aggtggtgca atcgaaggcg ctgtcgcatc taaagaagag attcttgcac ttgcaactct
    26761 tccaaaccgc gaaggacttc tttctatgct cctttctgta cttcaagcgc cagtgcgcaa
    26821 cgttgctctt gcagtcaaag cggttgcaga aagcaaagaa gacgcggctt aatcttaagc
    26881 tacatagcgt agcctagcta cgaaaaaaac tattataaaa tttaaaactt atttggagga
    26941 aataacaatg gcattgaaca ttgaaaacat tattgctgaa attaaagaag cttcaatcct
    27001 tgaattgaac gaccttgtaa aagctatcga agaagaattt ggtgtaactg cagctgctcc
    27061 tgtagctgtt gctgcagctg atgctgctga tgctggtgct gctaaagatt cattcgacgt
    27121 tgaattgaca tctgcaggcg acaaaaaagt tggcgttatc aaagttgtac gtgaaatcac
    27181 tggtcttggt cttaaagaag ctaaagaact tgttgacggt gcaccagcac ttgttaaaga
    27241 aggcgttgca actgcagaag ctgaagaaat caaagctaaa ttggaagaag ctggagcttc
    27301 agttactctt aaataagagg catataccaa ttagaattcg gaatactata gtatcagcct
    27361 tttagaatcg tgaacacatt ttagaaactg ataaattaat ttagtttcct accaaaaacc
    27421 ctaccaaaaa ttctttggca ggatttttgt tttaataaac tttcgggggt agacactaga
    27481 ttgtctaccc tttttttgtg tttcggaggt aattatgcaa aaggaaggac agtcatcacg
    27541 tcaattcgtg aagagtcatc tcatgactat catgggagtt gatattgtaa aagcaactca
    27601 gttagttgat gaaatggaac aagtaggttt aatccgattt gatgaatttg gaaatgttgg
    27661 aattttagtc ttggagggac aataatgaag cgtattaccg ctaattaata tcagacatca
    27721 gagcgttatt ataagctccc caaactttta tttgagagtg aacggtataa gaatatgaaa
    27781 ctggaggtta aggtggttta ctcagtttta aaagatcggt tggagttgtc tttgagcaaa
    27841 ggttggattg atgaggatgg ggctatttat ttgatttatt ccaattcaaa tttgatggca
    27901 cttttaggct gttcaaagtc aaaattactc tccatgtgag tttgaagtga catttttaga
    27961 tgattaccat aaaaaacata actacccact attttacgaa tcctatcttc aaaacgttat
    28021 ggaattcctt gaaagtcaag acataaagaa tggggttgat gcctttgtag atgatcatca
    28081 aaatctcgtt tttgttttat atggacaagg ctatcgagcc gagggaaaag agggaatact
    28141 tacaacccaa gtaactgtaa aagcttatga tgaagacaag aaaccgatta acttcgcaaa
    28201 tttattagat tccttaatcg tgtcagaata tcaaatggaa ccgaatcttt gggaggtctc
    28261 ccatgattga tctctatcta agtaaaaata gccaaagaaa tcaacttctt ttagacttct
    28321 tccaaaacta tggcatcgag gtatcttgtc attcagtttc tgaaatgaca aaggacaaat
    28381 taattgagat gatgagctat tcttcagatt gttttgagtt tttatctccc aatttattac
    28441 gatttaagaa ccgtgacaat ctaagattaa cggatttcgt tgagataatt ttaaaaaatc
    28501 ctgaactaac catcagactt cctcttgtgg tttcaaataa gcgggtttat ccaagtctga
    28561 atttggaaga ggctagagct ctattgccaa gagatacgaa acaattgatt tacatggcac
    28621 aaacacatta tttatataac taaaggagaa gcaatatggc tgaacgattt tgggagaact
    28681 tgtccattat tttggctgaa agaaatatca gctggattga gttaaccaga aaaatgtttg
    28741 cgggagagtt tcactatcca agtgaattga atcgtttgta tcaaaagatt cgccactaga
    28801 agatggaaca atgaatgcct caaagtccat gggtagaaag gattgtgcag gtattagatt
    28861 tagattatga agatttattt cggaggtaac tatgaaaaga ataattccag tttatatatt
    28921 ccaacaagta aatgtcctat tggtatctct atacttattg aaatttcttt gtatcggtga
    28981 gttaactata ctacagattc tctatggttc gtcactcatt tcttttttat ggatgtatgg
    29041 ccaacgcaaa caagctcata aggtaaatat gaaatctagg atgaaatggc ttggtattgg
    29101 attcgttagc ctactgatta taagtctatg ttttagccta atccatgcgc aagaaagcac
    29161 gaatcaagca aacttaattg gacttcaaca tcaagttcct tggttttcat ttttattgtt
    29221 tttaatcaat gcgagtatgg ttgaagaatt tctgtataga gaaattttat ggaacttggt
    29281 tagaaaatta gatattcgag ttgctttgac aagtgtttta tttgccttag cacatcatcc
    29341 aggaaccatt atagcttggt gtttgtatgt atcgctgggg atgtttttag ggcttgtacg
    29401 ctacaaattg gacttatggg gcagtatggg gctacatttg gtgtggagcc tactagttta
    29461 tagtttgctg cttttttaaa ataggtaacc tgatttttag gtaacttcta aaactaactt
    29521 ccagttttgg gagagagatg gaagttactt tgaaaagtta cggaaacatt attttctatg
    29581 tgacaacatt gtatcattgc ttgcatttta ctgctggaga gagtataatg aaggtggata
    29641 aagcacttaa tcctaaaaat ttaaatagga ggagttagct atggcagaag aagtattaaa
    29701 tcttcaatta gtatctgttc aagttgacga aacagatgaa gttgatggaa tgcgatttag
    29761 tacattcagt acaaaccgtt gcggtaactg gagtgctttt agttgggaaa attgttaatt
    29821 catttaaatt gtaaacttta gggattctct gaagttatgg atgtcgttcc aatatgtgta
    29881 cgttggaatg ttagtgctta tatgggggga acagaatcct ctcttgattg aagacaagtt
    29941 agccattagg ctggtttgtc tctttgtcaa ctgtagtggg ttgatataat agtattagtg
    30001 agtgggataa aagtttcatt tagtttattc agtacaaatt taacgggtca agatttatac
    30061 aattggtaat caaattactg aagtccttca tgaacattat gacatttcta aagaggaggc
    30121 aaataaacgt gctatagaaa tgttagaaaa acttggaatt cataatgctg cagaacgcat
    30181 gaatgactat ccacaccaat ttagtggagg gcagcgtcaa agaatagtca tagcgattgc
    30241 aatggtatgt aatccagata ttctaattgc agatgaacca acaactgccc ttgatgtaac
    30301 aatccaagca caaatacttg atttacttga tgatttacgt aaagagcatg gaacttctat
    30361 tatcttaatt actcacgatt taggcgttat tgctcaaatt gcggatgaag ttgcagtgat
    30421 gtatgctggt gaagtcgttg aagttggaac tgtagctcag atctttgatc aacctaaaca
    30481 cccgtatact cgttctctat taagatctat tcctaatcct gaaaatatgg ataaaaagct
    30541 acatgttatc caggggagcg taccttcaat ttctgaaata tctgaaaaag gatgcagatt
    30601 cgcaaatcgt attccatggt tagaaaaaga acatcatgaa gaagaacctc aattgcatga
    30661 tttaggtgac ggacattttg taaggtgttc ttgctataaa catttctttt tcgaagataa
    30721 ggaagaagaa acattagcgg aaaaacatgt aggtaatgtt gttttagaag taaaaaatat
    30781 taaaaagtac tactatccta agaagcaact attcaagcca ctaggttctc cgttgaaagc
    30841 acttgatgac gtatctctag agttaagaaa aggaactact attggtatcg taggagagtc
    30901 tggaagcggt aagagtacga ttgcgaaatc attaatgaaa ctccatgata ttacagatgg
    30961 tgaaatcaat attgatttga atgggaaaac tcaaaatatt tatggaatta aacgtaagga
    31021 agatttggat ttccgtaaga aagttcaaat ggtattccaa gatccttatg catcattgaa
    31081 cccaactaag aaaatttata attcatttga tgaaccgatg attgtccata atattggaaa
    31141 caaagaggaa cgctttgaac gtatgaaaga agccttgaag atggtaaacg tgccagttga
    31201 gtacttggag cgttatcctc atgaattttc aggcggacaa cgtcaacgtt tatgtattgc
    31261 tcgtgccctt tgtatgaaac cagaaatttt aattttagat gaacctgttt cagcattaga
    31321 tctatctgta caagcgcaag ttttgaatta tcttgttgaa atccaaaata aagaagattt
    31381 gacttatgta tttatttctc atgacctagg tgttgtgaaa tacatgtgtg actatctata
    31441 tgttattcat aaaggacgta ttgtagaagc tggttctcga gaagatatct acaataaccc
    31501 aatgcatatt tacactaaaa aactattagc tgctattcca gaagttgatt atcacttcaa
    31561 agaggcattg gcaacaaaac gtaaagaaaa tgaagttgaa tttaaagcac agtaccatga
    31621 attttatgat gaagatggcc gtgcttatga tcttaagcag gtttcaccaa cacattttgt
    31681 agcgttaaaa ccagaatagg tggtaaatat gaaattaaat aaaaaaatat atttctttga
    31741 taaaggaatt tttaatcctt atcgaatgag taatgtaaaa ttaaaagtta atcaggcagt
    31801 aaaggataaa gaaattttct tcactgagga aaaaccatgg gaaattcgtt ttgataacag
    31861 ttatccaaat gttttctttg atgatttagc aggtgtttat cgttgctact attctacatt
    31921 tactgatgat gaggagtctg aaaaatactc tttagaggag cgtaaggaac gtcaatatct
    31981 acctcgtgcg aagcgtattg tttcactttg ttatgctgaa agtaaagatg gtgttaactg
    32041 ggtgaaacca aatctaggta ttacagaatt tcgaggatca actgaaaata atattatcgg
    32101 acatttttta catggtacat ctgtttttct agataaacat gacgcagatg aaaatcgtcg
    32161 ttataaaatg tttacaaaga ttgattacgg taacggtgtt catttcattg ctgtagcatt
    32221 ttcaaaagat ggtctacact ttgatgaata cattaaagta ccaaacttca atccacgtgc
    32281 agacactcat aaccatatca tatatgatga agcattaaat cgctatgtgc taattactcg
    32341 tacttggaga gattcattgc gcttgccgtg tgtatctacg agtgctgatt tcattaactg
    32401 gactccaatt caagaaattt tgaatgtctg tgattatgaa aatcaaattt attctatgcc
    32461 tatttttaaa cgtggcgatt atatactagg tttagcttca gttttccatg aaggagatca
    32521 actgaacaag aattacgata cagtggacct tcaattgact tatagttatc gtcatgttgg
    32581 ttggcattat ctaaacactg atactccact tattcctcgt ggtaaaggtc aatatggtga
    32641 tggagaattt gactgtggat gtatctattc ttctgcacca gttactatcg gtgaccgtac
    32701 ttatttctac tacatgggag gaaatggaca acatacaaac ttccgtgaaa caagcttgtc
    32761 tcgtgcttat attgagaaag atcactttgc atattgggat actaaacgtc cagaatatcc
    32821 aggtgttttg tataccaatg gatttatttt cctcaatgat caagtttacc ttgatgcaga
    32881 tattgcagct ggaggctttg taacaattga attgttcgag aataatcaca ctccaatgga
    32941 aattacagct tcccttgaaa aaatagaaga tggtcgctat caagtgttat tcagcgaacc
    33001 tttacctcga actcaaactc gactgaaaat tagctttaaa aatgctaaaa tctacgcaat
    33061 cgaaggaaat ttagatattt tcagaattga atcagacaat gctctattga gggggtaaga
    33121 ttatgaaata tgatttatat gataattgta ttgaacttct aaaagaacgc gaagttacaa
    33181 ttgaagatat ggcagcgtta gtaatatttt cacaacaaaa atattaccct gaattaactc
    33241 ttgacgacgc ttcatatgca attcaacgtg tactaaaaaa acgtgaagtt cagaatgtaa
    33301 ttatgacagg aattgagtta gataagttag ctgaagcaca aaaactatct ccagaatttc
    33361 aaaagattat ggagaaagat aatccattgt atgggattga tgaagtaatc gtcttatcga
    33421 tattgaattt atatggttct attgccttta caaattatgg ctatttagat aaattaaaac
    33481 cactgatttt agaaagattg aatgagaatc acgaaggtgt ttgtaatgta tttctagatg
    33541 atattgttgg tgcaatagcc gcagcagcat gtagtaaaat tgcacacaat catgctagtg
    33601 atgaaatata actattgaat ttagtatcgt aaataataaa gcgtttggtt tctagattat
    33661 tgtcattcaa attggataat gataaatcta gaaaccaaat atattttccg cataaaatga
    33721 gggattatat atctcacttt tttacaattg tatagtggat taaaactaga atagtgcatc
    33781 tctacttcta aaacattgtt agaaa
//
LOCUS       DAVHSL010000021        33691 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000021 DAVHSL010000000
VERSION     DAVHSL010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.021"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            354..2369
                     /locus_tag="VVR39_000999"
     CDS             354..2369
                     /locus_tag="VVR39_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6030506.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2371..3003
                     /locus_tag="VVR39_001000"
     CDS             2371..3003
                     /locus_tag="VVR39_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030507.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            3144..3422
                     /locus_tag="VVR39_001001"
     CDS             3144..3422
                     /locus_tag="VVR39_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEU6030508.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(3931..4344)
                     /gene="ndk"
                     /locus_tag="VVR39_001002"
     CDS             complement(3931..4344)
                     /gene="ndk"
                     /locus_tag="VVR39_001002"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU6030509.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(4455..8132)
                     /gene="rpoC"
                     /locus_tag="VVR39_001003"
     CDS             complement(4455..8132)
                     /gene="rpoC"
                     /locus_tag="VVR39_001003"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU6030510.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8165..11776)
                     /gene="rpoB"
                     /locus_tag="VVR39_001004"
     CDS             complement(8165..11776)
                     /gene="rpoB"
                     /locus_tag="VVR39_001004"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6030511.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12192..12262
                     /locus_tag="VVR39_001005"
     tRNA            12192..12262
                     /locus_tag="VVR39_001005"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12224..12226,aa:Cys,seq:gca)
     gene            complement(12460..13791)
                     /locus_tag="VVR39_001006"
     CDS             complement(12460..13791)
                     /locus_tag="VVR39_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU6030512.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14020..14844)
                     /gene="endA"
                     /locus_tag="VVR39_001007"
     CDS             complement(14020..14844)
                     /gene="endA"
                     /locus_tag="VVR39_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU6030513.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(14883..15071)
                     /locus_tag="VVR39_001008"
     CDS             complement(14883..15071)
                     /locus_tag="VVR39_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6030514.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15064..16347)
                     /gene="murA"
                     /locus_tag="VVR39_001009"
     CDS             complement(15064..16347)
                     /gene="murA"
                     /locus_tag="VVR39_001009"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6030515.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16371..16601)
                     /locus_tag="VVR39_001010"
     CDS             complement(16371..16601)
                     /locus_tag="VVR39_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU6030516.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(16659..17696)
                     /locus_tag="VVR39_001011"
     CDS             complement(16659..17696)
                     /locus_tag="VVR39_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU6030517.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFLRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(17680..18168)
                     /gene="coaD"
                     /locus_tag="VVR39_001012"
     CDS             complement(17680..18168)
                     /gene="coaD"
                     /locus_tag="VVR39_001012"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU6030518.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18158..18697)
                     /gene="rsmD"
                     /locus_tag="VVR39_001013"
     CDS             complement(18158..18697)
                     /gene="rsmD"
                     /locus_tag="VVR39_001013"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU6030519.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLIFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(18762..19754)
                     /locus_tag="VVR39_001014"
     CDS             complement(18762..19754)
                     /locus_tag="VVR39_001014"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU6030520.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(19866..20549)
                     /locus_tag="VVR39_001015"
     CDS             complement(19866..20549)
                     /locus_tag="VVR39_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU6030521.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20605..21345)
                     /locus_tag="VVR39_001016"
     CDS             complement(20605..21345)
                     /locus_tag="VVR39_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU6030522.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            21379..21657
                     /locus_tag="VVR39_001017"
     CDS             21379..21657
                     /locus_tag="VVR39_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU6030523.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            21735..22661
                     /gene="yidC"
                     /locus_tag="VVR39_001018"
     CDS             21735..22661
                     /gene="yidC"
                     /locus_tag="VVR39_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6030524.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(22736..23530)
                     /gene="pflA"
                     /locus_tag="VVR39_001019"
     CDS             complement(22736..23530)
                     /gene="pflA"
                     /locus_tag="VVR39_001019"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU6030525.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(23656..24906)
                     /locus_tag="VVR39_001020"
     CDS             complement(23656..24906)
                     /locus_tag="VVR39_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU6030526.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTSD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(24973..25800)
                     /gene="purR"
                     /locus_tag="VVR39_001021"
     CDS             complement(24973..25800)
                     /gene="purR"
                     /locus_tag="VVR39_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU6030527.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26067..27008)
                     /locus_tag="VVR39_001022"
     CDS             complement(26067..27008)
                     /locus_tag="VVR39_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU6030528.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(26998..28254)
                     /locus_tag="VVR39_001023"
     CDS             complement(26998..28254)
                     /locus_tag="VVR39_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU6030529.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28256..28918)
                     /locus_tag="VVR39_001024"
     CDS             complement(28256..28918)
                     /locus_tag="VVR39_001024"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU6030530.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(28881..29537)
                     /locus_tag="VVR39_001025"
     CDS             complement(28881..29537)
                     /locus_tag="VVR39_001025"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6030531.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(29548..30426)
                     /gene="rsgA"
                     /locus_tag="VVR39_001026"
     CDS             complement(29548..30426)
                     /gene="rsgA"
                     /locus_tag="VVR39_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU6030532.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30428..31300)
                     /gene="rsmA"
                     /locus_tag="VVR39_001027"
     CDS             complement(30428..31300)
                     /gene="rsmA"
                     /locus_tag="VVR39_001027"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU6030533.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31551..31844)
                     /locus_tag="VVR39_001028"
     CDS             complement(31551..31844)
                     /locus_tag="VVR39_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030534.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQILVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(31837..32478)
                     /locus_tag="VVR39_001029"
     CDS             complement(31837..32478)
                     /locus_tag="VVR39_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030535.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLEKQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32480..>33691)
                     /locus_tag="VVR39_001030"
     CDS             complement(32480..>33691)
                     /locus_tag="VVR39_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6030536.1"
                     /translation="KGKLPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERA
                     SNKWSQSSDRYRLSFGWSSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFS
                     DGAEVDLDGNRLSDYTPSGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPE
                     SLREQSTYYQRLFTDYLQNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTT
                     RQYLKDPIIVVLTPQATGTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSY
                     LVKSQLFFAKVLNDKRVEFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLA
                     GMTIYELHGKYLLAQGGVLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKE
                     EAGSMAVLKGK"
BASE COUNT         9537 a         7666 c         6640 g         9848 t
ORIGIN      
        1 ttaaaataag gataatgaaa aagaaaaggg tttcacgaat gaagaaaaat cgtggaattc
       61 aaaaattagc tatattagta ttactaggtg tttttatgtt tagtaataca attccttacc
      121 aacagtttat tcagaagaat agacaattgg agattcgagt gcaatcgcaa aagaagtcca
      181 atggtcttga tgttgggaag gctgattgat ttcgtattac tttaaaattc aactatttag
      241 agaaaggtat tctgatgaga gcttgtaaca ataccagata gatattagta agcttgttag
      301 tttatagagg gcaggggtat ttctgccctc tgttttagaa taaggaatgc actatgaaaa
      361 aattatttat actcatatcc aacctgcttg ctagtttgtt ctttgtttgg gtatttacca
      421 tttggactga tacatatgtc tcctattatt accccaacgt tgttgtacat gattcttccc
      481 ctgaaacaac ttttcagcat gttgctacac gcttggaaaa actagcagaa gaaacagata
      541 gctttattgc gattcaacac caagattcta actcagaagg tactacagtt ttttcttata
      601 cgacctttgg ggacggaaag ttgcctgatg ggcttcagga aaaaaatcta gaagatgctc
      661 aaagtagtag tgttgaaaca aactattttg tattcgatgg acacctagat attcacttgc
      721 taagggaaga gctaagtcaa cttggcttga ctaacatgca cctgacaatt ccatctaaac
      781 tatctacgtt aatggctatc tttagtaacg gatttcagtt aatcagtcta ttgattttca
      841 tcttaacctt tgtagcactg actttaatta gtcaaattag ccaattacgg tcatcgggca
      901 ttcgcctcat ttcaggagag aaacggtggt ccattttcct tagaccagtt ggtgaggatt
      961 tgaaagcgat agctgttggt ttcagtttag ctggcgtgct cgccattctt atgcaaaaaa
     1021 ttctgtcgct tccaacgcaa tccctaatga ccataggagc aggcttgctc agttataatc
     1081 tcatcttgtt gtcgatctcc ctgtttttcg ctcaactctt cgcagttggg ataaaaaaga
     1141 tacacctgat gcagattata aaagggcaag tgcctgtcag aggaatcatt agtttgattt
     1201 taatcggtca actgttagcg attattattg taacgctggg aatagggagt agcttaaagt
     1261 attcccaagc ctggcaacag catcggattg gacaagaggc ttggagtcag gaaaggcaac
     1321 tgattaccct atcaatcagc cgtgaaggaa cgagtcctgg ttttgatgaa caagctcaaa
     1381 ggaaactcag aacttggtat caattgatgg atctggctgt ttcagaacaa aaggctttct
     1441 tatctagaca ccagttaatt gaccgtactt tgcaaaatgg catggcttcc tccaaaaact
     1501 tgataacctc tacagaatgg cacgattaca acccaaatgg caatgtcctt atcgtcacac
     1561 cgcaatactt ggagcgtcaa aacattcctg tagatacaac tattgagcaa aagatgaatc
     1621 accttgatgt aggggagttt gtcttattgc tgcctgaaca cctccgttca gaggaagaac
     1681 attataaatc tgtttttgaa gacgacttaa ccagtcgcat gtctagtcaa gatgaacgac
     1741 agcaaatgac tgctacggta ggttatttag aatcaggtca ggatcgtttt gtgtataata
     1801 cgacccctat ttcttaccag cagtttttga aagatccaat catcattgtt ataacacccc
     1861 aatcaactgg tccacagtcc attttgtttt ggatagacgc agtacagaac tacgttctct
     1921 ttaatcaatt gtctgatgcc caggagctta tccagagaca aggcattgaa aattgggtct
     1981 cagaaatgca aacaggttac cacaactaca tcacattatt ggataatatc cagagggaac
     2041 gttgggtaat gctagcagga gctgtgcttg ggattgcaac ttcaatcttg ttgtttaaca
     2101 ctatgaatag gctctacttt gaagaattta gacgtgccat ttttatcaaa cgcattgcag
     2161 gtctcaggtt cttagaaatc catcgcactt atctctttgc tcaactgggt gtgtttttac
     2221 tgggatttgt tgcgagtgta tttcttcagg tagagatagg agttgctttc ttagtcttgt
     2281 tactctttac tggtctatct cttttacagt tacatgtcca aatgcagaaa gaaaacaaga
     2341 tgtccatgct tgttttgaag ggaggttaat atgattgaac ttaaacaggt gagtaaatct
     2401 tttggagaac gagagttatt ttcgaatctt tcaatgacat ttgaggctgg aaaagtctat
     2461 gccttaattg gttcaagtgg tagcggaaaa acaaccttga tgaacatgat tgggaaatta
     2521 gaaccttatg atgggacgat tttttaccga ggtaaagact tggccaatta taaatcgagt
     2581 gattttttcc gtcacgaatt gggctacctc ttccagaact ttggcttaat tgaaaaccaa
     2641 agtattgaag aaaaccttaa gctaggtctc attggtcaaa agttgagtcg gtcggaacag
     2701 cggttgaggc agaagcaggc tttagaacag gtcggcctgg cttatcttga cctagataag
     2761 cgcatctttg agttatcggg cggagaatcg caacgggttg ccttggcaaa aattatctta
     2821 aagaatccac cctttattct ggcagatgag ccaacagctt caatagaccc agcaacctct
     2881 cagttgatta tggagatttt gctatctctt cgagatgata ataggctaat cattatcgca
     2941 acacataatc cggcaatttg ggagatggct gatgaagtgt tcacgatgga tcatctgaaa
     3001 taaaaatcct tgtttttaat tgcacgatga gttactgaaa tattatcatg aatcaagaat
     3061 tggagttaat ttagaattgt actttattaa tattgaggta actttttctt gataaaggaa
     3121 gaaataatgg agaggaagtt agaatgaaaa aattcgacaa ttatattatt gagaagcctt
     3181 gcgattctaa ttcagataaa ctgcaaaaaa tcttaataat tgaaaatttg gtagatgata
     3241 ttttgcaatt tcctctcaga atcaataata gtgtaggaga gattttcctc ctacaaccgt
     3301 ttcaaaagaa aactatcttt attccatgtt attttgagga agatattgtg aaagtcaaag
     3361 atgatgataa agttgagtgg aatttgttag aatttcaaaa atttagagca tttttggctt
     3421 agtaatctgt gttgaaggct caaaacctat ggtaaaaaag tcgctttgaa aacgtattgc
     3481 ctccaaagat ttagttaaat aatgatttaa cacaaaaaga aattattgaa gttctggaaa
     3541 gatgttgttt cagtattgag aaaagatggg aaaaacttgc gattttcaca gagaaaggaa
     3601 gaaaaagtat agaaatatag tcaattgaaa caagaacagg acaaaagaac cttttgtgcc
     3661 atatttttct cctttcgctt tacaattggc ttgaacacct ttattgtatc gcgtttggag
     3721 tttttttggt ataaccttcg acgcgcaccc gcatagtggg tgtttttttg tctcgcacct
     3781 aacggagcga gacaaactaa tagtcactta atcaaaaaac gcaccatatc aaaaactaaa
     3841 aagtttgata tcatgcgtca tgtcttaaac taattgacta tactttctat tcaaatgagc
     3901 ttttaaccaa ttgattgagc caatccactc ttaaaaccaa agagcaattt ctcgcttagc
     3961 tgactcttct gaatctgaac catgtacaac attttggata atctcatttt ctccagcagc
     4021 ttttgcaaaa tcacctcgaa tagtgcctgg taaagcttct tctggacgag ttgcacccat
     4081 catggtccgc caagtttcga ttactttggg accagaaatg acacccacaa gaactggacc
     4141 tgaagtcatg aattcacgaa tcggtgggta aaaactctga ccaaccaagt cctgatagtg
     4201 ctggtcaatc aactcttctg aaacctgtga acgaaactcc aatttttcga ttgtaaatcc
     4261 acgttgttcg atgcgcttta acacttcacc cactagccct ctttttacac catctggttt
     4321 gatgataaag aatgtttgtt ccatacccgt ctcctttgtc agcttctttc ttttatttta
     4381 ccacatttcg tggaaaaatg gagaaagttt tcagaagaga gaatgagaga accctcgggt
     4441 tctctcattc tctcttattc tactgtttct tccacagttt caacggcagt atccacaact
     4501 acttctgttg tttcttcatt tccttcttcc tctactggag gattaaggta ttcttcttcg
     4561 ttgacagcat atggttcaag gttacggtaa cgggccatac cagtaccagc tgggatgatc
     4621 ttaccgatga taacattttc tttaagtcca aggagatggt ctttcttacc acggatagct
     4681 gcgtcagtaa ggacacgagt tgtttcctgg aaggaagccg ctgacaagaa actgtttgtt
     4741 tcaagtgagg ctttggtaat tcccataagg actgggcgac ctgtcgctgg aactccacct
     4801 gcgataagga catctttgtt ggcatctgta aagtcattga tatccatgag ggtacccatg
     4861 agaagatctg tatcacctgg atccatgaca cggactttac ggatcatttg acgaaccatt
     4921 acctcgatgt gtttgtcacc gatttctacc ccttggctac ggtaaacttt ttgtacttca
     4981 ccgagaaggt acgtttcaac tgacaagaca tcacgaactg caaggagacg ttttggttgg
     5041 atagaacctt ctgtcagagc agcaccacgc gctacttggc ccccaacttc gacacgcata
     5101 cgagctgtaa atggaacgac atattcacct tcgccagttt cacccttaac aaagactttc
     5161 ttggtacgag ttgatgcatc ttcttcgata gcagtaactt gtcctttaac ctctgtaata
     5221 accgcttccc ctttaggatt gcgggcttca aagatttctt ggacacgagg aagaccctga
     5281 gtgatatcgg tatttgaggc aaccccacct gtgtggaagg tacgcattgt aagctgtgta
     5341 ccaggttccc cgatagattg ggcagcgatt gtaccaactg cttcaccaac ttcaaccgca
     5401 tcaccagtcg ccaagttgat accgtaacag tgacggcaga caccgtgacg agtgttacat
     5461 gtaaatacag aacggatagt cacttcttcc acaccagcat tgacaatttc acgcgccttg
     5521 tcttctgtaa tcaattcatt tggaccaata atcactgcac cagtttctgg atgtttaaca
     5581 gttttcttag tgtaacgacc gttgagacgc tcttcgagag actctatcat ctcttttcct
     5641 tctgcgatag aacggatcaa gagaccacgg tcagttccac agtcgtcctc acggatgata
     5701 acgtcttggg caacgtcgac caaacgacga gtcaagtaac ctgagtcggc tgtcttaagg
     5761 gccgtatcgg tcataccttt acgagcaccg tgagttgaga agaacatttc caataccgac
     5821 aaaccttcgc ggaagtttga aaggattggc aattccatga tacgtccatt cggagcagcc
     5881 atcagaccac gcataccggc aagctgtgag aagtttgaga tgttaccacg ggctccagag
     5941 tccatcatca taacgattgg gttcttagga tcttgattag caatcaagcg tttctcaagt
     6001 ttttcacggg cagcacgcca ttcagctgta acagcattgt aacgctcgtc gtctgtgatc
     6061 ataccacgac ggaattgttt ggtgatttgt tcgacacgtt tgtgtgattc ttcaatgatt
     6121 tcagccttgt catcaacgac tgggatatcg gcaataccca ctgtcaatcc tgcaagagtt
     6181 gagtggtggt aaccgaggtt cttcatgcgg tcaagtaggg cagaagtttc tgtcgtacgg
     6241 aaacgtttga agatttcagc gatgatattt ccgaggtttt tcttcttgaa tggagggttg
     6301 agctcaagat tgctgatagc ttccttgata tctccaccaa gtggcaagaa gtatttagct
     6361 ggaacacctt ctgtcaagtt ggcattgttt ggttcttgca agtatggtag cccctctggc
     6421 atgatatcgt tgaagagaat tttaccaact gttgtaagca agaccttatg tctttgctct
     6481 tctgtccaag gcttgttgag gctgtctgtt gcgataccaa cacgtgagtg gaggtgaaca
     6541 taaccattgc ggtaagccat aaccgcttcg tcacggtctt tgaagaccat tccttcacct
     6601 tcgcgaccag cttcttccat ggtcaagtag tagttaccca aaaccatgtc ctgagatgga
     6661 gtaactaccg gtttcccatc tttcgggttc aagatgtgct cagcagctag catgaggata
     6721 cgagcttctg cttgtgcttc ttctgaaagt ggtacgtgga tggccatttg gtccccgtca
     6781 aagtcagcat tgtaggcttc acagacaagt gggtgcaagc gaagagcctt accatcaatc
     6841 aagactggct cgaaggcttg gatacccaaa cggtgaaggg tcggtgcgcg gttcaaaagc
     6901 actgggtgtt ctttaatcac ttcttcaagg atatcccaga tacgctcatc tccgcgttcc
     6961 accaagcgtt tagctgcttt gacgttttgc acgatatcac gggcaacgat ttcacgcatg
     7021 acaaatggtt taaagagttc aatcgccatt tcacgtggca caccacattg gtacatctta
     7081 agagttggac caacggcgat aacggaacgt cctgagaagt caacacgttt accgagcaag
     7141 ttttgacgga agcgtccttg tttaccttta agcatgtggc tcaatgattt caatggacgg
     7201 ctacctggtc ctgtgattgg acgaccacga cgaccattgt caatcaaagc gtcaactgct
     7261 tcttgaagca tacgcttctc attttgaacg atgatacctg gtgcatttaa ctcaagcaaa
     7321 cgagccaaac ggttgttacg gttgataaca cggcggtaaa ggtcattcaa gtcagatgag
     7381 gcaaaacggc caccatccaa ctgcaacatt ggacgaagat ctggtgggat aaccggaagg
     7441 atgttaagaa tcatccattc aggtttgttt ccagacttgt aaaaggcatc caaaacatcc
     7501 aaacgacgga tggctttgac acgtttttgt ccagtagctg ttttcaattc ttctttgagt
     7561 tcagcaattt ctttttcaag atctacttgc ttcaaaaggt cttggatggc ttccgcaccc
     7621 atcttggcaa caaatgaacc ataaccatat tcacgcaagc gctctcggta ttcgcgctct
     7681 gtcatgatag acttgtgctc aagtggtgta tccttaggat caattaccac ataagccgca
     7741 aagtagataa cttcctcgag ggcacgaggg ctcatatcaa gggtcaagcc catacggctt
     7801 ggaatcccct tgaagtacca gatgtgagat acaggagctt tcaattcgat atgtcccata
     7861 cgctcacgac gaactttcgt acgcgttact tcaaccccac agcggtcaca aacaattcct
     7921 ctgtaacgaa tgcgtttgta cttaccacaa gcacattccc agtcttttgt aggaccaaag
     7981 atcacttcat caaagagtcc ttcacgttct ggtttcaagg tacggtaatt gattgtttca
     8041 ggttttttga cttctccata agaccatgaa cggactttac ttggagaagc tagggtgatt
     8101 tgcatacttt taaaacgatt tacatcaacc actatttctt ccctttctat tctaagtgaa
     8161 ctgcttattc ctgttcagca gcttcttctg ttgcttccgc ttttgttgct ttctcagctt
     8221 cttcagcttc aaaggctgct ttagcctctt gggctgcttt ttcgcgggct ttttcaaggt
     8281 catctacgtg gatgacatct tcgtccattc cttcatccaa gtcgcgaagt tccacttctt
     8341 ggtcatcttc gtctaggaca cgcatgtcaa gaccaagaga ttgcaattct ttgacaagaa
     8401 ctcggaagga ttctggaaca cctggttttg gaattggttt gccttttgta atagcttcat
     8461 aggctttcaa acgtccgttg atatcgtccg acttgtaagt caagatttct tgaaggacat
     8521 ttgacgcacc gtaggcttca agagcccaaa cctccatctc accgaaacgt tgtccaccaa
     8581 actgagcttt acctccgagt ggttgttggg taacagttga gtaaggtccg actgaacgcg
     8641 cgtgcaattt atcgtcaacc atgtggtgga gtttgatcat gtacatgact ccaacagaaa
     8701 cacggttatc aaatggttca cctgtacgtc catcgtaaag gattgtcttg gcatcgctat
     8761 ccatacctgc ttctttaaca gttgaccaaa gatcttcaga acttgctcca tcaaagactg
     8821 gtgtcgcaat gtgaatacca agagtacgag ctgccatacc aaggtgaagc tccataacct
     8881 gaccgatatt catacgtgat ggcaccccaa gtgggttcaa catgatgtcg actggagttc
     8941 cgtctggaag gtaaggcatg tcttctacag gaacgatacg agagacaacc cctttgtttc
     9001 cgtgacgtcc ggccatttta tctccgacct taatcttacg tttttgagcg atgtaaacac
     9061 gaaccaacat gttaacacct gattgcaact catctccatt tacacgtgta aagatcttaa
     9121 catcacgaac gacaccatcg gcaccgtgtg gtacacgaag agaagtatca cgcacttcac
     9181 gagacttgtc tccaaagata gcgtgcaaga gacgttcttc agctgaaaga tctttctcac
     9241 ccttaggtgt tactttacct acaagaatat caccttcttt aacctcagca ccaatacgga
     9301 taatccccat ttcgtcaagg tctttgaggg catcttcacc aacgtttgga atttcgcgag
     9361 tgatttcttc aggcccaagc tttgtatcgc gcgtttctga ttcgtattct tcaaggtgaa
     9421 cagatgtgta gacatcgtcc ttcaccaagc gttcgctcat gataacggca tcctcgaagt
     9481 tgtaaccttc ccaagtcatg taggcaacga ttgggttttg tccaagcgcc atttctccat
     9541 tttccataga aggtccgtca gcgatgaaat cgcctttttc aacgacatca ccaactttta
     9601 cgagagtgcg ttggttgtaa gcagtacctg agtttgaacg acggaatttt tggatgtggt
     9661 aaacatccaa tgaaccatct tcacgacgaa cttctacctt gtcagcatct gcgtaagtaa
     9721 ctttaccatc atactgagca atcacagccg caccagaatc gtgggctgct tggtattcca
     9781 taccagtacc aacgtaaggt gcctgaggat taatcaatgg cacagcctga cgttgcatat
     9841 tggctcccat gagggcacgg ttggagtcat cgttttccaa gaaaggaata catgctgtcg
     9901 caacggcaac tacctgtttt ggtgaaacgt ccatgtagtc aacaatatta gctggatact
     9961 cttggttgac cccttggtga cgtcccatga caatcttctc agcaaaggtt ccatcttcat
    10021 tcagacgaga gttagcctga gctacagtat attcatcttc ttcatcagct gtcaaccaaa
    10081 caatttcgtt cgtgacaaca cctgtttcac ggtcaacctt acggtatggt gtttgaacaa
    10141 aaccatattt gttcaagtgt ccgtaagatg acaagttatt gatcaaaccg atgttaggtc
    10201 cttcaggtgt ctcgattgga cacatacgac catagtgagt gtagtgcacg tcacgtactt
    10261 catatccagc acggtcacga gtcaaaccac caggtcctaa ggctgacaaa cggcgtttgt
    10321 gagacaactc agaaagcggg ttgtgttggt ccatgaactg tgacaactgt gatgaaccaa
    10381 agaattcttt aactgcagct gttacaggac ggatattgat aatttgttgt ggtgtcaaga
    10441 cttcattgtc ctgaacagac atacgttcac ggacattacg ttccatacga gaaagtccca
    10501 aacgtacttg gttggcaagc aattcaccaa ccgcacggat acgacgattt ccaaggtggt
    10561 cgatatcatc tacacggcca agtccttcag ccaagttgag gaagtagctc atctcagcaa
    10621 ggatatctgc aggagtcacc gtacgaacct tgtcatctgg gttagcatta ccaatgatcg
    10681 ttacgacgcg atctggatca gttggagcaa caaccttgaa tttttgaaga acaacaggct
    10741 cagtcacaac ggctgcatcg tttgggatgt agacaatctt gttcaagtcg ccatccaaat
    10801 ggctttcaat gctttcaatc acgctacgag tcataatcgt accagcttct accaagattt
    10861 ctccagtttc agggtctacc aatggctctg caatggtttg gttgagcaaa cgtgttttaa
    10921 cattgagttt tttattgatt ttgtaacgac caactgctgc caagtcatag cgacgtgggt
    10981 caaagaagcg agccacaagc aagctacgtg agctttcagc tgtcttaggc tcacctggac
    11041 gaaggcgttc gtaaatttct ttcaaggctt cgtctgtacg agagtccatt ggattcttgt
    11101 ggatatcttt ttcaacagtg ttgcgaacca attcgctgtc accaaagata tcaaagattt
    11161 catcatcacc tgagaaacca agagcacgaa ccaaggttgt aaatggaatc ttacgagtac
    11221 ggtcgatacg agtgtaggtg atatcttttg agtcgctttc aagttccaac caagctccac
    11281 ggttagggat aacagttgaa ccatagccca ccttaccatt tttgtctact ttgtcgttaa
    11341 agtaaacacc tggtgagcgg accaactgag aaacgataat acgttcacca ccattgatga
    11401 tgaaagtacc catttctgtc atgattggga aatcaccaaa gaaaacttct tgggtcttga
    11461 tttcgcctgt ttctttattg atcaaacgga aggttacaaa aattggtgct gagtagctag
    11521 catcgtggat acgagcttct tctagcgtgt attttggttc cttgatttca tatccaacaa
    11581 attccaactc cattgtgtct gtgaagtttg aaattggcaa tacatcttca aacacttcct
    11641 taagaccgtg gtctaggaaa gctttgaatg agtcagtttg aatttcaatc aaatttggta
    11701 agtcaagaac ttctttgatt cttgaaaaac tacgacgggt acgatgtttc ccgtattgaa
    11761 cgtcatgtcc tgccaagatg attctccttt gtaaataagt tccaagcctt gtcaatcagg
    11821 cttttctaat cgccatatgg ttgtaaaccc cttatcaccg tgtcctcttg acgaattttc
    11881 agaatcttta agcctctgtt acaaatgctc aaaatcttga aaaaaagcac aaaaagagca
    11941 gctaaatctg actttttcag aagatttaac tgctgtgagc cttgtctgga caatatttca
    12001 gacaaaacct acgacaaatg attacccata ttatacccta tttagctaga tttttcaagg
    12061 ggtttcagta ggtttttggt aaattttttc ccatagaaaa cttggcatca cattcgaatc
    12121 acgctatggt acaaaaaact gaaaaaacta ttgactgaaa atcattttca aggtataata
    12181 ataaacgtta aggcggtata gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc
    12241 ggttcaaatc cgtctaccgc cttctataac ttgatttatc aggtttcaaa tgaacagaaa
    12301 gcccaatttg aagggctttt tttattttcc ctcgaataaa tacgtataac tttaaaaact
    12361 tttggagcga gtttgtggca gagttctttc catggcataa ttcccttttg aaatcaattg
    12421 aaaaaagctt cgtcacgcct ggtgacaaaa gcctctagtt tattctgttt cttcttctat
    12481 ttcgacttct gtgatttgga cttttacctt ggtaacacgt ccattcttca ctttatcatt
    12541 ggttaagata aactgtttgt tttggctaac caattcatag ctgagtttct cagtcgttgg
    12601 aatagttccc actcctgtca aataataacc agcgatggta tcaacgtcat cactttccag
    12661 ttcaacatca aagtaattat tgaaatcatt gagggtcata gttccttgaa caatgtaggt
    12721 atcctcgcca atctgatgaa catctattgc tgctttgtcc gtttcatcat caatttcacc
    12781 aacaatttcc tctaagaggt cttccaaagt caccaaacca gccataccac cgtattcatc
    12841 cagcaagatt gccatttgtc tttgggtatt tcgcagttct tttagcaagt catccacaaa
    12901 aatagtttca ggtacaaaaa gtggatcttg caaaattctc ttccaaacaa tattgtcaaa
    12961 accgtccaca aagcctgcct taaggagact cttggtgtga atgattccaa ttacattgtc
    13021 cttatcccca tcataaaccg ggatacgaga ataattttgt tttaaaatac tttggataat
    13081 ggcttgacta tcatcctgaa tatccaccat aaaggcatcc gttcgaggaa ccataacctc
    13141 tcgtgccatc agttcatcga gcgaaaagac accttgtagc atctcaatct catcagcatc
    13201 caatgtttct tcactatttg tcagcatata ggcaatttca tcacgggtca tcttttcatc
    13261 cgcatcatcg aatgacatag gagtcaaatg gctcaagaaa ttggtcgaag cagctaaaag
    13321 ccaaacaaaa ggactgacta gttttccgat cccaatgata accggcgctg tacgaattgc
    13381 caaggcatcc tttagattaa gagcgattct cttaggatat aattccccaa aaacgatgga
    13441 aatataggtc aaaaatgcca aggatagaaa agttgccacg gcttgtgctg tttcgccatt
    13501 cccaagccaa gaggcaatca cacgtcctag agtattagtt aaactcgccc ctgataagat
    13561 tgtaatcagg gtgattccta cctgaatggt tgataaaaag tggttaggat tttctagtac
    13621 cttcagcagg cggatgtagc gtctgtctcc ttcttccgcc ttttgttcaa ctcgggcacg
    13681 attaagagaa accatggcca tttctgtggc tgagaaaaag gcatttaata ccgtcaagat
    13741 aaacaataaa acaaattgta gcaacaaatt ctgactactt gggtcttcca tagttcttct
    13801 cctaaaatag tatcttatcc tttattatat cacaaaattt aatccaatac atattatttt
    13861 ttcttaccgt aacttctcaa agtaacttcc atctctctcc caaaactgga agttagtttt
    13921 agaagttgct attttttctt agtacctgtt ctagccctgc ttaaactagt aaaaagaact
    13981 cctacatcca taagtgacat aggagtttag gcttatcttt tactgagtta cagttacttc
    14041 tccagttcgg taatccagtt gaagtccctt ttgaacattg ggaactagaa cattgaattc
    14101 caattctcca tccgaagact tggcttcaat ctgtgaagct gagggaacta aatcctcgtt
    14161 tgaagcgtag taaagggtta cacggtaacg gacacgcttg ttttggtcca aggctttacg
    14221 caccttgctt tcatagtagt tttgaccagt cgaatactcg gcttgtgcct gatttgccca
    14281 ggctgtctga acagcaatgt ttttaggatt gcttgttgag gcatcaaaac catccaaacc
    14341 accgattaag gcatagccta acaaatgacc tctatcgact gcatgggtat aagagccctt
    14401 tagattcttg acctgatgcc aacctggagg agtccaagaa gttgaaccat tcccagtttc
    14461 tttacgattc ttgtactgac gagtggcctt agacaagagg gcattagcta cggttggaac
    14521 agtttccttg cccactgtct ttgttttatt gtcagcgtag ggcttacttg aaaccttggc
    14581 atctagattt gttttattac cattgacgat aaaagcacct gagccattcc actccagact
    14641 cccctttatt tgactcttga ctgcgtctgt taagacactc tctgccaatg cttgactagg
    14701 agcttcagac gcttgttttt tctgactaag attggttttg ggactattag gtgccgacgg
    14761 catctgcttg atataatagc tccctgtaga caaaagcaat aacactagca gtccgattag
    14821 tgtctgtctt gtttttttgt tcatatttct ccttatcttt agaaaaaggc tggttctcca
    14881 gcctaatttc ctgtaaattt atgaatcaat tcctgccatt ttgctggaga caggatagcc
    14941 catggatctt gacccttgcc caagattcca taacctacca ttagaccgat tcctagagcc
    15001 agagtaccta aaatcagtac tatgatgact aaaagtaaac gattgattac gtagcttgat
    15061 ttcttattca tcttcatcgc ttgcctcaat ccgctgaatc ttagcaccta gctgcgccaa
    15121 cttctcatgg aaaccgtagt aacctctatc caagtgaacc aatttaccga ccacagtttc
    15181 tccctgtgct accaaacctg tcaaaatcaa ggctgcactg gcacgaaggt cagttgaaag
    15241 aacttctgct ccctgcaaag gctgtccacc aacaatacga gctgtatcac ggataatctc
    15301 agaatgcaag cccatgcggc gcatctcttc taggtgttgg aaacgatttt cgaaaactgt
    15361 ctccaccatg gttgattcgc cttttgcaac tgtcatcaag gctgtaaatt gagcctgcat
    15421 atctgttgga aatcctgggt ggggcaaggt tttcacatga acagctttta gattttccag
    15481 ttgagaacga acacgaattc cttcgtcttc ttcaattact tcaacaccca tttcaagtaa
    15541 cttggcaatc aagggacggt tgtgctccca gacagcgtct cgaatcaaga catcaccacc
    15601 agtcatggca gcagctacca taaaggttcc tgcttcgata cggtcctgga ctacattgtg
    15661 agtcgtacca tgaagtttct caacaccagt aatggttata gtctctgtac cagcaccttt
    15721 gaccttggct cccatttcat taaggagaat ggctaagtca acaatctcag gctcacgcgc
    15781 agcattctca atcactgtca ccccatcagc cagagtcgct gccatcatca agttctgcgt
    15841 tgcaccaaca cttggaaagt ccatatagat atgagcacca tgcaagcgtt ctgccttggc
    15901 ttcgatgtaa ccagctgtct gactaatctt aacccccata gcttccagac ctttcaaatg
    15961 aagatcaata ggacggctac caatcgtaca accacctggc atggatacct tggcatgacc
    16021 cacacgggca aggattggcc ctaatacaac gatggaggcg cgcatcttac tgacatactt
    16081 gtaaggggct tcctcagtga tgtcgccagt agcatccacc ttgacaagat gagcttcctc
    16141 atcaaagtca accttggcat tcaaaccacc aactacctga ttcataataa agacatccga
    16201 caaaatcgga acattctgca agacggtctt tccttcactt gctagaatag tcgctgccaa
    16261 caagggtaag actgcatttt ttgctccctc gatcgtcacg cttcctacca gacgattatc
    16321 gccaccttga accacaattt tatccatact cgtttccttt actcttgatt ttataataat
    16381 cctctaagcg cttcttgcca caaatgatac aggctaataa agaaagaact caggatgtag
    16441 cctatgacaa tgctaaaaaa ggctactaat aaacgaactt ttcttgtatt atcatctgtc
    16501 acttttaaaa ccttctccca tctaacaaga tcctttaaaa ggtaaaaact cacataaata
    16561 aagagcatat gactacttag agtgaataat aattgaacca tttgactatt ataccatctt
    16621 ctctgtttgt gcgctagttt ggaaacttca ctcaaaaatt agggattgtt tttcaagtaa
    16681 tcaatcgcat cttgtagggt tttaacgggc acgattttca tatccgtctt gattgtttta
    16741 gccgcttcta gggctgtttg gtagttgttt ttcgcgtccg gatgcgcctt ttgttcttct
    16801 tcgctaacag ggttatcagg agtaaagaaa atagcagcac ctgccctagc cgaagctaca
    16861 accttcttat caatacctcc aatgtctccc acattaccat cgcggtcaat ggtacctgta
    16921 ccggcaacaa tacgaccatt acgaagatct gggtgagcta tttgagtata gatagctaga
    16981 ctaaacatga gaccagcact tgggccgcca ataccagctg ttgaaaagct aattgggaca
    17041 ttgctgatta cctctgtacg gtcaatcaag ccgattccaa ttccattttt gccattttcc
    17101 aaggtgataa tctttccttc tgcagacttg gtttgcccat cctcttcata ggtgaccttg
    17161 acggaatccc ctaatttttg agaactgacg taatcaatca agtctttgga actatcaaag
    17221 gtctgatcat tgactgctgt gactgtatca gagatattga gaatcccttt aaaggttgaa
    17281 ttatccgtca cattcaaaac ataaactcca aagtacttga gttcgatatc cttaccagct
    17341 gtttttagtc cttgatactt ggccatattt tgcgatgttt gcatgtagaa ttgattgatt
    17401 cgcagaaatt caacatcgga agaaccacct gtagtctcct gagcactacg aatatctgta
    17461 aaaggtgtca accaagcata aatcatatga gctaaagtgg catgttgaac accaaccgta
    17521 acgaattgat aggcaccagc ttccttatct tctgtgtcat ttactttaag gacttggcga
    17581 atatcttccg aaccacctgg aacctctata taataaggca agggcactac aaatgccaag
    17641 aaagtcacaa tcaaggccgc aatgacgtat aagggccatc taatcttttt tttcatttct
    17701 tatttcctcc aaaatactct cgggaacata gcaggcaata tcctgaccaa acttcaaaag
    17761 ctctctaacg cctgatgaac tgatatagag atgttcaggt cgactatgta aataaatagt
    17821 ctctatatca gaagacagct gatgattgta gtaatcaaaa ctggcttcat attgcaaatc
    17881 cgacgcattc ctcaagcctc gcactaggca agtagccccc agtctttttg cgacatcgac
    17941 caccaattta tcatgagaag acacgacttt aacatttccc aaatgtttca cagccttttc
    18001 taacccccgt ttacgatttt caagagggag aaatccttgt ttgtggggat taaaaaaaat
    18061 acccacataa agcttatcaa agagtctgct cgcccgttca atgatatcca gatgcccatt
    18121 tgtcatcgga tcaaatgagc ctgtgaataa gccaatctta tctgacatag actgttacct
    18181 tactaattcc ataaatcttt tccttccaga tacccagaca ggcaatttct tctggaagtt
    18241 caacggcctt atccgtctcg cacacaacca taacatcttc agaaaaaagc tctctctcag
    18301 ccattttttc aatatctgct acgatttgtt ccttggcata gggagggtct aagaaaatga
    18361 ggtcaaattc cccagatacc tgttccaatg ccctttctgc atccatcttg aggagttgaa
    18421 attttccaac ttccttggtc atctggatat tttcagccac gatggtctga gccttacggt
    18481 ctcgctccac caaaacagca ctggacatgc cacgcgatac tgcttcgata gataaaccac
    18541 cactacctgc ataaaggtcc aagactcgtc ccccttcaaa gtagggacca atcatgttaa
    18601 aaatggctcc cctaacctta tccgaagtag gtcttgttgt cttgccttct agtgtcttaa
    18661 ggggacgtcc cccatagatt cctgatatga ttttcatact gtttattata ccaaattata
    18721 gacaaaaaga gaaagaaaac cgaaccttgc ggttcgattc tctacaaaat attttcgtaa
    18781 gtatcgcgga cttcttgagg ccaaacactt gtttgcactt ctccgatgtg tctcttgcga
    18841 agtaggaaca tggccatacg agattgtcca attcctccac cgattgtcaa tgggaatagg
    18901 ccattcaaca aagacttgtg ccattccaat tccaagcggt cttcatcacc tgtaatttcc
    18961 acctgacgtc taagagtttc ttcatctaca cgaattccca tagaagacaa ctcaaaggct
    19021 ccacctaaag actcattcca gacaagaata tcaccattta gacccttgta gccattctca
    19081 gactcgcttg tccagtcatc atagtctggt gcacgtccat cgtgcggttt accatctggc
    19141 aactcgccac cgataccaat caaaaagacg gctccaaatt ctttacaaat cgcattttca
    19201 cgttctttcg gtgtcaagtc tgggtagcgt tctaccaatt cttctgtatg gataaaggtg
    19261 atttgttttg gcaagataga ctcgatgtca tagcgggctt caacagctag ctcagtcagg
    19321 cgaatagcct tataaatctt ctcaactgtt tcttttagat aaacgatgtt acgcttacca
    19381 tttggaataa ccttctccca gtcccactgg tcaacataaa cagagtgggt tgcatccaag
    19441 gaatcctcat ctggacgaag ggctttcatg tggacaaaga gaccctctcc ttcaccaaag
    19501 ccaaaacgag ccaaggtgtg gcgtttccat ttagcaagtg agtgcaccac ttcataagta
    19561 gcatcaggga tttggagaac cttgaccgat actggatttt ccacaccaga caggttgtcc
    19621 tgcattccgt caccgacctt actcaagata ggaccttgaa cttcgacaac ttctagctta
    19681 tctttcaaat actgggtaaa agtgtttttg acaaaggaaa tttcttcttg ttgatggata
    19741 aaacttttct tcatagacaa ctcctcaaaa atttaataaa cgtattatac acctatttcc
    19801 aagaaaagaa aagagaaaat ttaaaaaaaa tcagtgtcac tcaaaacact gatttcatag
    19861 accttttagt cattgcgacc aaagatacgt agaatactta ggaaaagatt gataaaatca
    19921 agatagatgc tgagagccat tgacaccacc cagcctgtcg ctacacgacc ttgtgattgt
    19981 tcataggcga ggcgaatctt ttggttatcc caagcaatca accctgaaaa aaccaaaacc
    20041 atggctacgc taatcatata atcaaagaag ccactagcca agaaaatatt gactaccata
    20101 gcaatcagta aaccaatgag agctgccatc attgctcgac caatcccact caagtctttc
    20161 ttggtaaaaa taccaactgc cgccatgaca aagaagagaa gggcgctcga tacaaaggca
    20221 gataaaactg tacccggagt atagaaagcc accacaaaac taagggtaaa gccgtttaaa
    20281 acggagtaaa gtaaaaatac tggaagagca gctggactat ttcttgaagc catgctactg
    20341 gcaacgaaaa ccaaagccaa ctccgcaaaa gtagcaatgg tcaaccagag acgcccctgc
    20401 atcaacaagt aaaccaactg agactgaaag accgtcaaca taaggcctga taccaaagca
    20461 gatagtccga ttcccagacc aacaaaggca taaaccttag cgtaaaattg attgagacct
    20521 gcacggtcat gtataatagt gtgattcatc cttttctcct tttctgtgaa catctttcct
    20581 tgattataac aaaaaaagtt aaaattagct taaatggaag attaaaatac cggctgcaac
    20641 tgcaacattc aaactctcgg cctgcccctt catgctaata tggaccaact ggtctgcact
    20701 ttcagccata aggggactaa ttccttgacc ctcatttccc ataactagta caaaattttc
    20761 tatagaaggc agttctctgt aatcaacaga atctttagat agggttgttg ctagcactgg
    20821 gatagctacc tttttagttt cgtcaagaag cgcttgacta gtcatccggt aaatgggcag
    20881 atggaaatga ctaccttgca tggaacgtag ggttttgaga ctgtagatgt ctgccgactt
    20941 atctgaaaca atcactcctg taaaacctgc tgcatccgca gttcgaatga tagttcctac
    21001 attaccagga tcttgcacat cttccaaaaa caagaacttg ccctgactca aatcagcttg
    21061 tcctacttct tctttttgaa ccacggcaac aattccctgt ggagtctgag aatccgccaa
    21121 atctagcaaa atatcctctg aaatccagac agtttgcgga aaagcagcta actgatttcg
    21181 ataattttct agggcaaaga ttttctcaat cgtcactcca gcttggacag cttcttcaaa
    21241 caagtgccag ccttcaatca aataggcaga cttgcggtat tttttttggt gtaatttctt
    21301 agcatttttt accacagaat tggcttttga ggttataata gtcatagaaa tattataaca
    21361 caatcaaagg ggtttggtat gcaaaaggtt agaatgattg cccaaggtag ggtgcaggga
    21421 gtcggctttc gttggggtgt ttatagcctg gcccttgaaa tcggtggcat cacaggtcgg
    21481 gtatggaata acgacgatgg cacagtggaa atcttagccc aagcagactc atctgctatc
    21541 atggcaaaat ttatccaaga aatccgaaaa ggaccgacac ctttttcaaa agtaagctac
    21601 ttagatgtca aactaagcaa ctttcctccc tactctgatt ttaaaatcgc aaattaggtc
    21661 tccagaacta ttgtatattt tgtaaaaaaa cagtagaata gaaaggtata atttttaaag
    21721 aaggaataaa aacagtgaaa tctattaaac gttttgcact ctcagctatg ggagtggcta
    21781 tgttgcttgt cttgactggc tgtgtcaatg tcgataaaac cacaggtcag ccaacaggat
    21841 ttatttggaa tacgatcgga gcgcctatgg ctgaagccat caagtacttc gctactgata
    21901 aaggtctagg ctttggtgtc gctatcatta tcgtaaccat tatcgtacgc ttgattatct
    21961 taccacttgg tatctaccaa tcatggaagg caacgcttca ctctgaaaag atgaacgctc
    22021 tcaagcatgt ccttgagcca caccaaacac gtctcaaaga agcaactact caagaagaaa
    22081 aactcgaagc ccaacaagcc ctctttgccg ctcaaaaaga gcacggcatc agcatgtttg
    22141 gtggtgtagg atgtttccct atcctccttc aaatgccttt cttctctgct atctactttg
    22201 ctgcccaaca tactgaaggg gttgctcaag caagctacct aggcattcct ctaggttctc
    22261 caagtatgat tttggttgcc tgtgctggtg tcctttacta tcttcaatcg ctcctttcac
    22321 ttcacggagt agaagatgaa atgcaaagag aacaaatcaa gaaaatgatt tacatgagcc
    22381 cactcatgat cgtcgtcttc tccctcttct caccagctag tgtcacactt tactgggttg
    22441 tcggtggttt catgatgatt ctccaacagt ttatcgtcaa ctatatcgtt cgtccaaaac
    22501 ttcgcaaaaa agtccgtgaa gaactagcca agaacccacc aaaagcaagt gctttctcta
    22561 aaccaagtgg acgaaaagac gttacccctg aacaaccaac tgctatcaca agcaagaaaa
    22621 aacacaaaaa tcgcaacgct ggaaaacaac gttcgagata agaagaaaaa ggcttagctg
    22681 atttgctaag tctttttgca aatcaaaagc ccgatgtttc catcaggttt cttttctatc
    22741 catgtacacg tttcatataa tcttgataac tttcggtatc catgagtttt ttagcgttct
    22801 tgacgcgatc tgctgttggt ggtttgactc cttcgaggga atatggaatt ccaagttcac
    22861 gccacttgaa ctcacccatg gtgtgataag gtagaatttc aaacttatca acatttttga
    22921 gggtcttgac gaacttacca agttcaatca agtcatcatc tctgtctgtc aatcctggaa
    22981 ctagcacgtg gcgaatccag acaggttttc caatatctga tagatactgg gcacaagcca
    23041 agatattttt attagtttgg ctagtgacaa tcttgtgctg ttcttcgttg atttccttga
    23101 tatccaaaag aaccaagtca gtgacagcca tgagtttgtc aaacttctca aggtaacgtg
    23161 gtttattacg gaaaggaaga gcacaggtat ccaaggtaca gtggattcct tgttccttag
    23221 ccttggtgaa gagagcaatc aggaaatcaa tctgcaagag agcttctcct ccactgactg
    23281 taatcccacc cttatttccc cagaaaccac ggtagcgcaa ggcctctgtc aagacatcat
    23341 ctaccgtccg ttcacgtgac ttattggact ccatagccca agtgtctggg ttgtggcaat
    23401 actggcaacg catgtgacag ccctgcaaaa agacaataaa gcgaatacca ggcccatcta
    23461 ctgacccaaa gctttctgtc gaatgcacca ttcctgtcac ttgtccataa tcaattgttt
    23521 cttcagacat atcgttacct tccttgaaaa cgttttatag ttttattata tcacgacttg
    23581 aaggaaaaac aagatttttg cctatttttt agaaagcaat ctgtttttca atttcatttt
    23641 caatctatta tcagattatt cttcaaaatc gaagccatat aaggttgcaa aatagtcctc
    23701 agggcgctct gcacggcgga tttgacgggc tttaccttct tcggtataga ggatttccgc
    23761 agaacgtaat ttggcattat actggtagcc cattgaaaat ccgtgggcac ctgtatcatg
    23821 aatgaccagc aaatcaccga tttctgtatg aggcagttcg cgattgactg caaatttatc
    23881 attgttttca cagagtgaac caaccacatc taccgcttca gctggtccat ctggatgggt
    23941 cacgttgcta atatgatggt aagctccgta catagctgga cgcatgaggt tgactgctga
    24001 ggcatccaca cctagatagg tacggtaggt ttccttctta tgagtcactc ttgtgactag
    24061 agcaccgtga ggtgccagca taaaacgacc caattcggtg aaaatcttga cctgaccaag
    24121 acctgctgac gtaagaactt cttcatacac cttacgaact ccctcaccaa tcaaggcgat
    24181 atcgttcggc tcctggtctg gacgataatt aacaccaata ccgccagaaa gattgataaa
    24241 gtctagccaa atgcccaact tttccttgat ttcaacagcc agttcaaaga gctgacgagc
    24301 caactctgga taatagagat gggtcacggt attggacgct aggaaggagt gaatcccaaa
    24361 agtcttggct cctttttcct tcaagatagc aaaggcttca aagagctggt ccttggtcat
    24421 gccaaactta gcctccccag gattgtccat aatgtctgtc cccagttcaa aaacgcctcc
    24481 aggattataa cgacaagaga tgatttctgg aatgcctgct actctctcca gatgttcaat
    24541 atcttcaaag gcatccaagt taatggtcgc acccaattca cgtgcatagg cgtattcctt
    24601 gtctgacgtg ttgttggaag agaacataat ctcagaaccc agaaagtcca gtttatggct
    24661 catcaaaagc tctacataac tagagcagtc cacaccacaa ccttcttctt ggagaatttt
    24721 caaaatagct ggagttggag tagccttaac tgcaaaatat tccttaaagc ccttgttcca
    24781 cgaaaaggct tggttgacgg ctcttgcctt ctcacgaatc cccttctcat catacaagtg
    24841 aaagggagtc gggaactcgg caacaatcgc ttctaactct tctctattaa taaatggtgt
    24901 tttcataagc ttccttctat tctatttgaa aagaaaggct gggacaatcg ttccaacctt
    24961 tagttctatc tcttatttat cttcgtcaaa gatattgcca acctcaacat cgatggcttg
    25021 gttcttgaca tcaatattgg ttaccttcaa gagtgacttg tagtcaaact gcttttcacg
    25081 ttcttcttgg gcattgtccg caaagaccgc tacacctgcc agttctgagt cgaactcgcg
    25141 caagagacta atcataccgt tgaccgttcc gccacctttc aagaagtcat ccacaatcaa
    25201 gacacggctg cctgccttaa gactacgttt tgaaaggaac attttctcga tacggtcacc
    25261 acttgaacct gaaacatagt tgacgctaac agttgaacct tcggtaattt tcaggtcacg
    25321 gcgcacaatg acaaaagaga cattgaggac attggcaact gcatttgcaa gtggcacacc
    25381 cttagttgct acggtcataa ccgcgtcaat tttttggtcc ataaagcttt tggcaataat
    25441 acgaccaata tttttcaaga tggctggtgt gctaagcaaa tcagacagat agatataacc
    25501 acctggcaag atacggtcac tttctgacaa cttggtacgc aagtcttcaa ccatttcctt
    25561 agcatcctga ctcgaaatag acggtgtgaa gatgacacct ccgccagccc cagtcactgt
    25621 ctggatatga ccgatttcaa tttcctcaaa ggcgcgtttg ataatgacga tatcttctga
    25681 gatggatgat ttagcagact catacttttc agcaaaagta ttgagactag ttagtttata
    25741 aggattatta atcaaatagt tggaaatgac aaccatccga tcacttcttc ttaatttcat
    25801 ttctatttcc tattccattt ttattcaaaa aatcaaaaag caaactaaaa agctggtcgc
    25861 tggtggttca aaacactgtt ttgagattgt cgatagaact gacaaaccct gtaatatacc
    25921 tgcatatata catacgacaa ggcgatacta ccctagtttg aagagatttt cgaagagtat
    25981 tcatttttgt cttttactta ttataccata ttcacataaa aaaacgaaca ttcttatcct
    26041 aaaaaatgct catttttctt aaattatcaa tctaaatctg gtttatagaa ggaacgatta
    26101 tccatagcga agattttatt ggtcatctct cctttatcca ccaaagccag agctgttgac
    26161 atcatcatca tgcttgcatc cagattgtca atcatatgga taatctctgc ctccataata
    26221 cgtggacgga ctggacttcc atactcaagc aagccgtggt gactgaggat gacatgacga
    26281 agcaaaacga cttcttcctt ggtatcatcg atgccgagtt ccataactgt cttggtaatt
    26341 tcgctatcaa tgagagcgat atgtccaaga agattacctc gcactgtgta ctctgtctgg
    26401 tctggccccg tcaactcgat aaccttagct aagtcatgca gcataatccc cgcatagagc
    26461 aggctcttat tgagctgagg ataaacttcg ctaatagcgt ctgccaaacg taccatggtc
    26521 gccgtatgat aagccaaccc cgtttcaaag gcatggtggt tggtcttggc agctggatag
    26581 gagtagaatt ccttatcata cttggtgtag agatttcgga caatccgttg ccagacagga
    26641 ttttcaattt tgaaaatcat ttgcgacatg tagtcacgaa tttccttgac atcaactggt
    26701 gacttgacct tgaaatcggc tgggtcattg ggttcaccag cttgaggcag gcggagagta
    26761 atttgattga cttgaggggt attgttataa acttctcggc gtcctttcat gtggacaacc
    26821 ttacctgcgg taaaggcctc aatgttatga ggttgggcat cccagagctt cccatcaatc
    26881 tcgccactat catcttggaa ggtaaaggct aggtagtttt tcccagctcg agtttgcctc
    26941 aggtcagctg atttgattag gtaaaagcct tcaaatagct catctttttt catgtgacta
    27001 atcttcatat tcttcctcat tttcttgaaa atggagtaga tcaagcgcag gctcaccttc
    27061 tgacaactca atgtgacgga gcgtccgctc gatagctatg gtacgacggt ttaataattc
    27121 atcaatattg ccagaggcat gttggagatg tttttgtgcc ttgaccagaa taccaccaaa
    27181 cttgccaaac tcggtcttga cactggcaag agtcttgctg atatggtcgg cactcttttg
    27241 gatattaagg gtcttgaaac caactgatag ggagttaaga agggctgata gggtacttgg
    27301 tcctgcaacg ataatctgtt cttcccgtct caaatcatca aagaagaccg gattgcgcac
    27361 aatctctgaa taaagacctt ctgtcggaac aaacaagatt ccaaaattgg ttgtccgagg
    27421 cggtgctatg tacttgctct tgatatcctt ggcaaagcgc ttgacgcttg ctaggagtga
    27481 cttacgacag cgttcaatct catccttgtc acctgtctca taggcttctt ccaagcggta
    27541 ataatctgcc agtggaaact tagagtcaat tggcagatag acgtattctt ggtcgccttg
    27601 tccgggtaac ttgatggcat actccactcg ttcactagag ttttcaaccg ttgcgtattc
    27661 tcgttcgtac tgggcaggtg tcatgatgtc ttcaataatt tgccccagtt gcaattctcc
    27721 cagaatacct cgcgtcttgg ttccagagag aaccttgtta agagctccga catcacgggc
    27781 aactgtctgc atttctccaa ggccacgatt gacagactcc agttgtttag aaactgtttc
    27841 aaaggaagcc tgtaagcgtg tctgcaaggt cttttctagt ttttcctcga ccgtctggcg
    27901 catttgttcc aaacgttgct catttgattc ctgcaaggct tggagacgtt ggtctgtctt
    27961 atctctagtt tggaggagat tatctgtcat ttcttgacgg acttgggtca ggccttggtg
    28021 caattcaatc cgcacttctt gcaaacggtc gctgacagcc acttccaaat ctttttggtc
    28081 taactggctg gcttgtctgg cttggtcaaa gcggtaatcc aactggtctg acaaatgatc
    28141 tgcctgatcc tccaagctct tacttaagtg tttctcctgc ctatcctgcc tttgccaaat
    28201 cagaaagaga ccagctaggt tggcaattaa taatagaata agtaaacttt ccatcctacc
    28261 tcctgtcctt gctatgcagt acgaccacat aaccatctgg gcaagttacc gacacttccc
    28321 tatctatata ttcgttagaa gcgtacactt ttttaaagaa aaaattctcc tctgtcaact
    28381 catacttagc tccaagaata gtcagctggc tatcccgaac tggcataaag gctagatagt
    28441 cgtagtctga acgaggttct agctgactgg tcccttctga acaataggca atcaaatttt
    28501 gcccatcctc aatttctatt tgacgcatat agggtgccaa cttaggattg ctaggtagaa
    28561 agacattggc caacatatgg tcaatacggc cacccaaggc accgaaaata gtgacctgag
    28621 cctgaggatt ttgttcaaag atggttaaga gagccaattc cagatctgta tcatcctttt
    28681 ctggtcgggc ttggacaaaa tactgggcac gtttttgaat cacctgtcgc tcttcttccg
    28741 tcacagaatc aaaatctccg actgctagag caagaggtaa gtcttcttcc aagacccaga
    28801 gcgagcctcg atccacccca acaaaagcat caaaatctgt ccgataatga ccgcggtttc
    28861 cgcctgcaaa aactgcaacc ctagtccagt tgttttctga gagtttgtac tcgctcattg
    28921 acttctccct taaagacata ggaacctgct acaaaaacag tcgcaccagc ttctttggct
    28981 tgagcaatag tttggtcatc aatcccacca tccacttcga tttcaaagtt caaacctttt
    29041 tcctcacgaa gagcaaccaa ctcacgaacc ttatccatgg tttctggcag aaaggcttgc
    29101 ccaccaaaac ctggattaac cgtcatgact aaaacttggt caactagatg aaggacgtgc
    29161 ttgatggctt caactggtgt gccaggattg ataacgactg aaggcttaac tccgagtgaa
    29221 cgaatttttt ggagggcgcc atgaatatga ggtgttgctt ctacatggat actgatgatg
    29281 tctgcacctg cacgcgcaaa atcttccaga tgatgctcag ggtttgacac catcaagtgg
    29341 caatcgaaaa ccatcttact atgaggacga aggctctcga ccacacctgc accaaaactg
    29401 atttgcggta caaaatgact gtccatgata tcgatatggg catattctgc cccagttgct
    29461 tctagacgtt tgatttcacg ttcaaagttg gcataatctg ctgccagaat tgacggagca
    29521 atcttgtatt gagacatagg tttctcctta ttttggaatt tttttgctga cttttttata
    29581 ggtttctcta cgattttcaa tttcactaag gaattgcagg taattgtcaa aacggaaggt
    29641 tgcaataaca ccctcttcaa cagctggttt gacggcacaa gacggctcat gggtatgggt
    29701 acaagtacgg aacttacaat ctcggctaac agtagcaatc tctgggaaag cctgattgag
    29761 gtcttcagcc cttgatactt catagtccaa ggatgaaaat cctggtgtat ctgcgatttt
    29821 acccccgttg agattgtaaa aactaacagc tcgagtggta tggcgaccgc gacctagact
    29881 gtctgaaatt tctcccgttt caagattgag gtctggtgcg attttattga gaagagttga
    29941 cttcccaaca cctgtctgcc ccataaagac cgtaaccttg cctgttaaca aagacaggag
    30001 ttcctcttta ctggtcacaa agtcatagcc gatgtcacca taggtctgct ggtaaaaatc
    30061 cagttctccc ctatcttcca acaaatccat tttggaaata tagacaatgg gatggatgcc
    30121 cttgtgctcc aaaagaacca agaaacgatc cagcaaattg ctgttaaaat caggttcctt
    30181 gacggacatg attactacag cttgatcgat attgacaata ggcggacgaa ccagactgtt
    30241 tttccgttcg tgaattttga ggatatagcc ttctgaattt tcctcggcag agaaatctac
    30301 ccagtcccca acataagggg tatggccttt tttacggaaa ttcccacgcg cgcgtgtttg
    30361 ataaacctgg ccatcactct ccacatagta gaaacctgcc aaggctttaa tgatttgtcc
    30421 ctgcatctta gagtccttgc cctttaagtg cgtctgctag accggcaaat tctgccaagc
    30481 tgagagcttc cccacgcaca cttggtgaca agcctgcctg gtccaaagcc ttggtcagct
    30541 tgtccttgac ctcttcagtc ttaccaaagt aacctgtcaa gttattccac aaggtcttgc
    30601 ggcgatgggt aaaactagcc ttggaaacct taaagaaaaa gttctcatct tctactgcta
    30661 cggctggctc tggacgacgc accattttca agatggctga atccacattt ggtgctggca
    30721 caaagaccgt acgaggcacg ataaaggcaa ccttggctgt catgtaatac tgcacggcga
    30781 tagacaagct accgtaagcc ttggtgttag gctgggctga aatgcggtcc gctacttctt
    30841 tctgcatcat gaccacaaac tcacaaaaag gaatgccact ctcaatcaag tgcatgagaa
    30901 taggcgtcgt gatgtagtaa ggcaaattag ccactacctt gattggcagg ttaggatttt
    30961 taaaattttg gatatgttgc gccaaatcaa ccttgagaat atcttcgtta actacagtca
    31021 cattatcaaa atcacgcagg gtatctgcca aaattggcac caaacggtgg tcaatctcaa
    31081 aagccatgac ttgggctgca cgctcagcca gaaactccgt caaggcacca atacctggcc
    31141 cgatttcgat gacattgacc tggtcatcaa tttcagccgt atccacaatt ttttgaagga
    31201 tattggtatc cgtcagaaaa ttttgcccga aggacttttt aaaggtaaaa ccgtgacgct
    31261 ccagcactgc cttggtcacg ctataatctg caattctcat ctattctctt ttctattatc
    31321 tgttactact attgtaacac attccccttg tattttggga atgaaaatca taccaaaaaa
    31381 ctatctttcc tcatgaagaa agatagtctt ggaaatcttt aaaagtggcc ttaacagttc
    31441 tctcgaaaca tgcgttcata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg
    31501 ccgtactcaa gtacagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
    31561 tcaaaaaaat cagcttcttg ataacttcta ttttcgggta gggtcaaatc cacatcctcc
    31621 tccacatcat ccactgtcag ttcaaccgtt tgaggtaaat ttttcaaacg ataatgcttt
    31681 tgcctttgcc cttcaatact agcaaaatca agcaaatagc catgcactag gatttgaacc
    31741 aaaaggagat gattggtcat attttccatg atgaggatat cttctaaacc acctctggca
    31801 ctaggataat cagataccct gcgaatacgg attttttcac acatgagcaa gtttcctcat
    31861 atcaatgatt tcatcagcct tattccagac taggggatta tgggtcgcaa tgatgataat
    31921 tcgattttca tctttcaaat ccaccaagag attcataacc tcctctgaat tttcaggatc
    31981 aagagctgct gttggttcat ctgccaaaat caagggtgga tttttcaaaa tagtcttagc
    32041 aagggcaact cgttgggcct ctcccccaga taaagtatag attttttgtt ctaaatccaa
    32101 ataccctaga ttaacttttt ctaaagcccc cacttgcttt tccaaacgtt ctacttttga
    32161 gattttctga ccaacaaaac ccaaatccaa attttctttg attgattggt tttctaagag
    32221 gccgaaattt tgaaagagat agcccatctg gtctcgaaaa tactcacgag tgggaatggt
    32281 ttttaaatct ttcccctgat agagaaccct tccaccatct atcttttcta gctttcccaa
    32341 gatattcagc agcgtcgtct ttccgcttcc actctttccg attaaggcat aaaccttgcc
    32401 cttctccagc ttgagattca aaccagagaa aatcgcgcgg tcattaaatt tcttttccaa
    32461 tccttgaata tcaatcatct tattttcctt tcaatactgc catgctacca gcttcttctt
    32521 ttttgtcctg ccttactaaa atcaagaggg cgttaagcgt aaacaaagct acaactagag
    32581 cgctaatcaa accatctctt gtcaaaatac tagataggac taggccaagc aagagaactc
    32641 ctccttgcgc cagtaaatac ttgccatgaa gctcatagat tgtcatacca gcaagacgtt
    32701 taatcataag ctcccgtctg aactgctcaa aatagagaag attcatggaa tcaaataaca
    32761 agatagccgt agacagggtc aaaatcgtcc caataaggag agagtaaaac tctacccgtt
    32821 tgtcatttag taccttggca aaaaatagct ggctttttac caagtaagaa accttgtgat
    32881 acagaccttg ctcttttaga gctgtgatgc tgtctccata tcgatctagt ttcaaggcac
    32941 tattagccgt agttccccac aacatccctg caacaggtct tgttccagtc gcttgcggcg
    33001 ttagaactac aataatcgga tcttttaggt actggcgtgt tgtcttgtac ccatcattat
    33061 agaggaaacg ttcctgtcct gtttctgtaa aagctagact tacctgtggg aggtagtatt
    33121 tctgactcgt cacttctaca ctttcagatg aaaagttttg caggtaatct gtaaacaatc
    33181 tttggtagta ggtagactgc tctcgcaagc tctcaggcaa gattagccca aactctccct
    33241 cagacaagtt ttgcatcttg tccataaact ctgaagaaac ggtaatcttt tcttctatca
    33301 gatagcgtgg tgagacatag ataacattcc ctgacggtgt gtagtcactg agacgattgc
    33361 catctaggtc cacttctgct ccatctgaga aattgtcaac attgctcata atataaaaag
    33421 agtctgtatt ggctaaccgt tcttcagtaa atgtctgcca ctcacgatta tccttacgcg
    33481 ttccttcttc atcggcaaat gcactagacc aaccaaagga tagacggtaa cggtctgagg
    33541 actggctcca tttattgcta gctctctcca tttcctgcat ttcacggtag tggggtagga
    33601 gagctgtcgc actcgatccg accaccaata cagctaagag ttgccccacc atcatcaatg
    33661 tcatcatacg tttgagaggg agtttccctt t
//
LOCUS       DAVHSL010000022        33120 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000022 DAVHSL010000000
VERSION     DAVHSL010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.022"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            25..888
                     /locus_tag="VVR39_001031"
     CDS             25..888
                     /locus_tag="VVR39_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6030537.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDLYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDAV"
     gene            1271..1891
                     /locus_tag="VVR39_001032"
     CDS             1271..1891
                     /locus_tag="VVR39_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030538.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            1978..2421
                     /gene="tsaE"
                     /locus_tag="VVR39_001033"
     CDS             1978..2421
                     /gene="tsaE"
                     /locus_tag="VVR39_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU6030539.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2411..2929
                     /locus_tag="VVR39_001034"
     CDS             2411..2929
                     /locus_tag="VVR39_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030540.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2937..3953
                     /locus_tag="VVR39_001035"
     CDS             2937..3953
                     /locus_tag="VVR39_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU6030541.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4038..5294
                     /locus_tag="VVR39_001036"
     CDS             4038..5294
                     /locus_tag="VVR39_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU6030542.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5349..6515
                     /gene="recA"
                     /locus_tag="VVR39_001037"
     CDS             5349..6515
                     /gene="recA"
                     /locus_tag="VVR39_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU6030543.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6822..8192
                     /locus_tag="VVR39_001038"
     CDS             6822..8192
                     /locus_tag="VVR39_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6030544.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVFFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8568..9524
                     /gene="lytA"
                     /locus_tag="VVR39_001039"
     CDS             8568..9524
                     /gene="lytA"
                     /locus_tag="VVR39_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU6030545.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9883..10044
                     /locus_tag="VVR39_001040"
     CDS             9883..10044
                     /locus_tag="VVR39_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6030546.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10031..10237
                     /locus_tag="VVR39_001041"
     CDS             10031..10237
                     /locus_tag="VVR39_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030547.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            10283..10642
                     /locus_tag="VVR39_001042"
     CDS             10283..10642
                     /locus_tag="VVR39_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030548.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKETVLG"
     gene            10771..11196
                     /locus_tag="VVR39_001043"
     CDS             10771..11196
                     /locus_tag="VVR39_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030549.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            11604..12188
                     /locus_tag="VVR39_001044"
     CDS             11604..12188
                     /locus_tag="VVR39_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030550.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            12192..12389
                     /locus_tag="VVR39_001045"
     CDS             12192..12389
                     /locus_tag="VVR39_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030551.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEKSEALENMILQYLGEDDAS"
     gene            12379..12930
                     /locus_tag="VVR39_001046"
     CDS             12379..12930
                     /locus_tag="VVR39_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030552.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLNEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLRLAS"
     gene            12989..13249
                     /locus_tag="VVR39_001047"
     CDS             12989..13249
                     /locus_tag="VVR39_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030553.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(13975..14371)
                     /locus_tag="VVR39_001048"
                     /pseudo
     CDS             complement(13975..14371)
                     /locus_tag="VVR39_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14496..14954
                     /locus_tag="VVR39_001049"
     CDS             14496..14954
                     /locus_tag="VVR39_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU6030554.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14967..15575
                     /locus_tag="VVR39_001050"
     CDS             14967..15575
                     /locus_tag="VVR39_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030555.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            15646..15978
                     /locus_tag="VVR39_001051"
     CDS             15646..15978
                     /locus_tag="VVR39_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030556.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            15989..17404
                     /gene="ply"
                     /locus_tag="VVR39_001052"
     CDS             15989..17404
                     /gene="ply"
                     /locus_tag="VVR39_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU6030557.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            18285..19001
                     /locus_tag="VVR39_001053"
     CDS             18285..19001
                     /locus_tag="VVR39_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6030558.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            19125..19574
                     /locus_tag="VVR39_001054"
                     /pseudo
     CDS             19125..19574
                     /locus_tag="VVR39_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            19613..20434
                     /locus_tag="VVR39_001055"
     CDS             19613..20434
                     /locus_tag="VVR39_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030559.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            20441..21472
                     /locus_tag="VVR39_001056"
     CDS             20441..21472
                     /locus_tag="VVR39_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6030560.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARTLLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            21538..21900
                     /locus_tag="VVR39_001057"
     CDS             21538..21900
                     /locus_tag="VVR39_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU6030561.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            21897..22400
                     /locus_tag="VVR39_001058"
     CDS             21897..22400
                     /locus_tag="VVR39_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6030562.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWNTCPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLNFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            22514..22960
                     /locus_tag="VVR39_001059"
     CDS             22514..22960
                     /locus_tag="VVR39_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6030563.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            22965..23639
                     /locus_tag="VVR39_001060"
     CDS             22965..23639
                     /locus_tag="VVR39_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030564.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            23800..23991
                     /locus_tag="VVR39_001061"
     CDS             23800..23991
                     /locus_tag="VVR39_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU6030565.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            24276..24575
                     /locus_tag="VVR39_001062"
     CDS             24276..24575
                     /locus_tag="VVR39_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU6030566.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            24572..24889
                     /locus_tag="VVR39_001063"
     CDS             24572..24889
                     /locus_tag="VVR39_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU6030567.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            24905..25531
                     /locus_tag="VVR39_001064"
     CDS             24905..25531
                     /locus_tag="VVR39_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU6030568.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            25564..26325
                     /locus_tag="VVR39_001065"
     CDS             25564..26325
                     /locus_tag="VVR39_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6030569.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGDDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            26403..26798
                     /locus_tag="VVR39_001066"
     CDS             26403..26798
                     /locus_tag="VVR39_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6030570.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            27068..27352
                     /gene="groES"
                     /locus_tag="VVR39_001067"
     CDS             27068..27352
                     /gene="groES"
                     /locus_tag="VVR39_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU6030571.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            27368..28990
                     /gene="groL"
                     /locus_tag="VVR39_001068"
     CDS             27368..28990
                     /gene="groL"
                     /locus_tag="VVR39_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU6030572.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            29128..29883
                     /locus_tag="VVR39_001069"
                     /pseudo
     CDS             29128..29883
                     /locus_tag="VVR39_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(30323..30856)
                     /locus_tag="VVR39_001070"
     CDS             complement(30323..30856)
                     /locus_tag="VVR39_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU6030573.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(30945..31721)
                     /gene="recX"
                     /locus_tag="VVR39_001071"
     CDS             complement(30945..31721)
                     /gene="recX"
                     /locus_tag="VVR39_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU6030574.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVEQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            31759..33114
                     /gene="rlmD"
                     /locus_tag="VVR39_001072"
     CDS             31759..33114
                     /gene="rlmD"
                     /locus_tag="VVR39_001072"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6030575.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKGFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLDYEFSL
                     SPRAFYQLNPEQTEVLYSEVVKALDVSKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT        10199 a         5720 c         7245 g         9956 t
ORIGIN      
        1 aaataggaag gtttattatc tttaatgaat acactcgcag agaaattcag attgaaaaga
       61 aaagagttga gactctccca acaaactctt gcagaaggaa tttgtgaaca aagccagatt
      121 agtaaaattg agagagggca tttcattccc tccgcagacc ttttgttcaa actctctcaa
      181 cgacttgaag taccattaga ttattttttt aatgaacaaa ttgaaattaa atctaacctc
      241 tctaatttca agcaattgtc tgctcgacta ttagacgata gaaattatga cgatttggaa
      301 tatatttata gaatagagat tgaacgaagt acttttctaa cactagaaga ccgaacttac
      361 cttgaatgga ttaaagctat tattgactta tatcaatatg acagtaagtg tgaggcaatt
      421 tcttcattgg aaaatatatt attaaaagtc tcttcaaata ctctgattta tttaaaggcg
      481 ttgaatactc tatctaattt ctattcctta gtgggtcgtg aacaagaata tgaggcaaac
      541 tactctcatt taatagagtt gtatcagaca aaaaatttgg accatcaaga gtttttattt
      601 ggctacatca gagttcgtta caactacgct cactacctag tatcaaagga aaaatataat
      661 gaagccatcc aagaagctct tgaaacgatt gaactctgta aacaaagaca gacaagctac
      721 caattggctc ctctacttat tcttgtagga aatgctggag ccaaatttct agacagagaa
      781 caagtcaaaa attattatat agaagcaaga gagctatgca agatttataa caatccttta
      841 atgctgatga agatagaaaa ttatttgaag gaactagatg ctgtttagtt tatcttgata
      901 ttggagtgtt acttaaacat taaatagcct gtaaggctga tagttagatt aatactatca
      961 gccttataat tatgtgactc tgagtccgtc tcgctccgtg aggtgcgaga caaaacaacc
     1021 acccgtttga cggattttca tgatttcaaa tttatattct tcgaaaatct cttcaaacca
     1081 cgtcagctct atctgcaatc tcaaaacagt gttttgagca acctgtggct agctacctag
     1141 tttgctcttt gattttcatt gagtattagt ctctagtgtt tgtttagcgt cttaaagaga
     1201 catttgagaa gattagaaac agttctctct tttctcctag tataatgatt ggtaggaagg
     1261 gagagagaag atgaaatcaa tgagaatctt atttttgtta gctttaattc aaatcagttt
     1321 gagtagctgt ttcctatgga aggaatgcat cttgtccttt aaacaaagta cagctttttt
     1381 catcggaagc atggttttcg tttcaggaat ctgtgctgga gtaaattatc tttatacccg
     1441 taagcaagaa gtccatagtg tcctagccag taagaagtcg gtgaagcttt tttacagtat
     1501 gttactctta attaatttgt taggagctgt tcttgttttg tcagataact tgttcatcaa
     1561 aaatacgctg cagcaagaat tagttgactt tttattgcca tccttctttt tcctatttgg
     1621 gctagatttg ctgatttttt tacccttgaa aaaatacgtg cgcgattttc ttgctatgct
     1681 agacagaaaa aagacagtgt tggtgactat tttagcaaca cttcttttct taagaaatcc
     1741 aatgaccatt gtctcacttc tgatttatat tggactgggc ttgttttttg cagcctatct
     1801 tgtcccaaat tcggttaaga aggaagtatc cttttatggt catattttcc gagatcttgt
     1861 attggtcatt gttacgctca ttttctttta gagaaagcct gtttttgtat ggatgttatg
     1921 atgataagtt tagtaggaaa atagacacaa aagaaaagtt tttggtataa taagagtatg
     1981 tacacaaaaa atgaagaaga gttgcaagcc ttaggggagc gtttgggcca tctattagca
     2041 aagaatgatg ttttaatctt aactggagaa ctgggtgcag gtaaaacgac ctttactaaa
     2101 ggacttgcaa aaggattaca gatttctcaa atgattaaaa gtcccaccta tactatcgtg
     2161 agagagtatg aaggtcgact tccactttat cacctagatg tttatcgtat tgaaggagat
     2221 gctgattcta tcgacttgga tgagtttatc tttggtggcg gcgtgactgt tattgagtgg
     2281 ggaaatctct taggagatgc cttgccagat gcttatttag aattggaaat tctaaaagaa
     2341 gcagatggac gccgtttaaa ttttcaggca aagggtttgc gtgctgagaa attgttagag
     2401 gagcttcaat atggagtatg aattgctcat tagggaagca gagcccaaag atgcagctga
     2461 attagtggcc tttttaaatc gtgtgagttt ggagacagac tttaccagcc tagacggaga
     2521 tggtattctc ttgactagtg aggagatgga aatattcctc aacaagcaag ctagttcgga
     2581 caatcagata accttacttg cattcttaaa tggcaaaatt gctggtattg taaatattac
     2641 agctgatcag cgtaagagag tccgtcatat tggagatctc ttcattgtga ttggaaaaag
     2701 atattggaat aatggcttgg gaagtttgtt gctagaagaa gcgatagagt gggcacaagc
     2761 aagtggcatt ctgcgtcgtc tccaactgac tgtccaaact cgtaatcaag cagcagtcca
     2821 tctttatcaa aagcatggct ttgtcattga aggtagccaa gagcgtgggg catatataga
     2881 agaagggaaa tttatcgatg tttacttgat gggtaaactg ataggttagt agaaatatgg
     2941 ttaaaaaaat tattggaatg gtgctagctt tactttctgt aactgtagta ggagtaggtg
     3001 tttttgctta tactatttat caacaaggga cagaaacctt agctaaaacc tataaaaaaa
     3061 tcggcgaaga aaccaaggtt attgaagcga ctgaacctct aaccattctg ttaatgggag
     3121 tggacaccgg aaatgttgaa cgaactgaaa cttgggtcgg tagaagtgat agcatgatct
     3181 tgatgacagt gaatcctaaa acgaaaaaaa caacaatgat gagtttagag cgggatattc
     3241 tgacgcgcat tgaatcaggg aatggtcagg ctcatgaagc gaaactgaac tcagcatatg
     3301 cagatggtgg agcagagctt gctatagaaa ccattcaaaa aatgatgaat atccatattg
     3361 atcgctatgt gatggtcaat atgagagggt tgcaaaaact agtggatgca gtaggaggta
     3421 ttacagtcaa taatatccta ggtttcccaa tttctatcag tgaccaagaa gaatttaata
     3481 ccatttctat cggtgttggg gagcaacata ttgggggaga agaagcccta gtctatgcac
     3541 gaatgcgtta ccaagatcct gagggggatt atggtcgtca aaaacgtcaa cgtgaagtta
     3601 ttcaaaaagt catggaaaaa gctctcagtt taaatagcat tggtcattat caagagattc
     3661 taaaagcttt gagtgacaat atgcagacca atattgattt gtctgcaaaa agtatcccta
     3721 acttgctagg ctataaagat tcatttaaaa ccattgaaac tcagcagttg cagggtgaag
     3781 gagagatact tcaaggtgtt tcttaccaga ttgtttcgag agcacatatg ttggaaatgc
     3841 aaaatatact ccgacgttct ttgggacaag aagaagttac tcagcttgaa accaatgcgg
     3901 ttttatttga agatttattt ggcagagcac ctgttggtga tgaagataat taacttttga
     3961 tacaaataaa aaaatcaatc gtaggaaaat tcctgcgatt ttttcaaaaa aatacgaata
     4021 gataggtagg aggaaacatg aaagcagaaa tcattgctgt tggaacagag attttgacag
     4081 ggcagattgt caacaccaat gcccagtttt tgtcggaaaa actagctgag attggggtag
     4141 atgtatattt tcagacggct gtaggagaca atgaagttcg tctcttgtct ttgcttgaga
     4201 ttgccagtca acgtagcagt ctggtgattt tgacaggcgg tttggggcca actgaggacg
     4261 acctaaccaa acaaacccta gctaaatttt tagggaaagc attagtcttt gatcctcagg
     4321 ctcaggagaa gttggatatc ttttttgccc tgcgaccaga ctatgcccga acaccgaata
     4381 acgaaagaca agctcaaatt gtagaaggag cgattccact gccaaacgaa acaggactgg
     4441 ctgttggagg aaaattagaa gtagacggag tgacctatgt cgtccttcca ggtccgccaa
     4501 gtgaattgaa acccatggtc ttaaaccaac ttctacccaa gttgatgaca gggagcaagc
     4561 tgtattcccg agttcttcgt ttctttggga ttggcgagag ccagttggtt acgattttgg
     4621 ctgatttaat tgataatcag atcgatccta ccttggcccc ttatgccaag acaggagaag
     4681 tcactctacg tctgtcaaca aaggctagca gtcaagaaga ggcgaatcaa gcgctggata
     4741 tcttggaaaa tcaaatcttg gactgccaga ctttcgaagg aatttcttta cgagactttt
     4801 gctatggtta tggggaagaa actagtttag ccagcattgt ggtagaagaa ctgaaaaggc
     4861 aagggaaaac catcgcggct gcagagagtt tgacggcagg tcttttccaa gctaccgtgg
     4921 cgaatttttc tggagcttca agtatattta agggtggttt tgtgacctat agcttggagg
     4981 aaaaatcaag gatgttggat attcctgcca agaatttgga agaacatggt gtggtgtctg
     5041 aatttacagc tcagaagatg gctgagcagg cacgaagcaa gacccagtct gattttggaa
     5101 ttagtttgac cggagtggca ggaccagata gcctagaagg acacccagtt gggacagtct
     5161 tcataggctt ggcgcaagag caaggaactg aggttatcaa ggttaatatt ggaggcagaa
     5221 gccgagcaga tgtacgtcat attgcggtta tgcatgcctt taacctagtt cgcaaggctt
     5281 tattaagtga ctaacttttg atataatagt agataggtct gaggatcatt agaatgtagg
     5341 agaatagaat ggcgaaaaaa ccaaaaaaat tagaagaaat ttcaaaaaaa tttggggcag
     5401 aacgtgaaaa ggccttgaat gacgctctta aattgattga gaaagacttt ggtaaaggat
     5461 caatcatgcg tttgggtgaa cgtgcggagc aaaaggtgca agtgatgagc tcaggttctt
     5521 tagctcttga cattgccctt ggctcaggtg gttatcctaa gggacgtatc atcgaaatct
     5581 atggcccaga gtcatctggt aagacaacgg ttgcccttca tgcagttgca caagcgcaaa
     5641 aagaaggtgg gattgctgcc tttatcgatg cggaacatgc ccttgatcca gcttatgctg
     5701 cggcccttgg tgtcaatatt gacgaattgc tcttgtctca accagactca ggagagcaag
     5761 gtcttgagat tgcgggaaaa ttgattgact caggtgcagt tgatcttgtc gtagtcgact
     5821 cagttgctgc ccttgttcct cgtgcggaaa ttgatggaga tatcggagat agccatgttg
     5881 gtttgcaggc tcgtatgatg agccaggcca tgcgtaaact tggcgcctct atcaataaaa
     5941 ccaaaacaat tgccattttt atcaaccaat tgcgtgaaaa agttggagtg atgtttggaa
     6001 atccagaaac aacaccgggc ggacgtgctt tgaaattcta tgcttcagtc cgcttggatg
     6061 ttcgtggtaa tacacaaatt aagggaactg gtgaccaaaa agaaaccaat gtcggtaaag
     6121 aaactaagat taaggttgta aaaaataagg tagctccacc gtttaaggaa gccgtagttg
     6181 aaattatgta cggagaagga atttctaaga ctggtgagct tttgaagatt gcaagcgatt
     6241 tggatattat caaaaaagca ggggcttggt attcttacaa agatgaaaaa attgggcaag
     6301 gttctgaaaa tgctaagaaa tacttggcag agcacccaga aatctttgat gaaattgata
     6361 agcaagtccg ttctaaattt ggcttgattg atggagaaga agtttcagaa caagatactg
     6421 aaaacaaaaa agatgagcca aagaaagaag aagcagtgaa tgaagaagtt acgcttgact
     6481 taggcgatga acttgaaatc gaaattgaag aataagctgt taaagcagtg gagaaatccg
     6541 ctactttttc gatttttgat tcaagttttt agattatata tagtagcttg aaataagata
     6601 tgaacaactt tattaggaaa gtcaaattaa tttctagaaa tgttttagca gctacagcgt
     6661 actattccaa actcaaccaa ctataataga tcgaaactag aatagtacac atctacttct
     6721 aaaacattgt taaaaatcga tttgactttc cttatttcat tccgctatat ataagtttgc
     6781 tgtttcttgt cgctcctcta ggaagctgat ataatagctt tatgaataaa aaacgaacag
     6841 tggacctgat acatggtccg attcttccct cgctcttaag cttcaccttt ccaatcttgc
     6901 tatcaaatat ttttcaacag ctctataaca ctgctgatgt cttgattgtt ggacgatttc
     6961 ttggtcaaga atccttggct gcagtaggag cgacgacagc gatttttgac ctgattgtag
     7021 gttttacact tggtgttggc aatggcatgg ggattgtcat tgctcgttat tatggagctc
     7081 ggaatttcac taaaatcaag gaagcagtag cagccacttg gattttaggt gctcttttga
     7141 gcattctagt tatgttgctg ggctttcttg gtttgtatcc tctcttgcaa tacttagata
     7201 ctcctgcaga aattcttcct caatcttatc aatatatttc tatgattgtg acctgtgtag
     7261 gtgtcagctt tgcttataat ctttttgcag gcttgttgcg gtctattggt gacagtctag
     7321 cagccctggg atttctgatt ttctctgcct tggttaatgt ggttctggat ctctatttta
     7381 ttacgcaatt gcatctggga gttcaatccg caggacttgc taccattatt tcgcaaggtt
     7441 tatcagcggt tctctgcttt tattatattc gtaaaagtgt gccagaactc ttgccacagt
     7501 ttaaacattt caaatgggac aaaagcttgt acgcggatct cttggagcaa ggtttggcta
     7561 tgggcttgat gagttcaatt gtatctatcg gcagtgtgat tttacagttt tctgttaata
     7621 catttggtgc agtgattatt agtgcccaga cggcagctcg acgcattatg acctttgccc
     7681 ttcttcctat gaccgctatt tctgcatcaa tgacgacctt tgcttctcag aatctaggag
     7741 ctaagcgacc tgaccgcatt gttcaaggtc ttcgaatcgg cagtcgttta agtatatcct
     7801 gggcagtttt tgtttgtatt ttcctctttt ttgccagtcc agctttggtt ttcttcttgg
     7861 ctagttcgac agatggttac ttgatagaaa atggaagtct ctatctgcaa atcagttcag
     7921 ccttttatcc cattttgagc ctcttgttga tttatcgcaa ttgcttgcag ggcttggggc
     7981 agaagatcct tcctctagtt tctagcttta ttgaactaat cggaaaaatc gtttttgtgg
     8041 ttttgattat tccttgggca ggatataagg gtgttatcct ttgtgaacct cttatctggg
     8101 ttgccatgac agttcaactg tacttctcac tattccgtca tcccttgata aaagaaggaa
     8161 aggcaatttt ggcaaccaaa gtgcaatcct agttggattt actgaataaa atccatttcc
     8221 tctagtgaac atcgaaaaaa cttgtgttct cttctttagt ttggtgttga aaatagttta
     8281 acagactttt gacttctttt atatgatata ataaagtata gtatttatga aaaggacata
     8341 tagagactgt aaaaatatac ttttgaaaag ctttttagtc tggggtgtta ttgtagatag
     8401 aatgcagacc ttgtcagtcc tatttacagt gtcaaaatag tgcgttttga ggttctatct
     8461 acaagcctaa tcgtgactaa gattgtcttc tttgtaaggt agaaataaag gagtttctgg
     8521 ttctggattg taaaaaatga gttgttttaa ttgataagga gtagaatatg gaaattaatg
     8581 tgagtaaatt aagaacagat ttgcctcaag tcggcgtgca accatatagg caagtacacg
     8641 cacactcaac tgggaatccg cattcaaccg tacagaatga agcggattat cactggcgga
     8701 aagacccaga attaggtttt ttctcgcaca ttgttgggaa cggttgcatc atgcaggtag
     8761 gacctgttga taatggtgcc tgggacgttg ggggcggttg gaatgctgag acctatgcag
     8821 cggttgaact gattgaaagc cattcaacta aagaagagtt catgacggac taccgccttt
     8881 atatcgaact cttacgcaat ctagcagatg aagcaggttt gccgaaaacg cttgatacag
     8941 ggagtttagc tggaattaaa acgcacgagt attgcacgaa taaccaacca aacaaccact
     9001 cagaccacgt tgacccttat ccatatcttg ctaaatgggg cattagccgt gagcagttta
     9061 agcatgatat tgagaacggc ttgacgattg aaacaggctg gcagaagaat gacactggct
     9121 actggtacgt acattcagac ggctcttatc caaaagacaa gtttgagaaa atcaatggca
     9181 cttggtacta ctttgacagt tcaggctata tgcttgcaga ccgctggagg aagcacacag
     9241 acggcaactg gtactggttc gacaactcag gcgaaatggc tacaggctgg aagaaaattg
     9301 ctgataagtg gtactatttc aacgaagaag gtgccatgaa gacaggctgg gtcaagtaca
     9361 aggacacttg gtactactta gacgctaaag aaggcgccat ggtatcaaat gcctttatcc
     9421 agtcagcgga cggaacaggc tggtactacc tcaaaccaga cggaacactg gcagacaagc
     9481 cagaattcac agtagagcca gatggcttga ttacagtaaa ataataatgg aatgtctttc
     9541 aaatcagaac agcgcatatt attaggtctt gaaaaagctt aatagtatgc gtttttttgt
     9601 ggagatattt ccttcaatgt ttgctactat attaaacaaa aatcagaaag caaactagaa
     9661 agttatgctc aaataaaatc taaatttgac aatgtaaacc gagtcggata gctttaagta
     9721 ctgttttgag gttgaagata cgatttttga taggaactca tcaattttag atttttaagc
     9781 agcatcaata aattgcttcc ttgttttgtc ataatttttt tatttaaaaa attatgacaa
     9841 gagtgtgcta ttctttttat gagaggtgta tgaatatgat aaatgtatgt gataaatgta
     9901 tgtgatgttg gaaaaagaat aaaagaactt agaatatctt caaatcttac tcaagataag
     9961 attgctgagt atttgtcttt gaatcaaagc atgattgcca aaatggaaaa aggtgaaagg
    10021 aatatcacga atggatttaa gtaataaagc tccaaatctt agaaaaaagt tgggagctga
    10081 tggtgaatcg ccgatagata tttttaaatt ggtacaaaag atagaaaatt tgacgctggt
    10141 attttatgga ctcggaaaga atattagcgg agtctgttat aaaggaactc agttcagtct
    10201 cattgcagtc aattcagaca tgtcattagg aaggtaaaga ttttctttag cacatgaact
    10261 gtatcatctt tattatgatg aggtgaagaa gagttcagtc agtcttatct tgattggtga
    10321 aggagatgaa actgaaagaa aagcggatca gtttgcttct tattttttaa ttttcccatc
    10381 ttcactgtat aggatggttg aggaaatcag agaaaatgcc aatagaactc atcttgaagt
    10441 agaagatatt ataaaattgg gtcagtttta tggtatcagt cataaagcta tgttatatag
    10501 attgaggaat gatggatacc ttgatgcaga agaaattaaa aatatggata ttagtgttat
    10561 agagacagct tcaagattag gctatgatac aagtttatat cgtcctttgt cagaaagtaa
    10621 aaaggaaacg gtattaggat aatatattaa ttcaactgaa caacttttag aaaataacag
    10681 aatttcgcaa gggaagtatg aggaactgtt actagatgct ttcagatatg atattgtata
    10741 tgggctatat gaagaggggg gagttgtcgt ttgactagtc gtgtatttat tgatgcagat
    10801 tgtatttcag tatttttatg ggttggtact gaacatcttt tagaaaagct ctattcgggt
    10861 aaaattgtta ttccacaaga ggtgtacgat gaaatcaata tacctacaat tccccattta
    10921 aaatctagga tagaccagtt ggtaactaag ggttcagctg agattgtgag catagacatt
    10981 ggaactgaag aatacgcatt atatagagat ttaacaagaa atcatgatag taacaagatt
    11041 attggtaagg gagaagcgac ttctattttc ttagcgaaaa agcataatgg gatattagga
    11101 agtaataacc taagagatgt taaaccatat gtagaagaat tttctttaga acatatgaca
    11161 acaggagata tactgattga agcgtttaaa gcgtaattta ttactgaaca agagggcaat
    11221 catatctgga ataatatgct taaaaagaga aggaaaattg gtgcaaattc attttcagac
    11281 tatcttcgtg gaagtattca tcaaaataga caaaaataaa tttggataaa tcgaactcac
    11341 tattcaggag gcatatgagc aattcgaaaa agaaaagtgt caaattgagc ctataggagt
    11401 agaagtgaaa tagtaagtcc tgcatagtgg atgagagaaa agttctcctt gaagttttcc
    11461 tgaactatca gtcgcatgtc aaacgatatg tagggtagtg tgagagggga tagggagtag
    11521 tttttggtta ttttatcaaa aaacttatat tttattatac cgaatgataa aatataataa
    11581 aaatgataga ataaggaaaa aacatgaatg tcaaaaagat aatgtcaatt tttcaatcct
    11641 tttatgttga tgtcagtatt gaggaactga ctttgacttt accaatcagt tttgtaaaaa
    11701 ggtttgagta tactcaaatg acttttcata aggaatcatt tttattgatt aaagaaaaga
    11761 gaagggggag tttgagttca tttgttactc aagctcgcac tatgggtgat aaagccaata
    11821 tggatgttgt tttggtgttt tcgaagttat cagacggtga aaaaaagcaa ttacttcaag
    11881 ctagagttcc gtttgtagac tttaagggaa acctcttctt ccctacattg ggactagtac
    11941 tgaatgcgaa tgatactgaa gtccctaagg aattaacacc tagcgaacaa ttaacgtgga
    12001 ttgccttttt attgccagat ggcgatataa agcagataaa atctgtttct aaccttctat
    12061 atggtggtgc ttatgctttg tcgcattcaa cttttttagc tgaaacggat gaaaatacta
    12121 gctatgtcat atggcagaga aaattcaatc agttatcctt gccactttct cagcatgttt
    12181 taaaatgaaa gatgctagag atatggaaat atcgtccttt tgtatctgag ttttggaatg
    12241 attttaaaaa taatcatgat aaacaatttg tagatccgat ttctctttat ttgaccttaa
    12301 aagatgatga tgacccacgt atagaggaaa agagtgaagc actagaaaat atgatattac
    12361 agtatctggg agaagatgat gccagctaat acgaaagtta tttttcaaga aatgtttgcg
    12421 gattttcaga actattatgt tctgattggg ggaactgcta cctctatcgt attggattcg
    12481 caaggattta aaagtcgcac aacaaaagat tatgatatgg tcatcattga tgaagtaaaa
    12541 aataaggaat tttatactac cttgaatcat tttttagaat tgggagagta tcaaggaagt
    12601 cagaaagatg agaaagcgca gctttttcga tttacaacaa ctaatcctga gtttccttct
    12661 atgattgaac tatttagtat cttaccagaa tatccattaa agaaggacgg tcgagaaatt
    12721 cccttacatt ttgaccaaga tgctagttta tcagccttat tattgaatga agattattat
    12781 aatatattgg tgcatgaaaa agaaaccatt caggggtatt cggtattgag taattgtggt
    12841 ctatactctt cgaaaatctc ttcaaaccac gtcagcttcc atctacaacc tcaaaacagt
    12901 gttttgagca gcctgcggct agcttcctag tttgctcttt gattttcatt gagtattaat
    12961 tatttttaag gctaaagctt ggctggatat gagggaacgc tctgctacag gtgctcaagg
    13021 tttaagtaag tccattaaaa agcatttgaa tgacattacc cgtttgacag cttccttgct
    13081 aggagatgaa aagttatcgg ctataacatc aagtagtgcg gtaaaagcag acatgcaccg
    13141 ctttgtgata gaattagagc ctgtgaagtc aactattctt caaaatgatg acatttcatt
    13201 ggatcaaaat gaaatttttg aaattctgaa aaattttctc gatggttaaa ataattgtag
    13261 cgagatggct atattgaatt cgtttatatc tggaaactag aaaaaacttc aatttcagga
    13321 gaaaatgaag tcaatcttcc cacaatcaaa cgtatagtat caaggttttt caagacctga
    13381 tattatgcgt tttttgcttt tcaaaacttt ttgcccagtc tttgttttta tcctctagtc
    13441 acttgatttg tttcaggtgg ttttttagta tagtaaaatg aaacgagaac aggacaaatt
    13501 gttcaggaca gtcaaatcga tttctaacaa tgttttagaa gcagaggtgt actattctag
    13561 tttcaatcta cggtcaagtc tactggttaa tctatgattg taatactctt ccaaaatctc
    13621 atcaaccacg tcagtcttgc cttgcagtct gtatcttact gaccaagcta gtgatggact
    13681 tagaataggt gatttggagc gtcctattgg ctaggaaatg ctgatcatag tcctttgctg
    13741 aggctagggt gtttcaacat tcaacactca actggttgat ctagttgata ggaagggaat
    13801 tactataaaa tactcaggct tccatcatat tttttgaaac gattgtgtaa tcaaaatgta
    13861 ccaatattgt agtattggta cagaagatgt tgtgaatgga taaatatatc ataactgctg
    13921 tctcaaaaag atttcatatg tctgtgcata tataatagac ttcctgcgaa accaaaatcc
    13981 tagttcatga ttgataatac cagcaatcaa atttattcgt aatccgaagc gtttacgatg
    14041 atttcgatag gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac
    14101 cttgcttctc tccttagata gcgcatggtt acaggcttta tcttcaattg ttagcggctt
    14161 gagtttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata
    14221 accactgtca gccaagattt taccagcttg tctgactttt ttgataagct gtttttaata
    14281 cagctaacat ctcttcaaaa gtggtacgct gaacaccaac aagacgctta aatcgtgcat
    14341 cagttagttg tttacttgct tcataattca tagaactact ataccatatt ttgtttcgca
    14401 ggaagtctaa taagttatag tccagttttt actatacttt gatattcaaa tatgttatac
    14461 tatggttatc aaagtaaatg aaaggagtta cgaatatgac gccagaagaa atgtacctga
    14521 cagagcgatt agacgtacag atagctcatt ttttaaagaa aagcgttcaa catcgtaggc
    14581 gctataaggt attaaaaata acagaaatcg tggcaggttt cctcatagct gtcttttgtg
    14641 ctattcctat gccaggtgat cgctaccgtt tgatttcggt tgccttatcc agtctcggct
    14701 tgctgtgtga ggggattatc aatttgtata atgcaaagga aaattggatt tcttaccaaa
    14761 aaactgcgca actcctggag aaagaaaaat tcctctatca atgccaaacg gaaaaatatg
    14821 caggaaagac caaggctttt gccctatttg tcaagacatg cgaaggtctt atctcagagg
    14881 agattaacca gtgggaaagt atccagtcaa aagaagtggc agctagtgca gatgctccag
    14941 ttaaaaaaga gtaggaggta gaggaaatgt ctcaatccag ctacctgtcg cccttgctct
    15001 ggttaaaaaa agaagccgat aaggaaaaga tgagcgcgac ccagtgccag atatttttct
    15061 tttactatca aatgtttgag ctcttatttg ctagagaaag cgacatgaaa gacttatgtc
    15121 tgggaacgaa aggtttttat ttctcgcagt tagagaaaaa tttgctttct ggagtttccc
    15181 gatttctaaa aaacttggag gggaaagtaa ctctcaaggc taaccaagaa gtatcagctc
    15241 gcaaagccct ttttctagcc ttgacaacta gccaatcaga ttggcaggag ttagctcctg
    15301 tttttgattt ttatcagact atcgggaggc ttgaaaatcc ttctctcttg agttctcagg
    15361 acagacaaca tctgatgtgg atttaccagt cagctttgga gaaggattat attgtcaagg
    15421 ttattggcga caagcatttt gtattgaaga gacaagatgc tactaaattg acagcgcgcc
    15481 aaactcaaac tttggaaatt ctgagtcaat cagaagactt ggtcaatcct gtctatgtta
    15541 cattaggaga aaagggggtg ctcttgcttg attaagagag gagatgttgt agctctttat
    15601 ttgccttttc cgactattag tagcgatttg gctgtgaaga atcatatgta tatctgtatt
    15661 gacaacagca tgactaaaaa caaagagttg gttaaaaatc agaccttcaa accagctctc
    15721 ttgaccagac gtttggtcaa gaactttatg atagaagagc cagatctagc tcgtaatcct
    15781 tttacaagac caaccttgat tgacttagat aaggtattta tgttggataa tacggtcatt
    15841 ccgacttctt atctagccag acggcgacgc aatgtctcag aagaattgta cgaggaaatt
    15901 ttggattact tagtccaacc acggctgatt tcgctgaaca agtctgagtt tatgcaactc
    15961 aatccaggaa cttattagga ggtagaagat ggcaaataaa gcagtaaatg actttatact
    16021 agctatgaat tacgataaaa agaaactctt gacccatcag ggagaaagta ttgaaaatcg
    16081 tttcatcaaa gagggtaatc agctacccga tgagtttgtt gttatcgaaa gaaagaagcg
    16141 gagcttgtcg acaaatacaa gtgatatttc tgtaacagct accaacgaca gtcgcctcta
    16201 tcctggagca cttctcgtag tggatgagac cttgttagag aataatccca ctcttcttgc
    16261 ggtcgatcgt gctccgatga cttatagtat tgatttgcct ggtttggcaa gtagcgatag
    16321 ctttctccaa gtggaagacc ccagcaattc aagtgttcgc ggagcggtaa acgatttgtt
    16381 ggctaagtgg catcaggatt atggtcaggt caataatgtc ccagctagaa tgcagtatga
    16441 aaaaatcacg gctcacagca tggaacaact caaggtcaag tttggttctg actttgaaaa
    16501 gacagggaat tctcttgata ttgattttaa ctctgtccat tcaggcgaaa agcagattca
    16561 gattgttaat tttaagcaga tttattatac agtcagcgta gacgctgtta aaaatccagg
    16621 agatgtgttt caagatactg taacggtaga ggatttaaaa cagagaggaa tttctgcaga
    16681 gcgtcctttg gtctatattt cgagtgttgc ttatgggcgc caagtctatc tcaagttgga
    16741 aaccacgagt aagagtgatg aagtagaggc tgcttttgaa gctttgataa aaggagtcaa
    16801 ggtagctcct cagacagagt ggaagcagat tttagacaat acagaagtga aggcggttat
    16861 tttagggggc gacccaagtt cgggtgcccg agttgtaaca ggcaaggtgg atatggtaga
    16921 ggacttgatt caagaaggta gtcgctttac agcagatcat ccaggcttgc cgatttccta
    16981 tacaacttct tttttacgtg acaatgtagt tgcgaccttt caaaatagta cagactatgt
    17041 tgagactaag gttacagctt acagaaacgg agatttactg ctggatcata gtggtgccta
    17101 tgttgcccaa tattatatta cttggaatga attatcctat gatcatcaag gtaaggaagt
    17161 cttgactcct aaggcttggg acagaaatgg gcaggattta acggctcact ttaccactag
    17221 tattccttta aaagggaatg ttcgtaatct ctctgtcaaa attagagagt gtaccgggct
    17281 tgcctgggaa tggtggcgta cggtttatga aaaaaccgat ttgccactag tgcgtaagcg
    17341 gacgatttct atttggggaa caactctcta tcctcaggta gaagataagg tagaaaatga
    17401 ctaggagagg agaatgcttg cgacaaaaag atgcgatgat ctctctgcgg atatctgaaa
    17461 gtttatctct tgcctagcga tttccattgg agtatgctcg tgatgttaaa atgaatctat
    17521 caaacagaat gtgtaaaaaa gtaaaaaggg tagccaattc cttgatatac aggggattga
    17581 ttatccttta cttgttttag atgattggaa attcaagaac gacacgtatc ggaaatattt
    17641 tgctgtttat atctaatacc catttatgga aaaaatgaaa ttaaatatga acaaatcaat
    17701 tgctagcaat ggtttagaag tgccagtgta ctagtctaac ttctccatct tgggaacacg
    17761 taaattatac tcttcgaaaa tctcttcaaa ccaggtcagc cctatccgca acctcaaaac
    17821 agtgttttga gcaacctgcg gctagctttc tagtttgctc tttgattttt attgagtatt
    17881 agaggtttgc ttagaaactc gtctattaat ttcttagaat acaatagcgc ctataagaac
    17941 tgttggattg caaagtattt actggaacta tgatatgtct ggagtagact gtcaacaaaa
    18001 ggtgcagtat gattgttttt gtcgcttata tctacaaact tcaaacagta atttgagctg
    18061 actttgtcaa acttggctga aactttctat ttgcagataa tggtctagtt tgttttttga
    18121 atgtggatga gtgtctgttg ataaagatag aaaggtaaga ccatcttagc aggtaaagtg
    18181 ctatcctagc ttgatttgct aataaaatcc atttcctcta gtgaaaatca aaaaaacttg
    18241 tgttataata ataaagatta aaatgtgaaa aaaggagatt cctaatggga cgtaaatggg
    18301 ccaatatcgt agccaagaaa acggctaaag atggagctaa ctctaaggta tatgcaaaat
    18361 ttggtgtaga aatctatgta gcagctaaaa aaggtgatcc agatccagaa tcaaactcag
    18421 ctttgaaatt cgttatcgac cgtgctaaac aagcccaagt gccaaaacac attatcgata
    18481 aagcgattga taaagccaaa ggaaacacag acgaaacctt tacagaagga cgttacgaag
    18541 gttttgggcc aaatggctct atgctaattg tggatacttt gacttctaac gtcaaccgta
    18601 cagcagccaa tgtccgtgca gcctttggta aaaacggcgg aaacatgggc gcttcaggtt
    18661 ctgtttctta cctctttgac aacaaaggtg ttattgtatt tggaggtgaa gatgcagacg
    18721 cagtctttga gcaattgctc gaagcggatg tggatgtgga tgacgtagaa gcacaagaag
    18781 gtacaatcac agtttacaca gcgccaactg accttcacaa ggctatcgtt gccctccgtg
    18841 agtctggtat tgaagaattc caagtgactg aattggaaat gattcctcag tcagaagtgg
    18901 aattgtcagg cgaagacctt gaaacctttg aaaaacttta cagcgttctt gaagacgacg
    18961 aagacgtcca aaagatttat acgaacgtag atgggtttta atttaaccta tagaacatga
    19021 tcctaagtga gaaaatcact tgggattttt ttaatcaaga aaatagttct catagaaatt
    19081 taattattct ccagagaact atttttattt agaaggggga gattatgggt aaaccgatgt
    19141 tagtctttaa gcgttttggt catcaaattc acctgatggt gcaaaaggaa gccaaacgtt
    19201 gcggcattga atttatgggt gggccgcaag gttaggttgt gcgttttttg gataatcgcg
    19261 agaaaaacca agatttggtc ttgattaaag atatcgatca ggaactcaat attaccaagt
    19321 ctgttgctag taatctggtt aagcgtatag tgcaaaatgg tttggtggaa ttggaggcga
    19381 gtcctgttga taagcgggct aagtttgttc gtctgacgga caaagcacgt tctcagatgc
    19441 aacaggttaa ggcttttttt gaacgcatag acaagcagtt gatggaagac attgatgaag
    19501 atgaattact gatttttgag aaggttctcg gtcaactaca ggcaaaatat caagggaata
    19561 ggaggagaga ataaagaaat tagccaaaag aattagtaga aaagaatggg ggatgatttt
    19621 actagccatt ctctttactt gcttttcggt ctatctagag ttggaagtgc cgacctatat
    19681 ctcgaaaatt acggatttgc taggtagtca agaaactaat ttagatgagt tgtggcagcc
    19741 ggcaagcatg atgatgggaa tgtcctttct tgccttcttg tccgtagttg cagttggatt
    19801 ttttgcatcc cgagtggcgg cttcttatac tagtaggctg agaagtgata tttttaaccg
    19861 agttttggat tactcgcaga cagagattaa gaaattttca attcctagcc tcttgacgcg
    19921 tactaccaat gacattactc aagttcaaat gttgattact atgggcttgc aagtggtaac
    19981 gcgtggttca attatggcta tctgggctat tgggaagatt ttaggtcatt cagaatactg
    20041 gctctgggcc gtacttgtgg tagtgattgt caacgtcctg atgacgaccg ttttgatgac
    20101 gctagccttt ccaaaacagt ccttgattca ggggttgaca gataaactga acagtatcac
    20161 tcgtgagagt ttaacaggta ttcgtgtcgt tcgtgcctac aatgcagagg attatcaaaa
    20221 tgaaaaattt gcagcagtaa atgatgaatt gacccgtttg aatttgtttg tcaaccgtct
    20281 tatggctatt ttgaatccta tcatgatggg gatttcaagt ggtttgagtg tagcgattta
    20341 ctggattggg gcctatgtga ttaacgacgc tgctccgata gcgcgtctgc ctctctttag
    20401 tgacatgatt attttcatgt cttatgccat gtaggttgtc atgggcttcc ttctcatggg
    20461 agcactcttc atcgttcttc cccgaactat ggtctctgct aagcggatta atcaagtttt
    20521 agatttgcat tcttctatcc aaaaccctgt tcaagtacag ctgactgatg aaaacttcaa
    20581 aggtcaggtc gagtttaagg atgtgacctt ccgctatgcg gcaaattcgg aggcagttat
    20641 tgaacatgtt agctttaaag cagaaactgg tcaaacagtg gcctttattg ggtcaacagg
    20701 ttctggtaaa tcaactctgg tcaatctgat tccacgtttc tacgacgtgt cagcaggaga
    20761 aattctggtg gacggtgtca atgttcaaga ctatgacttc tctgcgacag ctcatgctgg
    20821 tcaaaaggtt gccattgttg ggccgactgg gactggtaag acaaccattg tcaatctttt
    20881 gatgaaattc tatgagattg ataagggaag tattcacatt gatggtgtgg ataccaaggc
    20941 tatgacgcgt tcagaagtgc atgatgcctt ttcaatggtc ttgcaggata cctggctctt
    21001 tgaaggaact attcgagaca atctcatcta taatcaaata gggattagtg atgaacgaat
    21061 gatggaagct agtaaggctg tgggaattca ccactttatt atgaccttgc cagatggcta
    21121 tgataccatc ttggatgaca ccgtgacctt gtctgtagga caaaaacaac tattgactat
    21181 tgctcgtacc cttcttaagg atgcaccgct tttgattttg gatgaggcga cttcttctgt
    21241 tgacacacgg acagaggaat tgatccaaaa agccatggac cgtttgatgg aaggacgcac
    21301 atcctttgtc attgcccacc gcttgtcaac catccgaaat gcagacttga tcttggtcat
    21361 gaaagatgga aatatcatcg agcaaggcaa ctatgaggaa ctgatggcgc aaggtggctt
    21421 ctacgctgac ttgtacaata gtcaatttac agaagatgaa gcagaagaat aaatcaaaag
    21481 aaggcttgac ggccttcttt ttcttattta tactagtaca catagaaaga gagaagtatg
    21541 agtcagaaat tatacaatat gaaatttgct gctgtctact tagccttgat tgcaaaagtt
    21601 gagcgaaagg gtggaaaggc agagtcagtt caccaagtga ccagttggtt gacagggtat
    21661 gaagtgagtg atgttcttgc ttgtctggat agggatgtta cttacggaga tttttttaga
    21721 caagcaccat attatgtccc tgaacgaatt gcaattacag ggaagatttg cggtgtccgt
    21781 attgaggaaa ttgatgatcc tctgatgcag gaaatacgtc gcttggacaa gctagtggat
    21841 tggcttgcca aggggaaaac atctcaacaa gttctagaaa agtatgagaa gcataaatga
    21901 aaaattatca agaatggtat cgaaatatca gctccagact aactagtcgt ccaattcttt
    21961 tattcctatt acgcagtttc aatcgtttga tgacagtcgc catgcccctg gtctatctga
    22021 tcttgctagt caccacttac ctgcaactag gacttggtca gcaagttggg gtttatgtgc
    22081 ttattcctgc atcaggtttt gtggccttgt ccctgtttcg taagaaaatc aatcacccga
    22141 gaccttatga aacttggaat acctgtcccc ttcttgataa ggatagttcg ggacggtcga
    22201 tgcccagtcg ccatgtcttt tcggcaacta tcatctccat ggcctgtctg catgctagtc
    22261 tacctattgg cttagtatgc ttgaactttt cagctttgct ggggttggtg agggttttag
    22321 ggggtgttca ttatcccaag gatgtcttgg ttggctatgc ttgtggtctg gtgtggggat
    22381 tccttttctt cttattctga catgtaagtt aagctagtcc tacaaccact tactgcttca
    22441 aattgaccac ttgctttttt gcccttgtat tcctaactta gctttgatat agtagagtca
    22501 gaaaggagat gtgatgaagt tacgaattga gattgacggc aatttagagg agactgaaat
    22561 tgtcatcaag acccccactt tgacagatga aattgcagac ttgcaacggc tcttgcaaga
    22621 atccaagtct cctaggttga ttttttacaa ggggacgggt gaatattatc tggacttgtc
    22681 ggaaattctc ttctttgaga cagaaggtag caagatttat gcccataccc agaaaaatgc
    22741 ctacgaagtt cggctcaaac tctatgagtt agaggctatc cttcctcgct attttagtcg
    22801 agtatccaag tcaacgatcg ttaatattcg gcaaatctat tcggtggaca agtccttttc
    22861 aggaacgggc accatttcct tttatcaaac ccacaaggag gttcatgtgt cacggcatta
    22921 ccaatccctc ctaaaagaaa atctaagaaa tatgaggtaa gaacatgaaa aagaaagcat
    22981 ttggtattgt gttgcttgta ctagcagctt taatattagt acaaggaaat tttggaatcc
    23041 cttctctagg agggcacatt tggcccttga ttggtattgc tttttttgcc taccaatcag
    23101 ttggagcttt gttgcgtcgc cacttaactt cagcctcttt tacagctcta gtagccttaa
    23161 tgattgctaa ccacttttat ggcattttac cgattccaaa ccagacacta atctgggcag
    23221 gagttctaat cgttctcgga gtaaatatgt tgactcattc taacagaact tggaatggga
    23281 aaaaatggtg gtatgatggt gaaaaaaaca ttcttataga taaggaagtt gcttttggga
    23341 cagggacttt ctacaagcaa gaccaagaat tggtagaaga ccaagtagaa gttggttttg
    23401 gcaatgcaaa aatctactat gacaatgcag agatgttagg tgattttgca actttaaata
    23461 ttgaagtagc ttttggtaat gcaactgtct atgttccgca acactggcgt gtcgatttga
    23521 aagtagaaac atcctttggt gcagccaagg cggacgctcc tgtagcccca accagcaaaa
    23581 ccttgattat ccgtggagat gtggcttttg ggaagttgga aattgtctac gctaaataaa
    23641 aaaatcttca cttcaaccat caaaataggc gtactaagag taggaaattg atgccttgct
    23701 ctgatttcag ttctatggtt gttagacttt aaaaaatgaa atgctgcctt taaaagttgt
    23761 atatttttcg atattttggc ttttacgttt gatgtatcta tgtactacag cgtagatgat
    23821 gtagtgtcga atgcttttaa aaaacgaatg atattggaca gtttttttgc ctttaattgc
    23881 tcaggaacca tgaaagtcag tacttgggtt tatgacaagg gagaatggta ttatgtaagt
    23941 tcttctggtt ccatgattgc gaatgattgg gtcaaagaca atggcaagta gtattatctg
    24001 gcttcatcag gtaagatgct tcgcaatacc tacacacctg atggttacta cgttggcaac
    24061 ttaggtgcct ggcaataaga ataatactct ttgaaaatct cttcaaacca cgtcaacgtc
    24121 gccttatcta caacctcaaa accgtgtttt gagcagcctg cggctagctt tctagtttgc
    24181 tcttagtata agaagtcctt ttccttaaag gaagaggctt tttacttgct tttctgctgc
    24241 ttcctcattt gtcctgaagc cttttttgtg ttaaaatgaa tggtatgaaa gctaaaaaaa
    24301 tgtggatggc aggcttggct ctgctaggta tcggaagcct tgctcttgct acgaaaaaag
    24361 ttgcagatga ccgtaagctc atgaagactc aggaagagtt gacagagatt gtgcgagacc
    24421 atttttccga catgggggaa attgcgaccc tttatgttca agtttacgaa agcagtctgg
    24481 agagcttggt tggtggcgtc atttttgagg atggccgtca ttataccttt gtctatgaaa
    24541 atgaagacct agtctatgag gaggaagtct tatgatacag ccagcaagtt tagaagaatt
    24601 agcatcttta gtggaaaaag cgggcaagaa ggtcttcctt tttgtggcag actggtgtgg
    24661 cgattgtcgt tatatttatc ctgccttacc agagattgaa gagaccaatc cagagttcac
    24721 ctttattcga atggaccgag atcagtatat ggatttggcc aaactctggg atgtttacgg
    24781 aattcctagc cttgttgttc tagaaaagga caaggaaatc ggtcgttttg tcaatcgcga
    24841 ccgtaaaagt aaggagcaaa ttaacgattt tttagcagga ttgaaatagg agaaaaagga
    24901 aacaatgatt tttacgtata acaaagaaca tgtcggtgat gtccttatgg tcatcgtgaa
    24961 aaatagcgga gatgccaaac tgaatgtgga acgcaaaggc aaggtagccc gtgttttcct
    25021 caaagaaaat ggggaaacag tagcttggaa catttttgag gtttcgagct tgtttgaaat
    25081 tgcagagcgc ggtcaagtct ttttatcaga tgagcaagtc gctcgtttga accaagaatt
    25141 acaggcggaa ggttttacag aagaaattgt taatgataag gaacctaagt ttgttgttgg
    25201 tgaaattgtc gagatggtag ctcatccaga cagtgaccac ctcaacatct gccaagttgc
    25261 agtcgcaagt gacaagatag tgcaaatcgt tgcaggagca cctaatgcgc gtgttgggtt
    25321 gaaaaccatt gtggctcttc ctggtgccat gatgccaaaa gggaatttca ttttcccagg
    25381 cgaacttcgt ggtgaaaaga gttttgggat gatgtgtagt cctcgtgaat tgcatttgcc
    25441 aaatgctccg caaaaacgtg gggtgcttga attatcagaa gaccaagttg tcggaacacc
    25501 gttcgaccca gcgaaacact ggactgccta ggaacttgtc agcatctgat agaaggaaat
    25561 aagatggcaa aaaatgtagt gattacggga gcaacctcag gaatcggtga agcgattgcg
    25621 cgtgcttatc tggagcaggg tgatgatgtc gttctaacag gacgacggat agacagatta
    25681 gaaatcctca agtcggagtt tgcagtaagc tttccaaatc aaaccgtctg gacttttcca
    25741 ctagatgtga cggatatggt catggtgaag actgtttgct ctgatattct agaaacgata
    25801 gggaggattg atatcttggt caacaacgcc ggactggctc ttgacttggc tccctatcaa
    25861 gactatgagg agttggatat gttgaccatg ttggatacca atgttaaagg tctgatggcg
    25921 gttactcact gtttcttgcc agcaatgata aaagtcaatc aaggtcatat tatcaatatg
    25981 gggtcaaccg caggaatcta cgcctatgct ggtgccgctg tttactcagc taccaaggca
    26041 gcggttaaga ccttttcgga tggactgcga attgatacca tcgcaacgga tatcaaggtg
    26101 acaaccattc agcctgggat tgtcgaaaca gatttctcaa ctgttcgttt tcatggtgat
    26161 aaagaacgag ctgcgtccgt ttaccaagga atagaagcct tgcaagctca ggatattgca
    26221 gacacagtag tctatgtgac cagtcagcct cgccgtgttc agattacaga tatgaccatt
    26281 atggccaatc aacaggcgac aggtttcatg attcataaaa aataagaaat ttcctcgaaa
    26341 agttacaaat ttctgtaact ttttttgatt tcctacgaat agataagtag gaggaagaaa
    26401 atatgtataa taaagttatc atgattgggc gtttaacgtc tacaccagaa ttgcacaaaa
    26461 ccaacaatga caagtcggta gcgcgagcaa ctatcgctgt caaccgtcgt tacaaagacc
    26521 aaaacggtga acgtgaagct gattttgtta atatggttct atggggcaga ctagcagaaa
    26581 ctttggcaag ctacgcaacc aaaggtagtc tcatttccgt tgatggagaa ttgcgtaccc
    26641 gtcgctttga gaaaaatggt cagatgaatt atgtaaccga agtccttgtg acaggattcc
    26701 aactcttgga aagtcgtgcc caacgtgcta tgcgtgaaaa taatgcaggc caagatttgg
    26761 cagatttggt cttggaagag gaagaattgc cattttaata ctcttcgaaa atctcttcaa
    26821 accacgttag ctttatccac aacatcaaag caatgctttg agcagcttgc ggctagcttc
    26881 ctagtttgct ctttgatttt cattgagtat aaacattaaa aagtctgagt tggtctcagg
    26941 ctttttatct tgagaaagtc agactttttt cttgattatt tctgactaag tgatacaata
    27001 gaactatgaa ttagcactca ggtataaaga gtgctaataa tatctatctc attatggagg
    27061 aaatcagatg ttgaaaccat taggggaccg tgtggtctta aaaatagaag aaaaagaaca
    27121 aaccgttggg ggctttgttc tcgcaggttc agcccaagaa aaaaccaaaa cagcccaagt
    27181 tgtggctact ggacaaggtg ttcgtacctt gaacggtgac ttggttgctc caagtgttaa
    27241 aactggagac cgtgtcttag ttgaagccca cgcaggtctt gatgtcaaag atggcgatga
    27301 aaagtacatc atcgtaggcg aagctaacat cttggcaatc attgaagaat agaaggagaa
    27361 agtaagtatg tcaaaagaaa ttaaattttc atcagatgcc cgttcagcta tggtccgtgg
    27421 tgtcgatatc cttgcagaca ctgttaaagt aaccttggga ccaaaaggtc gcaatgtcgt
    27481 tcttgaaaaa tcatttggct caccattgat taccaatgac ggtgtgacta ttgccaaaga
    27541 aattgaatta gaagaccatt ttgaaaatat gggtgccaaa ttggtatcag aagtggcttc
    27601 aaaaaccaat gatatcgcag gtgatggaac tacaactgca actgttttga cccaagcaat
    27661 cgtccgtgaa ggaatcaaaa acgtcacagc aggtgcaaat ccaatcggta ttcgtcgtgg
    27721 gattgaaaca gcagttgccg cagcagttga agctttgaaa aacaacgcca tccctgttgc
    27781 caataaagaa gctatcgctc aagttgcagc cgtatcttct cgttctgaaa aagttggtga
    27841 gtacatctct gaagcaatgg aaaaagttgg caaagacggt gtcatcacca tcgaagagtc
    27901 acgtggtatg gaaacagagc ttgaagtcgt agaaggaatg cagtttgacc gtggttacct
    27961 ttcacagtac atggtgactg atagcgaaaa aatggtggct gaccttgaaa atccgtacat
    28021 tttgattaca gacaagaaaa tttccaatat ccaagaaatc ttgccacttt tggaaagcat
    28081 tctccaaagc aatcgtccac tcttgattat tgcggatgat gtggatggcg aggctcttcc
    28141 aactcttgtt ttgaacaaga ttcgtggaac cttcaacgta gtagcagtca aggcacctgg
    28201 ttttggtgac cgtcgcaaag ccatgcttga agatatcgcc atcttaacag gcggaacagt
    28261 tatcacagaa gaccttggtc ttgagttgaa agatgcgaca attgaagctc ttggtcaagc
    28321 agcgagagtg accgtggaca aagatagcac ggttattgta gaaggtgcag gaaatcctga
    28381 agcgatttct caccgtgttg cggttatcaa gtctcaaatc gaaactacaa cttctgaatt
    28441 tgaccgtgaa aaattgcaag aacgcttggc caaattgtca ggtggtgtag cggttattaa
    28501 ggtcggagcc gcaactgaaa ctgagttgaa agaaatgaaa ctccgcattg aagatgccct
    28561 caacgctact cgtgcagctg ttgaagaagg tattgttgca ggtggtggaa cagctcttgc
    28621 caatgtgatt ccagctgttg ctaccttgga attgacagga gatgaagcaa caggacgtaa
    28681 tattgttctc cgtgctttgg aagaacccgt tcgtcaaatt gctcacaatg caggatttga
    28741 aggatctatc gttatcgatc gtttgaaaaa tgctgagctt ggtataggat tcaacgcagc
    28801 aactggcgag tgggttaaca tgattgatca aggtatcatt gatccagtta aagtgagtcg
    28861 ttcagcccta caaaatgcag catctgtagc cagcttgatt ttgacaacag aagcagtcgt
    28921 agccaataaa ccagaaccag tagccccagc tccagcaatg gatccaagta tgatgggcgg
    28981 gatgatgtaa gctttctata gaaaacaact tataaaaaac acaaaaggag ggaatgacta
    29041 acccttcttt ttataatatt cacttctaaa ttgatttgag ctcttctaac ttatatgata
    29101 aaataagact agaaaaagga gaagaacatg atcgatgtag aagaaattct gtgcaagatg
    29161 ccccccaatc agaagattaa ttatgaccgt gtcatgcaga aaatggtaca agcatgggag
    29221 aaaaatgagc agcggccaac cattctcgtg catgtttgct gtgccccttg tagtacctat
    29281 acactagaat atttgaccaa gtatgcagat gtgaccatct attttgccaa ttctaatatc
    29341 catcccaaag tagaatacca taagcgggtc tatgtcatca agaaatttgt tagtgatttt
    29401 aatgatcgga caggaaatac ggttcagtac ctagaagctc cctacgaacc caattaatac
    29461 cgaaaactag ttaggggact agaggaggag cccgaaggtg gcgaccgttg caaggtttgt
    29521 tttgactacc gactggataa aacagcgcaa gtggctatgg acttgggctt tgactacttt
    29581 ggttcagcct tgaccatcag tcctcataag aattctcaaa ccatcaatag catcggaatc
    29641 gatgtgcaaa aaatttacac gacccactat cttcccaacg atttcaagaa aaatcaaggc
    29701 tacaaacgtt cagtagagat gtgtgaggag tatgatatct atcgtcaatg ttattgtggc
    29761 tgcgtctatg cagcccaagc ccagaatatt gacctggttc aagttaagaa ggacgccaca
    29821 gcatgcttgt tggataagga tgttgagaaa gactattctc atatcaaatt tatagtagat
    29881 tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat ttgactgtcc
    29941 ttatttcatt ttactatact gttacgaaat tagatatata aatgaaaact tgcctcaagg
    30001 taggtttttt gctagtagaa aagcgataga cagaaattgt tggactctta aaaaaatgaa
    30061 gttttgctca aaagagcttc ttaaattaaa acgagcaatt atcagttcaa atctgtttca
    30121 aaagaagaac ggataaatta atcgatgctt tgtttttgag ttaggaagtt aagcatgcca
    30181 aactgagtcg taggaataaa tttctttata gaaatgtgtt gtaactctgc tataatggat
    30241 ttattccttt ttgtgtttac acaatttatt ttatactacc aaaaaaacaa ggtcaggatt
    30301 ttgttcctga cctttgacaa ctttaccgat tctttagttc tacatagcgc ttgtaccaaa
    30361 tgtttacata ggcttctgag aaaggaccac gtccattgtt aatccaatca acaagaattt
    30421 tgacatgttc ttttaaaata tagtccaagt catcagaata attcattttg cgtttgtgac
    30481 gctcgtactc ttcaacgtcc aagagacgtt tttccccatc tgtaaaaatt ttaacatcca
    30541 aatcgtaatc aatatacttc agtgcttctt catccagata gtaggggcta gccatattgc
    30601 aatagtaaga agttccatta tcacgaatca tggcaatgat attaaaccaa tatttcttgt
    30661 gaaagtaaac aatagccggt tctcgagtga cccaacgacg accatcactt tcggtaacaa
    30721 gtgtatgatc gttgacacca ataatggcgt tttctgttgt ttttagtacc atggtgtccc
    30781 gccaagttcg gtggagactc ccatcatgct tataactttg aattgtaata aagtcgcctt
    30841 cttttggaag cttcataact aaccaacttt ctacaattta taagtttatc atttactatt
    30901 gtaccataaa attacctaaa atctgtgaat ttcacttgga aatattaaag atattctcta
    30961 agagcgcttg ctatatccga aaaatcgtag ccctttcgtg ctaaaacttg agttaaacgc
    31021 tgcttcagtt cgtatccttc atactttcga gcatacttag tatattgctt atcaagttcc
    31081 ttgaagatga gttcttgagt cgtttcttgc tcaacttggc tatctaagtc gtcaaaggca
    31141 attttagcat cagaataaga gaagcccttg ttagtcaagt tctggataat tttatcttgc
    31201 agggcacgag ctggaagttt tccctcatat tttttcaata gtttattagc tacacgttga
    31261 gcaacttcag aaaaatcaaa ttctttcaag ttctcttcta tagtagattt tgaaatccct
    31321 ttttgagcta gtttctgagt cagcacataa ggacccttgt ctcctgaaag ttgattggta
    31381 ttgatgatag cataagcgta ctgaccatca ttaatccact tatcttcttt aagattagca
    31441 ataacttgag aaacgatgtt ttcatcaata tcgtattttt tcagatattc tctgacttct
    31501 ttttcagtgc gtgctttaaa ggataagtgg tagagggcca gattcttacc ataagaaaat
    31561 tgagcaaagt cttgaatctc tttcaattcc tcttcgctta tcaccttatc tctcgataac
    31621 ataaaacgaa caattgtatc ttcggtgata tagcatttgt cgccattatc aagctccatc
    31681 agatagagtc tttttttctt ttcaagtttt gtgattttca tagctctatt ataactcaaa
    31741 atgtgataag ataggggtat gaatctgaaa gtgaaacaaa aaataccatt aaaaatcaaa
    31801 cgcatgggaa ttaatggtga gggaatcggc ttttaccaaa aaacattagt ctttgtacct
    31861 ggagctctca aaggcgaaga tatctattgt cagattactt ctattagacg caactttgtt
    31921 gaagcaaaat tactgaaggt caacaagaag tctaaatttc gaattgtgcc atcttgtact
    31981 atttataatg aatgcggagg ctgccaaatc atgcacctgc attatgataa gcagctggag
    32041 ttcaagacgg acttacttca tcaagcgctg aaaaaatttg ctcctgcagg atatgaaaat
    32101 tatgaaattc gtccaactat tggaatgcag gaaccaaaat attacagagc taagttacaa
    32161 tttcagactc gaaaatttaa aaatcaggtc aaggcgggct tatatgcaca aaactctcac
    32221 tatttagtag agttgaaaga ctgcctggta caagataagg aaacccaagt gattgctaat
    32281 cgcttagcag aattacttac ttatcaccag attccaatca cggatgagag aaaagttcta
    32341 ggtgtccgta ctattatggt ccgacgcgcg agaaagaccg gacaggttca gattattatt
    32401 gttacaaacc gccagcttaa tttaacccaa ctggtaaaag agttggttaa aggttttcca
    32461 gaagttgtga cagtagctgt taatacaaat acagctaaaa ccagtgagat atatggtgaa
    32521 aagacagaga ttatctgggg acaagagagt attcaagaag gtgtactcga ttatgaattt
    32581 tcactatccc ctcgagcttt ctatcaacta aatcctgaac aaacagaagt cctttatagc
    32641 gaggtagtaa aagcgctgga tgttagtaaa gaagaccatt tgattgacgc ttattgtgga
    32701 gttggaacaa ttggttttgc ctttgcaaag aaagtaaaaa cactcagagg tatggatatt
    32761 attccagaag ctattgaaga tgccaagcga aatgctaaaa gaatgggatt tgacaatact
    32821 cattatgaag ctggaacggc agaagagatt attcctcgtt ggtacaagga aggctaccga
    32881 gcagatgctt tgattgttga cccaccacgt acaggtctgg atgataagtt attagatact
    32941 attcttactt atgtaccaga aaaaatggtt tatatttctt gtaatgtttc gaccttggct
    33001 cgtgatttgg tacgcttagt agaagtctat gatcttcatt atatccagtc ggtcgatatg
    33061 ttcccacata cagctcgaac tgaagctgtt gtaaaattaa taaaaaaagt ttaaaaaagg
//
LOCUS       DAVHSL010000023        32549 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000023 DAVHSL010000000
VERSION     DAVHSL010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.023"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(168..1265)
                     /locus_tag="VVR39_001073"
     CDS             complement(168..1265)
                     /locus_tag="VVR39_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU6030576.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(1275..2021)
                     /locus_tag="VVR39_001074"
     CDS             complement(1275..2021)
                     /locus_tag="VVR39_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6030577.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRLSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(2124..2477)
                     /gene="rsfS"
                     /locus_tag="VVR39_001075"
     CDS             complement(2124..2477)
                     /gene="rsfS"
                     /locus_tag="VVR39_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU6030578.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(2490..2990)
                     /locus_tag="VVR39_001076"
     CDS             complement(2490..2990)
                     /locus_tag="VVR39_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6030579.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            complement(2991..3584)
                     /gene="yqeK"
                     /locus_tag="VVR39_001077"
     CDS             complement(2991..3584)
                     /gene="yqeK"
                     /locus_tag="VVR39_001077"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU6030580.1"
                     /translation="MSYQDYINCSREVLLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(3584..4213)
                     /locus_tag="VVR39_001078"
     CDS             complement(3584..4213)
                     /locus_tag="VVR39_001078"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU6030581.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(4265..4576)
                     /gene="yhbY"
                     /locus_tag="VVR39_001079"
     CDS             complement(4265..4576)
                     /gene="yhbY"
                     /locus_tag="VVR39_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU6030582.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(4790..5896)
                     /gene="yqeH"
                     /locus_tag="VVR39_001080"
     CDS             complement(4790..5896)
                     /gene="yqeH"
                     /locus_tag="VVR39_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU6030583.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(5899..6489)
                     /locus_tag="VVR39_001081"
     CDS             complement(5899..6489)
                     /locus_tag="VVR39_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU6030584.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(6441..7349)
                     /locus_tag="VVR39_001082"
     CDS             complement(6441..7349)
                     /locus_tag="VVR39_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6030585.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(7406..7966)
                     /locus_tag="VVR39_001083"
     CDS             complement(7406..7966)
                     /locus_tag="VVR39_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEU6030586.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            8105..9323
                     /gene="sstT"
                     /locus_tag="VVR39_001084"
                     /pseudo
     CDS             8105..9323
                     /gene="sstT"
                     /locus_tag="VVR39_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            9391..10344
                     /locus_tag="VVR39_001085"
     CDS             9391..10344
                     /locus_tag="VVR39_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6030587.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(10670..10750)
                     /locus_tag="VVR39_001086"
                     /pseudo
     CDS             complement(10670..10750)
                     /locus_tag="VVR39_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10805..11029)
                     /locus_tag="VVR39_001087"
     CDS             complement(10805..11029)
                     /locus_tag="VVR39_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEU6030588.1"
                     /translation="MIDILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(11034..11213)
                     /gene="asp4"
                     /locus_tag="VVR39_001088"
     CDS             complement(11034..11213)
                     /gene="asp4"
                     /locus_tag="VVR39_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEU6030589.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(11215..12552)
                     /gene="gtfB"
                     /locus_tag="VVR39_001089"
     CDS             complement(11215..12552)
                     /gene="gtfB"
                     /locus_tag="VVR39_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEU6030590.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYDVLGQAIMTSYRDVDQKEVILENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHYPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINYSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGRQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(12545..14056)
                     /gene="gtfA"
                     /locus_tag="VVR39_001090"
                     /pseudo
     CDS             complement(12545..14056)
                     /gene="gtfA"
                     /locus_tag="VVR39_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
     gene            complement(14068..16440)
                     /gene="secA2"
                     /locus_tag="VVR39_001091"
     CDS             complement(14068..16440)
                     /gene="secA2"
                     /locus_tag="VVR39_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEU6030591.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGDGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDMIYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(16433..16873)
                     /gene="asp3"
                     /locus_tag="VVR39_001092"
     CDS             complement(16433..16873)
                     /gene="asp3"
                     /locus_tag="VVR39_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEU6030592.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(16870..18405)
                     /gene="asp2"
                     /locus_tag="VVR39_001093"
     CDS             complement(16870..18405)
                     /gene="asp2"
                     /locus_tag="VVR39_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEU6030593.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSEALREIIEK
                     EDINRFHAVLIEDGQYAKDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(18389..19969)
                     /gene="asp1"
                     /locus_tag="VVR39_001094"
     CDS             complement(18389..19969)
                     /gene="asp1"
                     /locus_tag="VVR39_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEU6030594.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNSQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(19979..21196)
                     /gene="secY2"
                     /locus_tag="VVR39_001095"
     CDS             complement(19979..21196)
                     /gene="secY2"
                     /locus_tag="VVR39_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEU6030595.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRR
                     RMYLTLLIAVIQSLAVSLSLPVQSSYSVILVALMNTLLLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSIVLNIPQDVIETFKLVYIPTGIVVLLVFMTIIFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            complement(21253..22158)
                     /locus_tag="VVR39_001096"
     CDS             complement(21253..22158)
                     /locus_tag="VVR39_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6030596.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDSSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCILAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            complement(22158..23354)
                     /locus_tag="VVR39_001097"
     CDS             complement(22158..23354)
                     /locus_tag="VVR39_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU6030597.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNTGMLLMDVVKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(23363..24583)
                     /locus_tag="VVR39_001098"
     CDS             complement(23363..24583)
                     /locus_tag="VVR39_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEU6030598.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQYTMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKTMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(24614..27058)
                     /locus_tag="VVR39_001099"
     CDS             complement(24614..27058)
                     /locus_tag="VVR39_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEU6030599.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDTVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNTGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLIANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKQLAVYNNVRLHPQIVPPVLD
                     KLERSVDLYLDINYSHVVGTILEDMKILEKPIPSFDTTEHGNTGQLVFKKDEVSVMVQ
                     AIKDYRRDGRFLSCYEGSDFHCLTFTNSQELQKIDYLVKNFPMVTFHIAAWTVMGPML
                     QELAKKYKNVKLYPEVKSDQFEELKSQMDVYLDINLHNSTSEVVKEISSLNKPMLAFY
                     TSQNGNHGQHLYSSEHPERLLQAFHALIKGETLGEPEKPIKVIGIDQTLDYVIKNKSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAENRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(27068..28078)
                     /locus_tag="VVR39_001100"
     CDS             complement(27068..28078)
                     /locus_tag="VVR39_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6030600.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAEFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(28107..28697)
                     /locus_tag="VVR39_001101"
     CDS             complement(28107..28697)
                     /locus_tag="VVR39_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEU6030601.1"
                     /translation="MEHDALDRLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDD
                     SLEVIEGKAIMDREGVEEVRNGNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVL
                     LRASRIVYLNRCVYWYRVGLSDTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHI
                     LIYKNRLQRVIAKLEEQNMQFTEIYRRMMEKLSLLP"
     gene            complement(28705..28986)
                     /locus_tag="VVR39_001102"
     CDS             complement(28705..28986)
                     /locus_tag="VVR39_001102"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6030602.1"
                     /translation="MGNELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGGGVHYFCRL"
     gene            complement(29026..29904)
                     /locus_tag="VVR39_001103"
     CDS             complement(29026..29904)
                     /locus_tag="VVR39_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEU6030603.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLSNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVACRNFENFHVSSGKLILNDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLCVKRRD"
     gene            complement(29901..31279)
                     /locus_tag="VVR39_001104"
                     /pseudo
     CDS             complement(29901..31279)
                     /locus_tag="VVR39_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854349.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
     gene            complement(31347..>32549)
                     /locus_tag="VVR39_001105"
     CDS             complement(31347..>32549)
                     /locus_tag="VVR39_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6030604.1"
                     /translation="TSASASASTSASASASTSASASASTSASVSASTSASASASTSAS
                     ESASTSASASASTSASESASTSASASASTSASASASTSASESASTSASASASTSASAS
                     ASTSASASASTSASASASTSASASASTSASALASTSASASASTSASTSASTSASASAS
                     TSASASASTSASASASTSASASASTSASESASTSASVSASTSASASASTSASESASTS
                     ASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASAS
                     ASTSASASASESASTSASASTSAGKSRQQLPNTGTEASKSSVLLGALAAVTGLGLFAK
                     RRKRDDEE"
BASE COUNT         9779 a         7208 c         5587 g         9975 t
ORIGIN      
        1 aataacaagc ataaagcgga ttcaaagata aagattaagg ttcatatact aattttcttt
       61 attgactttt tgtcttctgt attagggagt ttatcatttt ccaaaaactt tatcttcaat
      121 ttgttatcta aaatttctac aataaaaaag cctacctttc agtagactta gtttgtttct
      181 attctaatcg gcactctgcc aaaattctgt tctgctatac ttggatttcc caattggtaa
      241 atctggtctg ccttttgagt catgacatcc caaggttcct tgccaattct gctgactaga
      301 ctgacctgcc ctttcagata tttaagatgt tgcctgcctt tttcggtaaa gccaaggaca
      361 tgaatggctt ctggcaagac attttcccta gcctgcacca aaatataggt caataggcgt
      421 ctgacacgcg ccttggtgta acgtttagta gtcactaact cgaccaattc ttccacagac
      481 tgggctgttt taatagcttc tttaatgcgc acagccattt cttgattgac ctgatagatg
      541 gtggttaggt cgggatttga caagatttga tagcggagca agggaaaata gtcttcccag
      601 atcaccttac tggcctgctc aaatagggca acagaaggca taaaacgttc taagaaatct
      661 tggtccttct gatgttgacg gagggctgtc gccgaggcaa agtccacatc tttattcaca
      721 gaatggtaac ctgccccctg acgctgaatc ggatgcagct tgatatttcg tcctgcaacc
      781 gcctttgcat aggccagagc aagaacatga ttgggggtat tacctgaaaa atcaagacca
      841 gcaaattcct tccacatagc ttgggttttc tggggatagg aaagggaatc aggcagattt
      901 tccacaaatt tctccatctc agcacctttc tctgtgtata agtcagcgat tttctgataa
      961 tctcgaactt cctctgtccc aaaaactaga ctatcaatgc ccaagcgatc caagatatcc
     1021 acagctcctt gaccaaagaa atcagctgcc tgaacactga ctaaaaaggg caattccact
     1081 accaagtctg cgccattttc cagcgccatc tgggcccttg tccacttatc cacaatagca
     1141 ggctctccac gctgcatgaa attccctgac atggcaacaa ttttcagtcc ctctgcctga
     1201 tccagcaggt atttatggcc attatgaaaa ggattgaact ccgcgataat acctgtgatg
     1261 gtcatgctaa tctcctactt ctgcgccaca aaaaaccaac gggtgctagt ttctgttggc
     1321 tccttatcct caaagtctgc atagagtttg aaggacttga atccagcctg ttccagtaag
     1381 atatcatagg tcaagatctc ataggtcctc tcctcatgta cttcatcgtg gcgactaaag
     1441 gaaccgtcag cctccttgat aaagaaagtc agctcatgca cgatggagtg aggagcttcg
     1501 tcctcatatg tatcccaaag catggcaaaa tcttccgcat tttcatggta ggaatagcca
     1561 gggaatactt catctgtctg gtaggtcgag tgcacgtcaa agatgaaaac tccctcttca
     1621 ttcagcgcat tgtacacgtc cttaaagacg tcccctactt ccacctcatc ctgcatatag
     1681 cagatagagt ccgaataaca cgtgacaaaa tcgtatttcc ctgccttgga caaattcagc
     1741 atattacctt ctataaaagc aatcttttgc ttggctgaag ttgctctctt ctccgcaatc
     1801 ttcaacatat ccgcactcaa gtcaagtcca gtcacatcaa aaccagcctg agataagcgc
     1861 actgattgaa ttcctgtccc acaagccagt tccaagagtt tctttttctc cttggtctta
     1921 ggcaaatgac gcagagaaaa atttgtccat ttgtcgtata aactatcgtc catgaccgca
     1981 tcatagaccg ccgcaaaggt ttcataagtc gccataatca tgatactaag agctccatgg
     2041 taaacaccac tagcccttta cctttctatc aatttttcta aaataagcaa agaaacccag
     2101 ttgactacaa ctgagttcat cttctaagca agagcttctg aaatatctac tgaattcgcc
     2161 tcatgccata gcttctctag gttataatgg gcacgcattt cttctgaaaa gatatgcacg
     2221 acaacagcac cgaggtccag taagacccag cctccagctg catcgccttc gacatggcta
     2281 cctttaaagc ccgcttgagc tactttttca cggatattag ctgcgatagc gtccaactga
     2341 cggctattca ttgagctagt gatgacaaag tagtccgtca cactagtcaa atcttgtaca
     2401 tcaagtgcga ggatatcctc cgcacgtttc tcatcagccg ctttcacgac tagttctagt
     2461 aattcttttt cgttcattta atcctctttt tagaaaatat gtttgtaatc taggacatct
     2521 gcaaagtgct cctcccaaat gtcctcataa aattcattaa tcgtttctgc tggaatgtca
     2581 tccccatcaa aggttgtgac agcaccttct ggaacaataa gctgatagcc atattcaaag
     2641 gcaaccttga cagaggtatc cacacaatat tctgtctgca taccacataa aactaatttt
     2701 tcaatcccct gcttatccaa gtattctttt aagccagttt ctttgaaaat actgttatac
     2761 ttcttctgaa agaccttttc agcaggtttt cgatttaaaa gcgcagataa ctgccaatct
     2821 tctgatgttt gagcttcaga gttctcaata tgttgaacat agataatttc aatattcttg
     2881 cttctagcct ggttttgtaa ataagaaatt tttcccaata gactttttgt ctggaatcca
     2941 gtttctacta aaacattctg aacatcaatg attataaaag ccgtcttcat ttagttctct
     3001 ttcaaatagt gcacaaaggc gttataggtt tcaagggttt ggggatagat ggggaatccc
     3061 tgatgagcta gatactccac ggtacgagct gtttcgtagg ccaccgcctt attgagcgat
     3121 agacttgcaa tctcacgcgc cacatctact ccaggaaagg ctcgattgtg ctcgatatag
     3181 tctgcgacgt agatgacctt atctaggtct gtcatttgac cagcaccgac tgtatggact
     3241 tcaatggctc gcagaatttc agaatcatgc aaatccaaat cttcctgaat tttgtaaatt
     3301 ccgaccatac catgccagac attattaccc cagtttttga ggtcgaaatc tagctgataa
     3361 cggtcaatca aggctagaaa ttcctgatct gacaactttt tagcatagtc atgaagaaga
     3421 cctgctagac ttgctttctc aacatctaca ccaaagcgct gagctaattc catagcggca
     3481 cgctccacac ctagacaatg ggttagacgt ttctcaggta gaagctctgc cattttttcc
     3541 aacaaaacct cacgggagca gttgatatag tcttgatagg acatcagtag agcccctcct
     3601 tctcgatgta gtctagcact ggctgaggta ggagaaagtt gggtttccga ccttgggcaa
     3661 tgaagtcccg caccatgctg gacgagatat ccatgagcgg tacgtccacc cagataactg
     3721 gataggaagt ccctgccttg tagcgtggac gctgaacccc cacaaactga accatgtcaa
     3781 ccagttcatc aattcggtac cacttaggca gatagtcaac catgtcggcg ccgatgataa
     3841 agtaataatc cgtatctgga ttcttctctg tcaaaatctt catggtatcg taggtgtagg
     3901 aaataccctt gcgctccaac tcaatggttt caatgactag gccgtcaatc ccctcaattg
     3961 ccaactcaag catcttgaga cgatggtgtt cagggatggt ttccttttta tcaacgtgag
     4021 gaggttggta ttcaggcatg agaagaactt gatccagtcc caactgttgc cgtacttgat
     4081 ccgcaacaat gagatgggca ttgtgaacag ggttaaaatt cccccctaaa atcccaactt
     4141 gtttgcgttt tttctccttg atttctggct ccaactctac cttggtaaag ggagtcaata
     4201 gttcgattgt cataggctag tcccctttat ttctctataa aaacagttat ttggagtttc
     4261 ggtcttagat ttctttgact ttcttagaaa tcttgcgatt ttctttcttg ctagattgtt
     4321 taaacaaaat caagatgcgt cctatttttt ggactgtatc cacaccgatt tcttcttcca
     4381 aaatttcagc tacttcgtgg atgttttcat ctgtgttttg taagagagta accttgatta
     4441 attcacgcgc atcaagagct tgacggacgc tggttttgat ttggtcgttg agtccatttt
     4501 tcccgatttg gatgataggt ttgagggtgt gtgcctggct gttgaggaag gcacgttgtt
     4561 ttgatgttaa tgacataatt ttcttccttg ttttttgata gttattttag gtggtgaggg
     4621 acggtcggaa ctaattttcc aaagatttca tctttgaaaa atggatttcc tgacctcaca
     4681 attgagcctt ggtctcaatt gtgccccttg ccaatctaca gattggcaat cacaccacgg
     4741 caataactat cgctatatga gctcactttg ttcgctcagc gattttgttt taaataattg
     4801 cttttcgtgt gacgacggcg acgccttctg gtgcccagac ggcgactttt gctatgcctg
     4861 ttacacgaat ccagcctagg cctgagatga ctaggtctgt cttatcttta atggtaaaga
     4921 catgctggac tagccttggg aaatcttctt tttccttgct atttggtggt gtcagaagag
     4981 ttcccaggtg cttatcgtag aaagcactag ctccttcaag cttgctacga tggagtttga
     5041 gttcattatc aaagaaagca gtaaatcctt gcttttctcc tgctataaag tcaaagcgtc
     5101 ccaaaccacc taaaaatagg gtttgctcag gattaagctg ataggtctta ggcttgattt
     5161 cctttttagg actgacatac ttgaggtttt tggccgtcaa gtagtgagcc atctggtggc
     5221 ggtggataat tcccggcgta tcgtaaatat aagatccgtc gtcaagcgga atctctattt
     5281 tgtccaaggt tgtccctgga aagcgtgaag tagtgatgac attctgatca cccgtgattt
     5341 cttggataat agcattgatt agagttgatt ttccaacgtt ggtcacaccg accacataga
     5401 catcgcggcc cttacggtag tgttcaatct tatcaatgac ttccttaatg gcatgtttat
     5461 tttgtgctga agttaggacc acatcgactg gacgaagacc ttcttcatgg gcacgtttca
     5521 tgagccactg gctaatctta ccagacttaa ctgacttagg aaggatatct tttttatttc
     5581 ctaccaagag gacatcattg cccgagacga aacgtggtaa acctgggatg acagatccat
     5641 taaaatcaaa gatatcaatg acattgacca ctaaagcatc actgtctccc acctcgtgca
     5701 agagcttgag gaaatcatcg ttcgtcaact ggacatctgt gatttcattg tagtggcgga
     5761 gacggaaaca gcgttggcaa tagacttcgc cagtctccaa acctttttca agtgccgact
     5821 ggggggtaaa accaagacca gccttatctg tcgtctgaat ggttgctcca caaccaatac
     5881 agagaatttc ttccatagtt aaattccttt tttatatgta atcggtccgt acttttcagt
     5941 gatttttctc ataacacgac gctcacgagt tcggttaatc tgcgttttga ttgagtcatg
     6001 ttggaccaag ggtttgacta aaattgaccg aatccctgca cggtgggctg ctcgtatatc
     6061 tgtcatgagc tggtcaccaa ccatgaccac ttcctttttg tcatagtgga attccttcat
     6121 agcacggtca ataccaaatg tgaagggctt caaggcccag taaacgtaat caataccaaa
     6181 tttctcaact gctcgttgaa cgcgtttttt ggtgttattt gacactacga taatgccaat
     6241 acccgcgtcc cgaaggtcat gtagccattg cttcatctct ggcgttccat cagggttgtt
     6301 ccaagcaatg agggtattat ccaaatcgac caaaacagcc ttgattccct gcgcctgcag
     6361 gcttgggact gtcagatcat agactgcttc cacagcaaaa tctggtatat aattttcaat
     6421 cgccattctg gctccttttc ttaacttttt ttcgcaattt tccttagtaa caaggataaa
     6481 acaatccaca aacctgcact agccaaacta atatagagcc aagcatgggg ctcatctgtt
     6541 aaaggtaagg gaacattcat tccgaaaaag cctgtcacga ctgccaaaac agctagcaag
     6601 actgaaataa tagtcaaggt tgtcaaattg tcattcaaat tattgtttag aatattgttg
     6661 taagaggctg aaagctgctg taaaatctga gagattaggt ctgtcatgga taccagctga
     6721 tgagcctcaa tcatggcatc atcaaactgt tctctctcaa tctcatcaaa actacgatac
     6781 aaggcatgac cttgaatatg ctctaacaaa atccgatttt gtttggcagc tgccgtcaga
     6841 taaaccatac cagtctccaa atcagacagg gcaaagaggt ttttcttggt agttcgctgg
     6901 cgcaagaggt cattgacctc atccctactc ttgtccatct gctcaatgac aggatagtag
     6961 gcattgctga taatttccag actggcaaag agaaacttat aaatcgaaag cgtgtcatgg
     7021 ttttccagat aacgagtcat ctgttcaatg acataggcgt tcttggtatt actaatggta
     7081 atcaggcgac gatgctcgac aataaaggtc atgggaaaag tctcatagta ggccttgtcc
     7141 ttttttacgt ctaggacatt atagataaag gtaaccgtcc cactttcacg gtggtagtcc
     7201 atgtgggcgc gctcgtttct atccagtgcg tattcaatgg tttccttgtc caaaccgtaa
     7261 atttcagaaa ggtcttctag tttattcaac tttcctaggt ctaggtctat ccaggtacaa
     7321 ccattgccca actgcttttc taaaaccatc ttttctcctt attaaactcc ctctattgta
     7381 ccacaaatta cttaaaataa caggtctagt ctgtgcgtga gaaattgcta acaactgtga
     7441 tatttcggtt agggacaaag tgaaggactt gctcctcgct acgaagctgt gtcgtacgaa
     7501 ttcccacact gacaacctta cccgatacag taatcggtcc atttgtcaga acgacctcat
     7561 ctcccacatc cagttgacgt tcaaagagga tgaaaaagcc attgatgaca tcagatagaa
     7621 agccttgggc tcccatacca atcgctaccc cagcaatacc agctccagcc agcaaactag
     7681 aaactggcaa acctaaaatc gacaaaatgc agtagagtaa aaagaaatat agcgtataat
     7741 taaacacatt ttctagtaaa cgtgagatgg ttttttggcg tccaacatca tgacgagaca
     7801 tttttagaga aggtttgaca attctctgca ccatggtatg aagcattttt ttagcaatat
     7861 aaaatacaat caaaagcagt aaaagagaaa tgaccttggt tagaatattc tcgataatgg
     7921 ttgtcacatc tagcttttca atataagcct gaataaattt ttgcatataa aactccttta
     7981 tttcattata ccatattttc atcagtctca ttctccataa atattcaaaa aatagacaga
     8041 aaattcttga ttttgtctat catttatact ataatcataa tcactacaca aaaaggagat
     8101 tattatgaaa agaatcattc atgcttggaa taaagcaagc cttgtcaagc gtatcttgat
     8161 tggtatgctt tatggggaat cctaggactg acccttccta atctctcagg gattgggcta
     8221 ctcggggatt tattcgttgg aggtctaaaa gctgttgctc ctatcctagt ctttgccctc
     8281 gttgccaatg ccctttccca acatcaaaag ggacaagata gcaatatgaa aactgttgtt
     8341 ttcttgtata tcctatgata gggactttcg ccgctgctct tgtagctgta ctagcaagtt
     8401 tcatcgtccc tattgaaatt accctaaata gtgccaatac tgaaattgca ccaccagatg
     8461 ggattgggca ggtcctcagc aacctcttgc tcaaactggt tgacagccca gtcaacgccc
     8521 tgcttactgc taactatatt ggaatcttat cttgggcagt catttttgga atcgctatga
     8581 gagaagccag taaaaccagt aaaaatagta aagaattgct aaaaactatc gctgacgtga
     8641 cttctaaaat tgtcgaatgg atcatcaatc tggctccatt tggaatcctt ggtcttgttt
     8701 ttaaaaccat ttctgacaag ggagtcggaa gccttgccaa ctacggtatt ttattggttc
     8761 cattagtaac gactatgctt tttgttgccc ctgtggtcaa ccctttgatt accttcttct
     8821 ttatgagacg caatccttac tctctagttt ggaactgcct ccgtgtcagc ggtgtgacag
     8881 cctttttcac tcgtagttct gcgactaaca ttcctgtcaa catgaaactc tgccatgacc
     8941 ttggactcaa cccagatacc tattctgttt ctatcccact cggttctact atcaatatgg
     9001 ctggagtagc gattaccatt aacgttttga cccttgttac agttaacact cttggaattc
     9061 ctgttgactt tgccacagcc tttgtcctca gtgtggtagc agctatctca gcctgtggtg
     9121 cttcaggtat tgccggaggt tccctccttc ttatcccagt tgcttgtagc cttttcggta
     9181 tttctaacga tattgccata caagttgttg gggttggttt tgtgattggt gtcatccaag
     9241 actcatgtga aacagccctt aactcttcta cagatgtcct ctttaccgcc gttgccgaat
     9301 acgcagcaac ccgtaaaaaa taactcatca aggcaagcct gctcatgtct tgtcttttac
     9361 gcttttattc taacttatta ggaaattctt atgtctatta gccaacgtac gaccaagctc
     9421 atcttagcta cctgtcttgc ctgcctgctt gcttattttc tcaatctttc gtcagcagtt
     9481 tcagctggaa ttatcgctct cttgagccta tctgatacgc gtagaagtac tttaaaactg
     9541 gctcgcaatc gtcttttttc tatgcttcta gctctggcta tcggtgttct agcttttcac
     9601 ttgagcggat ttcatatctg gagtctcggc ctctatctgg ccttctacgt tcctttagcc
     9661 tacaagatgg gctgggaaat tggcatcaca ccaagcacgg ttttggttag tcatctcttg
     9721 gttcaagagt caacctctcc agaccttcta gtcaatgaat tccttctctt tgctattggt
     9781 acaggatttg ccttgcttgt taatctctat atgccttcac gagaagagga aatccagcac
     9841 taccacacgc tggtggaaga aaagttaaaa gatatcctcc agcgcttcaa atactattta
     9901 tccagaggag acggacgcaa ccgagcacag ctggtagcag aattagacac gcttttgaaa
     9961 gaagccctca gactggtcta tttggatcac tctgaccacc tctttcacca gaccgactac
    10021 catatccact actttgagat gagacaacga caaagtcgta tcctgagaaa catggcccaa
    10081 cagattaaca cttgtcacct tgccgccagt gaaagcctga ttttagcgca gctcttttca
    10141 aaaattgctg gtcaactgag ccagaccaat cctgcctctg atttgctaga tgaaattgaa
    10201 cgttatctgg aagtcttccg gaaccgcagt ctgcccaaga caagagaaga atttgaaacc
    10261 cgcgccaccc ttctccaact cctacgtgaa gccaaaacct tcatccaagt aaaagttgac
    10321 ttttatcaaa aatatggaca gtaatactct tcaaactacg tcagcttcac cttgctgtat
    10381 atatgttact gacttcgtca gttctatcca caacctcaaa acagtgtttt gagctgactt
    10441 cgtcagttct atccacaacc tcaaaacagt gttttgaact gacttcgtca gttctatcca
    10501 caacctcaaa acagtgtttt gagctgactt cgtcagttct atccacaacc tcaaaaccgt
    10561 gttttgagct gacttcgtca gttctatcta caacttcaaa acggtgtttt gagctgactt
    10621 cgtcagttct atctacaacc tcaaaacggt gttttgagct gacttcgtca gttctatcca
    10681 caacctcaaa acagtgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    10741 tcattgagta taaaaaagaa aacttcagac caatccacaa aaggtgaata tctgaagttt
    10801 tcttttattt ataagtaatc accataaagg ttaatagtag aacaaataaa gccaaactca
    10861 ccaataaagt gagcaccttg accaaggtgt tgctctgcca gtagcttggt ttaccaatat
    10921 tactagtggc atccatggaa aatagttgat tttgacgggg ttgtatagtt accaatacaa
    10981 tcaaagcaag agataggata atagctaaaa caattagtat gtcaatcata gatctacctc
    11041 aaaattccca gcaaagtaaa gagcaaacca atcagaatca tcaaacccag taaaagtgaa
    11101 aaagtcttac taatcttttc ccctcgggtt tctttttcct tcttgatggg tttttgtttc
    11161 aactcttcca tgcggccttc aacgtctttg taaaataaat cttcctctga catgttagcc
    11221 tcctaaaaca gtttgcatgg tttcctgata tctcaccaag tcaacataat ttgcatgttg
    11281 gccttgtctg ccaagtgcct gacgcatttg atcaacatct gaaagggcca atttaatggt
    11341 ctcaaccaaa gcagcaactt cactactttc aaatagatgg tctggagcga tataaagtct
    11401 attgtgaacc gtttgattaa atccaagaat caagagattg tgctcaaagg cctgacgaac
    11461 tgcctgcaat aactcattgc tatagttgat atccaagtaa atatccgaca gttgatacaa
    11521 ctcctgaatc ttctgtggac tagcattctg gtaaagaacc acattaggat agcgaagcat
    11581 gtctaagagc ttagaagaca tctctgtcac cgctgcgata cggaaggtaa catcaggcaa
    11641 ggcttctacg attgcttcta cttgctcaat ctgatctgaa ttggtcaaga ttaaggcgtc
    11701 tcgtcttagg aaattatcac gtttgaactg gtaatgataa cccaagtgca caaactgatc
    11761 atggtatttc tcgtcagtta actctaaagc gcgctcataa gtcgccttat ttggaataat
    11821 gatcttctta gtacgcacat tatcactttc caaaatcaac tgcatattac ctggaatggc
    11881 atcataaaga ggttcctgcc ataccaagac atccgagcca gatttatctg gataatgaaa
    11941 ggaaaccaag aaaggagtcg ctagagtatt aaagataagc tgactggtgt ctatttccaa
    12001 atcttgcaaa aagaaggtga taaattcaac tttatttgca aagtaacgca tggactgacc
    12061 aggcaaagtc aataagatat cacccgtcac atggttttcc aaaataactt ccttttgatc
    12121 tacgtcccga taggaagtca taatagcttg ccccaaaaca tcataagtgg ttttagcaaa
    12181 gcaagcacca aagcgattgt agtggtcaac ctgacgtact cgaccttcta ggtctttcca
    12241 gtctacctgt ttaaccaagc gagcctgcat tccatcagca taatgaatga cagccctctc
    12301 ctgcgtcaca tcttcaatac aagcagactg attatctcct aaaatttccc aaaaatctga
    12361 aacgggaact tggttaaaat agagaggttt tccatcctcg taacctagat aataggtaaa
    12421 aggagaaagc agaccatcag gcagaaaacc atctgcatcg atgaccactc caagttgaga
    12481 aagaccagta gcgactagac tttcatgtaa atctcgactt tcttgactgt aactatcata
    12541 aagttcaatc atggagcacc tcctctactg ttttcttcca cttttctaaa atttctttgg
    12601 tcaagaagcc ttctgcaatt tggtaagaat aggcacgcat agcttccaaa cgattttctt
    12661 gatacaattg acaaatctta gcggcataag cttgcttgat ttggtcttct acatggtcag
    12721 atgaacttgg aatcaaataa ccattttgcc catcctctat aaaggtctga ttaccataag
    12781 gtacatcaaa accaattaga ggtagacctg aaccaatagc ttccatcaag gtcagaccaa
    12841 atccttcgct ggtagaagcc gttaagtaga cctcatactg gctataaatc tgcgaaagtt
    12901 ccgcatgccc cttgagttgg atatagtcct ctgcctgatg atttgcaata atttctctaa
    12961 gcagagaatc ttctcctcca ctaccataaa tatcaaaggt taattcaggg atttccttac
    13021 gagcctcaat cacagcctta accaaccaat caatgtgttt ttctttggcc agacgtgaag
    13081 cggtaattaa agaaaatggc ttacgtccct gactttactc cgtcaaggaa tcaatactac
    13141 ctacaggaat ggtaacaatc tttggctgat gctgagtata tttggcaaat tgctcttgta
    13201 gaacttcatt ttgtctatca gtagacacga taaagaagtc aaccttatct gcattggtaa
    13261 actgatagtc ataatagtta ttccaaagga tgtagtcctc atttgtagca ttttcactat
    13321 aatgctccgc atgaacaact accgctaaat gtgctgtctg tgcttcctca aacacaacct
    13381 gaccaatgcc tgtctcccta tcgagaatga ccaaatcaga cttattcaaa ttcaaagatt
    13441 tcataaaggc acgcacaaaa gcttgctttc catagaaaat cttatccttg aaatgataaa
    13501 cttcttcctt cccttgattc atcaagatat catagactgg agtcccgtct tcattgtaaa
    13561 aagttcgttg gtataagact gcaacattgt ccttgggagc aaaatactcg ctacaataac
    13621 gcgtataaga aaagtaatcc ttccgaatca ggtttccctt aaaaacatac tcggcatgtt
    13681 gaaccaagtc cttgttctca tcaaccaaat aacaggttac aaacttatct tggtcaaaaa
    13741 agaagacacg taaaaccttg ccattttttt ctctgtgact ttcttcacca ccaaagtaag
    13801 ccaagacatc atccactgtc acgctagtag gcgcaatttt gatatctgtg aaatgattat
    13861 aaagccagat aacctgatta tcatcaaaac caatattggc tgttaagtgc tgaatattat
    13921 cggctaaaat catatctgta aagataaact tagaggacag atttaatttc cgaaaaacac
    13981 cagcacgata ggcttgagcg tattcaacac cgctactagc ccaaccaatt cctaaattta
    14041 tattgtaaat tgtcatattt tctcctctta tggaaaatga gtcacgattt caccttttgg
    14101 agtgacctca accagcccca tcaggagatt acgcaccata tccgcacgga tttgttcttt
    14161 catagcttca aagcccgcgt aggcttcttg atagtactct acgattggat ttttctgact
    14221 agcagattga ccaccgatag ccatggatag ctgttgtaga tagtctacct gctctaccca
    14281 gttgtcatca atggctttaa gcagtgaaag tcgtaaaaac tgttcatata agtcatgttg
    14341 attaagtaat tctttctttt cagaaagttc tttatcaatc acctgcttca taaaactacg
    14401 aactgcagtt ttgtcagtta catctatata atctggaacc tctttaacat gaaaactaat
    14461 attggtcaca ataaagtgaa acagtaattc acgactagca tagtgatcag ccgctacctc
    14521 ttctgtatat ctctcaatga tatccacaac aacatcctct aagtcacgag aaccatctat
    14581 tagacgatta cgctccttgt aaatcatatc ccgttgaata ttcatacttt cagcatattc
    14641 tagagtctga cgacgtgccg aacggccagc actatcactg gcatgctgag ccttttcgac
    14701 tagtttccgg tatttacgac ctttcaatac ttccggttga gtcatatctt gaacctgata
    14761 gtctttgtac tttttatgca cccaagatgg accaaatttc ttgataacat catcctctaa
    14821 ggatacaaaa aatttactca taccaggatc tccctgacga ccagaacggc cacgaatttg
    14881 taggtcgatc cgctgacttt ccatccgctc agtcccaata acaatcaagc ccccaagctc
    14941 tgcgactcct ttaccaagct tgatatccgt accacgtcct gccatagagg tagccactgt
    15001 cacagccccc atctgacctg actcggagat aatctgagcc tcacgcgccg cattattagc
    15061 atttaggaca ttatgggcaa tcccttcacg aaacaagaga gacgaataga gttgagacat
    15121 ttcaactgag cctacaaaaa cgagtaaggg atttccctta gcatggtatt gcttgatgta
    15181 ctccaaggat gcatacactt tttcaggtaa agtgatatat agattatctg gatagtcaat
    15241 ccgttgtctc ggacgattgg ttggaatgcg tactacagac atattgtaag tttcaataaa
    15301 ctctttttcc gcgaccttac ctgtccctgt cataccagat atcttattaa acatcttaaa
    15361 aagactctga taggtgatcg aggccatagc ccgcgtctca ggagataatt tgacatgttc
    15421 cttggcttca atagcctgat ggagacctcc ttgaagttta gtcatttcca ttagacgccc
    15481 tgttccctta tcaaccagta ccatctcatt tccacgaatg atatagtcct tatctttagt
    15541 aaagagctta tgagctcgaa tcgcataaac caaatgacga gcaaaagacg catgctcttc
    15601 cttgtataaa ttatcaatcc ctaggaaatt ctcagcagac ttggccccct tagtagtgag
    15661 ccaaacctcc tctttctcct ctttaaagat ataatcctct ccttcgacca aggttgttac
    15721 aagtgtatca atgatcgcat agtaattaga ctgaacacga ggagaacccg caataatcag
    15781 aggagtttgt gcactatcaa gcaagatatc atcaatttca tcaataatca catagttaaa
    15841 cggtcgtaaa aacttacctt cttcattcga ggctaggtta tcatttagat aatcaaaacc
    15901 taaattacta ttggttgtgt agatgatatc cgaagcatag ataagcttct tttcttcagc
    15961 tttcatttcc ttctttggat cttccgtaaa tggtacacca atggtcaatc ctagaaaacg
    16021 ataaacttgg cccatttcct cggcatcacg ctttgataaa tactcattag gagtcacaac
    16081 catcactcct tctcctgaaa aagcgttcaa atagacaggc atggtagctg tcaaggtctt
    16141 accgtccccc gtattcatct cagcaacatt tccatagtgc atgacaatag ctcccatgac
    16201 ttgaacatca taggggaaca tccctaaaat ccgcttatct gcttcacgca ccacagcaaa
    16261 agcttcaacc aaaatatcgt ctagactttc tccctcggaa agacgctgac gaaactctac
    16321 tgttttagct actaattctt gatccgaaag agaggacatc ttgcctttca gggcattaat
    16381 ctgctttaaa atctttttca ctttcctaag ctggaaatct tgacctaaac gtctaaacac
    16441 ttctgatctc cttgatagaa aaatgataaa aagttaagga ctcaaatcca gcacttaaaa
    16501 gagaaacttg ataagtataa ctatcttctg gataagtaaa tatgaaatct ttcgcttttt
    16561 ctaccttttt ttctaaaata tcaccatagc ggtcaaaaaa agttatcttg gtataaactc
    16621 cattttcagg ctgacaatca aaaaccagtg atagttgata ctcctgcttt ctttttaata
    16681 agggaagctg aggttgggtt cgtgcagcct ggtaattgac actagaaaac caagtcttta
    16741 gaatctcacc agatggcaat agaggattat acagacgaac acttttgtca aggtaataag
    16801 atacagttgt tccatacata taagtcccac caacttctcc ccaataaata gactgtctct
    16861 gtgtaataat catcttttct cccttccaaa accagtctct aagaccattc tataaaagtg
    16921 caaaaaccaa gaaatattgg tatctgtatc atcattgtgt cgtccagcag ttcctttaga
    16981 taaaatcttc gcacctgtat tacacagata agacactaat tgttcatagg cttgtggatc
    17041 catttcttca tctttcatat aggataaacc aaaggttgtc tttgaaaaat ttgcttgttt
    17101 aaaaattttc caaaaacgct gatccaactc cgtcatatct tgagaacttg tcccacctgt
    17161 atgatgaatt aaacaatcaa aagctaagtt agagacaccc ggtgcgtcca aacgtccacg
    17221 actagctata gttcctaaat tagccaaggg cttaccaact atgatggcat ggggttcaaa
    17281 agaagcacca taatagagag ccggaaacgt tcccatagaa agacctgata aaatcaaatc
    17341 cttatgatca aagcctaaat aatcaagata gtgagtgatc gtatccttta cttttccctc
    17401 tagctcatcc gttccgagat aaaaagctcc cccctctaaa cgtggatcag aaaataaaat
    17461 gaagggacat ccaagagttt tcatcataaa gtaaccctcg aatccttctg caggtcgata
    17521 acctgcaaaa tagacagtca aaggcggttt aaaatcacct ggatggaaga aatagtttat
    17581 ttcatcacgc ttggaatcat gtaggatatt tccaccaagt acaaacttac caaattgttt
    17641 tcgactccat cgttggtgaa gattacctag tttgatagtt ccacgacctc ttgcttcaac
    17701 agatatcgag agaaagtagt ctccgtctcg actatccata aaaagtgctt gctccaagtc
    17761 tttttcagat actattactt cttcaaagaa atcatcaaca gacccactcc acattttacg
    17821 gattactaaa cgaaagtcac aattgccttc cttctcatat tcaagccaca actcaatagg
    17881 gagtgttttt tgcaccataa tattataagc ccaataggca agctgggcaa aatcttgccc
    17941 aaactcacct tccaaactga cataatccaa tccttgataa gaaatagctc ctgtaaaatt
    18001 tggattgact tgtatcgtcg gaggaaagag tttatcacca tacccaccgc caaaaagaga
    18061 tttacttaaa tcattgatta gttgttgggg acttaaaaaa tcaattgctt gtgcacatcg
    18121 tttttttaga aaatccacaa cctctctatc atttatttgt agattctggt tataaaataa
    18181 agtataaggt tcaaaatatt ttacatagga aaataagtct ttagcatact gaccatcttc
    18241 tattaaaact gcatgaaaac ggttaatatc ctctttttca attatttcac gaagagcttc
    18301 tgatgagttt gggtaaaaat aataccaact catattttca ggtatgtcat agtgattttc
    18361 ccaattggca agtcctatct gtaaaatatt aagttccttt gacattttta acctcctcta
    18421 tccatttctc taattttcca agaaattgtt gtcctgtgtg ctccttaatc ttatcaattg
    18481 aatatatcaa ggactcattc cactccttca acctatctgt gtaataatgt gcagccttag
    18541 aaaattctgt aacatctgct aacaaataac cattttttaa atgttcaaca tagacggttt
    18601 caactaggtt gatttgagga attcctgcac taatcccagc aatctgtgtg tagagatgag
    18661 gatgtctatt taaatccaca atcaaacgga caaattctag tgtttttatc aaatctaact
    18721 catcattcaa gttaacaaac tgtaagcgta agtcctggtg ttgattttct tccagaggat
    18781 tttctgcatc accataatca atcgcctttc ccagattttc ggattgaatg ttttcttgga
    18841 tgaaagactc aacaatccct tcaacctcat tcatttgctc ctgactagca gcaaaggctc
    18901 caaaaatcac ctcagtatcc ttattttcag cgacaaagga caagacttga agcagagctt
    18961 gattatcaat cccctgctca aaatccagtt gaaaataaat gatggattct ttcttagttt
    19021 ggcttcgtcc caatcgtaat cgggtgtcaa aagatgataa atgataacat tgatgcattc
    19081 gttcaggata caactcctgc aacaatcgta aactatcctc tctatccacc aaaatcaaat
    19141 ccgatttttc aaaagttaca tctaaatccc taaaggtatc ttgagaatta cgtccaatga
    19201 acagactcaa cagtttagga ttagtactag gtaaacgatc tagtaccaac tggtcatgat
    19261 gagaatgaga aggaagcata aaaatatcct gatccttcac atacgtttgc agataattct
    19321 caaaaaattc tgccaccaaa tctcccatat tttgataggt aagcatttta aagcgataac
    19381 ccaaaattgg attgacttct acctgtcctc cttcttttaa acgctctcta aattgccaaa
    19441 ctcccttagg attcaaatat tcttgatagg ctgcttgccc atcttcaaaa aaaataatac
    19501 tcgatataaa ccctcgatca tccatgatat ggtgcatatg tatttgacca ttcggtccaa
    19561 aatactgtat atcactgatg aaaccttcaa ctccatgttc aaccttagca aatttcttcc
    19621 catttttttg aacgataatc gtaaagggac tataaataaa ttcacagtca tcatcccact
    19681 caatatctct aatgcttaaa acttgggtat ggagattatg aaaatcttgc ataacatcaa
    19741 aaacggaata agtatccgtt tctaacacac catgtctata taaaaaataa cgtagatgag
    19801 gctggtaagc taatactaat agacgagaat ctatatcttg ctcttgaaag agccgaatct
    19861 ggtgaaaggt atcatcaaac tctagacgaa aatgagaaaa ataccatgga gtgatatctg
    19921 catgccatgt tctttctgac ccataccaag ctggaataaa ataatacata aaagtctcct
    19981 aaatcaaagg tctataggtc tcatttagcc ttaaagcctt gacctcgtct ctaatcgtaa
    20041 aaatcatgcc cccgaacatc ataaataagc ctggaatcat tgccaatcgt aataactttt
    20101 catcaaacaa aacaaaaagc atgggaccac ctgccataat cacattaaag agaccaccta
    20161 tgactgagaa acgaaggacc aatcgattaa taaatcgact agtatccgca cctggataaa
    20221 taccataaat gtattctcca gattttttca tacggtctgc aatctcttct ccattcatcg
    20281 taacaaaagc aaaaatgata ctaaataaaa ataagaccga aatataaaca tagacccaca
    20341 aaggcttccc aaccataaat tcctttgata aagccgctag ccctgaatga ttagggaaaa
    20401 taaatcccaa caagatgaac aaataagctg gtacactaag aaaactcatc acatacatat
    20461 aaggcatccc acctgcagga ttcaacatga tttcgagata agaatagcgt ttaaatcgat
    20521 tgtgtaagcc aattttatta acaggaacca aatagcgagc tcgatacata agggcaagca
    20581 agtaagaaaa tataatggtc ataaaaacaa gcaagacaac aatccctgta gggatataaa
    20641 ccagtttaaa agtttcaata acatcctgag ggatatttaa aacaatgctg gataggagga
    20701 ttacaataga acccccaatt cccatgctcg catttaaatc tgacaaccaa acaagaaaaa
    20761 acgttcctgc tatgagtaac aaggtattca ttagagcaac caaaattacc gagtaggagg
    20821 attgtactgg caagctcaag ctaactgcca aggattgaat cacagcaatt agcaaggtca
    20881 gatacattct tcgacgatct tgaatttcaa tcgctgtaga acttagcccc aattttttag
    20941 aatatgaaaa catctgccac aaaatcatag ctgacatcca aggggataat ccaacagaaa
    21001 aaattgacaa acttcttaga tttccacctg ttagggcggc tgagaaggct agataggctg
    21061 ttgaacctcc taaaaaatct ttagtattta ggtcaacaaa agggagagta atacgacttc
    21121 ccaatacata gataaacagt agaaataagg taaatagtcc tttttttact gctattgacg
    21181 aataaatctt agtcataaaa cactcccctc accttcattg tttgtgatat ggtaaataac
    21241 aattctttta tttcaacttt taccatttct ttgttctgca tcaaaaaaca actttaatct
    21301 gaaacaaata tctttatatt cctcagtatc tgttaattga tggtattcta aagtttgctt
    21361 ataatctttt aaaagattga caaatcgaat acgcagaacg gagacatcca aaccagccaa
    21421 gatacaatcc gatattttct tagaaaacac ttcaacaata tctcttgccc aggaaagatc
    21481 aaattccgtt ctcatgatgc ttcctgaacg tcttctatac agatagagat tatcgtttat
    21541 aaagacgatt ttagaggcta aaagataaaa gcgatgcata gttgcttcat catcaaagcg
    21601 gcgaccattt gaaaagtgaa cttcattgaa taattctttt ttaatcaact taaatgtcgg
    21661 caatataaag gccgagctat tgaatttcca atctcctgct tgacggttca taatttcttg
    21721 tatagctaat tcttcgacgc aaaaatcttg ccctgttaca taaaaataaa aattcccgtc
    21781 actttcgtca taattatagt aattccctat aacaacatcc gcatcctttt cttggacttg
    21841 ctgataaaga gtttcaatca tattttcttt tacgatatca tctgaatcaa caatcgtgat
    21901 gtactctccc ttagctacac taatccccat atttttagct tgtgctgccc cccccttatt
    21961 ttcttgatgc aatactcgca cacgattatc ttgcatcata aaagcatcac aaatttcccc
    22021 agaattatcc gtagaactgt catcaactaa aataatttct atattttgat aggtttgctt
    22081 cagaatatgc tcgacacact ccactaaata ttttcccgta ttgtatatcg gtaccacaac
    22141 actaattaat tcactcatta ctctatctct atattcttca ttctatccac taaatcatct
    22201 ggtctctcca cagaaaaaat accgtcatag agtccatcat ccatactttt acgtgtgata
    22261 tcaaaagcga agattttctt gccactttct tgtgcccttg taactacatt aaaaacctct
    22321 ccacctgtat taatatctaa ataaactata gaatcgtcta atagccaatc aattctacta
    22381 tgtaatacat tttgatatac tgttacattc gtatactgtg atagagaggt cagctcctca
    22441 gaacaatcac acggtgcagc caaatgaaaa tgccaatcag gtaaccgttg tactaaatac
    22501 tctaaatgtt ttatatctgc actccatgtc acaagcatca cttgtttttt agactgattg
    22561 cttctttcaa aataatttaa atcggaacgt tgaaaagcaa tctctgacca atccaaatct
    22621 ctataaaccc accataattc acgtagtcta gatatactat atgtattcca aggtttatca
    22681 tgactagcat agtgaacaat tgtaggtgga ttgtcatcta gacgttcaca ttcttgagca
    22741 aggtgataaa tatcaacacc caccatataa ttatatgttt tatctaaggc tagccaatta
    22801 tcctcaaaat aaatatttaa aatactctga tccccaagat gaacaacttg attctgctcg
    22861 gccgctaatt ccaataaact attgactata gaatgttctt tccattttac aacatccatt
    22921 agtaacatac cagtattaaa tccagatttt cgtccttcat aggcatagac atcatcaaca
    22981 gcaccaattg aatatccttt gagatctatc tcaaacaaag tagctagttc cccagttaca
    23041 atgatatcgg aatccagata caatacccta tcagattcaa ccacttctgt cgcaaaaaat
    23101 ctaaagtaag aagcataatt tatatgaggt cctgttttgt agctttcaaa aagttcttta
    23161 tcaatgtgta cactgcgaat tgtagaattc acaacttcca tttttctccc caataattta
    23221 aaccattcag gagctatatc actgttgaga atataaaaat caacatctct attgtgatac
    23281 aatacagact ttatagtcgt ctctaaagga ataagatagg cattatctgc cgctaatact
    23341 attgattttc tcatactgtt ctctacctca tgtaagatct gattgctgca accatttttt
    23401 tcggaatgga gcttggatag ataccttcat atgaaatctc agaaagattt tcagagcaag
    23461 tattgtcgaa agctatcatt gtttttttgt acttaagcac aaactcatat gcatcttcta
    23521 attttcgatc atgattcaaa tccaaataca aatctgaagc tattactatt tgttccaata
    23581 acattggtaa ggaatttgga tatacggtaa cattaggaaa acgcgttaaa gctagtagtt
    23641 catttgccat atttgtataa gcaacaatat gaaaatgaac ttctggcaat tgctccgcca
    23701 aataatcgat tttctcgaca caccaagaat tcgttaaatt aacacattgc aacttaaata
    23761 tttgtgattt actaggatac ttcacactct ttgaaaacca ttcatttaaa ataacagacc
    23821 aatccatcaa agagtattcc caccaaactt ctcttagacg tccaacagaa aattgattcc
    23881 aaggcttatc ctgagaaata tagtgtaaaa ttagtggcag tggttcgagc ggaatatcaa
    23941 aaatgaattg atgtttaaag gctgccgccc cataatcata tcctatttga aaattatatt
    24001 gatcttcaag ggaactatat tgatctttaa acaacatatt caaaattgac tggtctcctt
    24061 cttccacatt ctcatgttct ttttctgtta agtcaatcaa tttttgtcga atagtttcag
    24121 atccccattt tttgttgtta atcaagagaa caccagcatt gaagccgact cctgctccaa
    24181 agcaagaacg agctgctgcc aaataatttt cacctaagtc taattcaaac aaatcggtca
    24241 aatcaccagt cacaatcaaa tcactatcta gatagagaac tttatcttct gttacaaaat
    24301 ctggaataaa atagcgtgca aaggtcatat gattgatatg aggcagttta ttagaccagt
    24361 tcattgtata ctgtgagcca atcaacttgc aatcaatcaa gtcgcccccc atctcttgta
    24421 aatatattct tatttgacta aaccattcct ggggaatgtc ctgattgagc aaataaattt
    24481 tcaaatgact attgtgtcta cagagtgact tcattgccgt ttcgatttgt cgaatataag
    24541 cgtaatcacc tgcaaatact acagcgcgtt tggtatttct cattttaaat ccttatcatt
    24601 tattttaaat agtctagttt aatattcgtg caacaatctg actgttatag gtttcatcat
    24661 caataaattc aatatcttgg tcgaaattat gttctgcagt atgtttatga gaaaatttaa
    24721 ccttagtttt agctcccatt ttcatccatt catactctga gtcaatatgg cctacatcca
    24781 aaacttgata gcccatctgg catagattat aactcagaac ttttgctgta ggacccagca
    24841 tacataaaat aaggcgattt tcagcatgtt tcataatttc ctcttgaatg ttatcgacaa
    24901 cggaataagc attatgagat ggacaaataa tccttttcac agatttgacc ttatcaaata
    24961 aatcatttcc aaccccagag cgagatgtaa tcccctctac aatcagaata tccctattct
    25021 cccaaatact ctttagcttt tcaaattgtc cttttgcctt actcttatct tcataatcaa
    25081 tgtatggacg cgagataaag gtagagccat accatgaacc cttacacaac tctttataaa
    25141 aatccatata aacattcata tgttctttcc agaatggtgt agcccaccaa gtaaagacaa
    25201 aacgatcgtc aaaagcatca ggtaaacaaa ccactaattt ctcgtcactc tcaagaccca
    25261 caatatgttt taattggtta gctaactcta gatcatgatt ttgataaggt ataggcaaac
    25321 cccacatcaa attgacttct ccgtctccaa aacgaactaa tgaggactta tttttgataa
    25381 cataatccag agtctgatca attccgataa ccttgattgg cttctctggt tctcccaaag
    25441 tctctccttt tatcaatgca tgaaatgctt gaagaagcct ttctggatgc tcacttgaat
    25501 ataaatgttg accatgattt ccattttgtg aagtataaaa tgccagcatt ggtttattca
    25561 atgatgatat ctccttgaca acctcactag tagaattgtg taggttaata tccaaataaa
    25621 catccatttg agatttgagt tcttcaaatt gatcgctttt cacttcagga tatagcttaa
    25681 catttttata tttttttgct agttcttgta acattggtcc cataactgtc caagctgcga
    25741 tatggaatgt taccatagga aaattcttaa caagataatc tatcttttgc aattcttgag
    25801 aatttgtaaa tgttaggcaa tggaaatcac taccttcata acaacttagg aatcttccat
    25861 ctcttctgta atctttaatc gcttgaacca tgactgaaac ttcatctttt ttgaatacta
    25921 gttggccagt attcccatgt tcagtcgtat caaatgatgg aattggcttt tctaagatct
    25981 tcatatcctc taaaatagta cctaccacat gactgtagtt aatgtccaga tataaatcta
    26041 cacttctctc cagcttatct aatacaggag gaacaatttg tggatgcaat ctcacattat
    26101 tatatacagc taattgtttt aatttatctc ccatatccgt ccaagctgcg atatgaaata
    26161 ccacctcagg tagagctgta actagctctt ctattccttc taaatcttgg gaattcgtta
    26221 aggttaagca agaaaattcc ttatctagag gcgatattag ttcaaattct cccatatggt
    26281 gttgtaaaat ctgactccac tccaaatcat ggaattccca ccataaatca cgataacgat
    26341 tggctatcaa ggtggtccag ggttttctgt aggtcgtaaa atgaatcacc actggtttat
    26401 cgttaaaagc cagatgttcc tgccaattat tatacaaagc cacaatatca tgccctactt
    26461 gtaaattata agctcgacct agctctaacc aatcatcttg caagacttga ttgaaaatcg
    26521 tttgatcacc attaaaatgc tcgaaacggc cttcttcaac ttccttcatt gtaacaatgc
    26581 tctgttcaat tagtcgttct tttaatttct cttgacgcca ttttttattg ttgattaata
    26641 gaacacctgt attaaatgta attccatctg tatctttaac tgctgcgagt gatttttctt
    26701 ctaaacaaat actaaataat ttctctaaag aagtatttac aatcaaatca ctgtctaaat
    26761 ataaaaccgt atcttcttgg atataatctg caataaaata tctagcatag gtaatgctac
    26821 taatgtgatc ttgcttttcc caatcttgaa acacagtttg ttcaggtagt ttaacatcga
    26881 taatctcact acctaacatg cgagctattt ttcgtggttt gcgaaaccaa tctggcataa
    26941 tatcttgatt taaaatataa atcttaacat ctcgattgtg gtataaaata gattttatgg
    27001 ttgtttctaa ctgcctgatg taattacgat caccagctaa tacaattgtt ttaatcatct
    27061 tgttctctta ttcaactccc aaatggtaaa ttgcatctac caataatttt ttagtaaaat
    27121 aaccttcttt tagcaaataa ctaaaggttt ttatccgatt cgtcatttct tgatattctt
    27181 gtagattcat tttatcaact atctcatgaa cttcctctag actattcgcc acaaagccta
    27241 agccttgatc tactataaat tcagcagttg acaagctact tggtacaatg actgggatgc
    27301 ccgctgtcag ataggtactc accttatgag atatattcaa ggtatagtat tggttacttt
    27361 ctccctcatt ttgatgggtt ccccagacaa ggccaaatcc accctttgat aattctagca
    27421 acaattcctc atcttttttc catccttcga tgctgagatt tctagcacta gaactagctt
    27481 cccctttatt tgaaaatact ctcaaaggcg tatcttgaga ccaattttgt aagtctggaa
    27541 aacgctctaa acttccagca aaaaaaagtt cttttttaaa agcaggggtg tataaggata
    27601 aatcatgagg atgatcccac atcccttgaa caagaatctt cttagtcgtc aatccttctt
    27661 ccatcaggcg tgttttcatt ctctctgatg gcactatcaa aacatctgat agattataca
    27721 tgtacatata gtctttcatg agataatagt tactatcaaa catgagggga acaacatcat
    27781 ggataaagca aataattttc acctgcatat cctttagctt gtcaaacaag agacgatcaa
    27841 attcaaagcc attccaggtt ggagactgaa agactaaaat atccccaata gagatactgg
    27901 ccataatacc atccagacgc ttattcattt cagaaggact atctgaagca atgttgtaaa
    27961 aataaatacc aacctctcta aatcccagtt gactagctat cttttgaaca gcattttgag
    28021 ctaagataac cgtactatca ccagccatgc cgtataaatt tgttaaatgt aatttcatat
    28081 tacgctatct cattttttat tactatctac ggaagtaaag acaatttttc catcattctt
    28141 ctataaatct ctgtgaactg catattttgt tcttctaatt ttgctatcac tctttgtaat
    28201 ctatttttat aaatcaaaat atgattggtc aagtcatagt ctgaacttgc taaaatagct
    28261 atcttttctt ccctagcccc aatttcatca tacatacgct tttcactcca tgtattcgat
    28321 aaagtatcag ataaaccaac acggtaccag taaacacaac gattcaaata gactatcctc
    28381 gaagctctta gaagtacctt ccatgtccag taagtatcct ctgcaatttt tcctatagga
    28441 aatggtaaat cttgtagtaa ctctctcttg aataacttca agacagctac agtccagttc
    28501 ccatttctga cttcttcgac accttcccta tccatgattg ctttaccttc tatcacttcc
    28561 agagaatcat ctggatccgt aacataagtc atatacacat agcgtgtttc atcataagaa
    28621 ttataacgcc cgatactaat atctgcgttt tcctttttca aagcaccata taatcggtct
    28681 aaagcatcat gttccaacca atcatcagag tctacaaaag taatgtacgc cccccccccc
    28741 cgaacattca atacctaggt tacgagctga tgaaagaccg ccgtttgctt tctcaaaata
    28801 tttgaaacga gaatctttct ctacaaattc ttcacatatt ttggatgaat gatctggaga
    28861 gccatcattg attaataaac actcaaaatt ttgatacgtc tgattctgaa tgctatccaa
    28921 acacattcgc aaataattct caacattgta gattggaact acaatactaa ttaattcatt
    28981 tcccatatac taactttcct agacttgatt tattctattt ccctcttaat ctcttctttt
    29041 tacacaaaga ttgccattat tataaactac actgtttgat ggaatatcat tgcgtatgag
    29101 acaacctgct ccaataatgg tattatctcc aatcgtcact ccttttaaaa tcgtgacatt
    29161 acttcctatc cagcagtctc tgccaactct aatcggcgct gtagtccact gccacttttc
    29221 aatcttttca gcggtataaa tatggtcgtg atcataaaaa cgaacaccct ctcccatcat
    29281 ggtaccagct ccgatttcaa ttctttccat acagttaaaa ctacaagagt tgttgataaa
    29341 aacaccatca ttcaggatta acttaccaga agagacatga aaattttcaa aatttctaca
    29401 ggcgacattg gctcctacaa tgaagtgagc cttatcatcg attttaaaga cattccaagt
    29461 cccatcttga atgattttct cttgatgatt ggtgcctact ctgacttcat tcagatagtc
    29521 tctcactcta gaaaccaatt tgtctggtgt acttgataga aaaacttcct gcccctgatt
    29581 tccatggact gtattgtcaa atgcaaagac agattttcca gcctgtacaa acttggagac
    29641 aatagcatct acttcttgaa agtgattgat atctagtaaa aagtcacagg tatcgactaa
    29701 aaagtttagc tgttcttcat ttgtaatcgt tcggagacgg acattatagt tcgtttctaa
    29761 gctacggatt ttctcggaaa attgaacagg tgctgcaata tgaaaacaga tatttgacaa
    29821 ggattcaagg agataatcca actcttcaat ctgatcacta accgtcaaaa tcagagcatc
    29881 tcctactaaa tgatttttct tcatttgctt atttctctca atttctcaat cattgcttga
    29941 acttggtcaa cagcatatgc ctcctgacct acttcatagg ttttagtatt ttcaaaggat
    30001 aagataggct tgccaagatt agcaaattga tcgagaattt cttctgtctt ttcgccatga
    30061 ttaatatcta aaagtacttg actggtttct accaattcat tatcgacatc taccaaatag
    30121 tgaattccgt taaatatagt cacgtttgga taaattgtca tctgagccaa tcgatcacta
    30181 actattactc tagctgctat cttaaactga atatcagacc atattgaacc aatgtctcaa
    30241 tttgttcaat atggtctgag gcagtataga ttagacaagt gaaaggttcc tttattggat
    30301 agatgtgaga tctttgtaat ggatgtaaat gatggttttg tcccaattct gtccattcaa
    30361 gcccatgata gtaccaccaa acttcacgat aagtttgggc cgccaaatct ttccacggtt
    30421 ttctatggga aagatagtga ataatagcag gataatcctg accctcaggc aattgataat
    30481 cagcaaactg tttatgaatg acaatatgat tataatcaaa atccaattcc agccatttat
    30541 gttcaaaaag catattcaag atgctctgat ctgcctgatc caccttatca tgccattcat
    30601 tggttaaatc aattaatttt tgggtcatat tctctttttt ccaaaaagca ttgtttacca
    30661 agagaacacc ggcattaaag atttcttgac caaaataagc tctgccccca aaatctctaa
    30721 cagcagccaa aggataatct tgtaagtctg tagcaaacaa gtcatccaga tttttcgtta
    30781 cagctagatc acagtccaag tagagggcct tgtcttcttg cacgaaatca gctatgaaat
    30841 agcgtaaaaa gactgtgtaa ctaatatccg atttataaca tgaaatttgc tcagaagtta
    30901 cccgacaatt aataatttct gagtcaaact tctctaatcg cttatttaat tgtttgatcc
    30961 attcatttgg aaaatcgcta tgaatcaaat aaaaacgaag cgagcgattg tggtaacaga
    31021 tagacctgat tgtcgttaaa acttggtcta cataggcata attcgccgct aggacaatgg
    31081 ctttcttttc acttgattct tgtaccgtta actgatttaa aagtcttttt ttcatttcaa
    31141 actctttata cgttgctgtg tcagataaac cactagcttg accgttggcg agactgaatt
    31201 ccaacatttg acgataaatc gccaaatgct tttctaaagg gtaacccata ttagctagta
    31261 gcgtaatgcg ttcggacatg gcatcaacca atgcatgcat ccacttttct gtccaaactc
    31321 ttgataaact accttttcta atccgattat tcttcatcat cacgtttacg gcgtttcgca
    31381 aacaaaccca agccagtcac agctgccaaa gctccaagga gtacagatga cttggaagct
    31441 tctgtacctg tatttggcaa ttgctgtctt gacttacctg ctgaagttga cgcgcttgcg
    31501 cttgttgatg ccgattcaga cgctgaagct gaggcacttg tacttgctga agctgatgca
    31561 ctcgttgacg ctgactcaga agctgatgtg cttgctgaag ccgaggcact ggtgcttgct
    31621 gaagctgacg cactggttga tgctgaagct gaggcgctgg ttgacgctga agctgaggcg
    31681 cttgtcgatg ctgaagccga cgcactcgtt gatgctgaag ctgaggcact cgttgacgct
    31741 gaagctgagg cgctggttga cgctgaagct gaggcgcttg tcgatgctga agccgaggca
    31801 ctcgttgatg ctgaagctga ggcactcgtt gatgctgaag ctgacgcact cgttgatgct
    31861 gactcagacg cacttgtgct tgctgaggct gacgcactcg ttgatgctga ctcagacgca
    31921 ctcgttgacg ctgaagctga cgcactcgtt gacgctgaaa ctgaggcgct tgtcgatgca
    31981 gattcagacg ctgaggtgct tgctgaggct gaagcacttg ttgacgctga ggccgaggcg
    32041 cttgtcgatg ctgaagccga cgcactcgtt gatgctgaag ctgaggcact cgttgacgct
    32101 gacgtacttg cactcgttga tgctgaagct gaggcactcg ttgatgctaa ggctgaagca
    32161 cttgtcgacg ctgaagctga cgcactcgtt gacgctgaag ctgaggcact cgttgatgct
    32221 gaagctgagg cgctggttga cgctgaagct gaggcgcttg tcgatgctga tgctgatgcg
    32281 cttgttgatg cagattcaga ggcgcttgtc gatgctgaag ctgaggcact cgttgaggct
    32341 gaagctgagg cactcgttga tgcagattca gaggcgcttg tcgacgctga agccgacgca
    32401 ctcgttgatg ctgactcaga cgcacttgta cttgctgaag ccgacgcact cgttgatgct
    32461 gagactgatg cgctggtact tgctgaggct gacgcactgg ttgacgctga agctgatgcg
    32521 cttgtcgatg ctgaagccga cgcactcgt
//
LOCUS       DAVHSL010000024        31943 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000024 DAVHSL010000000
VERSION     DAVHSL010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.024"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(216..1778)
                     /gene="guaA"
                     /locus_tag="VVR39_001106"
     CDS             complement(216..1778)
                     /gene="guaA"
                     /locus_tag="VVR39_001106"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU6030605.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1920..2618
                     /locus_tag="VVR39_001107"
     CDS             1920..2618
                     /locus_tag="VVR39_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6030606.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2661..3557)
                     /locus_tag="VVR39_001108"
     CDS             complement(2661..3557)
                     /locus_tag="VVR39_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6030607.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILTYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(3566..4501)
                     /locus_tag="VVR39_001109"
     CDS             complement(3566..4501)
                     /locus_tag="VVR39_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU6030608.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4498..5223)
                     /locus_tag="VVR39_001110"
     CDS             complement(4498..5223)
                     /locus_tag="VVR39_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU6030609.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5307..5942)
                     /locus_tag="VVR39_001111"
     CDS             complement(5307..5942)
                     /locus_tag="VVR39_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU6030610.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(5944..6771)
                     /locus_tag="VVR39_001112"
     CDS             complement(5944..6771)
                     /locus_tag="VVR39_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6030611.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGLKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6793..7129)
                     /locus_tag="VVR39_001113"
                     /pseudo
     CDS             complement(6793..7129)
                     /locus_tag="VVR39_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(7130..7858)
                     /locus_tag="VVR39_001114"
                     /pseudo
     CDS             complement(7130..7858)
                     /locus_tag="VVR39_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8371..8982
                     /locus_tag="VVR39_001115"
     CDS             8371..8982
                     /locus_tag="VVR39_001115"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6030612.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9027..9755
                     /gene="rlmB"
                     /locus_tag="VVR39_001116"
     CDS             9027..9755
                     /gene="rlmB"
                     /locus_tag="VVR39_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU6030613.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9794..10705)
                     /gene="trxB"
                     /locus_tag="VVR39_001117"
     CDS             complement(9794..10705)
                     /gene="trxB"
                     /locus_tag="VVR39_001117"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU6030614.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10771..10995)
                     /locus_tag="VVR39_001118"
     CDS             complement(10771..10995)
                     /locus_tag="VVR39_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU6030615.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11073..11816)
                     /locus_tag="VVR39_001119"
     CDS             complement(11073..11816)
                     /locus_tag="VVR39_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6030616.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11816..12616)
                     /locus_tag="VVR39_001120"
     CDS             complement(11816..12616)
                     /locus_tag="VVR39_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6030617.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12774..13130)
                     /locus_tag="VVR39_001121"
     CDS             complement(12774..13130)
                     /locus_tag="VVR39_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6030618.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13124..13654)
                     /locus_tag="VVR39_001122"
     CDS             complement(13124..13654)
                     /locus_tag="VVR39_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU6030619.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13654..14148)
                     /locus_tag="VVR39_001123"
     CDS             complement(13654..14148)
                     /locus_tag="VVR39_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030620.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14283..14729
                     /locus_tag="VVR39_001124"
     CDS             14283..14729
                     /locus_tag="VVR39_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU6030621.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14726..15373
                     /locus_tag="VVR39_001125"
     CDS             14726..15373
                     /locus_tag="VVR39_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU6030622.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLVIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(15394..15975)
                     /gene="pdxT"
                     /locus_tag="VVR39_001126"
     CDS             complement(15394..15975)
                     /gene="pdxT"
                     /locus_tag="VVR39_001126"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU6030623.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(15976..16851)
                     /gene="pdxS"
                     /locus_tag="VVR39_001127"
     CDS             complement(15976..16851)
                     /gene="pdxS"
                     /locus_tag="VVR39_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU6030624.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17003..18382)
                     /locus_tag="VVR39_001128"
     CDS             complement(17003..18382)
                     /locus_tag="VVR39_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU6030625.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            18676..19599
                     /locus_tag="VVR39_001129"
     CDS             18676..19599
                     /locus_tag="VVR39_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU6030626.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19659..20264
                     /locus_tag="VVR39_001130"
     CDS             19659..20264
                     /locus_tag="VVR39_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6030627.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAKIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20283..21527
                     /locus_tag="VVR39_001131"
     CDS             20283..21527
                     /locus_tag="VVR39_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6030628.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLMGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(21644..21901)
                     /locus_tag="VVR39_001132"
     CDS             complement(21644..21901)
                     /locus_tag="VVR39_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU6030629.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(21943..23979)
                     /locus_tag="VVR39_001133"
     CDS             complement(21943..23979)
                     /locus_tag="VVR39_001133"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU6030630.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHDVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKADLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24239..25156)
                     /gene="glyQ"
                     /locus_tag="VVR39_001134"
     CDS             complement(24239..25156)
                     /gene="glyQ"
                     /locus_tag="VVR39_001134"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU6030631.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(25524..26285)
                     /locus_tag="VVR39_001135"
     CDS             complement(25524..26285)
                     /locus_tag="VVR39_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6030632.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26558..27400)
                     /locus_tag="VVR39_001136"
     CDS             complement(26558..27400)
                     /locus_tag="VVR39_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU6030633.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27514..28905)
                     /locus_tag="VVR39_001137"
     CDS             complement(27514..28905)
                     /locus_tag="VVR39_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU6030634.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29140..29517)
                     /locus_tag="VVR39_001138"
     CDS             complement(29140..29517)
                     /locus_tag="VVR39_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6030635.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            29750..30727
                     /locus_tag="VVR39_001139"
     CDS             29750..30727
                     /locus_tag="VVR39_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6030636.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSEEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGLLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            30724..31806
                     /locus_tag="VVR39_001140"
     CDS             30724..31806
                     /locus_tag="VVR39_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6030637.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT         9453 a         7181 c         5733 g         9576 t
ORIGIN      
        1 tattagaaag ttggctctct aattaaatta attctcatta tatatatcaa aagaccgcag
       61 cttgaaaact acggtctaat tttttgtcca aatgtaaacc acttggaact attattcaat
      121 ttattctttt tagtaaatgt tcccgtttta atcccagtta cagtttttaa tcctctgtaa
      181 ccgttgattt tacaaagctt ttaatttttt tgcgattatt cccactcaac tgttgcaggt
      241 ggtttacttg taatatcgta gacgatacgg ttaacatgat ccacttcatt tacgatacgt
      301 actgagattt tttgaagtac ttcccatgga attttggcaa aatcagcagt cataccatcg
      361 atagaagtga tagcacggat tgcaatcgtg tagtcatacg tacgaccgtc acccataaca
      421 ccgactgaac gaacgcctgt gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca
      481 gctttagcga tttcttcacg aagaatagcg tctgattcac gaacggtttc aagtttctct
      541 tcagtgattt cacccatgac acggatagca agtcctggtc ctgggaatgg ttggcgccat
      601 acgatatggt ctggcatacc aagctctgta ccaagagcac gaacttcatc cttgtaaaga
      661 gtattgagtg gttcaatcaa ttcaaactgc atatcttctg gaagaccacc cacgttgtgg
      721 tgtgacttga tagtttgagc tgtatccgta ccagactcga taacatctgt atataaagta
      781 ccttgagcaa ggaatttcac atctttgagc ttgcttgctt cgtcatcgaa tacatagaca
      841 aactcgttac cgatgatttt acgtttttgt tcagggtcag aaacgccagc aagtttgtca
      901 aggaaacgtt tagcagcgtc tgctttgacg atattcaaac caaacttacc accgagcatg
      961 tccataactt gatcagcttc gcctttacga agaagaccgt ggtctacgaa gatacagatc
     1021 aattgatcgc caatcgcttt ttggagaaga accccaacga cagatgagtc aacaccacct
     1081 gatagaccaa gaaggacacg tttatcaccg acggtttcac gaattttttt gatctgcatg
     1141 tcaatgaaat tatccattga ccagtcacct ttagccttac aaatgttaag ggcaaagtta
     1201 cgaaggatat catttccgta tacagaatga cgaacttctg ggtggaattg gataccgtaa
     1261 atgtgtttat ctgggttttc gatggctgcg tatgggcagt cagctgatgt acctgtacga
     1321 acaaagtcag caggaatctc agtaaccgca tcaccatggc tcatcaaaac agtctgttca
     1381 tcaggtgttg attcaaaaag cgctgatggt gtgtgtgtta gggttgattg accgtattca
     1441 cgatttccag catcacctgc aggaacaact tttcctccaa gtttatgggt caataactgc
     1501 ataccataac agattcccaa aattggaatt ccgagttcga agatttctgg gtcaatatca
     1561 aatgaaccat cttcatatac agaatttgga ccacctgata gaataattcc tacaggattg
     1621 acttcacgaa cttcagcagc tgaaatttta tggcttttta gttctgaaaa aacaccaatc
     1681 tcacggatac ggcgtgaaat cagctggttg tactggctac catagtccaa tacgatgatt
     1741 ttttctacat cttgcaaatc agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa
     1801 tatcttttcc caatattcta tcacaaataa gggcgaatta ccaactaaac aaggcgaagt
     1861 ttgacttttt ctagtttatt gaggtacaat agagaaaaga tagaaatgaa gtgaaaaata
     1921 tgctacctgc ttatatgaaa atccatgatc agataaaaaa ggatattgac gagtaccgtt
     1981 gggctattgg tgagaggctt cccagtgaaa gagatctagc tgagcagttt gcggtcagtc
     2041 gcatgaccct ccgccaagcc gtatctctat tagtcgaaga aggcgtctta gagcgccgtg
     2101 taggaagcgg cacctttgtt tccagtactc gagtacaaga aaagatgcga gggacaacca
     2161 gttttactga aattgtcaaa tcccaaggta aagttccctc tagccagctc atttcctaca
     2221 aaaaaaccat tcccaatgag caagaagttg ccaagctagg aatttttcca acggacaata
     2281 ttatccgaat ggagcgggtc cgctatgccg accaagttcc cctagtttat gaagttgctt
     2341 ctattcctga aaaattcatt aaggacttta aaaaagaaga aatcaccagt catttcttcc
     2401 aaaccttgca aaaacatggc tatcgtatcg gcaaatctca acagaccatc tatgctcgcc
     2461 ttgctaaaga aaagattgcc cactatttgg aagttgaaaa aggacatgct attcttggat
     2521 tgacccaggt ttcctaccta gaagatggta ctgcttttga atacgtaaaa agtcaatatg
     2581 taggcgaacg ctttgaattt tatcttgaaa ataattagat taccacgcaa aaactctctg
     2641 tcacggacaa agagtctttt ttatttttct aagaataaat ctttcaaaga aatcaaagtt
     2701 acagcaaaca atatcattgc cataccaata aaatcaatgg gataaaattg ttcattcatt
     2761 attaagaagg caaagaaaac cgccgatatt ggctcaattg aagccaacaa gcttgacttg
     2821 accggtccta tcagactggc tcctttaagg aaagctgtat aggcaaagac agtcccgata
     2881 aggataatgc ctgcaaacgc aaggagaaaa tcaagactag tcgggatatc ggcctgtaga
     2941 acccctgtaa aaggaagggc gaccaaacct gctatgacca ttcccacacc aatgaccaag
     3001 ctgctccccc actttttaat caaggctatg ggtaaaatga tatacagagc ataagtcaag
     3061 gcagaaaaga gaccccagaa caggccagca ggtgtcatgg ataactggtc caactgccca
     3121 tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga tggaaactat ctctcccagt
     3181 gtcggtgcca ccctatcctt gatacagcta taaattaaaa ttccgacagg acaaacatac
     3241 tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag cagacagata ggcgaattgg
     3301 ttgagaaaaa gaccaatcag agcaaaaata agaagagaca gcaaactctt tctatccttt
     3361 aaaaagacca gtattttatc ctttgcagta gcataagtca agatcatgag aattccacca
     3421 gcgattaaaa gacgcaagtt ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat
     3481 tggccactcg ttcctgacaa cccccaagca ataccagcca caactgttag taaagtccct
     3541 tttaaactat ttgacatgtc tctccttact cttctttacg aatcaagttc atcacttgat
     3601 tgcggtctaa tatccattga gctctctcgt ccttttcata ggtacgattc gataggaaaa
     3661 tagtggcttc ttgcttctga cgattccaca tgataaaggt acctgtatag cccgtatggt
     3721 ctagccaatc tccttccaaa ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa
     3781 aattttgatt taagtctctt gcaaaatcat ctgctaaata gtgttctaaa aagatttgta
     3841 aatcctttat agtcgaaaat aaaccagcac tcccagcatg tctacccagg agacgagcct
     3901 tgggatcatg cactatgcct gcctctacac ctctaactgt tggaacagca agctcaactg
     3961 gcccaaactt ggtttccgtc attccccaag gtttccagac ttgatccttt aaaatcacat
     4021 ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg
     4081 aataaagaaa ggctggctga cttcgtctgt tgagatgaaa catcgcttcc tttaattcag
     4141 gggctgttaa aagatcacga ttaggaataa aaggatcaag gtctgttgca tgagtcaaga
     4201 gctggcgaat agtgatgtct ggataatcac tctcaggtaa aaaatctatt accagtctat
     4261 caatatctaa ttgacctatt tcccacaaga aggtacaaac tgtgccaacc ccaacaacct
     4321 tgctgacact agctaggtca taaactagtc ctgcctcagt ctgcaagcca tgctctgggt
     4381 cactctggcc taaatagaac tctgtccatt gattgtcctt aaaatacgca aaagaggctc
     4441 cgggataaat tcctgcctcg atttgttctt ctattttttt aataatcttg gtccacttca
     4501 tacttcttca aaccacaatt caacattatt tctatcttta caaaggaaga atttttcaga
     4561 cttaggaata aaatattcag tagactcaaa cttctggcga agacttgcta tgtctaattc
     4621 attgaccaag aacttgagca tagataagtc ccaggtaacc gtattgtcca cagtcaaatc
     4681 ctgcccctga gctggaataa aatcaaggga tgccccaatt tcagatgatt ccaagaaact
     4741 ttcgatatca gttgggagat gtaattccat agaaatctca aatttactta aagaaattga
     4801 tgccaaatct gtttgaaatt caggcttttc tcctacttct actagacttg ctctgtcatc
     4861 ttccgcatga atcaaaatca aatcatcttc tggtgagaaa atttcaaaag cgtagccatt
     4921 ttgaccttta tataatcgat gaatcgaatc tgttttagat aagattcctt caatttctaa
     4981 gggattttcc accttgacaa tcaatctagc tagttttttt cttccctcta ccttacgagt
     5041 acgcatactg ggagcttctt ctaaaaccag cttttcaaga cccgtttggt cacctagtga
     5101 cagaaaggcc gattcttcta acaaggcctt cattccaagg gtttcaatat aaaatgtttc
     5161 atttaatttt ctattattag cttttaaagt aggaataatc cgtacaatct gatttacatt
     5221 cataaattcc tccgtcactt tttattttaa aggattttag aattttttac aagatattat
     5281 gctcaaattt aacattattt agctatttag taaagatagt ctttcaaggc ttttgacaaa
     5341 gcctgataac cagcaatact gaggtgcagt ccatcagttg tatattcttt tttgagttgg
     5401 cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt ccacctgcat ataggcagat
     5461 gcaagctctt gataggcttg attccagttc tgaatttttt cattcgagcg gatatagact
     5521 gcctgctggt acttctctcc ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc
     5581 aatggataat cgcgagcaac ggattgaatg atagcttcga gattattgag agcctcattc
     5641 acaggaacat cctttccgat atcatttgtc ccaatcagaa gaaaaatttt atctactgct
     5701 ccaccatata gatgagcatc aaggttctct agtaacagtc ctgtctgata gccacgaatt
     5761 cctcgattga caatcgtctt tgaagtccca aatagctcct gtagaggata atactcgaca
     5821 atggaatccc caataaaaag aatgtttggt tctacaacag aaatgtgatt taggtgacga
     5881 tatttggttt gaattttttc ttgttccttt aggagccaat tttctaataa ctgtactgcc
     5941 acttcattct cctttttcta accagttttc caagacttga taaactcctc cttggctgtt
     6001 ggctggtgct agagcagtcg ccacagcttt ggctttctca tcagcatttt ccatcgcata
     6061 ggcaattcca gccatttcaa gcatttcaac atcattttca ctatcaccaa aagccatgat
     6121 ttcttgggat ttcaagtccc agcgcttgag taattcctcc aagccccatg ctttatgaat
     6181 cccagcttgg aggatatcaa tgcaaccata gccactggat acagctcgga cacggccatc
     6241 aaagagagca ttgatttctt ccaaaaccga actcaaacgt tcctcaccaa caaccatgct
     6301 catcttgagc acaccaccaa agaggtcaga tgttaattca tccacaaatt gcatccgttg
     6361 gtagaatttt tcaatcattt ctggagtcat aaaactttca agatctgtaa aaatcgtacc
     6421 ttccttgaca aaatcaccct tcagccccgt tacaacaaac tggtcctgac acgctcgacc
     6481 cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa
     6541 ttcattgttt tcaaaaatac gagcgccatt agcaacaacc agaaccactc gatccaccaa
     6601 gggactcagt agttgtctca tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat
     6661 gcccctttga tccaactgat ctaaaatctt ttccaatcgt gggagatcaa gctgacccct
     6721 agcatccagc aaggtcccat ccatatctgt cgcaattacc ttaatcatca tttactttcc
     6781 tctggattca agctaatacc acttcaatcc cacatgttca ttcatttctt tataggctgt
     6841 atcaattcgt tccttagtcg cttcatctaa ctggtcacga tgactgccac ccctctataa
     6901 aatcttccaa aatataagtt tggtaatgat acaagggata tccttctggt gaaaaggttc
     6961 cctttggtgt tcgattgacc caagtaggat gagctttagc tgttccgata gttgtttttc
     7021 catccttctt cttgatggtg acatccatga gaacaccacg ttcagtccac ttagcattct
     7081 cttcatctcc catagattca attcgttgat tggaaatgaa gttccccatt taatagataa
     7141 tgagtttctt atctccatct ttttcaaccg tttcagatgg ttcaacaacg tgaggatgcc
     7201 ctccaaagat aatatccgct cccaaatcga tcatcttgtg ataaagagct ttttgttctt
     7261 cagttggttc caatcgatac tcaacaccca tctgaagcat gataatggtg atatctgctt
     7321 ccttctctgc ccgttcaatt tcaaccttca tcttatcttc gtttaaatct gaaagataac
     7381 gattatagtc ttcctgagaa atatactgct caattccatt gaaaccatag gaataggcta
     7441 acaatgcaac cttgatacca ttcacttcct taatgaccag cggagcctga tcacgtggtt
     7501 cgtgcgtata aactccgatt ggagtgattc cagctttctc aataatatcg gccgttgaaa
     7561 taactccctc aatttgcgaa tccaaaatat gattatgagc taaatccagc acatgataac
     7621 ctgcctcctt aatagcatcc ataacttcaa caggagcatt aaagagaaga taacccgcta
     7681 aataatgatc cttattaatg gttccttcaa aatcaccaat agctaaatct gctgcttagt
     7741 ccccttgctt gagccaagga gtcacatact caaaattttc atgaaagtca taggtaccgt
     7801 cttctttttt agctgaaaag aaaagtccat cgtggtagag caaatccccg tgggccataa
     7861 ttctggcagt tttttcctct tcctactcct gagacttttg cttagtcccc tcttgagaaa
     7921 tagtatctcg tttttgacta gtcaagggat tccttggaag ctttcaaaca acaagaccaa
     7981 gcccattgat aaaccaactg ctagcaagag tatcgccaca aatcccttat tgctccactt
     8041 gcgataactc ctaaaaagtt taccaagccc ttcataaaac gaaaagctaa accaccctga
     8101 tttcgatttt gtcttctttg tatcttcgtt ctccctactt tcttatgcaa gccttttctt
     8161 tttattatat cacagataag tatttctttc tcaattgaat tgaacttccc atctattttc
     8221 tataaatcct aaatgccata atgctttcaa ttcttgtcat tttgtgatat catgtagagg
     8281 aaatgaacta atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta
     8341 actgcactaa acataatata aggagagaaa atgtctgcaa tagaacgtat tacaaaagct
     8401 gctcacttaa ttgatatgaa cgatattatc cgtgaaggga atcctactct acgcacggtt
     8461 gctgaggaag tcactttccc cctatctgac caggaaatca tcctaggcga aaagatgatg
     8521 caattcctta aacattccca agatcctgtc atggctgaaa aaatgggact ccgcggtggt
     8581 gttggactgg ctgctcccca gttagatatc tcaaaacgca ttatcgctgt tttggtacct
     8641 aatattgttg aagaaggcga aactccacag gaagcctacg atttggaagc cattatgtac
     8701 aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc
     8761 ctgtctgttg accgtaacgt gcctggctat gttgttcgcc atgcccgcgt tactgttgac
     8821 tactttgaca aagatggaga aaaacaccgt atcaaactca aaggctacaa ctccattgtt
     8881 gttcagcatg aaattgacca cattaacggt atcatgtttt acgatcgcat caatgaaaaa
     8941 gacccatttg cagttaaaga tggtttactg attcttgaat aaagaaaatc ccgttgcaag
     9001 acggggtttt gtgttataat agaggcatga aaacaaatga tattgtctat ggtgtccacg
     9061 ccgttaccga agccctcctt gcaaatacag gaaacaaact ctacctccaa gaagatctcc
     9121 gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga aaagaaggtg tccatttctt
     9181 ggacatcaaa aaaatctctc tctgagatga ctgaaggtgc tgttcatcaa ggttttgttc
     9241 tacgagtgtc tgaatttgcc tatagcgagc tagattacat ccttgcaaaa acacgccaag
     9301 aagaaaatcc acttctattg attctagatg gtctaaccga tccccataat ctgggttcta
     9361 tcttgcgaac agccgatgcg accaatgttt caggtgtcat cattcccaag caccgtactg
     9421 tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc tattgaacac gttccaattg
     9481 cccgagtgac caacctcagt caaaccttag ataaacttaa ggatgaaggt ttctggacct
     9541 ttggaacgga tatgaacggt actccttgcc acaagtggaa tacaaaaggg aaaatcgccc
     9601 tcatcattgg aaatgaagga aaaggtatct ctagcaacat caaaaaacaa gtcgatgaga
     9661 tgattaccat tccgatgaat ggacatgttc aaagccttaa tgccagtgtt gctgcggcca
     9721 ttctcatgta cgaagttttc cgaaatagac tataaaaaag tttccagtca tctgattgga
     9781 aactttttta tgattaacta tgttctgtaa tgaatttata ggcttcttga ccagcgatag
     9841 ctccatctcc aaccgctgtt gttacttggc gaaggtcttt caagcgaaca tctccaactg
     9901 caaagatacc gtcgactgca gttttcatgt ggttatctgt cacaatccat cctgcctgat
     9961 cttggatatt caattcttta acaaaatcgc taagagggtc caaaccaaca tagataaaga
    10021 caccaccgaa ggcttgttct gtcacttgac ctgttttcac attttcaaat acgactgatt
    10081 ctactcggtt ttcacccttg atttccctta ctacagaatc ccagataaag ctgatttttt
    10141 cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg aagttggtca cgacggtgaa
    10201 caatggtaac agtcttagca aaacgagtca agaagagggc ttcttcaaca gctgaatctc
    10261 caccaccaac taccaataaa tcttggtcac ggaagaaagc accatcacac acagcacagt
    10321 aagaaacacc acgactgttc agttcttctt ctccaggcac tcccaaagga cggtgtttag
    10381 aaccagttgc tacgataact gtacgtgttt catatgtttg gtcatcagtc atcactttct
    10441 taaaatcacc atggtcttcg acattttcaa cataaccata aatgtgctca acaccaagat
    10501 tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc actaatatta gcgtatcctg
    10561 ggtaattttc gatatcagat gtattattca tctgaccacc tggcagacca ccttcaatca
    10621 aagctacttt tagattgctt cgagcagcat acaaggccgc agtcatccct gcaggtccag
    10681 caccgataat aatagtatcg tacatataga ttccttcttt cttgttgtaa ctatctttat
    10741 tctaactctt tcttgtcaat cacgcaagga ttatgccttg aaaacaagaa ttaaactcat
    10801 aaccgcaaag gataatactg ggacaaccaa gactccaatc ataatcatat catagagatg
    10861 ggcttggcga gccctggctg tcttatcaac tcccgacatg gctctcagac caatccaaat
    10921 ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa ctctcgaaat ataaagaaaa
    10981 tagttgcagt agcatgattt ctctcatttc tatctttttt aaagagtaaa ctcagctagt
    11041 ccaactaact gagttttcct ttatctatta tatcaaatat aagtccgttt gtaactagcg
    11101 aagaattctt ttgtccgctc ttctttaggg gtgtggataa tctcatccgg agttccagac
    11161 tcgatgattt tccccttatc taagaagaga atcttatccg caacttgggc tacaaaggac
    11221 atgtcatgac tgaccaaaat catggtctga cctgacttag cagcatctgc aatagacttt
    11281 tctacttcac cgaccaattc tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca
    11341 tctggtttca tagcaagcgc acgcgctagg gcaacccgtt gcttctgtcc acctgataaa
    11401 tggcgaggat aatggttttc acggtccgaa agcccaacct tagccaactc ttccttggca
    11461 atcttagtcg cttcttggtc agataatttc ttgacaacaa ccaagccttc tttcacatta
    11521 tcaagtgctg ttcggcgttc aaataaatta aactgttgga aaaccataga caacttacgg
    11581 cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat caactgaaaa accatcaatc
    11641 tgaatagagc cactgtcagg tgtttcaaga taattgagac tgcgaagaaa ggttgatttt
    11701 ccagctcctg aagaaccaat caaggctaca acttcccctt tttgaatatc caagtccaga
    11761 tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac
    11821 gaaggtctcc tttcacatct gtttgcactg tatcaggtgc agaaatagcc atttttctct
    11881 cgatgaaacg accgaggctt tcaattccga tattgactac ccaataaaca agggcaacgg
    11941 agatgaagcg ttcaaaatag cgataatcag ctccacctag aatctgagct tgggcaaaga
    12001 cttccacaac acccgcacta aaagctagag atgttccctt ggtcaaaccg atgagggaat
    12061 taatcaaggt tggagtagct accaccgctg cattaggaat aatcactcgt cgataaactt
    12121 gcgctcgggt catacccaga ctgcgtgccg cctcaatctc accaggatta actgagagaa
    12181 tggctgcacg aatggtttca ctagcataag ctgcctcatt aaaggcaaag gcgacaatcg
    12241 caaaagctgc agctggaatc gcattgatat tgagaccagt tccccattgc tgattgaggg
    12301 ctttcaaagc caaagggatt ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc
    12361 cttttaagaa actaacaaag aaggcctgca agggatataa aatcttgaca cgattgatct
    12421 tcacaatggc aaaaagaagc gccaaaacca agccaaaaag ggcaccacca attgtcaaca
    12481 taattgttgt tggaagttgt tggacaattc tagggattcc atcaaagacc gaacgtaggc
    12541 taaacagctt gccatccgga atcaattgca tcaagttttg gtaccaatct gatgctaaaa
    12601 tcgttgtaac attcataaaa acatcctctt ctgataatga ttcattctac catgcttctg
    12661 ccgtcaatga aattatttgc tacggtcaga tacagacttt gtctacctac tagtttatca
    12721 tactttgaaa cagggaagtt atatatttta tctatcaaag agatagataa aaactatttc
    12781 agtcccagtt cttcataaga ttttcgataa ccgatttgct taacggttcc attttctact
    12841 aaaatgggcc gttttaacaa cataccgtca cttgctagca actcagccgc ttcttggttt
    12901 gacaaacttc ctaccttatc ttttagccct aattcacggt atttgatacc actggtgttg
    12961 aaaaattgct tcaattcaaa tcctgaggtt tctagccaat tcaaaatgac ttcttggcta
    13021 ggtgtttctt ccacgatatg gacggcttta tagtccacac ctaattgatt taattcttgt
    13081 tttgcttttt tacaagttga acatttggga tattcgataa attctaacat gtgcttctcc
    13141 ttctattgtt tctatcttta aaatctactc cttcatgctc caagagccaa gctttctttt
    13201 ccactcctgc agcataacct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    13261 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    13321 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat
    13381 agtcccaaac tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat
    13441 cctgaggctt gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    13501 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    13561 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    13621 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    13681 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    13741 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    13801 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    13861 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    13921 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    13981 caaggctacg taggcttgcc ctgagataat atcatcgata ataacatctg catttggata
    14041 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    14101 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    14161 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    14221 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttga
    14281 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    14341 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    14401 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    14461 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    14521 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    14581 cagaccaact ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc
    14641 ctattatcca aaccagctgc caaaccgtta aactctatca tcaaactcta gacttaatcg
    14701 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    14761 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    14821 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    14881 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    14941 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    15001 cgttgccatt gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    15061 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    15121 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    15181 tctggttatc attcctgcca ttatcaatca aacgacaccc gttttctgga gtctcatggt
    15241 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    15301 ccacatgatt tggcatctct ttatcctagc tgcgtccgta ctccaataca tcgctattgt
    15361 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    15421 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    15481 atttttttct tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc
    15541 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    15601 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    15661 catatccata gttcctagat gactctcttt ctgagaagtg atttccttag ccaacaaaat
    15721 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    15781 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    15841 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    15901 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    15961 tattccgatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    16021 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    16081 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    16141 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    16201 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    16261 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    16321 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    16381 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    16441 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    16501 cttatccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    16561 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    16621 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    16681 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    16741 accagcagct tctgcgatac gagcctgttc aggattctgt acatccataa taacaccacc
    16801 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    16861 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    16921 gataaaaaaa ctataattgt atggggacag attggctaaa aactatctga ccttaactta
    16981 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    17041 tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    17101 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    17161 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    17221 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    17281 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    17341 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    17401 cacaagcatt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    17461 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc
    17521 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    17581 tcttaccatc tgcaagggct gtgtttggac gaaaaccaac tgcaaggata accatatcca
    17641 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accgtcacct tcgattgctt
    17701 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    17761 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    17821 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    17881 caacggcgat acggtcgagg tgttggctct tgtcagaaag tttattgata acttcttcag
    17941 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaac tcgcggtttc
    18001 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    18061 tcaatttttc gtatgattct ttgtgctctt ttccttcaac ttccgctgta actactttgt
    18121 tatcatagtc gattgaaaga acaggtgagt tcatgtaaac tttagcacct ttagcttcca
    18181 atttttcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    18241 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    18301 tctcatttcc aaaattatcc aacatggtat taatacatgc tgtaccagcg tggttagcac
    18361 cgactacaac gattttactc ataaaaattt cctgccttca ttctaaattt accttactag
    18421 tataccattt accgttagcg tttacaaggg gggtactatt atttcagcat tttttatcaa
    18481 aaataattcc ccatttatcc tgttttcaag cctcatgaat tttatgagca tatttcttga
    18541 ctttttccaa attttgtttg tgaaaattct aactttatgg tattataata acatgaaaat
    18601 gaaatgtaag ggcttcaatt tagatgatta tttgatatta caacttattt tctataagag
    18661 aaaggagttg gtagcttgac tcttcgttca cattctgaac ggctaatggg gactactatc
    18721 actatttcat tagtggatga gcaagccgat atctttctcc aaaaatcctt tgacttgctc
    18781 aaagaacttg aataccgctt caacgccaat agtcaagaat ctgagttgat ggaaatcaat
    18841 tatcaagcag gaatatcccc cgtcacggtt catccagacc tgtttgagct gatttcactt
    18901 gggttagagc atagcctagc gctctctagc cacctcaata tcagcattgg tcccttaatt
    18961 caaacctggc gtatcggttt ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg
    19021 gtgctgcctc taatcaatcc tcatggtatc gagttagatt cttctacttc tactgtgttt
    19081 ttaaaacaga aaggaatgaa gattgatcta ggttgtttag ccaaaggata cagtgcggat
    19141 aaggttgccc aatttcttag gaaagagggg gtgacttctg ccttgatcaa tctgggaggg
    19201 aatatcctga ccattggaaa aaatcaggca agaggggata acccatggca aatcgggatt
    19261 caagacccag ccaatcctag gggaaatcat ttaatgacca tccctgttgt caataaatct
    19321 gtcgtgactt caggcattta tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac
    19381 atttttgaca gtcaaacagg atatcctgtt gaaacggaac tagcgagtct aacaatcatc
    19441 tctgataaat cagtcgatgg cgaaatctgg acgactcgac tctttggaga aagacctgct
    19501 tctatcctct ggcaagtcga aagtttggag ggtatcgaag tcatcctcat cgataaagaa
    19561 ggccacctaa gctgttcttc aggaattcct actctataga gacaactgtt tcaatggaat
    19621 tttaaaattg tattatgtaa aaagagaaag gaaatctcat gttaaaactt attgctattg
    19681 ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct tcaatacatg caaaaacact
    19741 ttgctgacaa agctaaaatt gaacttgttg aaatcaaggc cattcctgtc ttcaacaaac
    19801 cagctgacaa gcaagtacct gctgaaatat tggaaattgc tgctaaaatc gaagaggcag
    19861 atggcgttat tatcggtact cctgagtatg atcactctat tccagctgtt ttgatgagcg
    19921 ctcttgcttg gttgtcttat ggtatttacc cacttttgaa caaaccaatc atgattacag
    19981 gtgcttctta cggtacgctt ggttcatctc gtgcccaatt gcaacttcgt caaatcttga
    20041 atgctcctga aatcaaggca aatgttcttc cagatgaatt cttgctctca cactctcttc
    20101 aagcatttaa cccaagtggc gacttggttg accttgatgt tatcaagaaa ttggatgcca
    20161 tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa attacgtaat gcacaagaat
    20221 tacttcgcaa agatgctgaa gactttgact gggaaaattt gtaagatagg agaccaaaaa
    20281 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgtaagctct
    20341 tggaatttat ccgtcgctac ttcaaactca aatttgaatt agaagttctt gaaattgacg
    20401 aagttccaat gtttaaccaa gatgaaaaat gggatgaaag tttccaatta cgttatttat
    20461 ataacaaaat tactcgtgca gatggtgtta tcattgctac tcctgagcat aaccacacta
    20521 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    20581 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    20641 ttcaccttcg taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg
    20701 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    20761 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    20821 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    20881 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa
    20941 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    21001 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca
    21061 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    21121 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    21181 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    21241 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    21301 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    21361 actggtacct aaaagagact ggtcaacgtt tgatgggtgg tagcggacca tttgctcctg
    21421 ctgccggagg tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg
    21481 gaggccacgg tggtgacgca gacgctacag ccggtgcaag ttactaatga tagtttttag
    21541 gaaccattat ggttcctttt ttagcgaaaa aagactagca aacacaaact gctagtctct
    21601 ttgttatcgt ttcatctatc tttgttaaaa gaaagagtac atattatgaa tttgggtcat
    21661 caagactacg gccatgtaat cctttttcac gttgtacttg gcgtagtttt tctggtgtaa
    21721 catcgtttcc ttcttcgtcc acaattttga ttccttcaat gtggtgacga acagcgcggc
    21781 gataaccttc gatgtactcc tcacgtagtt tggcttgttc cactttttct tctggtgtta
    21841 agccttctgt ttttttcttt ttagcaagct cattgatacg agcaattttt ttcggatcca
    21901 tttcttctcc tttgtaataa gataaagtcc gtttatcaaa ttttatttag tgttaatttg
    21961 gttaaaacaa gcaaacttag ctgctttctt ggttagttgt gacaagattg ccaaacgatt
    22021 ttgacggaca gcctgatctt cagccattac catagtattt tcaaagaaag catcaatgac
    22081 tgggctaagc gcaaagagtt gtttcaattg ctgacttgca ggtcctgata aaacgagtgt
    22141 ttctactgct tctgccaaag ctttttcttg gtcattctca aatagtgctg aatcaactgt
    22201 agcaacccct tctgccttct cagccaggtt aaaggcacga gaaagtgatt caacagatgg
    22261 tttaaaatct tcttccttgc ttacttctac gagagcactt gctgcttcca acatatctgc
    22321 cacaacaaag tttgaacctg caagaactgc ttccttgata tcttttggag tagagcccat
    22381 catcttatca acacgagcct tgataaagtc cataacctct gctttatttt cataagtcaa
    22441 actgtcaaat ttcaatgcat aaaggctatc aatcagctca tccatagcaa tgtgccaacc
    22501 aaaggcatcc aagatacgaa ccacaccttg agttgcacga cgaagggcat aagggtcatt
    22561 agaacctgat ggaatcaatc ctactgagaa gaaactcaaa atcgtatcca atttgtctgc
    22621 aatggctaga actgcgccga ccttgctctc tggaagttct ccttcagctg atgtaggcat
    22681 gtagtgttca cgaatagcag ctgccaccgc tggagtttca ccagcaagaa gggtgtattt
    22741 ttcacccata attccttgga gttcgtcaaa ttcaccaacc atacctgtca ataagtcaaa
    22801 cttgtaaatg gctgctgcac gagcaaggtc aactgtttca tccactgaca aatcagcttt
    22861 ttctgccaaa agtacagtga tttgacctgt acgaatcatg tgttcacgaa gggaaccaat
    22921 cttctcatgg aaggtgacat tgtttaattt ttcaacaaga tctgaaatca ccaatttttg
    22981 gtcttcacgc cagaagaatt ctccgtcttc caagcgggct accaagactt tttcatttcc
    23041 tttaatgaca tttttcaaac gctctgcgtt tccgttacga acagaaatga agtttggcaa
    23101 gagttttcca tcttgatcac gaacaacaaa gtaacgctgg tgttccttca tagaagtcac
    23161 caagacttct tctggaactt caaggtattt agcatcaaaa cttcccatga aggcagttgg
    23221 gtattcaacc aaattcaaga cttcattcag caaatccgca tcaatttcga tacgtacatc
    23281 atgttttgcc tcaatttcct tgatttggtc aacaatcatt tgctcacgtt cacatggatc
    23341 tgcgattaca aactgcttac gaaggtcttc ttcatagctc aatgctgact gaattttggt
    23401 ttctttcccc aagaaacgat ggccacggct cacacgactt cccttgatat caaggaaatc
    23461 caagtcaaac tcttgctcat ccaagagaac agttaaagtg tgaacagggc ggatgtattc
    23521 aaagctattt cccgcccagt gcatgctgac agggaaagtc aatgacttca atacatccac
    23581 aatgcctgga acaatggctt caactgcttg accaatttct tccttagtga catagacata
    23641 ttcttcaccc ttgatttcac ggaattcgat atcttcaaca gtcaagcctt ttccacggac
    23701 aaatccttga gctgctttgg tgaagtttcc atcactatcc aaggcaattt tctttgctgg
    23761 tcccttgaaa tcttctgtca aatcagactg tttgtctgat aaaccagtca cacgaacagc
    23821 caaacgacgt ggtgttgaga aggtttgaat ggcttcaaaa gacaggcgtt ttcccttgag
    23881 gaaggctgcc attttttcgc ctagttgttt ttcacttggt gtgacaacat aggctggtaa
    23941 ttcttcaaga ccgagttcta ctaataagtt ttttgtcatg ttttttcctt tacattttct
    24001 tcaatctttt ttgatatgca ccttaggtac tggggacgtc gctaactaac tctgtgagtc
    24061 tgtatggaaa tccaatgcta aatttatcaa gatttccaac aatctcatca aagtggattt
    24121 agctgactga tttttgaacc taaggtttca aaaatcccca cctaacagta cggcggtgca
    24181 tatccctcta gcaagtcttc gacttgcctc taacgatttt agagtacagt attactcact
    24241 attctgcgtc ttctgctaaa agtttaactc gtgtttcttc atccaaaagt gggtaaccta
    24301 ggcgtttgcg ttctgcaaca aaggttttgg ctacaacacg ggccaagtta cggatacgag
    24361 cgatatagcc tgcacgctct gttacagata cggcaccacg cgcgtcaagc agattaaagg
    24421 tatgtgaaca tttgagaaca tagtcatagg cagggtgtac caagccttct tctaatgcac
    24481 gaccagcttc tttttcaaac ttatcaaagt tttcaagcaa catttcttgg tccgaaattt
    24541 caaatgaata ttttgagtgc tcatactcag gctggataaa gatttctccg tattttacac
    24601 catcagccca ctcgatatca tagacagagt ctacttcttg aatgtaagaa gccaagcgct
    24661 ccaaaccata ggtaacttcc gcagtcacag ggccagttgc caatccaccg acttgttgga
    24721 aataagtgaa ctgagtgatt tccattccgt caagccaaac ttcccaacca agaccagctg
    24781 aaccagttga tgggttttcc cagttgtcct caacaaaacg aatatcgtgc tccaaaggat
    24841 tgattcccaa tttttccaaa gactcaaggt aaagttcttg gatatttgat ggagaaggct
    24901 tcatgaccac ctggaattgg tggtgttggt agagacggtt agggttttcc ccataacgac
    24961 cgtcagcagg acgacgtgat ggctctacat aagctgcatt ccatggctca ggtccgatag
    25021 cacgaaggaa agtgtaagga ctcattgttc ccgcaccttt ttcattatca taagcctgca
    25081 taagcataca accttggtca ttccaaaatt gttgcaaagt aaggatgatt tcctggaaag
    25141 tcaatttctt agacattgtt tactcctttt tatataaatt acttgcgaca tgaggctgcc
    25201 tcgtcgatca tacgaggcaa gacgagttag tactgcgtct agctcaggca ctctagtgct
    25261 gagcgtgggg cagtccgact gtaaggaggt ttctgccact gatgcagtga aatgttaatt
    25321 tctcagacat tgaatactcc ttaataaaaa ataatttctt gcgacacgag tctgcctcgt
    25381 cgattatacg aggcaagacg agttagtact gcgtctagct cagcacccta gtgctgagcg
    25441 tggagcagtc cgactgtaag gaggtttctg ccactgacgc agtgaaatgt caatttctta
    25501 gacattgttt actcctttag tttttatatt tctttttcaa ttaatttctg ctgaacaaac
    25561 caatctaaca agggaaaagt tttttctgta tttgcccata aatgataaga atctaagacc
    25621 gcttgtacac tacctaaatt ttctaccaac ttatctactg tcaaaaagct gcgccagtat
    25681 tcataaaaaa tacttgcata gttcttatca taagtcgaag aaccaaaatc attcaatgaa
    25741 tgccaaccat acttcttctg aaaaagttct acgagagatt gattacaaat tttttccgct
    25801 tgaaattcct cttctgtcaa gaaatacttg cgactaatat attcaaccat cccctcttcg
    25861 aaccagatat aagagtcata accatcaaaa tcatctaaaa aatgctccga ccaatgagct
    25921 aactcatgtc ctacaatctg taagaggaaa ttttcagata aagaatgata gtgactttct
    25981 attgcttgag tttgctgaga acactcgtag tccatcaatt gatacaaata caactctttc
    26041 caaacagcta aatcaggcgc cataaccatt cgtctattat ttgtataggc tggaacagcg
    26101 ctttccctaa taatctgtgt agcagcatta aaatctgacc aaataacggc ttgcggtaaa
    26161 tcacagactg caagttcatt ctttaaaaaa gattgataat ctttcaactt ttcagtattt
    26221 cttactacaa aatcacgaaa tgtagctagt tgactatcgt cttttacaag ataaaggttg
    26281 tccacggctc tcctttcttt cacacaatag actgaataag caaaagaacc acatctgaca
    26341 atcctaggtt gatttaacct aggggcgtca gaaacgcggt tccaccctaa tttattactt
    26401 cattgttttt gaaaatacta cagaaagcgc cagctcatta ttttgcccta cttggctccc
    26461 actatcccaa gctcgcttga agaacgccat aagactttct ttcttgctga ctattatatc
    26521 aaaaattaga ataatgtaca attcttttta tgattttcta gaaatccaca tcatcaactc
    26581 gtggagcacc cgattgaaca gcaatcgttt ttaaggtttc tctctcctca tgactcagtt
    26641 caattccaaa gcaatcaaga ttagcttgaa tacgagaggt tgtgacagat tttggaagtg
    26701 gtaaaaatcc ttctgccaag ctccaggcca aggctatctg agcaatcgat tttccgtgat
    26761 ttgctgcgat ttcttgcact tgcttgctat caaatagttc tccctgacca aaaggccccc
    26821 aagcttccaa taaaattccc ttttcacgac agtaagctac gacttgatct tgatacacac
    26881 ctggcgccaa gcgaacttga ttgaccgcag gaacgatagt tgcagtttca agcaaggcat
    26941 ccaaatgatg gggaagaaaa ttgctaacgc cgatagcacg gattttccct tcttgataga
    27001 ggtcttccat cgctctccaa acttccgcat tgcgagtttt ccatgcgtca ttttctctga
    27061 gcggttttgg gttcggccaa tgaatcaaat acaaatccaa ataatccaag cccagttttt
    27121 ctatagattt ttccaaagct tgacgagttt gctcataggt ttgctgacta ttccaaagct
    27181 tggtagttac gaacatttct tcacgtggaa ctccgctatc tttgattgct tgaccaacac
    27241 tttcttcatt ctgataaatc gccgccgtat caatatgacg ataaccagcc ttcaaggctt
    27301 ctaacactgc acgataggct tcttctccat ccttagcctt aaaagttcca aatcccaata
    27361 ctggaatttc tactccatta tttaattgat aggtattcat atgcttctcc ttctatttta
    27421 ttcatcaatt atagcataaa acatttttta agtagtacta tcttctgtaa aaaataagtc
    27481 tgtcaaatat ctaacagacc tattttttct tgcttattca tcacgactat agtacagctc
    27541 atgagctttt aggcgagtat tgagcatctc tggtatggtc acaaaggtat aaccttgatt
    27601 tttcaaatac tcaatgaccc ttggcaaggc attgactgtc ggactgtgaa tatcatgcat
    27661 caaaacgata gagccgttag ctacttgatg ctgaatttct gtcaaaatag atgcttcatt
    27721 tttactcttc cagtccagac tatccacatc ccacatgata aagctcaaat ccaagctatt
    27781 gcgaatatca tctgtaatag caccataagg tggacgcatg agtttagaac tagaacccag
    27841 cactttagtt agcacatcct cagtatcagt aatctgcttt ttagcttcat caagagagag
    27901 ttgcgagaga atcggatggc tccaactatg gtttccaaca acatgacctt cagattttat
    27961 cctcttcacc aagtcctcat tcccagaaac atttttccca agcacaaaga aagtcgcttt
    28021 aatatcatat ttagctaggg tctctaatac ctgcggggtc gttgctggat ttggaccatc
    28081 atcaaaggtt agagcgacaa ctttttgata tttcttatca aagtaagatt ggtacaaggc
    28141 cgcatctttt tcgagtaagt acgaagattg gataacatca aagaaagcag atactggcaa
    28201 ggctatctct tctaaatttt caaccacagg acttggataa aggataatct gactatcctt
    28261 gtaatcaaaa ttccatgcag acaagtcttg gtcagagaag ttttttacaa tctgctcact
    28321 ctggtcttgc tctatttttt tatcctctat gaaggaggtc aactctttta tcagctgttc
    28381 cttagcctta ctagcatctg aaaacagttg gtcaagtgta aaaggttgcc catcttctgt
    28441 taagtgaacc tttcctagac tggtcttttc agtctcttca accttaaaag caactaaatc
    28501 atagatttgt ttggtcacat tacgattaac gactcccttt aaacctgact cttcttgctc
    28561 tgtatagtag aaaacaagat tgtccttact ttctagcttg tccttaacat cttgatttat
    28621 caactcccta acagaggaaa tcactttctc cccttggaga ggataatagg caatcacttc
    28681 ggcttgcccc tgacgaaaat gctccttctg atttccctca ctcaattgat catctttctc
    28741 ttttttgagc gattcaatct tttgctcaaa acttttttgc tggtagatct taaaagcaat
    28801 aaatccgcct aataggcaaa tagaaattgc taaaatacca atcaaagcca ataatacatg
    28861 tctcgttttc ccgtgtctgc cacgtcctag tctactttta ttcatattta tatcataaca
    28921 aatttgagca ataatttcaa tgatacaatt tggcaatcca caattcctct agcaagccaa
    28981 agcatcttac atcaactcca acatccgtat ctgtagagat tatgtagttt tctatctatg
    29041 gaatttctag tagattgaag ctagaatagt agacctatac ttctaaaaca ttgttagaaa
    29101 tcgatttgat tgtcctgatc gatttgtcct gttctcattt cattttacta taaaactatg
    29161 aaaagctagg tcatctgaga agtaattact atcgacaatt gcgatagcgt atactggtgc
    29221 gatttgtttg tagctctggt gggtatcacc ttcacgttgg cgaatttttt ctaggttttg
    29281 attaacctga ctgcacagat aagcccatag gcgattgatg aaaaaattct gatgatgaac
    29341 ctgaatttcg atgataactt ggattccatt atctaactcc gccaagacgt ctatactagt
    29401 atagaaatcc tgcgctgagt agggcatgga aggcaagacg tgaatgttac ttccctccaa
    29461 aatcgtcaca ttttttgctg gcaagtccag catatcgcgg ataaattgac aaatcattag
    29521 ttgggctgat acccggatgt ctgagaatcc tccttttcct ccttctatta tagcacattt
    29581 ttaaatctag gtttgctaga ttctatgctt ctatctattt attcggaaaa gaaagctttt
    29641 cttcagaaga aagctaatag cttatttgaa attttctcct ctctgttgga tagtcccgtc
    29701 tatctatgtt ataatgaaag aaggatttaa aatcggaaaa ggagtattta tgctaaaatt
    29761 aggtgtcatc ggaactggcg ctatcagcca tcatttcata gaagcagccc ataccagtga
    29821 agaataccaa ctggtcgcaa tctattctag aaaactagaa actgcagcaa cctttgcttc
    29881 tcgctatcag aatatccaac tattcgatca attagaagtc ttcttcaaat cttcttttga
    29941 tttagtctat atcgccagtc caaactcctt acattttgct caggcaaaag ctgccttgtc
    30001 tgctggtaaa catgttattc tcgaaaagcc agctgtcact caaccacaag aatggtttga
    30061 tttgattcaa acagctgaaa aaaataactg ttttatcttt gaagcagctc gtaattacca
    30121 cgagaaagcc tttactacta tcaaaaactt tttagcagat aagcaagtgt taggagcaga
    30181 tttcaactat gccaaatact cttccaagat gcctgacttg ttgactggac aaacaccaaa
    30241 tgtcttttca aaccgttttg ctggtggagc cctcatggat ttggggattt atcccctcta
    30301 tgctgctgtt cgtctttttg gaaaagccaa tgacgcgact taccatgctc aacagcttga
    30361 taatagcatt gacctaaatg gagatggtct cctcttctac ccagactatc aagttcacat
    30421 caaggctgga aaaaacatca cttccaatct tccttgcgag atttatacaa cagatggaac
    30481 cttgactctc aacacgattg agcatattcg ctcagctatt tttaccgacc accaaggaaa
    30541 tcaagtccag cttcctatcc aacaggctcc tcatacgatg actgaggaag tcgctgcatt
    30601 tgcacacatg atccagcaac cagatctgaa tctctaccaa acttggctgt atgatgcagg
    30661 ctctgttcat gagctactat ataccatgcg ccagactgct ggcattagat ttgaggcaga
    30721 aaaatgaaaa ccaaactacc gactgaatgg caagaactga gtgaccaact cggtttccaa
    30781 gaattcaccc ccattcaaac tcaactattt gagccccttc ttgctggaga aaacctccta
    30841 ggagtgagcc aaaccggaac tggtaagacc ctagcgtatc tcctaccaag tcttctcaga
    30901 ctacaaaaga aaaaagccca acaactcttg attctagcac caaatacgga acttgctgga
    30961 cagatttttg atgtatgtaa aacgtgggca gaagctatcg gattgactgc tcaactcttc
    31021 ctttcaggtt caagtcagaa acgacaaatt gaacgtctta aaaaggggcc agaaattctg
    31081 attggaactc ctggccgtat ctttgaactc attaaactta aaaaaatcaa gatgatgaat
    31141 gtggaaacca tcatcctgga tgaatttgac caattactag atgattctca gattcacttt
    31201 gtagaaaaaa tcactcacta cgcacctcgt gaccaccaac tggtctacat gagtgccacg
    31261 accaagtttg accaagaaaa gattgtaccg aatacacgca ctattgatct ctctgatcaa
    31321 aaattggaca atatccagca tttctacatg caggtagacc aacgtcatcg agtggatatg
    31381 ctacgaaaac tggctcatgt agaggatttc cgtggtctag tcttcttcaa tagcctgtca
    31441 gaccttggga atgccgagga aaaactacag tatcgtgata tattggctgt ttccctcgct
    31501 agtgatgtta atgttaaatt tagaaaaatc atcttagaaa agtttaaaga taaccaacta
    31561 accctgcttc ttgcaactga ccttttggct cgtggaattg atatcgatag cctagaatgt
    31621 gtcgtaaact ttgatattcc tagagatagc gaaacctaca cacaccgtgc tggccgtact
    31681 ggtcgtatgg gcaaagaagg ttatgttatc actctcgtca ctcatccaga agaaatcaaa
    31741 aaacttaaaa agtttgcaag tatccgagaa attgtcctaa aaaaccaaga actctatatc
    31801 aaataaagcc ccattgctct atacacatcc agtgtatgaa gcttttttat aagcaattca
    31861 attttatact catctgcttt caaaaagcat tctagtccat ttccgattaa caatggactt
    31921 tatcacctcc ttctccagtt ctt
//
LOCUS       DAVHSL010000025        31488 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000025 DAVHSL010000000
VERSION     DAVHSL010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.025"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            90..1982
                     /gene="pepO"
                     /locus_tag="VVR39_001141"
     CDS             90..1982
                     /gene="pepO"
                     /locus_tag="VVR39_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU6030638.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHHLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2104..2733)
                     /locus_tag="VVR39_001142"
     CDS             complement(2104..2733)
                     /locus_tag="VVR39_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6030639.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3727..5949
                     /locus_tag="VVR39_001143"
     CDS             3727..5949
                     /locus_tag="VVR39_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU6030640.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVSGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5979..6422
                     /locus_tag="VVR39_001144"
     CDS             5979..6422
                     /locus_tag="VVR39_001144"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU6030641.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6893..7306)
                     /locus_tag="VVR39_001145"
     CDS             complement(6893..7306)
                     /locus_tag="VVR39_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030642.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7437..8084)
                     /locus_tag="VVR39_001146"
     CDS             complement(7437..8084)
                     /locus_tag="VVR39_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU6030643.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(8110..8301)
                     /locus_tag="VVR39_001147"
     CDS             complement(8110..8301)
                     /locus_tag="VVR39_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030644.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGGRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(8282..8932)
                     /locus_tag="VVR39_001148"
     CDS             complement(8282..8932)
                     /locus_tag="VVR39_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU6030645.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQMNMDIAKQLYVEKIN"
     gene            9044..9886
                     /locus_tag="VVR39_001149"
     CDS             9044..9886
                     /locus_tag="VVR39_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6030646.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9962..10399
                     /locus_tag="VVR39_001150"
     CDS             9962..10399
                     /locus_tag="VVR39_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU6030647.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10468..10770
                     /locus_tag="VVR39_001151"
     CDS             10468..10770
                     /locus_tag="VVR39_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030648.1"
                     /translation="MYLVIGIVLAFIVSFWKYNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPNYLSMLFDFY"
     gene            complement(10861..11934)
                     /locus_tag="VVR39_001152"
     CDS             complement(10861..11934)
                     /locus_tag="VVR39_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU6030649.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKLFGQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            12090..12767
                     /locus_tag="VVR39_001153"
     CDS             12090..12767
                     /locus_tag="VVR39_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6030650.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12760..13734
                     /locus_tag="VVR39_001154"
     CDS             12760..13734
                     /locus_tag="VVR39_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6030651.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13783..15726)
                     /gene="thrS"
                     /locus_tag="VVR39_001155"
     CDS             complement(13783..15726)
                     /gene="thrS"
                     /locus_tag="VVR39_001155"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU6030652.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15784..15960)
                     /locus_tag="VVR39_001156"
     CDS             complement(15784..15960)
                     /locus_tag="VVR39_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6030653.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(15967..16107)
                     /locus_tag="VVR39_001157"
     CDS             complement(15967..16107)
                     /locus_tag="VVR39_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6030654.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(16538..16738)
                     /locus_tag="VVR39_001158"
     CDS             complement(16538..16738)
                     /locus_tag="VVR39_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030655.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLEELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            16977..17606
                     /locus_tag="VVR39_001159"
     CDS             16977..17606
                     /locus_tag="VVR39_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6030656.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            17747..18016
                     /gene="rpsO"
                     /locus_tag="VVR39_001160"
     CDS             17747..18016
                     /gene="rpsO"
                     /locus_tag="VVR39_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU6030657.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18830..19444
                     /locus_tag="VVR39_001161"
     CDS             18830..19444
                     /locus_tag="VVR39_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU6030658.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19735..20484)
                     /locus_tag="VVR39_001162"
     CDS             complement(19735..20484)
                     /locus_tag="VVR39_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU6030659.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20617..22953
                     /locus_tag="VVR39_001163"
     CDS             20617..22953
                     /locus_tag="VVR39_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU6030660.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVSLNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DSLLLSGSFLASGSVLARVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23482..24945
                     /locus_tag="VVR39_001164"
     CDS             23482..24945
                     /locus_tag="VVR39_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6030661.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            24938..25366
                     /locus_tag="VVR39_001165"
     CDS             24938..25366
                     /locus_tag="VVR39_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030662.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            25344..25793
                     /locus_tag="VVR39_001166"
     CDS             25344..25793
                     /locus_tag="VVR39_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030663.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            25821..26132
                     /locus_tag="VVR39_001167"
     CDS             25821..26132
                     /locus_tag="VVR39_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6030664.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            26158..27243
                     /locus_tag="VVR39_001168"
     CDS             26158..27243
                     /locus_tag="VVR39_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU6030665.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            27254..27949
                     /locus_tag="VVR39_001169"
     CDS             27254..27949
                     /locus_tag="VVR39_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6030666.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            27986..29956
                     /gene="tkt"
                     /locus_tag="VVR39_001170"
     CDS             27986..29956
                     /gene="tkt"
                     /locus_tag="VVR39_001170"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6030667.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYNDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYIKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            30326..31488
                     /locus_tag="VVR39_001171"
                     /pseudo
     CDS             30326..31488
                     /locus_tag="VVR39_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         9322 a         5743 c         7093 g         9330 t
ORIGIN      
        1 ctaaaaaata atagttaaat ggttattaat tgcattccct agtgattttt gttaagataa
       61 atgcaaatac aaatgaaagc gagaacaaga tgacacgtta tcaagatgat ttttatgatg
      121 ctatcaatgg agaatggcaa cagacagctg aaatcccagc agataagtct caaacaggag
      181 gttttgttga tttagaccag gaaattgaag acctgatgct ggcgacaaca gacaagtggt
      241 tagcaggtga agaagtgcct gaggatgcta tcttggaaaa ctttgtcaaa taccaccacc
      301 tagttcgtga ttttgacaag agagaagctg acggtatcac acctgtctta ccactcctta
      361 aagaattcca agaattggag acttttgcgg attttacagc taaactagca gagtttgagc
      421 ttgcaggaaa accaaacttc cttccttttg gtgtatcgcc agactttatg gatgctagaa
      481 tcaatgttct atgggctagc gctccaagca caatcttgcc agatacgacc tactatgcag
      541 aagaacatcc tcagcgcgaa gagctcttga ctctttggaa agaaagtagc gcaaatctcc
      601 tcaaggctta tgatttctct gatgaagaaa ttgaagactt gctagaaaaa agacttgaat
      661 tggaccgccg agttgcggca gtggtgctct ctaatgaaga aagttcagaa tatgctaaac
      721 tctatcatcc atattcttac gaagatttca agaaattcgc gcctgcccta cctttggatg
      781 acttcttcaa agcagttatt gggcaattac cagacaaggt tattgtagac gaggaacgtt
      841 tctggcaagc agcagagcaa ttttacagtg aggaagcctg gtctctcctt aaagcaacct
      901 tgattttgag tgttgtcaat ctttcaacca gctatttaac agaggatatc cgtgttttgt
      961 ctggtgccta cagccgtgcc ctttctggag ttccagaggc aaaagataag gtcaaagcag
     1021 cttatcatct agcacaggaa cctttcaagc aagccctggg gctttggtac gcccgtgaga
     1081 agttctctcc agaagccaag gcggatgtgg agaaaaaagt ggcaaccatg attgatgtct
     1141 ataaggagcg tctgcttaag aatgactggc tcactccaga aacctgtaaa caggctatcg
     1201 tgaagctcaa tgtgatcaaa ccttatattg gctatccaga agaattgcct gcacgttaca
     1261 aggataaggt agtgaatgaa actgccagtc tttttgagaa tgctctagcc tttgcgcgtg
     1321 tggaaatcaa gcacagttgg agtaagtgga accagcctgt agactataag gaatggggca
     1381 tgcctgctca tatggtcaat gcctactaca atcctcagaa gaacctgatt gtctttccag
     1441 cggccatttt acaggcgcct ttctatgact tgcatcagtc atcttctgct aactacggtg
     1501 gtattggggc agtgattgcc catgaaattt cccacgcctt tgatactaac ggggcttcct
     1561 ttgacgaaaa tggtagcctc aaggattggt ggacagagag cgactatgct gccttcaagg
     1621 agaaaacaca aaaagtcatt gaccaatttg atggacagga ttcttatgga gcaaccatta
     1681 acggtaaatt gactgtatca gaaaacgtgg ctgacttggg aggaatcgca gcagcgcttg
     1741 aagcagctaa gagagaagca gacttctcag cagaagagtt cttctacaac ttcggtcgca
     1801 tctggcgcat gaaaggtcga ccagaattta tgaaactttt ggctagcgtc gatgtgcacg
     1861 caccagccaa actccgtgtc aatgtgcaag taccaaactt cgacgatttc tttacaacct
     1921 atgatgtcaa agaaggagac ggaatgtggc gttcaccaga ggagcgcgtg attatttggt
     1981 aatgcaaaaa atctagttat cagaaaaagg catccaatca cgtgtgaaaa ccttgatagg
     2041 atgccttttg taatagaaag atttgctgga tagtttactt aaatttcgat tgtcatcatc
     2101 ttgctagaaa aagggattga aggccttttc gtgagcgata gtagtagctg gaccatgtcc
     2161 tggatagaca tcgtagtttg gtagggtgaa gagttgggtc tggatactat gaaggagttg
     2221 ctccatgcta ccagtcggaa ggtcggtccg tccgatagtt tcgcggaata gagcatctcc
     2281 cgtcaagact aggtgagcat caggaaagac tagggaaaca ccaccgatag agtgccctgg
     2341 ggtcggtaga accttaaaac gaaattcctc tagttggtat tcttcgtgaa agacaaaggt
     2401 gtgttctgca ggttttgtga ccacatctgc catatcatcg tggcgaggga gaccggagag
     2461 attatcgaca ggagtgtaga gccagctggc ttcgctctct gcgatataga caggaggatt
     2521 gccaaacgtc tcgcgaacca agtccagact catgatatgg tcataatggg cgtgggtcaa
     2581 gagaatagca cagatcggtt tgttgatctt ctcgattgtc tgacgaatgg cttcccaatg
     2641 actaccagga tcgacgacga tgaggtgctt ttcgccttct agataatagg tattttcata
     2701 ggcaacagga ttcacggttt tatggatttt catactagct ccaatctcaa agaatgtact
     2761 aatactcttc gaaaatctct tcaaaccgcg tcaactttat ctgcaacctc aaagcagtgc
     2821 tttgaacagc ctgcggctag ctttctagtt tgctctttga ttttcattga gtataaatta
     2881 agtatagcac agttagggag aataggtaag gatttaaaat gaacttaaaa accagcatga
     2941 ctagatgaag acaggctggt tatcaattta tcaatattgg aaaggtgtca attgcccttc
     3001 ataggttgca taaactccgt cattagcttg tttgatagac gtgatgttta gagtgctacc
     3061 gtagttggct tctcatttgt cgctatattc actataagtt atcctactgg gcaggttctg
     3121 gtcgttagca tagtattgaa cgagtttttt atagctttgc tggctgaata ggaacaggca
     3181 gcaaactcct aacattagga gagcaaagat agaaatagca gtttttttca taggtattct
     3241 ccttataaac taaaggatag aagaaagtat cttgaggatt tttatactct tcaaaaatct
     3301 cttcaaaccg cgtcaacgtc gccttgccgt atatatgtga ctgactttgt cagtcttatc
     3361 tacaacctca aaacagtgtt ttgagcagcc tgcggctagc tttctagttt gctctttgat
     3421 tttcattgag tattaattcc aaaatccagt caaggtacca gtgtatgtga tacgagttcc
     3481 accgtttatc tttcgtatct tcaatggaat tggggaaatc agaaagtctt tgggttacaa
     3541 tatggtttcc gttcttctat ctctccttct atcacctaag tttaaaatct aacttcgtag
     3601 tatattatgg gtcaataatt cagaattatc aagcaatttt gaattatttt tttcttattc
     3661 tgttccaatc tagttttcat attcttaaaa aagtgataaa atggtaggaa gaattggaga
     3721 gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag ttgtcgcttt aaccaaagaa
     3781 tatttaacgg aagaggatgt tcattttgtc cataaggcct tggtctatgc tgttgaatgc
     3841 cacagtggtc aatatcgcaa atcaggcgag ccttatatca ttcaccctat ccaagtgtca
     3901 ggtattttag ctaagctaaa gctggatgct gtaacagtag cttgtggatt cttgcatgat
     3961 gtggtggaag atacagatgc gaccttggac gatttggaaa gagagtttgg tcctgatgtg
     4021 cgggtgattg ttgacggagt taccaagctt ggcaaggtcg agtacaaatc gatcgaggag
     4081 caattagcgg aaaatcatcg caagatgctc atggccatgt ctgaggacat ccgcgttatt
     4141 ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc tgaaacatct tcgaaaagac
     4201 aagcaggagc gtatttccaa agaaaccatg gaaatctatg ccccacttgc ccatcgtttg
     4261 gggatttcca gtgtcaaatg ggaattagaa gacttgtctt tccgttatct caatccaacg
     4321 gagttttaca agattaccca tatgatgaag gaaaagcgca gggagcgtga ggccttggtg
     4381 gatgaggtag tcacaaaatt agaggagtat acgacagaac gtcacttgaa agggaagatt
     4441 tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa tgcaggacaa gagaaaacgg
     4501 tttgaggaaa tctatgatct gattgctatt cgttgtattt tagataccca aagtgatgtt
     4561 tatgccatgc ttggttacgt gcatgaattt tggaaaccga tgccaggtcg cttcaaagac
     4621 tatattgcca accgcaaggc caatggttat cagtctatcc atacgactgt ttatggacca
     4681 aaagggccga ttgaattcca gattcgaacc aaggaaatgc acgaggtggc tgagtacggg
     4741 gttgcggctc actgggctta taagaaaggt ataaaggggc aagttaacag caaggaatca
     4801 gctattggaa tgaactggat caaggagatg atggagctcc aagaccaggc tgatgatgct
     4861 aaggaatttg tggactctgt taaggaaaac tatttggctg aggagattta cgtttttacc
     4921 ccagatggag ctgtccgttc ccttcccaaa gattcaggac cgattgattt tgcctacgaa
     4981 atccatacca aggtcggtga aaaagcaact ggtgccaagg tcaatggccg catggttcca
     5041 ctgacaacca agttaaagac aggggatcag gttgaaatta tcgccaaccc gaactccttt
     5101 ggacctagcc gtgactggct caatatggtc aagactagca aggcgcgcaa taagattcgc
     5161 cagttcttta aaaaccaaga taaggaattg tctgtcaaca agggtcgtga gatgctgatg
     5221 gctcagttcc aagaaaatgg ctatgtggca aataaattta tggacaagcg ccacatggat
     5281 caagttctgc aaaagaccag ttacaagaca gaagactccc tctttgcggc cattggtttt
     5341 ggggaaatcg gtgcgattac cgtctttaac cgtctgactg aaaaggaacg ccgtgaggaa
     5401 gagcgtgcca aggccaaggc tgaggcagag gagcttgtca aaggtggcga ggtcaaggtt
     5461 gaaaataaag aaactctcaa ggtcaagcat gaggggggag tggttattga aggtgcttct
     5521 ggtctcctag tgcggattgc taagtgttgt aaccccgtgc ctggtgacga tattgttggc
     5581 tacattacca agggtcgtgg tgtggctatt caccgtgtgg actgtatgaa cctgcgtgcc
     5641 caagaaaact acgagcaacg tctccttgat gtggaatggg aagaccagta ctctagctca
     5701 aataaggagt atatggccca tatcgatatc tacggtctca accgtacagg actgttgaac
     5761 gatgtactgc aagttctttc aaatacaacc aagaatattt caacggtcaa tgcccaacca
     5821 accaaggata tgaagtttgc taatatccat gtgtccttcg gtattgccaa cctctctaca
     5881 ctgaccacgg ttgtcgataa aattaagagt gtgccagaag tttactctgt caaacggacc
     5941 aacggctagt tgtcctagct cttactagaa aggctattat gaaaatcatt atccaacggg
     6001 ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg aaaaatcaat cagggacttt
     6061 tattgctggt tggtgttgga ccagaggacc aagaggaaga tttggactat gctgtgagaa
     6121 aactggtcaa tatgcggatt ttttcagacg cagaaggcaa gatgaacctg tctgtcaaag
     6181 atattgaagg agaaatcctc tctatttctc agtttaccct ctttgcggat actaagaaag
     6241 gcaatcgtcc agcctttaca ggggcagcta aacctgatat ggcatcagac ttctatgatg
     6301 ctttcaatca aaaattagcg caagaagtgc ccgttcagac aggtatcttt ggagcagata
     6361 tgcaggttga gctggttaat aacggacctg ttaccattat cctagatact aaaaagagat
     6421 aagaaagacc aagcccagtc ggcttggtct ttctcatcga tcataaaata ctccaaaaag
     6481 aaatcggttc ttgatatgct taggggaagt ctcttttcag gctttggcag atgcgatagg
     6541 aagggatgag atgtcctagg atgaggagag ttccctgaag gaaaagtgga atatcactta
     6601 aagacaccaa ggagagaatc atcaggctat cccataggag aatttgtaaa gcaaaacgcc
     6661 agaatctcgg tctaatctgg gaatagagtt aactaaagtg gtcacaaagt tggtttgaaa
     6721 gataggtcaa tagcacagga tgaaagaaaa tgagccaacc gctataaatc aaaatccagt
     6781 cccaagtaag cccccctttt aaatgtcaaa aatgccagca tgattccatc aatgacaagg
     6841 agttgaatgg ttttgatgaa gatgattttt tcatgctaaa acctcctttt ccttagagac
     6901 actcccataa agagatgtgt ttgtcgtaaa agtctggata gttttctctt aggtagtcag
     6961 ctgtcatata ataaaaagta gaatggcaag cagtgataat tgacataaga gatgaaaaac
     7021 gctgagaact aatgaaggct aagagaacaa aaaatagaaa atcaatggtg agaaccccta
     7081 aatagtagaa gcgaatcttt ttattgattt gaggataaat ctcagcgaat tgatgtttga
     7141 gtcggacgac caagagaaat agcaggagtc cttgatcaag gaagaaaatt aaaccagaga
     7201 gcaagagcca ctcaaaagat gtctcgagtc tagtgataaa aaatgcaaat agtagcaaat
     7261 caataactgc aattgctata aaatggattc tatagagttt tttcatgaca agaccttcct
     7321 cttttatcta acttcattct actccaaaag aatgggagtt acaactaaaa tgataaaaat
     7381 agcagagggg agattctctt aagttggcta gtattcttta tttgagtttc cttctattat
     7441 ctaacttctt catcattcca gacaaataaa gctccgattg cattgaggat ataaaagatg
     7501 tatttaccga tattggcgaa gtttccttga ataccagctt ttgtcagctg aacgaaattg
     7561 taaatcaacc aaaagcccca ctgagttgtt agtttcaatg cattcaaagc attggcaatg
     7621 agggacagtg caaaggcaat agttgttacg taggcaagga gattcatctt gcccccatat
     7681 ccgatatagt tggtcacaaa ggcaaagagg aaggcgatga tggaaatgat gatggccgcc
     7741 aattttacct gtttttggct catttggttg ggtctgcctt cttgcgaagc tttccatttc
     7801 tttatagcaa aggtataaat gaggaaggtg acgggatagg taatgatggc cgccttattt
     7861 ccaaggatat aatcaatagc accggacaaa atggtattaa caataccaaa gtaatttccc
     7921 catttgctta atttccccgt gaaacgagtg gacaacatgg aaatcccaac gttggttacg
     7981 gaaatcaatc caaagggtac aagagctgtc catagtcccc agtctacaaa tttatggagg
     8041 cgtgagttga gataaccaga tgcaatcgca atcccaacga ccaaagcaac cccgaagagg
     8101 tcaaactatt tagatgtagc aaaaattttt agtgattttt tcataggtta aactaccttt
     8161 ctttttttca aatattctcc catttttttc aaatattctc ccaccaaatg aaagtaaaat
     8221 aaaatgatag aaataaaacc ctgaaaataa aactttcagg gttggtaggg gacttgagaa
     8281 attagttgat tttctcgaca tagagttgtt ttgcaatgtc catattcatt tgtaaatcct
     8341 cgtcgttact gaggatagtg aaggtattgc tgaagccatc aaactgcttg acttggagct
     8401 ggtcaccgat gtgaagtgag tgcttgtcca gataatggag aatgtcaaaa ctatcgtgca
     8461 cccgagtcag gcggtaggcg ccagcttcct tgatatcagc tagtgggagg ttattgattt
     8521 caacgaggag ttctcccttg gcaggaatag ttcctccgtg ggggcaggtt ttagggaaac
     8581 ctagcagttt atctagtctt tccacgaaca ggtcagagac agtgtgttcc aagacctcag
     8641 cttcctcgtg aatctggtca cttgtatagt ctaaatgatg aactagaaaa acttcaatca
     8701 agcggtgctt acgatagagc tcagagacca gtttgagacc gaggtcagtc agtagatagc
     8761 cacattcctt gtcctttagg atgagatttt cacttttcat tcgtttgatc atttcagtta
     8821 cggcaggggg agagacttgc atgcgagccg caatttcctt gttggtaatc ttatgcaggt
     8881 ctatgccaat ttcataaata cattttagat agtcttcttt gtttggggtc attcgtttcc
     8941 tcttgtctaa tatctttatc tagtatatca aaaaaagcta gatttctcta gctgtgactt
     9001 tttatgttat acttattgca agagaaaaaa cgaggagatg gatatgacga aaatagctct
     9061 tctttcagat attcatggaa ataccaccgc cttggaggct gttttggcag atgctcagca
     9121 gctaggagtg gatgaatact ggcttttggg agatattctc atgccaggga caggacgtag
     9181 aaggattttg gacttgttgg atcaactacc gattacggct agagttttgg gaaactggga
     9241 agacagtctt tggcatggtg tccgtaagga attggacagt actcgcccca gtcaacgcta
     9301 tctcttgcgc cagtgccagt atgttttaga ggaaatttcc ctagaagaaa ttgaagtgct
     9361 ccacaatcaa cctcttcaaa ttcatcgtca gtttggggat ttgacggtgg gaattagcca
     9421 tcatctgcct gataagaact gggggcgaga gttgattcat actggcaaac aagaggagtt
     9481 tgaccgcttg gtgactcatc ctccctgtga tattgctgtt tatggacata ttcaccagca
     9541 gttgcttcgt tacgggactg gtgggcaatt gattgtcaat ccgggttcga ttgggcaacc
     9601 tttctttttg gacgctcagc tacggaagga cttgcgggcc cagtatatga ttttggagtt
     9661 tgatgacaag ggcctggtag atatggactt ccgacgggta gactacgatg tggcagctga
     9721 attgcagctg gctaaagacc tgagacttcc ctattttgag gtttactatg aaagtctggt
     9781 caatgggatc caccatactc atcatcagga atttttgaga gaattggctc agaaagaggg
     9841 ctgcgatcgg gagttagacg actggttgaa aagtggtaac gattgacatt acaactaaaa
     9901 agggtataat aatagaaaaa gaagagtaga ggcagggtag cctcgtaaaa aggagaagag
     9961 gatgcaaatt ccaagtagat ttaccattgc gactcatatg ctgataatca ttgccctcga
    10021 ggggaaggaa agcaaggtga ccagtgattt tctggctgct agtgtcgggg tcaatcctgt
    10081 cattatcaga aagatcttgt cccagttgaa gaaggcagag ctgatttcag tagcgcgtgg
    10141 aacgggcgga acagagattg tcaaggacct taaggatatt agtcttttag atgtttatca
    10201 ggcggtcgaa tgtcttggta agacaggtca actcttcagt ttccatgaca atccgaatcc
    10261 aaattgccct gtaggagctc atattcatga tgttttggat caaaaattgg agagaattca
    10321 gttgactatg gaggcagaac ttggtcaaac cagtctagaa aaagtcgtgg ccgatgcaga
    10381 gagtcagatg aaggattaag agggataaat gccctctttt tttctttgga taattatgat
    10441 aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt attagccttt
    10501 atagtgtcat tttggaagta taatagaagt ttgtggaatc cagtattatt tttattatcc
    10561 ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata cgagaatgtt
    10621 cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt tctaagtggc
    10681 atctttttaa tctataatgg ggtcattttg ttgaaacgag agggacgttc caagcccaat
    10741 tatctttcaa tgctatttga tttttattga ctattagatt ctatttaaaa agacttagaa
    10801 tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt ttcaagagta
    10861 ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa ggcgacccaa
    10921 ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat gaatgtattc
    10981 aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa gaatagtgcc
    11041 aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca cccattcttt
    11101 aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttggc cgaagagctt
    11161 gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg cagtactctg
    11221 aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac cttgtggaat
    11281 gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca attcttgatg
    11341 gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac tttgctcaat
    11401 ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccggcca gaataacctt
    11461 ttgcttagga tgatgagcaa aaaagttctt taaatagcga agggcgtgct tttgagcagg
    11521 aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac tgtcatctgt
    11581 cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag ccgcaaattg
    11641 cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat ttttgaagcg
    11701 cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa gcatggtggg
    11761 ctctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg agaccagatt
    11821 atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat tcaagggaag
    11881 gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg ccataagagc
    11941 tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc atagcctgtt
    12001 tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctagc atggaaaaat
    12061 ctgttataat aatagaaaag gagaagcgca tgcacaagat tttattaata gaagatgatc
    12121 aggtcattcg tcaacagatt gggaaaatgc tctctgaatg gggatttgaa gtggtcctgg
    12181 tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat ctggtcctca
    12241 tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc cgcaagattt
    12301 ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt gtcatggcaa
    12361 tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt cttttagcta
    12421 aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt ttgctggaat
    12481 atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg caagtcttga
    12541 atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca ggcaacatcg
    12601 tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt gatgataata
    12661 ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga ttggtaggat
    12721 ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg gaaacaattt
    12781 tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc tttggcattt
    12841 cttgtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct ctactttttc
    12901 ttcttgtgtt gctttgtaac catattattt ttcacttggg acatattggt ggaaacgcag
    12961 gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt ggaaatagct
    13021 ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc aaaagcagaa
    13081 agaaaactga cggatttgct ggattactat accttgtggg tccatcagat aaagaccccc
    13141 attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa gcagcagcta
    13201 gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta cctgcgttta
    13261 gaaagtttcc atgatgattt gctcttaaag caggttcaaa ttgaggactt ggtcaaggaa
    13321 ataattcgta aatatgctct tttctttatt caaaaaggct taaatgtcaa tctacatgac
    13381 cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga gcaaatcatc
    13441 tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga tgaccaagag
    13501 ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg agtatttgaa
    13561 cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact tggcctttat
    13621 ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc tgaggtcgga
    13681 aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga gtaaaaatag
    13741 atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct caacgcgtga
    13801 tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga cagtttgtgt
    13861 ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt tgtctccaac
    13921 aattaattgg taaggaatct tgctggtttg tgaagcacgg atcttgaact gcattttttc
    13981 attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg ccacttccca
    14041 agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt gtggtgccag
    14101 ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc gttccatagt
    14161 tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag ctccgatgta
    14221 tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa gggtttcttc
    14281 ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg ctgcttcacc
    14341 ttcggcttca aagtagtcca cgcccatttc atcaagagct gcacgaagca tggtttgggc
    14401 attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt cacgaagaga
    14461 gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa tcaactgaag
    14521 ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac cgtcgttgag
    14581 tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt aacggtgcat
    14641 cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat ggtgtttgaa
    14701 aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc cgtcacccat
    14761 gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag tcttgtaaag
    14821 ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca actctttgtt
    14881 tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggtaacc agaatggcaa
    14941 accttgtccc acttcttgtg aaatcataaa gaggtcaagc tctttaccaa gtttacggtg
    15001 gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt tcttgtcaaa
    15061 ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac gccagtacgc
    15121 accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa catgaggtcc
    15181 acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt cgtcttctga
    15241 gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac gtgcctcgtc
    15301 tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt gcatttcttc
    15361 ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag tatcgtagta
    15421 gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa gacgacgagc
    15481 tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat cttcgtgatc
    15541 aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt cgatgagttt
    15601 gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag attgggcaat
    15661 ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga aagtaatgtt
    15721 aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt ttttatcagc
    15781 agactacttc cgagtcctaa cgttcaattg cttttcttta tcagagagga agttttccat
    15841 ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc agatattttc
    15901 tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt gctttgtcat
    15961 caccagtcat tggaaatttc caatatcatt agataaagcc aagaggtctt cttctaccgt
    16021 ccacttgaaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga ttgcccaact
    16081 gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat gcgacatcct
    16141 cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga gagggacacc
    16201 tctgatcggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca agagtagtat
    16261 cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa agggactaag
    16321 tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga ttttgtgaaa
    16381 gttttttgtt tttcattttt tgtagaatat gcttgatgct aataccagaa tccatgccga
    16441 ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca aaggttatga
    16501 tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa cggaaacggt
    16561 agctatagag taacgatata atcaagatta ccagaggtgt aaagaagaga agattgttta
    16621 tatagagttc ctcgagtgta agggggtcag aaacaactag taagaacaac tcataaagtg
    16681 gccaataaaa gaataatatg accagatagt aggggagatg ggaatagaat ctacgcatga
    16741 taatcacctc gttttaaaaa aacagacaac ttagatctct tgctatgatt attatagcat
    16801 gtttaaaaca agaaagtaaa tttgttgaca aagaagattt ttcttttcac tagaatcata
    16861 gttagttttc ttggtagaaa tattttgata ataattaagc aagactattg acattgatta
    16921 ttaagagtgt cacaattatt gtaactaaaa taattacaac aagagaggta taaaaaatga
    16981 aactagcagt tattgcagca aatggacaag cggggaaagc aattgttgaa gaagcagtca
    17041 aacgaggaca tgaagtaacg gctattgttc gttctgaaaa caaaagtcaa gctgagtcta
    17101 ttattaaaaa agatttattt gagttgacaa aagatgatct tactggattt gatgctgtta
    17161 tttcagcgtt tggtgcttat acaccagata cgctaccgct ccacagcaaa tcaatcgaac
    17221 tatttaatca gcttcttgct ggaacacaga cacgttttct agttgtaggg ggagcaggaa
    17281 gtctttatat agatgaaaca aaaacgacac gacttttaga tacgtctgat tttcctgaag
    17341 aatttaagtc actagcaaaa gatcaagcgg atgaattgga tcttcttcgt acaaaaaata
    17401 atctcaactg gacttttgtc agtcctgctg tagattttat tcccgatggt gaaaaaacag
    17461 gaaactacat tctagcagga gaaattttta ctactaatga aaaaggaata agccagatta
    17521 gttatgcaga ttatgctatt ggattggtag atgaacttga aaaaggtcat catataaaag
    17581 aacgtatctc tttacttgaa aaataataac tatgagagta ttaatgtttg acagaaaatt
    17641 taaatcttgg taaaataggg gttgtcgtaa agacaaataa cttcttcttg gttacaggca
    17701 tgccaacctg tcactcggat gaagccaaat aaaaaggaga aacatcatgg caatctcaaa
    17761 agagaaaaaa aatgaaatca ttgcacaata tgcacgtcac gaaggtgata caggttcagt
    17821 agaggttcaa gttgctgtcc ttacttggga aatcaaccac cttaacgaac acatcaaaca
    17881 acacaaaaaa gaccacgcta cttaccgtgg attgatgaaa aaaatcggtc gccgtcgtaa
    17941 cttgcttgca tacttgcgta aaaacgacgt taaccgttac cgtgagttga tcaactctct
    18001 aggacttcgt cgctaattca agatacaaat gctgtcaaaa gcacaaagca aaaataggaa
    18061 aattgacgaa gaaacttcag tttctaggag attttatctt ttttgccaag tgcttaggcc
    18121 gtgttcaatt gagcatatct tgataataaa gctactctaa attgggtagc ttttttgcgt
    18181 tgtcacctta cctcgctata ctcaagtata atcttcggtt acggttccta gcactgtaag
    18241 gtaaaataaa ccagcttttc tcccttcggg gagatttttt tgtttcactg aaagtttcgt
    18301 acgatcttcg cctcgtcgcc tagtctataa acgatttatc tagcaagaat catgatgcta
    18361 agggcgtcaa aaatccgtat gaaaataggg aaatgacaca gtgttcgatg agcacaagga
    18421 gtttcatctt tttcactagg attttagccc gggctaaaat cagctctctg acttcagagg
    18481 gcttttttat tgaggtttta tcggtaacaa ttttggagac tacaaaaacc tcaaatggta
    18541 tcagctaatt acaccataaa ggtgcgcagt tactcggctt ttcaagccga gtagctgtat
    18601 gcaagccccc tagaagagcc cactctttac aaagtaaagt atagtatgtt atactttaca
    18661 tggaagtagt cactgaattc cagttagaaa ttactttgta actacgtttt gaggaggagt
    18721 aaaatgcttt cctacgttcg acattaccca ctagcgatag ctaaattaat gtgtctgtgc
    18781 tctcctgaaa tctgctgatt tattactgac taatacagga ggttttttta tgggacagac
    18841 aatcatatct gctattggtg tttatatttc caccagtatc gattatttaa ttattttaat
    18901 tattttattt gcacagctat cacagaataa acagaaatgg catatttatg cggggcaata
    18961 tctaggcaca ggcttacttg taggggcgag tttagttgct gcttatgtcg ttaatttcgt
    19021 gcctgaagaa tggatggttg gattgcttgg tttaatccct atctatttag ggattcgctt
    19081 tgcaattgtt ggagaagatg cggaagaaga agaggaagaa attattgaaa gattagaaca
    19141 aagcaaggca aatcaactgt tttggacagt tacattgctg acaattgcgt ctggcggaga
    19201 taatttaggt atctatatac cttattttgc ttcgttagat tggtcacaga ccctcgtggc
    19261 cttgcttgtg tttgtaatcg gcataattat cttttgcgag attagtcggg tgttatcctc
    19321 tattccgtta atattcgaga caattgaaaa atacgagcga atcattgtgc ccttagtatt
    19381 cattctactt ggactataca tcatgtatga aaatggcacg atagagactt ttctgatcgt
    19441 gtagattttt ttgtttcact aggattttag ccctctgaaa atcagctctc tgattttcag
    19501 agggcttttt cattgagcat aaatggacaa tcttaaagtt actctattgt agagtggctt
    19561 ttgatttgat taggagattc ttataaatat agtaaaatga aataagaata ggacaaatcg
    19621 atcaggacag tcaaatcgat ttctaaaaat gttttagaag tagaggtgta ctattctagt
    19681 tccaatctac tatataaatg aaaaccttag ctgtttggcc aaggttcatt tcttctatgc
    19741 aagttcttct cttttcttat ctgggttcca gatgaagctt gcgataaagc taaagatgat
    19801 ggttaggata gcgaggataa tagcaaggat gagggcaggg atgcggataa accaccagag
    19861 tggatttggt tttttatcat tgtgccattg tttcgtttct tcgtccagac gttggaattc
    19921 tgtttgaata cgattggcga ctgtttcaat gccttcatca ttcattttct tgatatctga
    19981 gatatcgatt ggatttccaa agttcatatc gacacgttca cggctaatca agcccttcaa
    20041 agtcatggga ccggtgtagg taaccggcat gatacggacc ttggccattt tggcaatcag
    20101 tgctgcgccc cccttgacat cgtttgagtg gcggctacca cttggaaaca tgatgagaga
    20161 gcggtcactt tttttgagaa cgttgatagg atatttgatg gctgaggcgc tgggattttc
    20221 acggtcgatg ggaaaggcgc cacacatacg aatccaccaa ccaaagatac ggttggtaaa
    20281 gagttctttt tttgccataa agatgaactg ttttggcttg gtcgcaaagg ccatataaac
    20341 aggatcccac caggtacggt gaggcgcaac taaaatataa ttttcatctt gattaggaat
    20401 tttatcagta ttatgatagt gagcattgcc attgatggac cataagagca acacaactaa
    20461 tccacgcaaa taagtataaa acatgcgatc tccttcgatt gttttcttgt tattattata
    20521 ccttatcaaa ggagggctgg caaacttttc ccttgactag atgcatattt aggatgaaat
    20581 tagaattctg ttaaaaaaaa tgatataata gaatttatgg ataaaaataa gattatggga
    20641 ttaacccaaa gagaagtcaa ggaaagacag gctgagggtt tggtcaatga ctttaccgca
    20701 tcagccagta ccagcacttg gcaaatcgtt aaacgaaatg tctttaccct ttttaacgct
    20761 ttgaactttg ccattgcttt ggcccttgcc tttgtgcagg cttggagcaa tctggtcttc
    20821 tttgctgtta tctgctttaa cgctttttct gggattgtga ccgagctacg agccaaacac
    20881 atggtggaca agctcaatct catgaccaag gaaaaggtca aaaccatccg tgatggtcag
    20941 gaagtttctc ttaatcctga agaattagtg ctaggagatg tcattcgttt gtctgcagga
    21001 gagcagattc ctagtgatgc cttggttttg gaaggctttg cggaagtcaa tgaagccatg
    21061 ttaacgggag aaagtgattt ggtgcaaaag gaagttgaca gcttactttt gtcaggaagt
    21121 ttcttggcta gtgggtcagt tttagctcgt gtccatcatg taggtgcaga caactatgcc
    21181 gccaaactta tgctggaagc caagaccgtt aaacccatca actcacgtat catgaaatcg
    21241 ctggacaagc tagcaggttt tactgggaag attatcattc cctttggtct ggctctcttg
    21301 ctggaagcct tgcttttaaa aggcctgcct ctcaagtcat ctgttgtaaa ttcgtcgaca
    21361 gcccttttgg gaatgttgcc taagggaatt gcccttttga ccattacttc gctcttgact
    21421 gcagtgatta agcttggctt gaaaaaggtc ttggtgcagg agatgtactc tgttgagacc
    21481 ttggcgcgcg tggatatgct ctgtctggac aagacgggta ccatcaccca aggaaagatg
    21541 caggtggagg ctgttcttcc actgacggaa acttatggtg aagaggctgt tgccagcatc
    21601 ctgaccagct atatggccca tagtgaggat aaaaatccaa cagctcaagc cattcgccag
    21661 agattccaag gtcaagtagt ctatcctatg ctctctaatc ttcccttctc cagcgaccgc
    21721 aagtggggag ccatggagtt agaaggtttg ggaatagttt tcttaggggc acctgagatg
    21781 ttgctggatt ctgaggtccc agaagccaga gaggccttgg agagaggttc acgtgtcttg
    21841 gtcttagctc tcagtcagga gaaattagac catcacaaac cacagaaacc atctgatatt
    21901 caggctctag ccttgctgga aatcttggat cctattcgag agggagcggc agagacgctg
    21961 aactatctcc gttctcagga agtggggctc aagattatct ctggtgacaa tccagttacg
    22021 gtatccagca ttgcccagaa ggctggtttt gcggactatc acagctatgt cgattgttca
    22081 aaaatcacgg atgaggaatt gattgctctg gcggaggaga cagcgatttt cggacgtgtt
    22141 tcccctcatc aaaagaaact cattatccaa acgctgaaaa aagcgggtca tacaacagct
    22201 atgactgggg atggagttaa tgatatcctg gctcttcgtg aggcggattg ttctatcgta
    22261 atggcggagg gagacccggc aacccgtcag attgccaacc tggttctctt gaactcagac
    22321 tttaatgatg ttcctgagat tctttttgaa ggtcgtcgtg tggtcaataa cattgcccac
    22381 atcgctccga ttttcttgat aaagaccatc tactcattct tgctcgcagt tatctgtatt
    22441 gccagtgctt tactaggtcg gtcagagtgg attttgattt tccccttcat tccgatccag
    22501 attaccatga ttgaccagtt tgtggaaggt ttcccaccat ttgttctgac ttttgagcga
    22561 aatatcaaac ctgttgagcc aaatttcctc agaaaatcca tgcttcgtgc cctaccaagt
    22621 gccctcatgg tcgtgtttag cgttcttttt gtgaaaatct ttggaacgag tcaaggttgg
    22681 tctgagttag aaatctcaac tctcctctat tatctcttgg ggtcaattgg tttcttatcc
    22741 gtatttagag cctgcatgcc attcactcta tggcgagtcc tcttgattgt ctggtcagta
    22801 ggaggcttcc tagccacagc tctcttccca agaatccaaa aactgcttga aattgcaacc
    22861 ttgacagaac aaacgttgcc tgtttatggt gtcatgatgt tggtctttac agtgattttc
    22921 atcctgacta gtcgctatca agctagaaaa taaagaaaga ctgcaatctg tggattgcag
    22981 ttttttatac gatggatcta tcgtagatct gatgtgcaag gcctacgtgt ctattatcta
    23041 tcggtgaacc caagagtgat tctcaagcct gcttggattg aggtaataga ttcaaatatc
    23101 tgtagttaga ctatttgaag tttgatgtaa gaaagagaaa gcgacagatt gaagtaattt
    23161 taactctctt ctattgctag aacaaatggt cggataggtt ggtagtttga aaatgaagat
    23221 gcaatctatt gttaaatgga acatagtgtt atttattaga aaatcgtttg gtttatttat
    23281 tatcaaatac gaaaagcaac ttaaatattt caactaaaat agatgttatg aagaaaaggt
    23341 aaaatgattt tggtatagtg aggttctgtt ctatttgata tcatattttt gataaaaaca
    23401 aaaatgtcca ttgcaaagga caaaatgcga agtatattat tttttgaaag cgatataatg
    23461 gaatcataaa ggaggtgtat cgtgtctaga aaacaagaac aaatggaaac gttgttgctc
    23521 cttttgcgag atagtaagga ttatatatct gctaaagtat tgggagaaaa attaaattgc
    23581 tctgataaaa cggtttatcg ccttgtcaag gtaatcaaca aagattgtcc ggtagaagca
    23641 ttcattttat ctgaaaaagg cagaggtttc aaattgaatc caagaagttc cctcgtggac
    23701 gttgatggga attttacaga ggcttttgat cctgaagtaa ggcgtgaaaa attactagaa
    23761 cgtctcttgt tgactgctcc taagccacat tctatttatg atttaggaga ggaattctac
    23821 gtaagcgagt cagtagtact aaaagatcgt cagatattac aagagagtct agcaatttat
    23881 gggttagatt taaaaatgag acaacgaaag ctttttattg atggggatga ggctcaaatt
    23941 cgttcagcca ttctaaatct actgccaatg tttaatcagt tggatttaga gcaaattaca
    24001 cagaataagg ttcagcctct tgacggagaa cttgctcact tttgtttggg attactgatt
    24061 acacttgaga gagaattggg ggtaaacatt ccctatccat ataatataaa tattttctct
    24121 cacctgtata tttttatcag taggaatcgt cgtagtacta gtattcatgt tgtagcacct
    24181 tcaaaaccta ctattgttga tgagaaaatt tacagtgtct gtcaaaaaat tattcaagaa
    24241 attgaacaat attttaagat gaaggttgat gcagttgaga ttgactatct ttatcaatac
    24301 gttgtatctt cgagattgca aaaaccattt tcttccggga agcttccttt ttctcagcga
    24361 gttttagatg tcactcatta ctattttagc cgtatgtgta tggacaatag agagattgaa
    24421 acgacagatc ctgactttgt tgacttggcg agtcatatca gtcccttact gaggagatta
    24481 gataatagag tacagattaa gaatagtctt ttatcacaaa ttcttttaac ctatcctaat
    24541 ctagttaaag agttaacaac tatttctaaa gaagtgagtc tagtatttgg ttttgcgtcc
    24601 ttgagtctgg acgagattgg ttttctagtc ttatattttg cacggtttca agaaaagcga
    24661 gcacgtcctc taaaaacagt agtgatgtgt acatcaggtg tcggaacttc agagctttta
    24721 cgagcacgat tagaaaagca atttactgaa ttggatatta ttgatgtagt tgcttatcat
    24781 caattagatg agctgataaa tctatatcca gatttagatt tcattgtgac gacggtagct
    24841 ttgcaggaac cagcaagtgt cccgtttgtc ctagttagtg tttttctaac cgagggtgat
    24901 aaacaacgtc ttcaagcaaa aattcaggag ataaactatg aataatcttt cgcttgtcct
    24961 tatggatata tctgttcaaa atcgtcaaga agcctacaaa gaattagcaa atcaaatcag
    25021 ccttcttgtt tctgaagata cagaaaaaat agaagagctt ctatattacc gtgagagaca
    25081 gggaagtata gaggttgcta aaggtgttct tctaccacat tgtgaaggaa actttcaaca
    25141 tcatgtctta gtgattacta gattaaaatc acctatcaga gaatggtcga aggatatcca
    25201 gtgtgttgac cttattatcg gtttggccat tgcagtatca caggacaagt catgtattaa
    25261 aacattgatg agaagactag cagatgaatc attcataaat caattaaaac agttaacaaa
    25321 agaagaatta cgggagataa tatatggaaa tcaaagatat tcttaatgtg agtctgatcc
    25381 agacggattt acagatgcag agcaaagaag aggtttttga ggcattagct caactattgg
    25441 ttgagacggg ttatgtgtct gatagagacc aatttatcga aggtctgtat cagagagagg
    25501 cagaaggaca gaccggtatt gggaattata ttgctattcc ccatagcaag agttctgctg
    25561 tggagaaggc gggggtagtc atagctataa atcacaatga gattccttgg gagaccattg
    25621 atgggaaagg ggtcaaagta attgtactct ttgcagttgg tgatgataca gaagctgcta
    25681 gggagcattt gaagacctta tcactctttg ctcgaaaact tggtaatgac gaagttgttg
    25741 ccaaattagt tcgggctcag acatctgatg atgtgattgc agctttttgt taataagaaa
    25801 aaattttgga gggtatccgt atgaaaattg ttggtgttgc agcttgtact gtgggaattg
    25861 cccacactta tattgcacag gaaaaattag agaatgccgc aaaggtagct ggacatgtga
    25921 ttcatgttga gactcagggg acaatagggg tagaaaatga attgagtcaa gagcagattg
    25981 atgcagcgga tgtagttatt ttagcagttg atgttaagat ttctggtatg gaacgctttg
    26041 agggtaaaaa gattatcaag gttccaacag aagtggcagt caaatctccc aataaactga
    26101 ttgctaaagc tgttgagatt gttacgaaat aactgaaaat atttaaggag aaaatatatg
    26161 ttgaaacact taaacttaaa aggtcactta ttgacagcca tttcctatat gattccaatt
    26221 gtttgtggtg caggattctt agttgccatt ggtttagcaa tggggggtgg tgttcctgac
    26281 gctcttgtag caggaaaatt cactatctgg gatgctttag caactatggg tggtaaagcc
    26341 cttggtctct tgccagttgt tattgctaca ggtttgtctt actcgattgc tggtaagcca
    26401 gggattgcac caggttttgt tgttggtcta attgccaatt ctgttggttc agggtttatc
    26461 ggtggtatct tgggaggtta tatagctggt ttcttggttc aagcgattat taaaaaggtc
    26521 aaagtaccaa actggattaa aggtttaatg ccaaccttga ttattccttt tgtagcctct
    26581 ttggtaagta gtttgattat gatttatatt attggagcgc ctatcgcagc ctttaccaac
    26641 tggttgacga gcttattaca aagcttggga agtgcttcaa atggtttgat gggggcagtt
    26701 attggagttc tcagtgctgt tgactttggt ggcccactta ataaaacagt ctatgcgttt
    26761 gtgttgactt tacaggctga aggtgtgaaa gaaccattga ctgctttgca attggtgaat
    26821 actgctacac cagttggatt tggattggcc tattttatcg cgaaattact caaaaaaaat
    26881 atctatactc aagaggaaat cgaaacattg aaatcggctg ttcctatggg gattgtcaat
    26941 attgttgaag gtgtaattcc gattgttatg aataacttgg ttccaggtct cattgcaaca
    27001 ggtatcggtg gtgctgttgg tggtgctgtt tctttgacaa tgggtgctga ttctgccgtg
    27061 ccatttggtg gagtgcttat gttaccaacc atgactcgtc cagtagctgg tatttgtgct
    27121 ttgttagcca acattgtagt cacaggactt gtctacgcga ttttgaaaaa accaataaaa
    27181 catacagaac cagttatgac tgttgaagaa gagattgatt tgtcagatat tgaaattttg
    27241 taagagggta acgatgtcaa gaattgaatt ttcaccatct ttgatgacca tggatttgga
    27301 caaattcaaa gagcagatta cttttttgaa tgataaagta gcatcttatc atatcgatat
    27361 tatggatggc cattttgttc ccaatattac cttgtctcct tggttcattc aagaagttca
    27421 aaaaattagt gacacacctt tatcagttca tctgatggtc acagacccaa ccttttgggt
    27481 agatcaagtt ctcgatttac aatgtgagta tatttgtatt catgctgaag ttctgaatgg
    27541 tcttgctttt cgtttgattg ataaaattca tgatgcaggt ctaaaggctg gtgttgtcct
    27601 taatcctgaa acacctgttt ctacaatctt tccctacatt gatttacttg acaaagtaac
    27661 tattatgact gtagatccag gttttgcagg acaacgtttt ttggagtcta ccttgtataa
    27721 aatccaagaa ctccgtcagc ttagagttca gaatggttat cactacatca ttgagatgga
    27781 tggttcttcg agtcgtaaga ctttcaaaca aattgatgtg gcaggaccag atatttatgt
    27841 tataggtcgc agtggattat ttggtttgga tgacgatatt gccaaagcct gggatatctg
    27901 ttctagagat tacgaagaaa tgaccggaaa aacaatgcca atcaaataat ggtttgagaa
    27961 gaaatttatt agttaggagg aatatatgtc actacaatca gttaacgcca ttcgttttct
    28021 tggcgtagat gctattaaca aatctaattc tggtcacccg ggaatcgtca tgggtgctgc
    28081 gccaatggct tatagcctat ttacaaagca ccttagaatt acacctgagc agccaaactg
    28141 gattaaccga gatcgcttta tcttgtctgc gggtcatgga tcaatgctac tgtatgctct
    28201 cttgcattta acagggtata acgatgtatc catggacgag attaaaaatt tccggcaatg
    28261 gggatctaag acacctggtc atcctgaagt gacgcatacg tctggtgtgg atgcgacatc
    28321 tggtccgctt ggtcagggga tttctactgc cgttggtttc gcccaagcag agcgtttttt
    28381 agctgctaag tacaacaaag atggttttcc tatttttgac cattatactt atgttatcgc
    28441 tggagacggt gacttcatgg aaggagtgtc tgcggaggcg gcttcttatg caggtcatca
    28501 agctttagat aagcttatcg tcctctacga ctccaacgat atctgcttgg atggtgagac
    28561 caaagatact ttctctgaaa atgttcgcgc ccgttacgat gcttatggtt ggcatacagt
    28621 tctggtagaa gatggaacag atttagcagc aatttctaca gcaattgaga cggccaagtt
    28681 ttctggtaag ccgagtttga ttgaagtgaa aacggtaatt ggttacggct cacccaataa
    28741 aagtggtaca aatgctgttc atggtgcacc actaggagca gaagaaacag gagcaactcg
    28801 taagtttttg ggatgggatt acgatccatt tgaagtacca gaggaagtat attctgattt
    28861 caagacaaat gtagcggatc gtggtcagga ggcatacgat gcttgggcta gtttggtgtc
    28921 tgattacaag gttgcttatc ccgaagttgc tagtgagatt gacgctattg tagctggaaa
    28981 atcccctgta accattactg aaaaagactt ccctgtctat gagaatggct tctctcaagc
    29041 aactcgtaat tcgtcccaag atgctattaa tacagcagca gcagttttac caaccttctt
    29101 aggtggatcg gcagacttag ctcactccaa catgacctac atcaaggcag atggcttaca
    29161 agataaatat aatccattaa accgcaatat tcagtttggg gtacgtgaat ttgccatggg
    29221 aacaatcctc aatggaatgg ctcttcatgg tggtttacga gtttatggcg gaaccttctt
    29281 tgttttctct gactacatca aagctgctat tcggctatca gccattcagg agttgcctgt
    29341 aacttatgtc tttacccatg attcaattgc cgttggtgaa gatggtccaa ctcatgaacc
    29401 agttgaacat ttggcaggtt tacgctcaat gccaaacttg actgttatcc gtccagcgga
    29461 tgcccgtgaa actcaagcgg cttggcatca tgccttgacc agtaccacca ctccaactgt
    29521 cattgtctta acccgtcaaa acttggtagt tgaagaaggg acagactttg gtaaggtcgc
    29581 taaaggagcc tacgtcgtgt atgatacccc gggatttgat actattatca ttgctacagg
    29641 atctgaggtc aatctagcta tcaaagctgc taaggaattg gttttacaag gtggtaaagt
    29701 acgtgtggta tctatgccct caaccgaact atttgatgct caagatgcta cctacaagga
    29761 agacatttta ccatctaaga ctcgtcgtcg tgtggccatt gaaatggcag cgacccaaag
    29821 ttggtacaag tatgttggtt tggatggcgc ggtcatcggt attgacatct tcggtgcgtc
    29881 tgccccagct cagactgtga ttgataatta tggatttacg gtagagaata tcgttgctca
    29941 agttaagtcc ctatagaaac caattacaat gaagatacag ctgttgtcag actagcagat
    30001 gtagtgatag acactaatca gatgattggt tatttaaaaa ctataatgag aatgtaataa
    30061 tttatctacg aaagttatag tagatagtat acacaataga gtataccctg aaacggttgc
    30121 gaagtacgct aatcactttg ctactgatct agatagtttc tttaatcaat aaacacagca
    30181 tccacagatt gacttaggat attgtaagtt ttttgaaagc tagagagaag gtctctaaaa
    30241 ttaaaaaacg catagtatag gatgttaaaa tgaactgacc ccaaaagtta gacagaaaaa
    30301 atctaacttt ttggggtgtt ttattatgaa attaagttat gatgataaag ttcagatcta
    30361 tgaacttaga aaacaaggat atagcttaga gaagctttca aataaatttg ggataaacaa
    30421 ttctaatatt aggtacatga ttaaattgat tgatcgttac ggaatagagt tcgtcaaaaa
    30481 agggaaaaat cgttactatt ctcctgattt aaaacaagaa atgattaata aagtctgaca
    30541 tgaaggctgg actaaagata gagtttctct tgaatacggc ctcccaagtc gtacgatact
    30601 tcttaactgg ctagcacaat acaggaaaaa cgggtatact attgttgaga aaacaagagg
    30661 gagagtacct aaaatgggac gtaagccaaa aacgagacct gaagagagga cagaattaga
    30721 acatcttcaa gcagaaaatg agtacctgag agcggagaat gccatcctaa aaaagttaag
    30781 agaactccga ttgaaggagg aaaaagagaa agaagaaaga cagaaattgt tcaagaatta
    30841 atgactgagt tttcgttagc tcttcttcta aaagccatta aactagctcg ttcgacctac
    30901 tactatcact tgaaacagct agataaacca gataaggacc aagagcttaa agctgaaatt
    30961 caatccattt ttatcgaaca caagggaaat tatgcttatc gtcggattta tttagaacta
    31021 agaaatcgtg gttatctggt aaatcataaa agagttcaag gcttgatgaa agtactcaat
    31081 ttacaagcta aaatgcgaca gaaacgaaaa taaaggagac gttggtaaga aggcagagaa
    31141 tctcattcaa ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac
    31201 agaatttgcc attccagcaa gtactcaaaa gctttactta tcaccagttt tagatggctt
    31261 taacagcgaa attatcgcct ataatctttc aacttcaccc aacttagaac aagtacaaac
    31321 aatgttggaa caggcattca aagagaagca ctacgagaat acgattctcc atagtgacca
    31381 aggctggcaa taccgacacg attcttatca tcggttccta gagagtaagg gaattcaagc
    31441 atccatgtca cgcaagggaa acagccaaga caacggtatg atggaatc
//
LOCUS       DAVHSL010000026        30674 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000026 DAVHSL010000000
VERSION     DAVHSL010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.026"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            161..814
                     /locus_tag="VVR39_001172"
     CDS             161..814
                     /locus_tag="VVR39_001172"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU6030668.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            824..1288
                     /locus_tag="VVR39_001173"
     CDS             824..1288
                     /locus_tag="VVR39_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6030669.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1301..2569
                     /locus_tag="VVR39_001174"
     CDS             1301..2569
                     /locus_tag="VVR39_001174"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU6030670.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGTLAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2583..2843
                     /locus_tag="VVR39_001175"
     CDS             2583..2843
                     /locus_tag="VVR39_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030671.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2854..4215
                     /gene="pdrM"
                     /locus_tag="VVR39_001176"
     CDS             2854..4215
                     /gene="pdrM"
                     /locus_tag="VVR39_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU6030672.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4369..5337
                     /locus_tag="VVR39_001177"
     CDS             4369..5337
                     /locus_tag="VVR39_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU6030673.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEKIQAQVKEAVEASVKFAEESPFPPLESAFEDIYTD"
     gene            5353..6345
                     /locus_tag="VVR39_001178"
     CDS             5353..6345
                     /locus_tag="VVR39_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU6030674.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6563..7606
                     /locus_tag="VVR39_001179"
     CDS             6563..7606
                     /locus_tag="VVR39_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU6030675.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7670..9355
                     /gene="lpdA"
                     /locus_tag="VVR39_001180"
     CDS             7670..9355
                     /gene="lpdA"
                     /locus_tag="VVR39_001180"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU6030676.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9419..10408
                     /locus_tag="VVR39_001181"
     CDS             9419..10408
                     /locus_tag="VVR39_001181"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU6030677.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10481..11551)
                     /gene="xerS"
                     /locus_tag="VVR39_001182"
     CDS             complement(10481..11551)
                     /gene="xerS"
                     /locus_tag="VVR39_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU6030678.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12137..13687)
                     /locus_tag="VVR39_001183"
     CDS             complement(12137..13687)
                     /locus_tag="VVR39_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEU6030679.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVYELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13703..14482)
                     /locus_tag="VVR39_001184"
     CDS             complement(13703..14482)
                     /locus_tag="VVR39_001184"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU6030680.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRVI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14469..15320)
                     /gene="ylqF"
                     /locus_tag="VVR39_001185"
     CDS             complement(14469..15320)
                     /gene="ylqF"
                     /locus_tag="VVR39_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU6030681.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15540..15716)
                     /locus_tag="VVR39_001186"
     CDS             complement(15540..15716)
                     /locus_tag="VVR39_001186"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6030682.1"
                     /translation="MQAGIPPDNEVSYALIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(15768..21599)
                     /locus_tag="VVR39_001187"
     CDS             complement(15768..21599)
                     /locus_tag="VVR39_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6030683.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQSQLAELPNTGSK
                     NEMQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYKLTSGEKLPLPKDISGYTYIGYIKEENITSESEVSNQKSSVATPIKQQKVDY
                     SVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPALQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAIQPELPEAVVTDKGEPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSSNPSDSTTSVGESNQPEKNRTATKPENSGNTTSENGPTEPSNGNSTE
                     DVSTESNTSNSNGNEEIKQENELDPDKMVEEPEKKLELRNVSDIELYSQTNGTYRQHV
                     SLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENK
                     YVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDERSY
                     IKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANE
                     ATNGTKIKQVHVDGVLAGERGVGGLLAKADQSNIAESSFKGRIVNTYETTDAYNIGGL
                     VGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDQDAHIQNSYAEGDINNVKH
                     FGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGNAITGYHYTGMKVANTFSSKA
                     NRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEINPLTLPTVEPLSTSGKKDSD
                     FSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKDDQ
                     VITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANLAEYNLGNTGLLYTPNQFLYD
                     RDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELYLEDQFSKTKQNLGDSLKKLL
                     SADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHPDF
                     FGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKVFLP
                     NTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNMVLP
                     LLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDY
                     WYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVGNKV
                     VHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRNGLGPEFF
                     AKGLLQAPDQPRDATITINSILKHSKSDSTEGSRLQVLDPTKRFQNAADLQNYVHNMF
                     DLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKELTEAEA
                     RNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGRRI
                     AYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGKYK
                     TWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVLQDA
                     TGTRWSNYNPETDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(21808..22986)
                     /locus_tag="VVR39_001188"
     CDS             complement(21808..22986)
                     /locus_tag="VVR39_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030684.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEL
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYVDNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQNQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLLI
                     "
     gene            complement(23156..26806)
                     /gene="addA"
                     /locus_tag="VVR39_001189"
     CDS             complement(23156..26806)
                     /gene="addA"
                     /locus_tag="VVR39_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU6030685.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFCYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLSYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAQ
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREVIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVAVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(26803..30078)
                     /gene="rexB"
                     /locus_tag="VVR39_001190"
     CDS             complement(26803..30078)
                     /gene="rexB"
                     /locus_tag="VVR39_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU6030686.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(30278..30433)
                     /locus_tag="VVR39_001191"
                     /pseudo
     CDS             complement(30278..30433)
                     /locus_tag="VVR39_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            30586..>30674
                     /locus_tag="VVR39_001192"
     CDS             30586..>30674
                     /locus_tag="VVR39_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6030687.1"
                     /translation="MWYNLLMAYSIDFRKKVLSYCERTGSITEA"
BASE COUNT         8633 a         6142 c         6344 g         9555 t
ORIGIN      
        1 taaaaagtaa ttataaaaaa tagccagtct ttataaactg tattcacgta ttcaaatcgt
       61 atatatagtc gatttattaa atctttagat aaactgtaaa aagtggtttc catagccact
      121 ttttgctata atagaggcag taaaaatgaa ggagttggct atggaacact cgtcttggca
      181 cgctttgatt aaggcgcaat tacctgaggg ttatttcggg aaaatcaatc agtttatgga
      241 gcaggtctat tctcagggga ctatttatcc acccaaggaa aaggtttttc aggctctctt
      301 gacaacactg cttgaagaag ttaaggtggt aattctaggg caagacccct accacggacc
      361 aggtcaagcg cagggcttga gtttttctgt acctgactct atcccagctc caccatcctt
      421 gcaaaatatc ttgaaagaat tgtcagatga tatcggagtt aagaaatctc atgatttgac
      481 agcttgggct gagcaaggag tcttgcttct taatgcttgt ttgactgttc ctgctggaca
      541 ggccaatggt catgctggtc aaatctggga gccttttact gatgctgtga ttcaggtggt
      601 caatcatcta gatagaccag tcgtttttgt actctgggga gcttatgcac gtaagaagaa
      661 ggcattagtt accaatcctc atcacttgat tatcgaatca gcccatccaa gtcctttgtc
      721 ggtttataga ggattttggg gttccaagcc cttttccaag gccaatgcat tcttaaaaga
      781 gacaggacaa gagccaatcg attggcttag ataaggagaa aatatgcctc agttagcgac
      841 gatttgctac attgataatg ggaaagaact gctcatgctc catcgtaata agaaacccaa
      901 tgatgtccat gaagggaaat ggattggtgt gggtggtaag ctagagagag gagagacgcc
      961 ccaggaatgc gcggcgcgtg aaatccttga agaaacaggg ctcaaagcca agccagttct
     1021 aaaaggtgtc atcacttttc ctgaatttac accagattta gactggtaca cctatgtttt
     1081 taaggtgacg gagtttgagg gcgacttgat tgactgcaat gaggggacgc tagaatgggt
     1141 tccctatgac gaggttttga gcaagccgac ttgggaaggt gaccacacct ttgttgagtg
     1201 gcttttagag gataaaccct tcttttcagc taagtttgtt tatgatgggg ataaattgtt
     1261 ggatacccaa gttgatttct atgaataaag gagaaagcag atgctactaa tcaaaaatgg
     1321 tcgtgtaatg gatcctaagt ctggtttgga tcaagtttgt gatgtcttag ttcaagatgg
     1381 gaaaattatc aaaattgcgc ctgagatcac ggaagaagga gcagaaacga ttgatgctac
     1441 tggtcttgtg gttgctcctg gtttggtcga tattcatgtg catttccgtg aacctggtca
     1501 aacacataaa gaagacattc atactggtac cctggcagcc gctgcaggtg gttttactac
     1561 tgtcgtcatg atggctaata ccagtccaac catttcagac gtggagactt tgcaagcagt
     1621 tctccagtca gctgccaaag agaagattaa tgtcaagaca gttgcgacca ttactaaaaa
     1681 ctttaatggt aaaaacttga ctgactttaa ggcgctctta gaagctggtg cggttggttt
     1741 ctctgatgac ggtattccgc ttgagagcag taagattgtc aaggaagcca tggaggaagc
     1801 caaaaaactc aataccttta tcagccttca tgaggaagat ccaggtttga acggtgttct
     1861 tggctttaat gaaaatattg ctagagaaca tttccatatc tgcggtgcta ctggagtggc
     1921 tgagtacgct atgatggcgc gtgatgtcat gattgcctat gcaactaaag cccatgttca
     1981 catccagcat ttgtctaagg aagaaagtgt taaagtagtg gagtttgctc aggggttagg
     2041 tgcagaagtc acagcagaag tagcaccaca gcatttctct aagacagaag cacttctttt
     2101 aacacaaggt agcaatgcta agatgaatcc accgcttcgt ttggaatcag accgtcgtgc
     2161 cgttatcgaa ggtctcaaat caggtgtcat cacagttatt gcgactgacc acgcgcctca
     2221 tcatgtagat gaaaaaaatg ttgaagatat taccaaagcg ccatctggta tgactggctt
     2281 agaaacatcc ctgtctctcg gcttgaccta tttggtagaa gctggtgagt tgagcttgat
     2341 ggaattactt gaaaaaatga catacaaccc agccaagctt tacaacttta aagcaggtta
     2401 cttggctgag aatggtccag cagatatcac tatttttgat gccaaggctg accgccttgt
     2461 ggactcccat tttgcttcca aagcagctaa ttcaccattc atcggtgaaa ccttaaaagg
     2521 gcaggttaaa tataccatct gtaagggaca aatcgtctat caagcttgat aggagttaga
     2581 atatgaatta ttttcgaaaa cgtagggaga gacaagcgaa atctaatagt ggaatttact
     2641 gtcccgcagc taatcgttcc aaaattcaat atgaaactaa agaaaaagct gaccatgcgg
     2701 ttcaatatga taacggaggt ttggttagaa gctattattg tcgtacatgt gcgtgttggc
     2761 atactacttc aaaatctaat aaacctccgc taagtttgaa aaactatggt ctgaaactct
     2821 ttggtttaga taaatcagaa tagaaagaga agtatgtata agacaaagtg tttacgagag
     2881 aagttggtat tatttttaaa aattttcttc ccaatcctga tttaccaatt tgccaattat
     2941 tctgcctctt ttgttgatac tgcaatgaca ggtcaataca acactatgga cttggctggt
     3001 gtatctatgg caaccagtat ctggaatcct ttctttacat ttctaacagg gattgtgtca
     3061 gccttggtgc ctatcattgg tcaccatctt ggtcgaggaa aaaaggaaga agttgcgtct
     3121 gatttttacc aatttattta tttggccttg ggcctatctg tggtcttgct ggggatggta
     3181 cttttcttgg caccaacaat cttgaatcat attgggttag aagcagcagt agcggcagta
     3241 gcggttcgct atctttggtt tttatctatc gggattatcc ccttgttgct ctttagcgtc
     3301 attcgttcct tgctggattc gctgggcttg accaaactgt ccatgtacct catgcttttg
     3361 ttactccctc tcaatagcgg atttaactat ctcttgattt acggtgcctt tggtgttcca
     3421 gaactgggag gggctggtgc tggtttagga acatccttgg cctactgggt cttgcttggg
     3481 atttctgttc tggttttatt taaacaggag aagctcaaag ccttacacct tgagaaacga
     3541 attccactta atatggataa aattaaggaa ggagttcgtt taggtctgcc tattggggga
     3601 actgtcttcg cggaagtggc tgtcttttca gtggttggct tgattatggc taagttttcg
     3661 tccttgatta tagctagtca ccagtcagct atgaactttt caagtcttat gtacgccttt
     3721 cctatgagta tctcatcggc tatggctatt gtcgtttcct atgaagtggg agccaagcga
     3781 tttgatgatg cgaaaaccta tattggtcta ggaagatgga ctgccctcat ttttgcggcc
     3841 ttcaccttaa ccttccttta catttttagg ggaaatgtgg ccagtcttta tggtaacgac
     3901 ccaaaattta tcgatttgac agcgcgtttt ttaacttata gtcttttctt ccagttagca
     3961 gatacctttg cggcgccgct tcagggaatt ttgcgggggt ataaggatac agttattcct
     4021 ttttaccttg gtttgcttgg ttattggggc gtagcaatcc ctgtggctac gctatttgat
     4081 tccctaacag attttggagc ttattcttac tggatcggct tgattattag tttgattgtg
     4141 agcggggcgc tctaccgttg gcgtttaact gtgattatga agagatttga atctttagca
     4201 aaatccaaac gctaaaaagt ttgtgaaaaa atattcttga caagaaaatc ccttgttttc
     4261 acggggtttt cttttttatt ttgtgaaatt tcttttagaa aaactttgac agtatttgcc
     4321 aaaagcggta aaatagtaag gtaagaagaa agttagaaag gcaagaagat gtcaacttta
     4381 gataaaaatc ttttgctaga aatgttccgt aagatggaag aaatccgtcg catggactta
     4441 aaaattgcac aattagtaaa gaaagggaaa gtgccaggaa tgacgcactt ttctgttggt
     4501 gaagaggcag ctaacgtggg ggctatgtta gctctcaatc cagatgatct gattacctca
     4561 aaccaccgtg gacacgggca agctattgct aaagggattg acctcaacgg aatgatggct
     4621 gaaatccttg gtaaatacac tggaacctgt aaagggaaag gtggatctat gcatatcgct
     4681 gaccttgatg ctgggaacct tggtgccaat ggtatcgtag gtggtggtat ggggatcgct
     4741 gtcggtgcag ccctcagtca gcaaatgcaa aataccggta aaatcgttgt ttgcttcttt
     4801 ggagatggtg cgaccaatga aggtgttttc cacgaagcag tgaacatggc ttctatctgg
     4861 aacctgccag tcattttcta ttgcattaac aacggttacg gtatctctgc ggatatcaag
     4921 aaaatgacca atatagaaca tatccatcaa cgtagcgccg cttatggaat tcctggaatg
     4981 ttcatcgaag acggtaacaa tgtcatcgat gtctatgaag gatttcagaa agctgtagac
     5041 catgttcgca gtggcaatgg tccagtcttg attgaaagtg taacttatcg ctggcttggt
     5101 cactcatcat ctgaccctgg taaatatcgt acgcgtgaag aagtggaatt gtggaaacaa
     5161 aaagatccaa tcgaaaacct ccgcaattac cttattgaaa ataacattgc aagtgccgaa
     5221 gaattggaaa aaatccaagc gcaagtaaag gaagcagtag aagcttctgt taaatttgca
     5281 gaggaaagcc cattcccacc gcttgaatca gcctttgaag atatttacac agactaagga
     5341 gaaagagata aaatggaaac aaaaacaatg tccttccgtg acaccattat ccttgctatg
     5401 tctgaggaaa tgcgtcgcga tgaaaatgtg ttcttgatgg gagaagatgt cggtgtcttc
     5461 ggaggagact tcggtacttc tgttggaatg cttgaagaat ttggtccaga acgtgtccgt
     5521 gactgtccga tttctgaagc tgccatctct ggagcagcag caggagcagc catgacagga
     5581 cttcgtccaa tcgtcgatat gaccttcatg gacttctctg ttattgccat ggacaatatc
     5641 gtcaaccaag ctgctaaaac acgttacatg tttggtggta aaggtcaggt tccaatgact
     5701 gttcgttgtg cagctggtaa cggagttggc tctgccgccc agcactcaca atctctagag
     5761 tcttggttta ctcacattcc aggacttaag gttgtggcac ctggaacacc tgcggacatg
     5821 aaaggcctgc ttaagtcttc tatccgtgat aacaacccag ttattatact tgagtacaag
     5881 tcagaattta accaaaaagg ggaagtgcca gttgatccag actacacaat tccacttggg
     5941 gttggtgaaa tcaaacgcca aggaacggat gtaacagttg ttacttatgg aaaaatgctt
     6001 cgccgtgtgg ttcaagctgc tgaagaatta gcagaagaag gaatttcagt tgaaattgtt
     6061 gacccacgta cccttgttcc gcttgataag gatatcatca taaactcagt gaagaagact
     6121 ggtaaggttg ttctggtcaa cgatgcccac aaaacaagtg gctatatcgg tgaaatttca
     6181 gctattattt cagaatcaga agcatttgac tatctagatg caccaattcg ccgttgtgca
     6241 ggagaagatg tgccgatgcc ttatgcacaa aacctagaaa atgcaatgat tccaacagtt
     6301 gaaagtatca aagatgcaat ccgaaaaact tataacaaag aatagagttg cataagataa
     6361 gttatgtaaa taaaataaag ctgacgagaa actttgtatc ttttaggtgc agagctcttc
     6421 gtcattaata tcttagatta gagcacgggc taaaagctcg gaaaaaagat aaatctcctt
     6481 ggcttcatcg aagccatcgt cgatttccta tttttcagtc gcttttgacg ccctttgtat
     6541 cataaataga attggagagg tcatggctga tgacaagcta agagcgactc ctgcagctag
     6601 aaagttagcg gatgatttag ggataaacct ctacgacgtt tctggctcag gtgcaaacgg
     6661 tcgtgtccac aaagaagacg tggaaactta taaagacaca aacgtggttc gcatttcgcc
     6721 acttgcaaaa cgaattgccc tcgaacataa cattgcttgg caggaaatcc aaggaaccgg
     6781 tcatcgtggt aaaatcatga agaaggatgt tttggccctg cttcctgaaa atatcgaaaa
     6841 cgatagcatc aaatctcctg ctcagattga aaaagtggaa gaagtccctg ataacgtaac
     6901 accatatggt gaaatcgagc gtattccaat gacaccaatg cgtaaggtta ttgcccaacg
     6961 catggttgaa tcttacttga ctgcgccaac cttcaccctc aactatgaag ttgatatgac
     7021 tgaaatgttg gctcttcgta agaaggttct tgagccaatc atggaagcaa ctgggaagaa
     7081 gactactgta acagaccttc tttcgcttgc agttgttaag actcttatga aacacccata
     7141 catcaatgct tcattgacag aagatggcaa gactattatc actcacaact atgtcaatct
     7201 tgccatggca gttgggatgg ataatggatt gatgacacct gttgtttaca atgctgagaa
     7261 gatgagtctt tcagaactgg ttgtagcctt taaggatgtt attggccgta ccttggatgg
     7321 taaattggct ccaagtgagt tacaaaattc aacattcaca atcagtaatt tgggaatgtt
     7381 tggtgttcag tcctttggcc cgattattaa ccaacccaac tcagctatcc ttggtgtcag
     7441 ttcgacaatc gagaagccag ttgttgtcaa tggtgaaatt gtgattcgcc caatcatgag
     7501 tttaggatta accattgacc accgtgtcgt agatggtatg gctggtgcta agtttatgaa
     7561 ggacttgaaa gagttgattg aaaccccaat ctcaatgttg atttaagagc aagagtattc
     7621 atttttaaga tatagataaa ggaaggaaga catggcctta gaagtaatta tgccaaaagc
     7681 cggcgtggat atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg gagaatttgt
     7741 aaaagaagga gaaatccttt tggaaatcat gactgataaa gtcagcatgg aattggaagc
     7801 cgaagaagat gggtacttga ttgccattct caaaggagat ggtgaaactg tccctgtaac
     7861 ggaagttatc ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg gagcagcatc
     7921 gccagaagct agccctgtac ctgtagcaag tacctcaaac gatgatggta agagcgatga
     7981 tgcttttgat atcgttgtga ttggtggagg tcctgctggt tatgttgcag ccattaaagc
     8041 tgcccaactc ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg gaacctgctt
     8101 aaaccgtgga tgtattccaa ccaagaccta ccttcataac gctgaaatta ttgaaaatat
     8161 cggtcatgct gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg ttgatatgga
     8221 aaaactttta gaaactaaat ctaaagttgt taatactctt gttggtggtg ttgcaggact
     8281 tcttcgtagc tacggagtta ctgttcataa aggaattggt acaatcacta aagacaagaa
     8341 cgtcttggta aatggttctg aattgcttga aaccaagaaa atcattcttg ctggtggttc
     8401 aaaagtcagc aagatcaacg tccctggtat ggaatcatca cttgtcatga ctagtgatga
     8461 cattcttgaa atgaacgaag tgccagaaag ccttgttatc atcggtggtg gagttgtcgg
     8521 tatcgaactc ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta tcgaaatgat
     8581 ggaccgtata gttccagcta tggatgcgga agtttctaag aaccttcgct tgatccttga
     8641 gcgtaaagga atgaccatct tgactggtac taaactgcaa gaaatcattg aggaaaatgg
     8701 tcaacttcgt atcaaggttg aaggaaaaga cgatatcatc gcaagcaaag ctcttctttc
     8761 aattggtcgt atgccagacc ttgaaggtat tggagaggtt gagtttgaat tggatcgtgg
     8821 ttgtatcaag gtcaacgaat acatggaaac ttcagttcca ggcatttatg caccaggtga
     8881 catcaacggt actaagatgt tggctcacgc agctttccgc atgggtgaag tttccgctga
     8941 aaatgccctt aaaggaaatc atgcagttgc caaattgaat ttgactcctg cagccatcta
     9001 cactctccct gaagtagcag cagtaggttt gacagaagaa caagcccgtg agaaatacga
     9061 tgttgccatc ggtaagttta actttgctgc taacggtcgt gctattgcat ctgacgcagc
     9121 tcaaggtttc gtaaaagtta tcgctgataa gaaatatgga gaaatccttg gtgtacacat
     9181 tattggtcct gcagccgcag aattaataaa cgaagcatca agcatcatcg aaatggaaat
     9241 cactgttgag gaaatgctga agaccatcca cggacaccca acttactctg aagtgatgta
     9301 cgaagcgttt gcagatgttc taggaatggc catccattca cctaagaaaa aataaaacga
     9361 agatagatta gactggaagg ttatttccag tctctatcat ataaagtaaa gggatatcat
     9421 gaaatacatt atcaatcatt caaatgacac tgcttttaat attgccttgg aagaatacgc
     9481 ctttaaacac cttttggatg aggatcaaat cttcctactt tggattaaca agccatctat
     9541 cattgttggt cgtcaccaga acactatcga agaaatcaac cgtgattatg ttcgcgaaaa
     9601 tggtattgag gtagttcgcc gtattagtgg tggtggagct gtttaccacg atttaaataa
     9661 cctcaactac acgatcatct ccaaagaaga tgaaaataag gcatttgact tcaagagctt
     9721 ctcaactccg gttatcaata ccctggctca acttggggtt aaagctgagt tcacaggtcg
     9781 taatgacctt gagattgatg gtaagaagtt ctgtggcaat gcccaagcct atatcaacgg
     9841 ccgcatcatg caccacggtt gcttgctctt tgacgttgat ttgtcagtcc tcgcaaatgc
     9901 ccttaaggtt tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc gtgcccgtgt
     9961 aactaatatt atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc gtgatttact
    10021 cttggaatac atgaaaaaag agtacccaga gatgactgaa tacgtctttt cagaagaaga
    10081 attggccgaa atcaatcaca tcaaggatac taagtttgga acttgggact ggaactatgg
    10141 taaatcacct gaatttaacg tccgtcgtgg aaccaaattc actagtggta aggttgaagt
    10201 ctttgctaac gttactgaat caaaaatcca agacatcaag atttatggtg acttctttgg
    10261 tattgaagac gttgctgcag tagaagatgt ccttcgtggg gtgaaatacg aacgcgaaga
    10321 tgttcttaag gcgctaaaaa ccattgatat cacacgctac ttcgctggta ttagccgtga
    10381 agaaatcgct gaagcggtag ttggataaat caaaaagaag ttggccaact aaccaacttc
    10441 tttttttgat atttatttac ataatttaaa atacgtaaaa tcataaacta tccagagcat
    10501 tcttttgttc atcactaaca atatgggtat agaggtcagt gacttgtgtg ctagcatgtc
    10561 ctagttggtg actgactaaa acttgtgatt tagtcgcatc atagagccta gttgctagtg
    10621 tatggcgcag tttatggggt gttacacgca ctttaaaatc ctctgagtat ttagcaacca
    10681 ttttctcaac gctagaagca tcgatacgat taggaacacc tctgtagaga gttaaaaaaa
    10741 gggctgtatc tgttttttcc gttttatagc gttgattccg aatggccaga taattctcta
    10801 aataaggttt agcaaaagca gcgacattga ctgagtcacg tttgccacct tttcgagtaa
    10861 catcaataac catcattttt agattgagat ctcttagatc tagattaaca gcttcagata
    10921 agcgaacacc agatgccaag agaagggcaa taatggctaa atctcgttct ttatttttgt
    10981 tgaatgatga gagagctcga tttgaaagct gttgtgggtg ctcttgatcg atataagtta
    11041 gaaaaccttc tgtttcatca cctagaaaga gtttttgctt gatattttca gctctggcag
    11101 caagggtttc tttctttttc ttggttgaaa cttttttcat tacattacga tagaaataag
    11161 gttccccctg atcgttttca acctcctcgg ttagatactt gtaaagacta gaaagtgctg
    11221 ataaggttcg attgatagtt gtctgtgaaa caccttgttt tgttgtatta gcattcagca
    11281 agggacgttc acgtagataa aggataaagg attccatgtc tttcttagac atattttcca
    11341 aaactgataa aggaatatcg gatattttat cagcgtttga aataccagac tccaaaaccc
    11401 agctgaaaaa tcggtcatat tccttaaggt attcgtacag ggttgtaaaa ctgtagggca
    11461 cagccagctt agattggtag tattccagaa cataccaggg catgagttgt tttagtttgt
    11521 cgattcgttc cagtaaaatc tcacgtttca tgtattttct ccataagtaa gtatactagt
    11581 agtatagcat agacttgtgt atttttcaag aaaattatag tttttcagaa agatgttata
    11641 ggagtttttc aaagtgataa aaagacttag acctacaaac aaaacagaat aaggaaaata
    11701 atgaaaatct cacccactaa acttctgtta atactacata actgaagagc tatataagga
    11761 gctatgagat acaaaacaca ttgtataata gattgaaact agaatagtac atctggactt
    11821 ctaaaacatt gctagaaatt gatttaattg tcctgtttgt tttatcctat ttctatttca
    11881 tttcactata attactattg ttttcttttt catgatttta atcttactgt acagatttga
    11941 tacagtaaac tcctttctag ctttatgctt tatcatttct aacttaatta attatagtct
    12001 tatttttaat aaagttcaat tatttatatg taaaattcct catcagtaaa aaataaccga
    12061 tctcatttct gagaatcggt tttctaaata aatcaagctg agcatttaca taacataaat
    12121 tatgtaaatg ctcatactac aacaacaaat ctttgacttt tccaatttca ctttttggaa
    12181 taaccaggtg aatcatatca cccagataca ttctggttga gccgttaact gtttggctct
    12241 tgccattatg gacttgagtt gtgatgagga cgttgtgtgg taagttgagt tcataaactt
    12301 gtttcccagc aattttatca gaaactggta tttcgataag tgtaacttct ccttcgctag
    12361 atacttcttc tggaagcatt ttttccagca tggcttcata gactggcgta cctttgagca
    12421 aatccatgat aatataagaa acaagagtga caagaccaag tggcatgagg ttgcgaatat
    12481 ctcctaccat ctcagttacg aggatcatag cggttaaggg agcttttgat atggctccaa
    12541 aatagccact cattcctaga atgacaaata tagggaattg ctcttgactg acaagtccaa
    12601 gattgacaca gatagcacca attaaggcac caagcaaaga accaagagct aaaatgggga
    12661 ggaaaattcc tcctggcagt ccacttccat agctaatcat actccaaata aagcggatca
    12721 aaaagtaagc taataaaact tggaaactaa aattttgttc agttaaagaa aggacaagct
    12781 gatttccgcc accaatgatt tgaggtaaga agattccgac tggtatgata aggataaaag
    12841 ccaagatggg ataataagct ctatccaaat ggattttttg accaatcaag tcataaactc
    12901 ttccaacgtt taatacagct ttctcataga gaaaacctga aaatccaagg aaaattccca
    12961 tgacgagata tatccaatac tgatctaggg tcatgggagg aatgttatct ggcatatcca
    13021 atactggtgt caaaccgaac atgagtagag acacaaagtt tgctacgatg ctggctgcta
    13081 gagttgagac ccagaaaaag cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa
    13141 gtgctgcaat aggagcatta aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca
    13201 aggaacgttc ctctactgga ctggatttga gccacttggc aattccttta ccaccaactg
    13261 ctccaagttg aatgctgggt ccctctcgac ccagcatgag tccactggca atagcaagaa
    13321 tacctagcac atattttttc caaagaatgc cccaccagtt gagggacatg aggcctttca
    13381 gttcggcttc gacttgagga attcctgagc ctttaatatc tttttctgac cgtgttagtt
    13441 tggcactgag ccaacagatg agtatataaa acaaaaccag tacaaaaaga ttgcgcacta
    13501 agtacccttg atcttgataa actccttgta tcaggtggaa gcccttttca attaagaaac
    13561 gaaaggatcc gacgataatt ccaacgatga ggccgacaat gattcctcga ccaacttggg
    13621 atagtatagt gctggatgca aaagcgaatt ctttcttaga acggactatt tccgactgtt
    13681 cctccatggt atttcctttc aattaacttt cttttttacc taaaaccagt gatttaacgg
    13741 gttcaaagct ggttcggtga attggggtaa ctcctagttt tgtgaggcct tccagatgtt
    13801 tagctgtgcc atatcctgca ttagtagcga aatcatagcc agagaactgc tgatcgtatt
    13861 ctttcatcaa ttcatcacgt gttaccttgg ctactataga tgctgctgcg atagagaggg
    13921 agttggcatc tcctttgata atggaggttt gtgaaatggg caagtccagt ttcatggcat
    13981 caatcaaaag gtgctctggt tgagggctga gctgggagat tgcttcttgc atggctagtt
    14041 tggttgcttc atagatgttg acttggtcga tgacctgatt atctatgata ccaattccaa
    14101 tcgacaaggc ttggtcttga acggcttgga aaatctccag atgtttcttt ttaggaattt
    14161 tcttgctgtc gttgagacct ttaatcttac aatttttagg taaaataacg gccgcagcga
    14221 ctacaggacc agcaagagga ccacgaccaa cctcatcaat acctgcaatt aaggtcaatc
    14281 cttgcttata aagttctttt tcataagaaa gcatggattc caagcgcaaa ttttcatcta
    14341 attcagcttg aatgactctt ttacgcttgc tgatttcctt ttgaactcct gagcgattat
    14401 ccttttcaag ctctaaaaaa atagggcttt ctaactcctt gactgtcaca aggagttctt
    14461 tgatttcttt aatcgttgcc atcgaggtct tccaatgtat ctaaggtata gttaccgagt
    14521 ttgccatcac ggacttcctt cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa
    14581 ccgagggcgc gggtcatatc cataataatc acaggcgctt cttcttcaat tttcatttgt
    14641 ttgaagcgtt cagccagctt ttctggataa tgttctttga aataattgat accaaaaatg
    14701 gtaacctcat ccataggaag caactgatcc ttgatagctc cagtcaatgc caacttaagt
    14761 gcaacagttt catcctcaaa cttaggccag agaatccccg gtgtatccaa gatttccaga
    14821 tctttattgg ttttaagcca ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca
    14881 gcaatctttt taccagccaa acggttcatc agagttgatt taccagcgtt tggaatccca
    14941 ataatcatgg tacgcaaggt ttcaatctga atcccacgtt ctttctggcg agcaatctta
    15001 tcagccatga gcttcttggc cgcatctgtt acaactttta cagtcacttg ctctttggag
    15061 ttgatagcta gcgtctggat tccttgtgat tcaaaatact gacgccattc cttggtcatt
    15121 gctggatcag ccaagtcggc cttgtttaaa atcaagagtt ttggtttatc accaacaatc
    15181 ttggtcaaca taggattttg actagataga ggcaagcgtg catctactaa aatcgtcaca
    15241 aaatcaacaa attttaaatt ttcctgcacc tgtcgacgcg ctttagacat gtgaccagga
    15301 aaccattgaa tagtagccat tgcatttttt tcctttcgta gcaagggttt agcaccccta
    15361 ttttatttta ctattgtttg aacatagaga gttttcaaat gaatgatgtc caaacagttc
    15421 ttgttttatg acatagaaat ctactttata ttatatcatg ccttctttat tttgtccgat
    15481 gatagccttt taccctatct tttaccctat atagaaaaaa gccatcaaat gatgactttt
    15541 cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa actaccaaca
    15601 gctaataggc ctaaagctgt aagctcagaa gttgatgaac ctgttgcagg aagagtttcc
    15661 tgctgataaa taagagcata acttacttca ttatcaggag gaattcctgc ttgaatcttg
    15721 gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta ttttttattc
    15781 tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa gattgctctc
    15841 ttcaacttat ggacggcact gtccgtttct ggattataat tactccaacg tgtacctgta
    15901 gcatcctgca aaacagcttc atccattagt ttctgcaatt catccacatt attgatagtc
    15961 tttgtgccat atcttggcca tggttttgtc ggatctttaa aggtcacctg cttcaagttt
    16021 ccaaactgat ccacccgttc ttggtacata gctgtcttaa attctgccca agttttatac
    16081 ttaccatcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg ttctttacca
    16141 taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt ggaaatatat
    16201 ggtaccatac catccttaaa gcctttggca gccaaaagtt cgtacgcaat cctacgtccc
    16261 ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg ggcaaagagt
    16321 ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg agctgataag
    16381 atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc ttctgtcaat
    16441 tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt cacatacttg
    16501 ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt aacgattgac
    16561 tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac atagttctga
    16621 agatctgctg cgttttggaa tctctttgtc ggatccaaga cttgaagacg ggatccctct
    16681 gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc gtcacgtggt
    16741 tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc atttcttcga
    16801 ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg ggtataagta
    16861 atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc ccctgtagcg
    16921 taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa gttcttcata
    16981 gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt tgtgtcatcc
    17041 ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg tgactgttca
    17101 tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt ttcacgcgca
    17161 ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact gcggtagcga
    17221 tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga tctctctggc
    17281 aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt gatacgatca
    17341 taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac ctcttcgata
    17401 gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc attattgctt
    17461 gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc tgtcgttcca
    17521 tgttgactgg caagactgat accataagta tcgacattat tcttagctag aagattgtta
    17581 aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc tttaccaaag
    17641 aagtctggat gatacataac taggtctttg acattcactt gaccatagtt aaagttatac
    17701 caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt gattttatct
    17761 acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc tgacaaaagt
    17821 tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc taaatagagc
    17881 tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc tgactggtaa
    17941 tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc atataagaat
    18001 tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag attggcaaaa
    18061 tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg aagtaagagt
    18121 ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc cttcatcata
    18181 actgcagata agagttcttt ttggtataag agactgttct ccttaaccag gtttccgtat
    18241 ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt ataaaccaaa
    18301 gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt gccacttgtt
    18361 gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt gcttacaatt
    18421 tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac gacctcatcc
    18481 ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt agctaccttc
    18541 attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac atcgctaaga
    18601 acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca caaatatcct
    18661 gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc cgcataactg
    18721 ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt ctgatctgac
    18781 ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga cgcatttttt
    18841 cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc ataggtattg
    18901 acaattcttc ccttgaaact gctctctgcg atgtttgatt ggtctgcctt agccaacaaa
    18961 ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt aatctttgtg
    19021 ccattcgtag cttcatttgc cagtgaacca atatcatttt tccctgaaat agcaacattt
    19081 tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg ttttttcaaa
    19141 ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt aaaggtgtcc
    19201 ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag gctggccgct
    19261 aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct aaaggaagta
    19321 aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt gtcgacatat
    19381 ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata aactgactgc
    19441 ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt aaatgctgaa
    19501 gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa tgaaacatgt
    19561 tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt tcttaattcg
    19621 agttttttct ctggttcttc taccatttta tcagggtcta gttcattttc ttgtttaatt
    19681 tcttcgtttc catttgaatt ggatgtgttt gattcggttg aaacatcctc agttgaattt
    19741 ccgtttgatg gttctgttgg tccattctct gatgttgtat tacctgaatt ttctggtttt
    19801 gttgcagttc tgtttttttc tggttgattt gattctccaa ctgaggttgt cgaatcacta
    19861 ggattactgg acacttcccc agtattttcg ctagatgtat ctggtgatac tttctctgaa
    19921 ttcgttgttg attcttctgc aggttgaact ggattttctg cttcttgaat tgaggttcct
    19981 tctgtagtac cttcatttgg atttactggt gtttcttctg ttggttttac tggaacttct
    20041 tcagtttttt ctggaccttg ttctttggtc ttctcaaccg gagtttcagg ttttacttgc
    20101 tcaatattcc ccttatattc tggcaatggt gctacctgct ctggttcacc tttatcactt
    20161 actacagctt cgggtaattc aggttggaca gcgggctcac ctttgtcggt tacaacagct
    20221 tcgggtaatt caggctgaat tgcgggctca cctttgtcgg ttacgactgc ttccggtaac
    20281 gctggttgaa cttctggtac gcctttatca cttactacag cttcgggcaa ctcaggctga
    20341 agtgcaggtt caacaatagc tccagattgt acgtccttat gttctacacc agtctcaggt
    20401 tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg aataggcgca
    20461 gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga gaatattctg
    20521 acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt tccttcagct
    20581 aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat agtttcctca
    20641 cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg tggatttaat
    20701 gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt ttctagattc
    20761 ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt tcttggattg
    20821 attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt agttgaagaa
    20881 acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa attcggtgta
    20941 acactataat ccaccttttg ttgttttata ggagtggcaa ctgaactctt ttgattactt
    21001 acttcagact cagaagttat gttttcctct ttgatatatc caatatatgt gtaacctgaa
    21061 atgtctttag gaagaggtaa tttttctcca gaggtcaatt tatagtcagt attgtaattt
    21121 agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc tatccctgca
    21181 accaatacta aatgtaatac cgttttattc ttaacctttt tcttggagac ggcaaaaatt
    21241 aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcatctc attcttgctt
    21301 ccagtatttg gcaattccgc cagttgactt tgagaattta acttataaac aagataataa
    21361 gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt cttttcttct
    21421 gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc ttgagcatcc
    21481 acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc agatacaagt
    21541 cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata cttttccatt
    21601 attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat tagtgtatta
    21661 tctattatct atagaaaagg cagtatacct taattatact cttaatttac aaaaaagtct
    21721 taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca ataacaccta
    21781 ccatgaaatt tacacggtag gtgttactca tatcagtaat cgttctaaaa atggtttgag
    21841 acagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat ggtcttcctg
    21901 caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt caaaggcttt
    21961 cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa agggtacttc
    22021 accacttttt ctatattcta ataagagcct agaaaatcga gctttttctt caggaagctc
    22081 acgaaaatag gaattgagga gccaagtctg attctgtttt ctttcaattg gatcctgact
    22141 ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggctttga tagcccgttc
    22201 tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag tcagggtctc
    22261 tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta gaaccagatt
    22321 gtctacatat tgcttggcga ttttatccct cttcttgcgt tctttctctg cctggatacg
    22381 gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga gttggtcatc
    22441 cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca tccgagcctt
    22501 tttctttagt tccgccttgg tccaacttcc tccctgaaag acttctagga aaagctggta
    22561 gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt tttcccagag
    22621 ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt cctttttctg
    22681 agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt ccaattgctg
    22741 gtcaagggac aatcgatgaa aatgacgaac acagtcgcta ccaattggaa agaggcgttg
    22801 gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttccac agacacaatt
    22861 gctacggccg ataccgttaa aaatcaagga aacttcattc cattccttgg tagcttgttc
    22921 ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc taactggaag
    22981 tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta gaaagctagc
    23041 cgcagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca
    23101 tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcaaagagt ataagttata
    23161 cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca atattttcaa
    23221 tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga tagcggtcta
    23281 cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca attttgtttt
    23341 cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga ctcttttggt
    23401 ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta gcaagaattt
    23461 cctgaccgag tactgtgtca aagaaagcaa gaattttatc aagattgatc ttgtctctga
    23521 cagcttggct agtttgaact tgtttgagtg tttctgttag gctagcaagg gttagttgct
    23581 ggctgaggtc aattctctgc atgagttcgt gagtagcact accaatctca gctccagtta
    23641 ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct actgactgac
    23701 cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat ttcttgattt
    23761 gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta ttataaactg
    23821 ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga ttgtctgctt
    23881 gggagctatc ttggagagga ctcttggttt ccaactctcc gataacttct ctggtcaact
    23941 gatcttcgcc aataaaacga taactaaagt tgagcttgtc cttagtaaac actttactga
    24001 tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta tttagtttcc
    24061 cattttgggc tgctgggtat tgcttggctt ccagcttttc acgagaaccc ttgccgacaa
    24121 gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc tgctcagaat
    24181 agcttgctag ctgtaattcc tcttcgttct gcctatagct cagactagga atggagagtt
    24241 tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttagca atatatttga
    24301 caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc ttgttgaaat
    24361 cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc ttgtggatgg
    24421 tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa tcgtgctggg
    24481 cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa ttgctctttt
    24541 caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca ggaccattcg
    24601 gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa atcaagtcat
    24661 agagagaatg ggttttggca tacaagcgcc aagaagctag gatatccatg aattgcttta
    24721 gtttttcagc tagagctgtg tgaatcaagc ctttttgact acttgccatt ttttgtgcat
    24781 tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga agggacaaac
    24841 gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca accaaggcgt
    24901 agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc acttctaggg
    24961 attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac tcagacaggg
    25021 caagtagaat ttggtcatta cgactacgac tagaggtcag aagggcaatt tccttaaagg
    25081 caacaccttt ttcctgatga agtttaagga tctccttgat aactaagcgc atttcgcctg
    25141 ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg tcgtagagga
    25201 gaaattcggc cttgttgtct ggattgggag tcagtttggt attggcaaaa acaagctggt
    25261 gcatgttatc atagttgatt tcgccgacct cttggtccat gagacgttca aagacatcat
    25321 tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga atgagcttac
    25381 cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc gggtctgcct
    25441 gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg tggccattag
    25501 acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca tcgaccatga
    25561 cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct aaaatctcaa
    25621 tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctgtcgtttt ctctgacgat
    25681 aagcctccac aaaatcgctc atgaaagatt ggaaggtttt agctagtttc caagtgtctc
    25741 catgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt cctagtttag
    25801 caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa tcagccttac
    25861 ggctggcatt agtcagagct cgaccgtttt tctccttaga gatggcaaca acatgcgcaa
    25921 gcactgcctg ataagcctga ctatcggact cctgatttag ggagccaatt tcatccagaa
    25981 ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg ttatccagat
    26041 ggtaacagaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca gtcagttttt
    26101 ctttttcact ggtaaaatca gctttctcaa agcctttgag gaaagattca ctcagccact
    26161 tttgaggatt gctggtggat tggaggaagt catagatttt atagacctgc tggcgcagac
    26221 cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag gtctctttct
    26281 gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg agaagaagtt
    26341 gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga taaccatgtt
    26401 tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttg ggtaggtctg
    26461 ccaactggcg acccaagtgt tgtttgagct cgacatcatc tgtttcttgg attttcttgc
    26521 tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta aaggttgaga
    26581 taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc tctgccatga
    26641 caaaggtctt tccagaacca gccgatgctg agaccaggat attctggcca gaagtgtaga
    26701 tagcttcgat ttgctcggca gttttcttct gttccttgct cgaatttgct tctgcttctt
    26761 gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat tcaactcctc
    26821 tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct tgctatcagc
    26881 taggtccaac ttttttagga aacgggcttg gcccagatgg taattggctt caaagcctgt
    26941 aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag tataaggatt
    27001 gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat aggcattgta
    27061 gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt tgttataaaa
    27121 ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca tagatttgct
    27181 ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga caggttcagc
    27241 catttccaaa tacatggcgc cgaaaaagtt ctgctcccct tctcttttta gggcagcaag
    27301 ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga actgagtcag
    27361 actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt caatccggtc
    27421 caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg cttggtcttt
    27481 tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc ggagaatatg
    27541 tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt ccaaactttc
    27601 ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt gttctagacg
    27661 ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac gatgcaagaa
    27721 attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc ctaaaacgta
    27781 gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg tagacaggta
    27841 aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg tcttgctgct
    27901 tggactggtt gggatagctg gattttccag accttgctga tctagttttt tacctatgac
    27961 acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct caccctgctg
    28021 gtgataggca accagactag acaaaagact gtgataggac cccatatcct ccttagacag
    28081 tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca actcttgaag
    28141 ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca agaacaactg
    28201 cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga gattttcact
    28261 gctggcaatc agtaattgaa cgccttcttc ggtcgcttgg tttaggtttt gcctttcttc
    28321 atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag ttagtccaat
    28381 agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca ccagaacagt
    28441 gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat ggagcaaggc
    28501 taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt gttctaaaac
    28561 atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt ccaaagtggt
    28621 tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac tccatttttg
    28681 taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag gtgctaaaat
    28741 tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg atttggtgaa
    28801 ggtttgctga aaggctggca agccattgat accaagatag cggatatatt gctcaaaagc
    28861 atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat taatcaaatc
    28921 ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact gagtcaaggg
    28981 atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact ggtcaaaaat
    29041 ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa aatgcttgta
    29101 gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta gctccaactc
    29161 ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct catcgacatc
    29221 caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct tgtcaaaact
    29281 atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt tagaagccag
    29341 atgatggaga aattttacgc tggcttggta aagattgccc tcgctaaaag gactggtata
    29401 ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt gaagtaagtc
    29461 cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca aggtgatttg
    29521 attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg acaactgact
    29581 tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa tcaagagtaa
    29641 atccgtcctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca tctgagattt
    29701 ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct gcttaatagc
    29761 gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa aggccaaccc
    29821 aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca gataacgagc
    29881 catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca agcattccag
    29941 cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga cccgcttgcc
    30001 agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag ttcgaatatc
    30061 agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat attataccat
    30121 gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt catcatctgc
    30181 taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggcc actgaaaatc
    30241 atataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc ttaggtacgg
    30301 aatacacttc aatgtgttgt cccagtgtct taatgtcgac gggtagattg tctgatttat
    30361 cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta cgtgccttta
    30421 tatattcaat attcttgata gaatgattga actatagtaa attgaaacta taatagtaca
    30481 ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag ctgttcgtat
    30541 cttatttcaa tctactatag taaaatgaac caaaaatagt acacaatgtg gtataatctt
    30601 cttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacaggt
    30661 agtataacag aagc
//
LOCUS       DAVHSL010000027        29844 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000027 DAVHSL010000000
VERSION     DAVHSL010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.027"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..1096
                     /locus_tag="VVR39_001193"
                     /pseudo
     CDS             1..1096
                     /locus_tag="VVR39_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1133..2692)
                     /locus_tag="VVR39_001194"
     CDS             complement(1133..2692)
                     /locus_tag="VVR39_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6030688.1"
                     /translation="MHYEHSRKGKHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(2932..3249)
                     /locus_tag="VVR39_001195"
     CDS             complement(2932..3249)
                     /locus_tag="VVR39_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6030689.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            3419..3961
                     /locus_tag="VVR39_001196"
     CDS             3419..3961
                     /locus_tag="VVR39_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU6030690.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            3961..4590
                     /gene="nth"
                     /locus_tag="VVR39_001197"
     CDS             3961..4590
                     /gene="nth"
                     /locus_tag="VVR39_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU6030691.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            4801..5322
                     /gene="pyrR"
                     /locus_tag="VVR39_001198"
     CDS             4801..5322
                     /gene="pyrR"
                     /locus_tag="VVR39_001198"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU6030692.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            5341..6264
                     /locus_tag="VVR39_001199"
     CDS             5341..6264
                     /locus_tag="VVR39_001199"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU6030693.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            6314..7393
                     /gene="carA"
                     /locus_tag="VVR39_001200"
     CDS             6314..7393
                     /gene="carA"
                     /locus_tag="VVR39_001200"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU6030694.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            7705..10881
                     /gene="carB"
                     /locus_tag="VVR39_001201"
     CDS             7705..10881
                     /gene="carB"
                     /locus_tag="VVR39_001201"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU6030695.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(11156..11965)
                     /locus_tag="VVR39_001202"
     CDS             complement(11156..11965)
                     /locus_tag="VVR39_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6030696.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(11967..12770)
                     /locus_tag="VVR39_001203"
     CDS             complement(11967..12770)
                     /locus_tag="VVR39_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6030697.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(12780..14267)
                     /gene="tacF"
                     /locus_tag="VVR39_001204"
     CDS             complement(12780..14267)
                     /gene="tacF"
                     /locus_tag="VVR39_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU6030698.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            14603..15310
                     /locus_tag="VVR39_001205"
     CDS             14603..15310
                     /locus_tag="VVR39_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU6030699.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            15315..16337
                     /locus_tag="VVR39_001206"
     CDS             15315..16337
                     /locus_tag="VVR39_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6030700.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            16354..17223
                     /gene="licA"
                     /locus_tag="VVR39_001207"
     CDS             16354..17223
                     /gene="licA"
                     /locus_tag="VVR39_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU6030701.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAAIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGTDEK"
     gene            17213..18091
                     /locus_tag="VVR39_001208"
     CDS             17213..18091
                     /locus_tag="VVR39_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU6030702.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            18103..18792
                     /locus_tag="VVR39_001209"
     CDS             18103..18792
                     /locus_tag="VVR39_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU6030703.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            18888..19736
                     /gene="dprA"
                     /locus_tag="VVR39_001210"
     CDS             18888..19736
                     /gene="dprA"
                     /locus_tag="VVR39_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU6030704.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGMAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            20620..21663
                     /locus_tag="VVR39_001211"
     CDS             20620..21663
                     /locus_tag="VVR39_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF389 domain-containing protein"
                     /protein_id="HEU6030705.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFCLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANPKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            21830..23917
                     /gene="topA"
                     /locus_tag="VVR39_001212"
     CDS             21830..23917
                     /gene="topA"
                     /locus_tag="VVR39_001212"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU6030706.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGNVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            24023..24382
                     /locus_tag="VVR39_001213"
     CDS             24023..24382
                     /locus_tag="VVR39_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU6030707.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            24475..25107
                     /locus_tag="VVR39_001214"
     CDS             24475..25107
                     /locus_tag="VVR39_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU6030708.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQLEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            25151..25807
                     /locus_tag="VVR39_001215"
     CDS             25151..25807
                     /locus_tag="VVR39_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU6030709.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            25826..26458
                     /locus_tag="VVR39_001216"
     CDS             25826..26458
                     /locus_tag="VVR39_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU6030710.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            26486..26920
                     /locus_tag="VVR39_001217"
     CDS             26486..26920
                     /locus_tag="VVR39_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU6030711.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            26932..27969
                     /gene="leuB"
                     /locus_tag="VVR39_001218"
     CDS             26932..27969
                     /gene="leuB"
                     /locus_tag="VVR39_001218"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU6030712.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            27966..28235
                     /locus_tag="VVR39_001219"
     CDS             27966..28235
                     /locus_tag="VVR39_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU6030713.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            28239..28598
                     /gene="leuD"
                     /locus_tag="VVR39_001220"
     CDS             28239..28598
                     /gene="leuD"
                     /locus_tag="VVR39_001220"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU6030714.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            28760..29384
                     /locus_tag="VVR39_001221"
                     /pseudo
     CDS             28760..29384
                     /locus_tag="VVR39_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            29547..>29844
                     /locus_tag="VVR39_001222"
     CDS             29547..>29844
                     /locus_tag="VVR39_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030715.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKK"
BASE COUNT         9124 a         5421 c         6351 g         8948 t
ORIGIN      
        1 ctagaattct ccttagaaag cgtcgtttca agtgctatca ttgttctaaa atgatggttg
       61 ctgaaacttc tatcgtcaag aagaatcatc aaatccctcg tatcatcaac caaaagattg
      121 ctcaaaagtt aattgaaaag atttctatga ccgatattgc ccatcagctt tccatctcaa
      181 cttcaactgt cattcgaaag ctcaatgact ttcactttga gcatgatttt tctcggcttc
      241 caaagattat gtcttgggat gagtatacct tcactaaggg aaagatgagt ttcattgcgc
      301 aagattttga taatcttaat attatcactg ttcttgaagg cagaacacaa gctgtcattc
      361 gaaatcactt tcttcgctac gatagagctg tccgatgtcg cgtcaaaatt attactatgg
      421 atatgtttag cccttactat gacttggata aacagcttcg ctttcaaatt tctaggctca
      481 ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc ttgatcgctt
      541 tcacattgta caacatctta gccgtgctat gagtcgtgtg cgtgttcaaa ttatgaatca
      601 atttcatcga aaatcccatg aatacaaggc tatcaagcgc tactggaaac tcattcaaca
      661 ggatagccgt aaactgagtg ataagcgatt ttatcgtcct acttttcgta tgcacttaac
      721 caataaagag attttaaaca agcttttgag ctattcggaa gacttgaaac accactatca
      781 gcactatcag ctcttgcttt ttcacttcca gaataaggaa ccagagaaat ttttcggact
      841 tattgaggac aatcttaagc aggttcatcc tatttttcag actgtcttta aaacatttct
      901 aaaggacaaa gagaaaatcg tcaacgccct tcaactaccc tattctaacg ccaaactgga
      961 agcgaccaat aatctcatca aacttatcaa gcgcaatgcc tttggttttc gaaactttga
     1021 aaacttcaaa aaacggattt ttatcgctct gaatatcaaa aaagaaagga caaaatttgt
     1081 cctttctcga gcttagcttt ttttcaaccc actacagttg acaaagagcc atttataaat
     1141 cttctaaatt aactagcttc aaaccgtgtt ctgtcatgcg atagatgatc gagcagactt
     1201 cttttaagaa acgacggtca tgcgaaacag tgatgagacc gcctggatag gttgcaaaga
     1261 gttttctgat ttggggttga gaagtgggag aaaagtttcg tgtgggttca tccagcagga
     1321 gaaagtttgg tttgcgcagg actaaatcca aaagcaggag ttttccctgt tgtccgccag
     1381 ataaggagcg aatttgatgc tgcatttctg gataactgaa attgagacta gctaggtgag
     1441 attggatttt ctgtagttcc tctttttccc cagttttgct gaggtaggct attggtgata
     1501 aatccaattg cagttttttg tggtaatctt gtggcataaa accaagggaa atctctcttt
     1561 tatcattcag aagttgcttt aatttggcta atagagttga tttcccaaca ccatttggcc
     1621 cgataatacc gattttttct tgcccacgga cagttagttg tagtttttga accaaaactc
     1681 ggtcgtcaat ggacaaattt tctttttcca gttggactaa gactttagaa gctggtaatg
     1741 gttggatgtc tgaaaagaaa agttggattt gttcctcttc aagtggcttt tgagtcatgg
     1801 actgagctgt cttttcgtag cgtttttctt gtgagaggac agttttcatc tttttagcca
     1861 ataggcgacc ggcagtacta tctttggtag ctcgaagcgc agtttctaca ttttgcttga
     1921 ctctccgatg tttttccatg gttttatcgt aggctctttg gttgttagca gcttgctgac
     1981 tttgtttggc aaaattagcc tttctctgct cactatagct atcatagtct aaatgctcta
     2041 ctagcgtttc cgcttcttta cggtgtttga ccagtcgcaa gtgaacaata gtgtctgccg
     2101 tttcagaaag aaagtcttca tcatgggaaa tgaaaataac ggtttgcctg gtcttttgaa
     2161 tctggccttt tagccaatca actgtctcaa ggtctaggtc atttgaaggt tcatctaaaa
     2221 atagaatctc aaagggtttg gctaactcat ggataagctg aattttcaaa gcttcgcccc
     2281 ctgatagatt gccaatctct tggtcacttg cgaaacgatt gctatcaaaa tgcaattcct
     2341 ccgccaaacg atagaggata ctgtagtcta aatcaataga atctaaaaag aagtagtcgt
     2401 gtaaagtttt cttttttagg tcctcaggga ctttttgagg aatgtaggcc agtgactgat
     2461 aatcagactg gatgtctccc ttgatagtga aatcagacaa atcttccccc attaaagttt
     2521 taagtaaggt tgatttacca tttccttctt cgccaataat agctaccttt tccccgtctt
     2581 ggatggtcat ggttaggtca gatacaagat ctcgtaaatc tttgttttgt gtgatggtta
     2641 gatgattgat ttttatcata tgttttccct ttctagaatg ttcatagtgc ataacaaaaa
     2701 agctctactt tacctagtag agcccaaagt ctatgtcaaa aaaactctat taacatgcca
     2761 gaaaaagagc ataaaagagc acacaaaaag agacaaaaac aagatctact aaataaaggt
     2821 tctttatttg atagacttag ttgttcatgt ctcccttacc tccgagtatt agtatcttta
     2881 tactatacct ttaaggaaat tttgtcaaca gaaaactgga aattctatgc tctaaaatcc
     2941 aaaaacaggt ccatagagac ttagtacgtg tttgacatgc tcgtaatgga ttttgtcata
     3001 gtttcgccaa gcagtgcgtg cttgattgtt tagttttagg ctacccagtc caatcagagg
     3061 actggtgggt tggtaaaatt tctcaagatc aattaagata ctgttgttca acttttccgt
     3121 ttttttgagc tcttgcatag tagtgtttag cagctcttgt agtcgaatat catctgccgt
     3181 accctgttta cagttttggt agcttttatt taacttggat aggagttgaa tgagtttctt
     3241 gtcttccatg tgagcatcct ccttgatctg atgtactctt tccctatagt atagcactaa
     3301 aaaacaaaac tatcatggta aatatgttaa aattttgaat tttaattaca aagtttggtg
     3361 tgctgatttg tagccttttc atggtataat caagagagta aatctttatg gaggaagtat
     3421 gaaattaaat attcaagaaa ttcgtaagca gtctgaaggt ttgaactttg aacaaacgtt
     3481 agatttagtt gatgacctgc gtgcacgtaa tcaagaaatt ttagatgtaa aagatatcct
     3541 tgcagttggg aaagtacaat atgaagaccg tatgtatttc ttagattatc aactatctta
     3601 taccattgtt cttgcttcga gtcgcagtat ggagccagtt gagttagttg aatcttatcc
     3661 agtcacggaa gttttcatgg aaggcgcaac taaccatcta aatcaagaaa ttttagatga
     3721 tgacttggtc ttgcccatcg aaaatggggc gcttgacctt gctgagagtg tatcagacaa
     3781 tatcctgcta aacattccta tcaaggtctt gacggctgaa gaagaagctg gtcaaggatt
     3841 tgtctcagga aatgactggc aaatcatgac agaggaagaa taccaagctc aacaagcagt
     3901 aaagaaagaa gaaaacagtc cttttgctgg cttacaagga ctatttgacg gagatgaata
     3961 atggtcttgt caaaaaaacg agcacgaaag gtgctagaag aaatcattgc cctcttccca
     4021 gatgccaagc ctagtcttga ttttaccaat cattttgaac tcctggttgc ggtcatgtta
     4081 tcagcccaga cgacagatgc agcggtaaat aaggccacac caggtctctt tgttgccttt
     4141 ccaacacccc aagctatgtc tgtagcgaca gagagtgaga ttgcttcaca tatttctcgc
     4201 ttgggattgt atcggaataa agctaaattc cttaaaaaat gtgcccaaca gttactagac
     4261 gattttgatg gtcaagtccc tcagacacgt gaagaattgg agagtttggc aggtgttggt
     4321 cgcaagacag ccaatgttgt catgagtgta ggatttggga ttccagcctt tgcagtggat
     4381 actcatgtgg agcgtatttg caaacaccac gatattgtca aaaaatcagc gacgccactt
     4441 gaggtggaaa agcgggtcat ggatatcttg ccgcctgagc agtggttagc tgcccatcag
     4501 gccatgattt attttggaag agccatttgc catccaaaaa atccagagtg tgaccagtac
     4561 ccacaattat atgattttag caatttgtaa gatactacat tgaaactttt tgcttgattt
     4621 taagcatgct ttgtgctata gtaaatgata actaaatatt cctttaaacc tgtcccgtga
     4681 ggcaggcaag gagcgcgata aagtagaagg gtgaagtcta tactgtgtgc agtagggctc
     4741 gcttggctat aaatttcaag tctccttgtt taaggagact tttctttttg gaggtttgtc
     4801 atgaaaacaa aagaagttgt agacgaattg accgtcaaac gagcgattac gcgtattact
     4861 tatgagatta tcgaacgcaa caaagatttg aataagatcg tcttggctgg tattaaaact
     4921 cgtggtgtct ttattgccca ccgaatccaa gaacgtttga agcagttaga aaatctttca
     4981 gttcctgttg tggaattgga tactaaacct ttccgtgatg atgttaaaag tggagaagat
     5041 acttctttgg tttctgtcga tgtgacagac cgcgaagtta tcttggtgga tgatgtgctc
     5101 tatacaggtc gtaccatccg tgctgctatt gataatattg tcggtcatgg tcgtcctgcg
     5161 cgtgtgagtt tagcagttct agtcgatcgt ggacatagag aattgccaat ccgtccagat
     5221 tacgttggaa aaaatatccc aaccagtcgt tctgaagaaa tcatcgtaga gatgacagaa
     5281 cttgatgacc aagacagagt tctgattact gaagaagctt agaaagttaa aggagtagcc
     5341 atgtcagaaa atcaacaagc attgaaccat gtggtgtcca tggaagacct cactgtcgat
     5401 caagtaatga aattgatcaa gcgaggaatt gagtttaaaa atggagccca gcttccctat
     5461 gaagaccatc cgattgtttc caatctcttc tttgaggatt ctacacggac acataagtcc
     5521 tttgaagtcg cagagattaa acttggattg gaacgacttg actttgatgt gaagactagt
     5581 tcggttaata agggtgagac actttatgac accattttga ctctgtctgc tttaggagtg
     5641 gatgtctgtg tgattcgcca tccagaggtc gactactata gagaattgat tgctagtcca
     5701 acgattacga cttccatcat caatggtgga gacggttcgg gtcaacaccc tagccagagc
     5761 ttgcttgatt tgatgaccat ttatgaggaa tttggccact ttgagggtct taaagttgct
     5821 attgcaggtg acttggacca ctcacgcgtt gccaaatcca atatgcagat tttgaaacgc
     5881 ttgggagctg aactcttttt cgctggacct gaggaatgga gaagtcaaga gtttgcagac
     5941 tatggaaagt ttgtaaccat tgatgaaatc attgatcagg ttgatgtcat gatgtttctc
     6001 cgtgtgcaac acgaacgcca tgatagtgga gctgtatttt caaaagaaga ctaccatgcc
     6061 caacatggct tgactcaaga acgttacgat cgtttgaaag aaacagcaat cctcatgcac
     6121 ccagctccaa tcaatcgtga tgtagaaata gcagaccact tggttgaagc accaaaatca
     6181 cggattgtcc aacaaatgac caatggtgtc tttgttcgaa tggcaatctt agaatccgta
     6241 ctagcgagta gaaacgccaa ctaaaacaca agacgttaaa agacaccagt gagcgtccac
     6301 gagaggtgaa aatatgacaa aaagaattct agtattagaa gatggcacag tttttgaagg
     6361 caaggccttc ggagcagata ttgatgtaac aggcgaaatc gtctttaata cagggatgac
     6421 cggctaccaa gaatccatta cagaccagtc ttataatgga caaatcttga cctttactta
     6481 tcctttggta ggaaattatg gtattaatcg tgatgattat gaatccatta ttccaacttg
     6541 taagggagtc gttgtttttg aagaagcgcg tagagctagc aactggcgca accaaatgac
     6601 cttggatgaa tttttgaaag ccaagaaaat tccagggatt tcaggaattg atacgcgtgc
     6661 tcttaccaag attatccgta agcatggtac tatgcgtgca accttgaccc atgttgggga
     6721 cagtatggac catgtgacgg accagctcca agcaacagtt ttaccgacag acaatatcaa
     6781 acaggtttct actaaaacgt cttatccagc tccaggagtt ggtttgagcg tggtgctagt
     6841 ggactttggt ctcaagcact caatcctacg tgaactttct aaacgcaact gtaacgtgac
     6901 agttgttcct tattcgacaa cggctgaaga aattctccat ctcaatcctg atggagttat
     6961 gttgtcaaat ggtccaggta acccagaaga cgttccacaa gcactcgaca tgattcgcgg
     7021 tgtacaagga aaaattccaa tctttggtat ttgtatggga caccaactct ttgcaatggc
     7081 aaacggggct aagacctata agatgaagtt tggccaccgt ggattcaacc atgcggtacg
     7141 tgaaatcgca acaggacgag tagacttcac cagccagaac catggttatg cagtcagccg
     7201 cgaggatttg ccagagcact tgattattac ccacgaagaa atcaatgaca agtcagtgga
     7261 aggtgtgcgc cacagatacc aacctgcttt ctctgttcaa taccacccag atgcagctcc
     7321 tgggccacac gacgctagct acctatttga cgagtttatc gagatgatgg aagtttttaa
     7381 acaatcaaac taagaacgag taaaagctcg tcggagaatt tatgtaactg aacacggacg
     7441 gaaagctcag aatgtagaga aaccaacttg gattgtcaat ccttccttga tttcctaaaa
     7501 ttcaatcgct ttctattcgt cctttgtatc ttatttaatg tcgccctgag aggcgacgaa
     7561 tagaaaggag aagatacatt gttcgcggaa gtgaacacgc cctaagaact gtgtgaaaaa
     7621 gataaacatc gtcttgacgc tgaaggcgtc tgcgccgagt ttcctatttt cactgtgttc
     7681 tttacgggct ttgtatcata aactatgcct aaacgtactg atattcaaaa aattatggtg
     7741 attggttctg gtccgattat tattggtcag gctgctgagt ttgactacgc tgggacccag
     7801 gcttgcttgt cgttgaaaga ggaaggttat gaggttgttt tggttaactc aaatcctgca
     7861 accatcatga cggacaagga aattgctgac aaggtttaca ttgaaccgat tacacttgag
     7921 tttgtgacac gtattcttcg taaggaaggt ccagatgcct tgctaccaac actcggtggt
     7981 cagacaggtc tcaacatggc catggaattg tctaaaaatg gtatcttaga tgagcttggc
     8041 gttgaacttc tgggtaccaa attatctgcc attgaccaag cggaggaccg tgacctcttt
     8101 aaacaattga tggaagagct tgaacaaccc attccagaat ctgaaattgt taacacagta
     8161 gaagaagcag ttgcctttgc agcgacaatt ggctacccag tcatcgttcg tccagccttt
     8221 accctcggtg gtactggtgg tggtatgtgt gccaatgaga aagaattgcg tgaaatcact
     8281 gaaaatggtt tgaaattgtc acctgttacc caatgtttga ttgagcgttc gattgccggt
     8341 ttcaaggaaa ttgaatacga agtgatgcgt gactcagctg acaatgcctt ggttgtttgt
     8401 aacatggaaa actttgaccc agttgggatt cacacggggg attccattgt atttgcccct
     8461 gcgcaaacca tgtcagacta tgaaaaccaa atgcttcgtg atgcgagctt gagcattatt
     8521 cgtgccctca agattgaagg tggatgtaat gttcagctag ctcttgatcc taacagcttc
     8581 aagtattatg ttatcgaagt aaaccctcgt gtatcacgtt cgtcagccct tgcttctaaa
     8641 gcgactggat atccgattgc taagttggct gccaagattg cagtaggttt gaccttggat
     8701 gaggttataa acccagttac aggttcaacc tatgccatgt ttgaaccagc ccttgactac
     8761 gtagttgcta agattccacg tttcccattt gacaagtttg aaaagggtga acgccgtctc
     8821 ggtacacaaa tgaaggcgac tggagaagtc atggcaatcg gtcgtaatat cgaggaatct
     8881 cttctcaagg cctgccgctc ccttgaaatt ggggtgcacc acaatgaaat acctgaactt
     8941 gcagcagttt ctgatgatgc cttgattgaa aaggttgtca aagcccaaga tgaccgtctc
     9001 ttctacgtat cagaagcaat tcgtcgtggc tacacacctg aagaaattgc agagcttaca
     9061 aaaattgata tcttctatct tgataaactt ttgcatatct ttgaaattga gcaagaattg
     9121 ggtgctcatc cacaagatct agaagttttg aaaacagcca aacttaatgg tttctcagac
     9181 cgtaagattg ctgaactctg gggaacgact gatgatcaag ttcgccaact tcgcttggaa
     9241 aacaagattg ttccagttta taagatggta gacacttgtg cggcagagtt cgactccgaa
     9301 acgccatatt tctattcaac ctatggttgg gaaaatgaat ctatcagatc tgataaagaa
     9361 tctgtacttg tcctaggttc aggtccaatc cgtatcggtc aaggggttga gtttgactac
     9421 gcaaccgttc actctgttaa ggctatccag gcagctggtt atgaagctat catcatgaac
     9481 tcaaacccag agaccgtttc aacagacttc tctgtatcag ataagcttta ctttgagcca
     9541 ttgacattcg aagatgttat gaacgtcatt gacttggaac aaccaaaggg agttatcgtt
     9601 cagttcggtg gtcaaacagc catcaacctt gcggagccat tggcaaaagc aggtgtgacc
     9661 atccttggta cacaggttgc tgacctagac cgtgccgaag accgtgacct cttcgagcaa
     9721 gctctcaaag aattggatat tccacagcca ccaggacaaa cagctaccaa tgaagaagaa
     9781 gcagctcttg cagctcgcaa gattggcttc ccagttcttg tccgcccatc ttatgtactt
     9841 ggtggacgtg ccatggaaat cgttgaaaac gaagaagacc ttcgttctta catgcgaact
     9901 gctgttaagg ctagtccaga ccacccagtt cttgtcgact cttatatcgt tgggcaagag
     9961 tgcgaagttg atgccatttc agatggtaaa gatgtactca ttcctggtat catggagcat
    10021 atcgaacgtg ctggtgtcca ctcaggtgac tcaatggctg tttacccacc acaaaccttg
    10081 tcgcaaaagg ttcaggagac catcgcagac tacaccaaac gcttagcaat cggtcttcac
    10141 tgccttggaa tgatgaacat ccagtttgtt atcaaggatg aaaaagtcta cgttattgag
    10201 gtcaatccac gtgccagccg tactgttcca ttcctatcta aggtaaccaa tattcctatg
    10261 gctcaagtag cgaccaagct cattcttggt caaagtttat cagaacttgg ctaccaaaat
    10321 ggactttacc ctgaaagcac ccgtgttcat atcaaggcac ctgtcttctc ctttaccaaa
    10381 ctagctaagg tagacagctt gctcggtcct gaaatgaagt caacaggtga agttatgggt
    10441 tctgatgcta ctttggaaaa agctctctat aaagcctttg aagcttctta tctacacttg
    10501 ccaacttttg gtaatgtcgt ctttaccatc gctgatgatg ccaaagaaga agccttgaac
    10561 ttggctcgtc gtttccaaaa cattggttat ggaatccttg cgacagaagg gacagcagcc
    10621 ttctttgcta gccatggctt gcaagcccaa cctgttggta agattggtga tgacgataag
    10681 gatatcccaa gttttgtacg caaaggaaga attcaagcta tcattaacac agtaggaaca
    10741 aaacgaactg ctgacgaaga tggtgagcaa attcgtcgtt cagccattga acacggggtg
    10801 cccctcttca cagcgctaga tacagctaat gccatgctta aggtacttga aagtcgtagc
    10861 tttgttacag aagcgattta aatagaaaaa taaggtatag cagactgaat ttagaacagt
    10921 acacagggat actaaaatat ttctagaaat taatttgaat tttctaattg atttgttcgc
    10981 atcttatttc aatctactat agaaaaaagt ctttaaaatt ataaaacgca tcatatcaag
    11041 atttttcaaa aaccttgata tgatgcgttt tattgtggga atatgtattt cattttctac
    11101 taaaattatg tttttgaata acctctatct tagtagtttg tataatcccc ctcaatcagt
    11161 ttttgcgata agctttaatg ctatgactat accactcttg catttctttt gatggtggtg
    11221 tcatataatc gccatacatc tgggttaaaa attggtcata ttttttggga acaggcaaca
    11281 tacggccctc aaactcagtt aaaatcagtt ctttaaaggt atcaactggg aagatttctt
    11341 tcatcccttc cttaccgatc ccaactcctc cttcatattg aggagtgttg gttacagcat
    11401 ttttgactag ttgatcaatt ttcttgtaaa agtagcgagg attgacaaat cggagagcgt
    11461 accagctaca taatctaaga aaatctttta gtttgctatc accgtgaact gctcgtgatt
    11521 ttttgatata agctagttga cgaagagcca catacttata gctcttgtcg acaatgctca
    11581 agtctgtaaa tcgatcaatt gggaagacat cgatgaaaag gctggtatca tgacgcttgt
    11641 acttaacatg gtcttctata acagtagaag tgtccaaaat cgatgcgaaa ttatggaagt
    11701 accaagaaga tgtatcgtag gaaagaacct tgtagcgagg gtgattttct tcttcaataa
    11761 tcttcagtaa acgctcataa tcctcacgat aaagggaaat atcaatatca tcatcccaag
    11821 gaatcatacc tttgtggcgg atggctccaa gcatggttcc ataactgaga aaataaggaa
    11881 tatcatattt cttacaagtc tcatcaatat agtccagcag ggctagttga atttctttaa
    11941 tttctttttt ttctaaatat tgcatcctaa tcctccaatt tataagcgtg aaattcatga
    12001 ctgtagaagc gtttttcttc tggtggtagg gtcatataat ctccataaaa ttgtgtcaaa
    12061 atagtatcaa atttttcagg tgcaggaagg cttaaattct caaagggtaa atcgattgtt
    12121 ttatcaaagg taccacttgg gaagacttcc ttttccttaa attttgaagg gataaaagcc
    12181 atatattgcc cattttcacg actatatttt tgaatttctt tctcgatttt atttgcaaaa
    12241 taacgaggag aaaccggtcg aaggagtaac cagaaggctg ttcgtatcca atcttttaaa
    12301 aggctatcct tatagacaat atttttatgt ttactgaaag acagcagttt gaagctttcc
    12361 agtttataac aagtatcaat gaccttagga tcatcaaagc gatctatagg gaaaatatcg
    12421 ataaagatac cagactcata ggtttttgta tttcgagtat caataatttt agtcgtactg
    12481 tcggttatct tgataaagtt gttaaagtag ttcttatcag tttctaagga taggagctta
    12541 tacttgcttt tttccttttg aaaaatgtta ataaatcgtt ggtagtcttc tctaggcatg
    12601 gataaatcaa tatcgtcgtc ccaagggata aagccctcat gtcgaaccgc cccaatcaga
    12661 gtaccgtagt taataatata gttgatattg tgctttttac agagagtatc aatataatcc
    12721 aaaatttcta attcaatttg tttggcatct tcaatggtta gttgtttcat tttaaactcc
    12781 tatgattttt tgaatttatt ttttaaggct aggacatggt ttaaaaattc atagaaaatg
    12841 ctatcttttg tgaagacaag tagactaata taagagatag ctgatagcaa gacaatcaaa
    12901 ccagtattaa ttaaaaatgg caaattaatg accatatcca caggatacac gaaattaatc
    12961 aggaaataaa ttgctacaaa ggaaagtgaa aagagagagt atcgaacagt atagctaaag
    13021 atatgtccca agtggatgag ttgttttcta tggatgaaaa taatatagaa aacaagtaga
    13081 gaagtctctg ataacatagt tgtcagtaag tagtattcag gaaccacgat atggttgaaa
    13141 aagaggagac tattcaagcc caaattgagt agcccagcaa agactgtata gactgtgata
    13201 cgtttttcat agccattggt aaagagaatt tgggaaccaa gaatggtatc taaggccagg
    13261 ataatcgtac gaaaagcgaa gagagaggtc aagatgccgc ctccgatata tttttcacta
    13321 ccgtaaagta ggatggcatt tggtcctaaa accatgagtc caaaactcag tggaatgata
    13381 aagaagttaa agattcgact acctctatta accagagaaa cataggcttc tttgtctcct
    13441 ttccccagat agtaactgag acgaggcaca ctcactccaa ttgcacctgt tacaacccca
    13501 gctataacgg tcacaattcg ctgagctatg gtatagtaac taacgttgac atcaatccct
    13561 gttttaacga ggaagaggcg atctaaaaaa gtgaagagca tattggcatt ggcaaagact
    13621 aacatggctg tcagagggag aaagagtggt ttaaaatcac ttaggtgaat cttaacaagt
    13681 ttgatgtctc ttttaatcca aaaataacta atcaggtagt taatcagcgt cgataaactc
    13741 atcacaagtg tatagacaac aatatcgtgt tcatttttaa caaataagaa aatagagacc
    13801 agcatcagga tacggatgaa ggcagttttg taaaagagaa aactgtaatt ttccagagct
    13861 tcattgaccc attcgattga aaaaatctgg gcaatgagtt gaatccccat aacaaggtag
    13921 acctttttga cgattggatt atcaataaag aagagaggat aggctaggat atagacagca
    13981 gtggtcaaaa tcgtacaagc gatgcacaaa taaaaaagac tagaaaaggt tctgttaaga
    14041 tcttttttgt tatccttgac attactgata gcccttaaac cgtagttata gacaccataa
    14101 gttgcaaagg gcaagaaaaa tgacaaaata gtgtcgactg agttgaagta accatagtca
    14161 gttcggtcca agacacgcgc gacataggtt ccagttagga tgggaaaaat aatattcaag
    14221 acacgaattc ccatgtaaga tagagcattt aattttatac ttttcattca atttacctcg
    14281 tttttcatta tatcataaag ttagctaata agaaatgaag ggcagtaagt caagtaatca
    14341 ctttgaagtt tcaaatctta agttttaagt tttctttaag gaaagtatat tattctgaag
    14401 gactctaaaa tttcgcagcc atttattagt aattgctaca gaattcctag tcattactag
    14461 aaatggacta gtttctttga ataatagaac tgcataattc tcctattcta gaaggggagg
    14521 accagtattt cttttatgat aggactagat tgtggtataa tagagagaat aagttttttt
    14581 agtaagacaa aggagaaaat agatgattta tgcaggaatt cttgccggtg gaactggcac
    14641 acgcatgggg atcagtaact tgccaaaaca atttttagag ctaggtgatc gacctatttt
    14701 gattcataca attgaaaaat ttgtcttgga gccaagtatt gaaaaaattg tagttggtgt
    14761 tcatggagac tgggtttctc atgcagaaga tcttgtagat aaatatcttc ctctttataa
    14821 ggaacgtatc atcattacaa agggtggtgc tgaccgcaat acaagtatta agaaaatcat
    14881 tgaagccatt gatgcttatc gtccgcttac tccagaggat atcgttgtta cccacgattc
    14941 tgttcgtcca tttattacac ttcgcatgat tcaggacaat atccaacttg cccaaaatca
    15001 tgacgcagtg gacacagtgg tagaagcagt tgatactatc gttgaaagta ccaatggtca
    15061 atttattaca gatattccaa atcgtgctca cctttatcaa ggacaaacac ctcaaacatt
    15121 ccgttgcaag gacttcatgg acctttatgg atctctttct gatgaagaga aggaaatctt
    15181 gacagatgca tgtaaaatct ttgtgatcaa aggaaaagat gtggccttgg ccaaaggtga
    15241 atactcaaat ctgaagatta caaccgtaac agatttgaag attgcaaaaa gtatgattga
    15301 gaaagactag taaaatgatt aatcaaattt atcaactaac taagcctaag tttatcaatg
    15361 tcaaatatca ggaagaggct attgaccaag agaatcatat ccttatccgt cccaactaca
    15421 tggctgtctg tcatgcggat cagcgttact atcagggaaa acgtgatccc aagattttga
    15481 ataaaaagct tccaatggca atgattcacg agtcatgtgg aaccgtcatt tctgacccga
    15541 ccggaaccta cgaggttggt caaaaagttg tcatgattcc caatcagtct cctatgcaga
    15601 gtgatgaaga attctatgaa aactacatga cagggaccca tttcttgtct agtggatttg
    15661 atggctttat gagagagttt gtttctctcc ctaaagatcg tgtggtggct tatgatgcta
    15721 ttgaagatac ggttgcagcc attacagagt ttgtcagtgt gggcatgcac gctatgaatc
    15781 gtctattgac tcttgctcat agcaagcggg agcggatcgc cgttattgga gatggaagtt
    15841 tagcttttgt ggttgccaat attatcaact atactttgcc agaatcagag attgtggtta
    15901 ttggtcgtca ttgggaaaag ttggaactct tctcatttgc caaagaatgc tatattacgg
    15961 ataatattcc tgaagagttg gcctttgacc atgcttttga atgttgtggt ggtgatggta
    16021 ctggaccagc tattaatgac ttgattcgct acattcgtcc tcagggaacg attctcatga
    16081 tgggagttag cgaatataaa gtcaatctca atactcgcga tgccttagaa aagggcttga
    16141 ttttggttgg gtcatctcgt tctggtcgca ttgattttaa aaatgctatc caaatgatgg
    16201 aagtcaagaa atttgccaat cgtcttaaaa atatccttta tctagaagaa cctgtaagag
    16261 aaattaaaga tattcatcgt gtctttgcaa ccgatttaaa cacagccttt aaaacagtgt
    16321 ttaagtggga agtataagta ctggaggtta attgtggaga aaatcattaa agaaaaaatt
    16381 tcttccttac ttagtcaaga agaggaagtc ctcagtgttg aacaactggg tggaatgacc
    16441 aatcaaaact atttggccaa aacaacaaat aagcaataca ttgttaaatt ctttggtaaa
    16501 gggacagaaa agcttatcaa tcgacaagat gaaaagtaca atcttgaact actaaaggat
    16561 ttaggcttag atgtaaaaaa ttatcttttt gatattgaag ctgctatcaa agtaaatgag
    16621 tatatcgaat ctgcgattac gcttgattca acgtcaatca agaccaagtt cgacaaaatt
    16681 gctccaatat tacaaactat tcatacgtct gctaaggaat taagaggaga atttgctcct
    16741 tttgaagaaa tcaaaaaata cgaatccttg attgaagaac aaattcctta tgccaactat
    16801 gaatctgtta gaaatgcagt cttctcctta gagaaaagac tggctgactt aggtgttgac
    16861 agaaaatctt gtcatatcga tttggtgcct gaaaacttta tcgaatcacc tcaaggacga
    16921 ctttatttga ttgactggga atattcatca atgaatgatc caatgtggga tttggctgcc
    16981 ctctttttag agtctgaatt cacttcccaa gaggaagaaa ctttcttatc tcactatgag
    17041 agtgaccaaa caccggtttc tcatgaaaag attgctattt ataaaatttt acaagatact
    17101 atttggagtc tatggactgt ctataaggaa gagcaaggtg aagattttgg tgactatggt
    17161 gtgaatcgtt accaaagagc tgttaaaggt ttggcttctt atggaggaac agatgaaaag
    17221 taaaaacgga gttccttttg gccttctctc aggtattttc tggggcttgg gtctaacggt
    17281 tagtgcttat atcttttcga tttttacaga tttgtcaccc tttgtggtgg ctgcagctca
    17341 tgattttttg agcatcttta tcttactagc ttttctcttg gtaaaagaag ggaaagttcg
    17401 cctctcaatt ttcttaaata ttcgcaatgt cagtgttatc atcggagcct tgctagcagg
    17461 ccctatcggt atgcaggcca atctttatgc agttaagtat atcggaagtt ctttagcttc
    17521 atctgtatcg gctatttacc ctgcgatttc agttctattg gctttcttct ttttgaagca
    17581 caaaatttcg aaaaatactg tatttgggat tgtcttgatt attggaggga ttattgccca
    17641 gacctataag gttgaacagg ttaattcctt ctacattggg attctctgtg ctttggtttg
    17701 tgctattgca tggggaagtg agagtgttct tagctccttt gctatggaaa gtgaactgag
    17761 tgaaatcgaa gccctcttaa tccgtcaagt gacttcgttc ttgtcctatc ttgtgattgt
    17821 gctcttctct catcagtcat ttactgcagt agccaatgga caattgctag gtctcatgat
    17881 tgtttttgca gcctttgata tgatttccta cttggcttat tatatcgcta tcaatcgctt
    17941 gcaaccagcc aaggctacag gcttgaacgt gagctatgta gtatggacgg tcttgtttgc
    18001 agttgttttc ttgggtgcac cgctagatat gctgaccatt atgacgtcac ttgtcgtcat
    18061 tgctggagtt tatattatta ttaaagaata aaggagattc gtgtgaaagc cattatctta
    18121 gcagcgggat tgggaactcg cttgcgtcct atgactgaaa atacccctaa agccttggtt
    18181 caggttaatc aaaaaccttt gattgaatac caaattgagt ttctcaaaga aaaaggaatc
    18241 aatgacatca tcatcatcgt tggttatctt aaagaacaat tcgattattt aaaagaaaaa
    18301 tacggtgttc gcctcgtttt caatgataaa tacgctgact acaataactt ttactctctc
    18361 tatcttgtaa aagaagaatt ggccaacagc tatgttattg atgctgacaa ttatctcttt
    18421 aaaaatatgt tccgcaatga tttgacacgt tcgacttatt ttagtgttta tcgtgaagat
    18481 tgtaccaacg aatggttctt ggtctatgga gatgactaca aggttcaaga cattattgtt
    18541 gatagcaagg caggtcgcat ccttagtggt gtatccttct gggatgctcc aactgcagaa
    18601 aagattgtca gctttatcga caaggcttat gcaagtggcg aatttgttga tctctactgg
    18661 gacaatatgg ttaaggataa tatcaaagag ctagatgtct atgttgaaga attagaaggc
    18721 aatagcattt atgagatcga tagtgtccaa gactatcgta aattagaaga aattcttaaa
    18781 aacgaaaatt aaagattcca acatctgaca aaatagtcgg atgttttttg attttttacg
    18841 aacttttacg aatagataga tgagtagaaa aagaaatgga gttatttatg aaaatcacaa
    18901 actatgaaat ctataagtta aaaaaatcag gtttgaccaa tcaacagatt ttgaaagtgc
    18961 tagaatacgg tgaaaatgtt gatcaggagc ttttattggg tgatattgca gatatctcag
    19021 gttgccgtaa tccagccgtt tttatggaac gttattttca gatagacgat gcgcatttgt
    19081 cgaaagagtt tcaaaaattt ccatctttct ctattttaga tgactgttat ccttgggatt
    19141 tgagtgaaat atatgatgcg cctgtacttt tattttacaa gggaaatctt gacctcctga
    19201 aattcccgaa ggtagcggtc gtgggcagtc gtgcttgtag caaacaggga gctaagtcag
    19261 ttgaaaaagt cattcaaggc ttggaaaatg aactggttat tgtcagtggt atggccaagg
    19321 gcattgacac agcagctcat atggcagctc ttcagaatgg cggaaaaacc attgcagtga
    19381 ttggaacagg actggatgtg ttttatccta aagccaataa acgcttgcaa gactacatcg
    19441 gcaatgacca tctggttcta agtgaatatg gacctggcga acaacctctg aaatttcatt
    19501 ttcctgcccg taatcgcatc attgctggac tttgtcgtgg tgtgattgta gcagaggcta
    19561 agatgcgttc aggtagtctc attacgtgtg agcgagcaat ggaagaagga cgcgatgtct
    19621 ttgctattcc tggtagcatt ttagatggac tatcagacgg ttgccatcat ttgattcaag
    19681 aaggagcaaa attggtcacc agtgggcaag atgttcttgc ggaatttgaa ttttaaaaat
    19741 gacctaagct agaattctaa gaaaaaatca attttaagag aaaatgaacc caacatttcc
    19801 ataataaaac gcatattagc aagtttttaa cacttgataa tatgcgtttt ttctaagtgg
    19861 attagtagag tagaggattt ttctcatata atactcttcg aaaatctctt caaactacgt
    19921 cagcttccat ctgcaacctc aaaacagtat tttgagctga cttcgtcagt cttatctaca
    19981 acctcaaagc agtgctttga gcaacctgtg gctagcttcc tagtttgcgc tttgattttc
    20041 attgagtata agggaaagta tagtgaattg aaataagatg tgaacaactc tatcaggaaa
    20101 gtcaaattaa tttatagaaa tattttagca gccaaggtgc actgttatag attcaataca
    20161 caataattta gtgtaattga gaaaggagaa atgattgtga ttgatgttgg ctaggttatg
    20221 ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa aaataaattc ttcaaaagta
    20281 gagattacaa ggcttgttta agaaagaatt caaagacctt gacaaataaa aataaaatgg
    20341 ttattataag aaatggtcta aaatagatga tgatactttt cgaaaatctt tttacgtcag
    20401 ctcagctttg ccttgctgtg ttttgagcaa gctacggtta gcttccgagt ttgattttca
    20461 tttactagaa atgaaactga tgagagatat cagtagacat ttgagtcagg atattatgga
    20521 aaatgataaa aagagctcgt gagattggca tatcagacta ctaaagtatt gagtttgtta
    20581 ggattttagc gactagttag ctgggaaagg aagatatttg tgacaaataa taaactgtat
    20641 tcgttgatag aatttagaaa taaaatatat gaagaattag aactttccag aagtgattta
    20701 gcgattttac tatgtgccat gcttatcgcc tctatcggat taaatatgga ttcgactccc
    20761 gtgattattg gagccatgtt aatctctcct ttgatgacac ctattctggg agtggggctc
    20821 tctctagcta tatttgattt taaattgtta agaaaatctt ttaaaatatt agctattcaa
    20881 attcttgcca gtctaatagc ttcaacactt tatttttgtc tttctcccat ttcgtatgct
    20941 agttcggaga ttgttgctag aacctctccg actatttggg atgttctcat tgcttttgta
    21001 ggagggatag caggtattat tggtgctagg aaaaaagaga ccaataatat tgttcctggt
    21061 gttgctattg caaccgcctt gatgcctcct ctttgtacag taggttatgc tattgcttct
    21121 gctaatccaa aatttatcat aggctcctct tacctattcc tcatcaattg tagctttatt
    21181 gtcattgcga cttatatagg tgttaggttg atgatggtta agaaacatta ttttaaagat
    21241 aatgaagaag actctaaaat gcgtaggatt ttgcttctag ttgctgtttt gctgatgatt
    21301 ccgagtttta tttctgcaac gactttagtg agagaaacgt tgaaaaaaga gtcccttaag
    21361 aaatttatat cagagcagtt tcaggggtat aatattttga aaaaaaccta ttctaaaaag
    21421 actcataccc taaagctaac catttcagga aattatttga cagaagaaga actcgatatg
    21481 atttcaagta agagaggtga ctatggttta agtgatgttt ctgttcaagt ttcacaattg
    21541 tctgattcag aacaacttag taaggaagag ctggtggagt atttcttcca gtatatcaag
    21601 gataaggaag caaaagaaaa ggagaaggcc aataaatttg atacagagtc tgaggagcaa
    21661 taatttcttg agaatagctg gtttctctcg tgagtcttct atgtatatca aaggaagact
    21721 gaggttttaa gtataaaact tttcttctat tatagtagct aagtcttgac agggttcaaa
    21781 aaatggttta cactttataa agtttattac tttgaaaagg tgtgatactg tggctacggc
    21841 aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc atcgtggagt cgcctgctaa
    21901 ggccaagacg attgaaaaat atctaggcag aaactacaag gttttagcca gtgttgggca
    21961 tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt gaaaataatt atgaaccgca
    22021 atatattaat atccgaggaa aaggccctct tatcaatgac ttgaaaaaag aagctaaaaa
    22081 agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa ggagaagcga tttcttggca
    22141 tttggcccat attctcaact tggatgaaaa tgatgccaac cgtgtggtct tcaatgaaat
    22201 caccaaggat gcagtcaaaa atgcttttaa agaacctcgt aagatcgata tggacttggt
    22261 cgatgcccaa caagctcgtc ggatcttgga ccgcttggta gggtattcga tttcgcctat
    22321 tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc gttcagtcca ttgcccttaa
    22381 actcatcatt gaccgtgaaa atgaaatcaa tgccttccag ccagaagaat actggacagt
    22441 tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct tccttctatg gagtagatgg
    22501 taaaaagatg aaactgacca gcaatgacga agtcaaggaa gtcttgtctc gtctgacgag
    22561 taaagacttt tcagtagatc aggtggataa gaaagagcgc aagcgcaatg ctcctttacc
    22621 ctataccact tcatctatgc agatggatgc tgccaataaa atcaatttcc gtactcgaaa
    22681 aaccatgatg gttgcccaac agctctatga aggaattaat atcggttctg gtgttcaagg
    22741 tttgattacc tatatgcgta ccgattcgac tcgtatcagt cctgtagcgc aaaatgaggc
    22801 ggcaagcttc attacggatc gttttggtag taagtattct aagcacggta gcaaggtcaa
    22861 aaacgcatca ggtgctcagg atgcccatga ggctattcgt ccgtcaagtg tctttaatac
    22921 accagaaagc atcgctaagt atctggacaa ggatcagctc aagctatata cccttatctg
    22981 gaatcgtttt gtggctagcc agatgacagc ggccgttttt gataccatgg ctgttaaatt
    23041 gtctcaaaag ggggttcaat ttgctgccaa tggtagtcag gttaagtttg atggttatct
    23101 tgccatttat aatgattctg acaagaataa gatgttaccg gacatggttg ttggaaatgt
    23161 ggtcaaacag gtcaatagca aaccagagca acatttcacc caaccgcctg cccgttattc
    23221 tgaagcaaca ctgattaaaa ccttggagga aaatggggtt ggacgtccat caacctacgc
    23281 gccaaccatt gaaaccattc agaaacgtta ttatgttcgc ctggcagcca aacgttttga
    23341 accgacagag ttgggagaaa ttgtcaataa gctcatcgtt gaatatttcc cagatatcgt
    23401 aaacgtgacc ttcacagctg aaatggaagg taaactggat gatgtcgaag ttggaaaaga
    23461 gcagtggcga cgggtcattg atgcctttta caaaccattc tctaaagaag ttgccaaggc
    23521 tgaagaagaa atggaaaaaa tccagattaa ggatgaacca gctggatttg actgtgaagt
    23581 gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt aaattctacg cttgtagcaa
    23641 tttcccagat tgccgtcata cccaagcaat cgtgaaagag attggtgttg agtgtccaag
    23701 ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt aatcgcctat tctatggttg
    23761 caatcgctat ccagaatgtg aatttacctc ttgggacaag cctgttggtc gtgactgtcc
    23821 aaaatgtggc aacttcctca tggagaaaaa agtccgtggt ggtggcaagc aggttgtttg
    23881 tagcaaaggc gactacgagg aagaaaagat taaataagag gaggggcccg aaagtaaatt
    23941 tcaggctcct tttggttaga acttgacaaa atacatcatt ttatgcgaaa ctagaagaag
    24001 attattttaa ctaggagaag ttatgcgtct tatctatctg ataattggtt ttttatcact
    24061 ggccttggct attgttgggg ttgttttacc cttgttgccg acaacgcctt tccttttgtt
    24121 gtctattgct tgtttctcca gaagttccaa gcgtttcgaa gactggcttt atcataccaa
    24181 gctctatcaa acatatgtag ctgattttcg cgagactaag tctattacgc gtgaacgaaa
    24241 gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt tctatttatt ttgcacctct
    24301 tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt atcacttatt atctcttcaa
    24361 ggtcattcca gacaaagaat agttaaaaca gtagttattt gccttgataa aattgaaagc
    24421 atattcataa caatatgata taataaattt gaagtaatat tcaaggagaa tcaaatgatt
    24481 tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag cgatgcaggc tggagctcgt
    24541 cggattgaac tctgtgataa tctagcagtt ggtgggacaa cacccagcta tggagtgact
    24601 aaggcagcgg ttgaactggc agctaactac gatacaacca tcatgaccat gattcggcca
    24661 cgtggtggtg actttgtcta taatgaccta gaaattgcta tcatgctaga agacattcgt
    24721 ttgactgctc aggctggaag tcaaggggtt gtatttggaa ctttaactgc tgataaaaag
    24781 ttggataagc ctaatctgga aaagttaatt gctgcatcaa aaggaatgga aattgtcttt
    24841 cacatggcct ttgatgaact aagtgatgaa gatcaactgg aagctattga ctggctcagt
    24901 caagccggtg tcactcgtat cctaactcgt gctggtgtgt ctggcgactc cttagaaaaa
    24961 cgttttgttc actatcacag aattttggag tacgctaaag gtaaaattga aattctacca
    25021 ggtgggggga ttgaccttga aaaccgtcaa acctttattg accaggtggg ggtaacacaa
    25081 ttgcatggta ctaaggttgt tttttaaaaa atagaaagga actgctagcc ttgggtagca
    25141 gttttcactt atgtttgaaa tttttaaatc ctatcaattt aatcaagaaa aggctcatga
    25201 ttatggtttt atagaaaata gcgaagtctg gacatatagt tgccagattt tgcaaggtga
    25261 ctttgtcatg actgtgtcca tcactgctga taatgtgaac tttcaagtct ttgaccaaga
    25321 gactggtgac ctctatcctc acgttcatat ggaaagcatg aggggaagtt ttgtcggaaa
    25381 tgtccgtgag gcttgtctgg agattcttta ccagattcgg aaggcttgtt ttgatgtgca
    25441 agattttatc tgtcatcaga ctaagcgtat catgactcaa gttcaggaaa agtatggaaa
    25501 ccagttggag tatctgtggg aaaaatcgcc tgatacagct gtattgcgcc atgaaggcaa
    25561 tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat aagctggaaa agggcagaga
    25621 aggacaagtg gaagcagtca acctcaagca tgaccaagta gctaatttgc tttcacaaaa
    25681 ggggatttat ccagccttcc atatgagcaa gcgctactgg attagtgtgt cccttgatga
    25741 tactttatca gatgaagaag tactggaatt gatagaaaaa agttggaact taacctctaa
    25801 aaaatgaaat attttaataa ttttcatgaa ctttcaatta gctgaatatt ctttactgaa
    25861 gaaattttca gaaaatatag gatttaccac accagaggaa tgtggtgcca tcttcaaata
    25921 cctgattgag aatgtcaaga cggatcgtca gatcatctat tcgcctcact gtcatgatga
    25981 cctcggaatg gcagtggcaa atagccttgc tgctgtcaag aatggtgcag gacgtgttga
    26041 agggactatc aatggtatta gggagcgagc tgaaaatgct gctttggaag aaattgcagt
    26101 ggctctcaat attcgccaag attactacca agtagaaacc agtattgtcc taaatgagac
    26161 catcaatacg tcagaaatgg tttctcgctt ctctggtatt ccagttccta aaaacaaagc
    26221 cgtcgttggt ggcaatacct tctcccacga atctggtatt caccaagatg gagtccttaa
    26281 aaatcctctc acttatgaga tcatcacacc tgaattggtt ggtgttaaga ttccgcttgg
    26341 aaaattatct ggtcgccatg cttttgttga gaaactgaga gaattggccc tagattttac
    26401 agaagaggat atcaaaccac tctttgctaa gttcaaggca ctggccgata agaagtaaga
    26461 aatcacagat gcagatactc gagctttggt agctggaacc atggttgaaa atccagaagg
    26521 cttccacttt gatgatttac aacttcaaac tcatgcagat aatgacattg aagcgctcgt
    26581 tagcctagcc aatatggatg gtgagaaagt cgaatttaat gcgacagggc aaggttccgt
    26641 tgaagcaatc tttaatgcta tcgataagtt ctttaaccaa tctgttcgtt tggtgtccta
    26701 cactatcgat gcggtaacag atggaatcga tacccaggat cgggttttgg tcactgttga
    26761 aaacagagat acagaaacca tctttaatgc agcagggctt gattttgatg tgttgaaggc
    26821 ttctgctatt gtctatataa acgctaatac ctttgttcaa aaagagaatg caggtgagat
    26881 gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc tatggcaaag
    26941 aaaatagtag ctctagcagg agacggaatt ggcccagaaa tcatggaggt tggtttagaa
    27001 gttctggagg ctctagctga aaaaacaggt tttgactatg agattgacag acgaccgttc
    27061 ggaggtgcag atattgatgc agcaggacct cccttacctg atgaaaccct taaggcaagt
    27121 agggaagcag atgctatcct actagcagct atcggtagtc ctcagtatga tggagcagtg
    27181 gttcgccctg aacagggcct gatggctctc cgtaaggaac tcaatcttta cgctaatatt
    27241 cgtcctgtaa aaatctttga cagtctcaag catttgtcac cactcaaact ggaacgaatt
    27301 gctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg ggatttactt tggagatcat
    27361 attcttgaag agcgcaatgc gcgtgatatc aacgactata gctatgagga agtggagcgg
    27421 attattcgca aagcctttga aattgcaaga aatcgcagaa aaatccttac tagtatcgat
    27481 aagcaaaatg ttctagcgac ctcaaaacta tggcggaaag tagctgagga agtcgcacag
    27541 gatttcccag atgtaacctt ggaacaccag ctggtagact cagctgctat gcttatgatt
    27601 accaatcctg ctaagtttga tgttattgta acggagaatc tttttggaga tattttatct
    27661 gatgaatcaa gcgtcttatc tggtacactt gaggttatgc catcagccag tcattctgaa
    27721 aatggaccaa gtctctatga acctattcac ggttcagcac ctgatattgc aggtcaagga
    27781 attgccaatc ctacttccat gattttatca gttgccatga tgttgagaga tagtttcgga
    27841 cgttatgagg atgcagagcg tatcaaacgt gctgttgaga caagtctggc ggcaggaatt
    27901 ttaacgagag atataggagg tcaggcttca acaaaggaaa tgacggaagc tattattgca
    27961 aggttatgaa gttagacgaa aaaattactc tagtcctttt gatttggaat gtcatcattt
    28021 tcttgattta tggcattgac aaattcaagg caagaagaag agcttggcgc atcccagaga
    28081 aaatcttact cattttagcc cttacttgtg gtggttttgg ggcctggtta gctggaatta
    28141 cttttcacca caagactcga aaatggtact ttaaaacagt ttggtttctt gggatggtga
    28201 ccacactagt agccttatat tttatttgga ggtaatggat ggcagggtct tcgagggaac
    28261 acgctgcttg ggctctagcg gactatggtt ttaaggtcgt gattgcagga tctttcggtg
    28321 acattcatta caataatgaa ctcaataatg gcctgttgcc aatcgttcag cctagagagg
    28381 ttagagagaa attagcccag ctaaaaccaa ccgaccaggt aactgtggac ttggaacaac
    28441 aaaaaatcat ctcaccagtt gaagaattca ccttcgagat agatagcgag tggaaacata
    28501 aactcctaaa tagtttggat gatatcggta ttaccttgca gtatgaagag ttgattgctg
    28561 cttatgaaaa acaacgacca gcctactggc aggattagaa aaaatagaaa aggaaatata
    28621 gtaaactgaa ataagatgta aacaaatgaa ttagagctta acatccattt ccagcaattt
    28681 tttagaaact acagtggact attctggatt caacacatta taaaattatg acaaaacaca
    28741 ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt gccctactaa
    28801 agttggttac attatcatga ccagcaacaa ggcaggactt gagcgtaagt tcgcagccaa
    28861 agaacgtaag cgtaacaaac caggtgttgt tctctgcggt agcatggatg aactttgcgc
    28921 tttagcgcaa ctcaacccag aaattgaagc attctactaa aaacattggg atgaagatat
    28981 tcttcttggt tgtatccttc cttggaaacc agaagccttt gaaaaactca aagcatacgg
    29041 ggatggccgt gaagaactta tgactgatgt acgtggtact agctgttttg ttatcaagtt
    29101 tggaaaagca ggtgaacaat tggctgccaa gctttgggaa gaaggtaaaa tggtctacgc
    29161 ctcatatgct tcaatgacaa aacgattgaa actcgctatg agagcaaggt gtaatggtgt
    29221 ctatggtcga taaggacggc aaactcatcc cagaacaagg aggagcacgt tcaacctcac
    29281 cagcaccagt tgtgatccgt aaagggcttg acattgataa aatcatgatg cacctgtcag
    29341 atacttttaa ctcatgggac taccgtcagg ttgagtatta ttaggataga gaagaagtct
    29401 agtgttaagg acattacagc tcataatact aggctttttt atagaaattc ttttcttttt
    29461 ctataggata tggtattcta tgtagaaaat atatgttaat aagtaatgcc aatatttaaa
    29521 catcattagt aaaaggagtt agattgatga ataaaagaaa agttagttta gaagattttt
    29581 ataaatggta tagtctaaat aaagaagagt tattaaataa ggcaactgtt ggtgaaaagt
    29641 ttaatgataa attaaaagaa gagtttctcc aggaatggcc tttggatagg attttaacaa
    29701 tgtcaatcga tgaatatgta ataggaaagg gacagcaaaa taagtcttta tgctacgctc
    29761 ttgagaaggg aaaatacaaa aatctatttc ttggaatttc tggtggctca gcttcaaaat
    29821 ttggtattta ttggaataaa aaaa
//
LOCUS       DAVHSL010000028        28588 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000028 DAVHSL010000000
VERSION     DAVHSL010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.028"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..307
                     /locus_tag="VVR39_001223"
     CDS             <1..307
                     /locus_tag="VVR39_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HEU6030716.1"
                     /translation="DVYNFAHYLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAH
                     YVYSEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            815..2308
                     /locus_tag="VVR39_001224"
     CDS             815..2308
                     /locus_tag="VVR39_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6030717.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKI
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            2321..3430
                     /locus_tag="VVR39_001225"
     CDS             2321..3430
                     /locus_tag="VVR39_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6030718.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            3460..6792
                     /locus_tag="VVR39_001226"
     CDS             3460..6792
                     /locus_tag="VVR39_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6030719.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVTYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYFRADPRDGE
                     GRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLNELDFRV
                     RMVLDTVYSYRKLESWQNLTTVTSETIQKNLSPLLFDEDKEDEMARRFDLWLLHIQLG
                     QLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLSDLEKIR
                     LAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLD
                     EESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRES
                     ANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQ
                     LPVLRNIVQIIELINNRAGEAA"
     gene            7036..7137
                     /locus_tag="VVR39_001227"
                     /pseudo
     CDS             7036..7137
                     /locus_tag="VVR39_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7334..7804)
                     /locus_tag="VVR39_001228"
     CDS             complement(7334..7804)
                     /locus_tag="VVR39_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6030720.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(7821..10094)
                     /locus_tag="VVR39_001229"
     CDS             complement(7821..10094)
                     /locus_tag="VVR39_001229"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU6030721.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            10441..13542
                     /locus_tag="VVR39_001230"
     CDS             10441..13542
                     /locus_tag="VVR39_001230"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU6030722.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDLFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVRKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSEQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            13624..14631
                     /gene="pfkA"
                     /locus_tag="VVR39_001231"
     CDS             13624..14631
                     /gene="pfkA"
                     /locus_tag="VVR39_001231"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU6030723.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            14690..16195
                     /gene="pyk"
                     /locus_tag="VVR39_001232"
     CDS             14690..16195
                     /gene="pyk"
                     /locus_tag="VVR39_001232"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU6030724.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            17879..18751
                     /locus_tag="VVR39_001233"
     CDS             17879..18751
                     /locus_tag="VVR39_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU6030725.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            18764..18928
                     /locus_tag="VVR39_001234"
     CDS             18764..18928
                     /locus_tag="VVR39_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030726.1"
                     /translation="MTVILGFLFLFLMSWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(18897..19241)
                     /locus_tag="VVR39_001235"
                     /pseudo
     CDS             complement(18897..19241)
                     /locus_tag="VVR39_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            19384..19695
                     /locus_tag="VVR39_001236"
     CDS             19384..19695
                     /locus_tag="VVR39_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030727.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            19699..20307
                     /locus_tag="VVR39_001237"
     CDS             19699..20307
                     /locus_tag="VVR39_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6030728.1"
                     /translation="MKKYFISGLGSNAYHSEEESICLIGHSLGGDLARYLASEFEEVK
                     KLILLDGGYLDLDKILPLDTELEETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKA
                     VRQSYHWNVEYNRYELAINYENIEAILRLRRKIQAFKREVGDTLFISPRYPNEATWRE
                     EALKELPDYFDTIFLENFGHELYTQAPKEIASLMNEWLAYFL"
     gene            complement(20437..21252)
                     /locus_tag="VVR39_001238"
     CDS             complement(20437..21252)
                     /locus_tag="VVR39_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU6030729.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(21249..22154)
                     /locus_tag="VVR39_001239"
     CDS             complement(21249..22154)
                     /locus_tag="VVR39_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU6030730.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            22544..23860
                     /locus_tag="VVR39_001240"
     CDS             22544..23860
                     /locus_tag="VVR39_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEU6030731.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIINENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPWGD
                     NWLTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQFDINNLIWRLYIH
                     SKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLENYDIERAKKQYIQ
                     ELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTIISNNCVGGLIYKQ
                     LGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWTHEVYPLGHLGDI
                     DIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNKMDNLPYSNKLIL
                     VNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL"
     gene            23962..26091
                     /locus_tag="VVR39_001241"
     CDS             23962..26091
                     /locus_tag="VVR39_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU6030732.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHISRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            26078..26527
                     /locus_tag="VVR39_001242"
     CDS             26078..26527
                     /locus_tag="VVR39_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU6030733.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            26586..26858
                     /locus_tag="VVR39_001243"
     CDS             26586..26858
                     /locus_tag="VVR39_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6030734.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(27212..27403)
                     /locus_tag="VVR39_001244"
     CDS             complement(27212..27403)
                     /locus_tag="VVR39_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030735.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            27831..>28588
                     /locus_tag="VVR39_001245"
     CDS             27831..>28588
                     /locus_tag="VVR39_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030736.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVPHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
BASE COUNT         9076 a         4862 c         5979 g         8671 t
ORIGIN      
        1 tgatgtttat aactttgctc attacttgga cctttatcgt ggctatgcag ctattgtcgc
       61 aggagaggag ttcccggcgt cagactttga aactcagtat tgtttggcta cttctcgccg
      121 tgcaaatgct cactatgttt attcagaaga ggatttgctt gccaaatata gccagcagtt
      181 caaggttaaa aaagtcatgc cagctgcctt cgcggaactt caaggagatt acctgtatat
      241 gctgaccact ccgagtcgac aagaaatgga gcagatgatt gcagatttcg gacaacgtca
      301 agaataagaa ctatcggatt aaggaaatta actcccttaa tccttttgtt ttgtctgata
      361 aaaaataaga gcatcccaac aaggtagcta tcataaaact tgttcgataa ctatttgaag
      421 caggattagg tggtcagaaa ttgaatttta atatttcaat tgagtcatag tattgtgttt
      481 gcgtatcctt aaatcagcta aaaggatcca tgacgacacc tatacgatat agttttcaag
      541 ataccaaaca agtctattaa tactcaatga aaatcaaaga gcaaactagg aagctagccg
      601 caggtttctc aaaacactgt tttgaggttg tggatagaac tgacagagtc agtatcatat
      661 acctacggca aggtgaagct gacgtggttt gaagagattt tcgaagagta taaaatattc
      721 aggtgacgca tagatatagt taattgaagc tttgtttgaa atctgataaa ataatgatat
      781 tactaagttt taaaaactaa agaaaaggga agatatgatt acaggcgaat taaaaaataa
      841 aatcgatcag ctgtgggaaa ttctttggac agaaggaaac gcaaatcctt taacaaatat
      901 tgaacagttg acttatctct tatttatgaa agatttggat agtgtcgagc ttggacgtga
      961 aagtgatgct gaatttctag ggattcctta tgagggagtt tttccaaaag ataaacctga
     1021 ataccgttgg tcaactttta aaaatatagg agatgctcag gaagtttatc gtttaatgac
     1081 tcaggagatt tttccgttta ttaaaaatct caagggggat acagatgata cagccttttc
     1141 acgatatatg cgagaagcta tttttcaaat aaataaacct gctacgcttc aaaaggcaat
     1201 ttctatctta gatgtttttc caactagggg attagatgta gattttgata atgacaaaca
     1261 aagtattact gatatcggag atatctatga atatctgtta tcaaaattgt cgaccgcagg
     1321 taaaaatgga cagttccgta cacctcgtca catcatcgat atgatggttg agttgatgca
     1381 accgactatc aaagatatca tctcagatcc cgctatgggt tctgctggct tcttagtatc
     1441 tgctagccgt tacttaaagc gtaagaaaga tgaatgggaa accaatacag ataatatcaa
     1501 tcattttcat aatcagatgt ttcatggaaa tgatacggat acgactatgt tgagacttgg
     1561 ggcgatgaac atgatgctac atggagtaga aaatccacaa atcagttacc ttgactcgct
     1621 gtctcaagat aatgaagaag ccgataaata tactttggtt ttagcaaatc ctccttttaa
     1681 gggctcactt gactacaatt caacctctaa tgaccttctt gcaaccgtaa aaaccaaaaa
     1741 aacagaatta ctctttcttt ctcttttctt gcgaacttta aaaccaggtg gacgagcagc
     1801 agttatcgta cctgatggtg tcctttttgg ttcgtctaaa gctcataaag gaattcgtca
     1861 ggaaattgta gagaatcata agcttgatgc tgtaatctca atgcctagtg gtgtgttcaa
     1921 gccttatgct ggagtttcaa ctgccattct catctttaca aaaactggta atggtggtac
     1981 tgacaaaatc tggttttacg atatgaaagc ggatggttta agtttggatg ataagcgaca
     2041 accgattagc gacaatgata ttccagatat tatcgaacgc tttcatcatc ttgaaaaaga
     2101 agcagaacgt cagagaacgg atcaatcttt ctttgttcca gttgctgaga taaaggaaaa
     2161 tgattatgat ttgtctatca ataaatataa agagattgag tatgaaaaag ttgagtatga
     2221 accaacagaa gtcatattaa agaaaatcaa tgatttagaa aaagaaattc aagctggctt
     2281 ggctgaattg gaaaaattac tcaagtaggg aggtggctgt atgaaaaaag tgaagttggg
     2341 ggaagtctta tctctaaaaa aaggcaagaa agccactgta cttgctgaac aaacaactct
     2401 aagccaacgt tatattcaaa tagatgattt aagaaataat aataatttaa aattcactga
     2461 aagtttaaat atgactgaag cactcccaga tgatattctg atagcatggg atggagctaa
     2521 tgcaggaaca gttggttatg gattatcggg agctgttggt agtacaatta cggtcttaaa
     2581 aaagaatgag cgatacaaag aaaaaattat atcagattac ttgggagtct ttttggaaag
     2641 taaatcgcag tatttacgag atcattcaac aggtgcaaca attcctcatt taaacaagaa
     2701 tatattactt gatttacaat tagaattgct aggtatcgaa gaacaagaga acattatctg
     2761 tattcttaat acgattaaaa ggcttattac taaaagaaaa ttgcagttag atgaactaaa
     2821 cttgctcgtc aaatcccgat ttaacgagat gtttggggaa aataaaatat ttgaaagcat
     2881 tgataactta tttgatatta tagatggtga taggggcaaa aattatccta aatcagatga
     2941 gttgtttagt gaggagtact gtttattttt aaatacaaag aatgttacta aaaacggatt
     3001 ttcattcgat acaaagcaat ttatcactaa aacaaaggat aaattacttc gaaaaggcaa
     3061 acttgagcgt tatgatatag tcttgacaac aagaggtact gttggaaatg tagcgtacta
     3121 cgatgaatta ataaaatata aacatttacg tataaattca ggtatggtaa tattacgtcc
     3181 caagacacca aatctaaatc agaaatttat tatccatgtt ttaaggaata ataattatag
     3241 tcgagtgata tcaggaagtg ctcagcctca gttaccaatt acaaaattaa aaaaaatact
     3301 tctccccctc cccccactag ccctccaaaa tgagttcgca gactttgtag tccaggtcga
     3361 caaatcacaa tttgcttgtg agatagctat aaaagtgtgg agaaatagct tgaaatttag
     3421 tataatatag ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt
     3481 ttaaaaaatg acgaatatga atctttttca aaaccttgca ttgaagctga aaatatgatt
     3541 gctacatcaa ctgtggctac tgcctttatg gcgcgtcgtg ctttagagca ggctgtccat
     3601 tggatatata gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta
     3661 gtatgggatg atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg
     3721 ttgattcggt ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt
     3781 ttagctttac atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgaa
     3841 tttgtggagc gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga
     3901 gaaactccac aatctatgat aaagttacaa gacagtttac cagaactgcc tgattttcat
     3961 gaacagatgg ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact
     4021 gcagcgcaac ggcaagatgt gcctttccat attgatcaat tatctgaggc agagacaaga
     4081 aagctcttta ttgatatcga tctccgttta gcaggatgga tatttgaaga aaactgtcgt
     4141 gttgagatag ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactatgta
     4201 ctttatggta aaaatgggaa aattttagcg attgtggagg ctaaaaaagc ctctgtcaat
     4261 ccagaagtag gggaagtaca ggtcaaagaa tatgctgaag ctttggagaa acatatcggc
     4321 tatcagccaa tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac
     4381 cgccgccaga ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt
     4441 catcttcaaa aaccacttga ggatatttct agtaaaatta gggacgatat ttccgggcgt
     4501 cactaccaaa aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag
     4561 gcacttttgg ttatggcaac tggggctggg aaaactcgta cagcagtttc tctagttgat
     4621 atcttatcac gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg
     4681 gttaagcaag cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc
     4741 ttagaagata aagaaggagc tcaatcaagt cgcatggtct tttcaactta tccgaccatg
     4801 attggagcga ttagtggtca agaagaagta aatcaacgcc ctttcactgt tgggcatttt
     4861 gaccttatca taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt
     4921 gattattttg atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa
     4981 aacacctatg gattctttaa tttggagaat ggggttccaa catatgcata tgatttggaa
     5041 gaggctgtta aagacggata tttagtaacc tatcattcta tcgaaaccaa actgaaacta
     5101 cctacggatg gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc
     5161 aaatttgaag acgatagctg tgaaaaagat attgatggga gtgtatttaa ttcctttgtt
     5221 ttcaataaaa gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca
     5281 gcctcgggtg atgaaattgg taaaactatt atttttgcta aaaatcatga tcatgcggaa
     5341 tatatcagag gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg
     5401 attgattata gtattaagca ttatcagacc ttgattgatg attttaaaat taaggagaag
     5461 tatcctcaaa ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt
     5521 gttaatttag tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt
     5581 cgaggaaccc gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg
     5641 gtatttgatt attttcgtgc agatccaaga gatggagagg gtcgtcacat tgtttcgttg
     5701 actcagcgtt tatttaatat caaagtggac ttgattcgag aacttcaggg actccaatac
     5761 caagaagatc agtttgcgag agcataccgt cagcagcttg tctcggaact tcaaggtcgt
     5821 atagagagct taaatgagtt ggacttcagg gttcgtatgg ttttagatac agtttatagc
     5881 tataggaaat tggaaagttg gcagaatcta actactgtta caagtgaaac cattcaaaaa
     5941 aatctctctc cgcttttatt tgatgaagat aaagaagatg agatggccag gagatttgat
     6001 ttgtggttgc ttcatattca gttggggcaa ctgacagcta aatcttccac tgttcatatt
     6061 tcccaagtga tgaagacggc tagagctctt tctgctattg gcaatatccc gcaggttttt
     6121 gagcaggctg aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg
     6181 tctgatttgg aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca
     6241 gaccgtaaac cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc
     6301 acagcatttt tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg
     6361 aaaactcatc tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct
     6421 gatgatatgc ttgcacttga aaaattgctc tgggaaaaat taggtagtaa agcagactac
     6481 caaagtcatt atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat
     6541 agagagtctg ccaatcgtat tttttctaaa tttttgtcgg atgagaatct taatgccagg
     6601 cagatttcat ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg
     6661 aaagtgttaa cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac
     6721 caactaccag tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga
     6781 gaagcggctt aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt
     6841 agaaatttat gctatatatg agaagtttta ttaggaagaa tgtcatcgtt tttctagaat
     6901 acagtatcag ttgttaagtg gctgataaat ttcaaagtag atacttgtac cacgatgttt
     6961 gttgatcgag ttattaacaa aagagctact ttgattttaa agaaatagaa aacaaaaagc
     7021 cgagcaagaa ttcaattgca ggagaaaatg aaataatact caatgaaaat caaagagcaa
     7081 actaggaaac tagctgcagg ctgctcaaaa cactgttttg aggttgtaga tgaaactgac
     7141 gaagtcagta accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa
     7201 gagtataaat tttcctagga taaagcaaaa cgcatagtat caagggtttt caacacttga
     7261 tactatgcgt tttctgatgt taaagacttt ctaccagttt tttttaagca taattgttag
     7321 ttgtagtcat ttattattct tcaaagaaaa atggtggggc gaattttttc agttcttcaa
     7381 agcacttttg agcagtatct gcatcttcac agatgataag acagacatca ttaccacaaa
     7441 gggtagcgat agcgtcaggg aagctcaaag tatcaatgat agaaccaaag gattgagcca
     7501 gtccaggaag ggtttttagt aggacttggt gttgaactgg gcgcatccag acaagggcgt
     7561 cttccatgta gagttcgaga cgtttttccc attttgagat ggaaccattg ttaagaacat
     7621 aataagcgct atcttcttcg cggacttttg ataggttcat atttttgatg tcgcgtgaga
     7681 gggttgcctg ggttacttga atgtcgttct tagcaagaag ggcttgcaac tcagcctgtg
     7741 tatgaatctt gttttttgtg ataagagcgc gtataagttg gtggcggtgt tctgatttat
     7801 tcataataat gtaactcctt ttagcaaggt aaggtaagca tggactgagc gaggtcgaca
     7861 gtcaagtggt agtctgtatt gtcacggatg gtgatttcaa agtcagtagt atagaggact
     7921 aaacggagag tgtctccttc ttttagcttg taaatagttg gctgcagttc aaattgaacg
     7981 tccatccatt catctgcagt aatatcctct actaacagta aatcatttct attttgtaaa
     8041 ttaaggtaac cttttgtcac gactcgttgt gcctctggtc taaatggcaa ttcacagaga
     8101 ttttccaaca tgtgatagcg accgttgtca atggttctag cacttaaaat agctggataa
     8161 ggttgtaggt atttcttttg cccaaattct agcagttggg cagataagag ccccttgttt
     8221 gtactggatt tgatacgaag attgagctga gcgcgaccgt ttaggtggag atctttagtc
     8281 acaggaaggt taatagtaat ctgattggct ttcccttgat agagctctgt attgaaggtt
     8341 tggtatgtct taccatagcg ctcaaaatcc ttatctgggt actggttttg aatagcttgc
     8401 tcttcttgac caagtgagaa ggtttcacag ttttcttgcc caccgaagtt atcaagtgat
     8461 aaccaagtct gtggagctgt attgtcctgc cagataacag taggaagttg aaagtctgtt
     8521 tcctgtccta gtaatttctt ggtcaataag gcatttatgg actcacggaa gtcaattgat
     8581 tgccaattgt tcatgtaaac atgggcacca ttatggaaaa agagatgctt gtgtatatga
     8641 gtaggaagag catggaacat ctggtaaaca tgaagtggtt tgacattcca atcctgagaa
     8701 ccatgagtaa agacaacctc tgcctttact ttatgggcat tgagcagata attgcggtca
     8761 tgccaaaact gattgtagtc cccagttttt cggtctagct gagctttcac tttttctaag
     8821 tcagcttggt gagcttcatt gccacggata tagtcgccag ctaagagatt acgagaatag
     8881 gttaactcag caagggagtc aaagtcctca cctggataac cacctgggct agtcaccaga
     8941 ccgttttcac ggtagtagtt gtaccatgat gaaattcctg cctcggcaat gataacttct
     9001 aaaccatcga ctcctgtagt cgcaagacca ttggacatgg tacctagata ggaaagtcct
     9061 gttgtagcaa cttttccgtt tgaccaatca gccttgactt gacgctggcg cgtgtgatca
     9121 gtaaaggcac ggcaacggcc gttaagccaa tcgatgacat ttttataagc ctcgatttgc
     9181 tggtagtctc cattagtcat gaaacctgtc gagtctttgg taccaacacc tgagacatag
     9241 agattggcaa agcctctcgg aaggaagtag tcgtttagtg tatagctaga gttgatgtga
     9301 gttagctttt cctcagcctc tgctataagc tcagctttac cttggggttg gacgagattt
     9361 agttgaggtt tctctagctc aatcttgtga ggaagcttaa cctcaagctc gccctccatc
     9421 ttgtagagag ccttgtcact agccttgtca ttggttccct gatgataagg gctggctgtc
     9481 atgatggcag ggatttttcc atcaaaacga gggcgaataa tgctaacctt tactaggtct
     9541 gatagccctt tttggtcagt atcgacacga gactcaacgt aaacgacttc acgaatgaca
     9601 tcctggttag aaaaagtagc caaactcttg ccgttaaagt agtggtagtc attatcctcc
     9661 ggaataagac catcactaac aagttggtct ataagagtat ttcctttttt ggtgcgagta
     9721 ttgagtaact gatagagatt ttcaatcaag tcaccatata taatgggaaa tccagtttct
     9781 ttacgaaaaa cgtcactatc ttcgaagtca accaaataag aaaagcctaa aagttgaaaa
     9841 gcaacagtat aaaaaatatc tgctgtcagt tcatcttctg attgaaaaaa tgtcagcagg
     9901 tctgtttttt tatcagctgc taggatagaa agtgggtagt tggtgtcttg ataagtgaaa
     9961 aagaaacgac gtaaaaaggt ttcaagtgag tctttgtgat tggctgtatt ttgtaaatca
    10021 aagccacatt tttttagttc agataagaca ttttcttttg gaaaattgat ataactatat
    10081 tgattaaaac gcatagaacc tccatataga atgacagtta aggttattat atcaaaaaaa
    10141 aagcagaaag ggaattgtta acttcaaaag gaaataatcc aataaaaatg aataaagtac
    10201 taaattcaat atagagaaca gagtaacaat aagaataaat agatagggta taaaagttct
    10261 aggagattta tattatatgc tttctatttt tatatacaat atagtataaa tataaaaatg
    10321 atgacaaaaa tacaaatgaa tagaaaataa attagtaagc tgatgaaatg tttctcaaga
    10381 gaagccattt ataggtgaaa atggtataat atagtgagaa ggatagagga gaagtgtaaa
    10441 ttgatcgcac aactagatac aaaaacagtc tatagtttta tggaaagcgt catttcgatc
    10501 gaaaagtatg tgagagcagc taaagaatac ggctacactc atttggctat gatggatatt
    10561 gacaatcttt atggcgcttt cgactttcta gagattacaa aaaaatacgg cattcatcct
    10621 ttgctagggc ttgaaatgac agtgtttgta gatgatcagg aagtgaattt gcgcttttta
    10681 gctctatcta gtgtgggcta tcagcagttg atgaagcttt cgacagccaa gatgcagggg
    10741 gagaaaactt ggtcagtcct gtcccagtac ctggaggata tcgcggtcat tgtgccttat
    10801 tttgatagag ttgagtcgtt agaactaggc tgtgattact atataggggt ttatccagaa
    10861 acactagcaa gcgaatttca tcatcctatc ttacctcttt atcgggtcaa cgcttttgaa
    10921 agcagggata gagaagttct tcaagtttta acagcgatta aagaaaatct accgctcaga
    10981 gaagttccct tgcgttcgag acaagatgtc tttatatcag caagttcttt agagaaacta
    11041 ttccaagagc gttttccgca agctttggac aatttagaaa agcttatttc aggcatttct
    11101 tacgacttgg atactagtct gaaactgcct cgttttaatc cagctagacc agcagtagag
    11161 gagttgagag agcgtgctga actggggctt gttcagaagg ggttgactag taaagaatat
    11221 caagatagac tagaccaaga attgtctgtt attcatgata tgggctttga tgattatttc
    11281 ttggttgttt gggatttgtt gcgttttgga cgatcgaatg gctattatat gggaatggga
    11341 aggggttctg cagtaggcag tttggtttct tatgccttag acatcacggg gattgaccca
    11401 gtagagaaaa atctgatttt tgaacgcttt cttaatcgtg aacgctatac catgcctgat
    11461 attgatattg atatcccaga tatttatcgt ccagatttta tcagatatgt tggtaataaa
    11521 tatggtagta aacatgcggc acaaatcgtt actttttcaa cctttggagc caagcaagct
    11581 cttcgagatg tcttgaaacg ctttggtgtg ccagagtatg aattatctgc aattactaag
    11641 aaaatcagtt ttcgtgacaa tcttaagtcg gcctatgagg gcaatctcca gtttcgtcag
    11701 caaatcaata gtaagttaga ataccaaaaa gcttttgaga ttgcttgcaa gatagagggc
    11761 tatccaaggc aaacctctgt ccatgcggct ggtgttgtaa ttagtgacca agatttaacc
    11821 aactacattc ctctaaagta tggtgatgaa attccactga ctcagtatga tgctcatgga
    11881 gttgaggcta gcggactttt gaagatggac tttctgggac tacgaaattt gacctttgtc
    11941 cagaagatgc aagagttgct tgctgaaata gaaggtattc atctgaaaat tgaagaaatc
    12001 gatttagaag acaaagaaac gttagcttta tttgcctctg gtaatacaaa aggtatcttt
    12061 caatttgagc aaccaggtgc cattcgtctg cttaagcgtg tgcaaccagt ctgttttgaa
    12121 gatgtcgtcg cgactacttc tctaaatcga ccgggtgcta gtgactatat caataatttt
    12181 gtggcaagaa agcatgggca ggaagaagtg actgttctgg atccagtact ggaggatatt
    12241 ttggctccaa cctacggcat aatgctctat caggagcagg ttatgcaggt tgcccagcga
    12301 cttgccggat ttagtcttgg gaaagccgat attttgcgtc gggctatggg gaaaaaggat
    12361 gcctctgcca tgcatgagat gagggcttcc tttattcaag gttcattaga agctggtcat
    12421 actgtggaaa aagcagagca ggtctttgat gttatggaga agtttgcagg ctatggtttt
    12481 aacaggtcac acgcctatgc ctactcagcc ttggccttcc agttggctta ttttaaaaca
    12541 cattatccag ccatatttta tcagattatg ttgaattctg ccaacagtga ttatgtaaca
    12601 gatgccttag aagcaggttt tgaagtagcc ccattgtcca tcaatactat tccctatcac
    12661 gataaaattg ccaacaagtc tatctatata ggtttgaaat cgattaaggg gctcagcaag
    12721 gacttggcgc tttggattat tgaacataga ccttattcta atattgaaga ttttatagct
    12781 aaattacctg agaattatct gaaacttcct ctgctagaac ctttggtaaa agttggcctt
    12841 tttgatttat ttgaaaaaaa tcgtcaaaaa gtatttaata acttagctaa tctatttgaa
    12901 tttgtgaaag agttgggaag tttgtttgga gatgctattt atagttggca ggaatcggaa
    12961 gattggacgg aacaagaaaa attttatatg gaacaagagc ttttagggat aggtgtcagc
    13021 aaacatccac tacaagctat tgcaagtaag gctatttacc cgattacccc aatcggaaat
    13081 ttgtcagaaa atagctatgc tattattttg gttgaagttc ggaaaataaa agtgattcgt
    13141 accaaaaagg gtgaaaatat ggccttctta caggcagatg atagtaagaa aaaattggat
    13201 gtcactctct tttcagactt atatcgtcag gttggacagg aaataaaaga gggagccttc
    13261 tactatgtaa aaggaaaaat acaatcacgt gatggccgtc tgcaaatgat tgcacaagaa
    13321 ataagagaag cagttgctga acgcttttgg attcaggtta aaaatcatga ctcggagcaa
    13381 gagatgtcac gtattttaga ccagtataaa ggcccaatcc cagtcatcat ccggtatgaa
    13441 gaggaacaga aaaccatcgt ttctccccat cattttgtag ctaaatctga tgaattagag
    13501 gcgaaattga atggaatagt tatgaaaacg atttatcgct aaaattacgg aaaatagaag
    13561 aattttcaac gtaaatgtgg tataatcagt aagaatgtta aaagaaaaag gagcataacc
    13621 aatatgaaac gtattgctgt tttgactagt ggtggagacg cccctggtat gaacgctgcc
    13681 atccgtgcag ttgttcgtca agcaatttca gaaggaatgg aagtgtttgg tatctatgac
    13741 ggatatgctg gtatggttgc cggtgaaatt catcccctag atgcagcttc agtaggagac
    13801 atcatttctc gtggtggtac ttttcttcac tcagctcgtt atccagagtt cgctcaactt
    13861 gaagggcaac ttaaagggat tgagcaattg aaaaaacacg gaattgaagg tgtagttgtt
    13921 atcggtggtg acggatctta ccacggcgct atgcgtttga ctgaacatgg cttcccagct
    13981 attggtcttc caggtacaat cgataacgat atcgttggta ctgactttac aatcggtttt
    14041 gacacagcgg ttactactgc catggacgct attgataaga ttcgtgatac atcatcaagt
    14101 caccgtcgta cttttgtaat cgaagttatg ggacgtaacg ctggtgatat cgctctttgg
    14161 gctggtattg caactggtgc tgatgaaatc atcatccctg aagcagactt caagatggaa
    14221 gatatcgtag caagcatcaa agctggttat gaatgtggta aaaaacacaa tatcatcgtc
    14281 ttagctgaag gtgtgatgtc agcggctgaa tttggtcaaa aacttaaaga agctggagat
    14341 acaagcgacc ttcgtgtaac agaacttgga catattcaac gtggtggttc tccaactgcg
    14401 cgtgaccgtg ttttggcgtc acgtatgggt gcacatgctg ttaaacttct taaagaaggt
    14461 atcggtggtg ttgcggttgg tattcgtaac gaaaaaatgg ttgaaaatcc aattcttggt
    14521 actgcagaag aaggggcatt gtttagcctt actgcagaag gtaagattgt ggttaacaac
    14581 ccacacaaag ccgatattga gctatctagc ttgaataaga gcttgtcata atttacaatt
    14641 tagttaataa gaccaaaaag gtcatatata taaaggagtc acaaaaatca tgaacaaacg
    14701 tgtaaaaatc gttgcaactt tgggtcctgc ggtagaaatc cgtggtggta aaaaattcgg
    14761 tgaggacgga tactggggtg aaaaacttga tgttgaagct tcagctaaaa acattgctaa
    14821 attgattgaa gctggtgcta acacattccg attcaacttc tcacacggcg accaccaaga
    14881 acaaggtgag cgtatggcaa ctgttaaact tgcggaaaaa attgcaggta aaaaagttgg
    14941 tttccttctt gatacaaaag gacctgaaat ccgtacagaa ttgttcgaag gtgaagctaa
    15001 agaatattca tacaaaactg gtgaaaaaat tcgtgttgca actaaacaag gaatcaaatc
    15061 aactcgtgaa gtgattgcgt tgaacgttgc tggtgctctt gatatctatg atgatgttga
    15121 agttggtcgt caagttttgg ttgacgatgg taaacttggt cttcgtgtgg ttgctaaaga
    15181 tgatgaaact cgtgaatttg aagttgaagt tgaaaacgat ggtatcatcg ctaaacaaaa
    15241 aggtgtgaac atccctaaca ctaaaattcc tttcccagct cttgctgaac gcgataacga
    15301 cgatatccgt ttcggtcttg aacaaggtat caacttcatc gcaatttcat tcgtacgtac
    15361 tgcaaaagat gtgaacgaag ttcgtgcaat ctgtgaagaa actggaaacg gacatgttca
    15421 attgttcgct aaaatcgaaa accaacaagg tatcgataac ttagacgaaa tcatcgaagc
    15481 agctgatggt attatgattg ctcgtggtga tatgggtatc gaagtaccgt tcgaaatggt
    15541 tccagtttat caaaaaatga ttatcaagaa agtcaatgct gcaggtaaag ttgttatcac
    15601 tgcaacaaac atgcttgaaa caatgactga aaaaccacgt gcaactcgtt cagaagtatc
    15661 agacgtattc aacgctgtta tcgacggaac tgacgctaca atgctgtcag gcgagtctgc
    15721 aaacggtaaa tacccactcg agtcagtaac tacaatggct acaatcgaca agaacgctca
    15781 agctcttctt aatgaatacg gacgtcttga ttcagattca tttgagcgta actctaagac
    15841 agaagtaatg gcttctgctg ttaaagatgc tactagctca atggatatca aattggttgt
    15901 aactcttact aagacaggtc atactgcacg tttgatttct aaataccgtc caaatgctga
    15961 catcttagca ttgacatttg acgaattgac agaacgtggc ttgatgttga actggggtgt
    16021 tatcccaatg ttgacagatg ctccatcttc aactgacgat atgttcgaaa tcgctgaacg
    16081 taaagcggta gaagcaggtc tcgttgagtc aggcgatgat atcgttatcg ttgctggtgt
    16141 gccagtagga gaagctgttc gcacaaacac aatgcgtatc cgcacagtac gttaagaaaa
    16201 atataaaaac ctatcatatc cagctttaga gcttgtgtga taggcttttt gtatagaggg
    16261 taagaaatag gcaaaacttt cataatggat tgatactctt cgaaaatcaa attcaaacca
    16321 cgtcagcgtc gccttaccgt atatatgtta ctgacttcgt cagttctatc tacaacctca
    16381 aagcagtgct ttgagcaacc tgcggctagc ttcctagttt gctctttgat tttcattgag
    16441 tatgaaataa gatatgcaca aattgattag gaaattcaaa tgaatttcta caaatgtttt
    16501 agcaatcgta atgtacttgt ctagattcga tctgatatat tttcgattta atgatatggt
    16561 atttaaaacc tccaaagtag cttgctccat tcttttactt acgtgagtgt agatgttatt
    16621 tactgtttta gcgtttttgt gttccactct aaccattata gcattcttct cagctagtgt
    16681 actaaggagt gtgtgcctga aaatatggga actaaggggc tggtttatcg gtttctctag
    16741 tttagtattt gccttttgca aagtgatgtt aaatgccttt ctctaaattt acatatcact
    16801 attgtttaac aaaatctaat ctactttagg tcacttattc tttttttgaa atgtagaatg
    16861 aactttttca aagtttttcg aatcttttaa aatctgtttg ttttatatcg ccattctccc
    16921 ccttttttaa ttctccctat atagcctgac aactttcccg atggtattat agtcaatctg
    16981 tggggtattc ttgataaata ggtagtcgct gtttcttatc tttggctcca tggacttgct
    17041 gacgacataa gcgattgggt cgtagtcgtc tgggataatg gaaactccat atctaaatcg
    17101 ttgtcctgca tcgagcggct atctgcagag ataaactacc taacacgaga gtaagtagtc
    17161 tgtctgtagt cgtccagtct gatgattttt acgatacttc gtttttctgc tcatacagtt
    17221 gcctctcggc ataggtcagg actttacctt gtctgggtgg tacccgttgg tcgtagatag
    17281 attggatatc gctaggagaa tccttttgaa ctggaggaaa gagggcatca atcaagctac
    17341 tgaatacttt aactaagtca aatatagtat ttttcttagt agacctaacc cttttttcat
    17401 aatttctaat ggtgttttta cttataccta tcttagtacc caattcttat tgagtccaac
    17461 tattactagt ctatattgtt ttatagttga ttgagtttgg aatagtacgc tgtagctgct
    17521 aaaacatttc taggaattaa tttgcctttc ctaatagagt tgttcatatc ttatttcaat
    17581 ctattatgtt tttcacctct aacaatcgca atctcttctt tatctatgaa tgaaatcgat
    17641 ttctattttt gtaagtaaag cataacacga aatccacgaa aatgaaaacc tttgttgtgt
    17701 tttcgtaaaa aatttgttga cagagcacgg aacgcctact ataattaaat caagcttaag
    17761 gaaataacaa aaaaacaaat cggagggaaa gacgatgaac acattaaatg agaaagtaat
    17821 caatatctgt aaagcagtag ttaaagaaac tttaatccaa gacatttagg agaaagaaat
    17881 gaagaaatca agaaaattag ccacattagg aatctgttca gctttgtttt taggattggc
    17941 tgcttgtcaa caacaacatg ctacttctga ggggacgaat caaaggcaaa gcagttcagc
    18001 gaaagttcca tggaaagctt catacaccaa cctaaacaac caggtaagta cagaagaggt
    18061 caaatctctc ttatcagctc acttggatcc aaatagtgtt gatgcatttt ttaatctcgt
    18121 taatgactat aataccattg tcggctcaac tggcttatca ggagatttca cttcctttac
    18181 tcacaccgaa tacgatgttg agaaaatcag tcatctctgg aatcaaaaga agggcgattt
    18241 tgttggaacc aactgccgta tcaatagtta ttgtcttttg aaaaattcag tcaccattcc
    18301 aaagcttgaa aagaatgacc agttgctttt cctagataat gatgcgattg ataaaggaaa
    18361 ggtctttgat tcacaagata aggaagagtt tgatattcta ttttcgagag ttccaactga
    18421 ggcaactaca gatgtcaagg ttcacgctga aaagatggaa acattcttct cacaatttca
    18481 attcaatgaa aaagctcgaa tgctgtctgt agtcttgcac gacaatctgg atggcgagta
    18541 tctgtttgta ggtcacgttg gggtcttagt acctgctgat gacggtttct tatttgtaga
    18601 gaaattgact ttcgaagaac cctaccaagc gattaaattt gctagtaagg aagattgcta
    18661 caagtatttg ggcaccaagt atgcggatta tacaggcgag ggactggcta agccttttat
    18721 catggataat gataagtggg ttaaacttta atagtgttat gatatgacag taatcttagg
    18781 atttttattt ctatttttga tgagttggtg ggttatttca atcgttaata gccagaaacc
    18841 actcaaaaat gaaacattta ttggctatgt ccaaagatac gatattgatg ggaatggcta
    18901 tcaatcatta ccgtgtcctc agaactgaga ggagttcttg aaatcgtaac accactttga
    18961 acaagagtta cttcaaccca ttggctccga cggagtaagt tgctttcgtg aacaccaaaa
    19021 tcagccgcaa tttcttcata agtgcggtat tctcacacat attgaagagt ggccataaga
    19081 aggtcttcta ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct
    19141 gtttttaata cagctaacat ctcttcaaaa gtggtacgct gaacaccaac aagacgctta
    19201 aatcgtgcat cagttagttg tttacttgct tcataattca tagaactact ataccatatt
    19261 ttgtttcgca ggaagtctaa tgctaaaatc ttatcagtga gaagatttct taaagtttat
    19321 tctttgtagt ttcatctgta ttagtacata atttaactta gagaaaatag gaggactaat
    19381 cgaatggaat taaaagattt tacagaaaaa gaacaggaaa tgattaagaa aaggcttaca
    19441 atgtctaata ttagtgacaa agaaactact gagaagattc tggcgctagt accacaagac
    19501 ttgattaagc gaatcccgtt ttttgtcaga aaacatgcta caacacgtac gattaaacgc
    19561 atttcaattg aataccctga actctacgct gtagctcaaa caagtggtga gattccagaa
    19621 aaagaacgcg aagaattgcg tcagattatc acaactatct ttgaacaaaa gatgaataag
    19681 catagtatta agtagagaat gaaaaaatat tttattagcg gtttgggaag caatgcctat
    19741 catagcgagg aagaatctat ctgtctgata ggccattctc ttggaggaga tttagctcgt
    19801 tatctcgcat cggaattcga agaagtaaaa aaactgattc ttttggatgg tggctatcta
    19861 gatttagata agattttacc tttggataca gagttagagg aaactaaaaa ttatatcaaa
    19921 tctcaaattg ttttggactt agatgttctt acttctaaag aaaaatctga agcaaagcat
    19981 tggtcagaaa atatggagaa agctgtaaga cagtcttatc actggaatgt tgagtataat
    20041 agatatgagt tggctataaa ttatgaaaat atagaagcga tactccgcct acggagaaaa
    20101 atacaagctt ttaagagaga agtgggagat accttgttta ttagtcctcg ctatcctaat
    20161 gaagctacat ggagagagga agccctaaaa gaattgccag actattttga tactattttt
    20221 ttagaaaact ttggccatga gctttatact caagcaccta aagaaatcgc tagtctaatg
    20281 aatgagtggc tcgcttattt tctatgagct acttgtattg ctggaaatgg tataagatga
    20341 aaatctacaa gtcactaatt ttcatataac aaaaaaacga acaggctctt tttctgttat
    20401 tcagaagaga acttgttcgt ttttatcttg attttcttaa aaagctctat atacataggg
    20461 attttctggt ttatcgactt tggtaaagct gtcgatttcc aaggttggaa ggttttgttt
    20521 gagttcttta tggtagtgat tgaccagttt tcctttggct gttatccaag tgttgttttc
    20581 atactgccgg gtattgccct tggtcagcaa tccatagaca ccagaatctg cgatacagtg
    20641 gataatgccg aatcggaaca gaaattgact attggcatga ctggggtcgt tatagacaaa
    20701 gcctgtaaac tggattgtct tgccctcaaa ttcatctgga tagtcgtaga tagcctccat
    20761 gacttccata tagttttcat tagtgatctg aatactatct tgggataagt atttatccgc
    20821 cgccgttcgc atttcctttt cataggctga ttttgaaaaa taagaactgg tatctggttt
    20881 caaatattgg cttgtcgtcc cttcgcttgt ctgaatggct agatccgttc cttccgatag
    20941 ggggaaatga taacctttag cagaaacggt ctgagaatcc aagctaacag ttgggaaagt
    21001 taagccgatg acaagtggaa tagccagaag agaaatactc gtcatcttgg ccaatcggct
    21061 gttcagatga ctgtgggttt tgacttgctt catccagata tacaattgaa caattgccaa
    21121 gataaaggaa agcaccatgg aaatataggc cagataggaa tagtgcatgt tgatgtactg
    21181 gtttagtttg cccgacagat ggaggtaaat agtcagttca aaatagccag ctaaaactaa
    21241 aaatcgaatc ataggatgac tccaatcaag agagaatagg ctaaaacgac cagagtcaca
    21301 atcgtaatga agtgactaat aaatcgtgct ttcaagtaat ttttcatcat gagaatattt
    21361 ttgatatcca gcattgggcc aatgacgaga aaggccagaa ctggagccaa accgaaactc
    21421 gagagtagag aagcacctat aaaggcatcc gcctcactac agagcgaaag aagaaaggcc
    21481 aaaagcatca agagcaggat ggcaaaaaga ggagtcgcac tgatagaggt cagaatccga
    21541 gtcggaacgt agacctgtat tatagaagca aagaggcagc caaataccaa ataacgcccc
    21601 gtatcaaaaa attcatcaat ggcctgcaca aagacttgaa aaactttttt tgcagaactc
    21661 aagtaagaaa aatcatgctc atgacaagcc agacgatttt ctttctgaat cggttcttgc
    21721 cagaaaaatc ctagaaaaat tcctagtatt acagccacaa gaatggaacc cagagctcgt
    21781 aatagggcga catggaagga gttgccaaag gcagaatagg tcgcaaaaag aacaatggga
    21841 ttgataacag gtgctgtcac aagaaaagga actgccgtgt aacttggaac ctttttttcc
    21901 agaaaacgat tgatgatggg gacgattcca cattcacaag aagggaaaag tataccgaca
    21961 aaggtcccaa aaaagattct cccccaacga tttcgaggga gaaaatgata aaccttgtca
    22021 ggtgtgatat aaacttcaat cagccctgag acaatgcttc ctatcagaac gaagggaagg
    22081 gcttcaatga taatggagag aaaaatggct ccagtttgaa gtacactaga tgggagttgt
    22141 tgaaaagcag tcatctagtt tttcttttct gctttgactt ttttctcttt gtcatcaggg
    22201 aaagtaactt gtttcaaatc agggagttta gcaaactctt caaacatctt gtccaagtcg
    22261 tctcgttttg taaatttgac agccataggt gtacctcgat tctaaattct acctctatta
    22321 tactattatt ttgcggaaaa gggaaaagtt aaaatttcaa attgagtagc taagagataa
    22381 tatagcttga tattacctga tatatatcat aattgtgcta taattaaata aaaagaaaat
    22441 cattatcaga aaattatggg aggtagtcaa actgacttac tcaattagtg ttgttttgtt
    22501 acatcaagga gataaaaata gtttattaga gtctttgtca atagtggaga gacaaacatt
    22561 aaaagatata gaagttatta ttgtaaatca atctacagag gagatagctt ccattagcca
    22621 acagatgaat ctatcattta atattaagat tataaatgag aattcttttg ctgagttgtc
    22681 tgatatgatt acaggagatt atattacgtt tctatcttca aatgattcat tatttgattg
    22741 gacatttgaa aagatgtatc atgcgataaa attatccgat tctgatgttg ttcttggtca
    22801 ttttgctgat ttggttgatg gagtatttta cttttatcct tggggggata attggttgac
    22861 agaaaattta acgaatgttc aagttttaca aaagatggat gatacagatc atcgaattag
    22921 aaaacaatat cgctcattat ttggaaaatt attcaatagt aagcttttac gaaaaataaa
    22981 tcaatttgat ataaacaacc ttatttggag actttatatt cactctaaaa ctgcaaccta
    23041 tattaatttc ccgacatata tctataaacc tgttatagat gctaaacctc taaaagactc
    23101 ctacaaaatc atattagaaa attatgaaaa tagaatcaaa gattgcgccg tcttagaaaa
    23161 ctatgatata gaaagagcga aaaaacaata tattcaagaa ttggcaaatt ttagtgcttg
    23221 gttaaaaaat gacggtgaat atttagattc tgatattgtt tatcataagt taatagctgc
    23281 agagaaagga attttccctt ttcttgagct tgatagatta gattttacga ttataagtaa
    23341 taattgtgtt ggaggattaa tttataaaca gcttggtttt caatatagaa caccttttgt
    23401 tggtttattt attcttcctg atgattatta taaacttaca aagcattttc gttattatat
    23461 ggaacaagaa cttgttttcg aagaggaact tatttcaccg agctggactc atgaagttta
    23521 tcctttgggg cacttaggag atatagatat tcattttcta cattattcta gtattgaaga
    23581 agcacgaact aagtgggaaa aaagaaaaaa acgcataaat tggaataatc tttattttaa
    23641 atttgataat aaagattcag ctagtgaaga aattttaaat aagatggata atcttcctta
    23701 ttctaataaa ttaattttag tcaatcgtcc atataaaaat ttgaaaagtc aatgtgttat
    23761 tccaggtcag gaacatcttc cagaactggc tattatgtct gatccattaa atacttttga
    23821 tatcatggct tggttaaaaa aaggtggcaa tgctctttaa gtgcaagtta ttgcgctgta
    23881 gcatataaat ctatttccta catatttttt aaatgttcta cgagttaatt tgaaacgttt
    23941 agcttgtggt ataatagatt tatggataaa aaatatgaaa aaatctctca ggatttggga
    24001 gtgatgttaa agcaaattga taccgttcta agtttgacag ctgaaggggc gactattccc
    24061 tttatcgcgc gttatcgcaa ggacatgact ggtagtctgg atgaggtggc gattaaggct
    24121 attattgatt tggataaaag tctgacaaat ctcaatgacc gtaaggaagc tgtcttagct
    24181 aagattcaag aacaaggtaa gttgaccaag gaattggaag aagctatctt agttgccgaa
    24241 aaattagcag acgttgaaga actctatctt ccttataagg aaaagcgtcg taccaaggca
    24301 accattgccc gtgaagctgg actctttcct cttgctcgtt tgattttgca gaatatagtt
    24361 gacttagaga aagaagctga aaagttcgtc tgtgaaggat ttgcgactgg caaggaagcc
    24421 ttgaccggtg cagttgatat tttggtcgaa gccttatcgg aagatgtgac cttgcgttct
    24481 atgacttatc aggaagtgct gagacactct aaacttactt ctcaagccaa ggatgaaagt
    24541 cttgatgaaa agcaggtttt tcagatttat tatgattttt cagagacagt tggaactatg
    24601 caaggctatc gtaccttggc tctcaatcgt ggggagaaac ttggtgtctt gaagatcggt
    24661 tttgaacatg cgacggaccg tattcttgcc ttctttgcta ctcgtttcaa ggtgaaaaat
    24721 gcttatattg atgaagttgt tcagcaatcc gttaagaaaa aggtcttgcc tgctattgag
    24781 cgtcgtattc ggacagaatt aactgagaaa gctgaagagg gagctatcca acttttttct
    24841 gacaatctgc gcaatctcct cttggttgct ccactgaaag ggcgcgtggt tcttgggttt
    24901 gacccagcct ttcgtacagg tgccaagcta gctgtcgtgg atgcaacagg aaaaatgctg
    24961 acaactcagg ttatttatcc tgttaaacca gcatcagctc gtcaaatcga agaagccaag
    25021 aaagatttag cagatttaat tggtcaatac ggtgtagaga ttattgccat tggaaatgga
    25081 acggccagtc gtgaaagtga agcttttgta gcggaagttc tgaaagattt ccctgaagtc
    25141 agctatgtta tcgttaatga aagtggtgct tctgtctatt ctgccagcga acttgctcgt
    25201 caggagtttc cagacttgac cgttgaaaaa cgctctgcca tttctatcgc ccgtcgtttg
    25261 caagatcctc ttgcggaatt ggtcaaaatc gatcctaagt caattggtgt cggtcaatac
    25321 caacacgatg tcagtcagaa gaaactatct gagagtctgg actttgttgt cgatacagtg
    25381 gttaaccaag ttggtgtcaa tgtcaataca gctagcccag ctcttctttc acacgtagct
    25441 ggactcaata aaaccatttc tgaaaatatc gtcaaatacc gtgaggaaga gggaaaaatc
    25501 acttcacgct cccaaatcaa gaaagttcct cgtttggggg ccaaggcttt tgaacaggct
    25561 gctggtttcc tccgtatccc tgaaagtagc aatatccttg ataatacagg agttcaccca
    25621 gaaaattacg ctgccgttaa ggaactcttc aaatgcttgg atattaagga tctgaatgaa
    25681 gaggcccaaa gcaaactcaa gtcgctttca gtcaaggaaa tggcgcaaga gttagacctt
    25741 ggtccagaaa ctcttaaaga tatcattgca gatcttctca aaccaggtcg agatttccgt
    25801 gattcctttg atgctccagt tctccgtcaa gatgtcctag atatcaagga cttagtggtt
    25861 ggacaaaagc tagaaggagt ggtgcgtaac gttgttgatt tcggtgcttt tgttgatatc
    25921 ggaattcatg aggacggtct catccatatt tcccatataa gtcgcaagtt tatcaaacac
    25981 cctagtcaag tggtggcagt tggagatttg gtgagcgttt gggttaagaa aattgatact
    26041 gaacgtgaaa aagttaatct gtctctccta gctccaaatg aaactgactg attacgtcaa
    26101 gcaggtttca ctagaagact tcggcagacc ttttatccat catgtccagt ggaataggcg
    26161 tctacgttcg acaggtgggc gatttttccc aaaagatggg catttggatt ttaatcccaa
    26221 ggtttatcag gaactggggt tggacgtttt taggaaaatt gtccgacatg aactctgtca
    26281 ttatcacctc tattttcaag ggaaaggcta tcaacataag gatcgggatt ttaaggaact
    26341 gttgaaagca gtggatggat tacggtttgt accatccttg cccaatagta actccaagcc
    26401 aatcaagctc tatcgttgcc aatcctgcca gcaaacttat cagcgtaagc gtaggattga
    26461 taccagacgc tatcgctgtg gactttgtcg aggtaaattg ctactaataa atcagcctga
    26521 ggactgatga aagccgagcc tacccgtgat atactatgtc taacctagca gaaagaggaa
    26581 atatcatgaa cagtaagttt tataaaatga gacgaaatcg catgatttca ggagttttag
    26641 caggtctgtc agacaagtgg aactttgatg ttacccttgt acgttttctg tttgccattt
    26701 ttacagtcgc aaactttgga cttggggtga ttatctatat catcctagct tctatcatgc
    26761 caaccaagga agaaatcgaa gcagaaatgt acggaacagg cccacgtaaa cgcaaagaag
    26821 ctcaagccat tgacgataat gaaggctggt tttggtgagg ttttacaaaa gatttggaat
    26881 acgcaaaaag ctttaaatca atagtctaaa ctgcttgatt taaagctttt ttacttttat
    26941 actcaataaa aatcaaagtg caaactagga agccagccgc aggctgtaat ttagtcggca
    27001 atgtgaagtt gacatagttt gcactttgat ttttgaatag tattaataat atttcgtcag
    27061 cttcatccac aaactatagt ggattggaac tagaatagta cacctctact tctaaaatat
    27121 tgttagaaat cgatttgact gtcctgatcg atttgtccta ttcttatttc attttactat
    27181 aaaagcagta atttaaatgc agttttttaa tctatttttg ctgctgagac aatacatttt
    27241 tggaaaaatg gtggatgctg ataacaactg ataaccagca aataacataa gcagtgccgg
    27301 taaattctgt accgataaag tgtgtgtgtt caactaagag ctgaccgatg aatggagaga
    27361 gcagatagag aaatccgatg agtatatgtt ctttgtgttt cattaaaacg caccttcttt
    27421 ccttataggt tgaacgactt gcaagtgtta aattgaatgg tatgttatct aggtaacctt
    27481 actaaaatgt tagttcccgc ttcctccttt ttaaagtaag ccttttcata cttatatttt
    27541 acaactttaa aaataggaaa tcaaatcatt ttctaagtaa ttttgcttat atttcaccca
    27601 atcttacaaa aatgtaagat taaagtctct tttgtaaggt taggttatgg caagcggtct
    27661 ttttttgatg taaactagac tcataaagaa caaaggagta acatcatgaa acaaatctta
    27721 cataaaaaaa ctagaaaacc aagtcacaaa gaaattgagc gcattcagct gggatgcact
    27781 atgatgcaag ctacatttca tttgatggga tattaagaaa ggagattctc atgacacttt
    27841 tagatgtaaa acacgttcaa aaaatttata aaactcgttt tcagggcaac caagtagagg
    27901 ccctcaagga tattcacttc accgtagaaa agggtgacta cgttgctatc atgggtgagt
    27961 ctggttctgg taaatccact ctgctcaata tcctagctat gctggataaa ccaagtcgtg
    28021 ggcaggttta cctaaacgga actgatacag caactattaa aaattcacag gcttctagtt
    28081 tccggcgtga aaagctagga tttgtcttcc aagactttaa cttgctagat actctgtctg
    28141 ttaaggacaa tatcttgctt ccgcttgtct tgtcaagaag acctataacg gagatgatga
    28201 agaaattggt gatgacagct gaaaatctgg gtatcaacca attgcaagag aagtaccctt
    28261 acgagatttc tggtggtcag aaacagcgtg tagcagtagc ccgcgccatc atcacagaac
    28321 ctgaaattct cctggcggac gagccaacag gagcccttga ttccaagtca tctgcagcct
    28381 tacttgatgt ctttaatgaa atcaatgagc gtgggcaaac catcctcatg gtaccccact
    28441 caacagcagc tgctagcagg gccaagcgtg ttctctttat caaagacggc attctttaca
    28501 accaaatcta ccgtggagag aagacagagc gtcagatgtt ccaagaaatc tctgatacct
    28561 tgactgtcat ggcaagcgag gtgaatta
//
LOCUS       DAVHSL010000029        27231 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000029 DAVHSL010000000
VERSION     DAVHSL010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.029"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(57..461)
                     /locus_tag="VVR39_001246"
     CDS             complement(57..461)
                     /locus_tag="VVR39_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6030737.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(458..622)
                     /locus_tag="VVR39_001247"
     CDS             complement(458..622)
                     /locus_tag="VVR39_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030738.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(919..1038)
                     /locus_tag="VVR39_001248"
     CDS             complement(919..1038)
                     /locus_tag="VVR39_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU6030739.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(1041..1271)
                     /gene="blpU"
                     /locus_tag="VVR39_001249"
     CDS             complement(1041..1271)
                     /gene="blpU"
                     /locus_tag="VVR39_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6030740.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(1340..1609)
                     /gene="blpJ"
                     /locus_tag="VVR39_001250"
     CDS             complement(1340..1609)
                     /gene="blpJ"
                     /locus_tag="VVR39_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU6030741.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(2076..2273)
                     /gene="blpI"
                     /locus_tag="VVR39_001251"
     CDS             complement(2076..2273)
                     /gene="blpI"
                     /locus_tag="VVR39_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU6030742.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2555..3142
                     /locus_tag="VVR39_001252"
     CDS             2555..3142
                     /locus_tag="VVR39_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU6030743.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            3069..4712
                     /locus_tag="VVR39_001253"
     CDS             3069..4712
                     /locus_tag="VVR39_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6030744.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            4723..6084
                     /locus_tag="VVR39_001254"
     CDS             4723..6084
                     /locus_tag="VVR39_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU6030745.1"
                     /translation="MNSNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFSYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREILITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            6141..6296
                     /gene="blpC"
                     /locus_tag="VVR39_001255"
     CDS             6141..6296
                     /gene="blpC"
                     /locus_tag="VVR39_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU6030746.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(6338..7678)
                     /locus_tag="VVR39_001256"
     CDS             complement(6338..7678)
                     /locus_tag="VVR39_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6030747.1"
                     /translation="MNIAWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(7692..8429)
                     /locus_tag="VVR39_001257"
     CDS             complement(7692..8429)
                     /locus_tag="VVR39_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6030748.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSTEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8434..8772)
                     /locus_tag="VVR39_001258"
     CDS             complement(8434..8772)
                     /locus_tag="VVR39_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6030749.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKQGE"
     gene            9048..9377
                     /locus_tag="VVR39_001259"
     CDS             9048..9377
                     /locus_tag="VVR39_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6030750.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9545..10594)
                     /locus_tag="VVR39_001260"
     CDS             complement(9545..10594)
                     /locus_tag="VVR39_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030751.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10591..11322)
                     /locus_tag="VVR39_001261"
     CDS             complement(10591..11322)
                     /locus_tag="VVR39_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030752.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVESLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11390..11800
                     /locus_tag="VVR39_001262"
     CDS             11390..11800
                     /locus_tag="VVR39_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6030753.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11810..12097
                     /locus_tag="VVR39_001263"
     CDS             11810..12097
                     /locus_tag="VVR39_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030754.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12259..12498
                     /locus_tag="VVR39_001264"
     CDS             12259..12498
                     /locus_tag="VVR39_001264"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030755.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYYSPFHN"
     gene            complement(12832..13968)
                     /gene="dnaJ"
                     /locus_tag="VVR39_001265"
     CDS             complement(12832..13968)
                     /gene="dnaJ"
                     /locus_tag="VVR39_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU6030756.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(14312..14716)
                     /locus_tag="VVR39_001266"
     CDS             complement(14312..14716)
                     /locus_tag="VVR39_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU6030757.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(14727..16550)
                     /gene="dnaK"
                     /locus_tag="VVR39_001267"
     CDS             complement(14727..16550)
                     /gene="dnaK"
                     /locus_tag="VVR39_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU6030758.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(17019..17543)
                     /gene="grpE"
                     /locus_tag="VVR39_001268"
     CDS             complement(17019..17543)
                     /gene="grpE"
                     /locus_tag="VVR39_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU6030759.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17570..18604)
                     /gene="hrcA"
                     /locus_tag="VVR39_001269"
     CDS             complement(17570..18604)
                     /gene="hrcA"
                     /locus_tag="VVR39_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU6030760.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQESANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18768..19277)
                     /locus_tag="VVR39_001270"
     CDS             complement(18768..19277)
                     /locus_tag="VVR39_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU6030761.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSCFGLFYFEQ
                     GQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIYGYFR
                     LKRKYRVDE"
     gene            19884..22217
                     /locus_tag="VVR39_001271"
     CDS             19884..22217
                     /locus_tag="VVR39_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6030762.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            22230..23693
                     /locus_tag="VVR39_001272"
     CDS             22230..23693
                     /locus_tag="VVR39_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6030763.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            23693..25261
                     /locus_tag="VVR39_001273"
     CDS             23693..25261
                     /locus_tag="VVR39_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6030764.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            25318..26115
                     /gene="psrA"
                     /locus_tag="VVR39_001274"
     CDS             25318..26115
                     /gene="psrA"
                     /locus_tag="VVR39_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU6030765.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            26126..26734
                     /locus_tag="VVR39_001275"
     CDS             26126..26734
                     /locus_tag="VVR39_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6030766.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(26682..27227)
                     /locus_tag="VVR39_001276"
     CDS             complement(26682..27227)
                     /locus_tag="VVR39_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6030767.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         8846 a         5353 c         4857 g         8175 t
ORIGIN      
        1 taaaagggta agtattgcaa aaacacttac ccttttcttt tatacttcat taagctctac
       61 tttttataat acttcaagcc ccacatgagc agaagcatga tgattaagca gagaacagcg
      121 ccaatataag cgattagttg ttgataagat tctcctgctg tgatacctct atacaaacaa
      181 ataatagaca taaaacctgt caagccgata aacataagtt gattggttct aggactaacc
      241 aaatcatcat cttcaaactc tcttatcctc atttccctag tgagataaac agtaaccaaa
      301 atagaagcca agttaataac tactaaaaga aattggaaaa ctacggaaaa atttaaaaac
      361 tgacgagata gaaatagata agtagaaaca agcaagggca actgacctaa gaacaatctc
      421 gcaaggaaga tgttccgttt tttagcaaga aaagttttca tttcttttct cctttctttt
      481 tattgatagc aaaatagatc ataactgcaa tcacataggc tatggtataa aatagctgat
      541 accaagcact ctccctaagc ggatatagaa agatggacat gattagatac agaacgaaaa
      601 taatcagtat ttttttcttc ataagatttc ctcctaaatg tgcgatttat cttagttgag
      661 caagaacatt tacactgcta gtatagcact tattttgacc ttggatcact caaatcataa
      721 atggtcatca aaacctcttg aattgtaaaa attaaaaaag caagcatgaa aaacatactt
      781 tcctctttat attgtattga taccaacttg tttgcagact tttcatcctg ctatcacata
      841 tcattttgac aggcgaaaca aaattaaaga aactcccctg taaattaagc tagcaaatac
      901 aggggagaaa tttatttttt agggggtact atctgtatcc tttttgggaa attttgaaaa
      961 tatttttcta attaaattat ccatataagg accaaatata ccaactacta aaccaataat
     1021 aaaactttta aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt
     1081 atagctccac ccgcagcacc agttgctgca ccttgccatg ttcctgtttt aatgcctagt
     1141 tgaagacctc ttgctgctcc tcctccaaca cctgctttgg caaaatctcc ccaattgcat
     1201 ccgccacctt caacgcaagc aagcatttca gtatccataa cagaaaattg tgacatcatt
     1261 tttgtatcca tgacaaatac tcctttttta aaaaactaaa ataaatcaga atagaatcct
     1321 cataatttta ctataagtct taccaactta gtcccaattt atcaccaacc atacctccta
     1381 agcatgttaa tccaccccca attgcaccaa tgtgtgctcc aacaaatgca ccagcaagtc
     1441 cagctactcc taaagtggcc aaacctgctc cagttccacc agttataatt cccgtagtga
     1501 ctcctgtaat cagtgcattt tgacaatcag tggagctata ccccccttca actttcgcaa
     1561 gcatttcagt atccataacc tctaactgtg acaacatttt tgtattcatg atgaatacct
     1621 cctttttatt ttcaatttgt taccaaagtc ttaaattcaa taaacaaata gattttttat
     1681 agtatctttt tgattttctt aaaaaagtat acacgtctac tatcttctta aaggtagcag
     1741 tacctatttt ttagtctaag atttcaataa tcttgagtat ctaaaatatc ttaatttcgt
     1801 tattctcctt gcaataaaaa gttttactat actatttatt aacttgcaga aagcaaaaaa
     1861 tattagtaaa taatagttta tagttaagtt ttttattcct accaatccat caactaagta
     1921 aagcatcaac gattacataa acgattgata atataattaa aattttgcta actatcttat
     1981 tctcatcatt cttagataac tttgatattt tgtaagtaag taaataagac agtaaattaa
     2041 tagcgataat aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa
     2101 cctacacaaa taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt
     2161 actgctccaa tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt
     2221 tcgagttctt cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat
     2281 actccttttt tcttttttta tttttgtctt gttgtaactt tgataagttt agtatatcat
     2341 cgttttttaa aatttttcat ccagatcttg aattgtcatc gaaacgtctt gaattagctt
     2401 ttttatttca agccacctct aaatgtttaa aaaaaataat ttctaatcac ttttttacca
     2461 ttcaggaagt tttaatgact attcaagatt tcataaaata tgaacttagt tttatgacat
     2521 aatagaccta tccactatat gaaaggaatt gccaatgact tcttataaac gtacatttgt
     2581 tcctcaaata gatgcgagag actgtggtgt cgctgcctta gcctcgattg ctaaattcta
     2641 tggttcagat ttttctctag ctcacttgag agaacttgca aagaccaata aagaagggac
     2701 gactgctctt ggcattgtaa aagccgctga tgaaatgggc tttgaaacaa gacctgttca
     2761 agcagataaa acgctctttg acatgagtga tgtcccctat ccatttatcg ttcacgttaa
     2821 caaagaagga aaactccaac attactatgt tgtctatcaa acaaagaaag actatctgat
     2881 tattggtgat cctgaccctt ctgtaaaaat cactaaaatg tcaaaagaac gctttttcta
     2941 tgaatggact ggagtagcta tttttctagc taccaaaccc agctatcaac cccataaaga
     3001 taaaaagaat ggtctactaa gcaagcttcc ttcctctgat tttcaaacaa aaatctctca
     3061 ttgcttacat tgttctctca agcttattgg tcactattat caatataggt ggttcttact
     3121 atctccaagg aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca
     3181 tctcagttgg tctggttatc acctatatcc tccaacaagt catgagcttt tccagagatt
     3241 atctcctaac cgttctgagc cagagattaa gcattgatgt gattttatcc tatattcgcc
     3301 atatttttga acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac
     3361 ggttcacaga tgctaactct attatagatg ccttggcttc taccattctt tctctttttc
     3421 tggatgtttc tattctgatt cttgtagggg gcgtcttact ggcacaaaac cctaatctct
     3481 tcctcctttc tcttctttcc attcctatat acatgttcat catcttttct tttatgaaac
     3541 cttttgaaaa aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta
     3601 tcgaagatat caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc
     3661 aaaatataga cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt
     3721 ctattttaca aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat
     3781 ggtttggcgc tcaattagtc atgtcgagta aaatttctat cggtcagctg attaccttta
     3841 acacactttt ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac
     3901 tccaatctgc gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat
     3961 ttcaagttca agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg
     4021 acctttctta taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta
     4081 aacaaggaga taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca
     4141 aaatgattgt caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata
     4201 ttaaaaacat tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct
     4261 atatctttaa tggctctatc ttggaaaatt taaccttggg cggtaatcat atgattagcc
     4321 aagaagatat tctaagagct tgtgaattag ctgaaatccg tcaagacatt gaaagaatgc
     4381 ctatgggcta tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac
     4441 gaatagccct cgctcgtgct cttttaacta aatctcctgt tttaatacta gatgaagcta
     4501 ctagcggtct tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg
     4561 ataaaaccat tctctttgta gcccatcgtc tcagtatagc cgaacgaacc aaccgtgtca
     4621 ttgttcttga ccaggggaaa atcattgaag ttggtagcca ccaagagtta atgcaggcgc
     4681 aaggcttcta ccatcatcta ttcaataaat aaggagaatg tcatgaattc taatcttttt
     4741 agaagcgtcg agttttatca gagacgttac cataactatg cgacagtgtt aattatacct
     4801 ctttcattac tgtttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact
     4861 gttacttccc aaggagaaat cgcccctaca agtgtcattg catccattca gtcaaccagt
     4921 gataatccta tcctagctaa tcatttagtg gcaaatcaag tagttgagaa aggtgactta
     4981 ctcatcaaat actctgaaac aatggaagag agtcagaaaa ctgccttagc aactcaatta
     5041 caaagacttg agaagcaaaa agaaggactt ggaattttga aacaaagctt agaaaaagcg
     5101 actgatcttt tttctggcga ggatgagttt agctaccata atacctttat gaattttact
     5161 aaacaatccc atgatattga actcggtatc tcaaagacta acactgaagt ttcaaatcaa
     5221 gccaatcttg ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa
     5281 caaattggag aatatcaaga gctgagagat gctatcataa ataacagagc tcgcttacca
     5341 actggcaatc cgcaccagtc aattttaaat cgttatcttg tagcctcaca aggacaaaca
     5401 caaggaacgg cagaggagcc atttttatct caaattaatc aaagtattgc aggtcttgaa
     5461 tcatctatcg caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat
     5521 aatagtttag caaccaaaat tgaagtactc cgcactcaat ttttacaaac agcttctcag
     5581 caacaactaa ccgtggagaa ccaattaaca gaattaaaag tacaactaga tcaagcgaca
     5641 cagcgcttag aaaacaatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc
     5701 gaatttgaag gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctatc
     5761 atcacagata caagagaaat actaatcact tactacgtag cttctgacta tctacctcta
     5821 ctagataaag gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcattacc
     5881 atcatcggcc aacttcagac aattgatcaa actcctacca gaacagagca aggcaatctc
     5941 tttaaattaa ccgctcttgc aaaactatct aatgaggata gtaaactcat ccaatatggc
     6001 ttacaaggtc gcgtcactag tgtaactgca aagaaaacat attttgatta tttcaaagat
     6061 aaaattttaa cccattctga ttaattttca gataacactc tataactatt tattatctta
     6121 tcaaaaagga gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa
     6181 caactaccga actcaaccaa attacaggtg gaggatggtg ggaagaactc ttacatgaaa
     6241 caattttaag taaatttaaa atcacaaaag cacttgagct acctattcag ctataaaaac
     6301 aagaccgaga aacaagaact ctcggtcttg ttttttatca ttctgcatgt atcacagtaa
     6361 gtacctgacg aaagacttga ttttggcagg tagtatttag attggtattg ggatgacttt
     6421 ccacaatttt cataacggta tagagaccaa ctcctctctc ctccccttta gaacttgctc
     6481 caaaggagaa gatttcagaa atatcgatgc cctcttcttt gatggagttt tcaatgataa
     6541 aagtctcctg tgctccattt tttaaaaagg cgattgaaac atgaggttga ctggcctctg
     6601 cactagcttc aatagcattg tcacaaagga tagacacaat ggttagaaaa tcaagtaggc
     6661 tcatcccctc aacctgaatc tcctcaggaa cttcaacatt aaagacaatg ttcttttctc
     6721 tagcttttat aaattttcca gctaggagac tcttgagggc acggtcacga atattcacca
     6781 atctgcccag gtcatattta ttgtcctgca atttctgact ggaatccctt aagaccgagt
     6841 cgtagatctc ttttatctgc tccatatcct cctcttcaat gcccaaacgt aagctggtta
     6901 agaggttagt gtagtcatgg cgaaaactcc gaatttcctt gtaaagttcc tctatatgcc
     6961 gactatagcg ttccatatct ctgtagcgca aggtctgctc ttggttcagt tcctcctgaa
     7021 gtttttcctt caaataggta tccaatttct tgataccccc cataaaaaag agtaggtaaa
     7081 acactaggat gagatggcga acagtcgttg attgaatacc ttgttcatat tcaaggtaag
     7141 atagactttg catcactaga taataagccc ccattgccca gttaatctta gtaagagact
     7201 tttgaaaacc tgtatctaga aactcccttc tcaatctagt gaaatcatag tctaaccatt
     7261 tcaaaaagac taaaactatg aagcaaacga atatcataat caataaaaag ataggattgc
     7321 catccccatc tacaattcct tgccccaaaa atggaagcac aaaataggaa acacctctgt
     7381 aaaagagctc tactaatatc attgggaaga gaccataaaa aataaggatt tttttaggaa
     7441 gccctcttaa caataagaaa gatagaccta taccgaacaa aggttctata aaataggaca
     7501 aatatttact tacagccaaa aattgaaaag tcgtaaaaat gatccctaga agaaatttca
     7561 gaagaaaggc cttaaaaatt ctatcgaaag tgagaccaat tccatctact ttaaagaaaa
     7621 tgacaatttc tagtccatta ataacaagtg catacaacaa tatccaagca atgttcataa
     7681 actctcctag ctcagtgtaa gttattaata gcctcagaca cttccctgac cttataacgc
     7741 gcgatcagac aacttccacc attgggaaag aaaaggagtt tttctttctt atccaaatgc
     7801 accacatttg caggattgat gagaaaagag cgatggcact gcaagagacg gggttcctgc
     7861 ttgaaaacct cctctaaact cgctgtaaat tccagcctgt ctgtcttggt atagagaata
     7921 acacgatggg gtcttgggga tgtttcgaga tagtaaacct ctttaaaagg atactgaaat
     7981 tgggcaaatt ttgatttaaa gtaaaagcaa tcttccgcca gacttttact atcttgacta
     8041 ttggcataga ggagggctgt ctcgattcga gattcaaact cctctgtcga aagggcctta
     8101 tcaatatagt ccagagcaga cacttggtag cgaaaggaca ggggcataaa ctccgagtga
     8161 gtcgtcacaa agacaatcag ggcatagggg tcttgttccc gaatctttct agccacttcc
     8221 agccccttca tctcctcatt tcgaatctca atatccaaaa agaatagctg atgggccccc
     8281 ttctcatgca cctctgccag cagttggtct ggcttgccaa atacctcaaa agagctggga
     8341 gtgatatgat gttccttcaa gagtttctca atcgtcgttt caatcctagt ctgttgggaa
     8401 aaatcatcct ctaaaacaaa tattctcatc tttttactct ccttgtttta accatttttg
     8461 acgaatttct ctatagcgac gtctggcata cttgacagcg tattgacctt cttctccgag
     8521 aaaaaggatt ctttcttgaa aatcaatcga ttttaattta tcaagattaa ccaaacaatt
     8581 tcgatgacat ctcatcaagg tttccccaca ttggttctca agattactta aattttgaag
     8641 catattaaaa ctagcttctt ctgtaacaat ctgtacggta tgggctttag ttggatgtgt
     8701 ttggatatag taaatatcgt cgatgtttac tttatagact gttttctgcg tctgaataat
     8761 catatatttc attggattct cctcctaaga aaagaataac agaaaaggtc tagcccaagc
     8821 acacccaatc ctaaacagtc tttgaaaact cctaaaagga ttattttcta caacatcatg
     8881 atgagcttac aactatttta tcataaaatt cactcagcgc aattcaagac atttcaatga
     8941 caattaaaga tttgaataaa aaaaaagaat taaaagtgat aaactaacag tatcaaaaca
     9001 cagttgccag aagtaagact ggcacccaga ttaaaggagg cattcccatg acagatacag
     9061 accccatcaa aagagctcat actttgatta ctgacttaaa caaagcctac caagcatgca
     9121 aacaggcaag cgctgacgac gtccgctttc aggagcaatt aaactctatt cttggttttc
     9181 tagccaaggc tgaaacagtg gataatcgat tcttgattga actagaaaaa ttttaccaga
     9241 cttccagtct tctcatggga ctcagcgctc ttgatccaga tgctccaact cgcgccgctt
     9301 ggcgggccta tgaccgcttc cactttgacc aagtcaagac caagttaata ctcaatgaaa
     9361 atcaaagagc aaactaggaa gctagccgca agctgtactt gagtacggta agacgacgct
     9421 gacgtggttt gaagatattt tcgaagagta taagtctcta cggaccaacc attatcctgt
     9481 agtaacaaaa aagaagctga gacaaactga actcaacttc ttttttagtg tcgtatcagc
     9541 aatgttagtc ctgcatctga cgttttacct gataaggcaa atacaagact agtaaaacca
     9601 aaccagctcc tagtaaggct agaagggcta gtttttcttg gaaggtaatc aacccaacaa
     9661 ctaattccac aagtaaaaca aaactggtca atcctcgaac tacctcctgt aagccttttt
     9721 ccttttgccc cttgtccagc ggaaagagtt gggtcaaata ctggtagtca aaggcatgat
     9781 agagggccag caactggaag agcaagaggt agttaaagag aactaccact gctgtcgcaa
     9841 tccaagcttg ctcgataaaa acctgcgcca gtacggaaag taagagaaga cgaagactga
     9901 gagcaaagag gtcgccattt cgcagataag aacgcagata gagattttgc caaatcttcc
     9961 caggcacctt ctgaacagcc tttaagataa agtccagata ggcacgacgc ttgacactgt
    10021 ttgaaattcc cttgacctgc gtaaagaggg caaagaaacg aagcaagact tgcttacgct
    10081 tgctttcttg agaaataaga tagtcccagt ccagtccagt ttcagtaaaa aatttgctgg
    10141 ccttttgacg aaagtggaaa tattttccta cccccaataa aagcacatat agcagaaaaa
    10201 ctggcaagcc ataacccatt gctaaaaata aaggcgcaaa taacagcaag aaaagggtct
    10261 gtacaaagag ccaaaagact agggaaatgc cagtttgacg cttgagatgg agcttgattt
    10321 cctcttctcc aactaagaga aagagcttgt ctggagcctc catataggtg gcaattcctc
    10381 cccaaagtaa gagtaaaaca gacgtaattc ctacaaacaa aaggataggc caatgatttt
    10441 caggaaaatg ttgtaagagt tgactgtact ggtaggctag aaagcccaac aggacaagca
    10501 ggaataagac aaagtggtca ttgagcacat agcgcagata accaagacac tccttacgaa
    10561 aggcctgctt tctctttaaa aacaagtctt tcatagatcc tcctctttgg tcagagccaa
    10621 gtaaatatca ttcaaactag cctcaggcat atcaaaggct tcacgtagtt gcaggagatt
    10681 gcctttggca cgcacctctc ccttgtgaag aatgacaaag gcatcacaca tcttctccgc
    10741 cgaatccagc acgtgggtac tcatgagaat agacttgccc ttttgcttct ccacttccaa
    10801 aagctgaatc aaatcagaaa tagccagcgg atcaagacca aggaaaggct catccacgat
    10861 gaaaagactt ggatccacca caaaagcaca gataatcatg accttctgct tcatcccttt
    10921 tgaaaaatga acagggaacc agtctaattt ctggtccaga cggaacatct ttaacaagga
    10981 ctctactcgt tcgaaagcca ctttttgctc aataccgtaa gccatagcaa ccgtttcgat
    11041 atgctctctg agggtcaatt cctcatacag actaggcgtc tcaggaatgt agccaatctg
    11101 cttgcggtag ctagtcgcat ctccttgcag agtcaggcca ttgatattga tggagccact
    11161 ataaggtgcc aacagaccga taatctcatt gatcgtcgtt gatttcccag caccattgag
    11221 accaatcaaa ccgaccaact gcccactttc aacagtaaag gacacatctt tcaaaacagg
    11281 aacatgaaca tagccacctg tcaggttttt aatttctaac atattttctc caaatctggt
    11341 ataatgtagc tatattatat caaaattcag tacagtagag gtagatttta tgtcagattg
    11401 cattttttgt aaaatcatcg caggggaaat tcctgcttca aaagtatatg aagatgagca
    11461 ggtccttgcc tttcttgata tctctcaagt aacactagga cacaccttgg tcgtgccaaa
    11521 agaacactat cgcaatcttt tggagatgga tgctacgagc gccagccaac tctttgccca
    11581 agtaccaaaa gtagctcaaa aagtcatgaa agtcactaag gctgctggta tgaatatcat
    11641 ttccaactgt gaagaagtcg ctggtcaaac agtttttcat actcacgttc accttgtgcc
    11701 tcgctacagt gctgacgatg acctcaagat tgattttatc gcccacgaac cagactttga
    11761 caaacttgct caagtcgctg aaaccatcaa aaacgcttaa ggagttgcta tgaaattatc
    11821 caacctactg ctatttgcag gagctgcagc cggaagttat ctggttacaa aaaatcgcca
    11881 aaccatcaca gatgaagtct tgaataccac tgaccgcgtt caagctatca aggacgatgt
    11941 ggatattatc caaaacagcc tgcaaatcat taaccagcaa aaagaactta tcaaggaata
    12001 ccaagaagac ttgacttaca agtttaaggt cttggaaaag gatatccaga ctagactagc
    12061 tgtgataaaa gaaatgcagg gaactgaaga taagtaaaaa gagccccccg gctctttttt
    12121 aaaacgtaaa caagttatag tgaattgaat ttagaatagc acaccatagt ttctaaagca
    12181 ttgttagaga ttactttaaa atcctcttat caatttgttc atattctatt tcaatctatt
    12241 atatatatcc catcaactat gcatcataat ttaggtaact catactcaat aaaaatcaaa
    12301 aagcaaacta gaaagctagg cacagactgc tcaaaacacc gttttaaggt tgtggataga
    12361 actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt
    12421 aaccataccc atggcaagcc gacgctgacg tggtttgaag agattttcga agagtattat
    12481 tcaccatttc acaactaaat cgaagacttt ctgccgtaat gaaaacacct gaaacagctt
    12541 ggtttcagct gtccggaaac tttaaaactt aggttcaaag tttaggtatg gaacttcgaa
    12601 ggaggtcact accgtccgtc attacttagg aaagtcttaa aaaatctata aagtaaaaag
    12661 agcccgacag ctctttttgt ttatactcaa tgaaaatcaa aaagcaaact aggaaactag
    12721 ccacgggctg ctcaaaacac tgttttgagg ttgtagatac gactgacgaa gtcagtcaca
    12781 tatatacgac aagccgacgc tgacgtggtt tgaagagatt ttcaaagagt attattctcc
    12841 atcaaaggca tctttaatat ggtcaaagaa gccttttttc tttggattta ctttcaagtc
    12901 accagcagcc gcgaattctt tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt
    12961 tacgacatta acagtaacgt attggtcacc aactgcaccg ccacgaaggc tcggtgcccc
    13021 cttactacgt aggcggaatt tcttaccagt ctgagttccc tctggaataa ccaattcaac
    13081 atcaccgtga acagttggaa tatctactgt atcaccaaga gccgcttgga caaagttgag
    13141 gttgagattg tagaagatag tcgttccttc acgttcaaac ttgtcgctag cttctacaga
    13201 aactactaca tacaagtccc cataaggtcc accgttaaag cctgcttcgc cttgaccagc
    13261 gaggcgaatt tgttgacctg tttccacacc agcagggatt ttcacatgta cgctatgagc
    13321 ttgtttctca tgacctgttc catgacaggt tgtacatgga tatttgattt cttttcctcg
    13381 accgtgacag acatcacagg ttacttggcg acgcatcata ccaagaggag tctgcgtatc
    13441 gacgttaatg acaccagcgc catgacagcg tccacaagtg actggacttg tccctggctt
    13501 agcaccagag ccattacatg tacgacagcc agcttcacga tgatacttaa cttccttctc
    13561 agttccgaag atagcttctt caaaggtcaa attgacacga tactggagat catctccttg
    13621 gcgaggagcg tttggattgc gcgaagaacc gcctccgccg aagaaacttg agaaaatatc
    13681 ctcaaaacca ccgaagccac ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa
    13741 accaccattg gcgcctgcag caccatactg gtcataggca gcacgttttt ggtcgtcact
    13801 caaagtctca taggcttctt gaacttcctt gtacttgtcc tcagcaccag gctccttgtt
    13861 gatatctggg tgatattttt tggaaagctt acgataagcc tttttgattt cgtctgccga
    13921 agcgtttttg gataccccca gacgatcata aaattcagta ttgttcataa ttcaagatac
    13981 aaagggcgtc aaacggacac agccatctag gagttttgac gacggacgct tacgtcctag
    14041 aaaaaactat ctttttggca cagtccgtag cccgtgttca gttacgaaca cccttattcc
    14101 tttctattga tgttctgaat cgaaccacca tttaggtcgg attcaattcc tttcttttat
    14161 atttagtaag aaattctgaa acccgtgttc agttacgaac actctttgtt cctttctatt
    14221 gatgagacaa aacccaaaca aataagattc cgtccctttt tatcgaaaaa cagaggctgg
    14281 gttgcaacct ctgcaaataa gtaaattaac tttattttga ttttaaatat cctataagta
    14341 cagaaatatt tatatatttt tgtctcttct tagtatttgc tatataattc caattgatca
    14401 taagaaatac aactactgtc caaatcatac caattatgaa cggtattaca aatttatatg
    14461 tttgtatttc taatgatatc atagctgata ccagcgccga tacaaatgca gacaacaata
    14521 ctgaggtaac aaaattcctt accgcttcat catttttgat acaactatca tgttcagcta
    14581 atataatttc tctatatcta gctaaatatt ctattggaat attatcaata aaatcttttg
    14641 atgttctata gttatcagct tgattacaaa aatcattata aacttttcgt gtatttttta
    14701 gatactcttc atccaataca ctcgtcttac ttttccgtaa actctccgtc tacgacgtca
    14761 tcgcctgcgt ttcctgttgc ttgtgcgcct tctgctcctt cttgagcttg ttgcgctgct
    14821 gcggcttgtt cgtagagttt aacagcaagt ccttgagctt tttcgttcaa tgcttcaagt
    14881 ttcgctttca tgtcgtccaa gttgttgtct tcttgagctt tcttaaggtc atcaagggca
    14941 gcttgggcag cgtcacgttc tgcgtcgaag cctttacctt cagtttcctt gattgtcttt
    15001 tcagtcgcaa agattgcttg gtctacttca ttacgaaggt ctacttcttc tttacgtttc
    15061 ttatcggctt cagcgtttgc ttctgcatct ttcatcatgc ggtcgatttc ttcgtcagtc
    15121 aaacctgagt tcgattggat gacaatagtt tgttcttttt gagttccaag gtctttggcc
    15181 ttaacagaca cgataccgtt cttgtcgatg tcaaatgtta cttcgatttg aggaattcca
    15241 cgaggtgcag ctgggatatc agtcaattgg aagcgtccaa gagtcttgtt atctgctgcc
    15301 attgggcgtt caccttgaag aacgtggata tcaacggctg gttggttgtc tgctgctgtt
    15361 gagaagactt gtgatttaga tgttgggatt gtagtgttgc gatcgataag ttttgtaaat
    15421 actccaccca ttgtttcgat accaagtgac aatggcgtta catccagaag gacaacgtcc
    15481 ttgacatcac cagtaatcac accaccttgg atagccgcac ccatagcaac tacttcatca
    15541 gggtttactg atttgtttgg ttctttacca gtttcagctt taacagcttc aacaacggca
    15601 gggatacgag ttgaaccacc aacaaggata acttcgtcga tttctgacaa gctcaaacct
    15661 gcatctgaaa gggcttgacg aactggaact tttgtacgtt caacaaggtc acgagtcaaa
    15721 tcgtcaaatt tcgcacgagt caaagtcatt tccaagtgaa gaggtccagc ctcacctgca
    15781 gtgataaatg gcaagctgat ttgtgttgaa gttacaccag aaaggtcttt cttcgctttt
    15841 tcagccgcat ctttcaaacg ttgcattgcc atcttgtcag tagacaagtc gataccgttt
    15901 tctttcttga attctgctac caagtggtca atgatttttt ggtcaaagtc gtcaccacca
    15961 agtttgttgt cccctgcagt tgacaatacg tcgaagacac cgtcacccaa ttcaaggata
    16021 gagacgtcga atgtaccacc accaaggtca aataccaaga ttttttcttc tttgtcagtc
    16081 ttgtccaaac cataagcaag agctgctgca gttggttcgt taacaatacg ttctacttca
    16141 agaccagcaa ttttaccagc gtcttttgtt gcttgacgtt gagcgtcgtt gaagtaagcc
    16201 ggaactgtga taacagcttt ggttactttc tcaccaaggt agtcttcagc gtagcctttc
    16261 aagtattgaa ggatcatagc tgagatttct tgtggagtgt attcttttcc atttgcagaa
    16321 actttttcag aagttcccat cttagatttg atagagataa ctgtatctgg gtttgtgact
    16381 gcttgacgtt ttgcagcatc accaacgatg atttctccgt ttttgaatga gactacagat
    16441 ggagttgtgc ggtttccttc tgggtttgcg atgattttgc tttcagttcc ttcaagaact
    16501 gcaactgctg agtttgttgt acctaagtca ataccgataa ttttagacat gtgtttttct
    16561 ccttgttagt taattttcta tttttctttt tgatactctt cttaagtggc gacgccgtca
    16621 gagcttgact tcgtcaatct ctttgactaa actttgagcc taaggtctca aaatttgcgc
    16681 aaatagcgcc acggcgaaga gtatcgtctt tggttcgctt cgctcactat tacaaagcca
    16741 aacatatttt atctttcttc atagtttatt gtcgtttcgg acaagttttc tattatgtaa
    16801 attgcgacac gaggagtcga aatcgatttt atttcgacga cgagttagta aggaagctag
    16861 acaaacgcca tagcgattgc cgttttctga cgagttgctt tagctaccgt cagaattgcc
    16921 gaatcgaaca cgccctaagc tctgagtaaa aaagatagat tttcttgtgt tcatcgaaca
    16981 cttcgtcaat ctcctatttt tactgcgggc tttgtatctt agttatacac cactaccatt
    17041 gctgggcgta ggatgcggtc atggagtttg tagccttttt gaaagacttg ggcgatggta
    17101 tctactgggt gttcatcgtc tgctgggaga gtttggatgg ccatatggta gttatggtca
    17161 aattcgccat ctgctgcgat ttcttcaatt ccttcttctt tcaaagcgtg aatcaagctt
    17221 tcttgcacca tccccaagcc cttcttcaca tcatctgtca aaccttcaac tgcaagtgca
    17281 cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca agtcctggct acgataacgt
    17341 tgcaagtttt gacgttcttc attggcacgg cgttggatat tttgcatttc tgcatgagcg
    17401 cgaagatatt tgttttcgaa ctcatctgca cgttcatttg ccaagtccaa ctcagacttt
    17461 tcaggagttg tttcttcagc tgtttccaca acttcctctt cttgaacttc ttctacttct
    17521 tcatttttta tatcttgggc catgttcgcc tcctttaatg atttcaatct taatgtactt
    17581 cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa cttcatggtc aaaacacggt
    17641 tgaccacatt gacttgattg attagctgtt ggtaatccag attaactgga ccgataatgg
    17701 ctagaattcc aactccccga taaggaatga ggaacttact actaatcacc gctaggtcag
    17761 ctaaacagga ctcttgaccg tctgcaacac gaacattttg catctgatcc tcacgcaacc
    17821 cctcacgaat ctccaaggcc accttttgcg gttggtcaaa gaactgatag gctgctagat
    17881 tggcaaaatt caagagattg accttgcccg ccatcacaat gttttcgttg aacatttcct
    17941 taaagatgtg ttcaaagaga tcgatgacat tatccgttgt tgtaaagtaa cgctggataa
    18001 tctgcggaat ctccgtccga atcttgtagt gaatatctaa aacggtgtga ccgaggaaac
    18061 gttcctgaat gatgctcttc agtttcagca aatcctcctg caagaagttc cttggaatca
    18121 gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa taccgccaag gctgtatgtt
    18181 gccccaaaac aacgatatca aaggctgtca aacgttgcct gctcggctca acatccagtg
    18241 ccactaccgt acagccactc aggtctgtta gcaagttagc agactcttgc agaatatcct
    18301 ccaatttgaa gaattcctga tcaaaggctt tgacaatctc atatacctca ttttcagcca
    18361 gtcggtcaaa atccagtgag tgtttcacat agtactgaaa accagcaaca cttggcatcc
    18421 gaccgcttga agtatgagcc ttctcaagca acccttgttt ttctagttcc gccatgtcat
    18481 tacgaatggt tgcactgcta gagttaatag actcttgcaa ggcttttgat ccgacaggtt
    18541 cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat atcctgctga cgctctgtaa
    18601 ccatctcatc actcctctct gtctgatcaa ttagcactca atgcatccaa gtgctaactc
    18661 atgattctat tatacaccct tagaagagaa tgtcaagaca aaaactcaaa aaattagcac
    18721 tcttttatca agagtgctaa aaatcaatct gaagacctag aaccttgcta ttcatctact
    18781 cggtatttcc tttttagtct gaaataacca taaattagat aagaaatcag aaaagcatat
    18841 aaaacaaaaa taagaaagaa agacatagaa agatcctctc taaacaaact catacaaaca
    18901 acaagaccac ctaagaaagt agctgtacag gaacgaagtc tagatcgcat aacttcccat
    18961 ttgagcccct tactcatata gacttgatcc tctggaagta aatcagaaga cgatttacga
    19021 agaatcgaac aagaacctgc tcctatcaat tcccaacctc tatctctaaa atcttgcagt
    19081 tcatgcttat attttttaag aaatctagaa tcatagatac ggtagatgac atcgtctggt
    19141 tgaccttgct caaaatagaa caaaccaaaa caactcgttc tatacctcca acctttcaaa
    19201 tgcatctcat gtaaatattc ttcttccttg tccaaatcaa caatggtgaa aatccgaaat
    19261 tctactctgc tattcattgt cttaccccaa aattagaaaa catgcctggc gttatttatt
    19321 agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct gaatcgcaaa
    19381 aactatcaat aaaacccaat ctattatgaa aatcaaaaat actccccaac tgaaagaact
    19441 acctccagtg acaaactttg agaaaaccgg tagtagagct aaaaagagaa gcaaaatagg
    19501 aagcatccgc attgttaaaa tccgtttggc ataaaaaatc tttatttaaa cgaaaatatt
    19561 atggcaaaat ttacgccagt ttttgaacgg ctgatgtaga tattttatac tttcaaaatg
    19621 tttaaatgtg attatttatt tttgaaaaat agctcaccag cccgactgaa agtgcttata
    19681 gaatgataat aagtcgcctg ccgaaaacag cgaaaaatag cggtgttatg cggagataat
    19741 ctgacgcgat gcgaaagtat attgcatact tattttcaac aatttagcag agtattttta
    19801 taagtgtgat ataatagaag tataatttgt tctgatagtt tattttatgg agaagtagat
    19861 ttttagaatg cggagggttc aatatggttg agtttataaa gtctaagaaa gaaatgagtg
    19921 aggaggatat taaagcaaat ttcatcactc ctgctattgt atccaaagga tggaaaaatg
    19981 gtgagcatat cgcttacgaa gaatacttca ctgatggtcg aattgaagtt agaggagata
    20041 aggctcgtcg taaagaagga aaaaaatcag actattcact gtattaccaa tttggaactc
    20101 gaattgcaat tgttgaggca aaggataata aacacagcgt tcgagcagga ttacaacaag
    20161 ctattgaata tggagagatt ttagatgttc catttgttta ttcttcgaat ggtgatggct
    20221 ttattgaaca cgaccgtatc acgagagaag aacgtgagct ggagttagac gaattcccta
    20281 ctcgtgaaga attattttct cgtatgacga aggaaaaagg attgacgtac gaaattacag
    20341 aagctatctc aactccatac tatacagacg ccttctcaat gaaaacgcca cgctattatc
    20401 agcaaatagc tatcaaccgt actattgaaa cagttgccag aggacaaaaa cgagtaatgt
    20461 ttgtgatggc aacaggaacg gggaaaacgt tcatggcttt tcaaattatt catcgccttc
    20521 gaaaagctgg tttggctaaa cgagttttat tcttagcaga tagaaacatc ttagtagacc
    20581 aaacgatggc tgaagacttt aggccattcg aaaaggtaat gacgaaaatt acaccaaaac
    20641 ttttgactgc tcctgaaaaa ttaaattctt ttgaaattta tctagggctt tatcagcaac
    20701 taactggtga agatggaact gaaacacatt atcaaaaatt tgacaaagac ttctttgatt
    20761 taatcgtaat tgatgaagca caccgtggtt cagctaagga aaacagtaac tggcgtaagg
    20821 taattgatta tttcagttct gcgacacaga ttgggatgac cgctactcct aaagaaacca
    20881 agaatgcttc caatacggaa tactttggtg agccaatcta tacttatagt ttaaaacagg
    20941 gaatcgagga tggttttttg gctccatatc gtgttatgag ggttaattta gatgtggatg
    21001 tggatggtta tcgtccagaa actggaaaag ttgatgctaa cggacaatta atagaagata
    21061 ggtactacgg caggaaagat tttgataaaa ccattgtcat tgatgataga acgcaaagag
    21121 ttgccaagtt tgtttctgat tatatgaagc aaaacaatgc acgatttgat aaaacaattg
    21181 ttttttgtgt tgatattgac catgccgagc gaatgcgtgc tgcacttgta aaagagaatc
    21241 tagacttagt ccaagaagac tatcgttatg tcatgcaagt aactggtgac aacgctgaag
    21301 gaaaagctca actggataac tttatggatg tcaattctaa ttttcccgct attgtaacaa
    21361 cgtctaaatt attaacgaca ggagttaatg ctaaaacatg tcgtttgatt gttttagact
    21421 ctaatatcca atccatgact gaatttaaac aaattattgg tcgtggcaca cgtctttatc
    21481 ctcaaaaggg gaaagaattt tttacgatta ttgattttcg aaatgttacc aatttgtttg
    21541 ctgaccctga ttttgatggt gagccagtga aggtgctgga aacaggtgcg aaaacagtca
    21601 gtggttctac gcccggtttc gtagatgagg aaggtgaccc agtagaaaaa tatatcgtta
    21661 cagacaagca ggttaccatt cttaattcta ctgttcaagt attggatgaa aacgggaaac
    21721 tgattaccga aagcctgacc gactacactc ggaagaatat cttaggtagc tacgccactt
    21781 tgaacgattt tatcacagtt tggcatacgg cggataaaaa gaagcttatc ttagacgaac
    21841 tttataaaaa aggagtttat ctagatgcta ttcgagagtc ggagggaata tcagaacaag
    21901 aaatcgatga ttttgattta ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa
    21961 cggaacgtat caataaactc aaacaaagcg gatatttata taaatatagt gaggaagcgc
    22021 gtgctgtttt ggaaatttta ctgaacaaat acatggataa aggtattgga gaactcgaaa
    22081 gcattgaaac attaaaactt ccagaatttc agatatatgg tggaaccttc aaaatcatca
    22141 atacttattt tggagataaa aaacgatatt tacaagcaat taaagaattg gagcaagagc
    22201 tatttacagt agcttaatga aaggaaagta tgtcaattac atcatttgta aaaagaattc
    22261 aagatatcac tcgaaacgat gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt
    22321 cttggttatt attcttaaaa atttatgata gccgtgaaat ggtttgggaa ttagaagaag
    22381 acgagtatga gtcaattatc ccagaggaat taaaatggcg aaattgggct catgctcaaa
    22441 atggggaacg ggtattgaca ggcgatgaat tacttgattt tgtcaataac aagttattca
    22501 aagagttgaa agagcttgaa ataacttcaa ttatgcctat tcgaaaaacg attgttaaat
    22561 cagcttttga agatgcgaac aactatatga aaaatggcgt cttgttacgc caagtcatca
    22621 atgttattga tgaagttgat ttcaatagcc ctgaagatcg tcattcgttt aatgatattt
    22681 acgaaaaaat tcttaaagat attcaaaatg ctgggaactc aggagaattt tatacgccac
    22741 gtgcagcgac tgattttatt gccgaagttc ttaacccaaa acttggagaa tcaatggcag
    22801 accttgcttg cggaacagga ggcttcttga cttcgactct gaaccgttta agtagtcaac
    22861 gtaaaactag tgaagatacc aaaaaatata atacagctgt ttttggtatt gaaaagaaag
    22921 catttcctca tcttttagca gttacaaatc tgtttcttca cgaaattgat gaccctaaaa
    22981 ttgttcatgg aaatacttta gagaaaaatg ttcgtgaata tacggatgat gaaaaatttg
    23041 acattattat gatgaatcca ccttttggag ggtcagaatt agaaacaata aaaaataact
    23101 ttccagcaga attacggagt tctgaaacag ctgatttatt tatggctgtc attatgtatc
    23161 gtttgaaaga aaatggtcgt gttggagtta ttttacctga tggttttcta tttggtgaag
    23221 gtgtaaaaac tcgcttgaaa caaaaactgg tagatgagtt caacttgcat acgattatta
    23281 ggttgcctca tagtgtcttt gcaccgtata caggaatcca tacgaacatt cttttctttg
    23341 ataaaacaaa gaaaacagaa gaaacttggt tttatcgttt agatatgcca gatggttata
    23401 aaaatttctc gaaaactaag ccgatgaagt cagaacactt caatcctgtt cgtgactggt
    23461 gggaaaatcg tgaagagatt ctggaaggta agttctacaa atctaaatca tttacaccta
    23521 gtgaattggc tgagttgaat tataatttag accagtgtgg ttttccaaaa gaggaagagg
    23581 aaatcttaaa tccctttgag ttgattcaga attatcaagc ggaaagagca actttaaatc
    23641 ataagattga taatgtatta gctgatattt tgcagttgtt ggaggacaaa taatgacacc
    23701 agaacaactt aaggcaagta ttctccaaag agcgatggaa gggaaattag tgccgcaaaa
    23761 tcccaatgac gaacctgcaa gtgaattatt aaagagaatt aaagctgaaa aagaaaaact
    23821 tatcagtgaa ggaaaaatca aacgagataa aaaggaaact gagatatttc gtggtgatga
    23881 tgggaaacat tatgggaagt ttgctgatgg aagtactcaa gaaattgatg ttccttatga
    23941 tattcctgat acttgggagt gggtgaggtt ttctacattg gttgaaattg tcagaggtgg
    24001 ctctccacga ccaatcaaag attatcttac ttctgaagta gatggaataa attggataaa
    24061 aataggtgat actgaaaagg gtgaaaagta tataaataat gttaaagaaa aaatcaaaaa
    24121 atcagggctt aacaaaacta gatttgtaaa aaaaggtaca tttttgttaa ctaattctat
    24181 gagttttggt agaccttata ttttgaatgt tgatggtgca atacacgatg gatggttggc
    24241 tatttcgaac tatgaaaact cattaaataa agattaccta ttctatattc tttcatcaaa
    24301 tgtagtttat tctcaatttc tatctctaat tagtggagct gttgtgaaaa acttgaatag
    24361 tgataaagtt gcttctattc ttatccctct ccccccacta tccgaacaac aacgcataat
    24421 agaagcaatc gaatcagctt tagaaaaagt agatgaatat gctgaaagtt ataatagact
    24481 agaacagcta gataaagaat ttccagataa actaaaaaaa tctattcttc aatatgctat
    24541 gcaaggaaaa ttagttgaac aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa
    24601 aatacgagca gaaaaacaaa aactctttga agaaggcaag attaaaaaga aagatttgga
    24661 catttctatt gtttcccaag gagatgataa ctcttattat gaggaagtac cttgtgaaat
    24721 accagaaagt tgggaatggg tgaggttaaa cgatataacc tcctacattc aaagagggaa
    24781 gtctccaaaa tattcaaata ttcctatata ccctgtgatt gctcagaaat gtaatcaatg
    24841 gtctggcttt tctattgact tagcaagatt tattgatccc gaaacagttc atagttacca
    24901 gaaagaaaga ttactaagag atggtgattt aatgtggaat tcaacaggtc taggtacgtt
    24961 aggacgatta gctatttacc atgaaaataa aaatccttat gcctgggctg ttgcagatag
    25021 ccatgttaca gttataagag tcttatcggg ggttattaat tgccatttca tctataattt
    25081 tctttcctct cctattgttc agtcagttat tgaagaaaaa gcgtcgggta gtacaaaaca
    25141 aaaagaatta ttaacgaaaa ctataaaaga atatttaatc cccctcccac cccttcctga
    25201 acaatccaga atcgttgata aaatcgaaca atttttcgcc catattgacg cactaattta
    25261 gtataatagt tttacgtgcg gtggaatttc tatcaaacat aagataggag ttttacgttg
    25321 aaagattttg aattacattt gaagaaagct ggtttagctg aaaatactgt gcgttcgtac
    25381 ctttatggtg ttcgattttt cttggagaat tacgaactca aaatggaaga tttatttgaa
    25441 tacaaaggat atttattaga caattttaaa cctaaaactg tcaatttgcg actacaagga
    25501 gtaaataaat atctggcttt tattggtcat gatgatttga aattaaaatt tgtcaaagta
    25561 cagcaaaaac cgtttttaga agatgtcatt agccatgctg attacctttt tcttaaacgt
    25621 agtttgaaaa aagatggtat tttaaaatgg cattttgtcg tttggttttt aggtgcaact
    25681 ggggctcgtg taagtgaact tattaaacta aaagtagagc atgtagaaat cggttatttt
    25741 gacatttact caaaaggtgg taaaattcgt agactgtaca ttcctaaaaa attaagaaat
    25801 agttgtctta gttggttaga atcagaaaat cgtcgaagtg gttatttatt tttgaataaa
    25861 tttaacgaac caattacagc aagaggagtt gctcaacagt taaaaaatta tgctgataaa
    25921 tacaaaatga atcctaaagt aatttaccct cattctttta ggcatttatt tgctaagaat
    25981 tttttagcga agtataatga tattgccttg cttgcagatt tgatgggaca cgaaagtata
    26041 gaaactactc gaatttatct aaggaaaaca gctactgaac aacaaaatat tgtagataaa
    26101 attgttaatt ggtaaaaaat aacaggtggt caaactgact acctgctatt tttgtgatta
    26161 tggctcttat tatgggaata aagacgaaac aacctcttat cctatatatg aaatcccaga
    26221 agcatggaga tatattaaat ttgctagcct agttaacttc agaataggaa aaactcctcc
    26281 acgcagtgaa gctacttttt ggggaactga aataccttgg gtatctatat cagatatgcc
    26341 tatatctggt tatgtaacta atacgagaga atctatttct aaattagcat taaaatcaaa
    26401 gaaaatagac atttcaccta aaggaacttt attaatgagt tttaaattat ctattggaaa
    26461 agttgccata ttggatattc ctgccactca taatgaagcc attatatcga tattccccta
    26521 tgctaataaa gaaaatatta tcagagatta cttaatgata tttttgccac ttatctctac
    26581 tttaggtgat tcaaaagatg ctatcaaagg gaaaacatta aatagtacca gtatctccga
    26641 attattaatc cctatttcta atcatgaaga gatgaaaaga atcatttcca aagttgattt
    26701 actttttcaa aaagtttctc aactttttga gtaataagtt cctgttcctc aaaaggagct
    26761 aacggaatta atagctcgct tagtgtagtt ttaggaatat tatataaagc ttgacctgat
    26821 agtttagtta ttgctttcaa ttgtttataa aataacggag aggacaagtt aaataataga
    26881 aattttgaaa taatctctga actttcgaat ggtgttaatt ggaaaataaa tccaccagcc
    26941 acaacaccat catagtcttt atcgattctt gcaaactttc caatatgttc taaagaggtt
    27001 gatacaggtg ttattagctg attatgtttt aaataaactt gctcagagga gatgaattgt
    27061 gtatcaatgt agtaatcatt atccaacaga gaaaattcta aaggcttaat attaccacca
    27121 cgtataattc taacaccttt attattaatg cttaaatcgc ccttcttgta agaaagacct
    27181 gtattcattg aaaaaatatc ttttattttt ataacaaccc aattcatagg t
//
LOCUS       DAVHSL010000030        23528 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000030 DAVHSL010000000
VERSION     DAVHSL010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.030"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..859)
                     /locus_tag="VVR39_001277"
     CDS             complement(<1..859)
                     /locus_tag="VVR39_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6030768.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFT"
     gene            complement(872..1611)
                     /locus_tag="VVR39_001278"
                     /pseudo
     CDS             complement(872..1611)
                     /locus_tag="VVR39_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(1633..2457)
                     /locus_tag="VVR39_001279"
     CDS             complement(1633..2457)
                     /locus_tag="VVR39_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6030769.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQHIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(2594..3808)
                     /gene="thiI"
                     /locus_tag="VVR39_001280"
     CDS             complement(2594..3808)
                     /gene="thiI"
                     /locus_tag="VVR39_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU6030770.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(3817..4959)
                     /locus_tag="VVR39_001281"
     CDS             complement(3817..4959)
                     /locus_tag="VVR39_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6030771.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDKKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFEIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            5097..5525
                     /locus_tag="VVR39_001282"
     CDS             5097..5525
                     /locus_tag="VVR39_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030772.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPTTPTSENNTQ"
     gene            complement(5676..7901)
                     /locus_tag="VVR39_001283"
     CDS             complement(5676..7901)
                     /locus_tag="VVR39_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6030773.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDITTVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMESRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(8065..10017)
                     /locus_tag="VVR39_001284"
     CDS             complement(8065..10017)
                     /locus_tag="VVR39_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030774.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(10014..10925)
                     /gene="pfkB"
                     /locus_tag="VVR39_001285"
     CDS             complement(10014..10925)
                     /gene="pfkB"
                     /locus_tag="VVR39_001285"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU6030775.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(10922..11662)
                     /locus_tag="VVR39_001286"
     CDS             complement(10922..11662)
                     /locus_tag="VVR39_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6030776.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            11824..11911
                     /locus_tag="VVR39_001287"
     tRNA            11824..11911
                     /locus_tag="VVR39_001287"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11858..11860,aa:Ser,seq:gga)
     gene            complement(12094..12441)
                     /gene="ssrA"
                     /locus_tag="VVR39_001288"
     tmRNA           complement(12094..12441)
                     /gene="ssrA"
                     /locus_tag="VVR39_001288"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(12975..14084)
                     /locus_tag="VVR39_001289"
     CDS             complement(12975..14084)
                     /locus_tag="VVR39_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6030777.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            14187..15428
                     /locus_tag="VVR39_001290"
     CDS             14187..15428
                     /locus_tag="VVR39_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU6030778.1"
                     /translation="MKKTFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(15627..17039)
                     /gene="sufB"
                     /locus_tag="VVR39_001291"
     CDS             complement(15627..17039)
                     /gene="sufB"
                     /locus_tag="VVR39_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU6030779.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(17093..17533)
                     /locus_tag="VVR39_001292"
     CDS             complement(17093..17533)
                     /locus_tag="VVR39_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU6030780.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(17520..18746)
                     /locus_tag="VVR39_001293"
     CDS             complement(17520..18746)
                     /locus_tag="VVR39_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6030781.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQNLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(18757..20019)
                     /gene="sufD"
                     /locus_tag="VVR39_001294"
     CDS             complement(18757..20019)
                     /gene="sufD"
                     /locus_tag="VVR39_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU6030782.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(20047..20817)
                     /gene="sufC"
                     /locus_tag="VVR39_001295"
     CDS             complement(20047..20817)
                     /gene="sufC"
                     /locus_tag="VVR39_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU6030783.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(20967..21161)
                     /locus_tag="VVR39_001296"
     CDS             complement(20967..21161)
                     /locus_tag="VVR39_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU6030784.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(21189..22844)
                     /gene="dnaX"
                     /locus_tag="VVR39_001297"
     CDS             complement(21189..22844)
                     /gene="dnaX"
                     /locus_tag="VVR39_001297"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU6030785.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(22844..23341)
                     /locus_tag="VVR39_001298"
     CDS             complement(22844..23341)
                     /locus_tag="VVR39_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU6030786.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
BASE COUNT         7021 a         5219 c         4410 g         6878 t
ORIGIN      
        1 tggtaaaacc acctgcaggg cggttattgt actcgatggt aatataatcg tccccctcac
       61 ggaagaactc aatatggaaa aaccgttctt tcataccaaa ttctttgaca attgcttccc
      121 catacttgcg cagtttagga tccatatcct tgagcacata ataagaattg tccatcttat
      181 aaatcatgag gtcaagcggt gtataggcgt agtcaaaggt tgttgagaag acaatctttc
      241 catccttgtc cacgagcccg tcaaaggtac agatttcgct ggaagtgaca aatttttcaa
      301 agaaataaag ggttgaatgg tcccattctt gcttgaagtg attgatatcg tcttctgtct
      361 caagtttaaa ggttgcggct gctcccactc cattatcagg tttggcaatc attggaagac
      421 cgatttcttt cactgcttga tcaacatctg cttccgtctt gataacagct ccaggtacca
      481 caggaacacc tgcttttttg aaaagtttct tcatttcaga cttatatttc gtctttttga
      541 gatcctctgg tttggcacca aaaacattga attgttctct gagtgttgcg tctagctcaa
      601 gccagtattc attgtgagac tcgatgcggt caattggacc atgtttataa aagagaaaag
      661 caactgcacg tttgacttca tctatgttct caagattatc aacacgaaaa tactcggtca
      721 agctattgcg caagggctca tccaattgct cgtaagactc ttgaccaatt cccaagactg
      781 tgatgccttt attagctagt tcgatggtaa actgttgaaa gttttgtgga tagtagggag
      841 aaataacaag gtaattcata ggtaactcct tttataaata gagattaccg aggaaataag
      901 gcatttgttt acgccaccat tcccagtcat gggcgacatc atgtccccat tcagcaaacc
      961 aggctggaat ttgtttcttg tcaaaggctt ctttgagctt gtaaaaggat gacaaaccat
     1021 cttgttccca ggctccaagc cccgtacaca gcacaatctc tgcctgacgg taacggtcaa
     1081 taaaccagcc gtcgttttgg ttccaaatat aatctactgg cgagttttgg taaatagcat
     1141 catcgttgta gtaatcaccg ataaagaaac gtgcgtcgta aacaccactg agagcaatca
     1201 ctttggtaaa gacatctgga tgctggagga agaaattgag tgcatgatag gctcccatag
     1261 agcaacctgt cgtcatcatg ccataaaacc aacctgtctt gtgcttgata aaagaatggc
     1321 ctcctcaatc acataacatt cgtaggcacg gtgcatttcc gcttggtcat gagcattttt
     1381 ccaagtagcc aaccagctct cactatccac actagatagg gtaaagaact ggacacggcc
     1441 ttcctcgata aaggaagcac aggcatcaat catgccaaaa tcatagtatt cgttgtgact
     1501 accacctgat gaagcaaaga ccacaactgg aatcccacca tgtccataac ggttaaggta
     1561 catttcacgg ttaggatgac cactccagtg gctaagatgt tcaatatgca tttcgttttt
     1621 tcctttctta acttaccatt tttctgcaaa aaatctcaga caatctggta gattttctga
     1681 ccaagggatt tcactatgga tggcaccaga ctgaactttt agcacaagat tatccagatg
     1741 tactccccct gctatcaaat catggtaata gcaaagcgac gagtcgatat aggcttgttt
     1801 gatattgcca tccatcaagg tcttgtctgt atcatctgct tcttctgttc ctacatagat
     1861 gaagatgtgc tggtcaggcg atagtttctg gcactcgata tagcggttaa aggcttcttg
     1921 gtggagccag tttgcagatg aaaaaacgcc caagcaacca atttggtctt ggtattccaa
     1981 accgataaac tgggtaatat tgcctcctag tgaggaacca atcatagccg tatgctggca
     2041 gtctgctttt gtacgataag tctcatcgat aaaaggcttg accacctcca tgacaaactc
     2101 agcatactcc acacccttac caccaaactg ctgctctggg ataggagatt cttggaactt
     2161 ccaagccgca tactcattca ttcgccccat accatcattg tcaatagcaa cgacaatcat
     2221 gcgactgata tccggatttc gtttgatagc tggaataatc ttccatgaat atccaatgaa
     2281 agactctttg ctataaaaaa cattttgccc gtcatgaaag tatacaacag gataggaacg
     2341 gtctgtatct ttctcataat ctttaggaag aagaatacgt acacggcgct ccttacctgt
     2401 ataaggaacc ttgagtttgt gttctttcat ttttagataa aagtaggatt gattcattgt
     2461 cagaaaactc tctatattca aaattttata tcattatatc atgaaaatag aaaaaagtta
     2521 gttttttacc tgtttttaga aaaaaaaact aacttttttt actgattttc gctattcttt
     2581 tggattttct gaattagagt agattatcaa tcaagtcatc aacttcatct ttttcggctt
     2641 gaggtgtgat ttcagtaatc atgattccag ccactgctcg ctcaaccaag ccttcaacat
     2701 ccatacgcgc ttcgtactgc tccgcattct taattttagg atttgttttt ggacgatctg
     2761 gtgcaaaaat ggtacaacag tcttcaaacg gttggattga aatgtcaaag gtatcgattt
     2821 cctgggcgat gtcaatgatt tccaacttgt ccatggtaac cacaggacga atgatgggag
     2881 tgttggtaac agcattgata gccttcatac tttcaagggt ttggctggct acttgaccta
     2941 gactttcccc attgatgata accaaaccat ttcgtacctc acgaatacgg tcagtaatcc
     3001 gcatcataaa gcgacgagtt agagtcatca aataagcttc tggcgctttg gctttgattt
     3061 cctcttgaat ctctgtgaaa ggcacctcga taaactggat atttccgcca aacttggtca
     3121 atttacgggt caagtcctgc gctttcttga gggcaccagg actagtatat ggtggactag
     3181 caaagtgaac tgcctcgata tccaccccac gcttaagagc aagataacct gctacaggtg
     3241 agtcaatccc tcctgacaac atgagcatcc ctttacctga agttccaact ggcaaaccac
     3301 cagccccacg aatggtttca taagaaagat aggctgcttc ttcacgaatc tccacctgaa
     3361 gattgatgtc aggacttttc atttgaactt gcacatttgg aatggcttcg aatacagccc
     3421 ctccaagtgt ttggttgagt tcacgactat caagttcaaa gttgtggtcg ctacgcttgc
     3481 tagaaatctt aaaggtcata ccttccttgt agatgtcccg cataatctct tggacagcag
     3541 acttcaaaac ttctacagat ttttcaacct tataaacagg agaaaagttt tgaattccaa
     3601 aaacttgttt gagagattct gcaactgctg tgtaatcagc tccattgagg taagcgtggg
     3661 cacggtcgcg atctgctgtt accttaactt ggggatagat agacaaaacg tctgaaatat
     3721 tattgcgaag tttattgatg aaacgcatac gatttttgcc cttggttgac agctcaccgt
     3781 agcgaatcat aatttctgaa tactgcatga atgctcctat cttacttttc tagtttgatt
     3841 gtaaattaat tttagcttgg tcaagaactg ctcgacctga ctcatatcat tttcaaggtc
     3901 tagactaaga cgcacagctg actgagcctt atccttgtcc actcccatag caatcagggt
     3961 tccggctggt ttcccagcct tggacgaaca agccgaggtc gttgagatga aaatatcata
     4021 gtcttcaaag gcgtgaacaa tgacctcacc acgaacaccc ttgatttcaa aagtcagaat
     4081 atgaggggcg aagtcttcct catctgaaaa gacaaatata tccggatagt ccagaagtgc
     4141 ttgacgaatc actgccttca tctgcccagt cttgctccta aagatatcta gcttttccat
     4201 agataaacgg agagccttag cggtcgctgc aattcctgcc acattttcag ttgtcgaacg
     4261 gtaatcacgt tcttgaccac cacctgttaa aagaggcgta atcttcttgc cagacttgat
     4321 atagataaaa ccaacaccac ggattccgtg gaacttgtga ccagagaaag tcgcgaaatc
     4381 cactcgttct gtcagatact tttcagtcgg aatcttggca agcgcctgaa ccgcatcaac
     4441 gtggaaggaa atagttggct tgtctgccaa tagttttgaa atagcctcaa tgggctgaac
     4501 agagccaatt tcattgttaa ctgccatgat ggaaacgagg gtcgtatcag gtcttatcaa
     4561 atcttctagc gcctcaacat ccacaaatcc tttcttatca actggagcaa aatccacttc
     4621 aaaaccttga gctttcaacc agagggctga ttccttaact gctggatgtt caatggctga
     4681 tacgatgatg tgcttgccaa actgggcttt ttcaaatgct actcccttga tgatccagtt
     4741 atccccttct gtcccaccag atgtaaagaa gatttcatca cttttcttac cgattaaatc
     4801 tgcaatctgt tgacgggaag catctaaaat tcgtgttgcc tggtctccca aacgatggag
     4861 actagatgga tttcctaaaa tttttgaagc cacctgcata taggtttcaa gggcttctgg
     4921 atagggcctg gtcgtcgccg aattatcaaa gtaaatcatg tttctcacgc tttctaaaat
     4981 cactccttct attgtatcat gaaacggagc ttgcgacaag aaagggcaat ttctcttttt
     5041 ttaagatttt tttaaagaaa cagagtataa taagtcataa tcaaaggaga gaatgtatgt
     5101 ctaactatcg tagaacttca aaaccgaaaa cagaacatat caaaaaaggc tttactgttt
     5161 ttcaaaaaac cattactact atcggtagta tccttggttt gattacagcg ggtatcacga
     5221 tcatgaacgc cttggataat aataataaaa atactaaaaa agaacctacg acaagccaga
     5281 cgacaacctt tgtcaaagaa attcaaaaag aatcccctca ggaaaatact actccaaata
     5341 aggaaaataa cacttctcaa gaaaaaacac aacaagaaga aacgccaaaa tctagcgtca
     5401 aggaagagaa aaaagaagat cagaaaacag caactcagga ctctactaca cctgctacaa
     5461 gtaaacctgc cactgaaaat gaaaaacagc ccactactcc aacttcagaa aataatactc
     5521 aatgaaaatc aaagagcaaa ctaggaagct agccgtaggc agtacttgag tacggtaagg
     5581 cgaagctgac gtggtttgaa gagatttgcg aagagtataa aagtaatcaa tagccagtaa
     5641 aatagctcct tccaaccttg gaaagaagct attttttatt gctgcaatac ttttcttggc
     5701 ttggtacctt cagctggacc aatgacacct gccatctcaa gctcttccat gagacgggtc
     5761 gcacggttaa atccaactga caaacgacgc tgaatcatgg atgcactggc tttctgtgtt
     5821 tcgataacca aagacttagc ttcttcaaaa agcggatcac caccagcatc tccatccgaa
     5881 aattctcctt cattttcaga aacctcacct ggatcaaaac tctcatcgta gtctgcatct
     5941 gcctgagcct tgatgaagtt cacaatgcgc tcaacatcgt catccgagat aaaggagcct
     6001 tggagacgaa ctggatgatt ttcatcaatc ggtttaaaga gcatgtctcc tcgaccaaga
     6061 agtttttctg ctccattttc atccaaaatc gtacgggagt ctgttcctga tgaaaccgca
     6121 aatgctacac gagatggaac attggcctta atcaaaccag agatgacatc aacagatgga
     6181 cgctgagttg caagaatcat gtggatacct gcagcacgcg ccttctgccc aagacggatg
     6241 atagcatctt ccacttcctt gctggccacc atcatgaggt cagccaactc atccacaatc
     6301 acgacaatga gtggtagcgg aatttgcttg tactcagact gggaattgaa ctcttctacc
     6361 ttggcattaa aacctgcaat attccgaact cccaccttgg caaagagttc ataacggctt
     6421 tccatttcat ccacaacctt ttgcagagcc ttgctggctt tgcgtggatt ggtcacgact
     6481 ggaatcaaga ggtggggaat atcattgtaa acagataact caaccatctt gggatcgacc
     6541 atcataaatt taacttgatc tggtctcgcc ttcatgagaa tgctagcaat aatgccgtta
     6601 actgctactg acttccctga acccgttgaa cctgcaacta gcaagtgggg cattttagaa
     6661 aggtcaaaag ctcttgcggt tccattaaca gccttcccta aaggaatttc caagaaattt
     6721 tctgctttcg tttgcgattg ttcccatagt tctcggaaag atacagtggt aatatcggag
     6781 ttaggcactt caattccgat tagggatttc ccagggattg gtgcttcaat ccggacatcc
     6841 ttggcagcca aggctagagc gaggtcatct gatagattgg aaatgcggtt gacccttaca
     6901 ccaacagccg gcttgacttc atacttggtc actgatggcc caatttcggc ccgttcaact
     6961 gttaccttaa taccaaagct agcaaaggtt gcttctaaga ttttgatatt ttctctgaca
     7021 attttcttct ctttagactg atcttttggt ttatctggtg caaagagttg taagcttgga
     7081 agtttgtatt caagggcttc tttggctgaa aaatcgacct gaacatcttc gtcatctgag
     7141 tcatcttcct gttcagggaa tttaagttca gcttgaggca ggatgatttc tggttccacc
     7201 cacttttctt ctggaatagg tggaagattt tgaacagctt cctctgtcag aatttcaccc
     7261 gtttccatat caacaggagg caaatcgagt aaggcttttt cagtctcttc ttgttctaat
     7321 ctagcctctt tctcagcctt ttggcgagct ttttcttctt gtttgacaaa gcgttcctct
     7381 tttcgacgct cgtgcccttc ccaccatttg gcaaagcctc tactgaaaaa ttcagcaata
     7441 tcgtaaacag accaagggct gactaggaga gaacccacta aaatcaagat agaaccaata
     7501 aagtaagttc cgatatttga aaagagaaag gctgttggaa tataaagagc gaccccgatc
     7561 aagccccctc cagcaaagct agtcgttcga aaaccagtca gatctgtcac aacctgagcc
     7621 atggtccctt ttagaacgga cttgtccaaa ccatatttcc aaaccaagta ggcctcaaaa
     7681 atcaagagta agccagcaaa tatggtgaaa aagccagata agagtccttc ctgttttcgt
     7741 atccacttga aaaagaagag atagattaat aggccgaata tcgccagata agctaggcta
     7801 cccactagca agcgaattaa attataaagg gttatacctg cagcccctaa tttgaaggct
     7861 gcgaaaatca ataaaatcgc aattcctaac gaaatcaaca ttcgttgaat cgcttctttt
     7921 ctttccagtt ctgctttaga cggtctccgt cttgttgtac ttgtattctt gtttgccatt
     7981 cttctattat accatatttc acaggcattt cgggaagaga aaaagactgc accaaacggt
     8041 ccaatctttt catttttcta ttttttatgc ttgtggtttg cgtaggtaac cataaaccac
     8101 accacttacg attgctccta ccaagacaga aacgaggtaa aggagagcat ttgaagtaag
     8161 ggcgataacg aagattcctc cgtgtggcgc catgagtttg ataccagtaa gaccaacgag
     8221 tccacctgct actgctgaac caaggatgaa gcttggaatc gcacgagctg gatcagcggc
     8281 accaaatgga atcgctccct cagtgataaa tgacaagccc atgatgatgt ttgtcaaacc
     8341 agagttacgt tcttccttag taaatttatc tttgaaaaga agagttgcga caaagattgc
     8401 aagtggtggc accattcctc cagccataac tgctgccatg gctacagaac cacctgaaga
     8461 aacagttgct gcaagcgtac ctgtaccaaa gacataagct gctttattaa ctggtccacc
     8521 catgtcaaca gccatcattc caccaaggac gataccaaga aggacagctg aacctcctcc
     8581 aagaccgcct aggaagtcat tcatagcagt gttgattgca gccattggga tattcacagc
     8641 tagcataaca aatcctgtca agattgttcc aagaagtggc aatagaagga ttgatttagc
     8701 accttcgagt gaacgaggaa ctttaacgta tttcttgatg gcaagaacca aggcacctgc
     8761 gataaatcca ccaacaaggg cacctaggaa accagatgag acacctgcaa gagttgaagt
     8821 tgcttcacca cctgcggcat aaggaatttt accaaaggca aaaccttctt tggcaatagc
     8881 accagccacg aaacctgcta ccaaacctgg tttttcagca atagagtagg caacataacc
     8941 cgcaaagact ggaagcatca aaccaaaggc agctccacca attttcatga acatagaagc
     9001 taactcatgg taagaaccaa gattgccaag gttttcattt ggaacactca aagcaccgtc
     9061 aatcaagaag gcaagggcaa tcatgatacc accaccgata acgaatggta acatttgaga
     9121 tacaccactc atcaagtgtt tgtagaaggc accaccaagg ctttgttttt cgttagaggc
     9181 tgttgcagct tttgcaccat tagcggcacg gtagacttca gtatctcctg aaagagccaa
     9241 gttaattagc tcttctgtct tacggatacc gtcagcaact ggacgattga tcaatggttt
     9301 tccatcaaat cgatccattt caacggcctt gtctgctgca atgataatag ctttagcctt
     9361 acggatatct tctgcagtta gttgatttcc aacaccgcta gcaccgttgg tttcgacctt
     9421 gataccaacc cccatttcag cagctacttt ttgaagggct tcttgggcca tgtaagtgtg
     9481 ggcaatacct gttgtacaag ctgtaacagc tacgataaag tcaccagagt cattagcagg
     9541 tgcttgaaca agttcctcag ttttttctga agcttggtca aaaagttcga taacttggtc
     9601 tgcagatgtt gcttgacgaa gtttgtctgc aaaaccgtct ttcatcaagt attgagacaa
     9661 ttctgccaag gctgccaagt gagtatcatt ggcaccttct ggagctgcaa tcatgaagaa
     9721 gaggtcagtt gcttgtccat ccaagctctc gtagtcaaca cccttatttg acttagcaaa
     9781 tagaactgtc gcttctttga cagcagcgtt tttgctgtga ggcattgcga ttccatcacc
     9841 caaaccagta gaagtcaaag cttcacgcgc caaaattcct tctttaaatg tttcaaaatc
     9901 tgttacataa ccgtgctctg tcaaattttt aatcatctcg tcgatgacag ctgttttttc
     9961 agttgcctgc aaatctagca acatgacatc ttttctcaat aggtcttgaa ttttcatctt
    10021 ttttctacct caacttttcc atatgtttct ttaataaatt ccgccgttgc caagtcatct
    10081 gagaaggtag ttgccgttcc gcaagccact ccccatttga aggcttctac tacgtctttt
    10141 gatttgacaa attcacctgt gaatccagca accatagaat caccagctcc aactgaattt
    10201 ttgactgttc ctttgattgg tttagcgaag taagctccct cagatgtgac aagaagggca
    10261 ccatcaccag ccatagagat aataacattt tgagcaccct tagccagtaa ctcacgagcg
    10321 tatttctcaa tttcatctaa actttcgagt ttaaccccaa aaatcgctcc aagttcatga
    10381 ttgtttggtt ttacaagaag aggctggtag tccaaactat caattaaggt ctgtccttca
    10441 aagtcacaga ccacttgcgc accagtctgg cgcgtcaagg aaatcaaatc cttatagata
    10501 acattgccta gatttttagc acttgaacct gcaaagacaa ctgtatcttc tgctgtcaga
    10561 ctagataaaa tagctttcaa ttcttctagc tgaaccgatt caacagttgg acccgttccg
    10621 ttgatttctg tttcttggtc tgctttgatt ttaacattga tacgagtatc ttctgccacc
    10681 tggacaaaac gtgtctcgat ttcttcctct gctaaagtat ctgtgataaa tttaccagta
    10741 aagccaccga taaatcccgt cgctgtattt ggtatattca aacgtttcaa gacacggctg
    10801 acattgattc ctttcccacc agcaaactta tcatcactgt ccatacgatt tacactacca
    10861 actttgactt ggtccaaacg aacgatatag tcaatggatg gattgagtgt gactgtataa
    10921 atcatacttc tattacctcc gttttctcct taataacctg caagagctca tgcccttgac
    10981 tagtgataac gatagcgcgt ttgagtggtg ctaccttggc aaagcaagtt tgtccaattt
    11041 ttgacgaatc caccaagacg taggtctgct tggcattctc caaaatagct cttttcacag
    11101 ctccctcctc catatcagga gtcgtataat agccatcgtc aacaccattc attccgataa
    11161 aggcacggtc aaagtgcaat tggttaatct ggttaagagc aacgcccccg atactagcat
    11221 ctgtcgccgt cttgacgttt cctccaacca tgacagttgg aatctgcttt tcaaccaact
    11281 gagcggcatg gtgaatggag ttggtcacaa ctgtaacatt cttattgacc aattcatgaa
    11341 tcaaaaaagc agttgttgtt ccagcatcga taaagatgac atctttttct ttaatgagag
    11401 aggctgcttt ctgagccagc aacttctttt cttgaaggtt tttgacagat ttttcttgaa
    11461 tggtttcttc ttcctgtaag gagtagggga gttctgctcc accatgcaca cgacgaagct
    11521 tgttttccgc ttccaactca tccaagtctc ttcgaaccgt tgattctgac gtttctagca
    11581 aactaactaa tttttctaga gaaactacat gatgctgatt taactcctct aaaattagtt
    11641 gtttacgttc tgtttttaac actgaatcac ctcctgttat cgtttacact attcattcta
    11701 tcatactttc tttcgaagtc aagcattttt tatcattttc tttcaaaatc tatcattttt
    11761 cttatttcta gaatttttat tgcaagataa gagcctttat ggtagactat ttgagtaagt
    11821 attggaagat tactcaagag gcttaagagg ccgtgttgga aacgcggtag gcgtgtaata
    11881 gcgtgcgtgg gttcgaatcc catgtcttcc gtggaaaaaa gattattttt aggatgcgac
    11941 aaatgttgta tccttttttc tatccttttt ttaaaatagg gtctgtttgt gactcccttt
    12001 ttagcaaaag aatgcaaagg aataccaaag ataaaaataa aaaacgttga tttaacaacg
    12061 ttttaccaag gaatgcaaaa gaatgcaaag gaataatgga gccggtggga gtcgaaccca
    12121 cgtccaaaca cctgccaaca tatttgtcta caaccatagg ttatgtatta ttttaacagc
    12181 ccctcgacac ataactcaag tctagaaact gcgagtctat caatctctta tcaagccgct
    12241 agacaaggct taatcgtatc tcgctaataa taagacctgt cattgaacac gagcaatcca
    12301 aatcgggtca cgcctgctgg tttttaggca gctagagcgt aagaagtgtt attttttgca
    12361 gttatattta actgagcgtt tacgtcgcca cacgagtcgc aaaatatgcc tcataatgcc
    12421 tgtcgaatcc gtaacgaccc caaaagacaa taaaaccatt ataccttatc taactcaaaa
    12481 atgcaaaaag aaatcacata cctaagatga agctatctgt tttgaagaaa ttcacgaaga
    12541 gaattattct aaaatacttt cagatgagaa ttttcgtact ctctttattt caattcattt
    12601 gagtttaaaa actataaaat caatccttat attattcgat ctacttttca cttattgcac
    12661 caaaatatag taaaatgaaa taagaataga acgaatagat aaggacagtc aaatcgattt
    12721 ctaacaatgt tttagaatta gaggtgtact attctagttt caatatacta taaataggtt
    12781 tcattcgaac tttaatagac tatgaaaacc agtggaactt accctgacac ggaattccac
    12841 tggttttttc gatttttatc agattaactt ctactattct tagctgtgaa aattagttta
    12901 agactttaac ttattttcag tcttctaatc taaaggccac ttccagtaaa gaaaaatcag
    12961 ggttctcctg acttttactt agctaattct ctttctcgtt ctttcattat tttatgattt
    13021 tcatacaaac gggataagaa cttagaaatt tctttcaaga tagaataggt tggcactgcg
    13081 acaatcattc caactacacc atagatattg cttgacaaca aaagtaaaac taaaatcgtg
    13141 attggatgaa ccttcataac acttcctacg attcgaggat ataagatatt gccatctacc
    13201 tgctgaacaa caagcatata aatcactgca atcagcagtc tatggggatc agtgaatata
    13261 tttgcgatga tcataggaat caaaccaata cttggcccca cataaggaat taaattggct
    13321 acaccagaaa aaatggcaaa aactaaagca tattttaaac caataatact atagccaata
    13381 taagctaaac aacctataat gattgcgtca atcgaaactc cactaatata gcgagcaatc
    13441 gtcgcattta aattctttaa taagcctgca atatgcaagc gatccctctt tagaatcgtt
    13501 ctttcaagca tgggcaagaa tttatgtcca tctaataaga aataaaccaa aaaaactgga
    13561 gtcataatca aaatcaaaac agtactgata agagctgaca agacgctccc cacactattt
    13621 gatacgctat ttaggatatt ttgaagaata tcaacatagg ataagtttaa ctgctgaatt
    13681 gtagcttcta catccaaatt ctggagcgca ggataattag ataagtctat gattaagtct
    13741 tgtactcgac tataaatagt ttgactagat ataatcaaac tagataactg attaatcaaa
    13801 ataggtaaga gatagacaac acctatgacc attccccaga ccaaagtaca caaggtaatt
    13861 aaaataccaa gcaaacgatt gagtttacag actttattta agaaagtaac aatagggttt
    13921 gtcaaataat aaagaaagcc ccctaataaa aatggaatca taattgtatt aagcacgcta
    13981 acaaaagggt taatcaaaga tcccatctgt ctccataggt aaaagatgat ggttaagagt
    14041 aaaatttctg tggtccaaaa aaataattta tttctacgaa acatgagtta cctccctcac
    14101 tttattttac catattttca aaaagcttaa cagatgaatt attaaagcaa gaatattttt
    14161 tttctttatg atagaataag actactatga aaaaaacatt tttaacttta ttaactgtct
    14221 ctcttttagg gggtgcttct actgctgttg ctcaagattt taccattgcc gctaaacatg
    14281 cgattgctgt tgaggcaaat actggtaaaa ttctctatga gaaggatgca acgcaacctg
    14341 tcgaaattgc ttccataaca aaattgatta ctgtttatct ggtctatgaa gctttggaaa
    14401 acggaagtat taccctctcc actcctgtag atatttctga ttatccttat caattgacga
    14461 caaattctga agccagtaat attcctatgg aggcccgtaa ttatactgtc gaagagctgc
    14521 ttgaagcaac tctggtatct agtgccaaca gcgccgctat tgccctagct gagaaaattg
    14581 ctggctcaga aaaagatttc gtcgatatga tgcgggcaaa actcttggaa tggggaattc
    14641 aggatgccac tgttgtcaat acgacaggtc ttaacaatga aactctaggg gataacattt
    14701 acccaggttc taaaaaagat gaggaaaata agcttagtgc ttatgatgtc gctatcgttg
    14761 ctcgcaacct catcaaaaaa tacccacaag tcttagaaat caccaaaaaa ccttcttcta
    14821 cttttgctgg gatgacaatc acttcaacca actacatgtt agaaggtatg cctgcttacc
    14881 gtggtggttt tgatgggcta aaaacaggaa caacagataa ggctggagag tcttttgttg
    14941 gtactactgt cgaaaaaggc atgagagtca tcacagttgt tttaaatgca gatcatcaag
    15001 acaataatcc ttacgctcga tttacagcta catcttccct aatggattat atttcttcta
    15061 catttacact tcgcaaaatc gttcaacaag gcgatgccta tcaagatagc aaagcccctg
    15121 tacaagatgg aaaagaagat acagtaactg cagtggctcc agaggatatc tatctaatag
    15181 aacgtgttgg gaatcaatct tcccaatctg ttcaattcac acctgattcc aaagcaatcc
    15241 cagcaccact tgaagctgga acagtggttg gccatttgac ttatgaagac aaggacttga
    15301 ttggtcaagg ttacatcacc acagagcgcc ctagtttcga aatggtagca gacaagaaaa
    15361 ttgaaaaagc cttcttctta aaagtttggt ggaatcagtt tgtccgcttt gttaacgaga
    15421 aattataaaa aatcgcgatt ttaaaccgcg attttttgat ataagttcat cttcaaaatc
    15481 aaagaacaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtagat
    15541 gaaactgacg aagtcagtaa ccatacatac agtaaggcga tgctgacgtg gtttgaagag
    15601 attttcgaag agtataaaat caaattttat ccaactgatc cctccatttc atagctaatc
    15661 aagcggttca gctcaactgc gtattccatt ggaagttctt ttgtaaaggg ttctacaaat
    15721 cccatgacaa tcatttcagt tgcctcagat tctgacaatc cacggctcat gagataatac
    15781 aattgctctt ctgaaatctt agatactttg gcttcgtgtt ccaaagccac ttgcgagttg
    15841 tgaatttcat taaatggaat agtatctgat gctgacaagt catccatgat aatggtatca
    15901 cattcaatgt gggaaacaga tttcttagag ttcttgttaa aggtgacttg tccacggtag
    15961 tcaacctttc ctccaccttt agcgatggat ttagacacaa tagacgagct ggtatgtgga
    16021 gcattgtgaa tcatcttagc acccgtgtct tggtgttgcc ctgcattagc aaaggcgata
    16081 gagagcatgg taccacgcgc tccttctcca tcaaggtaaa cagatggata tttcatagtc
    16141 gttttggcac ccaagtttcc atcaatccac tcaacagtgg catccttttg agccttagca
    16201 cgctttgtta ccaagttata gacgttatca gaccagtttt ggatagttgt ataacgcata
    16261 taagctccgt ccaaagcaaa aatttctaca atggcagcgt gcaagctatt acttgaatat
    16321 gttggtgctg tacatccttc tacgtagtgg acgcttgctc cctcatcaac gataatcaag
    16381 gtacgttcga actgacctat attttcatta ttgatacgga aataagtttg aagtggaata
    16441 tctaccttga caccttttgg cacgtagata aaagttccac ccgaccatac tgctgagttg
    16501 agggctgcca acttgttatc tgtcggcggt accaacttcg caaagtattg tttaaataag
    16561 tctgggtatt ccttgagtgc ggaatctgta tctgtaaaga taatacctaa tttttggaac
    16621 tcttccttca tgttgtggta aaccacttct gactcgtact gggcagaagc ccctgctaaa
    16681 taagcacgtt cagcttctgg aatcccgata cgttcaaagg tttctttaat cttttcaggt
    16741 acatcatccc aagaacgggc tggtttgtca gatggttttt ggtagtagat taagtcatca
    16801 aagtcaatct ctgacaagtc tgctccccaa gtttgcatgg gcattttttt gaaggtttca
    16861 taagacttca agcggaactc caacatccac tcaggctcac ccttagcagc agataattca
    16921 cgaataacac cttcgttgag tccttttcct gtcgataaga caggctctac atcgtcatgg
    16981 aaaccaaatt tatattcacc aaggtcaatt ggttttggtt ctactctttc ttcagccata
    17041 atatcctttc tttcttcatt tctaataatt cataagacaa aagaaacttg tcttactgtt
    17101 tttcttgatt ttcaattgtt ttcttaagag cattccaagc tagggttgca cacttgattc
    17161 tttgagggaa tttggcaaca cctgacaaga atgccgcatc tccaagttgg tcttgacgct
    17221 catctttttg cccttgaacc atttcagaaa aaatagtcgc cagttctaaa atttcttgtt
    17281 tggtttttcc taaaacggca tctgtcatca tactagcaga agcagttgaa atcgtgcatc
    17341 ctgaatttag aaaagcaata tcttccaaac ggtcctctgc atcaaacttg acagagaggt
    17401 tgatgacatc cccacaagtc ggattgttga gactgatttg ctcagcgtct tctaacttcc
    17461 cttggtgatg tggatttttc gaatggtctg ctaccactgc catataaagg ctatctagtt
    17521 tagaaagtgc cattgaaaaa ctcctttgtc ttttgtaggg catcgactag tttgtcgcaa
    17581 tctgccttgg tattatagat ataaaaactt gcacgagctg ttgctgggac ttccaaatac
    17641 tgaagcaagg gttgcgcaca atggtgacca gcacgaacag ccactccttc ataatccaga
    17701 gccgtcgcaa gatcgtgagg atggagatca cctaggttaa aggcaataac acccgaacgt
    17761 tgagccaaat tctgagaacc gtaaatggtc aatccctcaa ttgcctgcag ttttggatag
    17821 acgtacgcaa tcaattcctg ttcatgagct tcaacggcat ccataccaat cttttccaga
    17881 taatcaactg cagtcgcaag tccaatagct cctgccatat ttggcgttcc agcctcaaat
    17941 ttccaaggca attccttcca actagcagat tgctcgtaga caaaatcaat catctcgccg
    18001 ccaaattcta ctggagacat ttgctcaaga tacttttctt tgccgtaaag gacaccgata
    18061 ccagtcggac cagccatctt gtgacccgaa aaggcgaaaa agtccagatc caagtcctgg
    18121 acatcaatct tcatatgagg tgtagattga gcaccatcca ctaccatgat tgccccaact
    18181 tggtgggcta attgagtgat ttccttgatc ggattgacca caccaagaac attggaggca
    18241 tgagctaggg aaacaaattt aaccttatca gtcaatttag ctcgcaaatc ctccatatcc
    18301 aaggcaccgt ctttaagata gacatagaca agctctgctc cagtctttcg acaagcttcc
    18361 tgccatggaa tgatattaga atggtgttcc attactgaaa tcaagacctg gtctccctca
    18421 gcgagaattt cctcagcaaa gcgtgccacc cagttaaggc tggttgtcgt tcctctggta
    18481 aagagaactt cctttgtaga gcctgcatta ataaacttac gaatggtttc acgagcagct
    18541 tcataagaag ctgtcgctcg ttccgctaag gtatggacac cacggtgaac attggcattg
    18601 tcctgctcat agtaactgtt aatagctttc agaactacta gtggtttttg tgtcgtcgca
    18661 gcattgtcca gatagaccag aggttcatca ttgacaatct gatctaaaat tggaaaatcc
    18721 ttgcgaatcg cttctacatc taacataggc ttccccttag cgttttgaca atttctcttc
    18781 gatagttgca atcatttcat cacgaacttc cttgactgga atctccacga taacagatcc
    18841 aaggaaacca cgaacaacca aacgctctgc agttgcctta tccaatccac gactcatgag
    18901 gtaatacatg tcttctggat caacttgtcc gatagacgct gcgtgtcctg cagtgacatc
    18961 attttcatca atcaaaagaa ttgggttagc atctgaacgc gcttggtctg aaagcatgag
    19021 aacacggctc tcttgttgcg catctgctcc cttagcaccc ttgatgatgt ggccgatacc
    19081 attgaaagtc aaagttgctt tttcaaggat aaccccatgt tgtaggatat ttccgataga
    19141 gttgcagcca tagttagtta cacgagtatc aatcccttgt acctgacgac cacttgaaag
    19201 agctacaacc ttgaggtcag catggctacc attaccaatc aagtcactat caaaatcagc
    19261 aacgacattt ccttcgttca tgacaccgat agcccagtca atacttgcat cgttgcctaa
    19321 tttaccacga cggctaatgt aggcagtgac gttttcacct agacggtcga tagcagcaaa
    19381 cttgacttgc gcaccagaac gtgcaatcac ttccactgtg atattggcag ttactttgtc
    19441 acttccttca ccgcgtgact ctaaacgctc cagataacta atcttagaat ttttaccagc
    19501 gataatcata atatgcttgt taaacggcac attgctatcg ctatcttggt agaaaattcc
    19561 ttcaattggc tctgtgattt ctacgttatc tggaatatag agtacagcac cactgttaaa
    19621 gtaagctgtg tggtaagccg ccaacttgtc atcatcatac ttaacagatg acatgaagaa
    19681 ttcttcgatc agctctggaa tttcttctaa agctgagtga aagtctgtga agacaacacc
    19741 ctgttcagct aactcaactg gagtttgttc gaaaacagtt tgagttccta cttgcaccaa
    19801 cttcaagtga tgatctaaag ctgtgaaatc tggaacattt gctgatggct cattttctgt
    19861 aatcgttcca tcacccagat tccaacggtg gaatttgaca cgctcaataa ctggtaattc
    19921 caaagtctca atcttgtcaa aagctttttg acggagatca gccaaccagc ttggttcagc
    19981 gtgcatttct gaaaaaagtt taatattttc tctagtcatt tacttctcct aaaagatacg
    20041 aggaaattac aattcttcct tgtagtcgta gccaagttct tcagctaatt ttgcgtatcc
    20101 ttcacgttcc aaacgcgcag ccaattctgg accaccagaa aggacaacac gaccttccat
    20161 catcacgtgt accacatcag gtgtgatata gttcaaaaga cgttggtagt gagtgatgat
    20221 catagcacca aaaccttcac cacgcatggc attgacacct ttagacacaa ctttaagagc
    20281 gtcaatatca agacctgagt caatctcgtc caaaagagca aatgttggct ccaacatcaa
    20341 aagttgaaga atttcattgc gttttttctc accaccagag aagccttcgt tgaggtaacg
    20401 ctctgccatt tcttctttca tgttgagcaa ttccattttt tcatctagct tagtaataaa
    20461 ctcacgaact gaaatcttct catcatcttc tttacccgca ttcatagcgg cacgaagaaa
    20521 ctcagcattg gtaattccag ggatttctga tgggtattgc atagcaagga aaagtcccat
    20581 acgcgcacgc tcatccactt ccaactcaag gatgtttacg ccatcaaaca aaacttcacc
    20641 tttagttact tcatagtttg gatttcccat gatagcggca gaaagagtcg atttacctgt
    20701 accatttggt cccatgatag cggcaatttc tcctgttttc agggtcaggt taaccccttt
    20761 taaaatttct tttccttcaa tctcaacgtg aagatctttg atctctaata ctgacatgat
    20821 agttcctttc tttttcaaaa cttttacagt acttactaga aaaacgtctg atttccccag
    20881 aaatagagca aaaattctat aaatatactt ttctagtata acaaaaaaaa gcctaaaagg
    20941 ctttgatttt gtctggaagc tgagggctag tctttcctat taaaatgctg atcgatgaca
    21001 tcaacgattt tgcccatcac ataactgact cggaaatttc taaagagtaa aattgcccaa
    21061 aaggctgcca taatatagcg gccagtcatc caggcttcat tgaaaaaata ggtctcagca
    21121 gctgtaaaca gcgccataat aataaattgt tgtttattca taaacttatt gtatcatgaa
    21181 atctttcttt agtcttcctc taccttcact ttatcagcca aaaattcaaa tccttctgga
    21241 atcaggcttt cttctacttc cttttcagtt tgagaagatt tggctttggc tgaaaaggct
    21301 gcgcgaactt ctttccattc ctccatggaa atagctaaaa tctcaggtga aaaacctgcc
    21361 gcctgactga ggatattacc aaacatggta ttgagattgt ctcgtttcat agtttgacca
    21421 gcattgaagt tagactcaaa agcaagaata gcatggtgtt cattggcagc aaccggttga
    21481 gaaccaacta gcagagcctt gtccggccca cctagacttt caattacctc tccccaggca
    21541 ttctgcaaac gaattagatt ttgacgtgct aaatcaggat tttcgacggc ctcttgtaag
    21601 atagattgca ctttattgcg atcgacacga tagactgttt tgcccgtagc tggtcgacta
    21661 ggagctggtg caacttgttt aggaaccgca cctacattag aaagctcttg tttgagacgg
    21721 gcaacttcct gtctcagcgt agcaatttca ttttcaaccg ctcctgatag agctggttcg
    21781 ggcttgattt ccgccaaacg gacggtcatc atttcagcat aaatcttggg ctgcaaacta
    21841 gacttaatat ctgctaaact cactgttgct aagcgaatca tttcaaacag atttttttga
    21901 ggaagtgcca aattttctac aaagactgaa ctatgatgag tattttctcc ccctgtttga
    21961 acaattaaca agtctcttaa atagtgcaaa agatcggtca caaaacgagt catgctctta
    22021 ccattgtcaa aaagaagatt caagcaagac aaagctttgg gaacatcctg ttgagacaag
    22081 gccgccacat aatcatccaa ggctgatagg ctaatggtgc cagtaatttc ttcagagata
    22141 gcagtcgtca gctcatttcc ctgtgtcaaa ctcagggctt gatccaaaat agacaaggcg
    22201 tcccgcattc caccttccgc ccgtctggca atgatttcca cagcctctgg ttcagaactg
    22261 atattttctt tttctaagat atagtgaata tgttccttaa tatcctgtgt cttaattgat
    22321 ttaaactcaa aacgttgcac acgggataga atagtagcag gaatcttgtg caattcagta
    22381 gtggccaaaa taaagactac attctgtgtt ggttcttcca gcgtctttag gagggcatta
    22441 aaagcccctg tagacagcat gtgaacctca tctatgatat aaaccttata acgagcaagg
    22501 ctaggcgcat aggtagattt atcacgaatt tcgcgaattt catctacccc attattagaa
    22561 gctgcatcca tttcaatgac atcttctaaa ctaccgtccg tcactgcttg acaaatatag
    22621 cagttattgc aaggttcgcc acccacttga ttgggacagt tcatagcctt ggcaaagatt
    22681 ttagcaacac tggtttttcc cgttccacga ggaccagaaa aaagataagc gtgacttatt
    22741 ttctcttgct ccaccgcttg tttaagagtc ttagccacaa cttcttgacc aactaactgg
    22801 gagaagtttt gacttctata ttttcgataa agtgcttgat acattaagat ttttcctcaa
    22861 acatcgtaaa gtcccatgtt gtcttttcaa gcaaaatagc gacaaattgt tccaaataat
    22921 ctcgatccat agcatcgtaa tcctcaatct ctgaagaatc cagatccaga actccaagta
    22981 actgaccatt cttcatcatc ggcaccacaa tttcactttt agctagacta tcacaagaaa
    23041 tatagttgag ataggtcgtc acatctccaa caataacagt ttcctgaaag tgagctgcct
    23101 caccacaaac acccttgcct agtgcaatac ggatgcagga aacacctcct tggaaggggc
    23161 ctaaaaccaa ttcctttcca tcgaacaaat aaaagcctgc aaatacggta ttaggaaaac
    23221 gtgattttat gagagcactg gcgttggaaa gattagccaa aacattggtt tcgccttcca
    23281 ataggaagga caattcttca tttaacattt gataacgtga ttgtttttct gattttaaca
    23341 tagaactatt atatcaaaaa aggagcagag acaaaagaaa aatcccttgt ttagtaaaca
    23401 aaggattttg ggctctataa tatttgtagt gggtaaatcc cctatggata ttatggagcc
    23461 tattttgtgt agaaaaaaag tcccatatga cctataatga aaagcgacca aacaactcat
    23521 tagaaaga
//
LOCUS       DAVHSL010000031        23377 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000031 DAVHSL010000000
VERSION     DAVHSL010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.031"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1310)
                     /locus_tag="VVR39_001299"
     CDS             complement(<1..1310)
                     /locus_tag="VVR39_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEU6030787.1"
                     /translation="MKSGKHWLRASTSLFGLFKVLRGGVDTTQVMTETVEDKVSHSIT
                     GLDILKGIVAAGAVISGTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSN
                     SASSTSLSASESASTSASESASTSASTSASTSASESASTSASTSISASSTVVGTQTAA
                     ATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGN
                     TTVNGAPAINASLNIAKSERKVYTGTGLDSVYNVPIYYQLTVTNDGLKLTFTYTVTYV
                     DPKTKTLGNISKKMSNGYSIYNTGTSIQTMLTLGSGLGKPSGVKNSITDKNGVLVQFY
                     NISTMTKQGSGYTWANGAQMNGWQAKKGYGLTSSWTVSIIGTDTSFTFTPYAAKTDNI
                     RINYFNGKGKVVESSTTSQSLSQSKSLSVSASQSASASASTSASA"
     gene            complement(1615..2076)
                     /locus_tag="VVR39_001300"
     CDS             complement(1615..2076)
                     /locus_tag="VVR39_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6030788.1"
                     /translation="MRKERREQGNLERKKRVVKKRKILLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2073..2183)
                     /locus_tag="VVR39_001301"
                     /pseudo
     CDS             complement(2073..2183)
                     /locus_tag="VVR39_001301"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2453..2833
                     /locus_tag="VVR39_001302"
     CDS             2453..2833
                     /locus_tag="VVR39_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6030789.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEASLDFLI"
     gene            2932..3153
                     /locus_tag="VVR39_001303"
     CDS             2932..3153
                     /locus_tag="VVR39_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6030790.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3170..3484
                     /gene="trxA"
                     /locus_tag="VVR39_001304"
     CDS             3170..3484
                     /gene="trxA"
                     /locus_tag="VVR39_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6030791.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            3789..4322
                     /gene="queF"
                     /locus_tag="VVR39_001305"
     CDS             3789..4322
                     /gene="queF"
                     /locus_tag="VVR39_001305"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU6030792.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(4576..5244)
                     /locus_tag="VVR39_001306"
     CDS             complement(4576..5244)
                     /locus_tag="VVR39_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU6030793.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5355..6146)
                     /locus_tag="VVR39_001307"
     CDS             complement(5355..6146)
                     /locus_tag="VVR39_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU6030794.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDGGLDKEIDKIGLPTLERSFRALIYATLLSDDANQ
                     QSIFYQRLKAEIRNVLLNQGLHYLSKEEDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(6393..8189)
                     /gene="pepF"
                     /locus_tag="VVR39_001308"
     CDS             complement(6393..8189)
                     /gene="pepF"
                     /locus_tag="VVR39_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6030795.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKTLTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(8200..8943)
                     /locus_tag="VVR39_001309"
     CDS             complement(8200..8943)
                     /locus_tag="VVR39_001309"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU6030796.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLLELEK"
     gene            complement(8945..9895)
                     /locus_tag="VVR39_001310"
     CDS             complement(8945..9895)
                     /locus_tag="VVR39_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU6030797.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(10033..10461)
                     /locus_tag="VVR39_001311"
     CDS             complement(10033..10461)
                     /locus_tag="VVR39_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6030798.1"
                     /translation="MEIEISGFTGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFFSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10463..11530)
                     /locus_tag="VVR39_001312"
     CDS             complement(10463..11530)
                     /locus_tag="VVR39_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU6030799.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVRKDVVQTHKAMKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            complement(11549..12019)
                     /locus_tag="VVR39_001313"
     CDS             complement(11549..12019)
                     /locus_tag="VVR39_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU6030800.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKEGLEEGEFYPYPRY"
     gene            complement(12310..12762)
                     /locus_tag="VVR39_001314"
     CDS             complement(12310..12762)
                     /locus_tag="VVR39_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU6030801.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(12799..12978)
                     /locus_tag="VVR39_001315"
     CDS             complement(12799..12978)
                     /locus_tag="VVR39_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU6030802.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            complement(13115..13294)
                     /locus_tag="VVR39_001316"
     CDS             complement(13115..13294)
                     /locus_tag="VVR39_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030803.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13459..13698)
                     /locus_tag="VVR39_001317"
     CDS             complement(13459..13698)
                     /locus_tag="VVR39_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030804.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            13968..15239
                     /locus_tag="VVR39_001318"
     CDS             13968..15239
                     /locus_tag="VVR39_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU6030805.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDKGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            15504..15576
                     /locus_tag="VVR39_001319"
     tRNA            15504..15576
                     /locus_tag="VVR39_001319"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15537..15539,aa:Lys,seq:ctt)
     gene            complement(15786..17105)
                     /locus_tag="VVR39_001320"
     CDS             complement(15786..17105)
                     /locus_tag="VVR39_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6030806.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17115..17960)
                     /locus_tag="VVR39_001321"
     CDS             complement(17115..17960)
                     /locus_tag="VVR39_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6030807.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRFAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            complement(17962..18864)
                     /locus_tag="VVR39_001322"
     CDS             complement(17962..18864)
                     /locus_tag="VVR39_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6030808.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYTFTDYYLLTPDERKFVGFENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            complement(18960..20270)
                     /locus_tag="VVR39_001323"
     CDS             complement(18960..20270)
                     /locus_tag="VVR39_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6030809.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(20397..21392)
                     /locus_tag="VVR39_001324"
     CDS             complement(20397..21392)
                     /locus_tag="VVR39_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6030810.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            complement(21754..23235)
                     /locus_tag="VVR39_001325"
     CDS             complement(21754..23235)
                     /locus_tag="VVR39_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6030811.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT         7175 a         5028 c         3997 g         7177 t
ORIGIN      
        1 gctgaggcgc tggttgacgc tgaggctgag gcgctttgac tagcacttac tgatagtgac
       61 ttagactgtg aaagtgactg actggtcgtg ctagattcaa ctacctttcc tttaccattg
      121 aagtagttaa ttctaatgtt atctgtttta gcagcataag gggtaaatgt aaaggatgta
      181 tccgttccaa taattgatac agtccaagat gatgttaatc catatccttt cttagcctgc
      241 caaccattca tttgggcacc atttgcccaa gtatacccac taccctgctt cgtcattgta
      301 gatatattat agaattgaac cagtacacca tttttgtcag taatggagtt ctttacacct
      361 gaaggtttac caagaccact gccaagggtt aacattgttt gtattgaagt tcctgtatta
      421 tagatagaat atccattact catctttttt gatatattac caagagtctt tgttttagga
      481 tccacatacg taaccgtata ggtaaaggtc agttttaagc catcatttgt cactgtcaat
      541 tgatagtaaa ttggaacatt atataccgaa tctaaacctg tacctgtata aacttttctc
      601 tcacttttag caatgtttag acttgcatta attgcagggg cgccatttac agtcgtattg
      661 ccagaaaaaa cagcagcttt tatagaagcc agcaattgct cgatggaatc cactgaacgc
      721 ttgcgtcgct tagcataaga ttggagattg acatttgtaa ctgatgctac ataatcacta
      781 gctggtttct tacgatcttc ttcgaccttc ttagcagttg cttctgtagc ggcagctgtt
      841 tgtgttccta ccacagtaga tgatgcagag atacttgtcg aagccgatgt acttgctgat
      901 tctgatgcac ttgtactcgc tgaggtcgaa gcgctggttg aggctgactc agatgcagat
      961 gtacttgccg actctgaagc tgacaaacta gttgaactcg ctgaattact tgtagatatc
     1021 gtacctagaa ctactgtacc atttgttgcc aaagcatccg ttttctctac agttttttca
     1081 agtactgctg actcatttgt aaataccttc gtttgagttg caacggttcc actgatgaca
     1141 gctcccgcag caactatccc cttgaggata tcaagcccag taattgaatg acttacttta
     1201 tcttctaccg tttcggtcat gacctgagta gtatcaacac cacctcgcaa gaccttaaac
     1261 aagccaaaaa gagaagtcga ggcccgtagc caatgcttcc ctgatttgat taatttgaac
     1321 cgagttactc ggtctgtttc tctatattca ctcttctgac gtctaaaaaa tattttgaaa
     1381 tttcctttcg agtattattt tcatgtatgg atataaataa attaccatac tataattata
     1441 gaatagggaa cccaaaatag caagaaactt gaggtatttt tgctaaaaaa aaaaagcatt
     1501 ttactatttt gtatatatat atattataag ataagttttt tataaagaca cgtaactgag
     1561 tataaatcag ctaatttttg gtttacatcc ctatttttat gcataattat tctgtcattc
     1621 tctaatttgt gaatcaatat atctgattag aaaactacca ttgagttttt gctccacctc
     1681 attagtccgc tcaaaacgcc gtccgctaat cttgtcatag actttctccc ctctaggagc
     1741 ccctgcataa ggacgataga ggtagcggtt gattcccgtt tcgtcaatat ataggactgg
     1801 taaatctttt aggttatcca aaatatcaag aaactcagaa actttctcag gcttttgttc
     1861 cctaaaactg gtcgtctttt ttaaaatgac cttaatctgc tttaaaactg cccatacgga
     1921 gggcaaagca caatcaaaac gggccgcaat ttcccgtaaa aaagcgtctg gatgagcctc
     1981 tacaaaggct ttcaattctt ctaaaaggat cttacgcttt ttgacgactc gctttttccg
     2041 ctctaagttc ccttgttcac gtctttcttt tctcacgtga agagagttct gacgccaaca
     2101 ccaaaaacct tggccgcctc gacatgtctg tgccctcctt tgatggaatc taatgatcct
     2161 tgtttaaaat cagtactata tgcatagctt tattagacca tgcttatttt aaactaagca
     2221 actatagata gagaaatgaa ataaaatctg aattcgaatg cgataaggag ttagaaattg
     2281 aaacaatagg atttccccat tattcacaca aaaataaaac cactaaaaaa cagagcttgc
     2341 cagtattctt gaaaagtagt ataattattg catgcgcaat catcttgtga cgcagagact
     2401 gcccgttaat ggactttctt ctatttatga ctctaaaaag aaaggagaca ctatgaccta
     2461 tttggaaaaa tggtttgact tcaatcggcg tcagaaagaa attgaaagtc tcttggaaga
     2521 gaccattgcc caacagagcg agcaaagtct gaccttgaaa gagttctacc tgctctacta
     2581 tctggacttg gctgaagaaa aatctctacg ccagattgac ctgccagata agcttcatct
     2641 gagcccgagc gcagtttcta ggatggtggc tcgcttggaa gctaaaaatt gcggtctact
     2701 cagtcgcatg tgttgccatc aagatagacg ctctagtttt atctgcctga caaatgatgg
     2761 gcaaaagaca ctggcctcgc tacaaaagac tgtcgaagaa agcttggaag caagtttgga
     2821 tttcttgatt taagatgatt ttaaaaaaag ttgcgtgcgc aatcattttt cttgacattc
     2881 tcttttataa ggagtaaaat aaagttagca ttaaacaaag gagttttaaa tatgattgaa
     2941 attacctata tagatgccag caagaacgaa agaactgtga ctttcgagtc ttatgaagac
     3001 tttgaacgtt cgcaacaagc ttgccttatc ggcgtcgcag actactaccc tgtccaaaaa
     3061 ttaacttaca agggtcataa tttggactac catgggactt atggagatat cttcttctat
     3121 ctcatgaaac aagatttaag ccaatataac taaaaaaagg agaaatacaa tggcaaaagc
     3181 aattacagat gcaacattcg aacaagaaac aaaagacggt ttggtcttag tagacttctg
     3241 ggcaacttgg tgtggtccat gtcgtatgca aggtccaatc ttggacaaat tgtctgaaga
     3301 actttcagaa gatgtcttga aaatcgttaa aatggacgtt gatgaaaatc caaacacagc
     3361 tcgtgctttt ggaatcatgt ctattccaac tcttctcttc aaaaaagacg gccaagttgt
     3421 caaacaagtt gcaggtgttc acacagcaga acaaatcaag gccatcattg ctgaattgag
     3481 ctaatcaaac gagagaccaa gtactttctt tggtctcttt tttcttgctc tttgccattt
     3541 ttcaaaaaat atgctagact atagtagatt gaaactagaa tagtacacct ctacttctaa
     3601 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt
     3661 actatataag tagaatatta cgatgtttgg gatatgccat cgctaaaaaa actcgatttg
     3721 gtatttttta gctccctaat gggagctttt tgcgtgctct gaacatttcc cattttggaa
     3781 ggagtactat gaaacgtcaa tcagccttgg tcgtctttag tggtggtcaa gattcaacaa
     3841 cctgcctttt ctgggccatg caacactatg aaacagtcga agctgtcacc tttgcctacg
     3901 gccaacgtca tcacctcgaa attcaaatta ctagagaaat cgctaaggaa cagggcattc
     3961 gtcaccatat cctcgatatg tctctgctgg gacaaatcac tgctcagcca gactttgcga
     4021 cgattcatat ttcctacatt cctgacaagc tctgtgtcga gtcaaaatcc ctcaaactat
     4081 atctatttag ctaccgaaat cacggagatt tccacgaaaa ctgtatcaac accatcggga
     4141 aagacttggt caacttgcta gaccctcgct atttagaagt ctggggaaaa ttcactccgc
     4201 gcggtggcat ttcaatcgac ccctactata actacggtaa gcaaggaact aagtatgagg
     4261 gcttggcaga acaacgcctc ttccaacacg acctttatcc agagaaaatt gacaaccgct
     4321 aaagtcatac tcaatgaaaa tcaaagagca aactaggaag ttagccgcag gttactcaaa
     4381 gcagtgtttg aggtggcaga tagaactgac gaagtcagct taaaacactg ttttgaggtt
     4441 gcagatagaa ctaacgaagt cagtaaccat acctaggaca aggtgaagct gacgtggttt
     4501 gaagagattt tcgaagagta tcatacgaaa aagccctgtt cctcaagatg aggagcaagg
     4561 ctttttgagt ttcaattatt cttctgttcc aaggaaattt tttgcaacaa gggctgcaag
     4621 aactccacca gcgattggtg caaggatgaa aatccaaact tgttgaaggg ctgcgccgcc
     4681 taccaagaca gctggtgcca agctacgagc tgggtttact gaaagtccag taatcttcaa
     4741 tccgacaaga atcatcgcca tcaatgacaa accgattacc aaaccagcaa tcgcgccatt
     4801 gcccttactt tctgaagtca cagtcatgat aactaagaca aacaagaaag ttgcgatgac
     4861 ttcaaacaag aaaccaccaa agacagtgac tccgtttgcc aaggcatttt caccaagact
     4921 agcagttgac atacctgaat tacccaagag gaagaagact gcgccagaag cgatgaaagc
     4981 tccaacaacc tgaccaagga tgtagtttac aagttctgaa gatgacaaac gtttgtttac
     5041 aaacatagca atcgaaacag ccggattcaa gtgagcacct gaaacagttc cgattgagta
     5101 ggctgccacc acgattgcca aaccaaaggc aaaggcgatt ccaaggtgac caaggccatc
     5161 aagaccattt ccaaaaacaa cagctcctgt cccgacgaat acaagcatga acgtaccgat
     5221 taactcagca acaaattttt tcattttctt tctccttttt tcaaaaacta gatactagtc
     5281 tatcaaaagt aggaaagggt ttcaagaaaa ttgattggaa attttttgaa aatcatagaa
     5341 ctattaactt atccctagta ttgaaaagac tggatagctt ctttcaggtc atcttgtaaa
     5401 ctatttctct ggtcaagttg gacatagact tccaacagac aggttctgaa gttggaaaat
     5461 ttgtaaaaat cctccctttc ttctatcgga aaatcaacag tttttatcca agaagctact
     5521 tgttcttgcg ctaacttccc ttgtaaaata ggttcataga tcactcttgc taaacgccaa
     5581 tcctcatcat ctgtaaagcg aatcgacatt cttttaaata gttggccaag tatatcaaat
     5641 acttcatgaa ctctgttttt aggaaagtct ggatgacaaa ccacctctgt cagtaaatcg
     5701 gctccatgtg caaaagaatg aacccaacca tactgacttg agaaacctgt tgtatcctct
     5761 tcttttgaaa gatagtgcaa gccttgattt aaaaggacat tacgaatttc tgcttttagt
     5821 ctctgataga aaatcgattg ctggttggca tcgtcagaca agagagttgc ataaataagc
     5881 gccctaaaag aacgttcaag tgttggcagg cctatcttat caatctcttt atctaaccct
     5941 ccatcagatg aaaccccttc agcaatgaaa tgaaattgct cctgtgtaaa tagctcttcc
     6001 tgaatccctc tagcaaagct tgtaaaaaca aggtcatcgc gaatttctgg agaaggatct
     6061 cccaaatgat caagcaacca ctggatttcc tcctggttat aatttggttt ttcttctgct
     6121 atttttctta gtaaatcttg atacatggtc aatacctcta catttctagc aactgttcaa
     6181 aaaggcagtc ttaaatgact caatattgaa ttctcaatta aatacaatct gatataaaat
     6241 gacgtaaata actatcaata ccagttctac agtaagttca aatttaacat cacgaccttc
     6301 aacgacattt ttgaaaatag ctacaactaa gacaaataga atgacgctta acaagcccat
     6361 aaacatcatt ctaaaaaatt tttctattcc ccttactccc ccaactcagc actgtaggcg
     6421 ataatctggt caactgtgtc agacaagaat tggatggtat cacggagtgg tttgtctgtt
     6481 gaaatatcag caccgataat catggctgac tcaagtggtg tcttgctacc acctgatttg
     6541 aggagattga gccagtcttc agctccagtt tctgaatttt taagatgaag gtaaccagca
     6601 gtcgagataa ctagtcctgc tgagtaagtg taactataca agcccatata gtagtgagct
     6661 tggcgcatcc aagtcaaagc tgcatcgtcg tcgatttcaa tggcatcgcc ccaaaaatct
     6721 gtcaaaactt ccttcataat actgttgagt ttgcttgctc cgaaggtttc tccttcttca
     6781 atcaatgtat acaccttacg ctggaaggcg gcttccaaga ggtgggtgat gaaattatgg
     6841 aagtaggtgt ctgtcaagcg atgagccaga gcgaagcgtt tttgacgtgg gtcattagac
     6901 tggttctcta agtaatcact gagtagcaat tcattgaagg ttgacggtgc ttcaacataa
     6961 taggtcgaca tgtgggcgtt gaaatagctt tgatgattgt ctgaaaagat gaattgacca
     7021 gaatgcccga tttcatgaat caaggtatag acatcgctca aacggcctgt ccagctcatg
     7081 agtacataag ggtgtacgcg atatgggtcc gccgcataac caccggaatc cttgccactg
     7141 ttagcagcaa agtccaccca gcgctcttct tggtaacgag caacttcctg acaatattct
     7201 tgccccaaag gttctaccga cttcatgacc aaatcatagg catcgtcaat agtcacttca
     7261 ggattcaggg cgctgtccaa gtccaatttc cagtctgcaa aggtcatctt ttcaagacca
     7321 tttaccttgg caacatgctt gaggtatctc tgagcgactg gtgcaaagtc cttcatgatg
     7381 aggtcaatct ggcggtcaaa catgacacgg tccacttctt gttcagctag aagatagtca
     7441 aagacagagt cgtatccctt catatcagcc aagagttttt cagacttgac ctgagccaga
     7501 taggctgctg cagccgtatt ttggtgctta cgaagtccct ctgagaagga acggaaggat
     7561 ttctcacgaa cctcagcatc ctcatggttt tggtagaaat tctcataggt cacaaagctg
     7621 tttttatagg tcttgccatg ggcttcaaag tcagccattt caaaatcccc agctcgcatc
     7681 ttagtataaa tgtcctgcgg actatagaaa acttcaccga gattggtcaa ggtcttctcc
     7741 acatctgccc ctaagtagtg ggcttttttg attttagcct gacgaatggc agctgttaaa
     7801 tgtggcaatt tacccaaacg gtccaagact tcctcgtctg ctgccaccaa ggcatcgtca
     7861 aagaaggtca aggctacgct ggcatctgtt tcaaattcca tcccagcttg agcaatattt
     7921 gcaaattcgt cattgctata gtccgtcgtc tgaggcataa aaccatagtt gccaatatgg
     7981 ctcatctgaa tgtagatctg ttccaattcc gcaaaggcct tctcgaaatc ctcaaaagtg
     8041 tgaagattgc ccttgtaatc acggctaaac tggttgatgt cttcgcgagc tttctcgatt
     8101 gcacgcaaga aatcctcacg gtcttggtat agagctgtta aatcccaaag ttccttctct
     8161 ggaaattctg aacggtgttt ttgttccatt ttcttcctct tatttctcta attctaataa
     8221 aacactaagg gctgataaag cgtaaagcgg tgctgtttct gctcttagaa tgcgagggcc
     8281 aagtcctgcc aaaacagctc ccttagcttc aaaattttca atttccgcag gtgacagacc
     8341 accttctgga ccaaagataa agagcaattt ggctcctttc tcgagtccag taactgcttt
     8401 tataagagca gcggcttctc cttctttggc cgcctcttca taggctacta agatgcggtc
     8461 aaactggtca agttgggcta gaaagtctgc tttattctcg aaaagatgga tacttggaac
     8521 aatattacgc ttgctttgct cggctgctcc aagggcaatt ttttctagtt tttcaacttt
     8581 tttacccaat ttcttgccat cccacttggc aactgaccag tctgcaggaa aggcccagat
     8641 ttggctagca cccagttcgg ttactttttg agcgatgaac tccagcttgt ctcccttggg
     8701 aaatccagat gcgatggtca cttggactgg tagttccaca ttgtcattta attcttggac
     8761 caactcaaac tgacgatttt ccatatccag cacgcgcgcc aagcgcttga tgccatcatc
     8821 aaagactaag gtaacctcat cctcttcttt caagcgcata acctgaaaca tatgcttact
     8881 ggtttccttg tcctcgatag tgacaggaga gatagcactg ccttttacaa aatactgctg
     8941 catgctagcc tccaatcaca ccagagatat ccttggtttt cttaaagaca caggtattcc
     9001 attccccttg aaccatgtga gtttcgagga aaaatccagc tgattcagcc aactcgcgca
     9061 ccatgtccca cttatccttg ataatgccac tcatgatcag gtaaccttca tccttaacca
     9121 agcgataagc atcctctgtc agatgaatga ggatatccgc caagatgttt gccacgatga
     9181 catctgcttc aatctccacg cctttaagca aatcgcctgc cgctacatgg atattttcca
     9241 ttccagggtt gagctcaata ttttcctgag ccacacgaac tgccacatca tccaggtcat
     9301 aggcgaaaat ttctttagcc cccagaagcg agctggcaat agagagaacc cctgaaccag
     9361 ttcccacatc tagcaccgtt tcgccaccac gaagaacctg ttccaaggca aagaggctca
     9421 tcttggtagt tgggtgggtt cccgtaccaa aagccatgcc aggatccagc ttgataattt
     9481 tttctcccgc agtcgcctca tagtctgtcc aagagggaac gatggtcaaa tcatgagtga
     9541 tacgagctgg ctcatagtat ttcttccagt tatctgccca gtcttcctca gccaaggcag
     9601 tcgtacctat ttttaactct cccaaatcca taaaatccgt caattctgat atgcgagcct
     9661 gcaagtccgc ctcaaccact gtcacatcca ccgtgtcagg gtagtaggct gtcactacga
     9721 tttcttcttg ctgctccacc tctgggaaaa tctcgccaaa acgatccaca tttcccatat
     9781 agtccatgct gtcttcaatc gcgactcctt gcgctcccag ctcaatcaag agattggaaa
     9841 ccaactcctc tccctcacgc ttcactgtaa cttttaactc ttgccatgtt tccattatta
     9901 agataccaag cccgtaaaat acaaaaccaa aataggaaat tctctgaaga cgcttgtgtc
     9961 taagagaagt ttatcttttt ggcacagtgt ttagggcggg ttcagtttag aaatttaact
    10021 gaaccatcct ttctaatcac ttacttttaa ataatctttt aatctctctt gcaactgagg
    10081 gacaacttga ctggaactaa aaaattcctc aacattcatc agctgatagc cctgtccttc
    10141 atctccaaat acgatactgt caaactggtt ctgtgtcaac tgaccaacta gaaatacaga
    10201 ttgtttatcc gcaaaaagca tacttggata aaccttactc caaagcagac aatcttcagt
    10261 cagatgaatg cccagttctt cataaacttc acgcgccgcg cactcaaaag gactttcatc
    10321 accttcacgt ccaccacctg gcaactccca catgttggga caagggatat cgtccttgtc
    10381 atcacgcaaa atcgtcagta gcttatcccc acaaaagagg gcaatcttgc aacctgtgaa
    10441 accagaaatc tctatttcca tattagactc cttcggctaa ttccttttcc agctctgcta
    10501 acaagttttc ataatagcgt ttctcgtccc tcaacattcg actactatcc attttctgtc
    10561 tagcaatctt catagccttg tgagtttgaa ccacatcttt ccttacctta aattgatacc
    10621 aagcttgtat cacttgaaga ttggacagtt tgagagacag aaacgatttg acctgtcgaa
    10681 tactagcata ttgctccgct tgctcaaaat ctccttccaa caaggcgata tgaagtaggg
    10741 atagttgggc aactgtctgc atcatcggag tagttgtcct ctcaagtaat gcttgaaact
    10801 gctgtttagc tacttcttcc ttcccttcca aaatggaaac ttcaccttgc atacctaata
    10861 caccatccgc aaaactccct cgtgcatcct caggaactgc ttgaacaaag tctttcaaat
    10921 catattcttg aggagccagc aaagtttgag cagaatgtct caataccagg taggcgtatt
    10981 tggtattttc agggtgttgt agtaattccc aaatttttgc tccatcggtg atgtcgactg
    11041 gcaaaatgtt atttaggaag aaagataaat taagaaaaat ccaagtccct gcaaaatacc
    11101 agcttcttgt caaaaatcca aacactatcg ccaataatat caagccgaga tgaaccatca
    11161 agcctcctga aagcatcagg atgattcttt gatcgctttc atcctctttt aaaccaatgt
    11221 attgagcacc aacatttttc agaatggctg ttctactaag atgaaacctg cctgactttt
    11281 tggtcaaaat aaaatgtcct aatccaaaag ccaccagccg atagcctgtc aagtagccac
    11341 aaaaagcatg acccagctca tgaagaataa agattaaata catgcttaga agagcgaagg
    11401 cataaccaaa agtaaaggct aaaactgcgg aataccccaa ctctgcaaat gcgattgttc
    11461 cacaagcaaa agctagcata ataaagacaa cagctagcac ataaaccaaa taagtcccaa
    11521 ttttcttcat aacaccgcca accaactcct agtatcttgg ataagggtaa aattctccct
    11581 cttccaagcc ctcttttcct tcttcaaaga cttcttggtt ccattccatg ataaattcct
    11641 ctgcttctgg gtcttccaaa aagtccatga ggacatctag cccaacctca gcagtatctt
    11701 taaggaaaag cgcaaaataa gctaaaaatt cacgggaaaa tcctttttta ggcaggtaag
    11761 gaataacagt caaatagtct tcctcattga ctgttgactt ggcaggattg tagaaaagga
    11821 ccgcttcctc aaaaagaatg tcatctgatg aaacctctcc gtcttcatcc accatctcca
    11881 cacctgcagc attttgcgct tccaatagaa aactcacttc taccgcatgg ttgcgtttgt
    11941 cccagctaat ctcaaagtca aagggaaagt tcttgtccaa ctcttcctct aaaacatcta
    12001 aaaatccgta tgttgccatt ttgtcctctt tctatgcgac tctttaatcg ccccgattgc
    12061 tcggaaatat gctaaaatag atactaccat cttaccacaa aattatttta tgtcctaatt
    12121 ataccatatt acctcattta aacccttggt atcagtgatt ttcttaaaag tctgatttct
    12181 tcatttctca taaaaatcaa tataaaaagc cctcgaaagg gctaataaat ctataaaatc
    12241 aataggcgag taactagcac aagtggacgt gcttttttat tgactattac cacgatacca
    12301 cgcttaatct taggcttgaa ctttcttatc tgcaatagcg tctgtcaaag tctgagaaaa
    12361 gttaagtccc atttctcgtc ccaacttatc tgcccatttt ggtatggtca aagtcttttt
    12421 aatgggttcc tgacttccta ggtattctga tacatcaaca gataccatag aaataaaaga
    12481 tttatcaagg tcataggttg acacgaaatc ttcatcatct ttaaaaggat cattatcaat
    12541 taaagacaag ctattgatat ctgatggctg aggtaactct ccatcactct ctatcaaatc
    12601 tgcaacagtt atccctagcc actccgaccc catagccaaa gcctcagaaa tcccctctcc
    12661 ttgtgtagct gagtattcaa aatctgggaa atggacaaaa taagtcgctt ctgttccgtc
    12721 tgtgtcatca taataaaata aagctggata cgtaactaac atttcactac ctccatatca
    12781 aaaagcaggg gctgaatttt acaacccagc ttgctttctt atccctcttt cagtgtactt
    12841 attcagctca ccatgaagga ttgtgatagg tctttcccct tgcttctcga ttttaatatg
    12901 ggagccttta ccgcctctag tctttatcca accatgggcc gtaaggagtt taaccatctc
    12961 tttttgtgtc ataggtatag cgcttttacc tcctgacaac accattataa cacgtgttac
    13021 acgtattgta aaggagtgat acttattatt ctattataca taaaagcccc tagatgtggt
    13081 tctaagggaa accaatttat tcagacctat ttttctaatg agtagtaaaa actgcttctt
    13141 tatcgagcaa ttcatcatct gtatagtcaa ttgtaaaagt atctcgatct aagacagatt
    13201 gaggcggagt tgaatgaatc ataggaacac tgcgtactct atatttttta tctccaattt
    13261 ttacaaactg atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc cttaccgtac
    13321 tcaagtacag cctgcggcta gtttcctagt ttgctctttg attttcattg agtatgatta
    13381 actctcaagt cttcgaaatc aggattttca acagttatta caaggaggcg atttactact
    13441 tcaaaaacat caattattct atttttcata ttttttcaac ccattattag aatgaacttc
    13501 ttggtaagca aaatcaagtt tagatttaat gttttcgtac aaatctaaaa tctcttttgg
    13561 agtatcttcc cggaagaaaa gttttctttt ccctgaaata acttgatcac taagaatcca
    13621 atgacgaatt tgttttgtaa aaatcaaaat ttcctgactt ggtccatcat ttccattgct
    13681 tatcacctct cttttcatta tagttcatac aatgacattt agcaatatta tttctcaagt
    13741 cagcacttcc acttctttag gctcaactat cctattttga gctttaagga aaatcaaatc
    13801 tctcatgctg atacctctcc tcattaaatt aaatagtaaa aaagattcta tctcactccc
    13861 tgattattac aaaaccattg aaatatcaca actaataggc tagaatggac atagtaagat
    13921 atagtagatg agtcattcta ctcaaatcca cgttagaaag gactgctatg ccagacaatc
    13981 tcgcgcttcg catgcgccct aaaaccatcg accaggtcat cggtcaggag catctggtcg
    14041 gacctggaaa aatcatccgc cgcatggtgg aagccaaccg cctgtcctcc atgattctat
    14101 atggccctcc gggaatcggc aaaaccagta ttgcctctgc catcgctgga acgaccaagt
    14161 atgcctttcg aactttcaat gcgacagttg atagtaaaaa gcgactgcaa gaaatctcgg
    14221 aagaagctaa attttctggt ggtctcgtcc tattgctaga cgaaattcat cgactagata
    14281 agaccaagca agacttcctc ttgcctctct tggaaagtgg actggtcatc atgattggag
    14341 caacgactga aaatcctttc ttctctgtca ctcctgccat tcgtagccgt gttcaaattt
    14401 tcgagttgga acctctgtct aaccaagacg tcaaagaggc cctgcagata gctctaagta
    14461 accctgaacg tggttttgat tttccaatag aactagatga ggatgcgctg gatttcatcg
    14521 caacctctac aaacggagac cttcgctctg cctttaactc actggacttg gctgttctct
    14581 ctacccctga gaatgacaag ggcattcgcc acatcacctt agacatcatg gaaaatagtc
    14641 ttcagagaag ctacatcact atggacaagg atggagacgg tcactatgat gttctatctg
    14701 ccctgcaaaa gtctatccgt ggctcagatg tggatgccag tctccactat actgcccgct
    14761 tgattgaggc tggggatctg cctagtctcg ctcgtcgctt gactgttatc gcctatgaag
    14821 atatcggctt agccaatcct gaggcccaga ttcataccgt gactgctctg gatgccgccc
    14881 agaagattgg gttcccagaa gcccgcattc tcattgccaa tgtcgtgatt gatttggccc
    14941 tttctccaaa atccaactca gcctatgtag ctatggataa ggcacttgct gacctcaaaa
    15001 catcagggca cttgcctatt ccgcgacacc tacgtgatgg gcactacagt ggaagcaagg
    15061 aactggggaa tgcccaagac tatctctatc cacacaacta tcctggaaat tgggtcaagc
    15121 aagactatct gccagaaaaa attcgtaatc atcactattt ccaagcagaa gatactggta
    15181 aatatgaacg ggctttggct caaagaaagg aagctatcga ccgtttgcga aaaatctgaa
    15241 atccttttca aaaaattgca ctttcctctt gatttttttt gaaaaagtgg tatcatataa
    15301 atatagaaac gctgtggtgt acgacttcac acttaagtgt tgaccgacta ttttttgtat
    15361 tattagggaa acaaaagtct tctaacagca tgtaggccgt ctcacacgga aacagcttca
    15421 gttagagcga gttgcccacc tgcttaattg cgcgggttca atacaaaccg tgaagtttcg
    15481 gcaccaatac agcttttttc tttgcctcct tagctcagct ggcagagcag cggactctta
    15541 atccgtgggt cacaggttcg atccctgtag ggggcatcta aatacaacag gaaaagtctt
    15601 ataatatagg gctttttttg cttaaataaa atttttttca aattctttag aaaactagtt
    15661 taaatcataa tccaacacca attttacaaa taccataaac taagcttata tacccaaaac
    15721 acaaaaagtc ctctttccac tattttagaa agagaacttt ttctttagga gaaataactt
    15781 aatttttaat caattcgtga tagctcagct ggcaccgtta agtaataagt tgcagtcaag
    15841 cttgcttcac cttgattgac aaaaatctcg atggaatttt tatctagaac aacttccaat
    15901 tctttagctt caatatctac ataccgtcga ctagtgtcct gttcttcttc acctagaatt
    15961 ttttgaataa gatggctacg atcaatgtaa acttgctgca cattactgtc ataaccaaat
    16021 tcaagataat ctgtatcatt tcctaagtgg taatgacaat ctttatctat ttggatttga
    16081 tattggcctt ttttaacagg gaattgtctt agtttgccat cttccaatct tagaattcta
    16141 ggtaaagtca tggcacatgc ccacttgtgt tcttggtcat gggttggaag ggtacgcccc
    16201 catgtctgca tccaagcaat caggatacga cgattttgat cgtccaacaa tgtttgaggc
    16261 gcatagaagt cttggccatg atcaatttct tgaactgatt ctgggataaa acgtttttct
    16321 ccccaatcta ccttacccgt gaacaaaagc gatgagttga tgttatgata tgagtctccc
    16381 tcacgctgat aacgcatggg tgacataata aggcaatctt tcccatctaa ctcgaagtaa
    16441 tctgggcatt cccacataaa gccttggtgt tctacccctt ttaaaaagat ggattcgaac
    16501 tgccattcta ctaggttatc ggaccctagt agaacgatac agcccacatt attcttgtgt
    16561 ttggcagcta ctacggagta atagcgtcca tctttttcaa agagttttgg atcacggaaa
    16621 tcagcagcaa tcaactcatc tggcaagtct gatccagttg caactggatt ttgggaaatc
    16681 ttttcaaagt gaatcccgtc atctgaaaat gccatatttt gcacttggcg gacaccggtt
    16741 ttttcttcga tatgcccagt gtacatgagc cagaggcgat catccttgac aatggcagag
    16801 cctgagaaac aaccatttcg gtcataatct tggtcaggag caagtgccac tggcaaatgc
    16861 tcccaagtca ccaagtcctt acttttagca tgtccccagt gcataggccc ccaaacacta
    16921 tcatatggat agaattgata aaagagatgg tattctccac gaaaatagac aaatccattt
    16981 ggatcattga tccaaccaat ctcagctgaa aaatgttctt caggcttata ttgagtatta
    17041 acgagatgtt tattttctgc tataaaacga ttggcttttt ctactgtaaa tgttttattt
    17101 atcataagta tatcctattt tattccagtt ccggaaccac ccagaccttg aacaatatat
    17161 ttctgagcga ctacatagac caaaatcaac ggaatcgttg aaatagttaa tacagccatt
    17221 acctgattga tataaactgg ttgagttgta ttaatagttg taattgcaac ctgcattgaa
    17281 aatttagaag aatctgtcaa aaccatcaat ggccagatat aatcattcca gcttgaaata
    17341 aatgataaaa caccaactgt agcaactgca ggtttagaca ttggaagcat aattctaaag
    17401 aaaattctaa cgatacttgc tccgtccatc tttgcagact caagaatctc ttctggaatt
    17461 gcaataaaga aattcctaaa taagtaaata ttaaatacac tcgccaatcc tggaataata
    17521 actgcaaaac gattattgac caaacctaag gaattgataa tggtaaattg tggaattaac
    17581 acagtttcca ctggaataat aagtaaagca agtaagaaac caaataaaat tttcttacct
    17641 gaaaaattga cttttgcaaa agcgaaaccg gccagtgcat tgacaataat agaaccaata
    17701 gcaaacgttc cagcataaaa aatgctgttc cctagatatg taaaaatact aaagcgctca
    17761 aatacttcct gataaggttt aaaccaatca gcgggattta aacttggtaa gaaggcttgc
    17821 caactagtca aatttttata aacatccgct tctggcttca tagctgaaac taccatccaa
    17881 accataggaa aaaggaagag tcctgccaat aaagttaaca gaatatattc taagattgtt
    17941 gttggtttaa atcgtttcat cttagtcatc ctccttcaga acgcgacgtt gtactaagct
    18001 aatcatacca attaacgttg taaatactaa agcgattgag ctagaatatc ctacaagacg
    18061 atcagtaaaa ccttgttgat aaatatagta caccatagta attgttgagt ttaatggccc
    18121 accttgcgtc ataaccattg gttgtacaat cagcttaaaa gcagaaatta aagttgttaa
    18181 caatacaaac agggctgttg gttttagtag gggcatcgtg atataacgaa actgagccca
    18241 ttttgagaat ccatctaatt cagcagcttc atagacatct tgtggaatat tctgcattcc
    18301 tcctaaaaat aaaagcatct gataacctgc accctgccaa gcagaaacaa aaacaattgc
    18361 atacatagct tgtttaggac tagtcaagaa aggttgagaa gcaataccta ccttatttaa
    18421 aatagcattt aataagccac tatttggatt taaaagataa agccaaagaa tagaaataac
    18481 taccaaggac atgacaactg gagcaaaaaa agccacttta aaaaacatat ttccttttcg
    18541 ctttttattg acaatcaaag ccattcctaa ggccgctccc aattgaactg gaataatcca
    18601 aacaacaaat ttcaaagtat tcaagaagct ctttaagaaa atcggatctt ttgttaatcg
    18661 aataaaattc tcaaatccaa caaattttct ttcatctggt gtcaacaaat aataatctgt
    18721 aaaagtgtaa taaatgacca ttccaactgg aattactaaa aagataccta ataaaattaa
    18781 agctggagct aaaaaactat aacctaatat gttatccttt attttttcac gtctttttgt
    18841 atacacaaca gtttctttac tcatatccat ctcctttaat catatatatc aaactaggct
    18901 attaacaaga aaggggaagg tagttccaaa cattttcctt ccaccttctt ttttacagat
    18961 tatttgagtg actgatcaat agcagtttgc atttcttttg tacgagtatc caagactttt
    19021 tgcacatttg gattttcttc ataatagcta atatcttgca ttgcttgttg aaaagctcga
    19081 gaaacctgag gatatgctac aacaactggg cgagcatgag ctgtttttga attttgttcc
    19141 atcaagaaac gcattggttc ggatacttta tctttgatat tttcaattgt agatttacga
    19201 attggaagga ccgaattccc caagctaata atttcacttg attctgtatt tgtagcaaat
    19261 ttaacaaatt cagatgcggc ctctttttta tcagattttg tcgtcacagc taattgccaa
    19321 ctacctgaag gggatactaa ttttttcgtc ttactagata ctgggtaagg aaggatacca
    19381 aaatcaatat ctttgtagtt tgtattcatg tcagcaatcg tccaagaacc actcaaaagc
    19441 attggatact ctcctgtttc aaaacctttt tcgactggac taacagttgt atagccttct
    19501 tttacaagat tttgaatgaa ttgaactgct tctacactct ctttggagtt gaagtatcct
    19561 tctgcctttg ttccatcttc gtttacgaca gaaccattat ttgaccaaat caacggcata
    19621 taagcatatg gcaacatttc atcgtttgaa ttaatacgaa aatcaattgc tggtttgtta
    19681 taatgatctt tcaatttttt agcaatcgta ttaaattcgt cccatgtcca tggcttttct
    19741 agcgttggaa gctctgattc cgcaattccg gcctctttga acattttttt attgtaataa
    19801 acaccaacat tcgattcaga aaatccaaat gcatagaatt tcccattata agttccctgt
    19861 tgtttaatac tgtccaaaac atcatccata ttattatctt ttagataatc atctagcgga
    19921 gtaattactt tagattttgc ataagctgcc gtatttggtc catcaagggt aataacatct
    19981 ggaagactat tagtcgtaat agcagcatta accttgtctt catatcctcc accactacca
    20041 ctacgaggaa tatactcagt tacaaccttg tacttacttt ttcctgattg attaaagtta
    20101 tcaacaactt tttgccaagc ttttccttca tttgtttcgt cagagaattg tacccagact
    20161 ttaatatcat ttgaagaact cgcttgtttt gagttagttc ctccactaca acctgcaagt
    20221 atagctaacg atagccccgc aacaacagat aacattgtac ctttacgcat cattttcctc
    20281 ctttttgaaa cgtttcattt tttatttatt ttttaaacaa gcttctagcc tatttttgaa
    20341 acgtttcatt tgttgattat attataacag cgctttcatt aattgtcaag cgctttttaa
    20401 attttttttg ttgttttatc tccccaaaaa tatgtgggaa ttacgattcg tttttctaga
    20461 atctcttctc gcttaatcat tttcagtatc attgcaacag attcttttgc catcatacca
    20521 atatcttgaa ctattgtaga cactagataa gattgatcga cagaagtttt taaaccatca
    20581 aacccaatta tctggtaatc atcaggtgct attttcccca gttctttcat aacactaata
    20641 actctcagag ccatcatatc atttattgta aatataccat caatttcttt atgagattgc
    20701 aaaaaaattc ttatctgatc ttcaggattt attaaaggtt ctttcatttc aaaattatag
    20761 acatctactc ctaattcctt agctttttct ctgaatcctt tacttctgag tatagtctca
    20821 ttctcataca tattaattga accaataaaa gcaaggtgct tattatccct tctaaccagt
    20881 tcctctgctg cagtttgtcc tcctttgtaa tttgctgaag taacatagca tacattttcc
    20941 gaaaaatgtc tatctatact tacaaacggt aaatcagata aaatatattt gtcaatatca
    21001 gaatatgtaa taccaataat tccatccact ttattttgtt tcaacatttc gatatattcg
    21061 atttcatttt gtgaatcgct atcagcgtta caaataaata atttataatt atattttaat
    21121 aactctttct caacatgata ggcaaactcc gaaaaaaatg gatgccatat gctcggaata
    21181 atcaaagcga tagtttctgt tctattcttt ttcatacctc gagcataatt atcagggata
    21241 tagtccaatg tttttatagc cctttgaact ttccttaaag ttacttcttt aatgcctttt
    21301 tctttattaa ttacacgtga aacagttcca acactaactc ctgcttctaa agcaacatct
    21361 ttcatggtaa ttgattttct ttgttctacc atattatcaa ctcctttcaa tatatagtat
    21421 catgcaaatg ctttttaagc aactatttct caatcatttt tggccagatc atttatccca
    21481 tcatgaataa aatcactcca attagctttt gaaaatactt caattttcat gtgtaaacat
    21541 ctacataaaa caggaaaagc cttggtttca tggctttttt cgtatcttct acaaaaaaag
    21601 caagagtttt agagggctat aaatctagat gtacattttt cttaaatgat tgaaggtctt
    21661 ttcttaacaa aaacacccta aaaattagac tttttctgtc taacttttga ggtacagttc
    21721 aaacgcgaaa tagcgttttt ttgttatttt tggttactca tctaatcgaa taaacatcat
    21781 ggcatttaac aagtatatga gtgagaccgt gtttatatta tttgaataga tgagtctctt
    21841 attttcaata ggaggaataa taaaattgga aataatgata tcataaggtg aatcttctaa
    21901 agattccttt gataattcta attcggtcca aacctccagt tcaaaattat tgctacagta
    21961 ataagaaagt gtctctgcaa cgaattttgc atgatactga tcaaaattac tcataactaa
    22021 aacctttagt ttaggctgat tttgtagcaa attaatcacc aaatgtttgg tatgagtgat
    22081 gaaggtataa gatagatgat ttaccatcat tgaactagaa caaacctcaa gagtctctaa
    22141 atagtgagaa agctcttttt ttatatctga aacaaatttt ggaaaaatat tttgaaagtt
    22201 cctgattgta ttcccttttt gatcaaataa aataaactca gtaaacaact cttgacgata
    22261 cagatgtgcg gtattatgca gatgccaaat cagattatcc ttattctcca tttcaatctg
    22321 atacttgact gaaatctgat caataaaatc actcaataga tggtaagatt tttcaacata
    22381 actatccttt tttacgcatt tcataaagag actttcatct atgaaaaaca ttttttgaaa
    22441 gtaagacaca aataattggc aaacaacttc ttcatctaaa gagatattgt attctgattc
    22501 aaaactctga gcaacacctt ctattccttc tgcctgcatt aaaaaatcca aactttggtc
    22561 gttaaaagaa tctttatcta cttccataaa atgaccaaac tttattctat ataggttcgt
    22621 aactaggagc aactttagca ttctatgcgt tgacaaattc attggaaagc ttgtttcctt
    22681 ataaaccaat tctaacaatt gagatagtgg ctctgatgaa aaattttcaa atggccattc
    22741 taggaaataa tatttttctg aaaaatattg tgcaaaaaag taacgaatgt ctctctcatt
    22801 tccaatgatt tgaacagggg tcagactgac ttcaaattga aattgccttt taatcacttt
    22861 attgatttgg ctaataatac gatagagcga agatgaactg atataaaatt ctttacaaat
    22921 actctcagct tgacaacctt cattaaagaa gatgaattct aaaatcgaaa aatgagttga
    22981 atgtttaaag aaatgatggt aaaccatttc aatatcacta tcatcggtat taataatgcg
    23041 tataccatta gtagaagaat gaaaaatcaa gtcaggaaaa gcagatttaa catgggatag
    23101 atcatctttg actgcacgtt ctgtacaatt taataactct gctagttcag aacgatgaaa
    23161 ccaacgttta tgttcaaata ataattctaa taattctaat tgcctatgac tttttttaga
    23221 taataaatct ctcatgaata tctttctctc tttataaatt atcggattaa acctcttgca
    23281 attataccac aaagaatagg tatagcatga tataacgact tttcctaaaa tcttttattt
    23341 cgtataataa cactacggag acaatatata aacaatt
//
LOCUS       DAVHSL010000032        21728 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000032 DAVHSL010000000
VERSION     DAVHSL010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.033"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(176..484)
                     /locus_tag="VVR39_001326"
                     /pseudo
     CDS             complement(176..484)
                     /locus_tag="VVR39_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            475..873
                     /locus_tag="VVR39_001327"
     CDS             475..873
                     /locus_tag="VVR39_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6030812.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEIANWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(1070..1990)
                     /gene="cysK"
                     /locus_tag="VVR39_001328"
     CDS             complement(1070..1990)
                     /gene="cysK"
                     /locus_tag="VVR39_001328"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU6030813.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(2275..2910)
                     /locus_tag="VVR39_001329"
     CDS             complement(2275..2910)
                     /locus_tag="VVR39_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU6030814.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGLLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2966..4264
                     /locus_tag="VVR39_001330"
     CDS             2966..4264
                     /locus_tag="VVR39_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6030815.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            4261..4923
                     /locus_tag="VVR39_001331"
     CDS             4261..4923
                     /locus_tag="VVR39_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU6030816.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            5002..5550
                     /gene="raiA"
                     /locus_tag="VVR39_001332"
     CDS             5002..5550
                     /gene="raiA"
                     /locus_tag="VVR39_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU6030817.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRLKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QITNVIYRREDGEIGLLEVKES"
     gene            5686..7659
                     /locus_tag="VVR39_001333"
     CDS             5686..7659
                     /locus_tag="VVR39_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU6030818.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLIEIVLNEIKEKEKEE"
     gene            7656..8108
                     /gene="rplI"
                     /locus_tag="VVR39_001334"
     CDS             7656..8108
                     /gene="rplI"
                     /locus_tag="VVR39_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU6030819.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            8151..9503
                     /gene="dnaB"
                     /locus_tag="VVR39_001335"
     CDS             8151..9503
                     /gene="dnaB"
                     /locus_tag="VVR39_001335"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU6030820.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9505..9771
                     /locus_tag="VVR39_001336"
     CDS             9505..9771
                     /locus_tag="VVR39_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030821.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9860..10978
                     /gene="cbpD"
                     /locus_tag="VVR39_001337"
     CDS             9860..10978
                     /gene="cbpD"
                     /locus_tag="VVR39_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU6030822.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     VKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSHSSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      11061..11163
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11234..11524
                     /locus_tag="VVR39_001338"
     CDS             11234..11524
                     /locus_tag="VVR39_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU6030823.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11487..12245
                     /locus_tag="VVR39_001339"
     CDS             11487..12245
                     /locus_tag="VVR39_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030824.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            12283..13290
                     /locus_tag="VVR39_001340"
     CDS             12283..13290
                     /locus_tag="VVR39_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6030825.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13290..14018
                     /locus_tag="VVR39_001341"
     CDS             13290..14018
                     /locus_tag="VVR39_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030826.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            14137..14595
                     /locus_tag="VVR39_001342"
     CDS             14137..14595
                     /locus_tag="VVR39_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU6030827.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            14597..17029
                     /locus_tag="VVR39_001343"
     CDS             14597..17029
                     /locus_tag="VVR39_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6030828.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMAHMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKANHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17671..18324
                     /gene="rr06"
                     /locus_tag="VVR39_001344"
     CDS             17671..18324
                     /gene="rr06"
                     /locus_tag="VVR39_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU6030829.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMILDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18321..19652
                     /gene="hk06"
                     /locus_tag="VVR39_001345"
     CDS             18321..19652
                     /gene="hk06"
                     /locus_tag="VVR39_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU6030830.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19735..20262
                     /locus_tag="VVR39_001346"
     CDS             19735..20262
                     /locus_tag="VVR39_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU6030831.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            20341..>21728
                     /locus_tag="VVR39_001347"
     CDS             20341..>21728
                     /locus_tag="VVR39_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU6030832.1"
                     /translation="MFASKNERKVHYSIRKFSIGVASVAVASLFMGSVVHATENEGTT
                     QVATSSNKANKSQTEHMKAAKQVDEYIKKMLQLDRRKHTQNVGLLTKLGAIKTEYLHG
                     LSVSKEKSEAELPSKIKAELDAAFENFKKDTLKPGEKVAEAKKKVEEAELELVKEEAK
                     EPRDEEKIKQAKEKVESKKAEATRLENIKTDRKKAEEEAKRKADAKLKEANVATSDQG
                     NPKGRGKRGVPGELATPDKKENDAKSSDSSVGEETLPSSSLKSGKKVTEAEKKVEEAE
                     KKAKDQKEEDRRNYPTNTYKTLDLEIAESDVKVKEAELELVKEEAKEPRDEEKIKQAK
                     EKVESKKAEATRLEKIKTDRKKAEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPK
                     PEKPAEQPKAEKTDDQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQEN
                     GMWYFYNTDGSMA"
BASE COUNT         6847 a         3592 c         4900 g         6389 t
ORIGIN      
        1 tagcttatga agggcttttc tatcactcca aaaatatagt agattgaaac tagaatagta
       61 cacctctgct tctaaaacat tgttagaaat cgatttgtcc tgttcttatt tcattttact
      121 ataaatccat cagaaagtcg tgatttctat tgaaatgagg actttctttt tatgctcatc
      181 tgttttcaaa aagcattcta gtccatctcc gattaacgat ggactttatc acctccttct
      241 ccagtccttg tataacatct tggagttgat tcatgacatc ttccaaagtt tgaaaggctt
      301 tattcttaaa tccacgttta cgaatctctt tccacacttg ttcaatgggg ttcatctctg
      361 gtgtgtatgg aggaataaag gtaaaaccaa tattagtcgg aatctttaag gtacttgatt
      421 tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa gcttgtgaaa
      481 gctcctattc ctaaagcccc tttggcgcat agccttggct cagcttctat tatcgctcac
      541 accatccatc agaagtttaa tctgaaggta cccaattatc gccaagaaga agattgggct
      601 aagatgggtt taccaatcac acgtaaggaa attgctaatt ggcatatcaa ggcgagtcaa
      661 tactatttgg agccccttta taacctcttg cgagagagac tattgacgca gtccttactt
      721 catgcggatg aaacttctta tagggtgcta gagagtgata gtcagctgac ttactattgg
      781 acttttttgt ctgggaaagc tgagaaacaa gggattacgc tttaccatca tgtcctaatc
      841 gatttgttca tatcttattt caatccatta taaatagtga gaaatattta tcctatcttc
      901 tagaatgtct tccaaacgtg gaaactctcg taaacaaaga ggttttagag gcctatttac
      961 catggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc
     1021 gtgagttctc tagtctggag atttttcaat atacttcgtt attggatggt tacaattcat
     1081 aaagtgctgt agagagataa cgttcaccgt tatctggtgc tagggcaagg acttttttac
     1141 ctgtacctaa ttttttggca acctcgatgg ctccgtagat agctgcagct gaggaaatcc
     1201 ctacaaggaa gccttctttt ccaccaattt cacgtccgag tgcaagagcg tcatctgatg
     1261 ttacacgaac gataccatca taggctttag tatcaagtgt atcaggaata aatccagctg
     1321 agataccttg aattttgtga ggaccaggtt tttcaccaga tagaatagca gattcatctg
     1381 cttctactgc aaaaacttga atgttagaat tttctgattt gagtgcatga gaaacaccag
     1441 aaatcgttcc accggtacct actccagcaa caaaggcatc taatccatct ttaccgaaag
     1501 cagctagtat ctcagctcct gttgttcttt cgtgtacttc tggattagct ggattgtcaa
     1561 attgaagagg aaggaaacca tcacgttcag cagcgatttc ttgagcctta gcaatagcac
     1621 ctttcattcc ctcgctacca ggagttagga cgagttcagc accataagct tggataattt
     1681 tacgtcgttc tacactcata gtttcaggca taacgatgac gactttatac cctttagcag
     1741 cacctaccca tgaaagtcca ataccagtgt ttccacttgt tgcttcaaca atagtagaac
     1801 caggtttcag aataccatct tgttcagctt tttcaatcat gctaagggca atacggtctt
     1861 ttacagatga accaggatta aatgcttcaa gctttatata gacgtctgca gcaccttctg
     1921 gcacgatgtt gttaagttta acaatcggtg tttgaccgat taattcagta atgttgttat
     1981 aaatagacat acgaatacct ctttgtataa gatatcttta gtataacgct atccatacca
     2041 tttgtaaaat atagaaatcc tatcgaagcg ataggatttc tatatatcat agatcaaagt
     2101 cattaatttt caagtgattg cgttcagcta attctagtaa ataggtgtga aggaaaacga
     2161 tatcaggttt cgtttgaatt gcttcatttt ctagtatatt ttggtacgca tctttttatt
     2221 ttgctcgcta aagtagttgt gagaatgtca acgaaacgct gtattattca ttgtttacac
     2281 taagtttaca ggaacttcaa cctctcgtaa accttggtca gttaaagtga cttttccatt
     2341 aaaaaactcc acaagtgcag ctttaatagt ttctttttct tctttatcaa cataaatcat
     2401 cgtatcgact tgatctgtaa agtttgtatc cagctccatg agatcatgtt ctttaaggaa
     2461 gttactgtac tcttggtact gagcataaga catttgaata gcaatgccag cctgttcttt
     2521 tatttcaata ataccaattt ctttgacagc taaggcgaca ctgccggcgt aagcacgaat
     2581 tagtcctcca gcgcctagtt taataccacc aaagtagcgt gtcacgacca cacagacatt
     2641 ggtgagattg tgattttcta gtagcccaag catgggaaca ccagcagtac cactaggctc
     2701 accatcatca cttgtacgtt taatttcact acgttctcca ataataaagg cagagcagtt
     2761 atgtgtcgct ttgtagtgtt cttttttgat ggcagtaatg aagtcacgag cctcttcttc
     2821 gctataaaca cgcttggcat ggcagataaa gcgagatttt ttgatttctt cttggacttg
     2881 gtcgtcctct ttaattgttc taaattccat gatttaattg tactaaaaaa tcatctaaag
     2941 tgctagtttt tacgaataaa gaagtatgaa agtaaattta gattatctcg gtcgtttatt
     3001 tactgagaat gaattaacag aagaagaacg tcagttggcg gagaaacttc cagcaatgag
     3061 aaaggagaag gggaaacttt tctgtcaacg ttgtaatagt actattctag aagaatggta
     3121 tttgcccatc ggtgcttact attgtcgaga gtgcttgctg atgaagcgag tcagaagtga
     3181 tcaaacttta tactattttc cgcaggagga ttttccgaag caagatgttc tcaaatggcg
     3241 cggccaatta actccttttc aagagaaggt gtcagaggga ctgcttcaag cagtagacaa
     3301 gcaaaagcca accttagttc atgcggtaac aggagctgga aagacagaaa tgatttatca
     3361 agtagtggct aaagtgatca atgcgggtgg tgcagtgtgt ttggctagtc ctcgcataga
     3421 tgtttgtttg gagctgtata agcgcctgca acaggatttt tcttgcggga tagctttgct
     3481 acatggagaa tcggaacctt attttcgaac accactagtt gttgcaacaa cccatcagtt
     3541 attgaagttt tatcaagctt ttgatttgct gatagtggat gaagtagatg cttttcctta
     3601 tgttgataat cccacgcttt accatgctgt caagaatagt gtaaaggaga atggattgag
     3661 aatcttttta acagcgactt cgaccaatga gttagataaa aaggtccgtt taggagaact
     3721 aaaaagactg aatttaccga gacggtttca tggaaatccg ttgattattc caaaaccaat
     3781 ttggttatcg gattttaatc gctacttaga caagaatcgt ttgtcaccaa agttaaagtc
     3841 ctatattgag aagcagagaa agacagctta tccgttactc atttttgctt cagaaattaa
     3901 gaaaggggag cagttagaag aaatcttaca ggagcaattt ccaaatgaga aaattggctt
     3961 tgtatcttct gtaacagagg atcgattaga gcaagtacaa gcttttcgag atggagaact
     4021 gacaatactt atcagtacga caatcttgga gcgtggagtt accttccctt gtgtggatgt
     4081 tttcgtagta gaggccaatc atcgtttgtt taccaagtct agtttgattc agattggtgg
     4141 acgagttgga cgaagcatgg atagaccgac aggagatttg cttttcttcc atgatgggtt
     4201 aaatgcttca atcaagaagg cgattaagga aattcagatg atgaataagg aggctggtct
     4261 atgaagtgct tgttatgtgg gcagactatg aagactgttt taacttttag tagtctctta
     4321 cttctgagga atgatgactc ttgtctttgt tcagactgtg attctacttt tgaaagaatt
     4381 ggggaagaga actgtccaaa ttgtatgaaa acagagttgt caacaaagtg tcaagattgt
     4441 caactttggt gtaaagaggg agttgaagtc agtcatagag cgatttttac ttacaatcaa
     4501 gctatgaagg attttttcag tcggtataag tttgatggag acttcctgtt aagaaaagtt
     4561 ttcgcttcat ttttaagtga ggagttgaaa aagtacaaag agtatcaatt tgttgtaatt
     4621 cccctaagtc ctgatagata tgctaataga ggatttaatc aggttgaggg cttggtagag
     4681 gcagcaggct ttgagtatct ggatttatta gagaaaagag aagagagagc cagttcttct
     4741 aaaaatcgtt cagagcgctt ggggacagaa cttcctttct ttattaaaag tggagtcact
     4801 attcctaaaa aaatcctact tatagatgat atctatacta caggagcaac tataaatcgt
     4861 gttaagaaac tgttggaaga agctggtgct aaggatgtaa aaacattttc ccttgtaaga
     4921 tgaggaaaaa tttgcaaaaa tagaatgaaa gcgttataat aaaatcataa aaacaaaaat
     4981 gtttagaaag aaggtactca tatgattaaa tatagtatcc gtggtgaaaa cctagaagta
     5041 acagaagcaa ttcgtgatta tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa
     5101 ccagaacaag agttggatgc ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa
     5161 gtggaagtaa cgattccgct tggatctatt actctccgcg cagaagatgt atctcaagat
     5221 atgtatggtt caattgacct tgtaactgat aaaattgaac gtcagattcg taaaaataaa
     5281 acaaaaatcg agcgtaaaaa taaaaataag gtagcaactg gtcaattatt tacagatgct
     5341 ttggtggaag attcaaatgt tgtccagtct aaagttgttc gtttaaaaca aattgattta
     5401 aaaccaatgg atttggaaga agcaattcta caaatggatt tattggggca tgatttcttt
     5461 atctatgtgg atgttgaaga tcagataacc aatgtgattt atcgtcgtga ggatggcgaa
     5521 attggtttgt tagaggttaa agaatcttaa tttcaatatg tgtaaaggta ggtttactga
     5581 attgtaaact acctttttct tataattgat agaattactg attacacttt taaaaagtcg
     5641 ctttttgagg ggtattatgg tataatgggt gccaagaggt tttgaatgaa aaaattttat
     5701 gtaagtccaa tttttcctat tctagtagga ttgattgcgt ttggagtctt atccactttc
     5761 attatttttg ttaataataa tctgttgacg gttttaattt tgtttctttt tgtaggaggc
     5821 tatgtttttt tatttaagaa actgagagtg cattatacaa ggagtgatgt agaacagata
     5881 cagtatgtaa accaccaagc ggaagaaagt ttgacatctc tattggaaca aatgcctgta
     5941 ggtgttatga aattgaattt atcttctgga gaggttgagt ggtttaatcc ctatgctgaa
     6001 ttgattttga ccaaggaaga tggtgatttt gatttagaag ctgttcaaac gattatcaag
     6061 gcttcagtag gaaatccgtc tacttatgcc aagcttggtg agaagcgtta tgctgttcat
     6121 atggatgctt cttccggtgt tttgtatttt gtagatgtat ccagggaaca agccataaca
     6181 gatgaattgg taacaagtcg accagtgatt gggattgtct ctgtggataa ttatgatgat
     6241 ttggaggatg caacttctga gtcagatatt agtcaaatca atagttttgt agctaatttt
     6301 atatcagagt tttcagaaaa atacatgatg ttttctcgtc gggtaagtat ggatcgattt
     6361 tatctattta ctgactacac ggtgcttgag ggcttgatga atgataaatt ttctgttatt
     6421 gatgctttca gagaagagtc gaaacagaga cagttgccct tgaccttaag tatgggattt
     6481 tcttatggcg atggaaatca tgatgagata gggaaagttg ctttgctcaa tttgaacttg
     6541 gctgaagtac gtggtggcga ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca
     6601 gtttattttg gtggtgggtc tgctgcttca atcaagcgta cacggactcg tacgcgcgct
     6661 atgatgacag ctatttcaga taagattcgg agtgtagatc aggtttttgt agtcggtcac
     6721 aaaaatttag acatggatgc tttgggctct gctgtaggta tgcagttgtt cgccagcaat
     6781 gtgattgaaa atagctatgc tctttatgat gaagaacaaa tgtctccaga tattgaacga
     6841 gctgtttcat tcatagaaaa agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg
     6901 gggatggtga ccaatcgttc tttgttgatt cttgtagacc attcaaagac agccttaaca
     6961 ttatcaaaag aattttatga tttatttacc caaaccattg ttattgacca ccatagaagg
     7021 gatcaggatt ttccagataa tgcggttatt acttatatcg aaagtggtgc aagtagtgcc
     7081 agtgagttgg taacggaatt gattcagttc cagaattcta agaaaaatcg tttgagtcgt
     7141 atgcaagcaa gtgttttgat ggctggtatg atgttggata ctaaaaattt cacctcgcga
     7201 gtaactagtc ggacatttga tgttgctagc tatctcagaa cgcgcggaag tgatagtatt
     7261 gctatccagg aaatcgctgc gacagatttt gaagaatatc gtgaggtcaa tgaacttatt
     7321 ttacaggggt gtaaattagg ttcagatgta ctaatagcag aggctaagga cacgaaatgc
     7381 tatgatacag ttgttattag taaggcagca gatgccatgt tagccatgtc aggtattgaa
     7441 gcgagttttg ttcttgcgaa gaatacacaa ggatttatct ctatctcagc tcgaagtcgt
     7501 agtaaactga atgtacaacg gattatggaa gagttaggcg gtggaggcca ctttaatttg
     7561 gcagcagctc aaattaaaga tgtaaccttg tcagaagcag gtgaaaaact gatagaaatt
     7621 gtattaaatg aaataaagga aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg
     7681 ttaaaggaaa aggtaaaaaa ggcgaaatta aggaagtacc aacagggtat gcgcaaaact
     7741 ttcttatcaa aaagaatcta gccaaagaag cgactgctca agctgtaggt gaacttcgtg
     7801 gtaaacaaaa atcggaagaa aaagctcacg ctgagatgat tgcagaagga aaagcaatta
     7861 aagcacaact tgaagcagaa gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg
     7921 gtcgtacctt tggttctatt accaataaga agattgcaga agaattgcaa aagcaatttg
     7981 gaattaagat tgataaacgt catattcaag tacaagctcc gattcgagcg gttggtttga
     8041 ttgatgtgcc agtgaaaatc tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag
     8101 aaggataagt ttacactttc ttgacaagat tgtaaaagaa gggaagtctg atggcagaag
     8161 tagaagagtt acgagtacaa cctcaagata tcttagctga gcaatccgtt ttaggggcta
     8221 tctttattga tgagagtaaa cttgtttttg tgcgagaata cattgagtct cgggactttt
     8281 ttaagtatgc ccatcgtttg attttccaag ccatggtcga tttatccgat cgtggtgatg
     8341 ccatagatgc aacaacggtt cgtactatcc ttgataatca aggtgattta cagaatattg
     8401 gtggcttgtc ttacttggtt gagattgtta attctgtgcc aacttctgct aatgcggagt
     8461 attatgctaa gattgttgca gaaaaagcaa tgctacgtcg tttaattgcc aagttgacag
     8521 agtctgtcaa ccaagcttac gaagcgtcac aaccagctga tgaaattatt gctcaggcag
     8581 aaaaagggtt gattgatgtc agtgaaaatg caaatcgaag cgggtttaag aacattcgag
     8641 atgtgttgaa tctcaacttt ggaaatctgg aagctcgctc gcaacaaacg accgatatta
     8701 caggtattgc gacaggttat cgtgatttgg atcatatgac aacaggactt catgaggagg
     8761 agttgattat cttagcagct cgtccagcag ttggtaagac agcatttgcc ttgaatatcg
     8821 ctcagaacat tgggactaag ttggacaaaa cggttgctat tttttcactc gaaatgggtg
     8881 cggaaagctt ggtagatcgt atgttagctg cagaaggctt ggtggagtca cattctatcc
     8941 gtacagggca attgacagat gaggagtggc aaaaatatac tattgctcag ggtaatctag
     9001 ctaacgccag tatctatatc gatgatacgc caggtattcg gattacagag attcgttctc
     9061 gttctcgtaa attggctcaa gaaactggaa atcttggttt gattttgata gactatttgc
     9121 aacttatcac gggaactggt cgagaaaatc gtcaacaaga agtttctgaa atttctcgtc
     9181 agttgaaaat actagccaag gaattgaagg ttccagtaat cgctctgagt cagctttctc
     9241 gtggtgtaga acaacgtcag gacaagagac cagtcttgtc tgatattcgt gaatctgggt
     9301 ctattgagca ggacgctgat atcgtagctt ttctctatcg cgatgactac tatgaacgtg
     9361 gtggtgaaga agaggagggt atcccaaata ataaggtgga agttattatc gagaaaaacc
     9421 gtagtggagc tcgtggaaca gtggaattga ttttccaaaa agaatacaat aaattttcaa
     9481 gtatctcaaa gagggaggca taagatgtca gatgcattta cagatgtagc caagatgaaa
     9541 aaaatcaaag aagaaatcaa ggcacatgag ggacaagtcg tagaaatgac tttggagaat
     9601 ggtcgtaagc gccaaaaaaa tagattgggt aagctaattg aagtttatcc atctctattt
     9661 attgtggagt ttggggatgt ggaaggagat aaacaagtta atgtttacgt tgaatccttt
     9721 acttactcag atattcttac agaaaagaat ttgattcatt atcttgacta aagtgagaaa
     9781 ttttctcact ttttcttttt tctccgaata atttaggtga aggcaatcat cgctttatat
     9841 tatttttcaa ggaggaagaa tgaaaatttt accgtttata gcaagaggaa caagttatta
     9901 cttgaagatg tcagttaaaa agcttgttcc ttttttagta gtaggattga tgctagcagc
     9961 tggtgatagt gtctatgcct attccagagg aaatggatcg attgcgcgtg gggatgatta
    10021 tcctgcttat tataaaaatg ggagccagga gattgatcag tggcgcatgt attctcgtca
    10081 gtgtacttct tttgtagcct ttcgtttgag taatgtcaat ggttttgaaa tgccggcagc
    10141 ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg gaaggttatc gtgtagataa
    10201 tacaccgacg attggttcca ttacttggtc tactgcagga acttatggtc atgttgcctg
    10261 ggtgtcaaat gtaatgggag atcagattga gattgaggaa tataactatg gttatacaga
    10321 atcctataat aaacgagttg taaaagcaaa cacgatgaca ggatttattc attttaaaga
    10381 tttggatggt ggcagtgttg ggaatagtca atcctcagct tcaacaggcg gaactcatta
    10441 ttttaagacc aagtctgcta tcaaaactga acccctagtt agtgcaactg tgattgatta
    10501 ctattatcct ggggagaagg ttcattatga tcagatactt gaaaaagacg gctacaagtg
    10561 gttgagttat acggcttata acggaagtcg tcgctatata cagctagagg gagtgacttc
    10621 ttcacaaaat tatcagaatc aatcaggaaa catctctagc tatggatccc atagtagttc
    10681 aactgtcggt tggaagaaaa taaatggtag ttggtatcat ttcaaatcaa atggttctaa
    10741 atcaacagga tggctgaaag acggttctag ctggtattat ttgaaattat ctggtgaaat
    10801 gcagacagga tggttaaagg agaatggctc gtggtattat ctgggtagtt caggggcaat
    10861 gaaaacaggc tggtaccagg tctctggtaa gtggtattat tcttactctt caggcgcctt
    10921 agctgttaat acgacggtgg atggctacag agtaaacagt gatggagaac gagtatagaa
    10981 aattggagta ggagaaattt cctgctcttt tctgtaagca gtttccttga catttttctt
    11041 attttgcgct atcatatata catataatat atgggagtct gtgtacagtc tgagaggaag
    11101 tgttaaactt cgaccgcacc tgatctgggt aatgccagcg gagggaacga tacttagtct
    11161 aattttgcac cttttccatg tatggtaaag gtttttcttt ttttaaaaag gaaaacgaga
    11221 agaggaggtt cttatgaaag caagcattgc cttgcaagtt ttacccctag tacaggggat
    11281 tgatcggata gctgttattg atcaggtcat tgcttatctg caaactcaag aagtgacgat
    11341 ggtagtgaca ccatttgaaa cggtcttgga aggggagttt gatgagctta tgcgcattct
    11401 aaaagaagcg ctggaagtgg cagggcagga ggcagacaat gtctttgcca atgtcaaaat
    11461 aaatgtagga gagattttaa gtattgatga gaaacttgag aagtatactg agacgacaca
    11521 ttagtctatt gggctttctc ggagtattgt caatctggca gttagcaggt tttcttaaac
    11581 ttctccccaa gtttatcctg ccgacacctc ttgaaattct ccagcccttt gttcgtgaca
    11641 gagaatttct ctggcaccat agctgggcga ccttgagagt ggctttactg gggctgattt
    11701 tgggagtttt gattgcctgt cttatggctg tgctcatgga tagtttgact tggctcaatg
    11761 acctgattta ccctatgatg gtggtcattc agaccattcc gaccattgcc atagctccta
    11821 tcctggtctt gtggctaggt tatgggattt tgcccaagat tgtcttgatt atcttaacaa
    11881 caacctttcc catcatcgtt agtattttgg acggttttag gcattgtgac aaggatatgc
    11941 tgactttgtt tagtctgatg cgagcaaacc cttggcaaat cctgtggcat tttaaaatcc
    12001 cggttagcct gccttacttt tatgcaggtc tgagggtcag tgtctcctac gcctttatca
    12061 caactgtggt atctgagtgg ttgggaggtt ttgaaggtct tggtgtttat atgattcagt
    12121 ctaaaaaact gtttcagtat gataccatgt ttgccattat tattctggtg tcgattatca
    12181 gtcttttggg tatgaagctg gtcgatatca gtgaaaaata tgtgattaaa tggaaacgta
    12241 cttaaaatag agcgtttttg aaaaagaaaa gaggaaatca aaatgaagaa aacatggaaa
    12301 gtgtttttaa cgcttgtaac agctcttgta gctgttgtgc ttgtggcctg tggtcaagga
    12361 actgcttcta aagacaacaa agaggcagaa cttaagaagg ttgactttat cctagactgg
    12421 acaccaaata ccaaccacac agggctttat gttgccaagg aaaaaggtta tttcaaagaa
    12481 gctggagtgg atgttgattt gaaattgcca ccagaagaaa gttcttctga cttggttatc
    12541 aacggaaagg caccatttgc agtgtatttc caagactaca tggctaagaa attggaaaaa
    12601 ggagcaggaa tcactgccgt tgcagctatt gttgaacaca atacatcagg aatcatctct
    12661 cgtaaatctg ataatgtaag cagtccaaaa gacttggttg gtaagaaata tgggacatgg
    12721 aatgacccaa ctgaacttgc tatgttgaaa accttggtag aatctcaagg tggagacttt
    12781 gagaaggttg aaaaagtacc aaataacgac tcaaactcaa tcacaccgat tgccaatggc
    12841 gtctttgata ctgcttggat ttactacggt tgggatggta tccttgctaa atctcaaggt
    12901 gtagatgcta acttcatgta cttgaaagac tatgtcaagg agtttgacta ctattcacca
    12961 gttatcatcg caaacaacga ctatctgaaa gataacaaag aagaagctcg caaagtcatc
    13021 caagccatca aaaaaggcta ccaatatgcc atggaacatc cagaagaagc tgcagatatt
    13081 ctcatcaaga atgcacctga actcaaggaa aaacgtgact ttgtcatcga atctcaaaaa
    13141 tacttgtcaa aagaatacgc aagcgacaag gaaaaatggg gtcaatttga cgcagctcgc
    13201 tggaatgctt tctataaatg ggataaagaa aatggtatcc ttaaagaaga cttgacagac
    13261 aaaggcttca ccaacgaatt tgtgaaataa tgacagaaat tagactagag cacgtcagtt
    13321 atgcctatgg tcaggagagg attttagagg atatcaacct acaggtgact tcaggcgaag
    13381 tggtttccat cctaggccca agtggtgttg gaaagaccac cctctttaat ctaatcgctg
    13441 ggattttaga agttcagtca gggagaattg tccttgatgg tgaagaaaat cccaaggggc
    13501 gcgtgagtta tatgttgcaa aaggatctgc tcttggagca caagacggtg cttggaaata
    13561 tcattctgcc cctcttgatt caaaaggtgg ataaggcaga agctatttcc cgagcggata
    13621 aaattcttgc gaccttccag ctgacagctg taagagacaa gtatcctcat gaacttagcg
    13681 gtgggatgcg ccagcgtgta gccttactcc ggacctacct ttttgggcac aagctctttc
    13741 tcttagatga ggcctttagc gccttggatg agatgacaaa gatggaactc cacgcttggt
    13801 atcttgagat tcacaaacag ttgcagctaa caaccctgat catcacgcat agtattgagg
    13861 aggccctcaa tctcagcgac cgtatctata tcttgaaaaa tcgccctggg cagattgttt
    13921 cagaaattaa actagattgg tctgaagatg aggacaagga agtccaaaag attgcctaca
    13981 aacgtcaaat cttggcagaa ttaggcttag ataagtagaa aaatagggag ttggtgaaga
    14041 ttatccttta ccagcgccct ttttctttta aaaatgagaa aatttcggta taatagtcaa
    14101 acaaggtcaa ggtttaaaga gagaggtggg tttgttatga gatttaaaaa tacatcggat
    14161 catattgagg cctacatcaa ggcgatttta gatcaatctg gtatcgtgga gttgcaacgg
    14221 agtcagttgg cagatacctt tcaggttgtt cctagtcaga ttaactacgt gatcaagaca
    14281 cgctttacgg aaagtagagg ctacttggtt gaaagtaagc gtggtggcgg aggctacatt
    14341 cgtataggac ggattgagtt ttctagtcat catgaaatgc tccgggagct gctttactcg
    14401 attggtgagc gagtcagtca agaaatttat gaggatattc tccagctttt ggttgagcag
    14461 gaattgatga ccaagcagga gatgaatttg ctagaatcag tagctttgga tcgcgtttta
    14521 ggagaagaag ctccagttgt tcgagcaaac atgctacgtc aggtcataca agaggtagat
    14581 agaaaaggga agtaagatga actattcaaa agcattgaat gaatgtatcg aaagtgccta
    14641 catggttgct ggacattttg gagctcgtta tctagagtcg tggcacttgt tgattgccat
    14701 gtctaatcac agttatagtg tagcaggggc aactttaaat gattatccgt atgagatgga
    14761 ccgtttagaa gaggtggctt tggaactgac tgaaacggac tatagccagg atgaaacctt
    14821 tacggaattg ccgttctccc gtcgtttgca ggttcttttt gacgaagcag agtatgtagc
    14881 gtcagtggtc catgctaagg tgctagggac agagcacgtc ctctatgcga ttttgcatga
    14941 tggcaatgcc ttggcaactc gtatcttgga gagggctggt ttttcttatg aagacaagaa
    15001 agatcaggtc aagattgctg ctcttcgtcg aaatttagaa gaacgggcag gctggactcg
    15061 tgaagatctc aaggctttac gccaacgcca tcgtacagta gctgacaagc aaaattctat
    15121 ggcccatatg atgggcatgc cgcagactcc tagtggtggt ctcgaggact atacgcatga
    15181 tttgacagag caagcgcgtt ctggcaagtt agaaccagtc atcggtcggg acaaggaaat
    15241 ctcacgtatg attcaaatct tgagccgtaa gactaagaac aaccctgtct tggttgggga
    15301 tgctggtgtc gggaaaacag ctctggcgct tggtcttgcc cagcgtattg ccagtggtga
    15361 cgtgcctgcg gaaatggcta agatgcgcgt gttagaactt gatttgatga atgtcgttgc
    15421 agggacacgc ttccgtggtg actttgaaga acgcatgaat aatatcatca aggatattga
    15481 agaagatggc caagtcatcc tctttatcga tgaactccac accatcatgg gttctggtag
    15541 cgggattgat tcgactctgg atgcggccaa tatcttgaaa ccagccttgg cgcgtggaac
    15601 tttgagaacg gttggtgcca ccactcagga agaatatcaa aaacatatcg aaaaagatgc
    15661 ggcactttct cgtcgtttcg ctaaagtgac gattgaagaa ccaagtgtgg cagatagtat
    15721 gactatttta caaggtttga aggcgactta tgagaaacat caccgtgtac aaatcacaga
    15781 tgaagcggtt gaaacagcgg ttaagatggc tcatcgttat ttaaccagtc gtcacttgcc
    15841 agactctgct atcgacctct tggacgaagc agcagcaaca gtgcaaaata aggcaaatca
    15901 tgtaaaagca gacgattcag atttgagtcc agctgacaag gccctgatgg atggcaagtg
    15961 gaaacaggca gcccagctaa tcgcaaaaga agaggaagta cctgtctaca aagacttggt
    16021 gacagagtct gatattttga ccaccttgag tcgcttgtca ggaatcccag ttcaaaaact
    16081 gactcaaacg gatgctaaga agtatttaaa tcttgaagca gaactccata aacgtgtcat
    16141 cggtcaagat caagctgttt caagtattag tcgtgccatt cgccgtaatc agtcaggaat
    16201 tcgcagtcat aagcgtccga ttggttcctt tatgttccta ggacctacag gtgtcgggaa
    16261 aactgaatta gccaaggctc tggcagaagt tctttttgac gacgaatcag cccttatccg
    16321 ctttgatatg agtgagtata tggagaaatt tgcagctagt cgtctcaacg gagctcctcc
    16381 aggctatgta ggatatgaag aaggtgggga gttgacagag aaggttcgca ataaacccta
    16441 ttccgttctc ctctttgatg aggtagagaa ggcccaccca gatatcttta atgttctctt
    16501 gcaggttctg gatgacggtg tcttgacaga tagcaaggga cgcaaggtcg atttttcaaa
    16561 taccattatc attatgacat cgaatctagg tgcgactgcc cttcgtgatg ataagactgt
    16621 tggttttggg gctaaggata ttcgttttga ccaggaaaat atggaaaaac gcatgtttga
    16681 agaactgaaa aaagcttata gaccggaatt catcaaccgt attgatgaga aggtggtctt
    16741 ccatagccta tctagtgacc atatgcagga agtggtgaag attatggtca agcctttagt
    16801 ggcaagtttg gctgaaaaag gcattgactt gaaattacaa gcttcagctc tgaaattgtt
    16861 agcaaatcaa ggatatgacc cagagatggg agctcgccca cttcgcagaa ccctgcaaac
    16921 agaagtggag gacaagttgg cagaacttct tcttaaggga gatttagtgg caggcagcac
    16981 acttaagatt ggtgtcaaag caggccagtt aaaatttgat attgcataaa agaataaaag
    17041 tatcagcatc tgaccataag tcacagtgga gtgaaactca atgaaaatca aagagcaaac
    17101 taggcagcta gccgcaggtt gctcaaaaca ctggtttgag gttgcagata gagctgacgt
    17161 ggtttgaaga gattttcgaa gagtatgaaa ctaaaaccta tagcttctaa acgatccgtg
    17221 gttttcacca ttcaacacaa aattcatatg tttattaccc tccgtcgtat ttgtcttaga
    17281 gcgtgtgtag tagaaaaaga gcagtcttat ctgaaatttt tattctttca aaagagacct
    17341 gtttcttttt tgcatgtcaa atccgttcta gctggtattt gaaaaatcaa actaatattc
    17401 aataaaaatc aaagaacaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga
    17461 ggttgtagat agagctgacg tagtttgaag agattttcga agagtataag ctgcaagatg
    17521 aatgattttc ttgtattgac gttgttgttg acaaaaagta gcggataaat gaaatccatt
    17581 ccattatcat agatgatagg ctggtaggaa attttcaaat agcatacagg aaatagatgt
    17641 atggagttct ggtagtagaa agggagagag atgaacattt tagttgcaga tgacgaggaa
    17701 atgattagag aaggaattgc agcatttctg acagaagagg gttatcatgt cattatggct
    17761 aaggatggac aagaggtctt ggaaaaattt caagatctcc ctatccatct catgatattg
    17821 gatttaatga tgcctaggaa gagtggtttt gaagtgttaa aagaaatcaa tcaaaagcac
    17881 gatattcctg tcatcgtctt gagtgctctg ggagatgaaa ctactcagtc acaggtattt
    17941 gatctctatg ctgatgatca tgtgacaaaa cctttttctt tggtactgct tgtcaagcgt
    18001 attaaggcgc ttatcagacg ttactacgtc atagaggata tttggcgata tcaggatgta
    18061 acagtggatt ttacctctta caaagcacat tataaaaatg aagaaattga tctcaaacca
    18121 aaggaattac tggtactaaa gtgtttgatt cagcataaaa atcaagtttt aagtagagag
    18181 cagatattgg aagaaatttc aaaagatgta gctgatttac cttgtgatag ggtcgttgat
    18241 gtctatattc gtactcttcg caaaaaatta gctttagatt gtatcgtgac tgtgaaaaat
    18301 gttggatata agattagctt atgataaaaa atcctaaatt attaaccaag tcttttttaa
    18361 gaagttttgc aattctaggt ggtgttggtc tagtcattca tatagctatt tatttgacct
    18421 ttccttttta ttatattcaa ctggaggggg aaaagtttaa tgagagcgca agagtgttta
    18481 cggagtattt aaagactaag acatctgatg aaattccaag cttactccag tcttattcaa
    18541 agtccttgac catatctgct caccttaaaa gagatattgt agataagcgg ctccctcttg
    18601 tgcatgactt ggatattaaa gatggaaagc tatcaaatta tatcgtgatg ttagatatgt
    18661 ctgttagtac agcagatggt aaacaggtaa cagtgcaatt tgttcacggg gtggatgtct
    18721 acaaagaagc aaagaatatt ttgcttttgt atctcccata tacatttttg gttacaattg
    18781 ctttttcctt tgttttttct tatttttata ctaaacgctt gctcaatcct cttttttaca
    18841 tttcagaagt gactagtaaa atgcaagatt tggatgacaa tattcgtttt gatgaaagta
    18901 ggaaagatga agttggtgaa gttggaaaac agattaatgg tatgtatgag cacttgttga
    18961 aggttattca tgagttggaa agtcgtaatg agcaaattgt aaaattgcaa aatcaaaagg
    19021 tttcctttgt ccgcggagca tcacatgagt tgaaaacccc tttagccagt cttagaatta
    19081 tcctagagaa tatgcagcat aatattggag attacaaaga tcatccaaaa tatattgcaa
    19141 agagtataaa taagattgac cagatgagcc acttattgga agaagtactg gagtcttcta
    19201 aattccaaga gtggacagag tgtcgtgaga ccttgactgt taagccagtt ttagtagata
    19261 ttttatcacg ttatcaagaa ttagctcatt caataggtgt tacaattgaa aatcaattga
    19321 cagatgctac cagggtcgtc atgagtctta gggcattgga taaggttttg acaaacctga
    19381 ttagtaatgc aattaaatat tcagataaaa atgggcgcgt aatcatatcc gagcaagatg
    19441 gctatctctc tatcaaaaat acatgtgcgc ctctaagtga ccaagaacta gaacatttat
    19501 ttgatatatt ctatcattct caaatcgtga cagataagga tgaaagttcc ggtttgggtc
    19561 tttacattgt gaataatatt ttagaaagct atcaaatgga ttatagtttt ctcccttatg
    19621 aacacggtat ggaatttaag attagcttgt agacagatta gttttttatt aaagttcata
    19681 tagggttaac ataagtgtgt tattctttgt atagataaaa gaaaggatac taatatggta
    19741 ttagcgatta ttttagtaac attctttatt cgattgattt ttttaaagcg ttcgatagag
    19801 aatgagaaac gaatccttag caatggcggg aaagaatttg gagttgagaa tacaaaacga
    19861 ttaactatgg ctcatattgt tttttatctc tcttgcttgg ttgaggcaat ggtgcacaag
    19921 acaatttttg atggcatggg tatggttggt ttagtcttgc ttattttttc tatgctgatg
    19981 ttaatgttgg tgattcactt gttgggagat atttggacag tgaagcttat gcttgtcaat
    20041 aatcacaaat atgtagatca tatcttgttt aggacagtaa aacatcctaa ttacttttta
    20101 aatattcttc ctgagttgat tggcttgacc ttgttgagtc atgcttatgt gacttttgtt
    20161 ttagtttttc cagtttatgc agttattttg tatcgacgaa tagctgaaga ggaaaagcta
    20221 ttacatgaag ttataatccc aaatggaagc ataaagagat aaatacaaaa ttcgatttat
    20281 atacagttca tattgaagtg atatagtaag gttaaagaaa aaatatagaa ggaaataaac
    20341 atgtttgcat caaaaaacga aagaaaagta cattattcaa ttcgtaaatt tagtattgga
    20401 gtagctagtg tagctgttgc cagtcttttt atgggaagtg tggttcatgc gacagagaac
    20461 gagggaacta cccaagtagc cacttcttct aataaggcaa ataaaagtca gacagaacat
    20521 atgaaagctg ctaaacaagt cgatgaatat ataaaaaaaa tgctccaatt agatagaaga
    20581 aaacataccc aaaatgtcgg cttactcaca aagttgggcg caattaaaac ggagtatttg
    20641 catggattaa gtgtttcaaa agagaagtcg gaagctgagt tgccgtcaaa aataaaagca
    20701 gagttagacg cagcttttga gaactttaaa aaagatacat tgaaaccagg agaaaaggta
    20761 gcagaagcta agaagaaggt tgaagaagcg gagcttgaac tagtaaaaga ggaagctaag
    20821 gaacctcgag acgaggaaaa aattaagcaa gcaaaagaga aagttgagag taaaaaagct
    20881 gaggctacaa ggctagaaaa catcaagaca gatcgtaaaa aagcagaaga agaagctaaa
    20941 cgaaaagcag atgctaagtt gaaggaagct aatgtagcga cttcagatca aggtaaccca
    21001 aaggggcggg gaaaacgagg agttcctgga gagctagcaa cacctgataa aaaagaaaat
    21061 gatgcgaagt cttcagattc tagcgtaggt gaagaaactc ttccaagctc atccctgaaa
    21121 tcaggaaaaa aggtaacaga agctgagaag aaggttgaag aagctgagaa aaaagccaag
    21181 gatcaaaaag aagaagatcg ccgtaactac ccaaccaata cttacaaaac gcttgacctt
    21241 gaaattgctg agtccgatgt gaaagttaaa gaagcggagc ttgaactagt aaaagaggaa
    21301 gctaaggaac ctcgagacga ggaaaaaatt aagcaagcaa aagagaaagt tgagagtaaa
    21361 aaagctgagg ctacaaggtt agaaaaaatc aagacagatc gtaaaaaagc agaagaagct
    21421 aaacgaaaag cagcagaaga agataaagtt aaagaaaaac cagctgaaca accacaacca
    21481 gcgccggctc ctcaaccaga aaaaccagct ccaaaaccag agaagccagc tgaacaacca
    21541 aaagcagaaa aaacagatga tcaacaagct gaagaagact atgctcgtag atcagaagaa
    21601 gaatataatc gcttgactca acagcaaccg ccaaaaactg aaaaaccagc acaaccatct
    21661 actccaaaaa caggctggaa acaagaaaac ggtatgtggt acttctacaa tactgatggt
    21721 tcaatggc
//
LOCUS       DAVHSL010000033        21548 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000033 DAVHSL010000000
VERSION     DAVHSL010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21548
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.034"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(67..615)
                     /locus_tag="VVR39_001348"
     CDS             complement(67..615)
                     /locus_tag="VVR39_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU6030833.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(630..1478)
                     /locus_tag="VVR39_001349"
     CDS             complement(630..1478)
                     /locus_tag="VVR39_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU6030834.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            1667..3016
                     /gene="trkA"
                     /locus_tag="VVR39_001350"
     CDS             1667..3016
                     /gene="trkA"
                     /locus_tag="VVR39_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU6030835.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            3020..4459
                     /locus_tag="VVR39_001351"
     CDS             3020..4459
                     /locus_tag="VVR39_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6030836.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(4585..6264)
                     /locus_tag="VVR39_001352"
     CDS             complement(4585..6264)
                     /locus_tag="VVR39_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6030837.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(6334..7746)
                     /gene="lacG"
                     /locus_tag="VVR39_001353"
     CDS             complement(6334..7746)
                     /gene="lacG"
                     /locus_tag="VVR39_001353"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6030838.1"
                     /translation="MENLQFKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(7756..8100)
                     /locus_tag="VVR39_001354"
     CDS             complement(7756..8100)
                     /locus_tag="VVR39_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6030839.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(8268..10154)
                     /locus_tag="VVR39_001355"
     CDS             complement(8268..10154)
                     /locus_tag="VVR39_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU6030840.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGHRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(10156..11478)
                     /locus_tag="VVR39_001356"
     CDS             complement(10156..11478)
                     /locus_tag="VVR39_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6030841.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            11647..12870
                     /locus_tag="VVR39_001357"
     CDS             11647..12870
                     /locus_tag="VVR39_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU6030842.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKDFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            13530..13700
                     /locus_tag="VVR39_001358"
     CDS             13530..13700
                     /locus_tag="VVR39_001358"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6030843.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEEAG"
     gene            14313..14597
                     /locus_tag="VVR39_001359"
     CDS             14313..14597
                     /locus_tag="VVR39_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030844.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            14590..15147
                     /locus_tag="VVR39_001360"
     CDS             14590..15147
                     /locus_tag="VVR39_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEU6030845.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(15514..17838)
                     /gene="pflB"
                     /locus_tag="VVR39_001361"
     CDS             complement(15514..17838)
                     /gene="pflB"
                     /locus_tag="VVR39_001361"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU6030846.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYKKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            18232..19293
                     /gene="dinB"
                     /locus_tag="VVR39_001362"
     CDS             18232..19293
                     /gene="dinB"
                     /locus_tag="VVR39_001362"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU6030847.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(19440..20285)
                     /locus_tag="VVR39_001363"
     CDS             complement(19440..20285)
                     /locus_tag="VVR39_001363"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU6030848.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNRTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            20541..21409
                     /locus_tag="VVR39_001364"
                     /pseudo
     CDS             20541..21409
                     /locus_tag="VVR39_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6931 a         4418 c         3687 g         6512 t
ORIGIN      
        1 ctcaaaacac tgttttgagc aacctgcggc taacttccta gtttgctctt tgattttcat
       61 tgagtattag tcctttttca aacttcctgc acgagtttgg gttcctgcat aggcaagtaa
      121 gagaagagtt cctgcaatag ctacagatac accattggca attcccgcaa caatcccttg
      181 tgcaaatact ttttctgccg cttcttgata aatcacaaca tctccaagtg gtgccaagac
      241 accccaaaca agggcatttg caagtagttg aatgagatta aaaataagaa tatctttcca
      301 gtcaaaaaca ctattgatca cgcgaacgta ctttctaaaa agtcccacaa ctaaaccaaa
      361 gagtccgcta gcgataatcc aagtccacca tagaccataa ccaacaagag agtccttgat
      421 tgcatgacca atcaacccga caagcaaacc gataatcggt ccaaaaataa tagaaagtag
      481 cgcttgtacc gcatactgaa gctggatgct tgtatttgga acaggggttg gaatgttgat
      541 catcccgatg acgacaaaga gggcagcgcc aattccgaca gcaacaactt gtttaattgt
      601 aaatttgatt tccatactat tctcctattt tatccttcta ttttctttat ttcaatggtc
      661 caagatgaac cgacacctac attataggcc ttggcaaagg aaccttggtt gatagccaaa
      721 cctaaacgat agagagagtt gatgtaaagg atgggttgcc caattctcac atctgcaaat
      781 gatttgccat agacaacctg attttgatag accagcatat cagcatgata gatggtcact
      841 tcaaaacgat caccaaattc tggttccagc ttgtaaaatt cttcccgtgt gatagaggtc
      901 caaagcgaac cgaaacgcac atccagaata tcaatggctc ccttcaccag atgatcttct
      961 atgatggtcg ctacgactgg aagctctaca atctgttcca cactgagctc tggccctact
     1021 tcctcaaaag taatgtgacc actggccagt ttagcaccag tataggcata gacatcacga
     1081 ccgtggaagg tataagaatg ctctgtgttt tgacgcctat tggccacctc agaaatctca
     1141 cgaatggcta caatgccaac gtgtttcttg ataaaggaaa gcgtcccatt atctggcgtg
     1201 acaatgtatt gattttttgc agtcttggca actacactct tacgtttcga accgacacct
     1261 ggatcgacaa ccgatacaaa cgtcgttccc tcaggccagt aatccaccgt ctgaaagaga
     1321 cgatagctcc cctcaaaaat attataaggc gtgatatcgt gcgtcaagtg atggattttt
     1381 aaggttggag actcttctaa agccactcca atcatagccg ataccgcacc atcaaccaga
     1441 ccaaagtctg attgtaatac cagtaaatta ttattcattt tatctccttg tatatccttt
     1501 atcataccat atttcagaga aagtcgctaa tagctatttc aattggttag ggtatagttt
     1561 taacttatag caaatttcct actaaaagct cttgttatta gctagtaggt gcattttttc
     1621 ttgaaaaagg gtatgatagt tacatcatga aaaagtaggt tttattatga aaattatcct
     1681 tgtcggaggg ggaaaagttg gttttgccct ctgtcgctcc ttggttgcag aaaagcatga
     1741 tgttttgctg attgagcaag acgaagctgt tctcaatcat attgtcagtc gctttgatat
     1801 cattggtatc cttggtaacg gggccgattt tgccattctt gagcaagcca gcgtccaaga
     1861 ttgtgatatc tttatcgccc tgactgagca cgatgaagtc aacatgattg cagcagttct
     1921 agccaagaaa atgggagcta aagaaactat cgttcgggtg cggaaccctg aatattctaa
     1981 ctcttatttc aaggaaaaga atattctcgg tttttctctt atcgttaatc ctgagctctt
     2041 ggctgcccgc gctatcgcga atatcattga cttccccaac gccctgtctg tcgaacgctt
     2101 tgctggtgga cgcgttagcc tcatggaatt tgtcgtcaag tccaccagcg gtctttgcca
     2161 aatgcccatt tctgattttc gtaaaaaatt tggtaatgtc attgtctgtg cgatagagag
     2221 ggatcatcaa attatcattc caagcggtga catgactgta caggataaag atagaatctt
     2281 tgtcactggt aaccgtgtcg atatgatact cttccataat tattttaaat cacgcgccgt
     2341 gaagagcctt ctcatcgttg gggcaggtag aattgcctat tatctacttg gtattctcaa
     2401 agatagtcgt atcgatacaa aagtcattga aatcaatcct gaaatcgcca gcttctttag
     2461 cgagaaattc ccaaatctct acatcgttca aggagatgga accgcaaaag atatcctgct
     2521 ggaagaaagt gctcaacact atgatgccgt tgcgactcta acaggagtcg atgaggaaaa
     2581 tctgattaca tctatgttcc ttgacagggt aggtgtacag aaaaatatta ctaaggtcaa
     2641 tcgtaccagt ctcctcgaga ttatcaatgc gcctgatttt tcaagtatca tcacacctaa
     2701 aagcatcgct gtagatacga ttatgcactt tattcgtggt cgagttaatg cccagtattc
     2761 agaccttcaa gccatgcacc atctagccaa tggccaaatc gaaaccctgc aattccatat
     2821 caaggaagcc aataaaatga ctgccaaacc tctttctcaa ctgaaattga aaaaagaggt
     2881 tcttattgca gccattattc gaaagggcaa gactattttc ccaactgggg aggatatgtt
     2941 ggaagttgga gacaagctcc tagtaacaac cttgttgcca aacatcacca agatttatga
     3001 cttgattgcg aggtaagaaa tgaataaaag tatgattcgt tacctccttt caaagttact
     3061 tttgattgaa gctgttctcc tcttggttcc tgtggctatc gctgtctatt accgtgaatc
     3121 gagccaagtc tttacagccc tcttttcgac catagggatt ctcgtattgt taggcggttc
     3181 agggagttta cagaagccaa aaaatcaacg gatttatgcc aaggagggag tcttgatcgt
     3241 tgccctctgt tggatccttt ggtctttctt tggtggtctc ccctttgtct tttctgggca
     3301 aatccccagc cttattgatg ccttttttga aattagttct gggtttacaa ctactggagc
     3361 aagtattttg aacgacgttt cggttctcag ccgttccctc ctcttctggc gaagttttac
     3421 ccacttgatt ggagggatgg gagtgcttgt ttttgcactt gctattatgg acaatgccaa
     3481 aaatagccac ctagaggtga tgaaggctga ggttccaggt cctgtttttg gcaaggttgt
     3541 atccaaacta aaaaacactg cccagattct ctatctcctt tatctagctc tcttctccct
     3601 ctttgtcatc atctattatc tagctggtat gcctctctac gatagttttg tcattgctat
     3661 ggggacagcg ggaactggag gctttaccgt ctataacgac ggaattgccc actatggcag
     3721 ctcactgatt acctatctgg tcagtatcgg agttctggtt tttggggtaa atttcaacct
     3781 ctactactac ctcatgctcc gtcgcatcaa ggccttcttt ggtgacgaag aacttcgggc
     3841 ttacttggtc attgtactgg tttctacagg cttgattagc ctcaacaccc tctacctcta
     3901 cccagggttt tcaaagagct ttgaaatgac cttcttccag gtttccaaca tcattacaac
     3961 aactggtttt ggatatggag atattaccaa ctggcccctc ttctcccagt ttatcctcct
     4021 tttcctcatg gcaatcggtg gctctgctgg atcaactgca ggtggactca agattattcg
     4081 aggcctcatc ctttcaaaaa ttgccaaaaa ccaaattttg tcaatcctat cgccccaccg
     4141 tgttttgacc ctccatgtga atcaaacggt gattgataaa gatacccagc ataagattct
     4201 caagtacttt gtcatctatg ctatgatttt gctagcgctt atctttattg tcagcctaga
     4261 tagcaatgat tttctggtcg tgaccagcgc tgtctttagc tgtttcaata atatcgggcc
     4321 tattctagga accacttcta gtttctcaat ctttagtccc atctcaaaaa ttctcctatc
     4381 ctttgcaatg attgcagggc gcttggagat ttacccaatc ctccttctct ttatgaagag
     4441 aacttggtct aagagataaa atacaaaatc cctcttttta caattgtgaa agagggattc
     4501 ttatattaaa aaagggggaa cgtttttaaa tccaagccta tctgtaagca aaatccttac
     4561 tcaaataaaa gatggaaaaa cttactacac agcttggtaa tgctccaata caaattgtaa
     4621 ggatttactt ggactctttg ttaaatgaat atattccatt cctctggtag caactatctg
     4681 aatacctaat ctttctgcat ccaccttcat ctctctataa taactccgaa cttgtggagc
     4741 cagaataatt aaatcataaa cacccataat atcataatga gctccgtacg ctcctgaatt
     4801 cgcaatcact ctaacttctg ctaattgagc gccctcgtta attgcattgg ctaattgcgc
     4861 acttgttcca gaccctgcac aaagaaccag tactttcaac tccttacttt ttatttcatc
     4921 taactcacca ggcattattt cacttgtctc ctcctctaaa ataatatcat ttgagcttgc
     4981 aacatcttct ttcatcagta actgtctatc atacgctcta cagaatggca aataaatcaa
     5041 tatgtcgaca actaaaatca aagataaaaa tacaaaggag atagattgaa aattcgttcc
     5101 aattaacaat cccaagggac caggaaaggc ccaaggtaac tggatataaa atccattcat
     5161 tccaaagaaa tcaataaaga cctttcctag aaatacattc actggtggag tcatcaaaaa
     5221 aggtacaaaa agatagggat tcaaaataac tggcatacca aatagaagag gttcattcac
     5281 cgcaaataaa acaggagtaa ttgtagcttt acctaccgat tttaattgtt tagaccgcat
     5341 aaagaaaatc aaaataaatg gtacaacaaa ggtagccccc gttcctccga tagcagcgat
     5401 ataatttccg aaattaggcg ttaaagaatg ataaggaaac tgcccatttg caagaagttg
     5461 agcattctct tccatattgc tcagttgtaa agctgtaaca gcaggtaaga caatagatgg
     5521 tccatgaatt ccaacaaacc aaagcaaagc gcacataaac caaatcaaca tcatagcagg
     5581 atatgattct gcccccttaa aaataggagt caatagttgt tgaaatactt gggcaaaagg
     5641 aacatctaaa ctaaaccgag atacaatatc taacaaacca ctaataagta aaacaaaaga
     5701 aaaaggaaaa atatctctaa aagcttgtga tatagcccca ggaacttcct taggtaaatg
     5761 aatagtaatg tctcgcttaa tacagaatcg gtaaacattt acagtaataa aggcactgac
     5821 aaacgaagtt atcaatcctt gagatcctaa atagtttgtc gacaaacttg tagatcccgt
     5881 tttctcatca actacaagcg ttacagttaa tacaagatag ccacatatgg ccgccaacat
     5941 tgcagaagta tcatttatta cctttccagg aggcattttt ctattaacat ttccagccaa
     6001 tgactttgca actgtccctg aaacaataac acccaaaact cccatggtta gcatatacac
     6061 tttcctcatc caggcaatag ctggactcgg taactctact ccgaaatttt taggaatcat
     6121 aataataatc atcaaaaagc ttgaaaacat aattaaaggc atagtagcaa taaatccatc
     6181 tttaatagcc atcatataat tattagtaga aattttttca aatttccctt gttgcttttc
     6241 aatggcagcg actaacttat ccataaaaac tcctcctgta aaaaatttaa gctcatagtt
     6301 aaaatatatt aaacatcagt caaatcgcta accttaattc cgttttaatc cttttaccca
     6361 aagagcactt ttcttaatat atctcttctg tgtttcataa tcaacaaaga aaagaccata
     6421 tcgcttattg tagccattcg cccaagaaaa ttgatcttgc aaagaccata taaaatagcc
     6481 ttgaatattg actcccctat ctcgagcctc taaaactttg tgtaaatgtt gctcaatata
     6541 acggattctt ttactgtcat caataatatc attctcgccc tctggcttaa cctctttaag
     6601 ggctgtacca ttttcagtta aataaatgac cggatgttga ggatattctt ctttgatacg
     6661 aagcaacata tcaaataacc cttgaggata aatattccaa tcccaatctg ttgtcggaat
     6721 accaggcttt tttacaaatt cacctagagc atttaattta aaagaagact gtccttttat
     6781 tcctgttgaa ttaaattctt gtctattttc acctttgtat tcacgaataa attctgaacg
     6841 ataataattc atcccaaaca tcgtattaag aggtgcagct cttttcataa tttctaaatc
     6901 accatcttca ataataaagc tagaattatt agcttccaat atttgattca agtgaaaaag
     6961 cgtgtcatca ctgtagtagc ccaaaaaagt tccatctaat agaaatttat tattataaac
     7021 atcataccgt ttagctgcta aaatattttc tttttgccca tcaataggat agcctggctt
     7081 taaagcatga atacaaccta tctctccctc aattcctaat tgatgaaatt cgaggactgc
     7141 aagagcatgc gccaacaaca tattatgatt cgcttgaatt gcttcagata attgaaaatg
     7201 atgatttgga ggaaactgac ctcctatata ttgacctgca gcaagagaca tcagttcatt
     7261 gattgtaaac caatgcttga cttctgtaaa ttcttggaaa caaaagcgag catatcgtat
     7321 gaaacgatca atattctctc tattcaacca atcccctgtt tctaacattt tctgaggcga
     7381 atcaaaatga tgtaaagaaa caaacggaat cacattatgt tttaagcaag actgaaagac
     7441 tctatggtaa taacgaacag ctaatatatt cggctcccca tctatatcag gaaatatacg
     7501 aacccaagaa atagataaac gcaaagcctg caaaccatgt tctgccgcca aagctatatc
     7561 ctcttcgtaa cgataataaa aatcactagc tggatctggt aagaacggac tattttcttg
     7621 caaataaaca tcccacatat ttattccttt gccatctacc ctagttgcac cctctacttg
     7681 ataagcagcg gtagcagctc ctaataaaaa ctccttcggt aaggctttaa actgtaaatt
     7741 ttccatgact aatcctcatt gcaaaccaat atgttcttca atctttcgaa ttcgttcata
     7801 ttcatcaata aaaaacttta cctgatcata caatagcatc gttgtcatca aagtatcttg
     7861 accatgaatc ataataaagc tcacttcaaa attatctcca tatgcctcct ccgctaataa
     7921 attagtctgt tctcgatggg cagacactat tgagtcgttt gcagactcaa ccaattctct
     7981 tgcctgttca aaatatccat ctctcgcaaa cgccaaagca tccatcaaat ctgaccttgc
     8041 atctcctgcg taagcgacaa ttgtaaaacc aagcatattt atttcttctt ttgatttcat
     8101 ctttcttcct cctcaatctt gatccatctt ttacacatca ttattaaaat gacttcgcta
     8161 cgatataaat agaaagtcga ccctaaatat cttaaaaatc cttaaatttc ataatattta
     8221 ggatcaatct tctctgaata ccttggttca ttttctatac ttatgattta taagtggaaa
     8281 ccagcgtaat tttttgctac ttcaattaca cgataaacat ccaaattaga ttggaatagc
     8341 agttcgtgcc cacggatata attcaacaca tttctccatt catcttgagc ttgccttgtt
     8401 tttccggttg cttgaagata taaagccttc gccatcttaa caacatattc acgatgataa
     8461 ctgagctgtt tccattcatc cttttgacta tttaataact tagaaatatt ttcctcaata
     8521 attggcaaaa aattatcagc tagattgtaa gctatataat aatgattcgc taaaacatca
     8581 ttttgacgac tgccaattgc attaaaataa tcacatgagg aataactgga taatttttct
     8641 aaatattcaa caacagactg ccaatttgac ccatacaaag cagaaaagta ttcttcaatc
     8701 aattcttcat aacttcttgt cttcttccag agcatttccc ccataacata attaggaaaa
     8761 ttatgaggga atccggcacg taattcttga cacgaaatgt aaccgttcaa atgtaggtta
     8821 gaaagataag atacatctct gtaaatggtt tgactaattt tcatatagcc taaatcgcca
     8881 taatgagcac gccctaaagg atagtcatat acgaaactat ctcctttaaa tgttttttgc
     8941 cactcaaaaa gataagataa attttcctca agagaattcg gaagtataat tttattacgc
     9001 agataaggtt taggcgtagg tatggaattg tcaaaatcta catctgcata actcatttca
     9061 aatgttcttg taatcggtgc aaacatcatg gtaaagcgtt caggattatc taatttttct
     9121 ttctgaggcg cccatagcaa ctcatggtaa agcagaaaac aaatctttgt atctaatccc
     9181 tcactcgtta aagccctatc caattgattg agaatacgaa tatactgatc cgaaaccaat
     9241 tcttgtctac agttttcgca ttcacaaata ttattacgag catccgacaa ccatacatgt
     9301 aagtagttaa catcaggtct tttcttggca taatccttga taatttctac catcttatcc
     9361 gccacatctg gatttgaaaa atccagactg gttaaaatcg gagccgtatt aaataattct
     9421 cgtttcccgt ttatttcagc gacatacggt ttcttctcct ctgaaatact aagacctgat
     9481 tcccagccaa attttgaaga gtaacctaaa acctcacctg tccatccatg accaacacga
     9541 tgatgaataa gacctctttt ttgcaattct ttatccaacc tatcactcaa ttcttgtact
     9601 aattcatttg agaatttttc tttatttagg tatggattaa actcatgttc ataccaacgt
     9661 ttcaaaaaag agtagggatt ttcaaactgg atgaaaaaac tgttcatccc aatcttaggt
     9721 agccaatcaa tgaaatctag tatattttca aatgaatccg ctccctctat acatactccc
     9781 ctatgatagt aactggctgt ttcatctata gatagctgtt tatctaaaaa atcttcaaat
     9841 cgtaactctg gaacaaagtc atgtctgtgc cctggtctag tatacacaac cccaaattca
     9901 tgaaacattc ggtaaattcc aataagtaaa cctacaattg tattagactc aattctcccc
     9961 ttacccttgt ctaatgagat aagaacatgg tctcttctat cctctttatt gactaatcct
    10021 acaaaaatat ccgcttcctt ctcctcgaca agttctatgt cagtcttaaa gacccgattt
    10081 atatagtaac ttaattcctc taaggcaaag ctagaataag tatttttctg cttatcaaat
    10141 actctgataa ccatcttatt tccctccaac agtagctttt tctttttcaa gattgcgttt
    10201 atctgcaatt ttgaagaatg gataataaat tgctacagaa accaaaatca aaacaacttg
    10261 taatagagct cctcgccaac tagctcctgt cgcaaggaag cctcctatga tcggtggcat
    10321 tgtccacgga aggattacac ctgttgtata gggtactaat cctacagcca ttgatacata
    10381 ggtaattaag gcattgattg taggagtagc aataaacgga atcagcataa tcggatttaa
    10441 aactgttgga aacgtaaata gaatagctgt attgatatta aaaatagacg gtataatagc
    10501 tagcttacct aatgttttat tcgcacgact cttactaaat aggaagagac aaatcgcaag
    10561 accaatagtc gctccaccgc caccaataaa tacaaataaa tctttaaacg gtaatgtaat
    10621 aatgtgttgg agtgtttgtc ctgcagccac agcttcttgg ttttctgtag taaattgtaa
    10681 ccaaactgga tctacaaaag catttaaaac ttgtccccca ttaactccac agaaccaaaa
    10741 gaatgagttt acaataacac atagaatcat acctggaagc gttcctgcaa ttaacttaag
    10801 cggtgttcca acaattgcac ctaggagtcc gttgagacct cctgcaactc ctgccgcttc
    10861 aagacctttt aagaccagag cccacaaaac aaaagtagta aagccaggta aaagagctga
    10921 aaatgattta cttaccacat ctgggacacc acttggcatt tttatcgtaa ttccgcgctg
    10981 gataaacata cgataaatct ctgctgtaac caatccaata gtaatcgcca taaacaaaga
    11041 agatgcattc aggctagaaa atggtattgc gccgccaaat aactgcttga cctgctcccc
    11101 atttttatca taaaccatac tcgaaaaacg aggtgccatc aatacaaaac tggataaggc
    11161 tatgatccct gccgacggac catctgtacc atatccttcc gacaacctgt aggcaatacc
    11221 gaaacaagcg accaaggaga taatcgctac tgttgactga ttcatagttg tcaagatact
    11281 tagcaatcca acactattca gccaatttgt aaaatcctct tgaggccaac tgattagaat
    11341 aagaaataaa gagccgacta aaatcaaagg cattgccatc ataaatcctt cacgaatagc
    11401 tttcaaatgc cgttggttgc caactttttc accaaacgga gcgacttttg tttctaaaaa
    11461 cgttaaaata ttgttcatca ccggaactcc tttttttatt ttttataaat taaatatacc
    11521 actaatagaa agcgttgtca atatattttt ttgctgtttt tacaatattt ttttctttgt
    11581 atagaataat aattttaatt gattttttct tatgtttaat ataaaataaa ccaaaggagg
    11641 aaacaaatga ttacaaaaca atcagccttt ttacaaaata gagccactat actggagttt
    11701 ctatatcgaa atccagcaac atctcgtaca gatattgtta atgaaacagg acttactcca
    11761 gcaacaacga ctaacatcat caaagagcta agtgaacagt ccctcatata cgaaactggt
    11821 gatgaattta gcgagttttc cggatctgga agacgtagaa aaactatttc tattacagat
    11881 aatatcccat atgttgttgg aggtattgaa ataaacgtcc taggtatctt tctcagtcta
    11941 tgtgacttac aagggaaaac tcttttcgag acagaaattt tgaatgaaga ttatcctatt
    12001 tcagaaatca attccaccat taccaatatg ataaaaacag ctatagagta tgtccctttg
    12061 gagacaaaat tacttggatt tggcttatca atacctggac attataacaa agactccgga
    12121 agcatcatta caaacaaccc catatgggaa tcttttaatt tattaaatgt aattaaagat
    12181 ttcaattttc cttttattgt aaaaaataat atcgattgta tggctatagg acaatacctt
    12241 tttaatccac acaatacccc cgataacttt attttcctac acgctggatt aggtatttac
    12301 acttcctttt tcacaaaaga aaaaatagga gcctctaaaa atccttatat cggagaaatt
    12361 ggacacacca ttgtcgaatt gaatgggcaa tattgtgaat gcggaaaaaa aggttgttta
    12421 caaacatata tttcggatgc ttggttaatc aaacacgccc aattattatt taaaaattcc
    12481 caactaactg tactaaaaag ccttgtaaag actgaaaaag acattcattt agacaccctt
    12541 ttaacggctt ataatttagg cgactccgct ttacgccaac aaattgataa aggagtcaat
    12601 ttattggcca cttctattgc aaatcttctc ctcatcaatc ctgctgataa aatctatatc
    12661 aacagtcaat tgcttaatta tcaacctttc actcatgaag tcagggataa aatccaagac
    12721 cagctccact tcgttccctt tactcgtaat atagaaattg aaattttacc ttacaacaaa
    12781 catcgtggaa gtataggagc ttgtgcatta gctatcgttg cttttttcat agagcatagc
    12841 aatgtattac aagatattat ttcaccttaa tatatattag aaatctatac acctgtttaa
    12901 atcaactata acctgtagta aatatctcgt atttagacaa tatgaaaaca agacgacttc
    12961 catataggaa accgccttct ctctatgttg agtgatttat attaaaataa cttttcttct
    13021 agctgcattt tattattata aaaacattca tcataacccc cagaacttaa ataacaattt
    13081 ttattcaaga tacatactcc tagaataaac tttatatgaa atccccattt ttgtttttac
    13141 aattctcctt agttaaatct tgtttaatat atgttttaca tatagtattt agcgccacat
    13201 agtactgaac tctctccaaa aacggttatt cctctttgaa tagggcgtta tcacaagaaa
    13261 agcatctcca cgtttcaact tcatatggct caaaaacaat taattgatgc taaaacctgt
    13321 acctagatgt ttcggttcat aaaaccatga aactgtaaaa gtggatgaaa ttgatagtga
    13381 tagtcaaatc aagaggcatc ataactctaa aaagtcacaa tatataagtt catcctcgga
    13441 aaaatatcat tctaattgtt gaaatggata tataaacagg ggtattaaca ttaaatgctc
    13501 atgaaacaac gaatacaggt atcaaaacta tgacaaaaca agtccctaaa tttactaaag
    13561 acactgctca actttacacc tgtaaatggt tgttgtataa taaagttaca aagatgtacg
    13621 accacactgt tgtaaatcat agtgttcgcg aatatattac tgatagcatt tctacaaata
    13681 caattgaaga ggctggatag gctttaaacg aaatatgtca gtgttttggc attcctagcc
    13741 ttaatatcat ttaaagaatt gtatagataa aattttttcc aatacagaca ctcgtaacaa
    13801 ctgcttcatt tttctaccaa catatttagg aacaggataa gatacaagag gattaatcca
    13861 taaatcagtt ctataccaat ctaagacaaa taagctaaaa aaaacgattg ataataagca
    13921 aatagattcc aaattttctc tatcggctca ttttaataaa caatactagt gtaactatcc
    13981 ttccagtcag aaacttgtca aatcacaccg aaaattcttc taaaatttat ctcgttaggc
    14041 aatcaagcaa aaactcgacg atagtacaaa cattatcata caggattgac ttcctaaatt
    14101 atatacttta gtaaggtttt cggataagaa aaaaggttca ttttacattt ctaaacattc
    14161 ttttctaaga tgaaaaacag aatttttcga ttgtgattta aagcaacaag aagattttca
    14221 gtatcatcct atagatccga gctaattaag aaaaactaca tttttgaata taaactacaa
    14281 taatataaac taaatttcat aggaggaaga caatggattg gtacgattat atgatacagg
    14341 catccaaaca atcacaattc aacgcaagcc attggtttcg ctatttgcga aaagttattt
    14401 ttgaagacta ttcttattta acaaaccaag atgtagaaaa gttgctagac tccaaagaac
    14461 taacccgttt tcaaaaaatt agcttgaagt atgcctttca agagcatact ccaactcata
    14521 aatatgtgat ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa ttgatggaga
    14581 aatacaaaca tggataaaat gaaaccggtc ttccaagccc taaataagga attaattcag
    14641 gaaaatctga ctttaacaat tatctgtgtc gatggttatg tcttagaata tcatggttta
    14701 cgtgccacac aagatgttga tgctttttat gaccaaaatc agaaaatcaa tgaaattatt
    14761 gctcgtgtag gaaaacagtt taatcttaac acccacgaag agttatggct caacaatcat
    14821 gttgcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta ctcatttgag
    14881 aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat gatgagtatc
    14941 agagagcagg atttgaaaga tattggtgca attattaaat acaaaaactt tcattcacca
    15001 ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct ctctgttcta
    15061 ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt taaagaaaat
    15121 caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc aattagccag
    15181 tcgtcttatt tttatgatgg aatgaaataa aatcggaaca aatcacttag agaattccag
    15241 tcaatttcta gcactgtttg agacgtttca gcggactata gtaaaatgaa ataagaatag
    15301 gacaaatcga tcaggacagt caaatcgatt tctaagaatg ttttagaagt aaaggtgtac
    15361 tattctagtt tcaatctatt atatttcaga ttcggtccac tattccttcc caaaaacatt
    15421 gcatattgcg ccgaaggaat tgctcacact atcccaagca caaaaccctc agtcgattga
    15481 ccgagggttc ctttttatta ttcaagaact tgattagctc aatgcatcca aggcatcatc
    15541 cattgaaaga acttcgtgga agacacgttg tgtcaattca gttttttgtt ctggagtgag
    15601 gtatttagtg tttacacagt atccagagat acgtacgata acgtcttcgc ctgacatgat
    15661 ctttttgtaa acatcgttca agtccataac gttcaagtta acgtgttgtc caccgttttc
    15721 aaagtaacca tcaaggattg ttaccaagtt atcaacttgt tcatcacgag tcttaccaag
    15781 agcgcgaggt gatacttgtg tagtcaatga gataccgtca gctgcataac taaagtcaag
    15841 gctagaaagt gagttcaagt tttgcaacca accaccttta gctttgttag atgggttagc
    15901 acctggtgag aagaattcaa gtttagacaa gttcacagaa ccatcttcgt tgaggtatac
    15961 acctttgtga actggtgagt taccagtttg tttagagtaa gcaacgttag atgtgattgt
    16021 caaaagtgat actgtagctt ctgcgtcttt gtatagtttg tggctacgta gacgagttgt
    16081 gtaagcttcg atcaaccatt ctgccaattc gtttgaacgt gggtcatctt caccccagcg
    16141 tgggtagtca ccgattgttt cgtaatcgta gatgtagcca tcttcatcac ggattggttt
    16201 aactgtagcg tatttaatcg ctgacaatgt atcaacagtg ttagcaaatc cacaaatacc
    16261 gaatcccatg ttggcacgtt gtttagttgg caagaaggcc atttgaacag cttcgtagtt
    16321 gtacttatca gtcatgtagt ggatgatgtt caaggcatct acgtaagtgt cagtcaacca
    16381 gtcaagagat ttttcaaagt tcgctttaac tgattcgaat tcaagaactt cgtcacgaat
    16441 aggatcgatg tcaaatactt tgtagtcttt gtgaacatcg tcgtaaccac cattcaaacc
    16501 agtaagaagg gctttaagaa cgtttacacg agcaccgaag tactggatgt tgtggcgttg
    16561 ttcttcattt tctggatcaa gtggagacac acagcatgag atacagctca tttcaccata
    16621 tccgtcttta gccattgttg ttacaccttc gtattggata gaagagtgtt tgtggctcat
    16681 gtgcatacag tagcgacgga aattgtacgg caatttgtca gtccaaagaa ctgtcaagtt
    16741 tggctctgga gagttaccga tgttgtcaag agtgttcaag aaacggtagt ccatcttagt
    16801 aacacggtga cgaccgtcgt tacccatacc agccatagaa gttgtgatga atgttgggtc
    16861 acctgagtac aattggtcat aagcttttgt acgagcaaat ttaactgtac gaagtttcat
    16921 aacgaaatca tcaacgaatt cttggatttc tgattcagta aatgtaccac gagcaaggtc
    16981 acgttctgca aagatgtcca atacgattgg tacacgacct agagatgtag cagcaccgtt
    17041 aatcacacgg cagacagcca tgaaagcaat gttaacccat tggattgctt ctttcacgtt
    17101 catcgctggt ttgcgaacat caaccccgta aaggtcaccc aggcgaacaa cttgttgcaa
    17161 tgcttggtat tgaaggttta cttcttcacg aagacggatt gtttcttcat cgatttcttt
    17221 gattgcattc cagtcattta ctttttcttg catcaagtag tctgcaccgt aaagagcaag
    17281 acgtgcgtaa acaccgatga tacgtccgcg tgagtatgca tctggaagac cagttacagt
    17341 gtgtgcgtga cgagcgcgac gaatatttga agtgtaggca cggaaaatac cgtcgttaac
    17401 tgttgttaca tatttagtga agatttcgtg aacagctggg tctggttcgt atccattttc
    17461 ttttaaagta gtttcagcca tacggatacc accttttggc atgaagttca atttgaagag
    17521 ttcatcgttt tggataccga agataacttc attttctttg tcgataaatc cagcagggat
    17581 atcagcgata gatgttggac gagtgtccat tgggaaacga gtttcttcgt agtgtgcttt
    17641 agtttcttct acaattttct tgatgtgaag tgaacgctct gttggtcctg caaggaagct
    17701 ttcgtctcca tcataaggtg tgtagttagc ttgtacaaag cgtgatacac ttgctttttc
    17761 tttccaatct acgcctttga agccttccca agctttgtca aaaatatctt gtgcttcaac
    17821 aactgtctta acaaccatat taatgtcctc ttttttctag taacagtcat ctgttacatt
    17881 cataagacaa gtataccata aagtaaccga tttcaacaag tgcaaaatcc ctatttttac
    17941 actttctttt ctaaaacagt ctatatttta tttcaaactg tattatattt ttgaaaaaat
    18001 aaagtccttt tttctttttt tcagaaaaaa gggtataata aaagaaaata agcagtaaca
    18061 ctcaatggaa atcgaaaagc aaactaggaa gctagccgca ggctgctcaa agcactgctt
    18121 tgaggttgta aatagaactg acgaagtcag ctcaaaatac tgttttgagg ttgcagatgg
    18181 aagctgacgt ggtttgaaga gattttcgaa aagtataaaa aggtgctagg catgttgatt
    18241 tttcctttgc taaatgattt gtcaagaaaa atcatccata ttgacatgga tgcctttttt
    18301 gctgcggtgg aaatcaagga taatcctaaa ctcagaggaa aacctgtcat tattggaagc
    18361 gaccctcggc aaacaggtgg acggggagtc gtttctacct gtagctatga ggctcgagct
    18421 tttggtgtcc attctgccat gagttccaag gaagcttatg aacgttgtcc ccaggccgtc
    18481 tttatctcag ggaattatga gaaatacaaa gctgtgggac tccagattcg agctattttt
    18541 aagcgctata cagatttgat tgaacccatg agcattgacg aagcctattt ggatgtgaca
    18601 gaaaataaac tcggtatcaa gtcagcggtc aaaattgctc gcctcattca aaaagatatc
    18661 tggcaagaac tccatctaac tgcttccgca ggcgtttctt acaacaaatt cttagctaaa
    18721 atggcgagtg attatcaaaa accacatggt ttgacagtga ttctacctga acaggctgag
    18781 gattttctca aacaaatgga tatttccaaa tttcatggag taggaaaaaa gacagtagaa
    18841 cgtcttcatc aaatgggcgt ttttactggt gctgatttac ttgaagttcc tgaggtgacc
    18901 ctaatagacc gttttggtag actaggctat gatctgtatc gaaaggctcg tggcattcac
    18961 aactctccag tcaaatccaa tcgcatccgt aaatcaatcg gcaaggagaa aacctacggg
    19021 aagattctcc gtgctgagga agatatcaaa aaagagctga ctcttctatc agaaaaagtc
    19081 gctctcaatc tacatcaaca agaaaaagct ggaaaaattg tcattttgaa aatccgctac
    19141 gaggactttt caactcttac caaacgaaaa agtcttgctc aaaaaacaca agatgctagt
    19201 cagataagcc aaatagccct gcaactctat gaagaattaa gcgagaaaga aagaggtgtc
    19261 cgcctattgg ggattaccct gactggattt taaagctcaa tgaaaatcaa agagcaaact
    19321 aggaagctag ccgcaggctg ctcaaaacac tgttttgagg ttgcagataa agctgacgcg
    19381 gtttgaagag attttctaag agtataaaac cttgaagagt tgccccttca aggtttttct
    19441 tatacaaata aacggacaaa actgtaaagt agcaaaacac taccaagcac gatacggtat
    19501 ttaccaaaaa gggtgaagtc gtgttttttc acatagctgg tcaagaagcg aatagccacc
    19561 atgctgaccg caaaagctac tcccatcgcg accaagagca aaaacaattg cccaaagctc
    19621 aagagttctc ctgcttttac aaatttgaaa atctttaagg cactagctcc aaacataacg
    19681 ggaatcccaa gatagaaggt aaattctgtc acaactgaac gactggttct atttaacaaa
    19741 ccaccgacaa tcgttgcacc tgaacggcta gtccctggta aaagagcaag aacttggaag
    19801 agtccaatat agaaagcggt cgtataagga agcttgtcca actctgttac acttggctcg
    19861 atagcacgcg ctttattgcg cttttccaaa tagatgaagg caaccccgta gataatcaac
    19921 atgagagcaa ctgaaaccat gttatggaag tgggtatcaa accaatcatc aaatttaaag
    19981 acaccaagta aaggtaaagt agcaatcaag accttcaacc atagtctcca agtcttacga
    20041 acttcctgtt tgtccttagt cggtttaaaa ggattgagct tgttaaaata aatcaccata
    20101 actgctaaaa tagcaccaag ctgaatcacg acattaaaca tggacataaa ggcttcattt
    20161 tgattttggt attggataaa ctcctctgct aaaatcaagt gacctgtact ggaaatcggc
    20221 aaccattccg taattccttc aacaatcccg aagaagatag attttaaaat ttcaataaga
    20281 tacatagatt tctccttata ttatatttaa cgcagttagc tactgccaaa gcccaagtgg
    20341 tatacttgga ataagccact gtggattagt tcatttcctc caatcgcttg acgatttccg
    20401 aaagggtcta accacagctt tttgtttcaa ttggtaatga gtttgataac gcatagacgt
    20461 tttatctcgt ctaaggtaac aaggcaaaaa gttcgtggat aaccaagtag acttgaaata
    20521 ctatatctgg aggtactccc atgctttatg tgggcattga tgtcgctaaa aataaacacg
    20581 atgttacagc cttgaatgtt cgaggaaaac tgttcttaaa ccactcactt tttcaaataa
    20641 taaagctggt tttgaactct tagatctgtc ttttcgacag ctcaaccaag actgtctcat
    20701 cgctcttaaa cttctttctg accccaatcg tgaacaattt caacacgata atcggcaagt
    20761 agaactaaaa atactggcta gacatattca tcgtctcaag aaaaaacagt ctgattggaa
    20821 agtacaatac actcgttgtc ttgatatcat ctttcctgag ttggataaaa tcgttggaaa
    20881 gcattcagaa tatacctacc aactcttgac acgctaccct aatcctcaga aaaggcttga
    20941 ggcaggattt gataagctga tagaaattaa gcgattgacc gcttctaaaa ttcaggatat
    21001 cctctcagtc gcacctcgtt ctatcggaac aacatctcct gctcgtgaat tcgaaatcat
    21061 cgaaatcatc aaacattaca agaggctcat tgacaaggcg gaaacatgtg tcaatgactt
    21121 gatggctgag ttcaactcgg tcatcacgac ggttactggg attgggggtc gtttaggggc
    21181 ggtcatttta gccgagattc gaaatattca tgcctttgat aatcctgctc aattacaagc
    21241 tttcgctgga ctggattctt ctatttatca gtcaggtcag attgatttag ctggaagaat
    21301 ggtcaaacgg ggttcccctc atctgcggtg ggcactcata caagctgcca aagcatgcgc
    21361 tcgcttttca cctgctttta aggcctatct taagactaag ttagaataag gaaaacatta
    21421 caatgtagcc atcatccacc ttgcaaaaaa acttatccga accctgtttt atatcctaaa
    21481 aaagagctgc catttgacga acaaaaagtg atgtaatttc tgaaattaac acaggattac
    21541 ctttgaaa
//
LOCUS       DAVHSL010000034        21472 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000034 DAVHSL010000000
VERSION     DAVHSL010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.035"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(630..1094)
                     /locus_tag="VVR39_001365"
                     /pseudo
     CDS             complement(630..1094)
                     /locus_tag="VVR39_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091533.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
     gene            complement(1147..1656)
                     /locus_tag="VVR39_001366"
     CDS             complement(1147..1656)
                     /locus_tag="VVR39_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030849.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIDDVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            complement(1622..2185)
                     /locus_tag="VVR39_001367"
     CDS             complement(1622..2185)
                     /locus_tag="VVR39_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030850.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYKINGNS"
     gene            complement(2195..4183)
                     /gene="uvrB"
                     /locus_tag="VVR39_001368"
     CDS             complement(2195..4183)
                     /gene="uvrB"
                     /locus_tag="VVR39_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU6030851.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(4260..5213)
                     /locus_tag="VVR39_001369"
     CDS             complement(4260..5213)
                     /locus_tag="VVR39_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6030852.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLMDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLDQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVTMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            5385..7550
                     /locus_tag="VVR39_001370"
     CDS             5385..7550
                     /locus_tag="VVR39_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6030853.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            7550..8290
                     /locus_tag="VVR39_001371"
     CDS             7550..8290
                     /locus_tag="VVR39_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6030854.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            8439..9926
                     /locus_tag="VVR39_001372"
     CDS             8439..9926
                     /locus_tag="VVR39_001372"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU6030855.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDDKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGVPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(9970..11247)
                     /gene="ftsY"
                     /locus_tag="VVR39_001373"
     CDS             complement(9970..11247)
                     /gene="ftsY"
                     /locus_tag="VVR39_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU6030856.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVNPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11251..12069)
                     /locus_tag="VVR39_001374"
     CDS             complement(11251..12069)
                     /locus_tag="VVR39_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6030857.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(12069..12863)
                     /locus_tag="VVR39_001375"
     CDS             complement(12069..12863)
                     /locus_tag="VVR39_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6030858.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(12860..16399)
                     /gene="smc"
                     /locus_tag="VVR39_001376"
     CDS             complement(12860..16399)
                     /gene="smc"
                     /locus_tag="VVR39_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU6030859.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRSI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEVQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLDSEEVALKTLQDEMARLIESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEKELNRLSDGDWQADKEKCQERLATIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(16390..17088)
                     /locus_tag="VVR39_001377"
     CDS             complement(16390..17088)
                     /locus_tag="VVR39_001377"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU6030860.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(17271..17342)
                     /locus_tag="VVR39_001378"
     tRNA            complement(17271..17342)
                     /locus_tag="VVR39_001378"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17307..17309),aa:Arg,seq:ccg)
     gene            complement(17406..18392)
                     /locus_tag="VVR39_001379"
     CDS             complement(17406..18392)
                     /locus_tag="VVR39_001379"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU6030861.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(18567..19883)
                     /locus_tag="VVR39_001380"
     CDS             complement(18567..19883)
                     /locus_tag="VVR39_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU6030862.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(19870..>21472)
                     /locus_tag="VVR39_001381"
     CDS             complement(19870..>21472)
                     /locus_tag="VVR39_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU6030863.1"
                     /translation="ISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGR
                     SAMVTKLLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPE
                     LEPSKVGTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKT
                     YLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDF
                     CQKAKETQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGV
                     PGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFV
                     FIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGT
                     MNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLGKELNIHAEEAKIRLRNLNAAIENV
                     QELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFE
                     LTNNEQKDQAVADDNEGDENDDADY"
BASE COUNT         6287 a         4754 c         3814 g         6617 t
ORIGIN      
        1 taatataaat ttcggaaaaa tatcagaaaa tctattaaga ttgaacaaat ttcagatatt
       61 ttcacctcca ctctgtgtat tgcttgtttt tcactattgt gaacatatta attcaaaata
      121 tatctgggta atagaattat gttttaatta aaaacaaatc ccttcctaca aatatatctc
      181 tgaagacacc tgcaactaat cctgtaatct tggcaagata aataaaaaaa caaggcgtac
      241 tccaaactac cgataccttt taacgatagc cttagaataa gccataattt ctacacttta
      301 tttacttagt tggtacaact tttgacatca atactaccgt ctcaacatgt gccgatagta
      361 agctcctgta ctatcgaaca ataggaacat actaggattt attattatat tattgaacga
      421 aaacataaag agtaacataa tcgtacctct cctactgtct ctttgtcatt aagctactcc
      481 tagagctata gcctcatcac gaagacgttc gacatctacc acagtttgtt cccaactatt
      541 tgttgtatat tggttatata tggagtaatg gagtagagcg tttattaaaa caacaaagaa
      601 aggcgtactc atgtctatct tgtgaagggc tatctcaaag atgggaaagt tagatctgta
      661 cggcgagggt agaaaaactc tgacttgtcg ggagcttcca tcatttccat caatggtagc
      721 atatcatagg ccagattcaa gtttggaatc tggtcttttt gcacccaaga aacttctccc
      781 tcttctgaag attgaagggt accagagaac tcagtcgcct tataacaaat gacaatatag
      841 cgcccacctg tatctagtgg ccaattttta atgccgacaa gttgaggatt ttggatagtc
      901 aaccctgttt cttcatagat ttcacgaatg acagactctg cgaaagactc gccattttct
      961 acatgacctc caggaaaggc ataaccagac tagcgattgg ttgcaggaga gcgatactgc
     1021 atcaccacgc gctgcgtttc gaggtcttca atcagacaaa tggttgttaa aatcgttaat
     1081 tgggaacggg acataaattt actcgctttc taatttatta aattttcaga cttggtacca
     1141 gtgccattag cttctacttt ttaaaattat tttagaatag aataccattc gtttttcctt
     1201 tataggcttt ccaagttcaa gtatcttttc ttgtccatca aaagtaaaac ccattttttg
     1261 atagaaagca atggctcgct tgttatcttt caatacccat aagaaaattt cagaaaaatg
     1321 attcagagca gtcaaagctg ctttcattaa cttttgtgct atgccttttc cgtaatagtc
     1381 ttttaaaaca tataaagcaa taatttcacc agcttgaata gtctcatcac gaaagtttcc
     1441 ataactgata aaaccaacta ccttcacgtc atctatcgca atcaatgtat tttctggata
     1501 cttttgacta aagaatcgac atctttctaa tgtcattgtc tcctgaaatt ctgcaggcaa
     1561 aaggtcatca taagcctctc tccacgtttg ccagtgaacg agggatttac cttctatctc
     1621 ttcaggagtt tccattgatt ttataataac cgtcatttat tttctcccag tcttctctca
     1681 aaataccata tttaatacta tcaaaatatt taccttgata ataacgaact tttggaatat
     1741 gagcttcttt tttcattctt aatttttcag caagtttcat cataccaaga ttccctgacc
     1801 aagttgtcaa acccagatgc tccaactcca agtaatcctg aaacgtccta tctatccact
     1861 gcaacatagc aactttccca ataccagtgt tccagaattt tttatcataa ataccaattc
     1921 ccaattccat ccatcttgtt tgtttacata cccaataacg cgaaacagtc ccaactagtt
     1981 tatcatcaac aaaaatacca aggcgatttg agttgcttaa aatggattct gatttttgta
     2041 gttcgaattc tttaaaattt gaaaaatact gataatcatc ataataggga gcatcatact
     2101 gtttccaaac tggattaagt tgtgaataag ccatttccca taaagacatc aaatcttctc
     2161 tctttaactt tcttaaataa atcatactat tcccctaatc caaggccttg acttccaaca
     2221 tcatatcacg gatctgagcc gccagttcaa agtcaagcac ttcgacggct tcttgcattt
     2281 gtttttctag tttcttgacg agttctttgc gctcttgttt gttgaggcta ttgatgtcga
     2341 cttccttgtc ctcttcctta gcaactgcct tggtcacggc aatcaggtca cggatttctt
     2401 tcttgattgt ctgtggtacg ataccatgct cttcattata ggccatctga attttccgac
     2461 ggcgggcagt ttcatcgata gcacgttgca tagactgggt aaccgtatct gcatacatga
     2521 tgacatgacc ttcactgtta cgggcggcac gcccaatagt ctggatgagt ccacgctcgt
     2581 tacgaaggaa accttccttg tcagcatcga gaatggcaac caagctaacc tcaggaacgt
     2641 caatcccttc acgaaggaga ttgattccaa ccaagacatc aaagacaccc aagcggagat
     2701 cacggataat ctccgtccgt tccaaggtct tgatatccga gtgcatgtac ttgaccttga
     2761 tgcccatttc cttgaaatag tcggtcaagt cctctgccat tttcttggtc aaggtggtga
     2821 taaaggttcg ttcattcttt tcaacacggg cattgatttc acctaagaga tcatcaatct
     2881 gtcccatagt cggacggact tccacctcag gatccaaaag ccctgtcggt cgaatgattt
     2941 gctcaatcac cgtctcagtc tgttcatttt catagtcacc aggtgtcgct gatacgtaaa
     3001 caatctgatg cacatggctt tcaaactcct cacgacggag aggacgattg tccaaggcag
     3061 acggtaaacg gaaaccataa tttactagca tttccttacg cgaacggtct ccattgtaca
     3121 tgccttttat ttgtcccata gtcatatgac tctcgtcaat cataatcaaa aaatcatctg
     3181 ggaagaagtc gagaagcgta taaggaggct caccttcact acgtccatcc atgtggcgag
     3241 aataattttc aaccccattt gtatagccca tctcgcgcag catttcgata tcgtactctg
     3301 tccgttgttt caagcgctgg gcttcaagca atttaccttc cttctcaaag acagctaact
     3361 gctcttctaa ttctgcttga atcttggcaa cggcaacttc catatggtcg tcattggtca
     3421 caaagtgtgt cgctgggaaa atcgctaaat gatccacttc tcccagcacc tgacctgtca
     3481 gagcctcaac ttcacgaata cggtcaattt cgtctccaaa aaattctact cgaaaggcat
     3541 gttcatctcg ggaagctggg aaaatctcta ccacatcccc acgaacgcga aatcttccgc
     3601 gttggaaatc aatatcatta cgttcaaact gaatatcgac caagtcattc aagagtttat
     3661 cacgagaaat ctctagacca ggacggagac taacgacact atcagcgtat tccttgggcg
     3721 aacccaaacc atagatacaa gagactgagg ccacgacaat aacatcatta cgctccaaaa
     3781 gggctgaggt agctgagtgg cgaagcttgt caatctcgtc attgacagaa ctatccttct
     3841 caatataggt atcgctagaa gggacatagg cctctggctg gtaataatca tagtaggata
     3901 cgaaatactc aactgcattt tcagggaaaa attccttaaa ctccccatag agctgaccag
     3961 ccagagtttt attgtgggca ataaccagag ttggtttatt gactttagaa atgacctgac
     4021 tcatagtata ggtcttccct gttccagtcg cccccatcag aatctgagct ttttctcccc
     4081 cctcaatgtt atccaccaac tgctcgatag cttggggttg atctcctgat ggttgatatt
     4141 ttgatactag tttaaattga ttatctgtaa tgtgattgat cataagaatc ctctctccat
     4201 gtgctattcc tattttagca tacttatagt attttcacga agaaaaggac ggaccgaagt
     4261 cacatccttt cattttcttt ctttaattta ttagcaagat agacaatcag cagtagtaat
     4321 accagacttg tcataatgga accttctatg ccaaaagaac cacctgatag ccaatcttga
     4381 ttgccttgtg gtaaaaaggt catcagagac gttcctgacg gttgaccact aactaaaatc
     4441 ccaaagagat taccctgagc aaaattccaa gcaccatgaa tacctgcaac accccaaact
     4501 gtatcagttt tgagaaggta aagagccatg gtaactccga ataaaaagag atttactaga
     4561 gatagagggg tgaggccaga attgcccata tgaagcaggg taaagaacag gctagatata
     4621 agaatagcta gttttagatt ggttcttgag gccaattgag gaagtagcca agcacgggcc
     4681 accacttctt ctgctgtccc ctgtaaaatc caaaatggga tagtaaagac gacaaaggca
     4741 agagaataag gattcaagtg aatggattcc aaacgatatt gatctaagac cactaaacct
     4801 aacaaggtca gaagaaaaag tgccaggcct agactaaatc ctttcagaag attgctgagg
     4861 aaattctctc tataaaatcc caaggttcga ataggtcttt tctcaacttt tcttgtccat
     4921 ctgaacacag tgttaagaat aaaaccaaag gccagtaatc ctaaaattaa acgaaagtca
     4981 cttgttttat ccatcaagct ctgatgcaag gtctgcaagt agcttgcaag attttgacca
     5041 gcctctccaa aatttctagc aagcccgatg agagctaaca aactaatacc atataaagta
     5101 taagccacaa actctcctat gaagacaaaa acaaaggcta acaaggggct tgtgtaaatg
     5161 tttaaattca tttttgaagc ttggaagtct ttaaatattc ttttgttctt catatccccg
     5221 tcctcttttc ttctatatat actattatta tagcactttt taatagcaat tcaagaaaga
     5281 aaaggaaaaa tcaatgttat attttctgac acgaaaatat aaaaatttgc ctttttttac
     5341 tttttctgat ataatgagag aatattcgga aaaggagact aaaaatgaag aaaaaatttc
     5401 tagcattttt gctaatttta ttcccaattt tctcattagg tattgccaaa gcagaaacga
     5461 ttaagattgt ttctgatacc gcctatgcac cttttgagtt taaagattca gatcaaactt
     5521 ataaaggaat tgatgttgac attattaaca aagtcgctga gattaaaggc tggaacattc
     5581 agatgtccta tcctggattt gacgcagcgg tcaatgcggt tcaagctggg caagccgacg
     5641 ctatcatggc agggatgaca aagactaaag aacgtgaaaa agtcttcacc atgtctgata
     5701 cttactatga tacaaaagtt gtcattgcta ctacaaagtc acacaaaatt agcaagtacg
     5761 accaattaac tggcaaaacc gttggtgtta aaaacggaac tgccgctcaa cgtttccttg
     5821 aaacaatcaa agataaatac ggctttacta ttaaaacatt tgacactggt gatttaatga
     5881 acaacagctt gagtgctggt gccatcgatg ccatgatgga tgacaaacct gttatcgaat
     5941 atgccattaa ccaaggtcaa gacctccata ttgaaatgga tggtgaagct gtaggaagtt
     6001 ttgctttcgg tgtgaaaaaa ggaagtaaat acgagcacct ggttactgaa tttaaccaag
     6061 ccttgtctga aatgaaaaaa gatggtagtc ttgataaaat tatcaagaaa tggactgctt
     6121 catcatcttc agcagtgcca actacaacta ctctcgcagg attaaaagct attcctgtta
     6181 aggctaaata tatcattgcc agcgattctt cttttgcacc ttttgttttc caaaattcaa
     6241 gcaaccaata cactggtatt gatatggaat tgattaaggc aatcgctaaa gaccaaggtt
     6301 ttgaaattga aatcaccaac cctggttttg atgctgctat cagtgctgtc caagctggtc
     6361 aagccgatgg tatcatcgct ggtatgtctg tcacagatgc tcgtaaggca acttttgact
     6421 tctcagaatc atactacact gctaatacca ttcttggtgt caaagaatca agcaatattg
     6481 cttcttatga agatctaaaa ggaaagacag tcggtgttaa aaacggaact gcttctcaaa
     6541 ccttcctaac agaaaatcaa agcaaatacg gctacaaaat caaaaccttt gctgatggtt
     6601 cttcaatgta tgacagttta aacactggtg ccattgatgc cgttatggat gatgaacctg
     6661 ttctcaaata ttctatcagc caaggtcaaa aattgaaaac tccaatctct ggaactccaa
     6721 tcggtgaaac agcctttgcc gttaaaaaag gagcaaatcc agaactgatt gaaatgttca
     6781 acaacggact tgcaaacctt aaagcaaacg gtgaattcca aaagattctt gacaaatacc
     6841 tagctagcga atcttcaact gcttcaacaa gtactgttga cgaaacaacg ctctggggct
     6901 tgcttcaaaa caactacaaa caactcctta gcggtcttgg tatcactctt gctctagctc
     6961 ttatctcatt tgctattgcc attgtcatcg gaattatctt cggtatgttt agcgttagcc
     7021 catacaaatc tcttcgcgtc atctctgaga ttttcgttga cgttattcgt ggtattccat
     7081 tgatgattct tgcagccttc atcttctggg gaattccaaa cttcatcgag tctatcacag
     7141 gccaacaaag cccaattaac gactttgtag ctggaacaat tgccctctca ctcaatgcgg
     7201 ctgcttatat cgctgaaatc gttcgtggtg gtattcaggc cgttccagtt ggccaaatgg
     7261 aagccagccg aagcttgggt atctcttatg gaaaaaccat gcgtaagatt atcttgccac
     7321 aagcaactaa attgatgttg ccaaactttg tcaaccaatt cgttatcgct cttaaagata
     7381 caactatcgt atctgctatc ggtttggttg aactcttcca aactggtaag attatcattg
     7441 ctcgtaacta ccaaagtttc aagatgtatg caatccttgc tatcttctat cttgtaatta
     7501 tcacactttt gactagacta gcgaaacgct tagaaaagag gattcgttaa tggcaaaatt
     7561 aaaaattgat gtaaatgatt tacacaagca ctatggaaaa aatgaagtcc taaaaggaat
     7621 tacgactaag ttctatgaag gagatgttgt ttgtatcatc ggtccttcag gttctggtaa
     7681 gtcaactttc ctccgtagcc tcaatctttt agaagaagtc actagcggtc acatcactgt
     7741 gaacggctat gatttaactg aaaaaacaac caatgttgac cacgtccgtg aaaatatcgg
     7801 catggtattc caacacttca acctcttccc tcatatgtct gtattggaca acatcacctt
     7861 tgctcctatt gagcacaagt tgatgactaa ggaagaagct gagaaattgg gaatggagtt
     7921 gcttgaaaag gttggactag cagataaagc taatgccaat ccagatagcc tatcaggtgg
     7981 tcaaaaacaa cgtgtggcca tcgctcgtgg cctagcaatg aatccagaca tcatgctctt
     8041 cgatgaacca acttctgccc ttgaccctga gatggttgga gacgtactta acgttatgaa
     8101 ggaattggct gagcaaggca tgaccatgat tatcgtaacc catgagatgg gatttgctcg
     8161 tcaggttgcc aaccgcgtta tctttactgc agatggcgag ttccttgaag acggaacacc
     8221 tgaccaaatc tttgataacc cacaacaccc tcgtctgaaa gagttcttag ataaggtctt
     8281 aaacgtctaa actcaaactg taaggatttc cttgcagttt ttctacctcg tattggaatt
     8341 tttgattttt cggaaaatta tgttagaatt aagtttatga aatgaggttt cctcatacct
     8401 agcaagacta ggaataaaaa tagaaattag gtagctagat gtcatctaag gttattgtta
     8461 caattttcgg tgcgagtgga gacctggcta aacgcaagct ctacccttcc ctttttagac
     8521 tatatcaatc cggcaatctt tccaagcact ttgccgttat tggaactgcc cgtagacctt
     8581 ggagtaagga atattttgaa tctgtagttg tcgagtccat ccttgatttg gcagatagta
     8641 ccgagcaagc ccaagaattt gctagccact tctactatca aagccatgat gtcaatgatt
     8701 cggaacatta tattgctttg cgtcaattac aagctgagct taatgaaaaa taccaagctg
     8761 aacacaataa gctcttcttc ttgtctatgg cacctcagtt ctttggaacc attgccaaac
     8821 acctcaaatc tgaaaacatt gtcgatgaca aaggttttga gcgcttgatc gttgaaaaac
     8881 catttggtac agattacgca actgcaagca agttgaatga cgaactccta gcaacatttg
     8941 acgaagaaca aattttccgt atcgaccatt atcttggtaa ggaaatgatc caaagcatct
     9001 ttgcagttcg ctttgcaaac ttgatttttg aaaacgtttg gaacaaggat tttatcgaca
     9061 atgttcaaat tacctttgcg gagcgcttgg gtgtagaaga acgtggtggc tactatgacc
     9121 aatccggtgc cctccgtgac atggtccaaa accacactct acaacttctt tcgcttctcg
     9181 ccatggacaa accagcaagc ttcacaaaag acgagattcg tgctgaaaag attaaggtct
     9241 ttaaaaacct ctatcatcca actgatgaag aactcaaaga acactttatc cgtgggcaat
     9301 accgctctgg taagattgat ggcatgaaat acatctctta tcgtagcgag ccaaatgtga
     9361 atccagaatc aacaactgaa acctttacat ctggtgcctt ctttgtagac agcgatcgat
     9421 tccgtagtgt tcctttcttt ttccgtacag gtaaacgact gactgaaaaa ggaactcatg
     9481 tcaacatcgt ctttaaacaa atggattcta tctttggaga accacttgct ccaaatattt
     9541 tgaccatcta tattcaacca acagaaggct tctctcttag cctaaatggg aagcaagtag
     9601 gagaagaatt taacttggct cctaactcac ttgattatcg tacagacgcg actgcaactg
     9661 gtgcttctcc agaaccatac gaaaaattga tttatgatgt cctaaataac aactcaacta
     9721 actttagcca ctgggatgaa gttggtgcgt catggaagtt gattgatcgt attgaaaagc
     9781 tctgggctga aaatggtgtc ccacttcatg actataaagc tggaagcatg ggacctcaag
     9841 ccagctttga cctacttgaa aaattcggtg ccaaatggac ttggcaacca gatatcgcct
     9901 atcgtcaaga tggtcgctta gaataaaaaa atcctgcaag tttgtacctt gcaggatttt
     9961 tgcttctgat tagattaagc cttccaagag acctttcata aagttttctg agttaaactc
    10021 tccaatatca tcgatttttt caccaaaacc aatcaatttt acaggaatat tgagttcttc
    10081 acgaatggct agaaccacac ctcctcgagc agttccatca atcttagtca aaacaattcc
    10141 cgttaaaggt gtgattttcg aaaattcttt ggcctgtact agggcatttt gacctgttga
    10201 tgcatcaagc gccaagaagg tttcatgtgg tgcttctggc acaacacgtt tgataatacg
    10261 accaatcttt tccaactcag ccataaggtt atccttattt tgcagacgac cagcagtatc
    10321 aatcatgaga atatcgatac cttcagccac ggcacgttcc ataccatcaa agaccacgct
    10381 ggctggatca gctttttcag gtccagttac tactggaaca tctactcgtc ggccccattc
    10441 agctagctga gctactgcac ccgcacggaa ggtatctgct gcaaccagca tgaccttctt
    10501 accagctcgt ttgtagcggt gagctagttt tccgatagaa gttgttttcc caacaccatt
    10561 cacaccaaca aagagcataa ctgtcaagtt atcttggaag tggatgcttt catcgtagct
    10621 accatccttt tcataaagct caaccaattt ctcaatgatg acacgacgaa gtgcatcagg
    10681 tttcttggca ttttcaagct tggcttcgta acgtagttcc tccgttaagt tagaagcgac
    10741 ttggacacca acatcactca taatcaacag ttcttccagt tcctcgaaaa attcttcgtc
    10801 aacagagcgg aagttagcaa agaaggcatt caagcgggca ccgaaacctg tgcgagtttt
    10861 cttaagactg cggtcatatt tttcctgaac agtttcttct gtttgaggcc tttctgcttc
    10921 aagaatttca gaattatttt cttctacagt ctctagaaac tcagtattcc cttcttctga
    10981 gtgtggaaat tctttgactt ctttttgaga aacttctata actggctcta aatccagact
    11041 ttcttcaact gtgtcttgga tttcctcttc ttggaacaca gcttgttcaa caatttcaac
    11101 ctctgcttct tcctgagaaa cttcctcaac ttctgtgaag gtaggattaa catcttcaga
    11161 caaatcaaga ttttccagag cttcttttac aacttcttcg attttaggtt cttctttttt
    11221 tccgaataga cggtcaaaca atcccatatc ttagttctcc tttagcacat attcttcgat
    11281 agcccaggcg acagcttcct catcgttggt catcggcgtc actacatttg cggctgcctt
    11341 tacttcagga acagcgtttt gcatagcaac accaagacct gcccattcaa tcatagagag
    11401 gtcattggcc tcgtcaccac aagccatcac ttgactttgg tcgattccaa gatggctgat
    11461 tagttttgcc aaacctgttg ctttatgaac attctttggt gaccattcta gcaacatttc
    11521 acgtgattta aagatttcat attggtcaaa caattctgga gaaatcttct gaatggctgc
    11581 atccaagggt tcttgagcaa aggcagtcac gcatttgttg taggtcattt gactagataa
    11641 gtcttcaaag tccactggaa caaaggtcaa agctggattg aatttggcat aaagactttc
    11701 ttggtccgat tggatttgat aaactgttcc ttctgagatg gcatcaagag gcagtgataa
    11761 tttctctgtt tcttcataca aacgtgccac atcatcatat gaaaagactg ttttatcaag
    11821 gatttctcct gtatttttct gaactaatcc accattaaaa gtaatggtat actcatcttc
    11881 ctgaccgtca gtccctaact catggagaaa gaaatccatg gcttttaagg gacgaccagt
    11941 tgtcaatacg accttgatac cacgatcacg cgcagctttc aaggtttcct tggtacgatc
    12001 cgtcagcctt ttatcagtag tcagcaaggt cccgtccaag tccaatgcaa tcaattttat
    12061 atctgccatt ataagccctc catataagct ataaccgacc gttccttatg gtgaccaatc
    12121 acagtctttg ctaattctaa aatttcaggt cgtgcatttt caggagctac aggatgtccc
    12181 acaacctgca tcatatgtaa gtcattaaga ttgtctccaa aagccatgac ctgatccatt
    12241 gtgataccaa gttttttagc taattcaaca atagctacac ccttatcgac atagtccaga
    12301 acaatatcaa tagattcaaa gccagttgtc atagccttga caccagggac attatcattg
    12361 acccaagctt caccagcttc cagcgtttct tctgtgaagt tggttgtaaa tttgaaaatg
    12421 tcatctgtga tatcttccaa actcgctact ttttggatat tttcattata atgctgactc
    12481 actttcaaat aggtctcatc aaccgtatct agaacatatg aacccttctt acccgtcaag
    12541 agcagtttat tgatatctac ataaggtgac gttttcagct tttcaaaagt tgccagataa
    12601 aagtcacgag acatagtcgc ttcatacaag tcctgacctt gatactctac caaactgcca
    12661 ttttccgcga tgaaaataat gtcatcacga acaccagcaa ataatttttc cagagacaga
    12721 aatccccgac ccgaagccac cgcaaagtaa atcccttttt ccttgtagga agccaagaga
    12781 gacttgagac gatccatatc aaagcgtcca ttcccatcta ggaaggttcc gtccatatcc
    12841 gttgctacta gtttaattgt catccttcaa tactttctaa atcttttaac ttaactgaaa
    12901 caatctttga aacacccgat tcttgcatgg tcactccata gatagaatcg gccgctgcca
    12961 tggtcccctt acggtgggtt acgacaataa attgactgtc cttatcaaag cggttgagat
    13021 aatccccgaa acgtttaaca ttggcttcgt ctagcgcagc ctctacctca tccaagatga
    13081 caaaaggaat ggtcttgaca cgaataatgg agaaaagcaa ggcaagagcc gatagagctt
    13141 tttcaccacc actcatgagg ttaagcgact ggattttctt acctggaggt tgaacagaaa
    13201 tctccacacc agctgttaaa aggtcgccct cagtcaatat caagtctgcc tgacctccgc
    13261 caaacatctg cttgaaggtc actttaaagg actcacgaat agcttcaaag gttgatttaa
    13321 agcgttcctt gacctcatca ttcatctctg taatggtttc aaggagcaga tttttcgctg
    13381 acaaaatatc atctcgctga ctatttagaa agtccagacg gttgtgaact tcttcgtact
    13441 ggtcaatagc ttctatattg acaggaccca gtgagcgaat agccttctct aaatccttaa
    13501 cttcttgctc tgccagattg aggttttcca attcatgcgc tttttctaga gcttcagtat
    13561 agctaatctg gtactggtct gttaattgac tttgtagatg gcgcaagcgc tcgctgacct
    13621 tttctttctt ggcttcagca cgtgtttgct tgcgaatcca ctcctcattc tgctggcgag
    13681 cttgatccaa gtgactggca atatcatcca gttgaccttc tatatcatcc aactcaaact
    13741 gcttgcgaat caaaccttgt tggagatttg ttttctgagt tttggattct tccgcctgtt
    13801 gactgagcaa ttctgtatca accttctcaa gattgtcaac tttttcttgg agcatgcgct
    13861 ggatttcttc ttgttcgata ttaagattgt ccaattcctt gcctaagcgt tcaatatcag
    13921 caacttcata acgtttttgc ccttgcagtt ctgtcttaag caaacgagct tgcgctagct
    13981 cttcctgcaa gttttgatag cgttcttgga tggcattttt gttagactta atctcttcaa
    14041 tctcagcttc cagattttgc ttgtcactgg cgatagtagc aaggcgttct tggcattttt
    14101 ccttgtctgc ttgccaatct ccatcagaaa gacgatttaa ttccttttct tggagtttcc
    14161 aaagagtttc tagctcttca acttgctgac tagtttgctg ataagcgagg aacaagcctt
    14221 gctcctgaat acgtgcctgc tctccttgag atttaatagc ttctaatgac tcgatcaatc
    14281 tggccatctc atcttgcaag gtcttcaaag ccacttcttc tgaatccaag cttgcttctt
    14341 cttcagcaat ttctttttgt aattgctcca gttctggctt gatgaagatg ctgttgttct
    14401 gacgattggc tccacctgca taggaaccac ctgtacgaag ctctgtccca tccaatgtca
    14461 ccatgcgaac ctgataacga acttgtcgag cagcttcacg cgcatgttct acggtatcaa
    14521 agatagccgt cgtagctagc aagttcttga aaatggcttc cagtctagta tcgaaagtaa
    14581 ctaactcatc tgccatccca aggaaacctg ggcttacagc gatagcatct tggttctgac
    14641 tagaaatcgt acgcgcctta atagtggtca aaggaagaaa ggttgcacga ccggctctgt
    14701 ttcgtttgag gaaatcaatg gctttggttg ccgcattctc atcttctaca ataatgtgct
    14761 gactactcgc tccaagtgca atttctaggg cagtttgata atgcatatca aaggtcagat
    14821 gctcactgac tgcaccaata atcccaccta ggcgatcttt ttcttggaga acactcttaa
    14881 cacctgcata aaagttacta tgatttctca ggatattttc caaactttga gctctggcct
    14941 gcttgttttt gagattatcc agacggtcaa agagttggct ttgttgagct tgataggaag
    15001 ttttctgctc ctcttgctcc ttggcaatag cttggtagtc agccaataat ttctgaacct
    15061 gctccttggc agtttcaagc tcttcctttt gctgactagc cttctcttta gctatagcca
    15121 attgctcttt cagcttttct agttgatctg cttgtttttg agaaagctga cgactatttt
    15181 ccaactcatt ctcaatacgg gtcaactggt ttgagacatc cgcttcttct tgtaaaagag
    15241 ctacaaagcg ttcacgtaag agctcaatca tctgatcagg atcgtctgag aaagccagca
    15301 attcagcttc taaacgattg agtttttgat tattttggac tagatttccc tctaacagag
    15361 ctaaagagct ttctttatca gacttttctt tgctgagtga atttctctta tcctccaaag
    15421 cagccaaacg agcttgtacc tcctgttgat tcaaggccac ttgctcggac tccagtttcg
    15481 atagggctaa ttttctttct aaatcactaa tcagactagt caagtccatc aaactgcctt
    15541 ggtctttggc catttcagcc tgtaaatctt ggcgttgctt tttaagagtt tgattttctt
    15601 cttctaattt ttcacgcttt tggtaataac tcatcaagag ttcttgaacc tgagccaact
    15661 cttcttctgt cgactctagt tcagccttat tttccttgat ttgagcaacc agaacgtcta
    15721 aataaatagc cttacgttgt ccttccaagt ctaaaaactt acgggcattc tcagcttgct
    15781 tctcaagagg cttgatttga ttatccaact cgtagataat gtcctctaag cggtccagat
    15841 tatcctgagt ttgctgcagt ttactctcgg tttcttttct gcgagtcttg tattttaaaa
    15901 ctccagcagc ttcttcaaaa atagatcgtc gttcctcagg cttggaatta aaaatctcct
    15961 caaccttccc ttgggaaata atagagaagg aatctcgtcc caatccagta tccaagaaga
    16021 ggtcatgaat atcacgcaga cggactttct tgccgtcaat cttgtattcg ctatctccac
    16081 tacgatagat atggcgttcc accctgattt cttgacctgc atccttgata aatccgtcat
    16141 gattatccag agtcacaact acagaagcat aattgagcgg tttgcgactt tcggttccag
    16201 caaagatgac atccggcatc ttgcccccac ggagactctt gacactagac tcccccaaag
    16261 cccaacgcag actttctgta atattggact ttccagatcc attgggtcca acaactgccg
    16321 tcacaccttg gtcaaaaacg accttggtct tatcagcaaa agacttgaac ccctgaattt
    16381 cgatttcctt taaatacatg aatccagccc cttctcaacg gcatttttgg cagcttcctg
    16441 ctctgctaat ttcttagaac gaccttggcc ttgaccgatg ctcttacctt caacaagaac
    16501 ttctacatca aagaccttat cgtgagcagg ccctgtttca gaaatcacct gataacgaat
    16561 agccacatca ccattgacct gaagcaactc ttggagatgg gttttatagt ctgtaatcat
    16621 ctcaaactcg cctgcttcaa ccttaggaat catgacttga tagataaatt ccttgacctt
    16681 ggccacatcc ttatccaaaa gaagggcacc aagaaaggct tcaaaggcat caccaagaat
    16741 ggtgtcacga ttgcgaccac cagatttttc ttccccttta cccaacttga taaactggtc
    16801 aaactggcaa tcacgcgcaa aaccagctaa actctcctca cggacaatca tagcacggag
    16861 ttttgatagg tcaccttcag gctttttagg atatttttta tatagatatt ctgaaatcaa
    16921 taactgtaga acagcgtctc ctaaaaattc caagcgttca ttgtgtgaaa tttttaagag
    16981 gcggtgctca ttggcataac tcgtatgagt aaaggcagtt tccagtaact ttttgtctgt
    17041 aaattcgatt gcaaaatggt tctttagtac agtttgtaat tctttcatac caacctcttt
    17101 ctaactgata atagtccttt ttattatatc aaaaaaagcc ccctgagtca ctctaaaacg
    17161 ggactggaaa gcatttggga attctttaga cagagattct cagttttagc ggcaaatttg
    17221 ggtcaggata aagaaaaaag ccctattaaa ggctttttag gatgtttaca tccaccctga
    17281 gggaatcgaa cccccatctc aagaaccgga atcttacgtg atatccatta cactaagggt
    17341 ggaaacttgt tttattataa cagaaatttg ctctaataac aagttttttg gtcaaagacc
    17401 ccgtcttagt gggaagcatc cccattccag atggagtttt tcacgatcac ataatcaacg
    17461 tgtttaaggt cagcaacctg acgtccacct gcataagaaa tagcactttg aaggtcttgt
    17521 tccatctcag ttaaagtgtc ttgcagatga cctttagcag gaagcaagat acgtttgcct
    17581 tccacatttt tgtaagcacc tttttgatat tgtgaggctg aaccataata ttctttgaac
    17641 tgttcaccat cgacttcaat cgttttccct ggactttcaa tgtgtcctgc aaagagggaa
    17701 ccaatcatga tcatgctagc accgaagcgg atagacttag caatatcacc gtgagtacga
    17761 attcctccat cagcgataat cggtttacgc gcagccttgg cacaccagcg tagagcagcc
    17821 aactgccaac cacctgtacc aaaaccagtc ttaaccttgg tgatacaaac cttaccagga
    17881 ccgattccga ccttagtagc atccgcacca gcattttcca attcacgcac agcttctggt
    17941 gttcccacat ttccagcaat gacaaaggta tctggcaatt ctttcttgat gtgttgaatc
    18001 atagaaatca cgctatccgc atgaccatga gcaatatcaa tagtgatata ctcaggagca
    18061 tcagccttga gctggctaac aaaatcatac tcataatcct taacaccgac agagatagaa
    18121 gcaatgagcc cttgatcgtg cattcgttta ataaaaggaa tgcgtcctgc ctcatcaaaa
    18181 cggtgcataa tgtagaagta accaccttta gccagttgct ctgctacatt ttcatccaaa
    18241 atcgtctgca tattcgctgg cacaacaggt agtttaaagg tgtgatttcc taaagtgaca
    18301 cttgtatccg cttctgcacg gcttttaatg acacatttat ttggaatcaa ttgaatatct
    18361 tcgtaatcaa aaattggaaa ttcatttaac atatcgatgt ctcgtttctt ttgtaatgac
    18421 ctacctatgc tcttgcatca ctacgccttt tccgacgttt ccttaattta ttataaacca
    18481 aagtacagtt tttgtcaaat tattttatga attaaaatat atcgttcggg ttttacttgt
    18541 gttaaaaata aaagaaagag gggaaattat tttctcccca cttcttcatc aataatcgct
    18601 ttaaaatttt cttctgaatt ttccatcatt ttacaaaatg tactatagaa tgaggcattc
    18661 tgagggattc gaatagacca cttcttcaat tgagctccat agccagctac ttttcctatt
    18721 tcactattta ctgactgctc catactagga aaaatcagtc cagccttctc agcttttaaa
    18781 atataagaat aggaaatcag ctggaataag tcctcacggt tgattccttt ttcagtcaat
    18841 tccagttttt tatattttgc atctagaaca atctttcgtt ctctgtcata aaaatctgga
    18901 tatacttttc gtttcccaac agaaaatact gaaattccat ccgtcttatc cttatttctg
    18961 ggatgtacaa aaccttttgg caacaaggtg taaacatact cttcccaaag ccaggcaaca
    19021 tcaaagagaa taccatagat tttttgatct tgatacccta aaccgtgctt ttcttggttt
    19081 aggatcatca gacaaagttc ttgtaagttt ctgtactcgt gaaagtatgc atgacgtata
    19141 ggtttagatt gatttccccg aataatctta gcacgatcag ctagtttata agagggcgtt
    19201 acacgcacga tttcagatac gttttcacga ctagttgaga gattatctag taccccttga
    19261 ccaatgcttt tctgattctt aatgtattca atagtgtgac ggaccaactg catgagggga
    19321 ttatcatagg tgaactctct cgttgcgtag gcaatatttc ccgtgaaagg aagatttttc
    19381 ttgagatggc ttcttacatc aatcactccc ttaacatgac tgtcgttatg agaaaatcga
    19441 tgatattcct tataaagacc ttttcgaata gcagcttgta gatacttggg aaagagatac
    19501 accaaaagtt gataaagcct ctcttcacga gacaaagcaa catctaaact agtgagattg
    19561 atatgaagaa ccttgtttaa gagataatgc aaaaaatggt cattactctc atcagaaaat
    19621 cgtgaggaaa tcgttaatct ttcctgacca tatccaagaa aaccaatcac gttccctgtc
    19681 ttgattttct gattgactgt ttcaaaaatc ttttggtcct tatccaaatc aggagtatga
    19741 gtcaaatcat ttggaaaaat gaaaatacgt tcatcttggg atagactttc caaggttctg
    19801 tctaaaagaa gattgcttag tttaggatat tcttcaacaa atttttcttt aataatcttg
    19861 tgttgattat cagtaatccg catcatcgtt ttcatcacct tcattgtcat cagctactgc
    19921 ctgatctttt tgctcattat ttgtcagttc aaatgctttt ttcaaagttt ccaaagtttc
    19981 aacctcatca taagaacctc gcaagtagtc ttctaggaga ggcttaatat aatcagacca
    20041 gagtaattca tagtcaaaat ctacatcctt caacttaaga aaataacttg gtccaatatg
    20101 ataatgactg tttaattcct gaacattttc gatagcagcg ttcaagtttc ttagacgaat
    20161 ttttgcttct tctgcatgga tattcagctc tttacccaac atgccaactt gaccctcggc
    20221 agtaacttca acaaaacgaa aacgacgacg catagcaaaa tcaaaggtat ccactgaacg
    20281 atcaatatca ttcatagttc cgatgatgta aacattttcg gggatataga acttttcatc
    20341 agtttcgtgt agatttgcat attgggtaga aacacttcct ttttcaccac gatagccagg
    20401 gtcgatagag aaaaagagtt cgccaaaaat cttagaaatc tccccacgat tgatttcatc
    20461 gatgatgaag acgaatttct tatcagtatc aatttctgtt ggggaaacat agtctttcaa
    20521 accaaatctc tttctcaatg tttctaggac agtttttcca ccacttttgt agtattcttg
    20581 cttattataa tttttatctt tatacaactc gtaaacatat ttgctaggta gtgaccatcc
    20641 tggaacacca ctatcataat ttactgacaa attttgtcta ctattaacag ataagtaaga
    20701 tgtttttgtt atatattctt tttcttcagc aacatttata tattctaagt aagaatccca
    20761 agcctcatca aaattatctt gtcctccaat caattgggtt tcttttgctt tctgacaaaa
    20821 atctttaaaa ataccgtcct gtagcctaaa ctcaatagct ccatccccat ttgatactgg
    20881 tcttaaacct tctacaaaat ccgtataatc atatgatggg tgaaattgta caaatccgat
    20941 ttggtcttcg ttgccatccg ttaattcttt ggcaatttct ttagcaagat aagtctttcc
    21001 tgtgccagga gcaccacgaa ggataaggtt tggagacttt aatagagatt gagttaattg
    21061 atgacgaaaa ttgtttgatg aatccattgt actattgtct tccttatttt ccataaaaag
    21121 cttagaatac tcaaaaagca tagttcctac tttcgatggc tccaactcag gataagtttt
    21181 ggacaccagt tcaattattt tatgattttg cagataaggt ccaccttgat ttgtctgaga
    21241 aacaaagtgg ttccaaaatt ctttctgact attaatattt acaccaaaga aaggatctcc
    21301 ctcagaatag atacaaagta attttgtcac catagcagaa cgaccaataa attcatttgt
    21361 tgatcttttc atatcaaaaa taggattttc aaagttaaaa cgaatacctt ctttgataat
    21421 ttcatacaaa tctgatttta attttgaaaa tcgctgatcc aactctgaaa tc
//
LOCUS       DAVHSL010000035        21173 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000035 DAVHSL010000000
VERSION     DAVHSL010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.036"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            131..607
                     /locus_tag="VVR39_001382"
     CDS             131..607
                     /locus_tag="VVR39_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030864.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1262..1675)
                     /locus_tag="VVR39_001383"
     CDS             complement(1262..1675)
                     /locus_tag="VVR39_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6030865.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS"
     gene            complement(1653..2114)
                     /locus_tag="VVR39_001384"
     CDS             complement(1653..2114)
                     /locus_tag="VVR39_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6030866.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLIALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKEIAMGKSKADDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2077..2337)
                     /locus_tag="VVR39_001385"
     CDS             complement(2077..2337)
                     /locus_tag="VVR39_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030867.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2342..2821)
                     /locus_tag="VVR39_001386"
     CDS             complement(2342..2821)
                     /locus_tag="VVR39_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU6030868.1"
                     /translation="MDASRKNRLKPIKNTMINKILVKSLKIKAFTMLESLLVLGLVSI
                     LALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQK
                     LPVPKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2739..3062)
                     /gene="comGC"
                     /locus_tag="VVR39_001387"
     CDS             complement(2739..3062)
                     /gene="comGC"
                     /locus_tag="VVR39_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU6030869.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQNTS
                     QIVKD"
     gene            complement(3064..4080)
                     /locus_tag="VVR39_001388"
     CDS             complement(3064..4080)
                     /locus_tag="VVR39_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU6030870.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNFFSSGFHLVETISFLD
                     RSALLDKQCVTRMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4028..4969)
                     /locus_tag="VVR39_001389"
     CDS             complement(4028..4969)
                     /locus_tag="VVR39_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU6030871.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAVKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5045..5410)
                     /locus_tag="VVR39_001390"
     CDS             complement(5045..5410)
                     /locus_tag="VVR39_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU6030872.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5561..6619)
                     /locus_tag="VVR39_001391"
     CDS             complement(5561..6619)
                     /locus_tag="VVR39_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU6030873.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLDTALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6782..7933)
                     /gene="nagA"
                     /locus_tag="VVR39_001392"
     CDS             complement(6782..7933)
                     /gene="nagA"
                     /locus_tag="VVR39_001392"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU6030874.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8086..9903)
                     /locus_tag="VVR39_001393"
     CDS             complement(8086..9903)
                     /locus_tag="VVR39_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU6030875.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHRMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10004..11146)
                     /gene="tgt"
                     /locus_tag="VVR39_001394"
     CDS             complement(10004..11146)
                     /gene="tgt"
                     /locus_tag="VVR39_001394"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU6030876.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11276..12133
                     /locus_tag="VVR39_001395"
     CDS             11276..12133
                     /locus_tag="VVR39_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU6030877.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12161..12804)
                     /gene="pcp"
                     /locus_tag="VVR39_001396"
                     /pseudo
     CDS             complement(12161..12804)
                     /gene="pcp"
                     /locus_tag="VVR39_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(12911..13270)
                     /locus_tag="VVR39_001397"
     CDS             complement(12911..13270)
                     /locus_tag="VVR39_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU6030878.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSLLLKNQGIYKALLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            complement(13281..13706)
                     /locus_tag="VVR39_001398"
     CDS             complement(13281..13706)
                     /locus_tag="VVR39_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU6030879.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14029..15141)
                     /locus_tag="VVR39_001399"
     CDS             complement(14029..15141)
                     /locus_tag="VVR39_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6030880.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15307..15940)
                     /locus_tag="VVR39_001400"
                     /pseudo
     CDS             complement(15307..15940)
                     /locus_tag="VVR39_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(15944..17224)
                     /locus_tag="VVR39_001401"
     CDS             complement(15944..17224)
                     /locus_tag="VVR39_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6030881.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17285..18769)
                     /locus_tag="VVR39_001402"
     CDS             complement(17285..18769)
                     /locus_tag="VVR39_001402"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU6030882.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(18845..20122)
                     /locus_tag="VVR39_001403"
     CDS             complement(18845..20122)
                     /locus_tag="VVR39_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU6030883.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20229..20312)
                     /locus_tag="VVR39_001404"
     tRNA            complement(20229..20312)
                     /locus_tag="VVR39_001404"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20276..20278),aa:Leu,seq:caa)
     gene            complement(20322..20393)
                     /locus_tag="VVR39_001405"
     tRNA            complement(20322..20393)
                     /locus_tag="VVR39_001405"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20359..20361),aa:Gln,seq:ttg)
     gene            complement(20404..20476)
                     /locus_tag="VVR39_001406"
     tRNA            complement(20404..20476)
                     /locus_tag="VVR39_001406"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20441..20443),aa:His,seq:gtg)
     gene            complement(20491..20561)
                     /locus_tag="VVR39_001407"
     tRNA            complement(20491..20561)
                     /locus_tag="VVR39_001407"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20527..20529),aa:Trp,seq:cca)
     gene            complement(20566..20646)
                     /locus_tag="VVR39_001408"
     tRNA            complement(20566..20646)
                     /locus_tag="VVR39_001408"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20610..20612),aa:Tyr,seq:gta)
     gene            complement(20659..20731)
                     /locus_tag="VVR39_001409"
     tRNA            complement(20659..20731)
                     /locus_tag="VVR39_001409"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20696..20698),aa:Phe,seq:gaa)
     gene            complement(20735..20808)
                     /locus_tag="VVR39_001410"
     tRNA            complement(20735..20808)
                     /locus_tag="VVR39_001410"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20772..20774),aa:Met,seq:cat)
     gene            complement(20819..20908)
                     /locus_tag="VVR39_001411"
     tRNA            complement(20819..20908)
                     /locus_tag="VVR39_001411"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20870..20872),aa:Ser,seq:tga)
     gene            complement(20991..21064)
                     /locus_tag="VVR39_001412"
     tRNA            complement(20991..21064)
                     /locus_tag="VVR39_001412"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21028..21030),aa:Ile,seq:gat)
     gene            complement(21099..21169)
                     /locus_tag="VVR39_001413"
     tRNA            complement(21099..21169)
                     /locus_tag="VVR39_001413"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21135..21137),aa:Gly,seq:tcc)
BASE COUNT         6324 a         4843 c         3746 g         6260 t
ORIGIN      
        1 tgaaaataaa ggactaaagc aataactcta aatacatctg atttttatag gatatttcat
       61 aaaaaaaatc tacataccta gagtcctatt tagttatgta tcttacataa agagaaagga
      121 attaattatc atgaaattat ctttgtatag tgaagttgaa cattaccatt ttttaagttc
      181 ttattcttta aatgatatta catatactga taccccaaaa aatattattg aaaagtctaa
      241 aaaagataag tatagatacc caatagtaat acttaataaa gaccataaag taattggatt
      301 tttttgccta cacctaaaca ctggtcctaa agagtatggc tattatcaaa atgattatgc
      361 gcttattaga ggattttcta ttcatgataa tttcagaaat caaggatatg gttctaatgc
      421 tctgaatgaa atatttgaat tcatagactc aactttaaaa ttagaaatta accatattat
      481 attggctgta aatgaaaaaa atatattggc tcaaaaagca tatagaaatt ccggtttttc
      541 tgttgtgaaa aaagatttag aaggaaaaag ggggaaatta attattatgg agaaaagcag
      601 aaactagtaa tgatactagt ttctgctttt ctctaagtct gctataaatt tataacatgt
      661 tgaaataaga tgtgaataaa ttgattgcag aattcaaacc aatttctaac aatgttttag
      721 aaaactcggc ggactattcc agattcaatc cactatattc tatcttattt gcatattttg
      781 agagaaataa tctatatact aaacttttat gtttataatt cattcctttc gtttcactca
      841 aggcacaaga cagaatgaaa aagtggtgtg ctctttattt tgttttataa taatagtgag
      901 aaaacctatc actactacaa atcacgggga ggtgaataag tgagtggtat agccactacc
      961 tcgcattttt ataggtgtca ttctttccat caagcacaag aactgtgact aggagcacgt
     1021 aaacttataa ttgaataagc gactcgtttg tgaaaggaaa gaatagtcaa gggataggca
     1081 gactcaaatt tggtgaaggg aaacccctca tgttaaaagc caaacttcaa ttttaaaaat
     1141 tttaaaattt gtttcgtatt cactactcct tgcctttata ttggattgat taagagaacc
     1201 tttcgcgttt ctagaaacta cagtggacta ttctggattc aacacattat agttgaattg
     1261 actaggaatt ctctttcttt tcaggcttct cttctgattt tttcttctcc gctttttcgc
     1321 ttgaatcagt cgctacctct tcctttttat ctcttttctc ttctttgatt ttgactgaag
     1381 gaaacagaaa ctcatattga ctcttatccg tacgaacagt cgtcaccaag cttgttttct
     1441 tgttttgata gcttacctga cctagattaa agacctgttc cccactttct tgctcggctt
     1501 tatccttggt tcgcttggcc atggcaaaag caaccaactt ttctttattt aaagcatagt
     1561 cttgatagtg ggcgatttgt cggttcaagt aaaattgtaa caaaagacta aagatggctg
     1621 ctatggtgac tgcgtagagg agaacacctg ccttaacttt cttctttttc cacacgatag
     1681 atgaactccc tttctaagcc tttttgaaac tggaaacgaa aatgaaccag ttgattgtcc
     1741 tctgtaatct gagctgattt gaggccataa accataggct gataacctcg accacgagca
     1801 ttcgttttac ggaaatcatc tgccttagac ttacccatag caatctcctt gccatcttgc
     1861 ttcatgtata ggcgattgcc ttctactttt tcgaactgcg aacggtctaa ttctgcctca
     1921 agttggtcca caaacaagag ccactccttt tgctcgcttt gttgctggta gcgaacttct
     1981 gaaatgagga gctgactcat agcttgaaaa aggagtaatc ccccactgat gacaatcagg
     2041 gcaatcaggg attctaacaa ggtaaaagcc ttgaccttat ggctctttga ttgccaacaa
     2101 ctgttctgaa ccatggtaga cctccaatcc tttttcacta gaaaatacct gaatctcaac
     2161 tccgttgatg cttacctgat tttgccccgt ctgcaaggcc atcttagcta ccctcaagac
     2221 ttcttccttt tgcaagattt ttgcttcctc ttgcctattt ttttgaattt gtcccaaaag
     2281 gagggtcgca atgctggcaa agatagctag agcgactact gcttccagta aaatcactgc
     2341 cctaattttt tgtttcctta atgcgtttaa tttttccatt tcctagatat aattgatagc
     2401 gaatcgctcc tttactggtc tgaaattcaa ccttagccag ggacgaattg cccccagcac
     2461 ggtcaaatgt aatactttgg cctgatgggg cctgaattcc tttagggact ggcaactttt
     2521 gactgccatt gctaatcatc tgcccatcca agttcagact agtcttttgt tgactagcta
     2581 cactgcgttt ttgggtttcc cgatagagtt cttcaaactc cataaagaaa atctgttcct
     2641 ctaccgctgc aaaagtggac tggacagagc cggacaagcc caaggcaagg atactcacaa
     2701 gtcccaaaac caagagactt tccagcatgg taaaggcctt aatctttaac gatttgacta
     2761 gtattttgtt tatcatggta ttctttatag gctttagcct gttcttccgt gatgcgtcca
     2821 tcgtcttgta actttcttag gctagcatct tcattctttt ccaagctata aagttctgcc
     2881 tggctttcca ccaccttaac aacagctgct tttcctttgt cattgactgc ttctttttgc
     2941 ttggtcagat taggtacaaa gagcaagaaa agcacgctga taatcagcaa gaccaccaac
     3001 atttccacca atgtaaaagc tttaacctta gcttttttca agaatgtcat catttttttc
     3061 attttaaaaa tttacctcca tattttgata catgggcatg agcattgccg cataaagtaa
     3121 aacgataatc agtgccacaa aaataaaaac cagtggctgc accaaattca tggtgcggtt
     3181 gactcgggta aaaaaggctt cccaagtttt ttcagcatag atttccaact cactacccag
     3241 cttggactta acttccccat actctatgat gagactcaat tccttcctaa agaaaggata
     3301 ggttcctatc gtctgagaaa attcacggcc atttttcagg gtttgagcca gatcttgacc
     3361 gatttcttta aagagctggg aaccttgttc ctgcatcatt tgaaaaatct gcgtcagctc
     3421 cattccctgt gaaatcatat tcccccattc acgtgcataa taggctgtca agtaggtctg
     3481 cacaaatatt ccaataaagg gaaggcgtgc taagatagaa aagacactca tcttagaact
     3541 tcttttataa aaagttagtg ctaaaagggc aagcacggaa acaagcccta ccatgcctag
     3601 aaaaatttgt ggcagattac cgataattcg ggtggcaata ttgctactat ccagttgtgg
     3661 gagcaggtaa ttccgtagcc ccagcatgat taagagaaga aaaaacagca aaatcaaggg
     3721 ataggtcgct acttcaatca attttttctt gaccttggcc agattgtcca gatattcttc
     3781 tatctttccc aaactcaggt ggagattgcc atgaacttca gctagggata actgagtgac
     3841 aatagcactt gaacatccca aactttccat catttctgag aatgatttcc cctgagacaa
     3901 gcccacacgc atccgggtca cacactgctt gtccaacaaa gcactcctat ctaaaaagga
     3961 gatggtctcc accagatgaa aaccgctaga aaagaaattg ttaaataggg tgatgatatt
     4021 tttttgctta gctgtagcta attttttccg tctcagcctg aagacttgtg atatgtccat
     4081 ctttaagaag ctggtcaatt tgctcattcc acttgactgc ttggtgttct tgataatctc
     4141 tgtttgcaaa gtcaacgatt cctcctcccc cgattaatct ctggtagcag actccttgca
     4201 gaacaactgc caattcttct tcactcacac ccaactccag cagacgctca taaacacctc
     4261 ggatactctt ggcgtgaatg gttgaaaaga ctgtcgcacc tgtcaaacta gctctgacca
     4321 ctgcacgcgc cgtctcgctg tcacgaattt ctccgataat caagagatct ggtcgatgac
     4381 gcaaggaaag tttgattaga ttttcatagg ttaggccgat tgcttcgttc aactgcaact
     4441 gaagcatgtc gtcctgcttg atttcgacag gatcttcgat ggacataact tgctgtcctt
     4501 taaagagtga cttggacaat tcatgcatca aggtcgtctt accactccca accggaccag
     4561 caaaaagata gagtccccgt tgcctgtact gcttgcctaa ttcttcaata tcctgaaacc
     4621 aaaaatgcaa gtcctgctcc tcatcgtgca acaaacggat aaccaaactc tcatgccccc
     4681 gataatcgcc tacagtagat aaacgtagag acgccatctt ctggtcatag gcataatcac
     4741 aggaacccag ttgactacgt cttttttctc ccacattcat acccgccaca aacttaaagt
     4801 gactgataac ggctgcaaac ttttcaaaat catagctacc aattttacag cgctcgtctc
     4861 ctaccctcat atgaagctca taggcatcta acttagggac aaaataaata tcctgcgtcc
     4921 cttttttccg agctgaacga atgatttctt gtgcaatttc ttgaaccata cttacctcct
     4981 cacctatact attcgcaaag agttagaaaa ataaaaaaag caactccaaa aaagttactt
     5041 ttctctattt taatttcata cggcaagaac gattcctttc ctgactggtt tgtttttcat
     5101 agcctgagcg tagtttttcg tctgggataa cctgctcatc ctgcaaaaga gccaaagaat
     5161 ggtattgttg taaatactca tcacattcat cacaccagcg ttggtcttcc gggtcccaaa
     5221 aaatggtcat caagtcgctt ctacttttat aaagaggcga ttcttgttcc aatctaaacc
     5281 agcaagtttt gtagtatttg agagcatcat aatactggtc aaattttcta cttgctacaa
     5341 tatcttcttc ccaaccttct aagaaccacc acggttcaaa atctccgtac atttctataa
     5401 cacgatacat attcattcat tcctttgtac cgtatattat aaccaattcc gccagacaag
     5461 gaaagaaata tgctcatttc ttaatttttt gataaaaaat ccaaccatct gatggatgac
     5521 tgaatttcta tttacttatg tacaaaaata tttttactac ttaggcttct gagatatcgt
     5581 tttcgataat gaccttaatg gcatggtggt ctgctgcctt actgaagact tcgtaggctt
     5641 tttcaatttc actgagtttg aaatagtgag ttaccaattt ttctggttca atcttatgac
     5701 tttcaagtgc tttcaacaat tgtggagtcg tatttgtaga taccaaacca gttgttacat
     5761 tgatgttgcg aatccaaagt ttatctaaat cgaattcaac tggtttacca tgcacaccac
     5821 agttggcaac cgttccgtct acaccgataa tcttttgaca gaaatcaaat gtttcaggaa
     5881 tccctacagc ttcaatagcg acatctacac cgcgaccatc tgtcaaatca taaatttctt
     5941 ttatcgcttt ttcagggtct gaagagttta ccttatgagt agcaccgaat gatagggcag
     6001 tatccaaacg gttatcatcc aagtccacca taatcaattt agctggtgaa tagaattggg
     6061 ctgttaaaag agcagccaat ccaactggac ctgaaccaat aatggctacg ctgcaaccag
     6121 gttctacttt cccttttaag acaccaattt catatccagt aggcagaatg tctgacagca
     6181 taaccaaagc ttcatctgac aagtcttctg gagtatggta aagagtatta tctgcatgag
     6241 ggacacgtag atattcagcc tgcataccat caatcaagtg accgaaaatc cagccccctt
     6301 cgtcttcaca gtgggcataa attccttttt tacagtagta gcatttacca caggcacaga
     6361 cgcaagaaat caagaccttg tcaccttttt tgaagttgga aactccttcc ccaacttctt
     6421 caacaatccc aattccttcg tggccaagaa tggtaccact ttggcaagta ggaacatccc
     6481 ctttgataat atggaggtct gttccacaaa tagtggtttt tacaatacgc acaatagcat
     6541 ctgttggctt gcgaataact ggtttgtcta catcaacaaa agaagcaagt cctggtttaa
     6601 cataagtata ggctttcata aagcactcct ccgttttttt atttgtaata tttatagttc
     6661 aattgtaagc ctttttcttt gtttcttcaa gctttttttg tgattttttt aactttttat
     6721 ttaccagtaa agtaccctgt ataaaaaagc agaagctagt ctctaacttc tgccttctct
     6781 cttatgcttg ataacgtttc acaccatcta ggtaggttgc taccaattcc aaatctttat
     6841 ctaatacgat gaagtcagcg tcgtagcctt cacggatttg gccacagacg tcatcgatgt
     6901 gaacggattt agctgggttg aagctggcca tcatgactgc ttcatgcgga ttcgcaattc
     6961 cccattcgac cacattcttc aaaccatctt tgagtttgag gatagaacct gccaagttac
     7021 ctgtcgattt gaggcgtgca gttccatttg caacgacaac tgggaattct cccaacatat
     7081 aatctccgtc ttccaatccc ccagctgtca tacagtctgt gataagagcg atgttttctg
     7141 ttcctttttg tttgataaga atttcgcaag cctttggatc tacgtggtga ccatcacaga
     7201 tcaactctgc ataggtatgt ggcaattggt acatggctcc aaccataccc aattcacggt
     7261 gagtcaaccc acgcattcca ttgtaggcat gcacccaaac actcgctcca gcatcgactg
     7321 cttttttggc ttcatcaaaa gtcgcgtttg aatgtccaag agcaaccgtc acaccttcgc
     7381 ccgtaactgt acgaacaaag tcttccaccc catcacgttc tggtgcaagg gcaattttat
     7441 taagcaagcc atttgccgct ttttgccaag aatgaaactc ctcaacaccc gggtctctca
     7501 tataagttgg attttgtgcc cccttaaaag tttctgtgaa atatggacct tcataataaa
     7561 tcccacgaat cttagcacct gttgcttctt tataatggtt tccaagattt tcagtgactg
     7621 caagcaattg ctcataagtg gctgttaaag ttgtgggtaa gaaactggta acaccggtac
     7681 taagaagtcc ttcactcata gtatgcaatg taccttcaat gttgttgtcc atcacatcta
     7741 cacctgcata tccatgaata tgagtatcca caagacctgg ggcaatgcta taacctgtat
     7801 agtcaatcac ctcagcccct tcaggaatct gctctacatg ttttccaaac ttgccgtcca
     7861 caagttccaa gtaaccacct cgacgaactc cgtgtgggta gaaaaactga tccgctttaa
     7921 tatagttagg cataatgtta acctccttaa aagattgatt ctacaattta ttatgtcaat
     7981 tacattataa acctttcttt tttatttgta aatggtatag acctattttt tggagatatt
     8041 ttaaaagagc tggatttctc caactcttct cttttttaat acaagttatt ttgatttaac
     8101 cggcttatct tgagctgtct gcaaagctgt ggcaatcgta tctgcataca attttgctcc
     8161 tgcttcgata gtgctactct cactcccgaa atgaacctgg tctgttccag cccaaatttc
     8221 tggatgctct ttcgcaactt gattccaatc tgctatcgta atgtaaggtg tcttctctgc
     8281 caattctctc atataggcag cagccttctc aacgatggca taggtctctt ttgtcttatc
     8341 tccctcataa ggagtcacca aaatcatacg gtgtccctta ggaagatttt tcacgatact
     8401 gtcccagtca tccttgtaat tctcaggatt atttacccca gtcgcaatga ccaccgtctt
     8461 aggtaaaaat ttattctggc tattatttag catgatttca tttgcagtct tggttgttac
     8521 gctgacctgc gcgttaatct gtgctccagg aagagctgtc tgtagtgctg tatttgccct
     8581 taaagccact gagtcaccaa ttaacatagt gccatcagca attcccaaac tgtttgcatc
     8641 tgcccgttct gccatcacct tggtctggcc aatatttgtt gcagcttgct tcaagccatt
     8701 aacagtcaag tctgtctcaa acgctcccac ttgtggtgcc aacaaggtca ccatgcagac
     8761 aatgaaggtc aagattcctg tacctgctgc aagaattgcg tgaatataag gcaggggacg
     8821 aagagtttgt aaaataggtg tgttcttgcc tgcaatccaa ggttccaata catagaatga
     8881 cagactggca aagccataag aacaaatcag agtcagtaat acagcaagaa gatttgatgt
     8941 caactgtgag aaaatgatat agaaaggcca atggaaaaga taaaccgcat agctagtatc
     9001 cgctaaaaag ctgataatct tcggctcctg tatatgatgt gtcttttcat gtaagacacg
     9061 cgccgccaga atcatggcaa gagctgcaag actggcaagc aagaagccga taagataggc
     9121 aaaaagataa gtgaatttga caaagaaagt caaaagaact aggaaaccaa agcctcctcc
     9181 aaaaactacc aaagtctttc gtaaatccca gattttatcc aactgcttga cgagggaagt
     9241 cgtctgacga acgcctacaa tagttgctaa catacttccc aaaaagaatg gatagacatg
     9301 agttaaactg gagaaataaa cagaggaata agaggtcact agaaaactac caataaacat
     9361 ggagaagaaa ctgatcaaga aggcagcagc agataagaga aagaccatcc ccttcaactg
     9421 accatttgat ttagcttgtt tggataagaa ccaaactgcc aatccccaaa gaatatagta
     9481 gtgaacctca actgccaaac tccaattatg aacaaacaaa tgaggaatga actgagattc
     9541 ataactccca cctgttagga gttcatagaa gttggtcata aagcctaaga cgcccgcaat
     9601 ctggccacca attccagcaa catagtcttg gcgaaccaag aaagtaaaag gcatggtcac
     9661 caagaccatc aaaaccacag gtggcacaat ccgataaaag cgtcttctaa aaaatcctat
     9721 caaatcaatc tcattgttct tagaaaattc ttcaatgagt agagctgtaa tcaggaaacc
     9781 tgaaaatgtg aaaaagacat ctaccccgaa gaatcctcca ggaaagatcg tctgaaagaa
     9841 gtgatacaag agtaccaaaa gtaaacctgt aatcctaacc aaggaaaacc atttaatgcg
     9901 catacgagtt tattcttcct ttcattgtac actttattct atcaaaaaaa gaagaaaaat
     9961 cctaagagaa aacttaggat ttttagctta tatcaattcc attttagaaa ttacgtcctg
    10021 acttattata gccatatttt tccacaaaat acttacggaa ttccaagaga ttgtcatcca
    10081 tgatggcttg tcgcacttgc ttcatcaggt taagcaagaa gtaaagattg tggtagctag
    10141 tcaagcggat accaaaggtt tcatcagcct tgagcaggtg acgaaggtaa gcgcgtgtat
    10201 agttattaca tgtgtagcaa tcacactcag gatccagtgg cgtaaagtcc tcagcaaact
    10261 gggcattttt cacaaccaaa cgtccttgac tggtcataca agtcccgtta cgagcaattc
    10321 gagtcggtaa gacacagtca aacatatcca ccccacgaat gaccccatcg atcaagctat
    10381 ctggcgctcc cacacccatc agataacgag gtttattttc aggcagcagt tgagttgtaa
    10441 agtccaagac cgcattcatc tcttcatggg tttctcccac tgccaaacca ccgatagagt
    10501 agcctgagaa atccatgctg acaagatcat gagctgattg gcggcgaagg tcttcaaatc
    10561 ctgcaccttg cacaattcca aacaaacctt ggtcatgtgg acgacggtga gccttcaaac
    10621 cacgctcagc ccaacggctg gtacgctcga tcgatttctt aacgtagtca taaggttgat
    10681 aaaactgagg acattcatca aaggacatca tgatgtctga acccagatta ttctgaatag
    10741 agatggcttt ttctggggat aggaacatct tagaaccatt tagatgattt ttaaaggtta
    10801 ctccttcttc tgtgatatta cggctatctg ctaaagaata aacctgaaaa ccaccactat
    10861 ctgtcaagat aggctggtcc caattcatga acttgtggag accaccagcg cgtgcaatga
    10921 gttcatctcc agggcgaagc cagagatgat aggtgtttga taggataatt cccgaaccca
    10981 tctccttcaa ttcttcaggt gactgagttt tgacagtggc ttgtgtccca actggcataa
    11041 acataggtgt cggaaaggta ccgtggggag tgatgatttc tcctagacga gctcctgtgt
    11101 gtttttcttt cttaatcaaa cgatatttga ttggtgaatc tgacattttt tacctccgaa
    11161 gctgggaaag acagtcccag ttcatacagt gtgcccaagg acacactgta tgattttatc
    11221 aaaaaaagta ggaactgtca cgaactatgt ataagaacta tggtataata agagaatgaa
    11281 ctatccaaaa attgatttaa aaacaattcg tcaggagtca aaacattttc aggctgacac
    11341 cccccgtctc tttctcctct atatccttcc cagtatgctg gtcatcttat ctggttttct
    11401 taatccctta tctcggatcc acgggactgt tttagaacag ccatttttca gcatacttgg
    11461 ccaaatactt caagcctacc tctttcctct actagtctcc tttatcggga ctattctttt
    11521 gaccagttcc gtctatgcaa cactgacact catgaaagat tctaaaacgg agccatctgt
    11581 aaaaaacagc ctagctctct ttgatgagga gcgcttttct caaacctttt tgaccctact
    11641 tctcaaacgt ttctatctct ttttatggag tatccctaat ttacttggga tttacctcct
    11701 cttttatagt agctttttag ccaaaaaatt cgtcacccta catcctgagt ttccaaatct
    11761 agatctctca tcagttgaaa ccgagcgttt cctcatggtc tttggactct actttcttgc
    11821 aagtctcatc ttgatcattg taggaaatat cctctatatt ccacagtatt atgcctattc
    11881 acaggtggaa tttcttctct gttatagttt agacctagga caggtcccac caagacgaat
    11941 cctaaaaact agccgttcct ttatgaaggg ctacaagttc cagcgctttg tcctagattt
    12001 acagcttctt ccttggtact tcctcaattg gattaccttt ggcattgcta gtttttcact
    12061 cctaccttat atccaatgca ctaaaattat gttttaccga gcagtattgg ctcgaaaacg
    12121 tccaaaagct tgaaggtttt tcccctcaag cttttttcta tcaatgagtt tctccgccta
    12181 ccaacttgag ttcctgatct ccatgttcta tcatagcgcc gattgctgct tctatccctc
    12241 gccgaatatc cactaaactc atagttggag tagtcggtct gttcaccacc tgttccatca
    12301 tataaggaat atgcataaaa cctgccttaa catatggaaa tttcttttct accaaataga
    12361 gagcctgata catcaaatgg ctgcagacaa aagtccctgc cgtattggaa acagaggccg
    12421 gtaatccttc ttttttatag cttgaaccat cgctttaatc ggcaaactac taaagtaggc
    12481 cgaagcacca tctgggcgaa tgggacggtc aatcggttga ttatcttcgt tatcagaaat
    12541 gcgtgcatcg tcttgattaa tgaccactcg ttcaggtgtc aaactagttc ttccaccagc
    12601 ttgcccaata caaaggacaa agtcaggttg ataacgattc atctcttctt ccaatacttg
    12661 agcagatttg tgaaaaactg tcggcacctc tagccaacgg acctcagcac catggatttc
    12721 agctggtaaa cctttaatgg cctccaaagc tggattgccc ttttcccctc caaagggctc
    12781 aaaacctgtc actaatactt tcatttctaa ctcctcaaaa ccaattcaat gagacttttt
    12841 tcttaaaaac aagtataaca tatttccctt attctggatt gaaaaggatt agcgagatta
    12901 gaatcgacct tcaagtgtat ttaaagagta aaatactaat caaggccaaa atagctgatc
    12961 caccttgctt caaaataatt tttttatccg ctgttaaaga gccgtaagtc gcagcaccaa
    13021 tcacaaataa gacaaaaata gtcacaattt ctaaattctg tgagaaataa atgccataca
    13081 agagaaagac tcctagcaga gccttataaa tcccttgatt ttttaacaat aaacttactg
    13141 acggatgagc caattcttcc ttttccatat taaatacacg actagtcgca tctgattgcg
    13201 tggcaatact ttccaaataa aaaatgtaaa aatgctccaa agcaacgatc gttgttaaaa
    13261 taattgacat ctatttctcc ttaaatttct atattttcaa tacccaaaac caatttattt
    13321 aataaacggc tgagttctgt tctctcaaac tctgttaaga tactttctat ctcttcctta
    13381 accctgatat gttgcagagg gggattcacc actaactgct ccttggcata cttcgcagcc
    13441 tctaccaaca cttcccgctg attttcagga ttacgatgac gctccaccaa accttccgtt
    13501 tccaaaattt tgaaatgccg tgtcaaagca gcctgatcaa ttttcaaacg ctcctgaacc
    13561 gccatttggt tacaaggaga atgctccagc aaaaacagta aaatctgata ccgtgtcaaa
    13621 ctaatcccaa gccttttttc aaacaattgc gtactcgctt gctcagacaa gcggagttga
    13681 tacagtaaat cttgaatctc tagcatttct tcccctctct ttttattgat ttatcaatat
    13741 ttgactaatt aattgtgata taaagtaaaa tagattgcaa gaatgttgct taactcatta
    13801 caagatgata actttccatt ttccattcaa attgatactc aatgaaaatc aaaaagcaaa
    13861 ctaggaagct agtcgcaggt tgctcaaagc acagctttga agtttcagat aaaactgacg
    13921 tggtttgaag agattttcga agagtatgac aaagaaaaaa cgaacgagaa tcgctttcca
    13981 tcacgaaagc tagatctcat tcgtcaaaat gatgttatca agtcgggttt atccattcat
    14041 tgaaacgtga acgtgatcat agtgattttc tgtcacacta ccacggtctg gcattgggtt
    14101 ccaagtgtta gctggcccat atttgctatc gaatggagca tagaaacgtt gtttccagat
    14161 gatgtaacta atgccacggc tggccatatt ttgaatagca tattccgcaa tcttatcccc
    14221 taattctgaa cgttctggta ccataaagtc gatagccaaa ccttttccgt gatctccact
    14281 gtctcctgga cgataaccac taaaggatgt aatgccaaac aagttagcaa tttcttcttt
    14341 aaaggcagct gtttgtggtt gaagacctgc attttcagat tttgctactg caagtccagc
    14401 ataatcgggc gcagctggag cctcgtaagt tgttgaaatt attttcgtct cttctggttg
    14461 ataagtagaa actgctgctg tagctccatt tgatgatgct acttcttttg cttctgaact
    14521 tgttgtagtt acttccactg ctgatgcagc ttgagggctt gcttgtgttt cctgcttctc
    14581 agctggagtc gtttcctgag gagttgcttc ttcaactggg cgagttgttt cggtcgtttg
    14641 ctcctctggg acagaagtgc ccgtagatgg tgccacttct tcagaagcaa tcactgtctt
    14701 tgtaacttct gcaattggtt gagaaaggtc tgcaacctga acagtttgat catcaacggt
    14761 cacttgatta gtggtcaaat ctgctgtcgc agttgtcact tcttcactag agtctgcttg
    14821 aggtgtttgg atttcaactt ctgttacttc ttctgcttca ttgacagtcg ttgtcaaaac
    14881 agtttctggg aaaatcaagt ccatattagt gattttgttc agattcgcaa gcactgtgac
    14941 atctacaccc aaggcttctg caatggtgct caaagtatca ccatactgta cggtataact
    15001 tgttttgttg tccgttttag tcaaatcgtt ttggatttgc tcaacactac gtgcagtcca
    15061 aagaacttct tctgcttgag ttgccaatac tggggcaaat gacaaggcta ctgttgacgc
    15121 taataacatt cttttcttca ttctttcaaa ttcctttcaa atgagtacct gtctatcata
    15181 acacaaaaaa tgtagaaaaa aagccctctc gggcctattt aacagaactg tctattcctt
    15241 gtaacaaact aggttacttg aaatagtttg ttaggtctct gtcacaaaac tgacacaatc
    15301 tttttatcac ttagtctcaa aaatacggga aatatctgct aacgcttgaa tcctgtgatt
    15361 cccttcataa gtagactcta aaaagttgat gctttgaatc ccactattct gggcaaattc
    15421 cacatccaga gtccgatccc ctatataata agtattatca gaattcaact gatacttatc
    15481 tagcagatag gtagccgctt ctggacttgg cttctggact tggcttccgc acaaagccac
    15541 tctgactggt taaaatctct ttaaaatagg attccacccc caagtccttg agaatggtaa
    15601 aagcgttgtt ccccttatga gtatatataa actgctgaat tcctgattcg tctgcccaag
    15661 ctagcacctc acgcgcacct ggcatcaaaa ctacctgagc attcttctca gccagactct
    15721 gggcacgcac ctgatttagc acctcaacat ccagatttct atcttctgcc acccgcacaa
    15781 gcaaatcttg caccgaatac ttgaagataa actctctcac cttctcctta tcataaggaa
    15841 tagaaaactg agcaaaagtc tcctcaatcc ctgataaaat cgcttcgtaa gagtccaata
    15901 aagtcccgtc taaatcccaa ataaaagctg ttttttgcat ttcctatcct ttcaagctca
    15961 tatagcgctg gtaacgatag cgtagaaata accagcgaaa accattatcc aagagagacc
    16021 ctgcccaaat accaggcaag ccccaaccaa gcacaatccc catcagatat cctgtcccaa
    16081 tgcggataca ccacattcct atacttgtcg cataaaaagg gaggcgtgca tttcctaatc
    16141 cctgccagac tgccgtatag atgactgttc ctgtcgtcat aggggtccca agtagtgaaa
    16201 acagtgtcac tagaacacta gcctccaccg ctagagaatc agtcgtatag agatgagtta
    16261 atggtacacc caagacatat atactaaagg acaggggcaa catgaggaac agagaaagcc
    16321 aaaaggtttg tttactcaaa ctagcaactc ttttccaatc atcctctcca actgctcggg
    16381 ccaacagcat gaccgttgcc gtagcgacgc caaaggcagg catatagtta aactgggtca
    16441 agacttctcc gattgcattc ccagcaactg cctccgtccc aaaagaaacg accaaggcaa
    16501 tgatcactac atctccagcc ctcatcataa gtcgctctcc agctgctggt aaagccaagg
    16561 tcaacagttc cttatctaaa ccaaaagttg gcttcccata aggcagtttt aattgtgacc
    16621 acaaaatcac aagaccaacc aaacgagaca caattgtccc ccaagcaaca ccagctatcc
    16681 ccatatccag aacaaaaata gctagacttg aaaaaagaat attcaaggca ttggataaaa
    16741 aactaacata gagaggcaga cgtggattat gcgttgcacg aatcaaggct cctagactag
    16801 tcattaaacc taagagaaca atcgatccgc ctaccaaaga tagatacagt ccaccactct
    16861 cagctacatc cctctccgtc cccaaaagtc ctatcatctc tttcccagcg aagatggaca
    16921 aaaatcctaa aaggaaactt aatagtaagg taatcttcaa cgcctcagtc acatgatagg
    16981 ccaacttcga ctggtctttc tgccctatgc tttttgaaat aacactggaa atagcagctc
    17041 ccagagcgat gaaaatcgcc tgataaatgg tgataatatt accagctact gaaacccctg
    17101 aaatagctat caatcctaaa tgagcaacca aataactgtc caccattccc attagcatct
    17161 gcaaaaagtt ttcacccata gctggcaatg caatattaag aatgtcttta tttttcttaa
    17221 acaatctctc ctcctgatga aaagaaactc agttggtttc ccaaccgagt ttgctccctc
    17281 tgtcttaaag tcctaaataa gcctcaaccg ctgcttgcat gtcagcagct gccactgttg
    17341 tcttgtgacg aattggagct atttcaagcc catcaactgc tggtggcact gcaacgcctg
    17401 agatttcatg taattgagcc aaggcttcaa agtctgttaa acctgctttt ccagttacag
    17461 cttctactgc aactactggg aacttgtatg gactagctgt tgaagcaatc actgtcttag
    17521 ttacatctcc agtggccgat tggtattttt tataaactgc tgaagcaaca gctgtatgag
    17581 ggtcctcgat ataagaatct aactcacaaa cacgcttgat ctctgctgcc gtttcttcct
    17641 cagtcgcata ttcagctgca aagaggtcca aaatctctgc atcaaagtct gtcaacttat
    17701 attgtccttg cgtgttcaag gcattcataa gttcagttgt cttttcagca ttatttccca
    17761 aaagatggaa aatcaagcgc tccaagtttg aagataccaa gatatccata gatgggctgg
    17821 ttgttacctt aaactcacgt tttttgtcat agacacgtgt tttaaagaag tctgtcaaaa
    17881 cattgttgtc atttgaagca cagattaatt taccaactgg caaaccaatt tgtttggcat
    17941 aaaaggcagc caagatattt ccaaagtttc ctgttggtac tgtgaagtta accttttcac
    18001 cagctacaat ttcaccagtc ttaaccaatt gagcgtaagc ataaacataa taaacaattt
    18061 gtggcaccag acgaccaatg ttcatagagt tagctgatga aaattgcaac ttgttggtag
    18121 tcaatttttc acgaagagcc acgtcgttaa acatgtgctt cacatttgtt tgcgcatcgt
    18181 caaagttacc atcaatagca ataacatgag tattgtcgcc agtctgagtg gtcatttgta
    18241 actcttgaat cttgctgaca ccatcctttg gataaaagac gataatctca gtaccaggca
    18301 cattcgcaaa ccccgccata gcagctttcc ccgtgtcacc agatgtcgct gtcaagataa
    18361 caatcttgtt ctccaaacca tgtttcttag cagcagtcgt cataaagtat ggcaaaatag
    18421 acaaggccat atccttaaag gcaatcgttg aaccatggaa aagttccaaa ttgtattgcc
    18481 catctaattt cactaatggt gcaatagctg gagtatcaaa tttgctatcg taggcattgt
    18541 tgatacagta gtccaactcc tcaactgtaa agtcatctaa aaatgctgac aaaactagct
    18601 tagcaacttc ctggtaagaa gcatctttca atttgtcaaa gttcaaatct acctttggat
    18661 aagtaaccgg tgtaaacaaa ccgccgtccg tcgccaaacc ttgcaaaatt gcttggctgg
    18721 cagttactgt attgttggca tcacgcgttg attgataaac taatgtcatt actctctatc
    18781 ctttatctat agtctcgtcc attatatcat gatttttcag aaaattctcc ctttataaga
    18841 gaaattatag gctcaattct tctctcaaag gctgtaaata ggtcatttct tccttatttc
    18901 tcaccactag tccctcctca gctagtagga gtaagtcttt ggaaaattca ataatcgtag
    18961 tttcttcctc atctgtaaga tttttcttag aaaattgtct ccttaaagac ttgtaatcat
    19021 aaccaaatac tttaaagaaa ggtgctgttt ctaagtaagc ttctaacttg tctaaattaa
    19081 ccaataatcc caagtgaaaa gctgcagaag caaaagtcct atcaagtggc tgtgtacaca
    19141 cactacgaaa ctcaactgtt cctcgagtcg ttaaatcttg gtactggtaa ctacgatgag
    19201 tttcaaaatc cttctcttgg gggtaaataa taacctcatc cccattcaga gcaaatgctt
    19261 ggatttcgga cgtagccaaa tagtccccag cctgaatagg ataaaaataa taggtctgcc
    19321 catcacgttc cgcagtaaaa atcgcagaat gatttagata gtcaaaaaaa tcagcttcat
    19381 cattaaggag tctagcattg accccaacat tctctggata gataccatgc atagattctt
    19441 cccagaaaat atcccttgaa attttcgtat cccaatccgc acccgaaaat tcagagtttg
    19501 caaataaata agccttagcc gcttcaattt gagtaaaagc attaatcacc cgtaagtagt
    19561 tggtttttga aatatccagc tgaacctggc tcccacagat aaaagtacca tattcaggga
    19621 aatgatgtaa atctgattta ataatatttc tactcaaatt caaataatcc atcaacatct
    19681 gatagcgtgg ataagccact ggacaattct catttttatc ccagttggga tggataccac
    19741 agccaacaat agcatgattt gattcagcta actttctctg aattacattc atataattat
    19801 tgaaacgatt ttcgacctct tgaatcgttt cagccttacc aaatgcaaac tcaatcgttg
    19861 tataggaaac ttcaaataaa atagcatcct gacttatcgg atctactaac tggatcagat
    19921 tgccaaaatc atctaccttt gctacggtga gatccaaagt agaaactaaa taatgaaata
    19981 gatccttcat aacttcaaca tctgtagcat ccccttctaa acttgcaaca ggatactcca
    20041 actcaattcc gacaaacaat tcaggatttt ctttaatatt tttcaaatac cgatgtttta
    20101 ataaatcgat agaacaagac atactcccct acactttctt aatctaaata aaatttgaat
    20161 aactataatt ataccaaaaa taatataaaa aaggaacgaa gaataacaac gttcctaaca
    20221 ctatactata ccggcggccg gggtcgaacc ggcacgtcct tgcggacact ggattttgag
    20281 tccagcgcgt ctgccaattc cgccacgccg gcaaatagta actggggtag ctggattcga
    20341 accaacgcat gagggagtca aagtcccttg ccttaccgct tggctatacc ccaatataaa
    20401 ataggcgagt gatggggatc gaacccacgc atgccagagc cacaatctgg tgtgttaacc
    20461 acttcaccac acccgccata attctattaa cacgggcagt aggaattgaa cccacactga
    20521 aggttttgga gaccttagtt ctacctttaa actatgcccg taaaatggaa ggggagggat
    20581 tcgaaccccc gaacccgaag gagcggattt acagtccgcc gcgtttagcc tcttcgctac
    20641 ccttccaaaa tatataaatg gcgcgagacg gaatcgaacc gccgacacat ggagcttcaa
    20701 tccattgctc taccaactga gctaccgagc cttattgcgg gagcaggatt tgaacctacg
    20761 accttcgggt tatgagcccg acgagctacc gagctgctcc atcccgcgtt aatataaaag
    20821 gaggatgtgg gattcgaacc cacgcacgct tttacacgcc tgacggtttt caagaccgtt
    20881 cccttcagcc ggacttgggt aatcctccaa aatagtttat acgggaacaa gcccgtgtcc
    20941 tcttagtgaa cagataatat tccaatcccc tagtaatgga ctaaacacta tgggcacgag
    21001 tggactcgaa ccaccgacct cacgcttatc aggcgtgcgc tctaaccacc tgagctacgc
    21061 gcccaagtca aaaacttggt acaaagaaca aagttcaaag cgggtgacga gaatcgaact
    21121 cgcgacaaca gcttggaagg ctgtagtttt accactaaac tacacccgct aaa
//
LOCUS       DAVHSL010000036        21081 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000036 DAVHSL010000000
VERSION     DAVHSL010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.037"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(380..2107)
                     /gene="ezrA"
                     /locus_tag="VVR39_001414"
     CDS             complement(380..2107)
                     /gene="ezrA"
                     /locus_tag="VVR39_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU6030884.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2189..4135)
                     /gene="gyrB"
                     /locus_tag="VVR39_001415"
     CDS             complement(2189..4135)
                     /gene="gyrB"
                     /locus_tag="VVR39_001415"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU6030885.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4150..4713)
                     /locus_tag="VVR39_001416"
     CDS             complement(4150..4713)
                     /locus_tag="VVR39_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6030886.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4798..5352)
                     /locus_tag="VVR39_001417"
     CDS             complement(4798..5352)
                     /locus_tag="VVR39_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU6030887.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5363..6586)
                     /locus_tag="VVR39_001418"
     CDS             complement(5363..6586)
                     /locus_tag="VVR39_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6030888.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6623..9073)
                     /locus_tag="VVR39_001419"
     CDS             complement(6623..9073)
                     /locus_tag="VVR39_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU6030889.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYFVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9273..10202)
                     /locus_tag="VVR39_001420"
     CDS             complement(9273..10202)
                     /locus_tag="VVR39_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6030890.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10342..10629
                     /locus_tag="VVR39_001421"
     CDS             10342..10629
                     /locus_tag="VVR39_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU6030891.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAVAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10663..11997)
                     /gene="ciaH"
                     /locus_tag="VVR39_001422"
     CDS             complement(10663..11997)
                     /gene="ciaH"
                     /locus_tag="VVR39_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU6030892.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11987..12661)
                     /gene="ciaR"
                     /locus_tag="VVR39_001423"
     CDS             complement(11987..12661)
                     /gene="ciaR"
                     /locus_tag="VVR39_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU6030893.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12770..15316)
                     /locus_tag="VVR39_001424"
     CDS             complement(12770..15316)
                     /locus_tag="VVR39_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU6030894.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15439..15879)
                     /locus_tag="VVR39_001425"
     CDS             complement(15439..15879)
                     /locus_tag="VVR39_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU6030895.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15854..16501)
                     /locus_tag="VVR39_001426"
     CDS             complement(15854..16501)
                     /locus_tag="VVR39_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU6030896.1"
                     /translation="MKNQLALSGEKILEKIYPLFGYRGTRRLLACLDEFQAEAHVITE
                     VYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIELPSAYFDLSSILETGI
                     SKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKARKNKINFAVAGYLNTS
                     FIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKKLQRSTHDTARNVE"
     gene            complement(16543..17271)
                     /locus_tag="VVR39_001427"
     CDS             complement(16543..17271)
                     /locus_tag="VVR39_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030897.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17279..17758)
                     /locus_tag="VVR39_001428"
     CDS             complement(17279..17758)
                     /locus_tag="VVR39_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6030898.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(17769..18467)
                     /locus_tag="VVR39_001429"
     CDS             complement(17769..18467)
                     /locus_tag="VVR39_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU6030899.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     RFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18460..18726)
                     /locus_tag="VVR39_001430"
     CDS             complement(18460..18726)
                     /locus_tag="VVR39_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU6030900.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18792..19718)
                     /locus_tag="VVR39_001431"
     CDS             complement(18792..19718)
                     /locus_tag="VVR39_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU6030901.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19793..20608)
                     /locus_tag="VVR39_001432"
     CDS             complement(19793..20608)
                     /locus_tag="VVR39_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030902.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20612..20932)
                     /locus_tag="VVR39_001433"
     CDS             complement(20612..20932)
                     /locus_tag="VVR39_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6030903.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6381 a         4626 c         3689 g         6385 t
ORIGIN      
        1 caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg agatttttca
       61 atagacttcg ttattggacg gttaccaagt tactcaaagt acagatttga agctgcagat
      121 aagactgacg aaatcacttt aatactaaat gaaaatcaaa aagcaaacta agaagctagc
      181 ctcaggctgt acttgagtac ggtaaggcga cgctgacgtg atttgaagag attttcgaag
      241 agtataaaac actgttttga ggtggtggat aaatcggctg agtaaaaact caatctcagg
      301 agaaaatgaa gtaaatctcc ccacaactat agaaaaagat ttgattctgc tcctcacaca
      361 ataaaatctt tttcttttat taaaaacgaa tcgtttcacg tgttttctca tatgaggtaa
      421 caaagcgatt ggttacacca ggctctgcca cttccaatgc ttgagaaatc ttgtcaaatg
      481 aagcgtgata atcaaattct ttttcaaaaa tatctaaagc ttcgttaaat gcttcttgaa
      541 tgcgttcatc aaatgagcga tagcggttag aatattgcaa gagttgctct gtcaaagttg
      601 catattgtac aatattataa gtttccgttt ctaaagcttc catatcattc gttgcaattt
      661 caagaactcg ggtaacagat tcaatgttaa tcattttttg ttctaactca accattaaat
      721 cctcggtatt attgcttgcc gtaaagaata acttcaagaa agtttgtgga atacctggca
      781 gattgcgttt ttccatgtat cgcttgatag tatggagacg attgacataa acattggcct
      841 tttgacgtgc attaatatca tctttctcaa tttgtgtcag gcgctcacta actgaaattt
      901 gctcatcttc aatatctttt agttgagttt gtaaatcctc aagattttct tcaagaactg
      961 aataagcttg ggttggttct tcttgatttg aagttacctc aacaatagct gcctcaaaac
     1021 tctctaattc tgtctgaata cgacgaacat ggcttgcagc tgtctcagga agtaaatagg
     1081 tcttgttcaa acgtgcaata tcttctccca ataaagtatt attctctttc atatgttgaa
     1141 ggtaagttgg aagagttgca agtagatttt ccactacttt ctgagcagca atttctcgag
     1201 taaaaatatc atacaaggca ttgatttcct cttgtgcctg tccattctca tattcggcat
     1261 tatccaattc caactgacga atattctctt ggtttttctt gaatgcttca taaagcaagt
     1321 ggaaacgcgc ttcaatatcc gtttcaacaa aatgataatt agcatcaatt agtttacgat
     1381 aaccggcttc caaatcctgt aattgatctg gcaattctgt agaaagcgtc gtaaccaagg
     1441 ctggaacacg atccacaata tgacttaagg ccaaaatgtg attttctgta ttatccaaaa
     1501 tcactgcggc ttccacaggg tcacccgatg aattcaaggt tacaaattgt gaaaattcag
     1561 attggatatt ttctaattgt ttttcaattt catccaaggc ttgaccatac tgttctgaat
     1621 tttcagcaac tctatgctga agttcctcaa ataaatccaa agcatgaaga acacgaccac
     1681 tatttttaga ttcttgcttc tctaagtctg ccaaagcatt gcgaattgcc gcaatatctt
     1741 cttcaatcaa agtaatttga ctctcaattt ggtcaatttg atgactggcc ttgagaaaac
     1801 gaaatgaatg gttatagcct tctgcttcaa agagattatt ttcaatatcg gcaaaagagt
     1861 tgagagataa atcgacccat ttttgattcc attcacggaa agccacttga ctttgtccaa
     1921 tcaagtgcat attttttaca gcttctactt catcatttac tggaagattg tatagttctt
     1981 cttttctttc ttctagcgcc tctaatctcc cctcgtttcg cttacgtaga aagattgcca
     2041 ctacataagc cagaactaaa atgactgcaa ttgcaaccat taaataaatt agttgtccat
     2101 tagacatatc aaactccttt tttacttgaa acaatcgtaa cgattatatc atatttttta
     2161 gaccaaggga actacttctc cctatttttt agacatcaag tgtactatag acagcatttt
     2221 cttcgataaa ctcacgacga ggctctactc gatcccccat caacatatca aagattttat
     2281 ctgcttctgc agcatcatct acagaaactc tagccatcaa gcgatgttcg ggatccatgg
     2341 ttgtttccca cagctgatga tcgtccattt cacctagccc cttataacgc tgaatagtcg
     2401 gtttggtacg accttcacta taacgggcta aagcttcttg gagtttgatt tcttgatctg
     2461 cacccggctg gatatattct ttaatctcgc ttccaacctt gacaccatag attggtggtt
     2521 gggcaatata aacataacca gcttctagga ttggtttcat ataacgataa atcaaggtta
     2581 aaagaagggt acgaatatgg gctccatcga catcggcatc ggtcatcaaa acgagttttt
     2641 ggtaacgggc tttcgaaaca tcaaattctg cgccaaatcc tgttcccatg gctgtgaaaa
     2701 gactacgaat ttcttcgtta gctagaatct tatccatact tgctttttca acgttcaaaa
     2761 tcttaccgcg aattggaagg atagcctgaa actcacggtt acgaccagat ttggctgatc
     2821 caccagctga gtctccttcg acgatgaaga gttctgtttc agcagggtta ttagaagaac
     2881 agtctgctag tttccctgga aggttggaaa tttccaaacc agatttttta cgtgtgactt
     2941 cacgcgcacg cttggcagcc acacgagcct tggcagctaa aatccctttt tccacgatac
     3001 gtttggcaat ctgtggattt tccatgagga aatcggagaa ggcttcactg aagaggcgat
     3061 tggtaatctt gaccacttcg ctatttccca atttggtctt ggtttgtcct tcaaactgtg
     3121 gatttgggtg tttaactgag ataactgcag ttaatccttc gcgaacatct tcccctgtta
     3181 aattatcttc attgtctttc agtaacttat tcttacgagc ataatcattg ataacacgag
     3241 tcagtgccgt acggaaacct tgttcatgcg ttccaccttc atgggtatga atattattgg
     3301 cgaaactcat gacattttca tggtaacctg ttgtgtactg catggctacc tcaactgtaa
     3361 tatcatccat ctcaccgtct gtatagattg gtgtatcaaa gattacatcc ttgttctcgt
     3421 tgatatattc aacgtaacta gcaatcccac cttcataatg ataatgcttg gtttgttcca
     3481 aaccttggcg cttatcagtg atagaaattt gaagaccgcg atttagaaag gccaactctt
     3541 gaatccgttt atttaattta tcaaaatcaa agattgttgt ttcagtgaaa atttctgggt
     3601 ccggtgtgaa gtgaaccgtt gttccagttc tatctgtatc cccaaccacc tcaaggtctg
     3661 caacaacatg accacgacgg tattcttggt aatgaatctt accgttttta tggacatgaa
     3721 cgtctaattg agtggaaagg gcattaacta ctgacgaccc caccccgtga agaccacctg
     3781 aaaccttgta tccaccaccg ccgaactttc ctccagcatg aaggactgta aagacggtct
     3841 caacagcagg acggcctgtt ttttcctgaa tatcgactgg gataccacgc ccatcatcca
     3901 caacagtaat cgaatcatct ggctcaataa aaacttgaat atggctggca aatcctgcca
     3961 aggcctcgtc aattgagtta tcaacaattt cccagactag atggtgaaga ccttcttttg
     4021 aggttgatcc aatgtacatc cctggacgca tacgaacagc ctctaagccc tctaaaactt
     4081 gaatttgact ggcatcataa tcctgtgcct gcagattttt gatttcttct gtcatcttat
     4141 tcctttttct tatatgtcta atacttgtct taaattcacg atactggtaa acaagtgggt
     4201 atcaagtcct gcagcttgac ctgcttcgat atcaatcggc cgatcaccaa tgacaagacc
     4261 agagctaatc tgatactttt ctcttaaata aagcatggat tcgggatttg gctttctctt
     4321 aaagcctgag ctagaagtca ccacttctgt aaaataagct gctatagagg ttttttctaa
     4381 aatttccaaa acctgatcat ttcgatgaga gaccaaaaaa tgacggccac cttgatttaa
     4441 aatgtcttcc aataggtcag aaactccttc aaataaaatc gggtgttcaa gctctctggc
     4501 ttcattttcc ttgtactttt ctaaaaaatt ctctaaattg ggagcgaatg tctcaatcgc
     4561 aaaaggagta gaaaccttta aagcttgata gacactgtca tggtcttgtg tgataccata
     4621 cagtgccaat gtttcaacaa atgcagctgt tgaagtttca taattatcca gtaaagttcc
     4681 acctaaatcc cagatgtaat cgtgatattt catacccttc attatagcat ttttttatga
     4741 aaaaagcgat gatttccctg agttttccac ataaaaaacg agagaataac tcccgtttta
     4801 ctgattttta ccaaagacat ctcgatagag cattcctgtt cgtaaactct ctgcgtcccc
     4861 tcctagttgc tccaccaact cgtaggcaaa ggcaagggct gttgaaggac cccgactggt
     4921 tgtcaactga ccatctacca ctactgtttc cttgacgtag tgaccatcaa ggatttgctc
     4981 ttgaacgccg tcataacaag tgtatcgctt atttttcaat atctctgctt gattgagggc
     5041 aattggtgcc gcacaaatgg ctgctagttt cttcccttct tgctcgaagc tttgcaattc
     5101 ttgaatcaag gtctgattat cacgtaaatg tgcagaacca ggcatacctc caggaagaac
     5161 aatcatatca tagtctgata aatctccatc aaagacatga tctgctctta cttggattgc
     5221 atgcgaaccc gttacttgct cttcaaaacc aaccatatca catgtgatat tggctcgacg
     5281 caagacatct acaactgtca aggcttcaat ttcttcaaag ccctgagcta acataactgc
     5341 tacttttacc atgattttct ccttatttaa tttgttttaa tacaaccttt ttccgtttga
     5401 atgggacttt tccgctcttt tcttcagcta gattagtctg gtaactcatc gataaaagca
     5461 aaccaacacc aatcagatta ctgataatag ctgatccccc ttgcgaaatg aaaggcaagg
     5521 gaatccccgt caaaggaagt agtccagtca cagcaccgat attctcaaag atgtggaaga
     5581 gcaacatcat aatcaaacct gtggaaatat aagtgtagaa ctggttattt gatttaagag
     5641 taatcttcaa catacggtaa atcaacatga gatagagggc aataaccagg acagagccaa
     5701 taaagccaaa atcttctgca ataaccgtaa aaatcatatc tgactctcga actgggataa
     5761 gcagattcga agcattaaat ccctgaccaa ataagccacc actcccaatg gcaatctgcc
     5821 cttgagcctg ctggtaagtc gttgtttggg caaactcaaa gggattgagc caagccaaaa
     5881 tccgattgat ttggtaggtc ggcattccaa tctggtgaag aaaagctcgt ccgtccttgc
     5941 taataaagat agctaagaaa ccagcaactc ctgttacagc agtcacaaat actgggataa
     6001 taattttcca agaaacccct gataataaaa cgattcctga gaaaatggct acaaaaacca
     6061 aagccgtccc caagtcactt tgaagtgcta aaagaactag gactggaatg gtaaagagaa
     6121 tcatccagaa aattaacaaa aagtccagcg aaaccgtgcg tctccattcc ttatgtttct
     6181 ttgtaaattg gacaatgaca cgagccaaca tgaggatata ggatatcttc ataaattctg
     6241 acggttgaaa tagggtaatt ccatttattg atacccagtt tttggcaccc gttgatgcaa
     6301 ctaagcttgg attataaaat acaatcggca agatcataag tcccaagcct aaaatatata
     6361 gaaagggggt caccttccaa agaaattctg tattaaagag catgaccaca aaaccaatca
     6421 caagccccaa ggcaatccag gcgacctgct gccctaaaat gggcagaata ttattgggat
     6481 aatcatgact aacggctata tagatagcca ccacaccgat gaccagtaga aaaaatactg
     6541 gcaagagcaa actgtaatcg actcttgagt cgagagaacg tttcatatat actaacctta
     6601 tactttcata caatactatt tatcaaagtt cattaaaaaa tctatcaata gcctcgtcaa
     6661 cttcggatcg agagatggtt ttaacagtcg cttcttctgc tagagatgct actatttgtt
     6721 tgccgtatcg ttttccgacg attctcctat ccaaaataag agttaaggaa cgttggtatt
     6781 cacgtctcat acttcttccc aaagcctgtt ttaaacgaat aatggccatt ggcaattgat
     6841 aatcataaaa ggcatttttc ccttcttgat tcagttcttg attaatcttt ttcgtcaagg
     6901 gttcttgagg attttggaaa ggaagcctcg gtacaacttg aatcacaaaa ggatggcttg
     6961 aaaaatcaac tccctcccag aaacttgctg caccaagcaa gatttgttgt tcaccttttt
     7021 caaagcgttt ctttagctga tgaacatccc catttttata ctgggccaag tggctaactg
     7081 taagtaaatc cgatactgct agaagcatgt ctttagcggt aaagagaacc aaaatcggtt
     7141 gctggaaagc ttgaatttcc actagtaaag cagctacctc tctggcatag acttctaagg
     7201 aggtttctgt taccagaggg aaatctttga ccataaccac ttcttgttcc tgttttcccc
     7261 gagattcaat cttgacaaat ttagcttcag gatagcctaa aaggtctgcc aaagaaaccc
     7321 tctgactaat ctcaagagta gccgatactc ccaggacttg gcaactctca ggaagtaaag
     7381 aggacagaag agtacggcct gattttgtag aagaaatctg aattttcttt tgactcgttt
     7441 cagttacttc aagccagtaa tcaccttcag ctgtaaaata gcgaaccagc tcatcaaagc
     7501 cttctacttc taattctgaa aaatactgat ggagattgtc cagagaatct aagatatttt
     7561 tcctagattt accagactga aattgttcta tcaagtagag acactcaaag cgaatacttt
     7621 ctagtatccg ttgttgaacc ctgttttctt ctcctactaa agccttatca attaaatcga
     7681 taatagattg tatatcgtag gtctcttgaa gcagattttc tagagctaac aaaatctttt
     7741 ggacttcatc aataatcagt aaacggtcac tgacaaattc aggattatct tcaagtctgg
     7801 tcacgaaata ggcatgatta gtcactaaaa gcttgcaagt ctctgccctt tcttgactac
     7861 gtttccaaaa atcttccgtc acaaataagc tctgggatga taaattccca tcatgacgaa
     7921 ggtctgctag aaaatgttgg taacggtaga gttgcccgat ttcatccaaa tctcctgtct
     7981 ctgtctcagt aagccagacc aagacttgca ttttaaagcg tctaaataag cgattttcat
     8041 cattttcctg caaggaatga taaaaggcat ccaacttcag ataattttgt ggtcccttta
     8101 agctatgaat atctgtatgg aacacttcct tgagacgttt accttcttct tccatgattt
     8161 gattttgaag aatctttgtc ggaacactaa gaacaatttg tcgctctttg gattgagata
     8221 aagcgggtaa gagatagcca taggttttcc caatccctgt cggcgcttga atcagaaaga
     8281 caggttcatc tttcaatagc aagccaacct ctttagcaaa actttcttgt tcctccctca
     8341 cttcaaggtt caacagagaa atatttttag aaaagtcttg agatagtttt cgtagctcca
     8401 gagaagctgc cgttttctta aaatacagac cttgaacttg gaccaagtct ggagaactca
     8461 ggatagattg gttgcgataa gtttcctcaa taaccaggta ggactcatat aggagagcgt
     8521 cagccatttc cagcaagcgt tccaagagac ctttaggaag ctgggtcatc ttttcccgta
     8581 aaaaaagaag taattctgct gtagcttggg catctgaaag ggctgtgtgt gcgtgtttaa
     8641 gaggaattcc taattctcga cacaaaatcg gcaagctata tttttccagt tcagggaaaa
     8701 agacctgggc caattcgacc gtatcaacac gagggtttct tagctcatag ccttcaaaaa
     8761 ataaattttc cgccaagaga ttagcatcaa actgaacatt atgggctaca aaaatcccat
     8821 cctccaccaa gtcaaatatt tttctggcaa cttgcgaaaa atcaggtgct tgcgccagac
     8881 gttggtctgt caatcctgtc agttctttga tatgagcatc caagggttca tgtggattga
     8941 catccgtcgt atagtgatcg acgatttctc cgtcctcaat cacgacaatt cccacttgga
     9001 taattttagc cttactacct gtgctagttg cctctaaatc caccacaaca tagcgattac
     9061 caatcgtttt cattataaaa aattatacca aaaaaagggc catttggcac ctgcaaacat
     9121 aggataattt tcaaactcaa gaacactact tttcttaaaa atcccatcga atagagcatt
     9181 ctagcctgct gatttttgta aaatagtgaa gaaatacgaa aaattgagag aagaaatgtt
     9241 tgcatcttcc ttctctcaac gaatcatgta ttttatctaa ccatgtcagg atcgtagtca
     9301 taaaatcctg tatcaaggaa acggttttta gggtgaagtt tacgaacttc ttcatccagc
     9361 aagaaggctt gatcatggct aaagttgccc tcttgaatca aattacgcgc ttggataaag
     9421 agttttgcaa tctcaacaaa gttctgacca ggagtgtaga gcccttctag tttccagcga
     9481 gtaaagccat gctccaccaa ttctgttaat ttgatcatca aatcaaggtc attgttggca
     9541 aagatatggg tcccatgatt atcttcaaaa atggaatagt ggctctctgg atcacttggc
     9601 tcagccaaga agaggtcacg tttatgcgtc ttttcatcat cgatatgtgt aaagttatag
     9661 tagttttgca agagtggacg tttagaatga tggatgacgc tagcaccgta aaccaaaact
     9721 tcagcaggaa tttccaaaat ctctggcatt ttgaaaagtt cagctgatgg aatttcacgc
     9781 gccaaaacag cctcagatgc gccagccttt tgtccccaga agttaatctg acgactgcta
     9841 gttaccatgg ttgaagcatc gtagatggtc ttaaatgaat aaccatcgcg gttaactacg
     9901 taaaagacgc ctgcatcccc aatcgtaata tagtctgtct tgatttcttc caagaagtct
     9961 aagaaaggct tgatacggtc catcatatct tggtgcatga gagcattgac cgcaacgagc
    10021 aattccttac cagcatcatg aaccaactta gcgatttcac gtaattggtc ataactaaag
    10081 gtcgttggca gacgaaggcc aaaatctttc tcaccgacat agatacggtc tacgccagct
    10141 tcgagtagtt gttcaacttg ttcaatactt tcagcagttg ctgtaatgac aatcttttcc
    10201 ataagaaaaa ttataccaca tttctccaaa atcatccatg ctttgaaaat gaaaagggac
    10261 tttattcttt ttgtaacctt tctgtaataa ttctctgccg aaaaaatgat aaaataggta
    10321 tgtactgtta aggagagaat tatgcccgta agaaaattac aatcctatga ggtagactat
    10381 caagaagaat taaaccagca gcttcctcat taccaagctt atacacctga agcgcaatct
    10441 gatgccaatc tcaaggaaat cctatttttt attaatatcg ctgttttttg tatctgtatt
    10501 gctatcttta gttttatctt tttagcatta aaattatcaa ctgctcttgc ctttgccgta
    10561 gcaatcggat tcagcttact tgttttaaaa gttcaacggt ctattatcaa acgaaaacgt
    10621 agaagataaa tccaaaatat cgccccaatt ggagcgatat ttttattttt tctttttaga
    10681 tggtgtctga atggcaatct tcacttcaaa gattgttccc ttgggtttat tatctttgac
    10741 agtaacagtt ccttttagag catctacaat ttgcttggct agggataatc ctaaaccaaa
    10801 accacctttt tgccgggttc tagccttgtc tactcgataa aaacggtcaa aaattttctt
    10861 tttatcttct gtcgaaatac cgattccatt atcagaaaca agtaaataaa gattgcgatc
    10921 ggtcgccgag ataagaaaat caatttcacc atcctcctca gtatacttga cggcattatc
    10981 gaaaagaatg gtcatcagtt gtttcagaag aagctgatct gtgacaattg ttcgatggat
    11041 acgattttca aaacggaaga cacgattatt ttccgaagca atcatctcat agtttgtgaa
    11101 agttgtatta aaaaagctag ttggaacttc tgcaagctcc ggcttaatcc catcatctct
    11161 ccgagctaag ttcagcaagc ttgtcgttaa aaaacgcata tttcggactt cttccaaact
    11221 cgatgcaatg ctttcgctca catccataat ggtagcttct ggcttacgaa aaagggtctc
    11281 taagcgattt tgcaaaactg cgagtggagt tcgtaactca tgactggcat tttccacaaa
    11341 agactgttgc ttctgcatac tctcaagcag gggcctaaca ctgaccctag ctagatagag
    11401 actggcaagt aaagacaaaa tccagaaact agccatcacg accacaatca attgctcatg
    11461 cttttgacta gcctgctcca actgactggt attaatcaag acagcagcat acttgatatt
    11521 ggttgaaacc gaactaatat tggtctccat caaaatcaca cgatagattt cttcctgccc
    11581 atagctatta aaaacctgaa tctggtagat atgtcctagt tctttctttt ctaacttaat
    11641 cttatccaag cccaaaaatc gatttccaga aagaagttga gtaaagtctt tatcaaagag
    11701 aatgacttcc gtattggaac tgacattagg ttttatttct actttactag cgtccgccct
    11761 agcattttct aaatctttaa tctcttctgt tgccctattt atagccagct gaataactgc
    11821 ttgaggattt tcactcagtc catgaagctt atcgtccacc gaagtataaa gactcgaatg
    11881 catgacttgt aaaataatca gagtcattgt agaaaaaatc agggtgaaga caccgaagtt
    11941 gcggataaaa taactaaagt catccgcata ccatgttttt ttaagtttac tgaacatctt
    12001 ttaaaagata cccaacacta cgcaaagttt gcaaattctc tgcaaaagtg gttcccttta
    12061 atttcttacg gacttttgaa acatagactt cgacaaccga aatcgttgta tcactatcaa
    12121 atccccatag acggtcaaaa atctgcgtct taggcaaaat cacattttga ttttgaagga
    12181 aataaactag taaatcgaac tctttcccca gcaattcgac aggagtatct tcaactttaa
    12241 cggtattggt tgataaatta accacgatat tcccataagt caaggtgttt tcattaaact
    12301 tccctgaacg tttaagaagg gcctgaatcc gcattttaag ttcttctagg tagaaaggtt
    12361 tggtcagata atcatccgct cccagttcaa atccatgtcc cttgtcatcc aaactttcct
    12421 tggcagtcat aatcagaact ggtgtcgtaa ttcccttttc acgcaattct tttaagactt
    12481 ggaaaccatt tttttctggc aacatcaaat ccagcaaaat caagtcatag acaccactct
    12541 cagcttcgta gagaccttct tctccatcaa atacctgcat aacatccgca aaatcgtcta
    12601 aaaagtcaaa tactgaattt gacagaccta ggtcatcctc aaccaataag atttttatca
    12661 tgagaaactc ctccttatta aaactattat accaaatttg ccttaaaaaa aactcaactc
    12721 tctgcatttt acatgagata gctgagtttt ctttttattt taggcttatt tatgcatttc
    12781 cgtattgaag aacaactgct tcgactgcag ctttttcacg gctaatcaag tcaacacgtg
    12841 ctgcaatttc cttgattccc ataccgatgt tacggctaag agcaaggtca gaaagttgcg
    12901 gctcaaagaa ctccttgtat tccgccaagc gttgctgagt cttaaataca tgagcaggaa
    12961 ggataacaaa gctatcaaag ctcatatctc ctccaagggc tgccttaatc caagcccagt
    13021 tttcacgcgc ccaagaccaa gctgttttct gagttgcttg atgagctagg aattggtaat
    13081 accaagcaga caagtcctgt ggtttgacca caaatttgtc cttccaagaa gtaatcaagt
    13141 tttggatatt atccgcatct gtactgtatg caagagctgc tgccaactgg cgtttaaaga
    13201 cagcatctgt tgcgtgagta taagtatcaa gataaagtgc taacaagtct ttagtctcat
    13261 gatgtttcat ctcattaatc agaacttgtg aacgaatagc tgctgggagt cctgcaagat
    13321 tctccttgtg tgttgcgaag atttggctag cgacttgact agcttctgca tcatttgagc
    13381 gaatcatcat cgaaacagcc agctgacgaa ccaattcatc ctcatctgat tctccgtctt
    13441 tagcttcaaa accaagacgg tcatagttat gacgagccaa tttagcaacc agtcctttga
    13501 aggctgtttc agcatccgtt ccttcatcaa taaagcgctc aagggctgaa atcacttgag
    13561 aaacagctga aaccaccaga taagactctt ccttagcaag tttatcaaga actggaagca
    13621 agtctgcata agaaatgtgc cctgcctcag ccaacaaacg acgttcttga acaatttgca
    13681 gtttgcttgt gttatcaagt gtctctagct cagcaagaac agcttctaac aagtctcctt
    13741 gatagtcggt aatatagtgg gcagtatttt cagtgttgag acgaagagct ccttcatttt
    13801 cagcaagaag agctgcgtag ccagggattt cgatactttc agtttcgagt gtatcaggca
    13861 agcctttcca gttgctattg aggggcacca cccagagacg gttcttgtct tcgttctcac
    13921 cgatgaagaa ttgtttttgt gaaatcttca agacatcatt ttcaactttg acagtaagaa
    13981 ctgggtaacc aggctgttcc aaccaagaat ccatgaaggc tgcgacatca cgtcctgacg
    14041 cttgaccaag ggcatcccaa aggtcactac caatggtgtt gctgtattgg tgtttttcaa
    14101 agtaggcgtg caaaccttta gcaaaatcag catctcctag ccaacggcga agcatgtgca
    14161 tgagacggct tcctttggca tagacgatag cgccgtcaaa gagtgtattg atttcatctg
    14221 gatgtttaac ttcgacgtgg acagactgaa cgccatcagt agcgtcacgt tcaagagcaa
    14281 gaggtactcc acctgtttgg aaatcttcaa agatattcca gcttggttcg atggtatcca
    14341 cacagacgta ttccatcata ttagcgaaac tttcattgag ccaaaggtca tcccaccatt
    14401 tcatagtcac gaggttccca aaccattggt gagccaattc atgggccaca acaagggcaa
    14461 cttgttgacg gctagcaaat gtagagttct catcgacaac caagtaaact tcacggtagg
    14521 tcacaagacc ccagttttcc atagcaccag ctgagaagtc aggaagggcg atgtggagag
    14581 attgaggaat tgggtactta actccatagt aatcttcgta aaactcgata gagcgaacag
    14641 cgatatccag tgagaaatca agatttgaaa gtggatgtgc tttggttgag tagacaccta
    14701 ccagggtacc atttttagtt ttagcggtca ccccttgcaa atcaccagca acaaaggcca
    14761 acaagtaaga agacatgcga ggtgttgtct caaacttcca gatacctgtt tccttacggt
    14821 tttcaacatc gatttctggc atgtttgaca aggccaattc accttctgct tggtcaaagc
    14881 gaagagagag gtcaaaagtt gctttggctt caggctcatc cacacacggg aaagcttcac
    14941 gcgcaaaatg gctctcgaac tgagtagaca agacctcctt cttgactcca tcaactgtat
    15001 aataagaagg gtaaatccct gtcatgttgt ctgtaatttt accagaaaag gcaagaacca
    15061 attcaacttg accagcctca gccaattcga tatgaagggc ttcattgtca tggtcaactg
    15121 taaatggacg agcttgacct gcaacttcta cagaggtgat ttccaagtct ttttggtgga
    15181 gggagatgcg gtcactctgt gcttgaccag tgatggtcac tttcccagaa aaagtcttgg
    15241 tctcacgact caaatctaaa aataaatcat aatgttcagg aacaaattgc ttaataaaat
    15301 gttcaactgc ttgcatagtt ttctcctatt ctaagtttaa gagctgctgc tcttcttcaa
    15361 acaaacttat tatatcatat tttgcttgag aaaaaaggat tggacagcga tttccaaaac
    15421 tttcttcctt ctaatagtct acagtgggta gaccttgcga aattcttcta aaacaacctt
    15481 gctttcaggt gtaaaagtca gccctacttc acccaaacag tctgtgaaaa agtcctcatg
    15541 aacctggcgc caataggcaa gtgatttgtc tccctcacct tccttaaagg catgttgcgc
    15601 agaaacttga ttgaagagtt caacagaaac ctttgtaatt tcgacaatgc agacagcctg
    15661 attttgacta tctaaaatga catcgaaggt ccctacttgg ggaagtggtt cgtcttctag
    15721 tacatagagg tcataggctg atgctgttgc tgtcttttct cctttaaaca ccaaatccgc
    15781 taaaaggtct ggttcaactc caaaagccca agcatcgatt tcatctccga tcaaaggatt
    15841 gatttgcttg tatttattcc acatttcttg cggtgtcatg ggtactcctt tgtaattttt
    15901 tactttcttc ttttatgtgt ttaagatgat ctggatggtc aatctctaaa tcaaaaatct
    15961 ctggaataga actgtagtgg ataatgcact tgatacccaa ctgattcatt ttttgtatga
    16021 aagaagtatt cagatagcct gctacagcaa aattaatctt gttctttctt gctttatcct
    16081 gcatatctct tagcatatct aacattattg gactttccat atcatgccat tgactgtttc
    16141 tcatagtcgc aaaaacaaag gaagtcaaat cattcattcc aactacaatc tttgaaatgc
    16201 ccgtttccag tatactagat aagtcaaaat acgctgacgg taattcaatc atcgttccga
    16261 ctttcccagt aaagccatac tgacgcaata ctgtaatagc ttgttttaat tggtcggcat
    16321 cattgacaaa aggaaagata acagatagat tggggttggt ttgataaact tctgtaatga
    16381 catgtgcttc agcctgaaat tcatccaaac acgccagtaa acgcctagtt cctctatagc
    16441 caaacagagg ataaattttt tcaagaattt tttcgccact aagggcaagt tgatttttca
    16501 tagccattca cctcgtctta aaagatacaa tatcatatat aattatatca aaatttcctc
    16561 tagttcaaaa gcttcataag gttcagataa ctcatatcct aaaaattctg ctactttttt
    16621 ggaagcctca ttatgagcat cccaaagtgg aaacatatct ctatttaaac tctctagaat
    16681 cattgcagca ccaagctttt tagcaaatcc atttccttgt tcgtttggtc tagttgcaac
    16741 ttccacttca actgctttac ggtaaactaa ccctgaggaa atcccagcaa tcagttcatt
    16801 atttttaaga atcacaaagc caaatccacc ttttaaaaca aaatcctgat aggactcaaa
    16861 atccccctgt aaatcctgtg accattcttc cgtagaaaag cagttataaa tatgattatc
    16921 aataggcaca atattgtaac cttcctctaa atgagtaact agattattta aaaattcaac
    16981 ttgaaaattt gccttatctt taaaagaata gcgagtaaaa gaatttagcc ccacttttcg
    17041 atgcagaaaa tcttgccaat tagtattttc tgaaataata atcttataat ctaaaccata
    17101 ttttctaaca aaatcttccc aaaatctgga atccaactcc cctgctaggt atagaaaatt
    17161 cccaacatca taaaagcttg ttgtcctatc attgtttcgg tagacagttc caatttgaga
    17221 tttaagacca tagagaacca tatttttctt ccatgtttta aatagttcca ttatccctct
    17281 acttcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17341 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17401 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17461 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    17521 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    17581 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    17641 gactgcctcc aggtagatca taccgatgtt gataaggacc tctcgttttt tcaatgcaga
    17701 gtaactttcc attttcaaag caaacacagt agaccccaaa gtgatttttg atttccatcc
    17761 aactcctcct acttcaaaga ccagccacca tctattgtca gaatttgtcc ctgcatggca
    17821 gatgcctttc cactggccaa aaagagactg acttctgcca cttcctctgg ttcaatccag
    17881 cgcttgattg gtgtttcact agccacccag tcagctaagc cacctggctc aaaatccgca
    17941 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18001 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18061 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18121 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18181 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18241 tccaaaactc cagcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18301 tccaagtcca aggtcaaatc tctctgtaaa aagcgaaaat caccctctaa gagtggcttt
    18361 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18421 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18481 atccgttgcc aaaacatcac aaactgtcgg gctccacatg gaaaaacctt ctccttcgcc
    18541 agaaacgttg attaggaaat aaggtgtcat ttcaagtgca agcccatttt gctcgatggt
    18601 atcaaagagt tggacatagt tttccgcacc tccccaacca gttcgtacat attttctctt
    18661 agcctttaac ccaggcagga tctcttcaaa tgtcatgttt ttctccttta attctacatt
    18721 cttcatttaa ttatagcaaa aaaccgcttt atacggcttt ttaaatgtga gttattcaaa
    18781 cctgctacta cttacggcaa attattccct gcagcaagat aaatttcata ccattctttt
    18841 cttgttaagc taaagtttgc cgctcggcta acttctctca agtgcttagg atttgttgta
    18901 cctacgactg cctgcatttt tgctggataa cgcaatatcc aagaaatggc aatagttgaa
    18961 gaggttactc catatttaat agctaaacga tcaagtactt gatttaaagc ttgaaatttc
    19021 tcatttccaa caaaattccc tttaaaatac ccgaattgta agacagacca tgcttgaatg
    19081 accacatcgt gtaattggca atattcaaaa atgctgccat ctcgcatagc tgcttgacta
    19141 tcttccatat taacatgaaa agctgattca aatcctggag taaaagccgc actcaattgt
    19201 agctgattaa cagctaacgg ctgcttgaca tcttttttaa gcaactccat catcatagga
    19261 ttttgattag aaactccaaa atctcgaact ttaccttgtt tataaaggag attaaaggct
    19321 tctgctactt ggtcagattc catcaaagca tctggtcgat gaaggagcaa gctatctaga
    19381 tgatcaatct tcaatctttg caaaataccg tctactgatt ttataatata gtccttagaa
    19441 aaatcaaaat aggtaaattc ttcaatgcga atgccacatt tggactgaat ccacatcttt
    19501 tctcttaaat ctggacgatt ttttaggaca agacctaaca gttcttcaca acgaccacga
    19561 ccataaatat cagccaagtc gaaggcattg attccaacag aaagtgctgt ttctacaagc
    19621 tcttcaactt cttttacaga tttatctttt attctcatca ttccgagaac aatttctgat
    19681 aattctttgt catcttgacc aagagttatg tatctcatca aatttttctc ctttaatttc
    19741 taacattctt cccttcatta taacaaaaaa ccgctttgca acgacttttt gactatactt
    19801 cactccattt tatcttctta aacccacgga acaagacaaa gattccaata aagaggacag
    19861 ctaaaggaat aacttttgta aggaaaacat ttgaaattcc catccactca taataacgga
    19921 gcagagaacc caccacaaga tgggcaataa tcatactgac aaatggacga aagaccgctt
    19981 ctttccaatt ccaaataccg ataactagcg aaatcgtaaa gatagacaaa ctatcccagg
    20041 gagccggaat ataaaaggct ccttcttgta tgaagcttgc cattcctaca tatcctaaaa
    20101 caactagaag aactatagtc ccaacaacaa tgtaagtgcc aattttcatt ttaggagaat
    20161 cttggactaa acttcttcgt aaaattgtgg ccacaagtcc aaatccaatc agaaaaataa
    20221 gaagttgccc taaaaatgtg agcaaattga ctgttaagag aggaccttta gaaaaatcac
    20281 ttagtagttg ataataacgt aataccgcca ggacaagaat tggcgtcaaa agggactctt
    20341 tgatagaact gcgaggtgct cccttgagaa tctctttcat tattttttta ggattcttac
    20401 ctagataatc ctctgcactc atgccatctc gttctgcttc tgagaaatct agcatcatca
    20461 aatagatctg ctctctgaga tagtcttcat catagagaaa tccagcaaga ttaaaacttt
    20521 cccacaactc ctcaaaatac ttttgattct cctcagaaaa ctcatgtagc aaagcgcttg
    20581 tttcttcgta atacttcatt ttcttcatgg tttaaccccc attcttaatc ccttctactt
    20641 tttgactcaa atcgtcccat tgttgccaaa agactgagac acgctcttct ccttctttca
    20701 ttaatgaaaa atacttccga tctggaccat ctggcgacgg gcgcatgtcg cctcttatcc
    20761 attgattttt ttctaacttt tgcaacaaag gataaatagt tcctggaacg atagtatcaa
    20821 atccagcctc tcgcaaagtc tgaaccaact cataaccata ccgctctttt tgaccaatca
    20881 tatccaagac acaaccttca agaacacctt ttaatagctg agtttctttc atcacttctc
    20941 ccttctaatc tattttgtaa tacctactag taacttcacc tatagtatat tacttctaca
    21001 ctagtttgta aagcataata gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt
    21061 cgccctaccg tatgtatggt t
//
LOCUS       DAVHSL010000037        21058 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000037 DAVHSL010000000
VERSION     DAVHSL010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.038"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(1..516)
                     /locus_tag="VVR39_001434"
                     /pseudo
     CDS             complement(1..516)
                     /locus_tag="VVR39_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            1004..1123
                     /locus_tag="VVR39_001435"
     CDS             1004..1123
                     /locus_tag="VVR39_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU6030904.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(1213..2559)
                     /gene="glnA"
                     /locus_tag="VVR39_001436"
     CDS             complement(1213..2559)
                     /gene="glnA"
                     /locus_tag="VVR39_001436"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU6030905.1"
                     /translation="MPITAADIRREVNEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2596..2952)
                     /gene="glnR"
                     /locus_tag="VVR39_001437"
     CDS             complement(2596..2952)
                     /gene="glnR"
                     /locus_tag="VVR39_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU6030906.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3029..3556)
                     /locus_tag="VVR39_001438"
     CDS             complement(3029..3556)
                     /locus_tag="VVR39_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6030907.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3692..4888)
                     /locus_tag="VVR39_001439"
     CDS             complement(3692..4888)
                     /locus_tag="VVR39_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU6030908.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQTG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4978..9918)
                     /locus_tag="VVR39_001440"
     CDS             complement(4978..9918)
                     /locus_tag="VVR39_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU6030909.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQIPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAIVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            10211..11842
                     /locus_tag="VVR39_001441"
     CDS             10211..11842
                     /locus_tag="VVR39_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU6030910.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSSAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTAYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(12401..14008)
                     /locus_tag="VVR39_001442"
     CDS             complement(12401..14008)
                     /locus_tag="VVR39_001442"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU6030911.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14398..14985)
                     /locus_tag="VVR39_001443"
     CDS             complement(14398..14985)
                     /locus_tag="VVR39_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU6030912.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15113..15562)
                     /locus_tag="VVR39_001444"
     CDS             complement(15113..15562)
                     /locus_tag="VVR39_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6030913.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDWHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15567..15955)
                     /locus_tag="VVR39_001445"
                     /pseudo
     CDS             complement(15567..15955)
                     /locus_tag="VVR39_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
     gene            complement(15982..16608)
                     /locus_tag="VVR39_001446"
     CDS             complement(15982..16608)
                     /locus_tag="VVR39_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6030914.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16622..17185)
                     /locus_tag="VVR39_001447"
     CDS             complement(16622..17185)
                     /locus_tag="VVR39_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6030915.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17350..17584)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17638..18141)
                     /locus_tag="VVR39_001448"
     CDS             complement(17638..18141)
                     /locus_tag="VVR39_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU6030916.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18334..19164)
                     /locus_tag="VVR39_001449"
     CDS             complement(18334..19164)
                     /locus_tag="VVR39_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6030917.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(19149..20831)
                     /locus_tag="VVR39_001450"
     CDS             complement(19149..20831)
                     /locus_tag="VVR39_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030918.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         6116 a         4643 c         3840 g         6459 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggggag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtgctt ccatcagcaa acttcccata atgtttctta tgtgcttcaa gtatataaaa
      541 aggcgtaaaa atacgcctat agataatggg gttgaaatag gtttattgtt gatgagattg
      601 tagataattc aattttttac ttccaatcga atattcaaaa cctccacctt ttctgcctgt
      661 aattgttcat cataaaattc aatatcttca ggattttccc cttggcaacc tcggcagaaa
      721 tattcttccg ctcgatcagg attcaaaaat cgacaagcac aaacaaaaca gtcgccatca
      781 tcatttattg agataatata gtagattgaa ataagatgta aacaaatcga ttaggaaagt
      841 taaattagtt tctagaaatt tttagcagat gtagtgtact attctagtct caatttacta
      901 tggcttcaaa tatatctttc gaaaaaatat ttacagatgt gtaattttga agcttgcaaa
      961 agttagtaaa cttgtagatt tcgatttgaa gtaacttgtt ttcttgcccg atattgtttt
     1021 tgaaattgaa tttttccata gtgactcctt gattttcttc tacacgtctg atgataaatc
     1081 taattcgcaa aagagtcaag aggatttttc gaaaaataaa tagcgaccga aatcgctatt
     1141 ttaagggtta taggtatttg atggcttaga ctgctgtgtg actgtttacc cacaggcaat
     1201 ctttcttcta tattagtaaa ggtctaaata attatcaatt tcccattgtg aaacgaaggt
     1261 tgcataactt gcccattcga ttcgtttggc ttcaaggaag ctagtgtaga tgtgatctcc
     1321 gagagcagct ttaaccactt catcttctgt caaagctttc aaagcgttgt gaagagttga
     1381 tggaaggtct gtaataccag cttccttgcg ctcttctgct gtcatgatgt agatattttc
     1441 ttcgatagga gctggtgctt cgattttatt ttcaatacca tacaaaccaa cttctaaaag
     1501 aacagccata gcaatgtaag ggttcgccat tggatccact gaacgcaact caagacgagt
     1561 tcccatacca cgtgaagcag gtacgcgcac aagtggcgaa cggttacgac cagcccaagc
     1621 aatgtaaaca ggcgcttcat aacctggaac caaacgtttg tatgagttaa ctgttggatt
     1681 catgatggca gtatagttgt aagcatgctt gatcaaaccg cctaggaaat ggtaagctgt
     1741 ttctgacagc tgcattcctt ttggatcatt tggatcaaag aaggcgttat ttccttctgc
     1801 atcaaacaag gacatattac agtgcatacc tgagccagca ataccaaatt ttggcttcgc
     1861 cataaatgtt gcgtaaagtc cgtgtttgcg agcaatggtt ttaacaacaa gtttaaagat
     1921 ttgaatctta tcacaagcac ggagaacttc atcgtactta aagtcaatct catgctgtcc
     1981 aaccgcaacc tcgtggtgac tcgcttctac ttcaaatccc attttggtca agacattcac
     2041 aatctcacga cgtgtgttgt ccgcaaggtc agtaggtgcc aaatcaaagt agccaccctt
     2101 gtcattcact tcaagtgttg ggtccccatt ttcatccaac ttaaatagga agaattctgg
     2161 ctctggacca aggttgaagg atttgaatcc aacttcttcc atgtgacgaa gagctcgttt
     2221 caaattacca cgagggtcac ccgcaaatgg ttcaccttct gttgtataaa catcacagat
     2281 cagacctgca acacttccat tttcatctcc ccaagggaag actgtccatg tatccaagtc
     2341 cgggtacaag tacatatccg actcattgat acgtacaaaa ccttcaatag aagatccatc
     2401 aaacataacc ttgttcgaca agaccttatc taactgttca tctgtagcag gaatttcgac
     2461 gtttttcatg gttcccaaaa tatctgagaa cataagacga ataaaggtaa catttttttc
     2521 attgacttca cgacgaatat ctgcagctgt gattggcata agttttctcc ttaatctatg
     2581 actacttgcg gttgcctaac cgcgaccaaa aggtgactgt actgaagcaa aacgcccctg
     2641 ttggaggagt tcattgtgaa gtgcacgacg tacttcagtc tgactaaccg ctttcttgga
     2701 tttcgcttca cgttcagcat attttttctt aatggcagcg atattataac cttcagagat
     2761 ataatctttg atttcaagca gacgatccat gtcattcaag gaatacatgc gacgatttcc
     2821 ttcgtttcga tcgggcttga tcaactcttg atcttcataa taacgaatct gacgcgccga
     2881 taaatcggtc aacttcataa cactgccgat aggaaaaaca gccatatttc ggcgaaattc
     2941 tttttccttc atttacaatt tccttctttc tgtctattat agtctaaaaa aagacaaacg
     3001 tcaattgata atgttataaa atgtaacatt atttttcttt tttctctaaa aagagacgaa
     3061 tacgatcaat atcgtaattt acgataattg cgacaaaaac tcccataaac gtttctaata
     3121 cacgtacaaa cacgtacaaa attgtctcac cacttggaat tgatagggta atgattaaca
     3181 tagctgctac accaccaata acccctgctt tgttattcat ggctacattt gtcataatgg
     3241 ttaacatggt gcagattgga acaactacta aggtcaccca aaaggcttcg tggaaaaaag
     3301 tatttaataa gaagaagacc aaggcataga gtccaccgat actatttcct agaatacgcg
     3361 aagtcccaaa atgaacactc tcatcaaaac tctccctcag gctaaaaacg gctgtcaaag
     3421 caccaatttg aagacctttc cagccaaaaa agccaaaaat caagagaact agaaaaacag
     3481 caatacctgt tttaaaggtt cgcataccaa gtttgaactg ggatttatcg aatttatatt
     3541 ttttaaaata actcataatc tcaactttct atttccattt tatcataaat cggtgatttt
     3601 tatgagtaat agttgagagg aagcgttttt attttaagca aaagaaaaga ggaactttca
     3661 tccctctctt ctttgatttg tttataaaat cttatttttc tgtcaaggct gcaagtcctg
     3721 gaagaacctt accttcaaga agttccattg atgctccacc acccgtacta atccatgaga
     3781 acttatctgc acgtccaagg ttgatcgctg cagcagctga gtcaccacca ccgatgattg
     3841 atttaacacc tggttgtttc acgatagcgt ccatcacacc gattgtacca gtttggaaat
     3901 ctgggttttc aaatacaccc ataggtccgt tccatacaac tgttttggca ccagtcaaag
     3961 cttcgtcaaa tttagcgata gattttggac cgatatcaag accaaggaag ccttcagaaa
     4021 ctgcttcacc ttcagtgtca cgcacttcag tgtaaccagc aaatgcgtta gcttcttttg
     4081 agtcaactgg caagatcaat ttaccgtttg ctttttcaag aagagctttc gcaacatcca
     4141 atttgtcttc ttctacaagt gagttaccga tttcgatacc ttgtgctttg tagaatgtgt
     4201 aagtcatacc accaccgata aggactttgt cagctttttc aagcaagttt tcgataacac
     4261 caatcttgtc tgaaactttt gaaccaccaa ggatagccac gaatggacgc tctggagttt
     4321 caactgcttc ttggatgtag gcaatttcgt tttcaagaag gaaaccagca actgcttttt
     4381 caacgtttgc tgagatacca acgttagatg cgtgtgcacg gtgagctgta ccgaatgcat
     4441 cgtttacgaa gataccatct ccaagtgatg cccagtattt accaagttca ggatcgtttt
     4501 tagattcttt cttgccgtca acatcttcgt aacgagtgtt ttcaaccaag agaacttgtc
     4561 catcttcaag agcgttgatt gccgcttcca attcagcacc acgagtgaca cctgggaaaa
     4621 caacatcttg accaagtttt gctgccaagt cagctgctac aggagcaagt gatttgccag
     4681 ctttatcagc ttcttctttc acacgtccaa ggtgagagaa aagaattgca cgtccacctt
     4741 gttcgatgat gtacttaata gttggaagag ctgctgtgat acggttatcg ttagtgatta
     4801 cgccatcttt caatggtacg ttgaagtcaa cacgaacgag gactttttta cctttcaagt
     4861 caacgtcttt aacagtaagt tttgccatgt tacaaaaact cctttattta ttttattcga
     4921 aactattata tcacactttg gaaatataag gaaagatttc acaagatttt tcgatattta
     4981 atctttatct tctcttttcc gtctcaaggt caaggctaaa ctagcaagac caaggctggc
     5041 taagcctgct attagggctt cattagcatc agctgttcct gtatttggca attgtttgct
     5101 tgcttcttct gatttaactg ctgtattttg agctggtttt tcctgtgtag ctactattgc
     5161 tggtactgtt tttacttttg ttccaatttc aacaatttct ggaatcgctt cttggatgac
     5221 ttctgttgaa cgaagacgac gctgaccgtt ttcatcaact tcaaagacat gtcttaacag
     5281 tccatctcgt ccctgtatga tgactcgttg ttccccaact agcatctcag cattttcatg
     5341 ctcttgacga tgaaaggcaa ccttttcctc ttgaacttcc aatttaggag ccttttgttg
     5401 atcagaagcc ggttgataag taggttttgg aaggactttg ttttgtggtg ctggtttagc
     5461 aggttgtggt ttttcagcag attcataaac aaaggcataa tgagtaaagt gtggtgctgt
     5521 aaagataaca tgactatccg tttgttcaaa agccaattct actgcctctt tgccttcagg
     5581 taagaaaaat actttcttaa ctttcttatc tttttcaatt gggattttca caatagaagc
     5641 gtaagagaga tcaacatctt gacctttttc atccaaacct tctatttcaa agacatgagc
     5701 atcttctcca gcaaagtatt tcttctcttc agcacttgct tgaacacgct ctactttcaa
     5761 acccttgatg acagtcttct ctttatttga gaagtgtact tcaacacctg ttttactatc
     5821 agaaaagact gctggcttgt cttctttcaa taaagcaacc agatctttta gactctgttt
     5881 cgctgttgca agctcttctg gactcaaatc tactttttca accaaggcct tgtttttctc
     5941 aagaagcgga gctagggcag aacctgaagg atggtttggt ttggcagcca agagttcttg
     6001 aacctcacct gttaaacgat caagctctgt cttttcttcc ttaaatttct cttgaccatt
     6061 cagagcttta tgagcttctg tcaatttatt aagtcggtca ttgacttgat cttgggtgct
     6121 aatttcatgg tctttcaaca cttgttcggc cgcttcaatt gctttcaaga aggcttcttt
     6181 tacttctgat gaagcaaagt tatagaccac cttgttctta gcagcttcaa cttctgctaa
     6241 tttttgtttg aggtactcat cgttcaatgc tgcttttgga gataccaaaa catcaaagct
     6301 aacttcatgg ccttggtaat gaagcgtcaa ggtttgacga ccagtctttt gagcatcgta
     6361 accagaaatt tcaactccct catcagtaaa ggaatgttct tccatggtgt cattgctata
     6421 agccactgca aagcgtcctt cagacaagtc taagctatca ccaactaggt aatctttttt
     6481 cggttcctga cttacttcaa ttcccaaaat agttttcgga cttgcttcgt cttggccagt
     6541 gacagtcact gacaaattag catttactgg ttgtcccaaa tattggagag taagattctg
     6601 ttctccctta tgatgcgtat caaaacctga tactgataca cctgcgtgag ttaggcgaat
     6661 gagttcgtcc tcagttcctc cttcatactg aactcgaaga acaccacctc taaggtccaa
     6721 atcctcccct tcggcgtagc ttgttttctt aggtcctgtt tctaggctga ctgacttgat
     6781 tcttctgtca tcttttggaa cggaaactgc taggacatta ctaatttcct tgcctggcaa
     6841 ctgggtacga taataaagaa gaccagattg atttgtcaaa tccaatggtg cacttgctag
     6901 gtctcctcca acttcgctct tcaaggttgc gagcggaatt tgagaatttg gattatcata
     6961 aacggtaata gttgctccag ccggtacatc tgcaaagcca acttgtacct tgttattgcc
     7021 tagagaacgg gctgcagcct tggccatcgg aatattgaca ctctcagtat caagcttttc
     7081 atacattttc cagttataga tacgaatagc cttccatgga gttccattgt cagaagtgac
     7141 aacattcaag cgccagtctt gagcagtgat tggtttatca agagtgatat ctgtcacgtg
     7201 tgctttgtta ccacggactt ccttagctag cttccactca ccatctgcat ctttataata
     7261 aaggtcaaag tctttggtgt tcatcaaacc atcgttaaca gactcaccac cagctcctgc
     7321 atgatccatg acccatctaa caacggtacg tggcttggtc aaacgaatat ccacactacc
     7381 actcaactga gctgaagacc atttatctga caagctagta atggtaccgt tcaacatacc
     7441 ttcaatacct tctccacctt cagtcttagg gaaagtacta tcaataactg ttgcacctgg
     7501 aacgatattt tcagctagtg gttttggtag gctggtatct tttacagtca taccccaatc
     7561 aaaggttgtg gttgcagctt ctgaacgaac tccattttta ccgactgcta caaccttcag
     7621 ttcttgagtt gtaccctgag cacttgctga gcggctaact tttggtagat aaatagttgt
     7681 agaagatgag ccagttagta atttccagct gtctccatct ttttcataaa cttcatagaa
     7741 atctgcatcc ttgttgcctt taaattgcac aactgcttcc gcttcttggg catttttaag
     7801 cgattgtttc actacagaaa agcttgtcgg cgattgtggc tcttggtgat tgtccgagat
     7861 agttaattgt ccgaggttga actgataatc ttttacagca ccttcatgct cgaaaaatag
     7921 tttgactgca tagatggttt tacctgctag tgagctgaga tcaaattctt catttgtcca
     7981 gttgtcagaa agggttagct ctttccatgc atctgcatca tcgaatttgt agtctggagt
     8041 tgtagagaat gccatataaa ctttagaacc ttttcctccc ttgtgggcaa cacgaagttt
     8101 ggtcttctca gttacttcta acttagtaga ataaagtctc acatcctgat ctgtcttacc
     8161 ggctacatca ccagagaatt taagggaatt tccgccatta taggcatctg taaaatcata
     8221 ttctgcacga agtttttccc ctgttgaagt ctgccaccag cgccatgttg gaagaacacc
     8281 tgatactgaa cgataattcc actcagaatc cttagaaacc ttaccatcta cgaaccattt
     8341 tttaccatga cctgtattaa aagaagtagt aaaagtatta cctaccgctg gcgtacggtc
     8401 cgcaactagg ttagcaatac cataccaatc tttgtcacct ggtttttggc cagtggggtc
     8461 tccttgataa cctgtaaaga agatatcttc atttttatga taatcttcac cagtttttcc
     8521 taaacttgta atggtatctg gggcaaataa accaagagaa aggcgcaatt tcccattttc
     8581 gtctaaaatg tcattccact taacctttgt cttgtaggaa ccaccctgtt gcaattccaa
     8641 acctgcaaat acatcataag gattacgacc aatccagttg gcagttgcaa tagtgtaatc
     8701 atttttagcc ttatcccagt taaagttagc aaagaagtta tctgccggaa ccttatctcc
     8761 ttctggttgc atgaattggt agttgtattc tcccaaacca tcttgatggt aacgtccata
     8821 gttataggtc atggcatcat accaagaata cttgattgga tggtttacct tagcagcata
     8881 ttccttgcta tagagcataa actggcgcat cttttctcca agaggtttaa ccaaatctcc
     8941 agttgtttct tggttgatga aatagccatc atagccataa tacttggcca tgtctaccaa
     9001 tttacgggca attgggaagc taccatctgc gtcttgcttc aaagcttcag caaatctttc
     9061 ttgatctgca atactattag accagttgaa gaagagtgta ccgtatacag gaaccccgtt
     9121 acggtgacct gcatcaataa cgtcaggagt tggtacgaga ccttcccaga agaccattga
     9181 atctagatat tgccaatagt caaaagcata ggccttgaac tcttctccac caacagaagc
     9241 atggtctttt gctttagaat tggtgtttga taaggcttga acttttgctt ccttgctagc
     9301 tttttcattg actagatgac ctgtccgacg tgaagcgagg acaacagatc cgcggttaat
     9361 agcatcatct tcacgagcac ctggttccca ttttaacaat tcttcccaag aattaaattt
     9421 gatttccttt ggttttaatg ttttttctgt atttttaggg acatctggct ggacttcttt
     9481 ttcagtctta ttagcttctg ctgctggttt agactcatcc ccttggttag ttgcttcggg
     9541 ctttgcttct gtttccttgt cagacttagg ttttgcttct gcagatggtg tttctgcaac
     9601 cacctcacct gctttttcct ctggtttagc tgcgctagct gcttctgcag tttcagatgc
     9661 tgtcgctact ccttctgcct tttctagctt gttttctcta gcatgttccc cttcattctg
     9721 cttatcagct tcattggtcg aatgctcact ctctcctgaa acaagctctg tattagctcc
     9781 gctattttca ggaactgcag tttcttcagc caaggctgga ccagcaaata aaacagcacc
     9841 aatcatcagc gagcaggctc ctactgataa cttacgaata ctgtaacgac aacgtctttc
     9901 aaaaaatgga ttcttcattt tctcctccta aaagattgat tttgttgttt tcaagaaagc
     9961 gctttatatt ctgtagtttt ttatcaaact ctagaaccat gataatcaca tttttatcct
    10021 aaaacatttt tagacaaaaa acaataactg tttgcacaaa tctaaaataa ggttaaaaac
    10081 tcttaaaaat aatacactta tcaattataa ttttctttta caaacttgac attaacactt
    10141 gttagattta cttttatcct ttaaaataga ataggagata ttccgcgatt atttttcgga
    10201 ggaaaaagaa atgtccatta attggcagga aattttattt cactttttag gtggtctggg
    10261 gctattctta tatagcatca agaccatggg agacggttta caacaagctg ctggagatcg
    10321 ccttcgtttt tacattgaca aatatactag taatcctttc tttggagttc tggttggtat
    10381 tgggatgact gctctaattc agtctagttc tggtgtaaca gttatcacag tcggcctggt
    10441 cagtgccggt ctcttaacct tacgtcaggc tatcgggatt gtcatgggtg ctaatattgg
    10501 gacaactgtc acatcctttc tcatcggttt taaattaggt aactatgccc tacctatgct
    10561 ctttatcggt gccgtctgtc tcttttttac gaaaaatcgg acagtcaata atatcggacg
    10621 catcctcttt ggtgtcggtg gtatcttttt tgccctcaat ctcatgagca gcgcaatggc
    10681 tccactcaag gatttacagg tctttaagga ctatatgatt gagctaagta agaatcctgt
    10741 tttgggtgtc tttgtcggta ctggcttgac cttgctaatt caagcttctt cggctaccat
    10801 tgggatttta caaaacctct acgccggcaa tctaattgat ctacagggag ctttgccagt
    10861 tctatttggt gacaatatcg ggacaaccat tacagccatc attgcctctt taggggctaa
    10921 tattgcagct aaacgggtag caggagctca tgttgccttc aacgttatcg gaacagttgt
    10981 ctgcgttatt tttctagttc cttttactgt cctgattcat tggtttgaag ctacgctaaa
    11041 tctagcaccg gaaatgacca tcgcctttgc tcacggaacc tttaatatta ccaacaccat
    11101 tgtccaattt ccatttatcg gagctctggc ttactttgta accaagatta ttcctggaga
    11161 ggacgaggtt gtcaaatacg aacccttata tcttgatgaa catttcatca aacaagcccc
    11221 atctatcgct ctaggaaatg ctaaaaaaga gctcttgcac ttaggaaact acgctgctaa
    11281 agcctttgac ctttcctata agtacatcat tgacttggat gaaaaagttg ctgaaaaagg
    11341 gcataaaacc gaagaagcaa ttaacaccat cgatgagcaa ttaacacgtt atctcattgc
    11401 cctttcaagc gaagctctca gccaaaaaga aagtgaagtg ctcaccaata tccttgattc
    11461 ctcccgtgat ttggaacgga ttggagacca cacggaggct ctactcaatc tgactgccta
    11521 tcttcaacgg aaaaatgttg aattttccga tgccgccttg aaagaattag aggaagttta
    11581 ccgccaaact agtgacttta tcaaagatgc tctggatagt gtggaaaaca atgatattga
    11641 aaaagcacgc agtcttgtag aacgtcatga agcaatcaat aagatagaac gtgttctcag
    11701 aaaaacccac atcaaacgcc tcaacaaagg cgaatgttca acacaagctg gggtcaactt
    11761 tatcgacatc atctcacact acactcgtgt atcagaccac gctatgaacc ttgctgaaaa
    11821 ggtttttgca gaacaaatct aagaaccaag aagctatcca tcataattgg atggcttttt
    11881 actttttcct aagcaagact aggctgaatg aaactgaaag agtattctgc agatatatag
    11941 tatattgaaa ctagaatagt acacctctat ttctaaaaca ttgttagaaa tcgatttgac
    12001 tgtcctgatc gatttgtcct gttcttattt cattttacta tagtggatta aattaaaaaa
    12061 gtataatgta ttgaatctat aacagtacat cttgactgct aaaatatttc tataaattaa
    12121 tttgactttt ctgatagaga tgttcacatc ttatttcaat tcactataca atccagttcc
    12181 taaaactttg ctagaaattg atttggcttt ccgaattaat ttgttcagat tttatttcat
    12241 ttcaatatac tgataaatcc attcactagc acagggcaag agggagtcgc tattaatttc
    12301 aacggtagca ggtacataca gaggactcct acctcagata tactgcaata tcattgtatg
    12361 caaaaaacct ctgagatttt tctcaaaggt tctgattttg ctaattgctg ttctcaaccg
    12421 ctgcagtaac aaaggcagtg tagagttctt ctggtcggtt tggacggctt gacagttcag
    12481 ggtgatactg acaagctaca aagaatttat tttcaggaat ttccacgatt tctaccaaac
    12541 gattgtctgg agaaactcct gaaaagacaa aacctgctgc ctcaaactgc tcacggaagg
    12601 cattattaaa ctcataacgg tgacggtgac ggcgttgcac cacttcttga ttgtgataag
    12661 cagcagcagc cttagagcca cgtttcaact tagacggata aagtcccaaa cgaagggttc
    12721 cacccatatc ctcaatatca atctgatcac gcatgatatc aatgataggg tattttgttt
    12781 ctggtgcaag ctctgcagaa ttggcacctt caagacctaa aacgtgacga gcaaactcga
    12841 tacatgtcaa ctgcattccc aagcagactc ccaacattgg aacatcattt tcacgcgcat
    12901 agcggatggc ttggattttc ccttctgtac cacgttgacc aaaaccacct ggtacgatga
    12961 tcccgtccgc atcagacaag agttctgcta cattctctgc tgtcacatca ttggcattga
    13021 cccaattgat tttaacttct acatcattga catagccaga gtgtttcaag gcttcgacca
    13081 ctgagatata ggcatcttgc aactccacat acttaccaac aagggaaatc ttaacttgtt
    13141 tcttgaggtt catgaccttg tccaccatgg ctgaccattc tgtcatatcc gctgctggtg
    13201 cgtctaattt caaatgatca caaacaattt ggtccatccc ttgtgcctgc aagttcagtg
    13261 gaatttggta aaggtgttca acatccaacg attcgataac ggcttctggt gccacatcac
    13321 agaactgggc cagtttattt ttaattcctt gaccagctgg ctcttctgta cgaataacca
    13381 acatatttgg ttggattccc aagccacgca attctttgac agagtgttgg gttggtttgg
    13441 ttttcatttc accagcagcc ttgaggtaag gaagcaaggt tgtatggata tacatgacat
    13501 tatccgcacc cacatctgcc ttcatctgac gaagagcctc taggaatggc aaggactcga
    13561 tatctcctac tgttccacca acctctgtga taatgacatc agagtcggtc gttagagcgg
    13621 cacgcttgat tttttctttc aaagcatctg tgatatgagg aatgacttga acagttgccc
    13681 caaggtattc tccacggcgt tctttacgaa gaacttcact gtaaattttc ccagttgtca
    13741 cgttggaata tttgttgaga ttgatatcga tgaaacgttc atagtgaccc aagtccaaat
    13801 ctgtctcagc tccgtcatct gtcacaaaaa cttccccgtg ctggtaagga ctcatggttc
    13861 ccggatcaat attgatataa gggtcaaact tttgaatggt tactttgaga ccacgatttt
    13921 tcaagagacg gcctagactc gctgccacaa tccctttccc aatagacgat accacaccac
    13981 cagttacaaa aatatatttc gtagacatag attcctcttt ctaaaatgct caaggtcttg
    14041 ttaactacga ggggatatag aaaacaagac cctactaata agaataatct gggacgactg
    14101 caccagattc acaactaata ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg
    14161 ccgtagatat gtgttcctga ctttgtcagt cttatctaca acctcaaaac agtgttttga
    14221 gcagcctacg gctagtttcc tagcttgctc tttgattttc attgagtata aaatacaaga
    14281 agataacttc ttgaaaaaac aaaaatagct ccctaagaac tagggagccc cgacctctaa
    14341 aagaggtgcc caaacaatat gatacctaaa aataggataa ttgtcaatag ctaactctta
    14401 ttcctcgctg gtttcagcgt cgtcatctga aaactcgtcg tcgtcttcgt tgagatccac
    14461 atcttctccc aagtcatctg gagcgatttc gttgatttct gcatcataag cttccacttc
    14521 atttttttca tcatctggat tttcatcatc gtatgaaaga gctggatctg cttcgtatgc
    14581 atcttcgtct tctggatcat ctgcattgta gtcaatggca tctgaatcac catccataaa
    14641 ggcattgaca cgttttttct tagcttttgg tgctacttca tcgtcgtcat tttcttcaag
    14701 agcgatgatt tcttcgtcga tttcgtccac accataccat gaacgaagac cccatttgtt
    14761 gtccccaagt gagatgaagc taccgtcaaa gttcaactct gtgtagaaca aaggcaaagc
    14821 ttcgcggata tcgctgtttg atgttccaag gtagttttga atttcgttta caagatcgct
    14881 aaaatgcatc tcatgatcgc gaccacgaag ttctaagata gcacgcgcta cctcaatcat
    14941 agatagttca cttttttctt gcccagcaaa tacttctaat tccaaagcgt ttctcctcat
    15001 ttatactact atcgtcagag cgaacagact ctgacctcat tttatcattt actctttatt
    15061 ttacgataat tttgcggaat agtcaaaggt taagggggag aaagtggcag gattagacta
    15121 attccaatat aaaactcctt cctttttctg ttgctccatt ttccacaaat ccaagcgact
    15181 tgaaacacct cctagaagca tgattgtagg tgtagatttc cttgactctc aattctttcc
    15241 atccttttac tcgagccaat tcaatcaaag cacttagaat cttttttcca agtcctcgat
    15301 gttggtaagc ggaattccca atcacaatgg ggagattatc ctgagatagt gtaatatccc
    15361 caattggaaa ccattctccc ttctccttga cttcaatcca aaaaagctca ccatgccaat
    15421 ccaaatagga atacatggct tccaaggtcg cttgactgta aggaagcttc accccatcta
    15481 cgaggtaaac caagttcaca tcctgatacc aagcaaaagc ttcctcacaa tgattgacct
    15541 tataataagg aacaaaacac aatgcactac cttttcaaca aaagagttgc tgcttgatta
    15601 aaaccatcac accagttata ccatttgctt catacccatc ttgagctagg atacgatctt
    15661 ttaaatcaaa aacagagtaa atctttcttt cctcgcaagc ttgcgcatag agatgatata
    15721 gttcatcacc accatctcta tcccactcag cagaaatcgt atcccgacct gccaataaaa
    15781 cctgataagc cctgtgatgc ccatctgtaa tcagcaaaca atctccaaag gcaagaatac
    15841 tgattcgatc gacttggatt gtttctgccg actggtaaag catctgaata tcttgcaact
    15901 tcttttctga taaatatagt tgagtcggat gaagatctgc tatattgact ttcatttctt
    15961 tctctcaagg gaattcgata ctcacttctg tttgccttta aatcgccatt ggaagcggag
    16021 cttgtcataa aagggaaact cgataaacag gactcccaag cccacacaga gactggcaag
    16081 gacgtctgat gggtaatgaa ctcccagata gactcttgat accagcacac tgactaggta
    16141 gaggccaagg acgatttgta cgatttttct ccagacctga tctttaatcc gctgactaag
    16201 aataacaatc aaagtcccta ccatcagcgt tacagctaga gaatgcccac ttgggaagga
    16261 aaatcccttc tcctccacca gatgtaaaat agctggtcgt gggcgctggt agatattttt
    16321 aaaggtcacg attaaaagac ctgccaaagc cagatttccc agcatgaaga aactttctat
    16381 cttccatcgc ttacgataaa agacaaaagc tgtaatgaca acccaagtga taatcactgg
    16441 gatatcaatc agacgtgtga gggctcgaaa aagaatagtc aaataatctg gtaagtctcc
    16501 tcgaatggca gtctgaatcg attggtcaaa attgaccaac atttcagggt aaaatttgac
    16561 catatagcca agaataacga aaagtaaaag ggcaaaactg cccttcatta aaaatgtttg
    16621 tttatctttc atagtgtttt aaggttggtt tcaaaaggac gtacaacaac cagaatgaaa
    16681 cggaaaagat tacaccctca atcaagttaa aaggtaatac catggtcatt aggtagttgg
    16741 aaagtcccaa aatttttcca atatcaaagt tagcaaactt agcgtacaaa ggaacagcat
    16801 aaacatagtt gagaaccaac atggccaagg ttaaaccaat agttccagct agagagccta
    16861 gtaggaaacg aagggttgtc cgttcctttt tccaaatcaa agcaaatacg atgacaaaaa
    16921 ctcccaaagc tacgatattc atcggcaaac caatgtaagt attcactcct tggctgttaa
    16981 gaagcaattt caatagtgag cgaagcaaga gcactcctag agcagcaggc aaatccatga
    17041 ccaccagacc cacaaggact ggcaagatac taaattcgat cttgaggaaa gatgccgctg
    17101 gtaaaagcgg aaagtcaaag tacatcagca caaatgagat ggctgataaa attgcaatgg
    17161 tcgaaagtcg acgtgtgttt gtcataacag gttcctccaa ttttctataa aatcagaaga
    17221 agttggaaag gattcctcta tctattctca ctttttatat cccaaaagtt ccctcttact
    17281 ctattaaaga aaaacaaagc aagtggttac aatccggcta taaatctatc aaaacagaca
    17341 aagctattct ttcgtcttct cccatccaga ctatactgtc ggttgtggaa tctcaccaca
    17401 tcagcttgcg ctcgcggact tctttaaaga gaaggaaata gagatttttc ttttagacta
    17461 ggcgacaagc tgtaggcata acttctggtt aggcaaagct tgtcaacaaa gtataaaagg
    17521 aaaagatcat ttcctagtta aagtcaccgc cggtcgggaa tcacaccctg ccctgaagac
    17581 tcttttatca taacaaaaaa cgcttgcaag cgcaagcatt ttgttcattt tcatttttta
    17641 tttcaattta tccacttcat aggtatggac gagctcaaga cctgcaaagt tctgctggcg
    17701 aagagcctca tagacaatca tgcagacggt attagacaca ttgagactgc ggacatgttc
    17761 atcattcatg ggaatacgga gagccttctc aggatgttct cgcataaaat cttcaggtaa
    17821 gcccttgtct tcacgtccaa agagaaaata atggtcctcg tcagtcgata aatccacctc
    17881 agaatagact ttttccgcga atttcgaaat cagatagagt tttcccttca tctgagatat
    17941 gaaatcttcc aaactctcgt aaaaataaat ctctagctta tcccagtaat ccaatccagc
    18001 ccgcttcatc ttgcggtcat caataggaaa gcccataggc ttgatgatgt ggaggggaga
    18061 attggtcgca gcgcaagtac gcgcgatatt gcccgtattt tgtggaattt gaggttcaaa
    18121 taatacaatg tgatttgtca tgacttgctt cctttcacca ttgcaaaaaa atagccacac
    18181 tgcccggagt caagctcagc aaacagcgtg gttaaggcat cgttaactta cctcacaaca
    18241 ggtttgaagt aaatcagcga aactactttc ttagtataac actttcagaa tcattgtcaa
    18301 tagaaatgac ttgatttttt caattttttc aagctatttc caagggttgt aaaatcgtcc
    18361 ctgattctgc aagataagta gtaaactaac tactaaaaac aaggttgcca agagcaaggt
    18421 aatatagtct ccttttttca aggcctgata actataccat gtgcgttttt tctctttccc
    18481 aaagcggcga agctccatgg cagtcgcaat ggtatcaatg cgttctagcg agctaaaaat
    18541 caagggcgta ataatgagca gattgccttt gattcgttgc ataagagaag ctttcttgga
    18601 taattccatc ccacgcgcct cctgagacat cttgatagta aagaattctt cctgcaaatc
    18661 tggaatatag cgcaaggtca ggctgacaga ataagcaatc ttatagggca caccaatttg
    18721 atttaaactg gaagcaaact gactaggatg ggttgtcatc aaaaagataa tagccagagg
    18781 aatggtgcaa agatacttaa tggccaaatt tagcagataa aagagctcct ggctggttag
    18841 agtgtagaca ccgattccct gccaaatcac acttctctct ccataaagtc caaccccata
    18901 ctcgggagaa aagagataga ccatcaaaac gtttaaaacg gcaaataccg tcgcaaaaac
    18961 ggctacaaag gaaacatctt taaagcgaat ttctgataaa tagaggagaa agactgaaaa
    19021 gatggcaatc agcaagagca ttctggtatc atagctaatc atggccgcca atgataccag
    19081 aatgaaaaag agaagtttcc cagctcctga caagcgatga atcacagtat ctctatgctg
    19141 gtaaccgatt aatttagctt gcatccctct ctcctttctt tgtaaaatgc cgttaaatcc
    19201 agtggatcca catctagttt cttagccaag ttaaagatgg aggtttcttt tagattggct
    19261 tttactaaca gctcaggatc gctcaacaga ctggctggaa cagtatcggc aatcaattct
    19321 ccatccacca tgacaaggac tcgatctgaa taatccagca tcaattgcat atcatgggta
    19381 atcatgacaa tggtatgccc ttgttgatgc agttcttcga gaaattccat aatctcagta
    19441 tagttcttct ggtcttgacc cgcagtcggt tcatctagga ggataatttc agcgcctaag
    19501 accaaaattg aggcaatagt cacacgtttt ttctgaccaa atgacagggc agaaatgggc
    19561 caattacgga attcatagag accacagatt ttcaaggttt catagactct cgtttcaatt
    19621 tcctgctcgt ccacacctcg caaacggagt cccagagcca cctcatcaaa aatcatattg
    19681 gttgaaatca tttgattggg attttgcagc acatagccta ctcgttccgc ccgctctgca
    19741 acagaatctc cttttatatc ctgtccttcc caaagatagc ggccttcagt ctggataaag
    19801 ctactcaagg ccttggctag agttgacttc cctgctccat tttttccgac aatagcaatc
    19861 ttttcaccct ttttaatatc taaatgtagg gattttaaaa tcggtctatc atcataagag
    19921 aaagacacgt cctctaattt aaagagtgac tgcaattctg gagtttcttt tgccagttca
    19981 ttctgcagct gaacctgacc ttttgagata gacatgttat ccagattcgc taactgttct
    20041 tccttgacta agtccacacc taattgacgg agagtcgtta gataaagggg ttctcgaatt
    20101 ccattttgag tcaataaatc agtcgcaagc aactggtcag ggctcccatt aaaaaggata
    20161 cgaccatcgt ttatcaagac aatccgatcc acagggcgat gcagaacatc ctccaaacgg
    20221 tgctcgataa tcagagtcgt cgtcccctct tccttatgaa tctggtcaat caattcgata
    20281 atatcctgac ctgatttggg atctagattg gcgagtggct catcaaacaa gagaatcgga
    20341 ctttcatcaa tcaagacacc agccagactg actcgctgct tttgtccacc tgacaaatcc
    20401 tgaggacgct gatccagtaa aggaagaagg tccagctttt cagcccattt ataaacacga
    20461 cctttcatct catctagggc tgtcacatca ttttccagag caaacgccaa atcttctgcc
    20521 acagacaagc caataaactg cccatctgta tcctgcaaaa ctgtgctaac cagatgagac
    20581 ttatcataga tgctcatatc aaaggctact tgacccttta tcaaaaattc tccatatgtc
    20641 tgacccttgt aaatattggg aataatccca ttcaaacact gacccaaggt agatttacct
    20701 gacccagatg gtccaacaat taagactttc tctcccttgt aaatggtcaa gtctatccct
    20761 tgcaaggtcg gttcttgttg tgtttcatac cggaaagaga aatccttcca ctcaattata
    20821 gcttctttca tcttactctc ttcattcgct tcttagactt ctattttatc ataaatcaag
    20881 cccttcttgc agtctcttct cttaaaatct tagcgccaaa aagattccta tcctagctta
    20941 cttgcctaac taatctataa acatcgaaaa agactagttg cccagccttc cccatcattt
    21001 tatactcttc gaaaatctct tcaaaccacg tcagcttcgc cttgccgtag gtatggtt
//
LOCUS       DAVHSL010000038        20887 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000038 DAVHSL010000000
VERSION     DAVHSL010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.039"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            354..1307
                     /locus_tag="VVR39_001451"
     CDS             354..1307
                     /locus_tag="VVR39_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU6030919.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIKRWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRG
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            1628..1762
                     /locus_tag="VVR39_001452"
                     /pseudo
     CDS             1628..1762
                     /locus_tag="VVR39_001452"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2000..3261)
                     /locus_tag="VVR39_001453"
                     /pseudo
     CDS             complement(2000..3261)
                     /locus_tag="VVR39_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3268..3729)
                     /locus_tag="VVR39_001454"
                     /pseudo
     CDS             complement(3268..3729)
                     /locus_tag="VVR39_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
     gene            complement(3732..4334)
                     /locus_tag="VVR39_001455"
     CDS             complement(3732..4334)
                     /locus_tag="VVR39_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003094863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030920.1"
                     /translation="MSNIKAKINSKIDNLPDGAVFISNDFLELADYETIRKNLNRFVN
                     EGTIQRIVNGVYYKPRFIELIGEYESPSINEVAIAIARKYNWTIAPSGNTALNLLGLS
                     TQVPAQWTYISDGRYVNFIIGNTKLVFKRTTNSTISNMSQLTALVIQAIKAIGKDNIS
                     EEQILYLKNRLTISDKEKLLEEGKATSAWIYKVLKKIGES"
     gene            complement(4402..7203)
                     /locus_tag="VVR39_001456"
     CDS             complement(4402..7203)
                     /locus_tag="VVR39_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6030921.1"
                     /translation="MKEDKKLVKQARQNFRSNLKSARMHYRKEVRTLKQTVPKKGRFR
                     KPAQNSLFQDKKTELKQNLLGSQKEAEEKFLKEITYVSPRLLRVKEIKNYRLPQAQER
                     LRTAKKQLSEVKLDEKQKAVNPKFLFQKENPSSKSHFQFHQEKSFDRLSAEKEVRSAK
                     REVKQLKKVRKSKKNSTKVKGGLGLAISESLDLVAQDDDLDGLRTIKDTSLKARRYGR
                     FTYQAGKVAVKSGQTSVRFTKTKVAHGKERFHNFKKGKGFTRQKPLKSRRRYQTFLKH
                     ARKHSLAGIKGIAQAIKGSLTFFSAIAGNPLTWIVSGILLILLLMMSFFMSVSGSSVI
                     QQDEMELTKAYTHMTWEDAEHTRTNEKGITYYTKVDDVMVYMNHQYQDYKLDDVKETG
                     GAIYKAFLSQVWTDLNGGDSIKSMSDLYKEPSYKLSDEDQEELKELTEEGNYLALQEL
                     DNPFQGQTDEDSLNMSYRYGYEVIDEKPTLHHHIILEAKEDQVIVAPMDGKVSLDGEN
                     VILTSGKGVNRTKLTLFGIHSGRVSENQQVLAGDIIGQNKDGTGLKVTYQKVDDDTDK
                     LVYVNPAFYFPKVIQVQTTILPTIGQFGGDEFERAKAIYDYLKSEGATNQAIAAILGN
                     WSVESSINPKRAEGDYLSPPIGATDSSWDDEGWLSLNGPTIYNGRYPNILKRGLGLGQ
                     WTDTADGSRRHTLLLEYAKGKHQKWYDLGLQLDFMLHGDSPYYSNWLKDFFKNSGSPA
                     SLAQLFLIYWEGNSGDKLIERQTRATEWFYQIEKGFSQPNGGTAQSDPKSLEAVRGDL
                     FENSIPRGGDGMGYAYGQCTWGVAARINQLGLKLKGKNGEKIPIISTMGNGQDWVRTA
                     ASLGGETGTIPQAGAILSFAGGGHGTPTEYGHVAFIEKVYPDGSFLISETNYNGNPNY
                     TFRKLSGVDSSLSFAYTTK"
     gene            complement(7205..9530)
                     /locus_tag="VVR39_001457"
                     /pseudo
     CDS             complement(7205..9530)
                     /locus_tag="VVR39_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734154.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(9487..9840)
                     /locus_tag="VVR39_001458"
     CDS             complement(9487..9840)
                     /locus_tag="VVR39_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU6030922.1"
                     /translation="MNTRVFKDISKVQHRAWLGFTTRQVVFVFPAVAITIMVLGLNLF
                     YWQFGDWFVYGFVFSFTIPLMLFGVYRPNDLPFETYLKYRFHYELTVPDRTFTGRKGD
                     QREKIKPLNETKDLF"
     gene            complement(9902..10756)
                     /locus_tag="VVR39_001459"
     CDS             complement(9902..10756)
                     /locus_tag="VVR39_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU6030923.1"
                     /translation="MMMNFTSPFVFLASEKVSSDSLFEGFQVDLETTANLVKSLADFN
                     PTVWSYMTAITKGIMQPLGVAILAVVLVLEFSKMAKKIANSGGAMTFEAIAPMIVSYI
                     MVAVVITNTTVIVEAIIALASYVIEQVAGLVTNGGASYDTISGIKGSGIVGKMIIGFF
                     AILIWLVRMVSIMVVNILITIRFIQLYLMIPFAPVTIPTFLSDDWRSVGIGYLKNIMV
                     YAVQGILIFLIVSLVPLFESAGKIAVSNGAGVMESLAIMFGGLVQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(10775..11017)
                     /locus_tag="VVR39_001460"
     CDS             complement(10775..11017)
                     /locus_tag="VVR39_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030924.1"
                     /translation="MNQKLTGFVYGVDASPMFSQAMSLLQKGLIAVGAFLVVMGIINL
                     STNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQITI"
     gene            complement(11035..12816)
                     /locus_tag="VVR39_001461"
     CDS             complement(11035..12816)
                     /locus_tag="VVR39_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU6030925.1"
                     /translation="MGLAFGYFCHRLTLLYDSLTNAPPMERFAYLLGEGLNQVFNPLW
                     LFSFTRKSLLAFILGVITMSLVYLYVSTGQKVYREGEEYGSARFGTSKEKRFFYSKNP
                     FNDTILTRDVRLTLLEKKKPQFDRNKNLIVIGGSGAGKTFRFVKPNLIQLNCSNIVVD
                     PKDHLAEKTGKLFLENGYQVKVLDLVNMTNSDGFNPFRYVETENDLNRMLTVYFNNTK
                     GNGSRSDPFWDEASMTLVRAIASYLVDFYNPPGSSKQEQEARRKRGRYPAFSEIGKLI
                     KLLSKGDNQDKSVLEVLFEDYAKKYGHENFTMRNWADFQNYKDKTLDSVIAVTTAKFA
                     LFNIQSVIDLTQRDTMDLKTWGTQKTMVYLVIPDNDTTFRFLSALFFSTVFSTLTRQA
                     DVDFKGQLPIHVRSYLDEFANVGEIPDFAEQTSTVRSRNMSLVPILQNIAQLQGLYKE
                     KEAWKTILGNCDSLLYLGGNDEETFKFMSGLLGKQTIDVRSTSRSFGQTGSSSTSHQK
                     IARDLMTADEVGNMKRDECLVRIAGVLVFRTKKYFPLKHKNWKWLADKESDERWWHYH
                     INPLITEEEIDLSGHTIRDLSTEMSIY"
     gene            complement(12852..13340)
                     /locus_tag="VVR39_001462"
     CDS             complement(12852..13340)
                     /locus_tag="VVR39_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030926.1"
                     /translation="MSSEQQERQAMQYVERSSLFTVRTLLKLLEWSARQALAQDSAYK
                     IGVQKLEELLQSPYAIEAIDVSKDILDKPIDVEKFKELMESEKLPIAISWQKDYLYFY
                     AKDKTLLDHHLDELLKKLMSNPEKLEGLTFDKSLDQEIELAKEKIKVTEPSVVRTKEV
                     TL"
     gene            complement(13417..14001)
                     /locus_tag="VVR39_001463"
     CDS             complement(13417..14001)
                     /locus_tag="VVR39_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6030927.1"
                     /translation="MIRIVLFYLAIQLNGLLVSLYLHDYMTIKVLILLQTLLLGVACL
                     EITHHKTVQAKNITLQNRLRWLLLGFACMVSFAVLISFLFPVQTRNQSVLVEVGKQVP
                     HVIFLLFLVNASVLEEIVYRQLLWEKLTFPFVQIGVTSFLFSLAHGSNQLGSWLMYSC
                     LGVTLAVVRLKTDCMTAMTLHLLWNSLVYVLTFL"
     gene            complement(14004..14237)
                     /locus_tag="VVR39_001464"
     CDS             complement(14004..14237)
                     /locus_tag="VVR39_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6030928.1"
                     /translation="MNERFWDNLEIILAEKELTWAELARKVFKGQYVYPSEFNRLYQK
                     LRHYKSNRLMPQTRWVERIVLVLDIDYEDLFKR"
     gene            complement(14246..14629)
                     /locus_tag="VVR39_001465"
     CDS             complement(14246..14629)
                     /locus_tag="VVR39_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030929.1"
                     /translation="MLEVYLGNNDNTNRDLLTILTTYGVTYRCTKACDVNREIILSLF
                     AKTMDCFELLSPRFLRFKRQYTISLNEMIQLILQKPDQNLRLPLIVCQNHVYPAIGLD
                     EVRTFLPRQVKEELFQASLMTQVTG"
     gene            complement(14640..15068)
                     /locus_tag="VVR39_001466"
     CDS             complement(14640..15068)
                     /locus_tag="VVR39_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030930.1"
                     /translation="MNLLHKKSILECTELEERIHQVEINQLLQKILSLPNFDCDFEVT
                     FEDDYHKEMNDPLFYESNLHRISDFLETRDIKNGVDTLLTKDNHLAFRAFGQNYTARG
                     KDGILTTLVTVKCSGEGRMPVDMSHYFSTPEPTVENSLTL"
     gene            complement(15052..16407)
                     /gene="dcm"
                     /locus_tag="VVR39_001467"
     CDS             complement(15052..16407)
                     /gene="dcm"
                     /locus_tag="VVR39_001467"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU6030931.1"
                     /translation="MKFLDLFAGIGGFRLGMEAQGHECLGFCEIDKFARTSYKAMFKT
                     EEEIEYHDIKEVTDHDIRQFRGQVDVICGGFPCQAFSLAGRRLGFEDTRGTLFFEIVR
                     CAKQIQPRFLFLENVKGLLNHDEGRTFATILSTLDELGYDVEWQVLNSKDFQVPQNRE
                     RVFIIGHSRRYRSRFLFPLRRENSPAHLERLGNINPSKRGLNGEVYLTTGLAPTLTRG
                     KGEGAKIAIPVLTPDRLEKRQHGRRFKDNQDPMFTLTSQDRHGVVVAGNLPTSFDQTG
                     RVFDIAGLSPTLTTMQGGDKVPKILLREELPFLKIKEATKRGYAKATLGDSVNLAYPD
                     STKRRGRVGKGISNTLTTSDNMGVVVAAMEYRQDKWYEVTGIVLDGKLYRLRIRRLTP
                     RECFRLQGFPDWAYERAESVSSKSQLYKQAGNSVTVTVIEAIAREFRRMEEEEKHEPT
                     T"
     gene            complement(16565..17374)
                     /locus_tag="VVR39_001468"
     CDS             complement(16565..17374)
                     /locus_tag="VVR39_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6030932.1"
                     /translation="MKRITANQYQTSERYYKLPKILFESERYKDMKLEVKVAYAVLKD
                     RLELSLSKGWIDEDGAIYLIYSNSNLMALLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHESIPVLDSDGASVKKTLGGAQKKTGPVLNSAPSETEGNETEY
                     SETEGSDFLIEDEEERQLVDDKQEENFSSKVDAVTKYDRDYIWDLVHDQLRQTGLSQS
                     ASDYAMIYFSERYQYALEHMRFARSAEVIAEYVFNGVLSEWTKQLRRQEVR"
     gene            complement(17371..17544)
                     /locus_tag="VVR39_001469"
     CDS             complement(17371..17544)
                     /locus_tag="VVR39_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030933.1"
                     /translation="MQKYEQSSRQLVMCQLMAIMGVDIVKATQLIDEMEQVGLIQFDE
                     FGNVGILVLEGQS"
     gene            complement(17622..19556)
                     /locus_tag="VVR39_001470"
     CDS             complement(17622..19556)
                     /locus_tag="VVR39_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6030934.1"
                     /translation="MKKEVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQIN
                     SYNSQVEHYTEFIQKNNEWTLAGIYADEAITGTQVDRRIDFQRLINDCMNGDIDMIIT
                     KSISRFARNTLDTLKYVRKLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVEN
                     ISANVKKGLRMKMERGEMVGFQGCLGYDYDPETKSISINEKEAEIVRYIFRRYIEGVG
                     GMVISRELEEQGYLSPRGNKRWTETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDN
                     FGEQDKFYIENHHEPIISEEDFEKAQGIRLRRSKNRNTVANNGGKREKYSRKYAFSSM
                     LECGFCGHNLSRRNWHSSSEYTKVIWQCVNATKNGKKYCPHSKGIEEEAIEKAFMESY
                     RQVCHNNVEITNEFLKTVEEELKDNSLAKDLKKITNQLDRILKKEKDLVELRLNESIS
                     MDIYQDKYNEIAISKEKLLAEKRTLEVTLTDEKALKKRLEGFKKLLESNKYLEEFDRA
                     VFESIVDKIIIGGTNDEGEIDPAMITIIYKTGKKDSQDGRLFKSRRKNAKEVNEKADS
                     KLYPQSSDEVNNLCSYPMDNTRGVRSIATTKKRVKILYFKHFFKHFVFIEKSDFDIKK
                     VQKKYIDVNVCLDVDCVDKK"
     gene            complement(20221..20631)
                     /locus_tag="VVR39_001471"
     CDS             complement(20221..20631)
                     /locus_tag="VVR39_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6030935.1"
                     /translation="MPKEYYLYVNGQRVKVSEQIYKVYWREREHEKYLEQVDRKNHLL
                     FFSSLDHDGHFVDNIVDESVDVEKIVETQMMIEAVRNAISRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
BASE COUNT         6011 a         4490 c         3645 g         6741 t
ORIGIN      
        1 gaacaagtct agtataattt taccacaaag taacatgatt tgcaagcgat ttcaataata
       61 aagatatatg attatcctca ggaataaata aatttgaaag ttctataatg aagttagcca
      121 ccttacctta gtcaagaatt agatgtttca ctatgtttga gtaagttgat gatttcattt
      181 gataacaggt ttgaaactgt taggctaggt ggccaaggct aatcatagcc ttggtttagc
      241 tgaaaaaaca ggttcaaggg ttcctgttgt caaatgaaat gtgatttaag gtataagaaa
      301 acacctctgt gctatacttg ttgttcacca caaacacaag gaaaggcaca gagatgcaag
      361 aacattatac cccaaaaggg aaacatttga caatagataa ccgtcgcttg attaagcggt
      421 ggaagaatga aaataagtcc aatcgtgaaa ttgcaggctt gttaggaaag gcgcctcaaa
      481 cgattcataa tgaagtcaaa agaggtacaa ctttacaaca agtgagaaaa gggctataca
      541 aaaaggtcta ttctgccgat tacgcacaaa ctgtttacca attcaatcga aaacggtcgg
      601 tgaaaaagtt aattttaaca aaggaaatca gagagaagat cttacactat cataagcaaa
      661 aattttcgcc tgaaatgatg gttaacaaga agcaagtgaa agttggtatt tcaaccatct
      721 actactggtt tcataatggt catttaggat tgacgaaggc cgacatgctt tatcccagaa
      781 aaaggaaagg tgtcaagaag caagctagtc cgaactttaa gccggcaggt aaatctatcg
      841 aagaacgtcc tgacgttatt aatcttcgct tggaaaatgg tcattatgaa attgataccg
      901 tcctactgac taagataaaa aattattgcc tgttagtctt aaccgaccgg cggagcagac
      961 accaaattat aaggttaatt ccaaataaaa ctgctgaatc tgtcaatcag gcgcttacgt
     1021 tactattagg ggagcatcgt attctgtcca ttactgcaga taatggttcg gagttcaaac
     1081 gattgtctga ggtatttcct gaggaacata tctactacgc acatgcttac tcttcatggg
     1141 agagaggttc aaatgaaaat cataatcgat taattcgggg atggttacct aaaggaacca
     1201 agaaaacgac tccgaaagaa gtagctttta tcgaaaattg gattaacaac taccctaaaa
     1261 aatgcttgga ctacaagtcg ccaagtgaat ttcttttggg tggctaactt caacttgaaa
     1321 tttgggcttt gtctctatgc taaaggaatc cgctataaat acaagtacta tagccgtcgg
     1381 cattcctcat taacacgacc caatttgatt aatcagtgtt ttcaaacaaa aggtaaaaat
     1441 gaaatctggc tgggggattt aacttatatt ccgacaaaag caggtactct ttatttatca
     1501 ttatatatat gtttatagca gaaaaattgt tggttaggca atgggaaatc gaatgcaaga
     1561 taagttggta acgaatgttt tcaatcaagc ttatcataga gaaaatctca aataagaact
     1621 agtcggccat accgatcaag gatctcaata tactggagct agatttcaag aactccttaa
     1681 acagaaaaga tgcaagtcta gcctgagtcg aaaaggcaat ccatatgata atgcacccat
     1741 ggaatccttt tacaaaacat aaaaagagaa cttgtcaatg atgccaattt cgcaactatt
     1801 gaacgaaatc tttaaatata ttgaaatcta ttacaatcct aaatatctcc attcggcatt
     1861 agggtaccaa taactaatag agtttgaaaa aaatagtcac taatcatcga gtccactgaa
     1921 aaagtaagct ctacagttca actaaaatga aaaaagaggg atctatctcc tgcttggata
     1981 gattcctctt tgcttttcct tatttttggt ttattagagt tataatcctc ttcatattaa
     2041 ccacaaatat ggttgtggcg gcttgtaact ccatgtttaa aagacctggt gctctagcta
     2101 cattaagacc atgtctgttt tcaagttccg catttttggc ttctatcttg tagcgatgtt
     2161 tggccttttc tttaaaatag ggcgcttcct gaaacctctt ctggaaaata tgttcatcgc
     2221 tcttaagggg tatcaaataa gtcttagact tagccccttc tttataacag cccacttttg
     2281 aagggcatat ttgacagtgc ttgatgtcaa aatagtgggt ttcctgagcc gtccttcttc
     2341 ctgtctttgc cttctttagt gccatatgcc cttctggaca aacaaagaga cctgcgtcct
     2401 tgttatagaa aaactcatct tccttcctac gaaagccttt tgaaatagtt ggatatggcc
     2461 tagcgactca atgcacacgt tctttcttgg taaattgcat attatccttc ccagagtagg
     2521 ccctatctcc aacaatagct tcaatcgtca cgccattatc cttagatttg tgatagagtt
     2581 cttctaaaac aggaccatca cttttttcac ccgatgtcac cacacaggca gtaataatcc
     2641 gttcatcggt catggcaaaa tgctctttgt acccgtaaaa ggaactatcg gctgacttat
     2701 gtccaattct tgcttcttct ttgacagagg attccaagtg ctctaagtca tcctctacag
     2761 cttctttaag gtaattgaat tttgtgagat agctggtatt ccagtcaatt cgtcatgctt
     2821 ctcaaggact gatattaatt cttgtgtata tcttaattca gctactagag tatcttcctg
     2881 aggcttacta ggaaattctg ccttgatata ttccgaatac tgataaatcg ttttacgcaa
     2941 ggcttttgag cgttctcgga ggacttcttg aggtttcttg tgattgtaat gaactttggt
     3001 atgagtcgca tccacaatga gaatgttact tttaatcaga ccgagctcta tcgcaatctg
     3061 aacagattta gcgatgagca aatcaagtaa tcgttcatct ttgttccgaa gttttcggaa
     3121 tttagtcaat gaggacggtt caataacagg agctagacca aggaagtatt tgaaggtcat
     3181 accagaaaag gagcgctcca ccacatccac atcggacaac ttatagatgt cttttaataa
     3241 gagatacttg aacatcatga taaggagaga ggttggatat tcaaaaagta ctgtttgtgg
     3301 gtcattttca tcaacactaa tttgaaaatc atcttcaatt aaattcgcaa aatctatcct
     3361 catctgcgga attaatgcat tcacaagaaa gtcttctgct tttaaatttg attccttatt
     3421 gaacttatct tgttgcgtat tagaacgaga ttgccatggt tcgtctttac catatccaat
     3481 tacctgccaa tccaagatta aatcaatatc ttctgaaaat cgcttaatta aatcatagca
     3541 cttagaaaga cttgtgcccc ctttaaatgt aaatgcatcc ttccattcac tctttgtaaa
     3601 gagatagttg agtacaaaac aaacccaata gtctttctca acaatcactt cattgatacc
     3661 aagtctttcc gaagcatttc taataatggc ttgaaggtct tctttggaaa tttttttaaa
     3721 ttctagcatc tttaggattc tcctattttt ttcaagactt tataaatcca ggcactggta
     3781 gccttgcctt cctcaagaag tttttcttta tcacttatag ttaacctatt cttaagatat
     3841 aaaatctgtt cttctgaaat attatctttt ccaatagctt tgatggcttg aataactagc
     3901 gcagttaatt gcgacatatt tgaaatggta ctatttgttg ttcgcttgaa cacaagtttc
     3961 gtatttccaa ttataaaatt tacataccgt ccatcagaaa tataagtcca ttgagctgga
     4021 acttgtgtcg acaaccctaa taaatttaga gctgtgttac ctgaaggtgc aattgtccaa
     4081 ttatattttc tagcaatggc aatagccact tcatttattg aaggagactc atattctcca
     4141 atcaactcaa taaaccttgg tttgtaatat acaccgttta caattcgttg aatcgttcct
     4201 tcgttaacaa atcgattcaa gttttttcta atggtctcat aatcagcaag ctctagaaaa
     4261 tcatttgaaa taaagactgc gccatctggt agattatcaa tcttactatt tattttagct
     4321 tttatgttac tcaattcctc accaccttgt cccaaatatt atacaacatt tgggacaaaa
     4381 tgacaactat ctttctgtct attatttcgt cgtatacgca aaactcaagc tgctatccac
     4441 tccagataat ttacggaagg tatagttggg attgccattg taattggttt cggagataag
     4501 gaatgagcca tctgggtaaa ctttctcgat aaaagccaca tgtccgtatt ctgtcggtgt
     4561 gccatgtcct cctcccgcaa aagagagaat agctcctgct tgtggaattg tgcctgtttc
     4621 accaccaagg cttgcggctg tacgcaccca atcctggcca ttacccatgg tactgataat
     4681 cggaatcttc tcaccatttt tacctttgag ttttaaaccc agttggttga tacgggctgc
     4741 gactccccaa gtacattggc cgtaagcata acccataccg tcaccacctc ttggaataga
     4801 gttctcaaag aggtctccac gtacagcttc aagagatttt ggatcgcttt gtgccgtccc
     4861 accatttggc tggctaaagc ctttttcaat ttgatagaac cactcggtcg ctcttgtttg
     4921 tcgctctatg agtttatctc ctgaattgcc ttcccagtaa atcagaaaga gttgggcaag
     4981 actggctgga ctacctgaat ttttgaagaa gtcctttaac caattggaat aataaggact
     5041 atccccatgc aacatgaagt ccagttgtaa ccccaaatca taccactttt gatgttttcc
     5101 tttggcatat tccagcaaca aggtatgtct gcgtgaccca tctgcggtat ccgtccattg
     5161 tcctaagccc aaaccacgtt tgagaatatt tgggtaacgt ccattgtata tagttggacc
     5221 attaagtgag agccatccct catcatccca cgagctgtct gtcgcaccaa tagggggaga
     5281 tagatagtcg ccctccgcac gttttggatt aattgaggat tctaccgacc aatttcctaa
     5341 gatagctgcg atagcttgat tggtcgcacc ctcacttttg agatagtcat aaatcgcctt
     5401 ggctctctca aactcatcac caccaaactg accgatagtt ggaagaatgg tggtctgaac
     5461 ctggatcact tttggaaagt agaaagctgg attaacatag accaacttat ccgtgtcatc
     5521 atcaaccttc tgataggtga cttttaggcc cgttccatcc ttgttttgac caataatgtc
     5581 tcctgccaag acttgttgat tttcacttac tctacctgaa tgaatgccaa acaaggttag
     5641 tttagtccta ttcactccct taccagatgt cagaataacg ttctctccat caagagatac
     5701 cttaccatcc atcggagcca caatgacttg gtcttctttt gcttctaaga taatatggtg
     5761 atgaagtgtt ggtttctcat caatgacctc ataaccatat cggtaggaca tgtttaagct
     5821 atcctcatcc gtctgtccct gaaagggatt gtccaattct tgaagggcta aatagttgcc
     5881 ttcttcggtc aactccttta gttcttcctg gtcctcatca gacagcttgt agctaggttc
     5941 tttatacagg tcagacatgg atttaataga atcaccacca tttaagtctg tccacacttg
     6001 actgagaaat gctttgtaaa tcgcaccacc tgtttcctta acatcatcta acttgtaatc
     6061 ttgatattga tgattcatat agaccataac gtcatcaacc ttggtgtaat aggtaatccc
     6121 tttttcgttg gttcttgtat gctccgcatc ttcccacgtc atgtgggtat aggccttggt
     6181 caactccatc tcatcttgtt gaatgacact gcttcctgaa acactcatga aaaagctcat
     6241 catcaaaagg agtatcaaga gaatgcctga gacaatccaa gtcaaaggat ttcccgcaat
     6301 tgcagaaaag aaggtcagac ttcctttaat ggcttgggca atccccttaa ttcctgctag
     6361 actgtgcttt ctggcatgct ttaaaaaggt ttggtagcgt cttcttgatt taagcggttt
     6421 ctggcgtgtg aatccttttc cctttttgaa gttgtggaat cgttcctttc catgagcgac
     6481 tttggtcttt gtaaaacgca cactagtctg tccacttttc accgccactt taccagcttg
     6541 ataggtaaat ctgccatagc gtctggcttt caaactagta tcctttatgg ttcttagacc
     6601 atctagatca tcatcctgtg ctaccaggtc aagcgattca gatatagcta agcctaatcc
     6661 acctttaacc ttggtagagt ttttcttaga ctttcggact ttcttgagtt gtttgacctc
     6721 acgtttggca gacctcactt ctttttcagc acttagtcga tcaaatgatt tttcttggtg
     6781 aaattgaaaa tgagacttcg aggaagggtt ttctttttgg aagagaaact tgggattgac
     6841 cgccttttgt ttctcatcta gcttcacttc tgacaattgt ttttttgccg tccgcaaacg
     6901 ctcttgggct tggggaagtc gataattctt aatttccttt acccttaaca gtctaggaga
     6961 cacataggta atttccttta gaaacttctc ttctgcttcc ttttggctac ctagcaaatt
     7021 ttgttttaac tctgttttct tatcttgaaa cagagaattt tgggctggtt ttcgaaatcg
     7081 tcctttttta ggaacagtct gttttaaggt cctaacttct ttccgataat gcatacgagc
     7141 tgattttaag ttgcttcgaa agttttgcct agcttgtttg actagctttt tatcctcttt
     7201 catctcatgt cctcattttt tcagggtctg tactcatgat gtcaaagagc ttggtgtgtt
     7261 gtggaatctt attcttaaac gggacaacgg tggaaccggc cttgattagg ccagcacctt
     7321 tttcaggatt gaccaagtat ttctctagtt ccttggaaag tccaagcaaa tgcaccaact
     7381 cttcgcgatc gctcttagcc tgttttaata gaatcatgaa ctcgctattg gcaataatac
     7441 gtctgccatt ggcatccaaa agaagtgtct ccacattctg agtaatgcca gttggtatcg
     7501 ccccatactt acggacacga ctccagagtt taaagaagaa atcagaggca tatttgtcca
     7561 ataagagaag ctgcatttca tcaaagtaaa tccaggtctt cttccctagt ttttggtttt
     7621 tcaccacacg attccaaatc tggtcaaaga taaccatgag ggcaatttgt tttaattcat
     7681 cgcctagctt tttgacattg taaatcagaa aatgactatc tgtcttgata ttggtccgat
     7741 gcgagaaaat atctagcgat ccttccacat agagttccat atacagtgcc aagttcttag
     7801 cttcctgttc aggttgttga gataagacaa agacccattc gaccaaagat ggtgtatcaa
     7861 aatgcttata ggtaagtcgt gtcacacggt caatcagcga cttttcgcga ccatccattt
     7921 tgcggtccaa gagctttcca atccaagaca agaggaattc ggatttaacc ttgactggat
     7981 cctcatccat attctcatcg gatagttcta aaacatttaa gaaggtagtg gaatctggtg
     8041 caatatcaat actttctcca ccaaaggctt gaccgataat gctgtactca ttttctgggt
     8101 caacaataat aatttcggta tcgctatctg cttccttgag cttagtagag atgatttcat
     8161 gttttgtcgc catccctttt ccagctccag aagtccctaa aatcaaacct gacggagtat
     8221 ttaacttgcc acggtcaata ctgatgatat tacttgagat ttgattgatg ccataaaatt
     8281 tcccaccctt gtcctgaata tcaacggaag tccaaggtgc attcacggca atgtttgaag
     8341 tcaatagaga acgagaaact ccttcgagat agttcttccc aaatggcaag agactattaa
     8401 aagcagcttc ttgcatgtag gtcaagttgt caataatcat atcatttgac cccgccactt
     8461 gcttgataat atcaagggct tgtttgagtt ggtcttcagt atccgccagc acgccaatta
     8521 gaaatacggt gtcaaacagt ttatctcctg tttgggtcat ggtttgaaga agagcttctg
     8581 cttcatcgat attgttttca agaacatggc cgaccttctc caaatagatg ccagtccgag
     8641 ccatcttttg ttgttcccca atcttttgcg attccatcaa ggttttcttg gttcgtaact
     8701 tagtcatagc ttcagactta gttgagcctt tggcgtgtag gctaatcatc acttccaaat
     8761 ctatccccta gctccatacc gtaatcacga acatagacaa tctgtaataa tctatcgtcc
     8821 aattcaatat gattcttgtg tttaaaggaa aggtaggttg gcgcaataaa gtgtttggtg
     8881 gattgacctg acagggttaa atccttgtaa gagaatggta aatgattttc acctcgtaac
     8941 atatccgcaa ggacattcac tcgctcctct ccatcaagta aaccaagaga tacatcaatc
     9001 tctgaaaagc cactcttgaa atattcccca atctgtgaca gggaacgaaa agctagtttt
     9061 ggtgtttggt cgctcttgcc aaatgaaagc aacttgacag ctgaaaagtt attctcaccc
     9121 gcttctaagt tggcatccat catgcgattc aattcatcac ggtagccatc aaacccatct
     9181 tcctgtaagg gatagagaat actcttacga aatttttcca gattgacttt ttgattgaaa
     9241 atagtcagtt ggaaattggt cttatcgtcc agtgaattga ttaaatcaga atatttctcc
     9301 acaatagctc ccttatcgtc taagccaact gtttggtaat tgacatctcc taagagatag
     9361 gtttgtgaaa aatggcttgg gctgacctgc atgagtccat tttgaaagag accttgatag
     9421 gctaacgtat ttagggtaga aggtctgatc tcctgcttct gtgttttcgt cttttgctta
     9481 ttgtcattag aagaggtctt ttgtttcatt aagtggttta attttttcac gttggtctcc
     9541 ttttcttcca gtaaatgtgc ggtctggcac cgttagttca taatgaaaac gatacttgag
     9601 ataggtttca aatggtaaat cattgggtcg atagacccca aataacatga gtggaatggt
     9661 aaagctaaaa acaaaaccat agacaaacca atccccaaat tgccagtaaa ataggttcaa
     9721 gcccaatacc ataatagtta ttgcaacggc tggaaataca aaaacaacct gtcttgtggt
     9781 aaatcccaac catgcacggt gttgaacctt agaaatgtcc ttaaagacac gagtgttcat
     9841 aaatgttctc caatctagat aagctataaa aagaggaggc gggcaattta ctcccatcct
     9901 cctacatccc caaaatactt cgggcggttc gttgactgcc aactaaggca atgattaaca
     9961 agatggcctg taccaaacca ccaaacataa tggcgagtga ttccatgact ccagctccat
    10021 ttgatacggc aatctttcca gcagattcaa acaagggaac aagagataca atcagaaaaa
    10081 tcaaaattcc ttgtacggca tagaccataa tgtttttgag gtagccaatc ccaacacttc
    10141 tccagtcatc actaaggaag gtcggaatgg taacaggggc aaaaggaatc attagataga
    10201 gttggataaa gcgaatggta atcaagatat tgacaaccat gatactaacc attcgcacca
    10261 accaaatgag aatcgcaaaa aagccaataa tcatttttcc tacaattcca gaacccttga
    10321 tgcctgagat agtatcgtaa ctagcaccac catttgtgac aagccctgcc acttgttcaa
    10381 taacataaga ggcaagggca ataatggctt ccacaataac cgtcgtattg gtaatcacga
    10441 ccgcgaccat aatgtagctg acaatcatag gtgctatggc ttcaaaggtc atcgcaccac
    10501 ctgagttggc gattttcttg gccatttttg agaattcgag tacgagaaca accgcaagaa
    10561 tagctactcc caagggctgc ataatcccct tggtaatggc tgtcatgtaa gaccacactg
    10621 tcggattaaa gtccgctagt gacttaacca agttggcagt tgtttctaaa tcaacttgaa
    10681 acccttcaaa aaggctatcg ctagatactt tttcagaggc tagaaataca aaaggtgacg
    10741 taaaattcat catcatgtca tgtgctgtcc tcctctatat ggtaatctgt gtcacaaaag
    10801 caccagcggc acctaccatg acaccaccaa caatttctaa aatggcattt cggacacctg
    10861 gtccaccatc tttaatgttg gttgacaggt tgataatgcc cataacaaca agaaaggccc
    10921 ctactgcaat taagcctttt tgtaatagag acatagcttg ggagaacatg gggctggcgt
    10981 ccactccgta aacaaagcct gttagttttt gattcatatt tttcctcatt tctattaata
    11041 tattgacatt tctgtgctta aatcccttat tgtatggcct gacaaatcta tctcttcctc
    11101 agtgattagg ggattgatgt ggtagtgcca ccagcgttca tcagattcct tatctgcaag
    11161 ccatttccaa ttcttatgtt tgagcggaaa atatttcttg gttcgaaaga caagcactcc
    11221 tgcaattcgt acgaggcatt catctcgttt catattccct acttcatctg ccgtcattaa
    11281 gtcacgggca attttctggt gagaggtgga acttgagccc gtctgaccaa atgaacgact
    11341 ggtacttctg acatcgatag tttgtttgcc tagaagtcca ctcatgaact taaaggtttc
    11401 ctcatcattc ccacccaaat ataagagact gtcgcagttc cctaatatgg ttttccaagc
    11461 ctctttttcc ttatacagtc cttggagttg ggcaatattt tgcaagattg gtactagact
    11521 catattccta gagcgaactg ttgaggtttg ttcagcaaag tctggaattt ctccgacatt
    11581 cgcaaactca tccagatagc ttcgaacatg aatcggcaat tgccctttaa agtccacatc
    11641 agcctgtctg gtcaaagtag agaaaaccgt agagaaaaat aaagcagata ggaaacgaaa
    11701 agtcgtatca ttgtctggaa ttacaagata gaccatggtc ttttgagtgc cccacgtttt
    11761 caaatccata gtgtctcttt gcgtcaaatc aatcactgat tggatattaa aaagggcaaa
    11821 tttagctgtt gtaaccgcaa tcaccgaatc caacgtctta tccttatagt tttggaaatc
    11881 cgcccaattt cgcatggtaa agttttcgtg gccatatttc ttagcatagt cttcaaacaa
    11941 gacttcaagg acacttttgt cctgattgtc tccctttgat aagagtttga tgagtttccc
    12001 aatctcagaa aaggctggat aacggccacg cttacgtctt gcttcctgct cttgcttgga
    12061 acttcctgga ggattgtaaa aatccaccaa ataagaggca atagctcgca ccaaggtcat
    12121 agaagcctca tcccaaaagg gatcactgcg agaaccattt cctttggtat tattaaaata
    12181 gaccgttaac atgcggttca aatcattttc agtttctaca tagcgaaagg gattaaaacc
    12241 atctgaattg gtcatattaa ccaagtctaa aaccttgact tgataaccgt tttctaaaaa
    12301 gagcttgcct gttttttcag ccaaatggtc cttaggatct accacaatat tggaacagtt
    12361 aagttggata aggttaggct tcacaaagcg aaaggtcttt cctgcaccag aacccccaat
    12421 gacaattaga tttttatttc ggtcaaactg gggtttcttc ttttccaaca aggttagacg
    12481 aacatcacga gtcaaaatcg tgtcattgaa aggattctta ctgtaaaaga atcgcttttc
    12541 cttactggtt ccaaagcgtg cagaaccgta ttcttcccct tctcgataga ccttctgtcc
    12601 tgtcgataca taaagataga ctagcgacat cgttataact ccaaggataa aggcaagaag
    12661 ggattttcga gtaaagctaa atagccataa aggattgaaa acctgattta acccctctcc
    12721 taagaggtag gcaaaacgtt ccataggtgg tgcattggtt aaactatcat agagtagggt
    12781 taggcggtga cagaaataac caaaggcaag tcccaagaat ccaaagacta atgcttttca
    12841 tctgaaatac attacaaggt aacctccttg gttctaacta ccgaaggttc tgtcactttt
    12901 attttctctt tggccaattc aatctcttgg tccaagcttt tatcaaaagt tagcccttct
    12961 aacttttctg gattagacat cagtttcttt aataattcat ctaagtgatg gtccagcaag
    13021 gtcttatctt tggcataaaa gtagagatag tctttttgcc aactaatagc aatcggtagt
    13081 ttttctgact ccatcaactc cttgaatttc tccacatcga ttggcttatc cagaatgtct
    13141 ttactgacat caatcgcttc aatggcgtaa gggctttgaa ggagttcttc cagtttttga
    13201 acaccaatct tataagctga atcttgggct aaggcttgcc tagccgacca ttctaagagc
    13261 tttaagaggg ttctaacagt aaataaacta cttctttcca cgtattgcat cgcttgacgt
    13321 tcttgttgtt cagatgacat gatgacttcc tcttctttga attccctatc aaacataagg
    13381 tgcttccata atacagaagc actcttgatt ttggtatcac aaaaaggtca agacataaac
    13441 caaactattc caaagtaaat gtaaggtcat tgccgtcata caatctgttt tcaaacgaac
    13501 aacagccaag gtcaccccaa gacagctata catgagccaa ctccctaact gatttgatcc
    13561 atgggctaaa gaaaagagaa aactggtcac tcctatttgt acaaaaggga atgtcaattt
    13621 ttcccacagc aattgcctat aaacaatctc ttcaaggaca cttgcattga ccagaaacaa
    13681 taaaaagata acatgtggaa cctgctttcc tacttcaact agtaccgatt gattcctagt
    13741 ctgaactgga aaaagaaaac taattaagac tgcaaaagaa accatacacg caaagccaag
    13801 aagcaaccat cttaggcgat tttgtaaggt aatatttttt gcttgaacag ttttgtgatg
    13861 agtaatctct agacaagcta cacctaaaag aagcgtttgt agcaggatta agaccttaat
    13921 cgtcatatag tcatgcaggt ataaactcac aagaagaccg ttaagctgta tggctagata
    13981 aaacaacact atccttatca ttgtcacctc ttgaataaat cttcataatc aatatctaag
    14041 actagaacga ttcgctcaac ccatcttgtc tgtggcatta aacgattgga tttgtaatgc
    14101 cgtaattttt gatagaggcg attaaactca cttggataaa catattgacc tttgaatact
    14161 ttgcgagcta gttctgccca agtgagttct ttttctgcca gaatgatttc taaattgtcc
    14221 caaaatcgtt cattcatctt cacacctacc ctgtcacttg tgtcatcagg ctggcctgaa
    14281 acagctcttc ttttacctgt ctgggaagaa aggttcgcac ttcatctaac ccaatagctg
    14341 gatagacatg attctggcag acaatgagag gcaaacgaag gttttggtct ggcttttgga
    14401 gaatgagctg gatcatctcg tttaaactga tggtgtattg acgcttaaag cgaagaaatc
    14461 gtggcgacag caactcaaaa caatccatgg ttttggcaaa gagtgacagt atgatttcac
    14521 ggtttacatc acatgctttt gtacaacggt aagtcacacc ataggtcgtc aaaatggtta
    14581 gtaagtctcg atttgtattg tcattatttc ctagatatac ctcaagcata ggctcctcct
    14641 tatagggtta ggctattttc aactgttggt tctggagttg agaaatagtg actcatatca
    14701 acgggcatcc gtccttcacc ggagcactta accgtcacca gagtcgttaa aataccatcc
    14761 tttcccctag cagtataatt ttgaccaaag gcacgaaagg ccaagtgatt gtctttcgtc
    14821 aatagtgtat ctactccatt tttaatatcc ctagtttcca aaaaatccga aatccgatga
    14881 agattggatt cgtagaatag gggatcattc atctctttgt ggtaatcatc ttcaaaagtc
    14941 acctcaaagt cacaatcaaa attggggagc gacaatatct tttggagtag ctgattgatt
    15001 tcaacttgat gaatacgttc ctctaattca gtacactcaa ggatactttt cttatgtagt
    15061 aggttcatgt ttttcttcct cttccattct tctaaattct cttgcaatgg cttcaataac
    15121 tgtgacagtc acactattac cagcctgttt gtatagttgg ctcttactag aaacactttc
    15181 tgctctttca taagcccaat caggaaaacc ttgaagtctg aaacactctc ttggtgtcag
    15241 tcgtctaatt ctcaggcgat agagttttcc gtctaagaca atccctgtga cttcatacca
    15301 cttatcctgt cgatattcca tagcagcaac tactactccc atattgtctg aagtcgtcag
    15361 agtattggat attcccttac ccactcgccc tctccgtttg gttgagtctg gatatgccag
    15421 attgacagag tctccaagag ttgcctttgc gtaccctctt tttgtggctt ccttgatttt
    15481 cagaaatggc aactcctctc tcagcaaaat ctttggcacc ttatctccac cctgcatggt
    15541 ggtcaaggtc ggtgacaaac cagctatgtc aaatactcta ccggtctggt caaagctagt
    15601 cggcagattt cctgcgacga caacaccatg tctatcttga ctagtcaaag taaacatagg
    15661 gtcttgatta tccttaaagc gacgcccatg ttggcgtttt tcaagtctat ctggtgttaa
    15721 gactggaatg gcgatttttg ccccctctcc tttacctctc gttagtgtag gagcaagtcc
    15781 agtcgtcaga tagacttcac cattcaaacc acgtttagag ggattgatat ttcctagcct
    15841 ttcaagatga gctgggctgt tttctcttct gagaggaaat aagaatctgg aacggtatct
    15901 tctagaatgt ccgataataa agacccgttc tctgttttgc gggacttgga agtccttact
    15961 gttaagcacc tgccattcga catcataccc caattcatcc agcgtggaga ggattgtggc
    16021 gaacgtccgt ccctcgtcgt gattgagtag gcctttgacg ttttccaaaa atagaaaacg
    16081 tggttggatt tgtttggcgc atctaacaat ttcaaaaaag agagtccctc gagtatcttc
    16141 aaatcccaat cgtcttcctg cgagtgaaaa agcttggcaa ggaaatcccc cgcagataac
    16201 atccacttgc cctctaaatt gtctaatgtc atggtctgtg acctctttaa tgtcatggta
    16261 ttctatttct tcttctgtct taaacatggc tttgtaggaa gttctagcga atttatcaat
    16321 ttcacaaaag cccaagcact catggccctg tgcttccatt cccagcctaa aaccgcctat
    16381 cccagcaaat aaatctaaaa atttcatttt tcctctcttt ccaaataaaa aagagcctta
    16441 cacttgtaaa actcttgcct atatatgatc atccatttct ggtgcacgga tgatttcaac
    16501 gatcaaaatg atgagcgaaa tcagatagat cccacctagt atccaccaaa tcatcttaat
    16561 cacctcacct tacttcttgt cgtctcagtt gcttggtcca ctctgacagc acaccattaa
    16621 acacgtattc agctatcact tccgctgacc gagcaaatct catatgttcc aatgcgtact
    16681 gataacgttc actaaaatag atcatggcat agtcactagc cgactgtgat agacctgtct
    16741 gtcttaactg gtcatgaacc aaatcccaga tatagtctcg atcgtacttt gtcacggcat
    16801 cgacttttga agaaaagttt tcttcttgtt tgtcatctac tagctgcctc tcctcctcgt
    16861 cctcaataag gaaatcactc ccttcagttt cactatattc agtctcattt ccttcagtct
    16921 cactaggggc tgaatttaag actggccccg tctttttttg agccccccct agtgtttttt
    16981 taacactagc cccgtctgaa tctaagactg ggatagattc atgttctaat tcccccaagt
    17041 aaattttatt tgccattcga cctttttcac tagaggactg ttggacttca tcaattaagc
    17101 catattcacg taaggttttc ttgatagaga gtaattttga ctttgaacag cctaaaagtg
    17161 ccatcagatt tgaattggaa taaatcaagt aaattgcccc atcttcatca atccaacctt
    17221 tactcaaaga caactccaaa cgatctttta aaaccgcgta ggctacctta acctccagtt
    17281 tcatatcctt ataccgttca ctctcaaaca aaattttagg gagtttataa taacgctctg
    17341 atgtctgata ttgatttgcg gttatacgtt tcatgattgt ccctccaaga ctaatattcc
    17401 aacatttcca aattcatcaa attggattaa tcctacttgt tccatttcat caatgagctg
    17461 agttgctttt acaatatcaa ctcccatgat agccatgagc tgacacatca cgagttgacg
    17521 tgatgattgt tcatactttt gcatcatttc ctcctgaaaa taaaaaaagc gagaacactt
    17581 ataaaaatgt tctcgctgaa ccaatatatt ttctgacgta tctatttttt gtctacgcag
    17641 tcgacatcca aacaaacgtt cacatcaatg tacttttttt gaaccttttt tatgtcaaaa
    17701 tcactctttt caataaagac aaaatgcttg aaaaagtgct taaaataaag gatttttaca
    17761 cgtttcttcg ttgtagcaat actacgcact ccacgtgtgt tgtccatagg ataggaacac
    17821 aaattattaa cctcgtcgct tgattgagga tacaatttac tgtcagcttt ctcattgact
    17881 tccttagcat tttttcttct gctcttaaat aatctcccgt cctgagaatc ttttttcccg
    17941 gtcttgtata tgatagtaat cattgcagga tcaatttcgc cttcatcgtt agttccacca
    18001 atgatgattt tatccactat actttcaaat acagctctat caaattcctc aagatattta
    18061 ttggattcaa gtaatttttt aaatccctca agccttttct tcaatgcttt ttcatcggta
    18121 agtgttacct ctaaagtcct cttttctgca agtagtttct ctttactaat agctatttca
    18181 ttatacttgt cctgatatat atccatgctg attgactcat tcagtcttaa ctcaacaaga
    18241 tccttttctt tctttagtat cctatcaagt tgatttgtta tcttcttcag gtctttagct
    18301 aaactgttgt ctttcaattc ttcttccaca gttttaagga attcattggt aatttccaca
    18361 ttattatggc atacctgacg atagctttcc ataaatgctt tttctattgc ttcttcttca
    18421 atccctttac tatgtggaca atacttcttt ccgtttttag tggcattgac acactgccat
    18481 ataacttttg tatattctga actcgaatgc caatttcttc ttgaaagatt atgaccgcaa
    18541 aatccacatt caagcatact gctaaaagca tattttcttg aatacttttc tcttttacca
    18601 ccattattgg caacagtatt tctgtttttt gaccttctta atctaatacc ttgagctttt
    18661 tcaaaatctt cttctgaaat gattggctcg tgatggtttt ctatataaaa cttatcctgt
    18721 tctccgaaat tatccaatct tctctttgaa ataggatcaa ccgtataggt ctttcccatc
    18781 ataagatccc ctttatattt ttcgtttttt atgattccta aaacagttgt ttcagtccat
    18841 cttttatttc ctcttggcga taaatatcct tgttcttcca gttctctgga aattaccata
    18901 ccgccaacac cttcaatgta tcttctaaaa atatatctta caatctcagc ttctttttca
    18961 ttgatagaaa tgcttttagt ttccggatca tagtcatagc ctaaacaccc ttgaaagccg
    19021 accatttctc ctctttccat cttcattctc aaaccttttt tgacattggc tgaaatgttc
    19081 tctacttcct gttgagcaac tgaacttaaa attgttaaaa gcaactcacc gtccattgtt
    19141 aaggtgttta tgttttcttc ttcaaaaaaa actgcaacat taaattcttt cagctttctt
    19201 acatacttta aggtatctaa tgtatttctc gcaaatcttg atatagactt tgtaattatc
    19261 atatctatat cgccattcat acagtcattt atcaaccttt gaaagtcaat tcttcgatca
    19321 acctgtgttc ctgttatcgc ttcgtcagca tatattccgg caagagtcca ctcgttattc
    19381 ttctgtataa attctgtgta gtgttctacc tgagaattat agctgttaat ctgatcttcg
    19441 gtatccgtac taactctgca ataagctgcc actctcttta ttgagcgttc aacacagcct
    19501 gatgcagttc ttttcagtgt ggtatcacct ttaataactt ttacttcttt cttcactgca
    19561 tccgcctcct tttttgtatc tttctatgca gtcttattat accacacttg caaaacatta
    19621 ttaatataat tctgttgaaa tgttgtactt tttcatcagt tttaacttta tcttcctgta
    19681 ttcaatatca tttagtaaat gtttggacag caagatagat agcatagata attggaggct
    19741 atattttagt aattcgttat tcattctaaa ccctcctcgt taaaaatcat ttttaagttt
    19801 tatgacattg gtaggtgctt ggcagcaaca taggaatctc acctccgccc cttattaaga
    19861 cgagccggct taaactattg aagtatcatt atcactactt gtatcaccga acagattgcc
    19921 acctctgttt tttatgtatt cttatttatc gctcgctttc ttatatcctt ggctaaccag
    19981 tattcataaa accgaaaact ttcagcagaa aggtcatggc gtaagtcata attctccaca
    20041 agtagataaa gtcctacctt ggtctattca gttgtcaaag atcaatattt gaaagggatt
    20101 gttttcttta cattttccta tttgccataa gcaggctatc tcttattcaa gaaagtaaag
    20161 gaggtcaaac tccccttcac tttacataag gaaaatttga cccctttggt taccgaattt
    20221 ctaaagttct tcgatgaatt ttttcagctt ttcaagaatt ttgtttcttc ttttgattaa
    20281 agccggatgt gtaatacttt tgagctttgc cactgagcga accgtttcat cattgaaata
    20341 caagcgttca ataatatctc tttcttcagc attaagcctt gatatagcat ttctaactgc
    20401 ttcaatcatc atctgtgttt caacaatctt ttctacatca acactttcat caacaatatt
    20461 atctacaaag tgtccgtcat gatccaatga tgaaaaaaag agcaagtggt tttttctgtc
    20521 cacctgctcc aaatactttt cgtgttctcg ttctcgccag tagactttgt atatctgctc
    20581 gctgacttta accctttgtc cgttgacata aaggtaatat tcttttggca tatatgtttc
    20641 ctccattctt tttttgtctg cttgttttca ggcaaaaaaa ggaggactcc tgcatcttgg
    20701 catgagaagt cctctaaaac gaaagaaact tgttctttta taaacactat ttaatttttc
    20761 aatataattt gtagattcat tatcttctat aaagcaaacc gaaaaaaggg aagaaaatgt
    20821 tcttactatt ttttattatt gaatataaag atttcttcat aatttcctcc ctcattctta
    20881 tatcgaa
//
LOCUS       DAVHSL010000039        20706 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000039 DAVHSL010000000
VERSION     DAVHSL010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20706
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.040"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            450..788
                     /locus_tag="VVR39_001472"
     CDS             450..788
                     /locus_tag="VVR39_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEU6030936.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            688..1158
                     /locus_tag="VVR39_001473"
     CDS             688..1158
                     /locus_tag="VVR39_001473"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030937.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            1317..2549
                     /locus_tag="VVR39_001474"
     CDS             1317..2549
                     /locus_tag="VVR39_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6030938.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLASIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(2667..3623)
                     /gene="cbpC"
                     /locus_tag="VVR39_001475"
     CDS             complement(2667..3623)
                     /gene="cbpC"
                     /locus_tag="VVR39_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU6030939.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLNTSN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYYVNYNGEWVR"
     gene            complement(3721..4410)
                     /locus_tag="VVR39_001476"
     CDS             complement(3721..4410)
                     /locus_tag="VVR39_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6030940.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(4422..5846)
                     /gene="gndA"
                     /locus_tag="VVR39_001477"
     CDS             complement(4422..5846)
                     /gene="gndA"
                     /locus_tag="VVR39_001477"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU6030941.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFAYIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(5922..7316)
                     /gene="mapZ"
                     /locus_tag="VVR39_001478"
     CDS             complement(5922..7316)
                     /gene="mapZ"
                     /locus_tag="VVR39_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU6030942.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(7328..8485)
                     /locus_tag="VVR39_001479"
     CDS             complement(7328..8485)
                     /locus_tag="VVR39_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU6030943.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(8570..8950)
                     /gene="rnpB"
                     /locus_tag="VVR39_001480"
     ncRNA           complement(8570..8950)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVR39_001480"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(8971..9300)
                     /gene="gpsB"
                     /locus_tag="VVR39_001481"
     CDS             complement(8971..9300)
                     /gene="gpsB"
                     /locus_tag="VVR39_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU6030944.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(9370..9897)
                     /locus_tag="VVR39_001482"
     CDS             complement(9370..9897)
                     /locus_tag="VVR39_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU6030945.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            9963..10559
                     /gene="recU"
                     /locus_tag="VVR39_001483"
     CDS             9963..10559
                     /gene="recU"
                     /locus_tag="VVR39_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU6030946.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10556..12715
                     /locus_tag="VVR39_001484"
     CDS             10556..12715
                     /locus_tag="VVR39_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEU6030947.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(12882..18185)
                     /locus_tag="VVR39_001485"
     CDS             complement(12882..18185)
                     /locus_tag="VVR39_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6030948.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVEEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVVAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLPTDKEKMYYFNTQTGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(18486..20468)
                     /locus_tag="VVR39_001486"
     CDS             complement(18486..20468)
                     /locus_tag="VVR39_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6030949.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT         5901 a         4645 c         3710 g         6450 t
ORIGIN      
        1 tcgatttgtc ctgttattat ttcattttac tataatattt gataagttat cctaaaagtg
       61 ttattatgtt gttgtgttat agattgattg aatctaacta aaggatccta ttcaattact
      121 agaactatca catactcaag gtcagctcac agatgagcaa ctattttggt tacaatgtct
      181 actaaattta agtcaaacaa ataatttagt caaaattaaa aaaaatagag gaacataaat
      241 atgattacaa aacagaatgt aatagtgttc tacgattttt actagataaa actgtaaatt
      301 ctgaaggaag gatcacttct tcaacagaat ttggaaattt cgtaagtaat ttatcattcc
      361 aacacggaat agctggacta ctgtttcctc taaataaatt gtacccccca gaactggatt
      421 ctaaaatact ctctatcatc aagaaggcag tgacaattag aacgacacac acatatgaat
      481 atcaatactc actgctattt ggtgatgcag gctatctatg gttactccta catttatttt
      541 ctatcagtaa aaatcaatac tatctacaat tagcaaacgt caccgctaag aaattaatag
      601 agaattatga tactctagag gaaatagact ttgcattggg aaaatctggt gtcctattat
      661 cattaataaa atactatcaa tttaccaatg acaatactct taaaactttc atccacaata
      721 gtatatgggg aaatttatca ttatttccta caaagagata cagccaaaga aagcatttta
      781 gactatagct ttgctcatgg atattgtgaa attgcatatg ctttatttgc ctattctaaa
      841 gtcttagaac cttctatgtt ctataatgat ctccatacat tccatgctga attaaaaaaa
      901 ttattagaaa aagttacttc taatactgaa aatttaggaa atttacaact ttcttggtgc
      961 gaaggaattt ccggaataat cttatatctt tgtatgtacg attgtgacgg aaacaaagat
     1021 attattagta aatatcaaga atttgttttt aaccatcatc taaaaatgat gacaggatat
     1081 tgccacggaa taactagctt actacaaacc actgtctaca atcaaaacaa attactgatg
     1141 aaaaaatcca acaggtaatt ttagcatgtt ctgaacgaga tgatcacgat ttactgatgt
     1201 ttcaaggaga tagtggtaaa acagatttgt ttgacttcgg aataggaagc agggggtata
     1261 ttggtgtcta ttaaataata aattcccatt cgatgtgcag acataaggag aaaagtatga
     1321 aattattttg gacaaacaac atatatagac agttgctgct aaacagctgt ttttcatcat
     1381 tcggcgacag tattttctac ctcgccatta tcaattatgt ggctcagtac aatttcgctc
     1441 cgctagcgat tttactgatt tccatttcag agatggttcc cctactatcg caactctttc
     1501 tcgggattct aggagatttt caagaaaata gagtcaaaca cgcactctgg attgccaaaa
     1561 tcaaaatcct gctctacgct attttgacag tatttctcgt cttgtcgccc ttttcattag
     1621 tttcagtcat tatgattgtc atcatcaacc tcatctctga caccttgagc tacctgtctg
     1681 cctacatgat gaacgccctc tacatcagtg taattaagga cgacctgcat gatgccatgg
     1741 ggttcaggca gtctctgatg agggttgtcc acattgtcgc caatctggct ggcgcattcc
     1801 ttatcaatgt tatgagtatt caaactattt cccttatcaa cactctgact tttgtcattg
     1861 cctttttggg tctgtatgtt attagacata ccttgtatga ggttgaaaaa aggattgaaa
     1921 tgtcacatac agcactgagt tttaagaaat attttcaaca tcttaaacag tcgctggctg
     1981 tgctcctgag gttaaaagat accgtcatac tactgtttct gacgaccagt atgattgcca
     2041 tcttggatgt gtcccctcgg ctgattgccc tccgcttcat ccaacagaca ctagcacaac
     2101 tgagcattgg gcaactcctc gccctgctct ccatcatcat gtcttgtgga gctatccttg
     2161 gcaatatgac cagcagtaat ctatttaaaa atatccgttt cacgcacctc ttggttttct
     2221 gtgagatttc cctattgact ctaataacta gtatcctttg tcaagcctat atcgtaattt
     2281 tcatgaccag tttcatcagt tctacgatta tcggcattct cagccctcgc ctacaagcag
     2341 ctgtctttgc ccatatcccc agtgacaaga tggggacggt gggctctgct ctgagcacag
     2401 tggacattct cgccccgtcc ctgctctccc tattagccct atccatagca tcgggcgttt
     2461 cggtgcagtt agcatcgata tttttgtatc ttattttaat tgctcttatc ttttgtcaat
     2521 ggttagtcaa gttcaacact cataactaac gaaaaagcat gtgtagattt cacatgcttt
     2581 taatctcccc aatagtcagg tcaagtacaa caaagtcact tctttgatta agcgagtgtt
     2641 ctaatataat tataagcgcc ctgtcattac cgaacccatt cgccattata gttgacgtag
     2701 tagccatcta cggtcgtatt cactgccaaa gcacctgagc tataagcata gtaccagttg
     2761 ccattgacct ggaaccaacc tgtcttcata tctccattac ttgtatttag gtagtaccaa
     2821 gttgaaccat cttgatacca gccagtcttc atatcaccat ttttattatc taagtaatac
     2881 catttgcctc gtacatattt ccaacctgtt gccatagaac cagaggagcc aaaataatac
     2941 cattttccgt ttactttttg ccaatctgta agcatcttac ctgaagcatc taggtagtac
     3001 catggagcag gtttgcttct atcaatgtca atagtaacat gaaaatcttg agtccaaccc
     3061 ttagcaactt caccaattgg tagtggattg taagaatcat cgccaaaatt tcctagctta
     3121 tttaaataat accaatgacc ctcttcataa atccagcctg tctttacagc ataattatta
     3181 tcaaaataat aagttctctt ttcagcagat agaggatatt gttcaccgta tacttttcct
     3241 gtattttcag acgtttttgc ctctagtact tgtttatctg tttgttctag caaagcacca
     3301 tcttgtccaa aatagtacca cttctcctga aggccaattt cgaagactgg acgattatca
     3361 aataaatcat cacgataacc tgttccagga atttctaagt attgccaacc gacaaccatc
     3421 tctccaatat caccaaaata gtaagtttta ccgtctattt tatgccaata gattgcttta
     3481 tgatcatctt ttacataata ttttctatta tccttatcaa caaatcggcc acctgtggta
     3541 ttcgcaaata ccgtatttgt agctagcaaa ccaaagaaaa agactgctag tagaacttgc
     3601 atcatttttt tcaaaagttt catttatata tcctcctaaa acgattgtag caaagacccg
     3661 actgcatgtc aatatataaa aactcctcaa aaaagcagtt acacaactgc aactgctttt
     3721 ctattcttgc atggtgtaac caacaccacg cacggtttta atgtagcttt tttgtccttt
     3781 aacatcaagc ttgctccgta gatagcggat atagacatct acgatatttg tctcggtcgc
     3841 actttcatac ttccaaacac tttccaacaa ttgctcacga gtcaatactt tcttgcttcc
     3901 cataagtgtc gccaaaaggt catactcacg gcgggtcaga gcaatcatct cttcaccacg
     3961 ataaaccgtg tgatgttcaa catctatcct aagattgcgg taggtccttg gaactttcat
     4021 cagactgcag tgttgatcaa tgaagtcccg acctcggaag atcgccgaaa tacgcgctac
     4081 cagattttcg ataaggactg gcttatagat gtatgaaact gcaaaacgct gaacaacttc
     4141 cagctcttct tgcaagtctt cccaatgatc taaaatcatg atgactgagg caggtttagt
     4201 tcggctcaat ttttctgcaa aatcctgagc catcatatct cccagattaa cgttcaataa
     4261 aatcaaatca tagtctgtct gaagagccat ggagagggct ttttgcccct cctctaccag
     4321 atcaacccga tactgctctt tctggagttc caaacttaaa aaatgagcta gatttcgttc
     4381 tttctcaagt aataaaatcc gtttccccat ggctgaccta cttatttttc gtcataccaa
     4441 gagtagtgga aggttccttc tttgtcttta cgttggtaag tgtgagcacc aaagtagtca
     4501 cgttgtgctt ggatcaagtt agctggaagg tcagctgaac ggtagctatc aaagtaagta
     4561 atagctgctg agaaagttgg cactggcaca ccagcttgaa ccgcaagagc tacgatatca
     4621 cgcactgctt gttgatactt agcagtaaca tccaagaagt actcgtccaa aagaaggttg
     4681 gcaagatctg catcgcggtt gtaagcatct gtaatctttt gcaaaaaacg agaacggatg
     4741 atacagccat cacgccagat agatgcgata tatgcaaatg gcaagttcca gttgttttct
     4801 ttagaggcta cacgcaattg agcaaatcct tgtgcgtatg aaatgatttt tgagaagtaa
     4861 agggcttgac ggatcttttc aatcaattca gccttgtctc cttcaaagtt gaaggcagct
     4921 ggttttggaa gcaccttgct agcatataca cgttcttctt tgtaagttga aatgtagcgt
     4981 gcaaacactg actcagtaat cagtgacaat ggtacaccaa ggtcaagaga tgattggcta
     5041 gtccatttac cagttccctt gttacctgca gcatcaagga tgtagtctac gattggtcca
     5101 tcttggcctt catcgtcttt acggctcaag atatcagctg tgatttcgat caagtagcta
     5161 tccaattcac ccttgttcca ctcagtaaag atttcagcca tatcctctgc agaaagacct
     5221 agcaagtgtt gcatcaagtc ataactttct gcgatcaatt gcatatcacc gtactcgata
     5281 ccgttgtgaa ccattttcac atagtgacca gctccatcag gaccgatata agtcacacat
     5341 ggtttgccat cttctggtgc tttagctgag atttcttcaa gaacatccgc aaccaattcg
     5401 taggcctctt tttgtccacc aggcatgata gaaggacctt caagagcacc tttttcacca
     5461 ccagaaactc cagtaccgat aaagttgata cctgagtttg ccaattcttc attacgacgg
     5521 atggtatctt tgtagaaagt atttccaccg tcaatcaaga tatcaccctt gtcaaggtgt
     5581 ggaagaaggg cttggatagt agcatctgta ccaggtccag cttgaaccat cagcatgata
     5641 cgacgaggtt tttcgattga gtttacaaaa ctttcaacgt catagcttgg tacaaaattc
     5701 ttttcaggat ggcaagcaat cacatcttcc gttttttctt tactacggtt gtagatagca
     5761 actgtgtaac cacgtgattc aatattaagg gcaaggttac gacccattac ggccatacct
     5821 acgacaccaa agttagcttt tgtcatttga cactcctctt gtttcatttg ttttatttta
     5881 tcatttttac ttttgaaaag aaagaatttt gtaacgactg cttagtagtc caagtcatcc
     5941 gcatgaccag cgccatttcc gacaaagtag cctgtcttac agttaagggt aaagagatag
     6001 gttccatctg gcttatagag gttgtaataa ccattgccgt taacgatatt gacacgttca
     6061 aggatatatt ggtctccagt gatatagcca cgtgaacgtg aagtcgctag aatttgttcc
     6121 aagacaccat ccgcaaaatc ccaggcagag ttattactat catcaatagc agactgatta
     6181 taggcaacac gactggcact tctttgaaca gcaacccctg cactcgagag acccatattg
     6241 acttcactgc gactacttct agtctcattt gaactacttg gttttggctc actagtcgta
     6301 tttgaacttg cttgacttga acttgagctg ctagtttgac ttaaacttga gctagaagta
     6361 cttgtttgct ggctcttacc aagactgata gccttatcta gcactttatc aagctccgta
     6421 tttccagttt taatatctgt aaatttagca tccgatttgg ctttggcatt ggtatccaac
     6481 acaccatcca caatagctga tttttcaaat tgtgcattga catcttgaat agccttgatt
     6541 tgcgttgcta gactatcata tttagatttg gcaagcgtat gttcacgact accttccagc
     6601 ttatcaagta aagtcttgag ttgattcagt ttatcaaact ggctattttt caaagccgtt
     6661 ttattgctat ctgtgtaaaa ggcgtcataa agtgtattaa aatcatccac atccgattga
     6721 ttggctgtag ttgattgaga agtttcaatt tccttggtcg aacgagccac ttgacggtag
     6781 acataataag cactgacaca aataattact gatacaagcg ccaaaacggt caaaataaag
     6841 ccttttttac ttttcttttc tgagtcctct tgatccagac gagaaaggtt ttgctcctct
     6901 tccacttctt cagtcatttc tgttggattt tcatcatcta gcaatagagg atccaagcct
     6961 tgctcctcat cgtccagagg caagggtagt aagatgtctt cagaagatgg aacttcctcc
     7021 gaagaagctt ctgacttctc tacagcctca cgcatctctt gaattaaatc atccagactc
     7081 tgagtttcaa cgaactcctc ttttttgtat tgacgagtcg caaacttatc cgcctcaatt
     7141 tcatctctgt gttgcttaac atacttgtcc aaaatggaat cctcaggcaa gactcctgct
     7201 tccacttctt catttttacg aatagcttga ccaactgtta gctcttttgc ttcatcaaaa
     7261 tcaaattgcg gttcttgacc ttcttttttt tgacgatttc gtcttttttt actcatgagt
     7321 atcctttcta ttttacctct tgccgtttga cacgctgacc aaaatattga tatagatcca
     7381 ctttcaaggt tccgttgtat aacttacgct tcttatctgc ttggctacca tacttgcttt
     7441 caaaagcttc atcactagtc aggataaatt tgctccaagt tttcagcggt gcaaatactt
     7501 gccccatctc agcatagagc ttggtcaccc ctgcatcatc tgacaaacgt tcaccataag
     7561 gcggattgga aatgattact ccattgattt tatcggaacg taaatcctgc acgcgcatct
     7621 gcttaaaagt aatgtctcct gcaacaccag ctacctgagc attggcctta gcaatttcca
     7681 ccatgcgagc atcaatatca cagcccatga tatccagctc aagctcacgg tctacttttt
     7741 tagccgcttc tgtgcgcact tcttgaatca agcgatcgct gatccagttc cattcctcaa
     7801 atgcaaaaga gcgacgaaga cctggcgcca tctttctagc aatcataact gcctcaatac
     7861 agaaagtccc cgaaccacag gtcggatcaa tcaaaggctt gtctggatac cagttagaaa
     7921 gttgtaaaat ggctgctgcc atattttcct tgataggagc gccacctttt tcggtacgat
     7981 aaccacgttt aaagaggcta gacccggtcg tatcaatcat gacagttgcc acatctttga
     8041 gaatagagac ctcaatctta aactctgggc cattctccat cagaggaacc ccttctgggc
     8101 gagcatagtg tttctgcaat ttcttgacaa cagctttctt agaaatagcc tgaacactgg
     8161 gctcattgtg aagtttggac ttaacacatt tagcttttga aatcgggaac cgagctccaa
     8221 gtggtaaata attttcccaa tccaaagcga aaactccctg aaatagctct tcaaaagtct
     8281 tagctgggaa cgttcctacg ataattttga tacgatctgc tgcccgaagc caaaggttgg
     8341 tttcgataat agctctcacg tctccttgaa aacgaacacg tccattttca acctgacaat
     8401 cgtagcccaa ctctcgcact tcacgaccaa cgacagcctc aagccctgct gccacagttg
     8461 caattaaatt aaattctttt ttcatgttac agtcttgcaa gacctttcta tatgtccact
     8521 ttaaaaaatg aggttgagaa aatttctcag ccccaaccta tatgcaattt tctataagcc
     8581 atgttttgtt ccagaagtga ctaggaccac ttccttcgat aatcatctgt ctaccactaa
     8641 cagctctagc tgatagcagt cagaatacta cgttcgtttc cgcgtactcc atgccccgac
     8701 caaaatttgg gttgctagct tgaggggttt accgcgttcc actctctctg tttccagaaa
     8761 gactccgtca ctgtggcact ttcaagccta ctctggccta tccaaggact tagccatttc
     8821 aactgccgta acgatttctc gtccctaggc ttatggtttc gcctagcaca aacactacag
     8881 gcatcacagc ctgtgctagc atggactttc ctcatgagaa gcaattctcc tcacgcgatt
     8941 atccaaaaat tgcacatctc aaataactac ttaaaaatct gagttatcta aaatttgttt
     9001 accaaaaact tctttttcca atctattcag gcgtttcaaa atatcaaaat tcgtcataga
     9061 acttgtaatt gccgcttcaa ggggttctgc ttgaactggt gaaggtttcg gtttacgagt
     9121 taattcttcc ttcaaatccg caatttcctg acgaagtgac ttgaccaagg cagcataggt
     9181 ttcatagtcc ttgatgacat cgtctaaaaa ctcgtcaact tctactttat tatagccacg
     9241 gacttcacgt ccaaactctt gttcaaaaat atctttcgct gaaaaaataa tacttgccat
     9301 gtctctctcc attctcgctt gctagtatta ttatataaaa aaaggcaaac aaaaatcaag
     9361 gtcaaagctt caattttcgg aaaaattttc agcaagttca tttaattgat caaatgttaa
     9421 tctctttata aaatagtcct cttgattttt catcttttgg taaaaataag ctagttttgt
     9481 ttcattttct tcatcataaa aaagatagga actagtcgtg ttttccagca aaaactgctg
     9541 gtaatctctt aactgcccct tgtgttcata gcgaggatag gcatatttga caaagtctac
     9601 ctgcttaaag cgactcagtt tcatctgatt gccttcattc caattttccc catgggtttc
     9661 aaaagcaaaa atggtggcca actggaaacc gtattcggtt ttcatctcct gagcaacctc
     9721 taaaacccaa tattcaaaac ccaaactccc tgtaaacaca agccaagaca ccccatctgc
     9781 tgccatagcc tctaaatctt tacgtatcgc ttttttaatc aatttaagac gaggatcctt
     9841 atcagaaaat aaacccaaat caaaagcaga atagcctaaa accaaagctg tagccatttt
     9901 taaccctttc tgtgcaaatt atggtataat aaagtgatgt tattgtacca ataaggagaa
     9961 ttatggtcaa ctatccacat aaagtttcat cacaaaaaag acaaacatct ctttctcaac
    10021 ccaaaaattt cgcaaatcga ggaatgtctt ttgaaaagat gatcaatgct accaacgact
    10081 actatttgtc tcagggcttg gctgttatac ataagaaacc aactcctatt caaatcgtac
    10141 aagtggacta tccacaacga agtcgtgcca agattgttga agcctatttt cgacaagctt
    10201 caacgacgga ctattctggc gtttataatg gatattacat cgactttgaa gtcaaggaaa
    10261 caaaacaaaa acgtgcgatt ccgatgaaaa attttcatcc acatcagatt cagcatatgg
    10321 aacaagtcct tgcccaacaa ggaatctgct ttgtccttct tcacttttct tctcagcaag
    10381 aaacctactt attgccggca ttcgatttga ttcgcttcta tcatcaagat aagggacaaa
    10441 aatcaatgcc acttgaatat attcgagaat atggatatga aatcaaggct ggtgccttcc
    10501 ctcaaattcc ttatctcaat gttatcaaag aacatttatt aggtggtaaa acaagatgaa
    10561 caaaccaacg attctgcgcc taatcaagta tctgagcatt agcttcttaa gcttggttat
    10621 cgcagccatt gtcttaggcg gaggagtttt tttctactac gttagcaagg ctcctagcct
    10681 atccgagagt aaactagttg caacaacttc tagtaaaatc tacgacaata aaaatcaact
    10741 cattgctgac ttgggttctg aacgccgcgt caatgcccaa gctaatgata ttcccacaga
    10801 tttggttaaa gcaatcgttt ctatcgaaga ccatcgcttc ttcgaccaca gggggattga
    10861 taccatccgt atcctgggag ctttcttgcg caatctgcaa agcaattccc tccaaggtgg
    10921 atcaactctc actcaacagt tgattaagtt gacttacttt tcaacttcga cttccgacca
    10981 gactatttct cgtaaggctc aggaagcttg gttagcgatt cagttagaac aaaaagcaac
    11041 caagcaagaa atcttgacct actatataaa taaggtctac atgtctaatg ggaactatgg
    11101 aatgcagaca gcagctcaaa actactatgg taaagacctc aataatttaa gtttacctca
    11161 gttagccttg ctggctggaa tgcctcaggc accaaaccaa tatgacccct attcacatcc
    11221 agaagcagcc caagaccgcc gaaacttggt cttatctgaa atgaaaaatc aaggctacat
    11281 ctctgctgaa cagtatgaga aagcagtcaa tacaccaatt actgatggac tacaaagtct
    11341 caaatcagca agtaattacc ctgcttacat ggataattac ctcaaggaag tcatcaatca
    11401 agttgaagaa gaaacaggct ataacctgct cacaactggg atggatgtct acacaaatgt
    11461 agaccaagaa gctcaaaaac atctgtggga tatttacaat acagacgaat acgttgccta
    11521 tccagacgat gaattgcaag tcgcttctac catcgttgat gtttctaacg gtaaagtcat
    11581 tgcccagcta ggagcacgcc atcagtcaag taatgtttcc ttcggaatta accaagcagt
    11641 agaaacaaac cgcgactggg gatcaactat gaaaccgatc acagactatg ctcctgcctt
    11701 ggagtacggt atctacgatt caactgctac tatcgttcac gatgagccct ataactaccc
    11761 tgggacaaat acccctgttt ataactggga taggggctac tttggcaaca tcaccttgca
    11821 atacgccctg caacaatcgc gaaacgtccc agccgtggaa actctaaaca aggtcggact
    11881 caaccgcgcc aagactttcc taaatggtct cggaatcgac tacccaagta ttcactactc
    11941 aaatgccatt tcaagtaaca caaccgaatc agacaaaaaa tatggagcaa gtagtgaaaa
    12001 gatggctgct gcttacgctg cctttgcaaa tggtggaact tactataaac caatgtatat
    12061 ccataaagtc gtctttagtg atgggagtga aaaagagttc tctaatgtcg gaactcgtgc
    12121 catgaaggaa acgacagcct atatgatgac cgacatgatg aaaacagtct tgacttatgg
    12181 aactggacga aatgcctatc ttgcttggct ccctcaggct ggtaaaacag gaacctctaa
    12241 ctatacagac gaggaaattg aaaaccacat caagacctct caatttgtag cacctgatga
    12301 actatttgct ggctatacgc gtaaatattc aatggctgta tggacaggct attctaaccg
    12361 tctgacacca cttgtaggca atggccttac ggtcgctgcc aaagtttacc gctctatgat
    12421 gacctatctg tctgaaggaa gcaatccaga ggattggaat ataccagagg ggctctacag
    12481 aaatggagaa ttcgtattta aaaatggtgc tcgttctacg tggaactcac ctgctccaca
    12541 acaaccccca tcaactgaaa gttcaagctc atcatcagat agttcaactt cacagtctag
    12601 ctcaaccact ccaagcacaa ataatagtac gactaccaat cctaacaata atacgcaaca
    12661 atcaaataca acccctgatc aacaaaatca gaatcctcaa ccagcacaac cataacattt
    12721 atcacccaga tttttctggg tgattttgtc atagcactat tgtatttatg tgcttaacaa
    12781 aagcctgaga agacatcttc tcaggctttt tctgtactat aaacctcatt ggaaaagata
    12841 gagactgctt ccgtaatctt gttaagaggt tttactaaat actagtcttt cttcgttttt
    12901 actacaaaga gagcagatag ggctaggcta acacctgcta ggaagagggc tgtgtcagat
    12961 tgactctcac ctgttgctgg caagatttgt tcaggtgttt ctggtctagc tatttcttgc
    13021 ttataatctg gcgtcttacc ttgctcggaa gctaaagagc taagtttaaa ctcaggtttc
    13081 tctacagttg gagcatctgg tttcgtagca gaatctttta attggttgag ataatctgca
    13141 aagtattcca ccattctttc cgtcaagaga tggttatccg tcgcatattt catgcttgcc
    13201 tgaacgctag ctacttcctc ttgattgtct ttgtctgtta atttctgagc cttagccaaa
    13261 gctgcttcat agcctgacaa gtcaagaggt gtttctgcta cctgtggacg agtaaagata
    13321 agttccgctg cagattggta tttatcgcca ccatctccgt aagtcttagt acctgtaagg
    13381 acaattttct tagccttaat tgtcttacca aaatcaatgt cttttggctt attgttatct
    13441 ggccaatcag ttgcagtaaa ggtatgctcc ttgccagact catctgtcac aacaagtttc
    13501 acatcacgca agttaccatt tgaacccgat ccacgtggaa cgtaacgaag tccagtgatt
    13561 tcagttggtt ctttcaagac catggttgca ggcttgccta catctccacc attccaagat
    13621 gtatgccata gactagacac attgccatca aaagcatttg caagaccttc ttgagcctga
    13681 gcaggagctg taagacttgc aaaatcatct gctaccaaag ccgttttctt ctgaaccaaa
    13741 gcattcttca aggcttcaat cttggcaatc tctgcacgcg cttcttccac actgatatca
    13801 tcatcggcct gactgaggtt aaagaccgcc tctttcaaag catccataga ctctttggtg
    13861 tagttagtca tggcaaccgt tggcaagtag ttcttcagag cattttctgt caacatctta
    13921 cctgttaggg taatttcttc gatttgaaga ttatccatca tgaagtcgtt ataaccacgg
    13981 aagttggcat ttccaccaga atcaccacga gtattacttg cattgccagt tgagtagata
    14041 cctacccaag tatcccctgt ttctgcacct gtcacaagga aggttgcctt cttggctttc
    14101 ttagaatctg tccaagtatt tggcaattca tgcatttcca agttgcttgc ttgagtgcca
    14161 cgacgacctg actggaattc tcccttaccg actacaaaag cataggtatt gtctgaacct
    14221 gcttcgtatt caaaggttac acggtaggtc ttacctgctt caaaacggaa gttttgcgga
    14281 atagtttggt aaaccaagtt acgacggctc actagtccat ttgtcttgag tgaccaattt
    14341 ccttcgataa catcatcgac tttcttacca ttccaaccac gttgtgtata tggatcgtgt
    14401 ttttcagaca agtgagtgcg gttatcttca acaccttcaa caccacccac tacaaatggg
    14461 aagataccct gagcaacatt ttcaaagtct tgcttgaagg tgcctttacc tgtatcatgc
    14521 ttgtctccgt acatgcttga attgttttca aaggtacgaa tttcatcaaa gtaagttgct
    14581 tgatcaccag cttcacgact caatgtcaga gtaacatttg agacgtccga tccagttgta
    14641 aagaaggcgt acatgttttg gaagtaactt gtatcgtcaa ctgtagcatt gtcacgacgt
    14701 gtattgtggg cgtaggcttt tacatagttg agggcgagag acttattggt ataagtagtc
    14761 acttcttttt caccagtatt cacagtgata cttgccttgg cattactacg gttatcgaca
    14821 ccgacataaa cggcatactt ggtatttggt ttcaagccag ttaatttctg agtgagacta
    14881 actttttctt tgtttccttg aatacgaagc atatcgtttg ccccttgaga cttgacaatt
    14941 tctgccttag aagcatcgcc tgaaatggtc caatgtttca aggtaccgct attaaatcct
    15001 tggtcataga tgtgcatgcc ttcactccat gacatttcag gattggtttg tttcgaacga
    15061 tagagaacgt atggttgatt tgctagaaga tctagggtaa ttttaccatc ttttacagtt
    15121 agttcctgct cttctgtctt accttggtca gttagcttgt aaaggtaaac cttgctcttt
    15181 gcccaatcgc ttggaagggt ccaagttgtt gcaccagtct gcgtattgaa gtagtacatc
    15241 ttttccttat cagtaggaag tttcttacca ttcgcatccc agttccaagg agtcaagtaa
    15301 gctgaaccat cttggatgac acgtccgttg agagttactg tacgttcgcg atattgtggg
    15361 ctattgacat catttgactt acgagttaca actactttat tattgtcagc atctaccaat
    15421 tccactcgca tttctggagt ccatttatag gtgctaccgt tatcggtcat agtcaccggt
    15481 gtaccatttt cccatttact tacagtgaag tgttggaagt acttagtcat gacgtcatgg
    15541 gcaaataagt tggttacata gccattgtag tcacttcttc cttgccagcc ttcaaagtct
    15601 ttcatgctgt agccacctag cagtggatag ttggctgcac caccataact tctgtagtcc
    15661 cctacccaag catctttttg gtggttacgg ataaagcggg tgatggcact gttgatacct
    15721 ttattggtgt agccaccgta ggtcaagtca gctgcccagt gatggaaggt agagtcgtac
    15781 tcaccaccat ggccccactc gatcgcaaag cgccagcctt gtttgttaat ttctttagca
    15841 agaacgtggg tagcccaggc accgttatca cctgattgac cattacccca aacgtccaca
    15901 tagataaagt cgagaccgtc accaagtttt ttcttcaaat cttcccaacg tgccaaacga
    15961 ccatgagcta ggtcataggc agcatcaatg ttgatacctt gatctagcca gttccaacca
    16021 tagctataac ttccatctgg attcttacgg agaatttttt cattgaagta tttagactca
    16081 ggataagttt ctgaagcgtt aacgtggata cctagatgag ctccatattt cttagccttc
    16141 tcaattaggg tcttgaagtc ttcgacacca ccgatacgct taccaatatc agcatagttc
    16201 aagtgaccag agtcgtgacc ttcactacca tatcctttaa ggagaacacc ttgcccaaga
    16261 ccatctgtgt ggagattgat tttcttgata ccatccaagg tcataaggaa tgggttttgt
    16321 gcttgagaac caaagttcat cgcgatacgg taagctgtga tatccttaac tttttcccaa
    16381 ccttgagggt tgttcataat gctacgataa gcaatggcac catcttgcca atcgactttc
    16441 ttgtctgcat tggcatcttc agtgataaca accttagcac ttggaagttc cttcgtgtat
    16501 tctgggaaaa caatgccctt ataagctttt tcccattgcc attcagagct gtggattcct
    16561 acatagttgg catttccgac tgtttcttta taagctgtca aacgagtcca gtcattcgaa
    16621 ccaccaccat agctattttg agagttactc caaacaccag cagcaagctt atctgtagaa
    16681 acaaatccat acatgtaacc cttagccaaa tccttcattg gattggttac atcgatatga
    16741 tcatctccgc tgacatgcgt attgtttgac atggttgccc catcaaactt agcaccagtt
    16801 tgatcactag aaacagagac taaagcattg ccgaggaaac taatagaaga aagtagtttt
    16861 ctttcgtcat caatcttttg acctggagtg acttgattgt ggttgacaat cttggtcaca
    16921 tcaaagtgca attgattgtc cacaacttgc aagcgtactg tcatttccgc attgattaag
    16981 tgagcatcat cgcgaatctt catcaagtac tctgctgttg tctcattgat tttcttataa
    17041 gtgacttcag gggtgattcg gtggttattg ataaagactt ggttgaactg ttgcacctgt
    17101 cctggcaaag tatgtccatt caaggtgtat tccttgacac gagggaaggc ttggtcaatt
    17161 actgccttaa gtaccttaga ctggatcgta tcataagtca ccttgctatc gtcaacaacc
    17221 ggacctgttt ctttctgggc aggagtatca tccgctttta cgccttcttg attgtctgtt
    17281 ttaacgctga caaccgtacg gtcattgcca taagagcccg ccttgagaag aatcttcttc
    17341 tcatttttaa gatggtcatt gaccgcagct ggtagagtca ctgtgtcaaa gagattgaca
    17401 tcgttattgc tggcatttag ctgaccgtct gacttgagag tgatagagag acggtttgtt
    17461 gatcctgttt caggagcaac aacacgacta cctctatacc aagtgctagt tgttggagat
    17521 ttatactccc agaaccagcc atccttgtca taaccgacaa aaacattatt attggtatct
    17581 ttaaatttca ggaagacacc aaagcgtgat ttgccctttt cagaatcatc tttgaaggtt
    17641 aaatcaacag ttgcatttcc attggcatca acggtcaagc ccttcttttc aaacagggct
    17701 ggtttacctg cgttatcatt ttgagcagtt gaggatagtt ggttgtagcg gacacctttt
    17761 tcttctcgga tagtgactgt tcccttttgt tcttttttct ctaccgtttg ccattcaggg
    17821 gttaccgtct taggtgtttc aggtttagca gctgcaggtt tatcctcttt tggtttttct
    17881 tcagccggtt tttctttttc aagtgctaat agttcttctt ctgtcttagg tccatctgta
    17941 acttctggag aaccttggtc ttcttccacc ttaggcgctt caaaatcacg cccatcattc
    18001 tcttttgctg ttgcaagagc agtagctaaa tcagctggta agttcgccgt ggaaccagac
    18061 tgcacgctat ctgcaagaac cggacttgtc ccaaagaatg cagctccaat cataacagaa
    18121 gcaacaccta atgaaaattt ccgaatacta tatttacaac gtttttcaaa taatccttta
    18181 ttcataaact tctaaatcct ttcatttttg ggcaaacgtt tacatttcct ttttaaaaaa
    18241 tactccttcc tctgaaagtg caatgcttaa ccctgataaa taaaaaataa ttatactttt
    18301 aatataacaa ataataactg ataaagcaat aggaaacaag taaaattaac aaaaattttc
    18361 tctattctga caaaaagagg ctccaacttt tgggggtcag tacatttaga atctttcttt
    18421 acaaatgtaa aaaaggattc agcattcaag agaaatacta aatcctttct tatattttgc
    18481 aacagttatt tcacatgttt tgcgagatct tcttgagcct ttttattaga ctcttctttt
    18541 tctttcatcc atttttcctg agctttttga tattcatcta cagtgactgc cttgtcttga
    18601 agttccaagt atttatacaa gactggttca cttgtacctt tatttcctga caatgcaaat
    18661 ggtattgtaa atggtaccat cttagacaag attggacgcc ctgtacgaga tgtagttgga
    18721 ataatcaaag cactatctgt caaccaagct tgggctgcag cgtatttatc atagcgttta
    18781 gcaacatctg tagtctcatc accagcctca gtaaccaatt tttcgtagtc atatagacct
    18841 acttttttag cagctacatt atcttcccct gagtcaaacc ctaaatatgt tttagtactt
    18901 tctcctacag atggtttgat gatatcaagg taggttgatg gatcggcaaa gtctggaccc
    18961 caaccgacat tatctgataa atcccagtct tcgccagcag cattttcagc aaaatatgta
    19021 atattgttta cttcgtcttt ttgtagttgt tgaatatcaa tgactacatt atccgctcct
    19081 aaagttgctt ccaaggattg tttcatagat tggacgcgct gaacttttgt agttgctgtt
    19141 tggtcaactg gcatatccaa atgaattggg aatgtcacac cttctgcttg taaggctgat
    19201 ttagctttag caaattcagc cttggctttt tctggattgt aaagaccatc ctgagaatct
    19261 gcaagattaa catccttcca ttcatcccca taagtaacca atttctcttt gaccatatcg
    19321 ccaaagtttt taccatctgc ttgaacaaat gttggtggaa caaagatatt acgtaagatt
    19381 ttgcttgctc cagtttgtcc attcaactga gaggcatagg ctgtacgatc aaaaccaaag
    19441 gcaatagcct gacggaaatc cttgtttaag agagcctttt tagtcgatgc cttttgttcg
    19501 tcgctggtct tagatgtgta tttataggac tgacggtcaa tatttgtacc aactagatac
    19561 gtaatagagt cttgttgagt atagacaata ttgtccttca tactcttctc aagctctgcg
    19621 aaacttgcac ttgttggata gagacgagct gctgtaaggc taccatcttt aaagttttct
    19681 gcaggtttgc tggtatcttg accatcccag aatgacaatt taactttgtc aatatgcaca
    19741 ttgtccttat cccagtagtt cggatttttc gcaaattcaa cagaagattt ggtcacaatg
    19801 gatttcaaca aataaggacc gttatacaag agactacttg gatccgtagc tttggcaaaa
    19861 tcatcccctt ttgaattcaa aaactcttca ttaactggcg caagcacacc catggttgtc
    19921 ttagaattcc agaagctttc tggtttgttc aaagtgtact gaactgtctg ttcatccaga
    19981 gccttaattc ctacttgtga gaaatctttg atttcccctt ttacataggc atccaaccct
    20041 ttgattgatt cttgaacaag gtaaagagca tctgattttt tatcagcagc atattttagt
    20101 cctgttacaa agtcttgagc tttgactgcc gcgtattctt caccttcaga agtataccat
    20161 tttgcatcct tacggatagt ataagtgtaa gtcaatccat ccttggatac agaccaatcc
    20221 tcagccatag acggcacaaa gttcccgtag cgatcatttt ctagcaaacc atcaaccacg
    20281 ttactggtaa tatttgctgt cgcagcctta gcagttgtca aatagttgag gttatcaggg
    20341 tctgtctcat aaatgtatga gaatgtcttc tcacctttag tgcttgaacc tgatccagag
    20401 catgcagcta aagtagtcgc cgccaataat gtcacgcccg caagggcaaa tagtcttgaa
    20461 cttttcatca ttttctcctt taaaactttc tctccattat agactctttt cagaaagttg
    20521 tcaacagaat tttcagaatt tttgaaaatt atttttcaaa caacatcttt gcaaaaaata
    20581 tccccaatta ttcaccccta atctaaaaac catccagaat ccttgcctta gcttagatcc
    20641 tggatggttt cttttttcac ccaatgggtg ttttttacta aacaaaaaag agtttcccct
    20701 ttatgg
//
LOCUS       DAVHSL010000040        20449 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000040 DAVHSL010000000
VERSION     DAVHSL010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.041"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            89..874
                     /locus_tag="VVR39_001487"
                     /pseudo
     CDS             89..874
                     /locus_tag="VVR39_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            923..1387
                     /locus_tag="VVR39_001488"
     CDS             923..1387
                     /locus_tag="VVR39_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU6030950.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPCLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            1544..1969
                     /gene="lacA"
                     /locus_tag="VVR39_001489"
     CDS             1544..1969
                     /gene="lacA"
                     /locus_tag="VVR39_001489"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU6030951.1"
                     /translation="MSIVIGADAAGLRLKEVVKNFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2000..2515
                     /gene="lacB"
                     /locus_tag="VVR39_001490"
     CDS             2000..2515
                     /gene="lacB"
                     /locus_tag="VVR39_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU6030952.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2526..3455
                     /locus_tag="VVR39_001491"
     CDS             2526..3455
                     /locus_tag="VVR39_001491"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU6030953.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPTGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            3457..4437
                     /gene="lacD"
                     /locus_tag="VVR39_001492"
     CDS             3457..4437
                     /gene="lacD"
                     /locus_tag="VVR39_001492"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU6030954.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4671..5507
                     /locus_tag="VVR39_001493"
     CDS             4671..5507
                     /locus_tag="VVR39_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6030955.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLITENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5543..5860
                     /locus_tag="VVR39_001494"
     CDS             5543..5860
                     /locus_tag="VVR39_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6030956.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEVGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5860..7551
                     /locus_tag="VVR39_001495"
     CDS             5860..7551
                     /locus_tag="VVR39_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6030957.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7766..9172
                     /gene="lacG"
                     /locus_tag="VVR39_001496"
     CDS             7766..9172
                     /gene="lacG"
                     /locus_tag="VVR39_001496"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6030958.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9262..9474
                     /locus_tag="VVR39_001497"
     CDS             9262..9474
                     /locus_tag="VVR39_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU6030959.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9753..10514)
                     /locus_tag="VVR39_001498"
     CDS             complement(9753..10514)
                     /locus_tag="VVR39_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6030960.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTDERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10696..11658)
                     /gene="nrdF"
                     /locus_tag="VVR39_001499"
     CDS             complement(10696..11658)
                     /gene="nrdF"
                     /locus_tag="VVR39_001499"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU6030961.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11846..14005)
                     /gene="nrdE"
                     /locus_tag="VVR39_001500"
     CDS             complement(11846..14005)
                     /gene="nrdE"
                     /locus_tag="VVR39_001500"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU6030962.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14086..14304)
                     /gene="nrdH"
                     /locus_tag="VVR39_001501"
     CDS             complement(14086..14304)
                     /gene="nrdH"
                     /locus_tag="VVR39_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU6030963.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            14655..14918
                     /locus_tag="VVR39_001502"
     CDS             14655..14918
                     /locus_tag="VVR39_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU6030964.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14924..16657
                     /gene="ptsP"
                     /locus_tag="VVR39_001503"
     CDS             14924..16657
                     /gene="ptsP"
                     /locus_tag="VVR39_001503"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU6030965.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16912..19365
                     /gene="phtA"
                     /locus_tag="VVR39_001504"
     CDS             16912..19365
                     /gene="phtA"
                     /locus_tag="VVR39_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU6030966.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRLQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNEDVDSLLKQLYALPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYH
                     FIPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQQTPEPSPGPQPAPNLKIDS
                     NSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKK
                     ENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDD
                     LLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAY
                     VTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRV
                     KGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDL
                     FATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEV
                     PQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEK
                     LLALLKGSNPSSVSKEKIN"
     gene            19523..>20449
                     /locus_tag="VVR39_001505"
     CDS             19523..>20449
                     /locus_tag="VVR39_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6030967.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGL"
BASE COUNT         6505 a         3743 c         4218 g         5983 t
ORIGIN      
        1 ccaatcttat tctgtatccc agcaatgagc gttccagtat ttgacaatat tagacttcct
       61 gcgaaacaaa atatggtata gtagttctat gaatgatgaa gcaagtaaac aactaaccaa
      121 tgcacaattt aagcgtcttg ttggtgttca gcgcacgact tttgaagaga tgttagctgt
      181 attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagtct
      241 agaagacctt cttatggcca ctcttcaata tgtgcgagaa taccgcactt atgaagaaat
      301 tgcggctgtt tttggtattc acgaaagcaa ctttatccgt cggagccaat gggttgaagt
      361 aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagctctg aggacacggt
      421 aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaaacaatta gcgaatcatt
      481 ctggtaaaaa gaaatgccac gctatgaagg ctcgagcgat tgtcacaagt caagggagaa
      541 ttgtttctat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata tcggacaagc
      601 tggtaaaatc ttggttgaca gtggttatca agggctcatg aagatatatc ctcaagtaca
      661 aactccacgt aaatccagca aactcaagtc gctaatagct gaagataaag cctataacca
      721 tgcgctatct aaggaaagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa
      781 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgag
      841 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ataaagaaac
      901 tagcaaggtc aggccttact ttattggtgg acatccagga tttaattgtc ctctacttga
      961 tgatgaagtc tatgaagatt attatctaga gtttgagaaa gaagagattt gctctgttcc
     1021 acgtcctttc ccagaaacag gtatgttgga tttccaagat agaagtccat gtctagaggg
     1081 acaaaaagaa atagatctta gttatgatct tttcagcaca gatgcagtga ctttggatga
     1141 attgcaatct cgaacaattg cccttcgttc tcttaaacat gataagggat tgaaagtgca
     1201 ttttgcagaa tttccaaacc tcatcatctg gtcaactttg aacaagggac ctttcattac
     1261 ctttgaacca tggtctggct tgtcaacatc ccttgaagaa ggagatcatt tagaagataa
     1321 gaagaatgtt tgtctcttag aagccaatca ggttgaagaa ttagggtttg agatagaagt
     1381 tttataaaaa agtaaaaaat aaataacaaa aacaaacaaa agctgttgac ttcttcaaac
     1441 aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagac agtcaataca
     1501 ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta ttgttatcgg
     1561 tgcagatgct gcaggtttga gattgaaaga agttgtgaaa aacttcttag aaaaagaaaa
     1621 cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga ctctcgctgt
     1681 tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg cttatggagc
     1741 tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag tatctgacga
     1801 acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta tgggtgcaca
     1861 acttgttggt gatgaattgg ctaaaaacat cgctaaagga tttgttaacg gtaaatacga
     1921 tggtggacgt catcaaatcc gggtcgacat gttgaacaaa atgggctaat tagattacag
     1981 taagaaaggt aagttaaaaa tgagaattgc aattggatgc gaccacatcg taacagatga
     2041 aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg actttggtac
     2101 atatgaccat acacggactc actacccaat ctttggtaaa aaagtagggg aagctgtaac
     2161 tagcggccaa gctgatcttg gggtatgtat ctgtggtact ggtgttggta tcaacaacgc
     2221 tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt gatatgacaa cagcccttta
     2281 tgctaaagaa caattgaacg ctaacgttat cggctttggt ggtaagatta ctggtgaatt
     2341 gcttatgtgt gatatcatcg aagctttcat tcatgctgaa tacaaaccat ctgaagaaaa
     2401 caagaaattg attgcgaaaa ttgaacacct tgaaagtcac aatgctcaac aaacagacgc
     2461 aaacttcttt acagaattcc ttgaaaaatg ggatcgcgga gaataccacg actaagaggt
     2521 gacctatgat tttaacagtc acaatgaacc catccattga tatttcctat cccttggatg
     2581 agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct ggtggtaagg
     2641 gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct actggtttag
     2701 tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta aagaaagatt
     2761 tcttctcaat tcagggagaa actcgtaact gtatcgctat tctccacgga gacaaccaaa
     2821 cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagac tttttggaac
     2881 atttcaaaaa actcttggag tcagttgaag tagtagccat ctcaggtagt ctgccaactg
     2941 gccttccagt tgattactat gcgagcttgg tagaacttgc taatcaagct ggcaagcctg
     3001 tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc cataaaccaa
     3061 cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa gtttctgagg
     3121 atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt gaatggatta
     3181 tcgtttcact tggtgccaac ggtacttttg ccaaacatgg tgacactttc tacaaggtag
     3241 atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact gtggcaggaa
     3301 tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcatcaag gcaaatgtcc
     3361 ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc aactatcaag
     3421 ctctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga acaaaaacgt
     3481 gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc atttgaccaa
     3541 cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac tgtggcccaa
     3601 atggaagaac ttaaagtctt ggtagcagat gaattgacta aatacgcttc atctatgctt
     3661 cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc tggtcttctc
     3721 cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc agactgcttg
     3781 gatgtctggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa attcttgctt
     3841 tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta catcgaacgc
     3901 atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaatcct tgcttacgat
     3961 gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag taaaaccaca caaagttatc
     4021 ggcgctatga aagtcttttc agacccacgc tttaacattg atgtcttgaa agttgaagtt
     4081 cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta tacacgtgaa
     4141 gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata catctacttg
     4201 agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca tgaatcaggt
     4261 gcaaacttta acggagttct ttgtggccgt gctacatggg caggatcagt tgaagcttac
     4321 atcaaagatg gtgaagcagc agctcgcgaa tggcttcgca caactggatt tgaaaacatt
     4381 gatgagctca ataaagttct tcaaacaaca gcgacttcat ggaaagaacg tgtgtaagaa
     4441 agtcctccta gtttaggaac atgaatctaa aaaaatttaa aaaaagttgt atgtaaaggt
     4501 ttacaaaata acttacttgt gctatactta aatcacaagt taatacaagg tgagtgttac
     4561 taagtaatat taggcatgat cacaggtgaa ttagaaatca gctgattttc tagttcattt
     4621 gtggtcattt tttgtactca tataccttta agatataaaa ggaggttgac atgtatcgaa
     4681 ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa tgataaggga gaagaggtga
     4741 ttgtaattgg taaggggatt gcattcggaa agaagaaggg ggatttgatt actgaaaatc
     4801 aggttgagaa aatctttcgg atgaagaccg aagagtccag agaaaacttt atggctcttc
     4861 tcaaagatgt tccgcttgat tttatcacag tgacctatga aatcattgat aagctatcaa
     4921 agaaatatca ttatccgatt caagagtatc tctatgtaac cttgacagat catatttact
     4981 gttcttatca agctctaact caaggaaggt acaaggatag taatctgcca gatatttccg
     5041 ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt tgaaatttac cgtcagaagc
     5101 tagcagatca ttttcctgag gacgaaatta ttcggattgc ttatcatttc attaatgctg
     5161 aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa gaggaaagaa attctcagga
     5221 atgttgaaga agttttaacg gactatgcaa ttcaacgaac taaaaagaat aaccatttct
     5281 atgatcgctt tatgatccat ttgaattatt tcttggatta tttagacaga tctagagatg
     5341 ataaccaatc acttctagat atggaagatc atattaaaca atcctatcca aaagccttcg
     5401 agattggttc caagatctat gatgtgatta cgcaacatac gggtcttgat ttgtataaaa
     5461 gtgaacgagt ttatctagtt ctacatatcc aacgtttatt gtcataaaaa tttatttaaa
     5521 actatataag gagaattcta tcatgaatag agaagaagta acattgttag gttttgaaat
     5581 cgtagcctat gctggcgatg ctcgttcaaa actattggaa gccttgaagg ctgctgaagt
     5641 tggtgatttt gaaaaagcgg acgctctggt agaggaagct ggtagctgta ttgcagaggc
     5701 tcaccacgcg caaacaagtc tattgactaa ggaagcttct ggtgaggact tagcgtatag
     5761 tgtgaccatg atgcatggcc aagaccactt gatgacaact atcttgttaa aggatttgat
     5821 gcaccatttg atcgaacttt acaagagagg agttaaataa tgaacaaact aattgcattt
     5881 atcgagaaag gaaagccttt ctttgagaaa ctatctcgta atatctatct tcgtgctatt
     5941 cgtgatggtt tcattgcagg tatgcctgtt attctcttct caagtatctt tatcttgatt
     6001 gcctttgtac caaactcatg gggctttaaa tggtctgatg aagttgtagc ctttctgatg
     6061 aaaccttata gctattctat gggtattctg gctctcttgg tagctggtac aacagctaag
     6121 tcattgaccg actcagtaaa ccgtagcatg gagaaaacca atcaaatcaa ctatatgtca
     6181 acgctgttag cagcgattgt tggtttgttg atgttggcag ctgatcctat cgaaaatggt
     6241 ctagctactg gattcttggg gacaaaaggt ttgctttcag ccttccttgc tgcctttgtt
     6301 actgtagcca tctataaggt ttgtgttaag aacaacgtca ctattcgtat gcctgacgaa
     6361 gttccaccaa atatctcaca agtctttaaa gatgtgattc cattcactct atctgttgtt
     6421 tctctttatg ctcttgactt attagcacgt cattttgttg gttctagtgt ggcagaatca
     6481 atcggtaaat tcttcgcacc actcttctca gcagcagacg gataccttgg tattaccatt
     6541 atctttggtg cctttgcctt cttctggttt gttgggattc atggtccatc tatcgttgaa
     6601 ccagctatcg cagctattac ctatgccaat gccgaagtca acttgaacct tctccaacaa
     6661 ggtatgcacg ctgacaagat tcttacttct ggtacacaaa tgtttatcgt taccatgggt
     6721 ggtactggtg cgacactggt tgttccattc atgttcatgt ggttaacaaa atcaaaacgt
     6781 aaccgtgcaa tcggacgtgc ttcagtagtt cctaccttct tcggtgtaaa tgagccaatc
     6841 ttgtttggtg cacctcttgt tttgaatcca atcttcttca ttccatttat ctttgctcca
     6901 attgcaaacg tatggatttt caaattcttt attgaaactc ttggaatgaa ctcattcact
     6961 gctaatctac catggacaac tccagctcca ctaggtctag ttcttggaac taacttccaa
     7021 gtgctatcat tcattcttgc tgcccttcta atcgtggttg acgttgtcat ttactatcca
     7081 ttccttaagg tctatgatga acaaattctt gaagaagaac gttcaggtaa gtctaatgat
     7141 gaattgaaag aaaaagttgc tgcaaacttc aacactgcaa aagcggatgc tattcttgaa
     7201 aaagcgggtg tcgatgcagc acaaaatacc atcactgaag aaacaaatgt cctcgttctc
     7261 tgtgctggtg gaggtacaag tggactcctt gcaaatgctt tgaataaggc agcagcagaa
     7321 tacaatgtcc ctgtgaaagc agcagcaggc ggctatggtg ctcaccgtga aatgttgcca
     7381 gagtttgatt tggttatcct tgctcctcaa gttgcttcaa actttgaaga tatgaaggca
     7441 gaaacagata agctcggtat taaacttgct aagacagaag gcgctcaata catcaaatta
     7501 actcgtgatg gaaaaggtgc cctagcattc gtacaagagc aattcgatta aggctaggaa
     7561 ctgtgaaaca gtctcccatc gttacggaaa tcgctatggc gaatttccta atcgccttat
     7621 taattcttcg gtaaaaagat atcgttttta cctcctcatg tcacaattca gtgacttggt
     7681 acaagaagtg agatggagaa gcatggctca ctgactcctc tcctctcact tttactttat
     7741 ttaaatcaag aaataggtga aaaaaatgac aaaaacactt ccaaaagact ttattttcgg
     7801 tggcgcaaca gctgcttatc aagcagaagg tgctacacat actgatggaa aaggaccagt
     7861 tgcttgggat aaatatcttg aggataacta ctggtacact gccgaaccag ctagtgattt
     7921 ttacaatcga tatccagttg acctcaagct agcagaagag tatggtgtca atggtattcg
     7981 aatttctatt gcttggtcac gtattttccc gactggttac ggccaagtaa atgctaaagg
     8041 tgttgagttt tatcataatt tatttgcaga gtgtcacaaa cgtcatgttg agccttttgt
     8101 aactcttcat cactttgaca cgccagaagc tctccactca aatggagact tcttaaaccg
     8161 tgaaaatatc gaacattttg tagactacgc tgccttctgt tttgaagaat ttccagaagt
     8221 aaactattgg acaaccttta atgaaattgg accaatcggt gatggtcaat atttggttgg
     8281 gaaattccct ccaggtatcc agtacgacct tgccaaagtc tttcaatcac accacaatat
     8341 gatggtgtct catgcacgcg cggtaaaatt gtacaaagag aaaggctata aaggagaaat
     8401 tggtgttgtt cacgccctgc ctactaaata tcctctagat cctgaaaatc cagcagatgt
     8461 tcgtgcagct gagttggaag atatcatcca caataaattc atcttagacg caacttatct
     8521 aggtcgctat tcagctgaaa ccatggaagg tgtcaaccat atcttatcag tcaatggtgg
     8581 tagtttggat cttcgtgaag aagattttac agcattagaa gctgcaaaag acttgaatga
     8641 tttcctagga atcaactact atatgagtga ctggatggaa gcctttgatg gagaaactga
     8701 aattatccat aatggtaaag gtgaaaaagg aagctctaag tatcaaatca aaggtgttgg
     8761 tcgtcgtgta gctcctgact atgtaccacg cacggattgg gattggatta tctaccctca
     8821 aggtttgtat gaccaaatca tgcgtgtgaa gaaagattat cctaactaca agaagattta
     8881 catcactgaa aatggtctcg gctataaaga tgagttcgtt gataacactg tttacgatga
     8941 tggtcgtatt gattacgtga aacaacactt ggagatcttg tctgatgcga ttgcagatgg
     9001 agctaatgta aaaggttact tcatttggtc attaatggat gtcttctcat ggtcaaacgg
     9061 ttatgagaaa cgttatggtc tcttctacgt agattttgaa actcaagaac gttatcctaa
     9121 gaaatcagct cactggtaca agaaagtagc ggaaactcag attatagact agtagaatta
     9181 gtcattagat atagaatttt agtgagtcaa aaagatgttc aaagatttta tccaatctat
     9241 ttatgaaaaa aagtttatat tataaatttc gaaaaatgct ctcaaatacc gtgtttgacg
     9301 agtgaagaat tgaaaagtct tggaaaatgg tatgtctcga ctggtaaaga atggatttgt
     9361 cattcagatg atgagctgga agaatttaaa aatctatttt taaattttat caatcctgaa
     9421 gaatgggata ctatctcctt tgattcagat tttatgccgt ttcaacaatc gtaaccaatt
     9481 tctcaaaaaa gttaaatctt atatttagta ctctgtaaaa ctcttatcta atcacgttgc
     9541 ttatactcaa tgaaaatcaa agagcaactt taaactagga agcgagtcgc agatttctca
     9601 atgcatagct ttgaggaatt gggcaaaaag tctttgatat agaaaaaagc atagtatcag
     9661 gtgttgaaac acctgatact atgcttttta ttgtgggaag atttactttt tttcttctga
     9721 aattgagttg ttacccaggc tctttcagtt tattaaggct tgatgacttt aatgtgttta
     9781 gatagcttaa aaaggattga atcacttagt ttagaatctg aaacaatagt atcaagattt
     9841 gatatattat aaaaagtata aaaatcaaac ttattgaact tactatgatc tgcgagtaaa
     9901 tattttttat tagaattatt taaagcgatg cgttgagcct ctccctcttc ctcgctaaaa
     9961 gtagctagag ctccgttttg aataccatta cagctaacga aagctttaga aaattggaga
    10021 ttagagagat tttgtagggt caatgtgcca acaaaagcac ctgtaatatc gcgataattt
    10081 ccacctatta aaatcaaatc tgttaatttt cgttcgctta aaatcagaaa aacaggtaga
    10141 ctgttggtta cgacgcggat attgtcaata ggcaactcac gcgcaaaaaa ctctaatgtt
    10201 gttcctggtc caatgaaaat agtttctctt tcttctacta gactgcctgc aaaatgggct
    10261 atttcttgtt tttctgccgt ttggagggct tgtttttcaa tatttgatcg ctcatcagtc
    10321 aaaagggagt tggttcgaag tttttcagct ccaccatgca cacgaatcag caaatcttta
    10381 tcagctaatt cctgtaaata gcgccttgca gtcatatctg aaacggctat ttcgtccata
    10441 atctgtttaa ccgttatggt tcctttgcta tttactatct ctaaaatttt ggttaatttt
    10501 tcttgtttga gcatattatc acctcgtttc ctactactat cttaccataa acaaactcat
    10561 cattcaaata caaaaacaac aaaatgaaac aaaaacaaaa atatcgaagt ttgttttcaa
    10621 aactttcgat atttttgttg ggttataact ttgatgtttc tagtttactt tttgatgatt
    10681 gagagtggtg gagaattagt ctaaaccgta gttatagtca tcgtcttgca tggcttcaac
    10741 ttcgccaaga aggtaaccat ttccgacttg agagaagaag tcgtggttgg aagttcctgt
    10801 tgaaataccg ttcataacga ttgggttgac atcttcagct gaatctggga aaagtggatc
    10861 ttgtcccatg ttcatgagag ctttattggc attgtagcga aggaaggttt taacctcttc
    10921 agtccaacca acaccgtcat aaagactctc tgtgtagcct tcttcatttt cataaagagt
    10981 atagagtagg tcgtacatcc attctttgag tttttcttgc tcttcttcag gcaattcatt
    11041 gaaaccaagt tggaatttgt aaccaatgta ggttccgtga acagactcgt cacgaataat
    11101 caatttaatg atttctgcaa cgttggcaag tttgttgtta ccgagatagt agaggggagt
    11161 gaagaaacca gagtagaaga ggaaggtttc gaggaagacg ctggcaactt tcttttcaag
    11221 tgggctgccg tttaggtaga tttcgttgac aatctcagcc ttcttttgta ggtaaggatt
    11281 ggtattggtc cattcgaaaa tttcttcaat ctcagcctta gtattcaagg tagaaaagat
    11341 tgatgagtaa gatttagcgt ggacagattc cataaattgg atgttattga aaacagcttc
    11401 ctcatgtggt gtacggatgt ctgcgcgaag ggcttgaacc ccagtttcag attgcatagt
    11461 gtcaagaagg gttaaaccac caaaaacttt tccgaccaag tctttctctt tgttagatag
    11521 ctttctccag tcatccaagt cgtttgataa gggaatacgt gtatcgagcc aaaattgctc
    11581 cgtcagtttt tcccaagttg atttgtcgat gacatcttcg atggcattcc agttaatggc
    11641 tttgtagtaa gtttccattt aaaatctctt tctgtgttta gtattgcgaa ctcacaatta
    11701 tttctacttt accataattc tataggagta tcgcacaaaa agtcggaagc ccgactttta
    11761 aaatgttaca taaattatgt tatgacatag tagatttgat tttatcagtg ctgcttaggg
    11821 aaaaatagtg tttctatgct agaaactaaa tcacacagct ttcacattgg ttggcgccga
    11881 cttctccacc gtcatctgta aaggtacgga cgtagtagat agacttgatt cccttgttaa
    11941 aggcatagtt acgaaggatg gacaagtcac gtgtcgtttg tttattttcc ctcttccatt
    12001 cgtaaaggcc ttttggaatg tcactacgca tgaagagggt gagtgaaagt ccttgatcca
    12061 cgtgttcagt cgcagcagcg taaacatcga tgactttacg catatccata tcgtaggcag
    12121 aagtgtagta aggaatggtt tctgtagaca agccagcagc agggtagtag attttaccaa
    12181 ttttcttttc ctgacgttct tcaatacgtt gcgtaatcgg gtggatagaa gcagaaacat
    12241 cgttgatgta gctgatagaa ccatttggcg ctacagcaag gcgattttgg tggtaaagac
    12301 catcttcttg aaccttgtcg cgaagttcag cccaatcagc aacaccaggg ataaaaacat
    12361 ttttgaagag ttctttaaca cggtctgatg ttggaacaaa ttcaccagtt acatacttgt
    12421 caaagtaact tccgttagca tagtctgatt tttcaaagtt gtggaaggta ataccacgtt
    12481 cacgcgcaat attgtttgac tctaccaagg tccagtagtt cataagcata aagtagatgc
    12541 ttgtaaattc aacagactca ggtgaaccat attcaatgag ttgttgggca aggtagctgt
    12601 gcagtcccat ggcaccgaga ccaaaggtgt gggcttggct atttccatgg tcaatcgttg
    12661 gtacagctac gatatgtgaa ctatctgtaa cgaaagtaag ggcacgaacc atagcacgga
    12721 tagaacgacc aaaatcaggt gaagtcatca tgttaaccac gttggttgaa cccaggttac
    12781 atgaaacatc tgttcccatt tgaaggaatt cttgagcatc gttgatcaag cttggttctt
    12841 gaacttgaag aatctcagaa cacaagttac tcatgataat ctttccatcg acaggatttg
    12901 cacggttagc cgtatcgatg ttgactacat aaggatagcc agactcttgt tgcaatttag
    12961 agatttcagt ttccaaatcc cgcgccttga tttttgtctt gcgaatattt ggatttgcga
    13021 ccaattcatc gtatttttca gtaatgtcga tgtaattgaa tggcacaccg tattcttttt
    13081 ctacagagta agggctgaag aggtacattt cttcattttt acgagccaat tcgtagaatt
    13141 tatcaggtac tacaacacca agtgatagag tcttgacacg tactttttca tcagcgtttt
    13201 ctttcttagt tgaaaggaaa gcgatgatat ctgggtgaaa gacgttgagg tagacaacac
    13261 cggcaccttg acgttgcccc aattggttgg agtaagagaa gctgtcttca aaaagcttca
    13321 taacaggaac gacacctgaa gcagctcctt catagccttt gataggtgca ccagcttcac
    13381 gaaggttgct gagggtaatt cccacaccac caccaatacg tgaaagttga agagctgagt
    13441 tgatagaacg tccgatagag ttcatatcat ccgtcacttg gattaggaaa caagatacca
    13501 actccccacg acgagcacgt ccagcattca agaaggaagg agtagcaggt tggtagcgtt
    13561 ggtggatgat ttcattggca atatcgattg caacagcttc attcccatca gcgaaataaa
    13621 gggcgttgaa gaagacacgg tcttccatat tttcaagata gtattcaccg tcattagtct
    13681 ttaaggcata ttgattgtaa aatttataag ctgccatgaa tgacttgaat tggaagtttt
    13741 ggtctttgat aaattgagcc aattcttcca agaactctgg acggtatttc ttgataaagg
    13801 ctgtttcgat gtagttgtgt tcaatgaggt aattgatttt gtctttgatt gaatcaaaaa
    13861 ccatagtgtt tggaactaca ttttctttaa agaaagcatc caaggcttcc ttatctttat
    13921 gaagcatgat ttgtccatta acaggacggt taatttcgtt attaagacgg aagtaagtca
    13981 cgtcttcaag atgttttaat cccataaaat ttcccttatc taattacaaa agaaaggctt
    14041 ctaagttagc cctaaaagca gtttcttctg gatgatgtac taagattatg ctaattgttt
    14101 cagttttcct ggttggaaac ctgaaaagac ttcagttggt gtttggataa caggagctgc
    14161 gctaaaaccg agctctttaa cttgatcgac gtactcaggt tgctcatcaa gattgatttc
    14221 acgataagag acattattac tgtccaagaa acgcttggtc attttacatt ggacacaatt
    14281 gtttttagaa taaacggtta ccattgtgta actcctcttc aaaatttaat actatcttag
    14341 tatatcagaa aataaaattt tgtcaatgat ttaaactaaa tatagtggtg ttcttttgtt
    14401 gtttttatat ataaacacaa tatatagtgt ttgtattgtg aaatagcaat gattatccta
    14461 taaattgttt ttgaagaaac tatatcctgt gttttgttat ctaggataga agattttcag
    14521 caagttatct gaaaggaaat tgaaggaaaa tccagaaaat gcttgaaaaa aatcctagaa
    14581 gatggtataa tactaaattg taagggttat cacatataac tcaaaaaaag aaagaacaaa
    14641 aggagagtca aactatggct tctaaagatt tccacgtagt ggcagaaaca ggtattcacg
    14701 cacgtccagc aacattgttg gtacaaactg ctagcaaatt tgcttcagat atcactcttg
    14761 agtacaaagg taaatcagtt aaccttaaat caattatggg tgttatgagt cttggtgttg
    14821 gtcaaggtgc tgacgtaact atctcagctg aaggtgcaga tgcagatgac gctatcgctg
    14881 caatctcaga aacaatggaa aaagaaggat tggcataagg gaaatgacag aaatgcttaa
    14941 aggaatcgca gcatctgacg gtgttgcagt tgcaaaagca tatctactcg ttcagccgga
    15001 tttgtcattt gagactatta cagtcgaaga tacaaacgca gaagaagctc gccttgatgc
    15061 cgctctacag gcatcacaag acgagctttc tgttattcgc gagaaagcag taggtacgct
    15121 cggtgaagaa gcagctcaag tttttgatgc tcacttaatg gttcttgctg acccagaaat
    15181 gatcagccaa atcaaggaaa ctatccgtgc gaagaaagtg aatgcagaag caggtctgaa
    15241 agaagttaca gatatgttta tcactatctt tgaaggcatg gaagacaacc catacatgca
    15301 agaacgcgca gcggatatcc gcgacgtgac aaaacgtgta ttggcaaacc ttcttggtaa
    15361 aaaattgcca aacccagctt ctatcaatga agaagtgatt gtgattgcgc atgacttgac
    15421 tccttcagat acagctcaat tggacaaaaa ctttgtaaaa gcttttgtaa ccaacatcgg
    15481 tggacgtaca agccactcag ctatcatggc acgtacactt gaaattgctg ctgtattagg
    15541 tacaaacaac atcactgaaa tcgttaaaga cggtgacatc cttgctgtta acgggatcac
    15601 tggagaagtg attatcaacc caacagatga acaagcggca gaatttaaag cagctggtga
    15661 agcctatgcg aaacaaaaag ctgaatgggc acttttgaaa gatgctcaaa cagtgactgc
    15721 tgacggtaaa cacttcgagt tggctgccaa tattggtact ccaaaagacg ttgaaggtgt
    15781 taacaacaac ggtgcagaag ctgttggact ttaccgtaca gagttcttgt acatggattc
    15841 tcaagacttc ccaactgaag atgagcagta tgaagcatac aaggctgttc ttgaaggaat
    15901 gaacggtaaa cctgttgtcg ttcgtacaat ggatatcggt ggagataagg aacttcctta
    15961 cttcgatatg cctcacgaaa tgaacccatt ccttggattc cgtgctcttc gtatctctat
    16021 ctctgagact ggagatgcta tgttccgcac acaaatccgt gctcttcttc gtgcgtctgt
    16081 tcacggtcaa ttgcgtatca tgttcccaat ggttgcgctc ttgaaagaat tccgtgcagc
    16141 gaaagcagtc tttgatgaag aaaaagcaaa ccttcttgct gaaggtgttg cagttgcgga
    16201 taacattcaa gttggtatca tgatcgagat tcctgcagcg gctatgcttg cagaccaatt
    16261 tgctaaagaa gttgacttct tctcaattgg tacaaatgac ttgatccaat atacaatggc
    16321 agcagaccgt atgaacgaac aagtttcata cctttaccaa ccatacaacc catcaatcct
    16381 acgcttgatt aacaatgtga tcaaagcagc tcacgctgaa ggtaaatggg ctggtatgtg
    16441 tggtgagatg gctggtgacc aacaagctgt tccacttctt gtcggaatgg gcttggatga
    16501 gttctctatg tcagcaacat ctgtacttcg tacacgcagc ttgatgaaga aactcgacac
    16561 agctaagatg gaagagtacg caaaccgtgc ccttacagaa tgctcaacaa tggaagaagt
    16621 tcttgaactt caaaaagaat acgttaattt tgattaatcg aaaagtccct gcaactcagt
    16681 tacagggact ttttttgata ttttaaaaag aattttcaag aaaatctttc ttataaaaag
    16741 tccaaccttg aaaaagtagt ggtcagaaca aaaaatactt aaatggttca taaaattctt
    16801 gacaagttgg agatttagga gtaaactatt aaccagttaa gtaatagaga ggagtttctg
    16861 caatttagaa atgaattgca actagaaata tcaaatagaa agagagtttc gatgaaaatt
    16921 aataagaaat accttgttgg ttctgcggca gctttgattt taagtgtttg ttcttacgag
    16981 ttgggactgt atcaagctag aacggttaag gaaaataatc gtgtttccta tatagatgga
    17041 aaacaagcga cgcaaaaaac ggagaatttg actcctgatg aggttagcaa gcgtgaagga
    17101 atcaatgctg agcaaatcgt catcaagata acagaccaag gctatgtcac ttcacatggc
    17161 gaccactatc attattacaa tggtaaggtt ccttatgatg cgattttcag tgaagaatta
    17221 ctcatgaaag atccaaacta taagctaaaa gatgaggata ttgttaatga ggtcaagggt
    17281 ggatatgtta tcaaggtaga tggaaaatac tatgtttacc ttaaggatgc tgcccacgcg
    17341 gataacgtcc gtacaaaaga ggaaatcaat cgacaaaaac aagagcatag tcaacatcgt
    17401 gaaggtggga ctccaagaaa cgatggtgct gttgccttgg cacgttcgca aggacgctat
    17461 actacagatg atggttatat ctttaatgct tctgatatca tagaggatac tggtgatgct
    17521 tatatcgttc ctcatggaga tcattaccat tacattccta agaatgagtt atcagctagc
    17581 gagttggctg ctgcagaagc cttcctatct ggtcggggaa atctgtcaaa ttcaagaacc
    17641 tatcgcctac aaaatagcga taacactcca agaacaaact gggtaccttc tgtaagcaat
    17701 ccaggaacta caaatactaa cacaagcaac aacagcaaca ctaacagtca agcaagtcaa
    17761 agtaatgagg atgttgatag ccttctgaaa caactttatg ccttgccact cagccaacga
    17821 cacgtagaat ctgatggcct tgtctttgat ccagcacaaa tcacaagtcg aacagctaga
    17881 ggtgttgcag tgccacacgg agatcattac cacttcatcc cttactctca aatgtctgaa
    17941 ttggaagaac gaatcgctcg tattattccc cttcgttatc gttcaaacca ttgggtaccg
    18001 gattcaaggc cggaacaacc aagtccacaa cagactccgg aacctagtcc aggcccgcaa
    18061 cctgcaccaa atcttaaaat agactcaaat tcttctttgg ttagtcagct ggtacgaaaa
    18121 gttggggaag gatatgtatt cgaagaaaag ggcatctctc gttatgtttt tgcgaaagat
    18181 ttaccatctg aaactgttaa aaatcttgaa agcaagttat caaaacaaga gagtgtttca
    18241 cacactttaa ctgctaaaaa agaaaatgtt gctcctcgtg accaagaatt ttatgataaa
    18301 gcatataatc tgttaactga ggctcataaa gccttgtttg aaaataaggg tcgtaattct
    18361 gatttccaag ccttagacaa attattagaa cgcttgaatg atgaatcgac taataaagaa
    18421 aaattggtag atgatttatt ggcattccta gcaccaatta cccatccaga gcgacttggc
    18481 aagccaaatt ctcaaattga gtatactgaa gacgaagttc gtattgctca attagctgat
    18541 aagtatacaa cgtcagatgg ttacattttt gatgaacatg atataatcag tgatgaagga
    18601 gatgcatatg taacgcctca tatgggccat agtcactgga ttggaaaaga cagcctttct
    18661 gataaggaaa aagttgcagc tcaagcctat actaaagaaa aaggtatcct acctccatct
    18721 ccagacgcag atgttaaagc aaatccaact ggagatagtg cagcagctat ttacaatcgt
    18781 gtgaaagggg aaaaacgaat tccactcgtt cgacttccat atatggttga gcatacagtt
    18841 gaggttaaaa acggtaattt gattattcct cataaggatc attaccataa tattaaattt
    18901 gcttggtttg atgatcacac atacaaagct ccaaatggct ataccttgga agatttgttt
    18961 gcgacgatta agtactacgt agaacaccct gacgaacgtc cacattctaa tgatggatgg
    19021 ggcaatgcca gtgagcatgt gttaggcaag aaagaccaca gtgaagatcc aaataagaac
    19081 ttcaaagcgg atgaagagcc agtagaggaa acacctgctg agccagaagt ccctcaagta
    19141 gagactgaaa aagtagaagc ccaactcaaa gaagcagaag ttttgcttgc gaaagtaacg
    19201 gattctagtc tgaaagccaa tgcaacagaa actctagctg gtttacgaaa taatttgact
    19261 cttcaaatta tggataacaa tagtatcatg gcagaagcag aaaaattact tgcgttgtta
    19321 aaaggaagta atccttcatc tgtaagtaag gaaaaaataa actaatgaaa aatgaaagtc
    19381 tcgataaaga ggctttcatt tttattatgt atatatgtaa aattcttgac aagcaatatt
    19441 aaaaagagta aactattaac tagttaatta accggtttat tactttatag tgaatcaaat
    19501 atacttaaga aaagaggaaa gaatgaaaat caataaaaaa tatctagctg ggtcagtagc
    19561 tacacttgtt ttaagtgtct gtgcttatga actaggtttg catcaagctc aaactgtaaa
    19621 agaaaataat cgtgtttcct atatagatgg aaaacaagcg acgcaaaaaa cggagaattt
    19681 gactcctgat gaggttagca agcgtgaagg aatcaacgcc gaacaaatcg tcatcaagat
    19741 tacggatcaa ggttatgtga cctctcatgg agaccattat cattactata atggcaaggt
    19801 cccttatgat gccatcatca gtgaagagct cctcatgaaa gatccgaatt atcagttgaa
    19861 ggattcagac attgtcaatg aaatcaaggg tggttatgtc attaaggtaa acggtaaata
    19921 ctatgtttac cttaaggatg cagctcatgc ggataatgtc cgtacaaaag aagaaatcaa
    19981 tcggcaaaaa caagaacata gtcagcatcg tgaaggaggg acttcagcaa acgatggtgc
    20041 ggtagccttg gcacgttcac agggacgcta caccacagat gatggttata tcttcaatgc
    20101 atctgatatc atcgaagata cgggcgatgc ctatatcgtt cctcatggag atcattacca
    20161 ttacattcct aagaatgagt tatcagctag cgagttggct gctgcagaag ccttcctatc
    20221 tggtcgggaa aatctgtcaa atttaagaac ctatcgccga caaaatagcg ataacactcc
    20281 aagaacaaac tgggtacctt ctgtaagcaa tccaggaact acaaatacta acacaagcaa
    20341 caacagcaac actaacagtc aagcaagtca aagtaatgac attgatagtc tcttgaaaca
    20401 gctctacaaa ctgcctttga gtcaacgaca tgtagaatct gatggcctt
//
LOCUS       DAVHSL010000041        20364 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000041 DAVHSL010000000
VERSION     DAVHSL010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.042"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(1..498)
                     /locus_tag="VVR39_001506"
                     /pseudo
     CDS             complement(1..498)
                     /locus_tag="VVR39_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            844..1797
                     /locus_tag="VVR39_001507"
     CDS             844..1797
                     /locus_tag="VVR39_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6030968.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLAKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANANQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1848..3038
                     /locus_tag="VVR39_001508"
     CDS             1848..3038
                     /locus_tag="VVR39_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU6030969.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISHVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            3187..3558
                     /gene="rnpA"
                     /locus_tag="VVR39_001509"
     CDS             3187..3558
                     /gene="rnpA"
                     /locus_tag="VVR39_001509"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU6030970.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKKHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3533..4357
                     /locus_tag="VVR39_001510"
     CDS             3533..4357
                     /locus_tag="VVR39_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6030971.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKSVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4376..5362
                     /locus_tag="VVR39_001511"
     CDS             4376..5362
                     /locus_tag="VVR39_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU6030972.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNVIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5413..6036
                     /locus_tag="VVR39_001512"
     CDS             5413..6036
                     /locus_tag="VVR39_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU6030973.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELVKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQANILDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            6167..7624
                     /locus_tag="VVR39_001513"
     CDS             6167..7624
                     /locus_tag="VVR39_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6030974.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7647..7928
                     /locus_tag="VVR39_001514"
     CDS             7647..7928
                     /locus_tag="VVR39_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6030975.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            8006..8491
                     /locus_tag="VVR39_001515"
     CDS             8006..8491
                     /locus_tag="VVR39_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6030976.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8508..9173
                     /locus_tag="VVR39_001516"
     CDS             8508..9173
                     /locus_tag="VVR39_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU6030977.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIRR
                     IWG"
     gene            9177..10040
                     /locus_tag="VVR39_001517"
     CDS             9177..10040
                     /locus_tag="VVR39_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU6030978.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKELDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            10042..10746
                     /locus_tag="VVR39_001518"
     CDS             10042..10746
                     /locus_tag="VVR39_001518"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU6030979.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10923..12596
                     /locus_tag="VVR39_001519"
                     /pseudo
     CDS             10923..12596
                     /locus_tag="VVR39_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
     gene            12708..13799
                     /gene="ulaG"
                     /locus_tag="VVR39_001520"
     CDS             12708..13799
                     /gene="ulaG"
                     /locus_tag="VVR39_001520"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU6030980.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13913..15895
                     /gene="tkt"
                     /locus_tag="VVR39_001521"
     CDS             13913..15895
                     /gene="tkt"
                     /locus_tag="VVR39_001521"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6030981.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVAAAKEL
                     ASKGEKVRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLKQS"
     gene            16006..16305
                     /gene="yajC"
                     /locus_tag="VVR39_001522"
     CDS             16006..16305
                     /gene="yajC"
                     /locus_tag="VVR39_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6030982.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16352..16780
                     /locus_tag="VVR39_001523"
     CDS             16352..16780
                     /locus_tag="VVR39_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU6030983.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16782..17192
                     /locus_tag="VVR39_001524"
     CDS             16782..17192
                     /locus_tag="VVR39_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6030984.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17492..20143
                     /gene="adhE"
                     /locus_tag="VVR39_001525"
                     /gene_synonym="adhC"
     CDS             17492..20143
                     /gene="adhE"
                     /locus_tag="VVR39_001525"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU6030985.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         6386 a         3676 c         4393 g         5909 t
ORIGIN      
        1 actcattttg aacaacttca tatcatgaca atagttcaca gcgatatcca aagaaacaat
       61 tctcccttga cttgtgacaa tcgcttgagg ttccatagaa tgacatttct attttaccag
      121 aataattggc tagttgattt ttttaggacg atttattttt acctctgttg catccacaat
      181 caccgtattc tcagcactaa gatgagttct tgaaatcgta acaccacttt gaacaagagt
      241 tacttcaacc cattggctcc gacggagtaa gttgctttcg tggataccaa aaacagccgc
      301 aatttcttca taagttcgat attctcgcac atattgaaga gtggccataa gaaggtcttc
      361 taggcttaat ttaggttttc gtccaccttt tgcgtgttta agttttaata cagctaacat
      421 ctctttaaaa gtcgtgcgct gaacaccaac aagacgctta aattgtgcat tggttagttg
      481 tttactttct tcataaattt tattgtatca tatttttgtt tcacaggaag tctaataaat
      541 aaaaattctt taaaattttg ttgggaaaat gggaaaagat ataaatggaa acttagtata
      601 acacttggaa aactctgtaa aaatagtaag tcaattcatg tcccgttttt tctctaggga
      661 agttgggcgg ctatatttat atgaccattt gtcgtaataa acatccctac caagggtcaa
      721 tagaaataaa ttcaacgaaa cttttgctgt cagatttaga tgcccaattt gtcatttata
      781 ctctttcata taggactttc tataaggatg gaaaaaagaa gggaaatttg ataagatagg
      841 aatatggatt ttgaaaaaat tgaacaagcc tatacctatt tactagagaa tgtccaagtc
      901 atccaaagtg atttggcgac caacttttat gacgccttgg tggagcaaaa cagcatctat
      961 ctggatggtg aaactgagct aaaccaggtc aaagacaaca atcaggccct taagcgttta
     1021 gcactacgca aagaagaatg gctcaagacc taccagtttc tcttgatgaa ggctggacaa
     1081 acagaaccct tgcaggccaa tcaccagttt acgccagatg ctattgcctt acttttggta
     1141 tttattgtgg aagagttgtt tacagaggag gaaatcacta tccttgaaat gggttctggg
     1201 atgggaattc taggcgctac tttcttaacc tcgcttgcta aaaaagtgga ttacttggga
     1261 atggaaatgg atgatttgct gattgatttg gcagctagta tggcagatgt aattggtttg
     1321 caggctggct ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga aagcgatgtg
     1381 gtcatcagtg acttgcctgt tggctattat cctgatgatg ccgttgcgtc gcgccatcaa
     1441 gttgcttcta gccaagaaca tacttacgcc catcacttgc tcatggaaca agggcttaag
     1501 tacctcaagt cagacggata cgctattttt ctagctccga gtgatttgtt gaccagtcct
     1561 caaagtgatt tgttaaaaga atggctgaaa gaagaggcga gtctggttgc tatgattagt
     1621 ctgcctgaaa atctctttgc taatgccaac caatctaaga ctatttttat cctacagaag
     1681 aaaaatgaaa tagcagtaga gccttttgtt tatccacttg ctagcttgca agatgcaagt
     1741 gttttaatga aatttaaaga aaattttcaa aaatggactc aaggtactga aatataaaat
     1801 agattttgtt ataatagttg aaaacgctta aaaaggggta tcatgttatg acaaaaacaa
     1861 ttgcaatcaa tgcaggaagt tcaagtttga aatggcaatt atacttaatg ccagaagaaa
     1921 aagtattggc gaaaggtttg attgaacgta tcggtttgaa agattcaatt tcaactgtaa
     1981 aatttgacgg ccgttctgaa caacaaattt tggatatcga aaatcataca caagctgtta
     2041 aaattttatt ggatgacttg attcgtttcg atattatcaa ggcttatgac gagattacag
     2101 gtgttggcca ccgtgttgta gcaggtggag aatatttcaa agaatcaaca gttgttgagg
     2161 gagatgtttt agaaaaagtt gaagagttga gtttgttggc tcctctacac aacccggcca
     2221 atgcagcagg tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt gtagttgttt
     2281 ttgatacttc cttccacaca agtatgccag agaaagctta tcgctaccct ctaccaacaa
     2341 aatattacac agaaaacaag gttcgtaaat acggtgctca tggtacaagt caccagtttg
     2401 tagcaggaga agctgcaaaa ctcttgggac gtccattaga agacttgaag ttaattacct
     2461 gtcatattgg taacggaggc tcaattacag ctgtgaaagc cggcaaatct gtagacactt
     2521 ctatggggtt cactcctctt ggtggtatta tgatgggaac gcgtacaggg gatattgatc
     2581 cagctatcat tccttattta atgcaatata cagaggattt taacacacca gaagatatca
     2641 gtcatgttct taaccgtgaa tcaggtcttt tgggagtttc tgctaattct agcgatatgc
     2701 gcgatataga agcagctgta gcagaaggga atcacgaggc tagcttggct tatgaaatgt
     2761 atgttgaccg tatccaaaaa tatatcggtc agtaccttgc agtgctaaat ggagcagatg
     2821 ccattgtttt cacagcaggt gtcggtgaaa atgcagagaa tttccgtcgt gatgtaatct
     2881 cagggatttc gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt ggcgttacag
     2941 gagacatctc aacagaggca gctaaaatcc gtgtcttggt tattccaaca gatgaagaat
     3001 tagtcattgc ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa aaatattcaa
     3061 tacaaggagt tgggaaagtt atttttccag cttctttttc tgatgaaatt gtccaaaacc
     3121 ttgctatgat tggctttttt gaaaaatatg gtataatagt agtaatttaa tagatggagt
     3181 tgagttttga agaaaaactt tcgtgtaaaa agagagaaag attttaaggc gattttcaag
     3241 gaggggacaa gttttgctaa tcgcaaattt gtggtctacc aattagaaaa ccagaaaaaa
     3301 cattttcgag taggtctatc agttagcaaa aaactgggga atgccgtcac tagaaatcaa
     3361 attaagcgac ggattcggca tattatccag aatgcaaaag ggagtctggt agaagatgtc
     3421 gactttgttg tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga gatggagaaa
     3481 aatctactcc atgtattaaa attatcaaag atttaccggg aaggaaatgg gagtgaaaaa
     3541 gaaactaaag ttgactagtt tgctaggact gtctctgtta atcatgacag cctgtgcgac
     3601 taatggggta actagcgata ttacagccga atcggctgat ttttggagta aatcggttta
     3661 cttctttgcg gaaatcattc gctttttatc gtttgatatt agtatcggag tggggattat
     3721 tctctttacg gtcttgattc gtacagtcct cttgccagtc tttcaggtgc aaatggtggc
     3781 ttctaggaaa atgcaggaag ctcagccacg cattaaggcg cttcgagaac aatatccagg
     3841 tcgagatatg gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat ttaaagaaat
     3901 gggtgtcaga cagtcagact ctctttggcc gattttgatt cagatgccgg ttattttggc
     3961 cctgttccaa gccctatcaa gagttgactt tttaaagaca ggtcatttct tatggattaa
     4021 ccttggtagt gtggatacaa cccttgttct tccgatttta gcagcagtat tcaccttttt
     4081 aagtacttgg ttgtccaaca aagctttgtc tgagcgaaat ggcgctacga ctgcgatgat
     4141 gtatgggatt ccagtcttga tttttatctt tgcagtttat gcgccaggtg gagtcgccct
     4201 atactggaca gtgtctaatg cttatcaagt cttgcaaacc tatttcttga ataatccatt
     4261 caagattatc gcagagcgcg aggccgtagt acaggcacaa aaagatttgg aaaatagaaa
     4321 aagaaaagcc aagaaaaagg ctcagaaaac gaaataaata aggaggaatc tggtaatggt
     4381 agtatttaca ggttcaactg ttgaagaagc aatccagaaa ggattgaaag aattagatat
     4441 tccaagaatg aaggctcata tcaaagtcat ttctagggag aaaaaaggct ttcttggtct
     4501 atttggtaaa aaaccagccc aagtggatat tgaagcgatt agtgaaacga ctgttgtcaa
     4561 agcaaatcaa caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga acgagcctgt
     4621 gaagacggtt agtgaagaaa ccgttgacct tggtcatgtg gttaatgtta ttaaaaaaat
     4681 agaggaagaa ggtcaaggta tttctgatga agtcaaggct gaaatcttaa aacatgaaag
     4741 acatgccagc actatcttag aagaaactgg tcacattgag attttaaatg aacttcaaat
     4801 cgaggaagcg atgagggaag aagcaggcgc tgatgacctt gaaactgagc aagatcaaac
     4861 tgaaaatcaa gacttgaaag agatgggctt gaaggtcgag caaagttatg atattgccca
     4921 ggtggctacg gatgtgactg cctatgttca agcgattgtg gatgacatgg atgttgaagc
     4981 tacactttca aatgattata accgtcgtag catcaatcta caaattgaca ccaacgaacc
     5041 aggtcgtatt atcggctacc atggtaaagt cttgaaggcc ttgcaactgt tggctcaaaa
     5101 ttatctttac aaccgctatt ccaaaacctt ctacgttaca atcaatgtca atgattatgt
     5161 tgaacaccgt gcagaagtct tgcagaccta tgcgcaaaaa ttggcgattc gtgttttaga
     5221 agaaggacgt agtcatcaaa cagatccaat gtcgaatagt gaacgcaaga ttatccaccg
     5281 tattatttca cgtatggatg gcgtgaccag ttactctgaa ggtgatgagc caaatcgcta
     5341 tgtcgttgta gatacagaat aagtaaaatc agggttgacc tgattttttg ctagctagag
     5401 gaggttaaac tgatgttgaa taagataaga gactatctag acttttctgg tttgcagtac
     5461 cgtagtcctg ataaagcggg agcagagcga gagaagatgc tggcgttccg ccacaaagga
     5521 caagaggccc gaaaggcttt tacagaactg gtcaaagcct ttcaagcaag ccatccagaa
     5581 tggcaactcc aacagactag tcagtggatg aatcaggccc agcgtttgag accacatttt
     5641 tgggtttatc tacagagaga cggacaagtg acagaaccta tgatggcctt acgtttgtat
     5701 gggacatcta ctgactttgg aatttctttg gaagtcagtt tcatcgaacg taagaaggat
     5761 gagcaaacac tgggcaagca ggccaatatt ttagacattc caaccgttaa agggatttat
     5821 tatctaacct actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga aaagcgtcgt
     5881 actttacgcg agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa ggtagatgtt
     5941 cctatgacag aaaattcgtc tgaagaagaa atcgtagaag gcttattgaa gtcttattct
     6001 aaaattcttc cctattatct agctacgaga aaataagata atttgtaaaa catcataaat
     6061 catacagtcc aagagtgaac agtccgctgt gtaattcttg gtctttttgt ttgcgctttc
     6121 gcattatata ataaacttac aaaaacaatt caaaaggaga acaattatgg aagtcgtttc
     6181 aagtgttcta aattggtttt ctagcaatat tttgcagaat cccgcatttt tcgtaggttt
     6241 attggtgttg ataggatatg cacttttgaa aaaacctgcc catgacgttt tttcagggtt
     6301 tgttaaagca acagtagggt atatgttgct taacgtgggt gctggtggtt tggttacaac
     6361 ctttcgtcca atcttagcag ctcttaacta caaattccaa attggtgcag cggttatcga
     6421 cccttacttt ggacttgctg cagcaaacaa caaaattgca gcagagtttc cagattttgt
     6481 tggaactgca actacagctc tattgattgg tttcggaata aatatcttgc tcgtagctct
     6541 tcgaaagatt acgaaggtaa gaaccctctt tattactggt cacatcatgg tacaacaagc
     6601 tgcaacagta tctcttatgg ttctattctt agtaccacaa ttgcgcaatg cttacggtac
     6661 agcagcgatt ggtatcatct gtggacttta ctgggcagtt agttcaaata tgactgttga
     6721 ggcaactcaa cgcttgactg gtggtggcgg atttgcgatt ggtcaccaac agcaatttgc
     6781 aatctggttt gtagataaag tagcaggacg ctttggtaag aaagaagaaa gtttagacaa
     6841 tcttaaatta cctaagttcc tctcaatctt ccacgataca gttgttgcat ctgctacctt
     6901 gatgctcgta ttcttcgggg ccattctttt aatcttgggt ccagacatta tgtctaataa
     6961 agaagtcatc acttcaggaa ctctattcaa tcctgctaaa caagatttct ttatgtacat
     7021 tatccaaaca gcctttacct tctcagttta cttgttcgtt ttgatgcaag gtgtccgaat
     7081 gttcgtatct gagttaacaa acgctttcca aggtatttca aacaaattgt tgccaggttc
     7141 attcccagcg gttgacgttg cagcttctta tggatttggt tctccaaatg ctgtcttgtc
     7201 aggatttacc tttggtttga ttggtcaatt gattacaatt gtcttgctca tcgtctttaa
     7261 aaatccgatt cttattatta caggatttgt accagtgttc tttgacaatg cagccattgc
     7321 ggtctacgct gataaacgcg gcggatggaa agcggctgtt atcctttcct ttatatcagg
     7381 tgtccttcaa gttgctctag gagctctttg tgtggccctt ctcgatttgg catcttatgg
     7441 tggctaccat ggaaatatcg actttgaatt cccatggctt ggatttggat atatcttcaa
     7501 ataccttggt attgttggtt atgtacttgt gtgtctcttc ttgcttgtta ttcctcaact
     7561 tcaatttgcc aaagcaaaag ataaagagaa atattacaac ggtgaagttc aagaagaagc
     7621 ttagtatcta gaaaaggaga aataaaatgg ttaaagtatt agcagcgtgc ggaaatggaa
     7681 tgggttcatc aatggttatc aagatgaagg ttgaaaatgc tctccgtaag cttaatcaaa
     7741 cagattttac agtcaattca tgcagtgtcg gtgaagctaa aggtttagca gtaggatatg
     7801 acatcgtaat cgcttctctt catttgattc aagaattgga agggcgaact aatgggaagt
     7861 taattgggct tgataacttg atggatgata aagaaatcac cgaaaaactc agtcaagcac
     7921 tacagtaaaa ggttggaggg gggctggaca gaaactgaga gttatcgttt ctgtccttct
     7981 ccctctttaa ataaaggagg cagatatgaa tttaaaacaa gctttaattg acaacgactc
     8041 gatccgacta ggtttagagg ctaacgattg gaaagaagca gtcaaggtag cagtagatcc
     8101 cttgattgaa agtggggcaa ttttgccaga gtattacgat gctatcattg aatcgactga
     8161 agagtatggg ccttactata tcttgatgcc aggtatggct atgccccacg ctagacctga
     8221 agcaggtgtg caaagtgatg ccttttcatt gattacctta caaaatcctg ttgtattttc
     8281 agatgggaaa gaggtatctg ttttgttggc actagcagca acaagttcaa aaattcacac
     8341 aagtgtagcc attccacaaa ttattgccct atttgaatta gaagattcta ttgcacgttt
     8401 acaggcttgc cagactaaag aagatgtctt ggctatgatt gaagaatcta aggatagccc
     8461 ttatctcgaa ggattggatt tggaaagtta gaaagaggaa taaagaaatg acaaaaagaa
     8521 tacctaattt acaagttgca ttagaccatt cagacttgca aggagcgatt aaagcagctg
     8581 tttctgttgg tcaggaagta gatattatcg aagctggaac tgtttgcttg cttcaagttg
     8641 gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga taagattatt gtggcagaca
     8701 caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt ggagcagact
     8761 ggatgacttg tatctgttgt gcaaccatcc ctactatgga agcagctcta aaggctatca
     8821 agactgaacg aggagaacga ggcgaaatcc agatcgagct ttatggcgat tggacttttg
     8881 aacaagctca gctttggcta gatgcaggta tctcacaagc tatttatcac caatctcgtg
     8941 atgctcttct tgctggtgaa acttggggtg aaaaagacct taataaggtt aaaaaactca
     9001 ttgacatggg cttccgtgta tctgtaacag gtggtctaga tgtagatact ctcaaactct
     9061 ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg aattacagag gctgcggatc
     9121 cagcaggagc agcgcgtgcc ttcaaggatg aaatcagacg aatttggggg taaatcatgg
     9181 tacgtccaat tggaatttat gaaaaggcaa ccccaacaca ctttacttgg ctagaacgtt
     9241 taaattttgc caaggagtta ggctttgatt ttgtcgagat gtctattgac gaacgtgacg
     9301 agcgtttagc aagacttgac tggagtaagg aagaacgctt ggaagttgtc aaagcaatct
     9361 atgaaactgg tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc tacccattgg
     9421 gttcaaaaga tccagttcta gaggaaaaat ctctagaact catgaaaaaa tgtatcgaat
     9481 tagctcaaga cttgggagtt cgtacgattc aattagctgg ttacgatgtt tactatgagg
     9541 aaaagtcacc ccagacacgc caacgtttta tcaaaaattt gagaaaagcc tgtgactggg
     9601 ctgaagaagc tcaggtggta cttgctattg aaattatgga tgatcctttc atcaatagca
     9661 tcgaaaaata tttggctata gaaaaagagc ttgactctcc cttcctcttt gtatatccag
     9721 atattggtaa tgtgtctgca tggcataatg atatctatag tgagttttat cttggtcatc
     9781 atgccatcgc agctctccat ctcaaggata cttatgcagt gacagaaagt tcaaagggcc
     9841 agttccgaga tgtacctttt gggcaaggtt gtgtcaaatg ggaagaagct ttcgatattt
     9901 taaaggaaac caattataat ggacctttcc taatcgaaat gtggtctgaa aattgtgaaa
     9961 cagtagaaga aacacgcgca gccattcaag aggcgcaagc tttcctctat ccactcatta
    10021 agaaagcagg tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa acgagtctgt
    10081 gatgccaatc aatcattgcc aaaacatgga cttgtcaaat ttacctgggg caatgtatcg
    10141 gaagtcaatc gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga ttatgacgaa
    10201 ttgacacctg aaaacatggt agtgactgat ctagatggta agatcctaga aggggattta
    10261 agaccatctt ccgacctccc aactcatgtg caattatata aggcttggtc agaaattggt
    10321 agtgtggttc acacccattc gacagaagct gttggttggg ctcaggcagg tcgtgatatt
    10381 cctttctacg gaacaaccca tgcagattat ttctacggtt caatcccttg cgcccgtagt
    10441 ttgaccaagg atgaagtaga agtggcctat gaaaaagata ctggcctggt tatcgtagaa
    10501 gagtttgaac atcgcggact taacccggtt gaagtaccag gaattgttgt acgcaatcac
    10561 ggtccattca cctggggcaa aaatccagag aatgctgttt atcactctgt cgtactagag
    10621 gaagtatcaa agatgaatcg ctttacagaa caaatcaatc caagagttga acctgctccc
    10681 cagtacatac tagaaaaaca ctaccaacgt aaacatggac caaatgctta ttatggtcaa
    10741 aagtaagaac gacgaaggag gagaaaaaga taaatttagc tcctcttttt acatttgatt
    10801 tttattgaga gtaaagttgg agttgaagta attttgaaag attttttaga aatagcgctt
    10861 gatatatatg gtaaaataaa aagaattgct gtgatatcaa tagatttggg ggatttttta
    10921 atatggtact ggataaggca agttgtgatt tgcttcaata tttgatggat caagaaacgt
    10981 ccaaaacgat tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa atttattatc
    11041 acattgacaa aatcaatgct gctctgggtg acgaggcgct tcacatcatt agtattccac
    11101 gaattggtat tcacttaacg gaagagcaga gagatgcttg ttgtaaacta ttatcggaag
    11161 tagattcgta cgattatatc atgagtgcgc atgaacgtat gatgataatg ttactatgga
    11221 taggtatttc taaagaacgt attacgattg aaaaattgat agagttaaca gaggtatcta
    11281 ggaatactgt tctcaatgat ttgaatagta ttcgttatca actaactttg gaacaatatc
    11341 aggtgacctt gcaagtgagc aagtcacagg gatagcacct tcatgcccac cctcttaata
    11401 aaattcagta tcttcaatcg cttctatatc atatttttat ggaagaaaat gccacttttg
    11461 tatctatttt agaagataag atgaaagaga ggttagatga tgagtgtttg ctttctgttg
    11521 aaatgaacca attttttaag gaacaggttc ctttagttga acaagattta gggaagaaaa
    11581 taaaccatca tgaaataact tttatgttgc aggttctacc ttatttgctg ttaagctgtc
    11641 ataatgttga acagtatcaa gaaagacatc aggatataga gaaagaattt tctttgataa
    11701 gaaaaagaat agagtatcag gtgtctaaga aattaggaga acggttgttt caaaagtttg
    11761 aaatttcttt gtcaggactt gaagtttctc ttgtagctgt tctcctcctc tcctatcgta
    11821 aagatttgga tattcatgca gaaagtgatg attttcggca attaaaactt gctttagaag
    11881 aatttatctg gtattttgaa tcacaaatcc gaatggagat tgagaacaag gatgatttgt
    11941 tacgaaattt gatgatccac tgtaaagcct tgttatttag aaagacttac ggtatttttt
    12001 ctaaaaatcc tctaacaaaa caaattcgat ccaagtatgg agaattattt ttagtcacta
    12061 gaaaatctgc ggaaatttta gaaggagcat ggtttattcg gctaacagac gatgatattg
    12121 cctatttgac gattcatatt ggaggatttt taaaatatac accatcgtct caaaaaaata
    12181 tgaaaaaagt ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt ttgctgaaac
    12241 aatgcaaact ttattttcca aatgagcaaa ttgacactgt atttacaaca gaacaattta
    12301 agagtgtgga agatattgca caagttgatg tagtgattac tactaatgat gatttggata
    12361 gcagatttcc gattttaagg gttaatccta tccttgaagc agaagatatt ttgaaaatgc
    12421 tagactatct taaacacaat atatttcgta ataagagcaa aagtttcagt gaaaatcttt
    12481 ctagtcttat ttcgtcttat attgtagaca gcaagttggc tagtaagttc caagaagagg
    12541 ttcaaacact tataaatcaa gaaatagtag ttcaagcttt tttggaagat atttgaagga
    12601 cagtccaatg atgaacacaa acctgtgttt ttcttggtct tttttagtgt tttgaagggt
    12661 ggtatactaa tctcaaagat aacaattata tccaaaggag gcaacatatg ccaaacgtca
    12721 aagaaattac aagagagtca tggattttag ccactttccc agagtgggga acatggttga
    12781 acgaagaaat cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg tggctaggca
    12841 actgtggtac ttggattaag acaccagctg gtgctaacgt tgtcatggac ctttggtcaa
    12901 accgtggaaa atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa atggcaaata
    12961 tggcaggtgt tcgtaagttg caaccaaact tgcgtgttca gccaatggtt atcgatccat
    13021 ttgctatcaa cgaactagac tattacttag tttcacactt ccacagtgat catatcgacc
    13081 catacacagc tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag tttatcggtc
    13141 cttaccactg tggacgaatc tgggaaggat ggggggttcc aaaagaacgt atcatcgttg
    13201 ttaaaccagg tgacactatc gaattaaaag atatgaagat tcatgcagta gaatcatttg
    13261 accgtacttg cttggtaact ctcccagtga acggtgctga tgagacaggc ggtgaacttg
    13321 ctggcttggc tgttacagat gaagaaatgg ctcaaaaggc tgttaactat atctttgaaa
    13381 caccaggtgg aaccatctat catggtgcag attctcactt ctcaaactat tttgcaaaac
    13441 atggtaaaga ctttaaaatt gatgttgctt tgaataacta tggtgaaaat ccggtaggta
    13501 tccaagacaa aatgacatct atcgaccttc ttcgtatggc agaaaatctg cgtaccaaag
    13561 tcattatccc agttcactat gatatctggt ctaacttcat ggcttctact aatgagattc
    13621 tagaactttg gaaaatgcga aaagatcgct tgcaatacga tttccatcca tttatctggg
    13681 aagttggcgg taagtacact tatcctcaag atcaacactt agtagaatac catcatccac
    13741 gtggttttga tgattgtttt gaacaagact ctaacattca atttaaagct ttgctataat
    13801 ataaaaatat tctttggagg ttatccgtat gttgcatgat acggataatt ttcatataat
    13861 agtaaaatag aatgtgtgat tcaataatca cctcaaatag aaaggaaatt ctatgtcaaa
    13921 tctatctgtt aatgcaattc gttttctagg tattgacgcc attaataaag ccaactcagg
    13981 tcatccaggt gtggttatgg gagcggctcc gatggcttac agcctcttta caaaacaact
    14041 tcatatcaat ccagctcaac caaactggat taaccgcgac cgctttattc tttcagcagg
    14101 tcatggttca atgctccttt atgctcttct tcacctttct ggttttgaag atgtcagcat
    14161 ggatgagatt aagagtttcc gtcaatgggg ttcaaaaaca ccaggtcacc cagaatttgg
    14221 tcatacggca gggattgatg ctacgacagg tcctctaggg caagggattt caactgctac
    14281 tggttttgcc caagcagaac gtttcttggc agccaaatat aaccgtgaag gctacaatat
    14341 ctttgaccac tatacttacg ttatctgtgg agacggagac ttgatggaag gtgtctcaag
    14401 cgaggcagct tcatacgcag gtttgcaaaa acttgataag ttggttgttc tttatgattc
    14461 aaatgatatc aacttggatg gtgagacaaa ggattccttt acagaaagtg ttcgtgaccg
    14521 ttacaatgcc tacggttggc atactgcctt ggttgaaaat ggaacagact tggaagccat
    14581 ccatgctgct atcgaaacag caaaagcttc aggcaagcca tctttgattg aagtgaagac
    14641 ggttattgga tacggttctc caaacaaaca aggaactaat gctgtacacg gcgcccctct
    14701 tggagcagat gaaactgcat caactcgcca agccctcggt tgggactacg aaccatttga
    14761 aattccagaa caagtatatg ctgatttcaa agaacatgtt gcagaccgtg gcgcatcagc
    14821 ttatcaagct tggactaaat tagttgcaga ttataaagaa gctcatccag aactggctgc
    14881 agaagtagaa gccatcatcg acggacgtga tccagtcgaa gtgactccag cagacttccc
    14941 agctttagaa aatggttttt ctcaagcaac tcgtaattca agtcaagatg ccttgaatgt
    15001 tgtggcagct aaattaccaa ccttcctagg tggatcagct gaccttgctc actcaaacat
    15061 gacttatatc aagacggatg gacttcaaga cgataccaat cgcttgaatc gtaacattca
    15121 gtttggtgtt cgtgaatttg caatgggaac aatcttgaac gggatggccc ttcatggtgg
    15181 acttcgtgta tacggtggaa ctttcttcgt cttctctgac tatgtgaagg cagctgtccg
    15241 cttgtcagcc ttacaaggac ttcctgtgac ttatgtcttt acccatgatt caatcgcagt
    15301 tggggaagat ggtccgactc acgaaccagt tgagcattta gcaggtcttc gtgctatgcc
    15361 aaatctaaat gttttccgtc cagcagatgc gcgtgaaacg caagcagctt ggtaccttgc
    15421 agtgacaagt gagaaaacac caactgccct tgtcttgaca cgtcaaaact tgactgttga
    15481 agatggaaca gacttcgaca aggttgctaa aggtgcttat gttgtatatg aaaatgcagc
    15541 cgactttgat accatcttga ttgcgacagg ttcagaggtc aatctagctg tcgcagctgc
    15601 caaagaatta gctagtaaag gcgaaaaagt ccgcgtagtt agcatgccat ctacagatgt
    15661 ctttgataaa caagatgcag cttacaagga agagattctt ccaaatgcag tccgccgtcg
    15721 tgttgcagtc gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc tcgatggtgc
    15781 cgttctaggt attgatacct tcggagcctc tgccccagca ccaaaagtat tggcagaata
    15841 tggctttact gtagaaaatc ttgtaaaagt tgttcgaaac ttgaaacaat cctaaaaatc
    15901 agggcgtaag ctctggtttt tcttaccaga aaagtaaggt acaatcttgt aaaagtagct
    15961 gaaatttgat atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa tccaaatatt
    16021 acttttttaa tcatgcttgt aggtatgatg gccttgatgt tctttatgca acgctctcaa
    16081 aagaaacaag cacaaaaacg tatggaaagc ttaaataaac tacaaaaagg ctatgaagtg
    16141 attacaatcg gtggacttta tggaacagtc gatgaagtag atacggagaa gggaacaata
    16201 gttcttgacg tagatggagt ttacttgact tttgaactag ctgctatcaa gacagtatta
    16261 ccgctgaaag aaacagcttc actagaaggc gcaattgaaa aataagaagg gatcacgaac
    16321 tcccgttttt ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg tctgtctggg
    16381 aaatatttgc cgtagcccta tggccgagtt tgttatgaaa tcaatgacag ataactacga
    16441 aatccaaagt cgagcaactt cctcttggga acatggcaat ccgattcata aggggactca
    16501 gggaattttt caagagtatg agattcctta tgacaagaac aagacatcgc ttcagattag
    16561 taaggaagat tttgaagcct ttgattatat tatcggaatg gacgcttcaa atgtttccga
    16621 cttacgtcag atgtgtccag tagactgtca agataagatt tactcatttt catctgaaag
    16681 tgttccagac ccttggtata caggagattt tgaagaaacc tatcgacgtg ttcaagaggg
    16741 ctgtcaagct tggttagaac gtttagaaaa ggagagttaa ggtggaaaat cttacgaatt
    16801 tttacgaaaa gtatcgtgtc tatctgactc gtccacgttt agagcttttg gcagtagtta
    16861 ccattgtttt ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa ggtgtcttaa
    16921 aactcgataa tggaacgatt gtttatgatg gcagtcttgt ccgtggtaaa atgaatggcc
    16981 aaggtaccat taccttccaa aatggagacc aatatacagg tggcttcaac aatggagcct
    17041 tcaacggaaa aggtaccttt caatctaaag aaggctggac ctacgaaggt gattttgtaa
    17101 atggtcaggc tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt tatgaaggaa
    17161 cttttaaaca aggcgttttt caacaaaaat aaagcctcct tatcaaagga ggtattatta
    17221 gaattacaag gtaagcgctt acctgtaaat ccctttcttt ccaaatccct cttccaagca
    17281 agtttgtgaa ataaaaaata tttgaaataa atttcacaaa cttcaaagat aaaacctgat
    17341 aagaaaagaa aatgagaaaa gtttcacaag agtttaaaaa ttctttgtga aatgtttatg
    17401 aaactgttta caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa ttaacaaagg
    17461 atatcgttcc ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg tgacaccaga
    17521 ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag ctctagttgc
    17581 ccttgaagaa atgcgtaaat tggatcaaga gcaagttgac tacatcgttg ccaaagcatc
    17641 agtagcagct ttggatgccc acggagaatt ggctttacat gcctttgaag aaacaggacg
    17701 tggtgtattt gaagataaag caactaagaa cttgtttgcc tgtgaacacg tagtaaacaa
    17761 catgcgccac actaagacag ttggcgttat cgaagaagac gatgtaacag gattgactct
    17821 tattgctgaa ccagttggtg ttgtttgtgg tattactcca acaacaaacc caacatcaac
    17881 agcaatcttc aaatcattga tttcattgaa gacacgtaac ccaatcgtct ttgccttcca
    17941 tccatcagca caagaatcat ctgctcatgc agctcgtatc gtccgcgatg cagctatcgc
    18001 agctggtgct cctgaaaact gtgtgcaatg gattactcaa ccatctatgg aagcaacaag
    18061 tgcccttatg aaccacgaag gtgttgcgac aatccttgca acaggtggta atgccatggt
    18121 taaggcagct tattcatgtg gtaaaccagc tcttggggta ggtgccggaa acgttccagc
    18181 ttatgttgaa aaatcagcaa acattcgtca agcagcacac gatatcgtca tgtctaaatc
    18241 atttgataac ggtatggtct gtgcatctga acaagcagtt atcattgata aagaaattta
    18301 cgatgaattt gtagcagagt tcaaatctta ccacacttac tttgtaaaca aaaaagaaaa
    18361 ggctcttctt gaagagttct gcttcggcgt caaagcaaac agcaaaaact gtgctggtgc
    18421 aaaattgaac gctgacatcg ttggtaaacc agcaacttgg attgcagaac aagcaggatt
    18481 tacagttcca gaaggaacaa acattcttgc tgcagaatgt aaagaagttg gcgaaaatga
    18541 gccattgact cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg aaagccgtga
    18601 agatggtatt actaaggctc gtcaaatggt tgaatttaac ggtcttggac actcagcagc
    18661 tatccacaca gctgacgaag aattgactaa agaatttggt aaagctgtta aagctattcg
    18721 tgttatctgt aactcacctt ctacttttgg tggtatcggg gacgtttaca atgccttctt
    18781 gccatcattg acacttggat gtggttctta cggacgcaac tcagttgggg ataacgttag
    18841 tgccattaac ctcttgaata tcaaaaaagt cggaagacgg agaaataaca tgcaatggat
    18901 gaaacttcct tcaaaaacat actttgaacg tgattcaatt caataccttc aaaaatgtcg
    18961 tgacgttgaa cgtgtcatga tcgttactga ccatgccatg gtagagcttg gtttccttga
    19021 tcgtatcatc gaacaactgg accttcgtcg caataaggtt gtttaccaaa tctttgcgga
    19081 tgtagaaccg gatccagata tcacaactgt aaaccgtggt actgagatta tgcgtgcctt
    19141 caaaccagat accatcatcg cactcggtgg tgggtctcca atggatgctg ccaaagtaat
    19201 gtggctcttc tacgagcaac cagaagtgga cttccgtgac cttgtccaaa aattcatgga
    19261 tatccgtaaa cgtgccttca agttcccatt gcttggtaag aagactaaat tcatcgcgat
    19321 tccaactaca tctggtacag gatctgaagt aacaccattt gccgttatct ctgataaagc
    19381 aaacaaccgt aaatacccaa tcgctgacta ctcattgaca ccaactgtgg caatcgtaga
    19441 tcctgctttg gtattgacag ttccaggatt tgttgctgct gatactggta tggacgtatt
    19501 gactcacgcg acagaagcat acgtatcaca aatggctagt gactacactg atggtttagc
    19561 acttcaagcc attaaattgg tctttgaaaa tctcgaaagc tcagttaaga atgctgactt
    19621 ccactcacgt gagaaaatgc ataacgcttc aacaatcgct ggtatggcct ttgccaatgc
    19681 cttcctaggt atttctcact caatggccca taagattggt gcgcaattcc acacaatcca
    19741 cggtcgtaca aatgctatct tgcttccata cgttatccgt tacaacggta cacgtccagc
    19801 taagacagca acatggccta agtacaacta ctaccgtgca gatgaaaaat accaagatat
    19861 cgcacgcatg cttggacttc cagcttctac tccagaagaa ggggttgaat cttacgcaaa
    19921 agctgtctac gaactcggtg aacgtattgg gatccaaatg aattttagag accaaggaat
    19981 tgacgaaaaa gaatggaaag aacattctcg tgaattagcc ttcctggctt atgaagacca
    20041 atgttcacca gctaacccac gtcttccaat ggtagatcat atgcaagaaa tcatcgaaga
    20101 tgcatactat ggctacaaag aaagaccagg acgccgtaaa taattgttta tcagtctaga
    20161 agcaagacaa aaactcaatt tgagggaaag atccagtaat ttttctatga taaaaggcat
    20221 cctatcaagg tttttgaaca cctgatagga tgcctttttg ccctttttga aaaactagaa
    20281 tagaaacaaa atatataata gattgaaact agaatagtac acatctgctt ctaaaacatt
    20341 gttagaattc gatttgactg tcct
//
LOCUS       DAVHSL010000042        19732 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000042 DAVHSL010000000
VERSION     DAVHSL010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.043"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            2..74
                     /locus_tag="VVR39_001526"
     tRNA            2..74
                     /locus_tag="VVR39_001526"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VVR39_001527"
     tRNA            99..171
                     /locus_tag="VVR39_001527"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VVR39_001528"
     tRNA            177..258
                     /locus_tag="VVR39_001528"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VVR39_001529"
     tRNA            277..349
                     /locus_tag="VVR39_001529"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VVR39_001530"
     tRNA            372..443
                     /locus_tag="VVR39_001530"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VVR39_001531"
     tRNA            451..536
                     /locus_tag="VVR39_001531"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VVR39_001532"
     tRNA            546..619
                     /locus_tag="VVR39_001532"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VVR39_001533"
     tRNA            635..708
                     /locus_tag="VVR39_001533"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VVR39_001534"
     tRNA            714..787
                     /locus_tag="VVR39_001534"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VVR39_001535"
     tRNA            801..874
                     /locus_tag="VVR39_001535"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VVR39_001536"
     tRNA            885..974
                     /locus_tag="VVR39_001536"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            988..1061
                     /locus_tag="VVR39_001537"
     tRNA            988..1061
                     /locus_tag="VVR39_001537"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1022..1024,aa:Met,seq:cat)
     gene            1065..1137
                     /locus_tag="VVR39_001538"
     tRNA            1065..1137
                     /locus_tag="VVR39_001538"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1098..1100,aa:Phe,seq:gaa)
     gene            1157..1227
                     /locus_tag="VVR39_001539"
     tRNA            1157..1227
                     /locus_tag="VVR39_001539"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1189..1191,aa:Gly,seq:tcc)
     gene            1263..1336
                     /locus_tag="VVR39_001540"
     tRNA            1263..1336
                     /locus_tag="VVR39_001540"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Ile,seq:gat)
     gene            1343..1430
                     /locus_tag="VVR39_001541"
     tRNA            1343..1430
                     /locus_tag="VVR39_001541"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1377..1379,aa:Ser,seq:gct)
     gene            complement(1564..2001)
                     /locus_tag="VVR39_001542"
     CDS             complement(1564..2001)
                     /locus_tag="VVR39_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6030986.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2252..3187)
                     /locus_tag="VVR39_001543"
     CDS             complement(2252..3187)
                     /locus_tag="VVR39_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU6030987.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3184..4044)
                     /locus_tag="VVR39_001544"
     CDS             complement(3184..4044)
                     /locus_tag="VVR39_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6030988.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIKSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4152..6314
                     /locus_tag="VVR39_001545"
     CDS             4152..6314
                     /locus_tag="VVR39_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6030989.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     ELQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            6349..7608
                     /locus_tag="VVR39_001546"
     CDS             6349..7608
                     /locus_tag="VVR39_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6030990.1"
                     /translation="MEWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7622..8488
                     /locus_tag="VVR39_001547"
     CDS             7622..8488
                     /locus_tag="VVR39_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6030991.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            8502..9335
                     /locus_tag="VVR39_001548"
     CDS             8502..9335
                     /locus_tag="VVR39_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6030992.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            9336..9416
                     /locus_tag="VVR39_001549"
                     /pseudo
     CDS             9336..9416
                     /locus_tag="VVR39_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9554..10996
                     /gene="gtfA"
                     /locus_tag="VVR39_001550"
     CDS             9554..10996
                     /gene="gtfA"
                     /locus_tag="VVR39_001550"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU6030993.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            11134..12327
                     /locus_tag="VVR39_001551"
     CDS             11134..12327
                     /locus_tag="VVR39_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU6030994.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            13013..14992
                     /locus_tag="VVR39_001552"
     CDS             13013..14992
                     /locus_tag="VVR39_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6030995.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15059..16555
                     /locus_tag="VVR39_001553"
     CDS             15059..16555
                     /locus_tag="VVR39_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030996.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16555..17481
                     /locus_tag="VVR39_001554"
     CDS             16555..17481
                     /locus_tag="VVR39_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6030997.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17490..18557
                     /locus_tag="VVR39_001555"
     CDS             17490..18557
                     /locus_tag="VVR39_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030998.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18568..19494
                     /locus_tag="VVR39_001556"
     CDS             18568..19494
                     /locus_tag="VVR39_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6030999.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5685 a         3577 c         4240 g         6230 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttattaacgc gggatggagc agctcggtag ctcgtcgggc
     1021 tcataacccg aaggtcgtag gttcaaatcc tgctcccgca ataaggctcg gtagctcagt
     1081 tggtagagca atggattgaa gctccatgtg tcggcggttc gattccgtct cgcgccattt
     1141 tattgatagt atttatgcgg gtgtagttta gtggtaaaac tacagccttc caagctgttg
     1201 tcgcgagttc gattctcgtc acccgctttg aactttgttc aaattaccaa gttttttaac
     1261 ttgggcgcgt agctcaggtg gttagagcgc acgcctgata agcgtgaggt cggtggttcg
     1321 agtccactcg tgcccattaa ttggagaatt actcaagagg ctgaagagga cggtttgcta
     1381 aatcgttagg tcgggtaact ggcgcaaggg ttcgaatccc ttattctccg ttttaatgag
     1441 agtttgtaac tctctttttt atttttagag acaataaagc ttcagatccg taaaacttaa
     1501 ttgaattact aatctgaagt tatttttatg gctctttgtc aactgtagtg ggttgaagaa
     1561 aagctaagct cgagaaagga caaatttcgt cctttctttt ttgatgttca aagcgataaa
     1621 aatccgtttt ttaaagtttt caaagtttcg aaaaccaaag gcattgcact tgataagttt
     1681 gatgagatta ttggtcgctt ccagtttggc gttagaatag tgtagttgaa gggcgttgac
     1741 aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg
     1801 cttaagattg tcctcaataa gtccgaaaaa tttctctggt tcctttttct tcattagact
     1861 tccacaatca gggcaagatg gagcctcata atccagctta gcgataattt ctttgtgggt
     1921 atccatattg atgatatcta gaatcttgat gtttgggtct ttaatgtcta gtaattttgt
     1981 gataaaatgt aattgttcca tatgattctt tctaatgagt tgttttgtcg cttttcatta
     2041 taggtcatat gggacttttt ttctacacaa aataggctcc ataatatcca tagggaattt
     2101 acccactaca aatattatag agcccgtttt aatgagagtt tgtaactctc ttttttgttt
     2161 ttagagacaa taaaacttca gatccgtaaa acttaattga attactaatc tgaagttatt
     2221 tttatatcgt ttatattata attgtgttat tttacttcca actattgaga gaaatttcgc
     2281 cactatttag ccagatttct tttccgttat cacattgaac taaaagtttt ccattttctg
     2341 agatgtcttt agcaagtccc ttgtagtctt tttgctctag tgtgaaagtg acttcttttc
     2401 ctagaatgaa tgactgtttt ttgtataggt ataatagctc ttctgctggt gtttcgaaga
     2461 aagcacgcca gatttctatg atcaattcat tccttgttat aggagctgta gctttaaata
     2521 agctggcagc tttttctttt aattcctgag ggaagtcttt aatagtgaaa ttgataccta
     2581 ctccaataat gatatctgtg actaagccag tttctacaga ggtcattgct tcagtaagga
     2641 ttcctccaat tttatgattg tttagataga tatcattgac ccattttatg tcgacatcta
     2701 ttaaagttag gttcttaatg gctttgtaga cagctccagc tacaagtagt gtgtaggatg
     2761 gtaatttgtc ataggggaga tttggtttaa gatggagtgt catataaata ccaccttgtg
     2821 gtgagtagaa ggaacgttga aaacggcctc ggcctgctgt ttgataggaa gctagataga
     2881 gggtatttgc ttcatggcct aaatcaattg cttcttttgc atctagttgt gttgattttg
     2941 tttcgggttt aaagctgact ttaattggaa gattttcttc tagaatctct ggaagaataa
     3001 ggtcaccatt catcagttta tatcctctat ttttgatact atcaatttca atgccttctt
     3061 gttctagtcg cttgatggct ttccaaattg ctgttcggct tagggatagt ttttctgcga
     3121 ttttttctcc gctgatatag tcggtttctt tagataggat ttggtagaca gcttggtagg
     3181 atttcataat gttgcctttc ttactagttg gtattgagag tattcttttc ttgtatgact
     3241 tggagtctga ttaaagtatt gtttataagc tttcgaaaaa tggagtggat ctgaaaaacc
     3301 taccgagtat gcaattacct tgatggactc ttgggtattt tcgagaagtt gtctagctcg
     3361 gtgcattcga acgtagagta ggtattcttt gggtgataag gtattaaatt ctttgaatac
     3421 gcttgataag tagcttctgt gaacggatag ttcttttgct aaatcttgaa ttgtaagtga
     3481 ttgaggatag tggctatcaa ttaatcgttt gcattcaaga tagagttggt gggttgatga
     3541 aatattcttt tttttctgat tgggagcaat agttcccaga tgaaacatca gttcatgaag
     3601 ttgtcccatg atatggagtt gagctaattc acttgatttt gtaatctgag cgaagcggac
     3661 aatgtctgag atgagttttg cagtagtctg ggtatgacaa gtttcagatt tgatgagata
     3721 ggattgatca gaaatttggg aaagagcaaa ataatcaggg gctttccctc cagtgattcc
     3781 taaccagtag taggcccaag gttctttact atctgcttga taaaaggtta gttcctctgg
     3841 ttttaataga aagaaatctc cttcttttaa atcaacaatt ttacccttgt aatgaaattt
     3901 tccttgtcct ttagtaatgt aatgtaggac gtatgtatca cgaatggctg gaccaaaaga
     3961 gtaattaggt gtgcattcct catatccata aaagcttagg gcaaggtcga ttgttccagt
     4021 ctggtattct gaaaaaacta acatgtgcta cctcctacct aacattttac catattcttg
     4081 agacattttt ctattttaga aagcgatttc aggtgataaa atagagtcaa taaagtgatg
     4141 aggtgaagta aatgggagtt aggatagaga ataatctatt ttatgttgag agtaaaaatc
     4201 taagtttgat tattgaaaat cgaaatggct acttactttt gaaacattta ggaaagacta
     4261 ttaagaacta taaaggttcc aatagtgttt atgaacgaga ccatgccttt tcaggaaatc
     4321 caacagctac taatcgaacc tttagtttag atactcaacg tcaaattttt ggacaacatg
     4381 gcttaggaga ttttaggaaa ccaaccatac aggttcagca taatgtaact gaagtaacag
     4441 actttcgatt tgtagaagca aagattttaa aaggtcagaa tggtccacag ggcttacctt
     4501 ctccacatag catggacgat acagagactc ttgtcttaat gttagaagat tctaaggctc
     4561 aacttagtct gactttgtat tatactactt ttaataatga tgcgactatt gctagctaca
     4621 gtaaattaga taataatagt aatcaggaag ttgtcatcca taaagatttt tcttttatgg
     4681 ctgattttcc agctgcagat tacgaaatag taactctgca gggtgcttat gctcgtgaaa
     4741 agactgttag acgtcaacag gtagaacaag gaatcttttc gattagttca aaccgaggtg
     4801 cttctggtca tgctcaaaca ccagctcttc tactatgcga acaaggagtc acagaggatg
     4861 ctgggaatgt gtttgctatt caactaatgt atagtggcaa ctttgaagct tttgttcaaa
     4921 aaaatcaatt gaatgaagtt cgggtggcta ttggcattaa tccagaaaac ttttcttgga
     4981 agttagcccc tgaggaatac tttgaaacac cggtagcttt agtgactcat tcagatcagg
     5041 gattaactgg tattagtcat gaaagtcaga attttgtact gaagcacatt atgctaagtg
     5101 aattttctaa aaaagaacgt ccaattctaa tcaataactg ggaagctact tactttgact
     5161 ttcagagaga aaaactgtta gagttagcag atgaagctaa gaaagttggc attgaacttt
     5221 ttgtattaga tgatggttgg tttggcaatc gttttgatga taatcgtgct ttaggtgatt
     5281 gggttgttaa tgaggaaaaa ctgggtggaa gtctagaaag tctgatttca gctatccatg
     5341 aaagaggttt gcagtttgga ctttggttag aacccgaaat gatttctgta gatagtgatt
     5401 tgtatcgtca acatcctgac tgggctattc aggttcctgg ctatgagcat acttattctc
     5461 ggaatcaatt agtacttaat cttgccaatc ctcaggtagt agaatacttg aaaagtgtct
     5521 tagatcaact cctatcttat catgatattg attacattaa atgggatatg aaccgcaata
     5581 tcactaagct agggaatgga ttaacttatc tagagacaca gatgcaatct catcagtaca
     5641 tgctggggct ttacgaactc gtttcttatc tgacagagaa gcacagccat attctctttg
     5701 agtcctgctc tggtggtggt ggacgaaatg atcttggtat gatgcgctat ttcccacaag
     5761 tctgggctag tgataatact gatgccattg cacgtttacc aattcaatac ggttcatcct
     5821 atctctatcc aaccatttct atgggggctc atgtgtcagc agtaccgaat catcagatgg
     5881 gacgaatgac accattagaa acacgtggcc atgtagcaat gatgggaaat ttgggctatg
     5941 agcttgattt gacaaattta tcagatgaag agaaagctac gattgctaat caggtgaact
     6001 tgtataaaga attacgacca gtagttcagt taggacagca gtatagacta attaatcctg
     6061 atactgcatc caatgaagca gctgtacaat ttaattacgg aaatcaaacg attgtaacct
     6121 acgttcgcgt tttatctgtt gtagagacca tggaaacaac tttaaaatta aaagatttgg
     6181 atgaagaggg actatatgaa ttacaggaaa atggcgaagt ttactcaggt gcagaactaa
     6241 tgtatgcggg cctaactgtt atcttatccc aaggagattt tttgagtaga cagtatattt
     6301 ttagaagact atgataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat
     6361 aaaaaaatcg gacttcttgc aactacaggt ttagctttgg ttgggctcgg cgcttgctcc
     6421 aactatggta aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa
     6481 atgaccaaaa ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag
     6541 gtcaaagtcg tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga
     6601 gatgtgcctg atgtggtcaa tatttaccca cagtccatcg aactgcaaga atgggcaaaa
     6661 gcaggtgtct ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatggctac
     6721 gctgaaaaat atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc taatgcttat
     6781 ggaatttact acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg
     6841 gatgaatttg aacagttagt caaagatatc gttgctaaag gacaaacacc atttggaatt
     6901 gcaggtgcag atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca
     6961 ggtggaggaa aagaagcaaa tcaatacctt cgttattctc aaccaaatgc cattaaattg
     7021 tcggatccga ttatgaaaga tgatatcaag gtcatggaca tccttcgcat caatggctct
     7081 aagcaaaaga actgggaagg tgctggctat accgatgtta tcggagcctt cgcacgtggg
     7141 gatgtcctca tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg
     7201 aactttaaga ttgggacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt
     7261 ggtgcgggag acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat
     7321 gcctttgtgg aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga
     7381 tctccaacag cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg
     7441 accgaatatg cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa
     7501 gcagacttcc ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc
     7561 aatgatttga atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac
     7621 tatgaaaaaa gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt
     7681 acaagcaatt ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg
     7741 gacaggattg acttacaact acaaatttgt cggcttaaac aactttaagc tcctcttcat
     7801 ggatccaaaa ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt
     7861 tggtgagatt gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca
     7921 aaccttcttc cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt
     7981 gatcttcaag caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga
     8041 atttctccaa accagtcttt tagggactaa gtggggagca atctttgcgg ctgtctttgt
     8101 ccttctttgg caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat
     8161 tccaactgag attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg
     8221 gaacattgaa ttgccttact tgctaccaag tgtctctata gtctttatcc tagccctaaa
     8281 aggtgggctg actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc
     8341 cacaacctca cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta
     8401 tgccaatgcc attgccgtaa tcttgttctt cttaattgta gtgatttcga tcatccaatt
     8461 gagagtatct aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa
     8521 aagccctgat tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc
     8581 tccttgctac cctctttagt tccttcaaat ccactaagga tattgtagat aatttctttg
     8641 gctttccaac caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag
     8701 gctattattg gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta
     8761 tccctatggc agcctactcc atcgctcgca atatgagtaa aagaaaagcc tttaccatca
     8821 tgtataccct cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta
     8881 cggttatgat gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga
     8941 cctatgcgat tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag
     9001 aaagtctgga tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca
     9061 tcatcttccc aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gccctttggt
     9121 tctggaatga cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc
     9181 tgcctttgtt ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg
     9241 cctcttacgt ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata
     9301 tcatcgcagg aataagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa
     9361 ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgacg
     9421 aagtcagtaa ccatacctac ggtaaggcga cactgacgtg gtttgaagag attttcgaag
     9481 agtataacat gaatttgatt tacgaagcca gatcatatga gacttggctt caattagaaa
     9541 aaggagagta atgatgccaa ttcaaaataa aaccatgttg attacctatt ctgatagcct
     9601 tggaaataat cttaaagact tatatgataa tttggaagag cattttggag atgctattgg
     9661 aggagttcac cttttaccat ttttcccatc aacaggtgat cgtggatttg cgccagttga
     9721 ctacgacgaa gtggactcag cttttggtga ttgggaggat gttaagcgtt taggtgagaa
     9781 atattatctt atgtttgatt ttatgattaa tcatatttct cgtcaatcca agtattataa
     9841 ggactatcaa gaaaaacatg aagccagtga atttaaagat ctctttttaa actgggataa
     9901 gttttggcca gaaaaccgtc cgacacagtc tgatgtagat ttaatttaca agcgtaagga
     9961 tcgtgcacca aagcaagaga ttgtgtttga agatggttca gtggaacatt tgtggaatac
    10021 ctttggtgag gagcagattg atcttgatgt gaccaaagaa gtaactatgg aatttatccg
    10081 taagaccatt cagcacttgg caagtaatgg gtgtgatttg attcgtctag atgcctttgc
    10141 ttatgcagtg aagaaattgg atactaatga tttctttgtg gaaccagata tttgggattt
    10201 attggacaaa gttcgagata tcgctgctga gtatgggaca gagattttac ctgagattca
    10261 tgaacactat tcgattcagt ttaaaatagc agaccatgat tactatgttt atgattttac
    10321 tcttccaatg gtgacacttt atactcttta cagttccaga acagagcgtt tggctaagtg
    10381 gttgaagatg agcccgatga agcaatttac gacgctagat acccatgatg ggattggagt
    10441 agtagatgtc aaggatatcc tgaccgatga ggagattgac tatgcttcaa atgaactcta
    10501 taaggttgga gccaatgtca aacgtaagta ctctagtgcc gagtataaca acttagatat
    10561 ctaccaaatc aattcaacct actattcagc gcttggagat gatgatgtca agtattttct
    10621 cgctcgtcta attcaagctt ttgccccagg tattcctcag gtttactatg tgggtctatt
    10681 agcaggcaag aatgacttga aattattaga agaaactaaa gaaggtcgaa atattaatcg
    10741 tcattactat agcaacgagg aaatagcaaa agaagtgcaa cgacctgttg tgaaggccct
    10801 tctcaatcta ttttctttcc gtaaccgttc agaagccttt gatctagaag ggactactga
    10861 gatagagaca ccaacagctc acagcattgt aatcaaacgt caaaataaag ataagtccgt
    10921 aacagcagta gcagaaattg atttgcaaaa tcagacttat cgggtaattg agaatggagt
    10981 tgaagtatca ttttgaagcc ttgatatggt ggataaaata gggtttttat tttggaaaac
    11041 gtttcctttg ttttcaaatt gctaaaaaag tggtacaata taggatagct tactattatc
    11101 tgaatcagct gatttggaga gaaaggattc attttgaaat caataggctt tattgaaaag
    11161 ctgaaggggt tgtctagtaa agagctgatt ttattgggaa ttatcctaag tatcttttta
    11221 cccttttatc tttttgtagt tgtactctgt ttatatatta tcagtttgat ttttacagga
    11281 gacatgaaaa gtattcttca gaaaatgggg gagcatccga tgctgcttct ttttcttagc
    11341 tatagtactg ttatatccat tcttgcacaa aattggatgg gtcttgtggc ttcagtagga
    11401 atgtttctat ttactatttt ctttttgcac tatcagtcga ttttatccca taaattcttt
    11461 cgattgattt tgcagttcgt cttgtttggt agtgtcttgt cagctgcttt tgccagttta
    11521 gaacatttcc aaattgtgaa gaaatttaac tatgcttttc tttcacccaa tatgcaggtg
    11581 tggcatcaga accgggcaga agtgaccttc tttaatccta attattatgg aattatttgt
    11641 tgtttctgta ttatgattgc tttctatctg tttacaacga ccaagttgaa ttggttgaaa
    11701 gtattctgtg tgattgcagg ctttgttaat ctctttggtt tgaactttac tcaaaatcga
    11761 actgcctttc ctgctattat cgctggagca attatctatc tctttacgac tattaaaaac
    11821 tggaaggcct tttggcttag tattggggtc ttcgcgattg gtttgagttt cctcttttct
    11881 agtgatttgg gagttcgaat gggtacttta gactcttcta tggaagaacg catttctatc
    11941 tgggatgctg ggatggcctt gtttaagcaa aatccttttt ggggtgaagg gccattgacc
    12001 tatatgcact cttatcctcg gatacatgct ccttatcatg aacatgccca cagtctttat
    12061 attgatacga ttctgagtta cggaattgtg ggtaccattt tattagtttt gtcttctgtt
    12121 gctcctgttc gcttgatgat ggatatgagt caggagtcgg ggaaacgtcc gattatcggc
    12181 ctttatctat ctttccttac agtggttgct gtgcacggaa tttttgactt ggctctcttc
    12241 tggattcagt caggctttat tttcttgcta gttatgtgca gtattccatt ggagcatcga
    12301 atgttggtat cggacatgac ggattaagtt ttataagttt gaaatcttct accttgggta
    12361 ggagattttt ttatacgatg ggcatgtcgt gcatctgagg tgtaagtcct ctgtagggat
    12421 ccactaccgg tgaatacaat agcgctcccc aagcctgact atcgtgaggt agcggattaa
    12481 aatggtctgg ggatagatcg ttttaagtct gacgcaggaa ataagaattg tcagagaaag
    12541 caatagtgaa atcgtaggct atgaatagaa acgtgatagc gaggagcata tagtggataa
    12601 ggtagcgaga aattttaaag tataaaagat agtcttaatc tatatatgta aatcacaaaa
    12661 gtaattgaat tcggaataag gttggtgtga aaagacatag taaactgaat cttgaatact
    12721 agaatgatac ttctacaata ttgttataat ttaatttgaa ttccaaaatc acattgttcc
    12781 gtccgtattt cattttactg tatgtcttcc taaactccaa agtttctgcg tcaaatttcc
    12841 tattttcact gtagtctttg acacttcgaa cgacaatttg aatcatatat tcaaaaaaaa
    12901 tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt tgtttgattt ttaatggata
    12961 atgtgatata atggttgtca atctataatt cacataaaca gaggagtaga aaatgaaaaa
    13021 aaatcgtgta tttgctacag caggtcttgt tttattagca gcaggtgtac ttgcagcatg
    13081 cagttcttca aaatcatctg attcatcagc ccctaaagct tatggctatg tttatacagc
    13141 agacccagaa accttggact acctgatttc aagtaaaaat agtacaacag tagtgacttc
    13201 aaatgggatt gatggtttat tcactaacga taattacggt aatcttgctc ctgcagttgc
    13261 agaggattgg gaagtctcta aggatggttt gacctacact tataagattc gtaaaggggt
    13321 taaatggttt acctctgatg gagaagaata tgcagaggtg acggctaaag atttcgtgaa
    13381 cggtttaaaa cacgcagcag ataaaaaatc agaagctatg tatttagctg aaaattcggt
    13441 taaaggcttg gcagattatc tatcaggaac ttcaacagat ttttcaacag ttggtgtcaa
    13501 ggcggttgat gattatacgt tacaatacac tttgaaccag cctgaaccgt tctggaactc
    13561 taagttgacc tattctattt tctggcctct gaatgaagaa ttcgaaacat caaaaggaag
    13621 cgattttgct aaaccaacag atccgacatc cttgctttat aatggtccat tcttgttgaa
    13681 agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat gagcaatatt gggataaaga
    13741 aaatgtccac ctagatacta tcaatctagc ttactatgat ggatcagatc aggagtcgct
    13801 agagcgtaac ttcactagtg gagcttatag ttatgcccgt ctttacccta ccagctccaa
    13861 ctattctaag gttgcagaag aatacaagga caatatctat tacacacaat caggctctgg
    13921 gattgctggt ctgggtgtga atattgatcg ccaaagttac aactatactt ctaaaactac
    13981 agattcagag aaagtagcta ctaagaaggc attgcttaac aaagatttcc gtcaagcctt
    14041 gaattttgct cttgatcgct cagcttactc agctcaaatc aatggtaaag atggagcagc
    14101 tttagcagtt cgtaatttat ttgtaaaacc agactttgtt tcagctggtg agaagacctt
    14161 tggtgattta gtcgctgctc aacttcctgc ttatggtgat gagtggaaag gtgtgaattt
    14221 agctgatggg caggatggtt tattcaatgc tgacaaggcc aaggcagagt ttgcgaaagc
    14281 taagaaagct ttagaagcag acggcgttca gtttcctatt catctggacg ttccagtaga
    14341 ccaagcatca aaaaactaca tatctcgtat tcagtccttt aaacaatctg tagaaacagt
    14401 tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg acaagtgatg aattccttaa
    14461 tattacttac tatgctgcca atgcttcatc tgaggattgg gatgtatcgg gaggagtttc
    14521 atgggggcca gactatcaag acccatctac ttacctggat attttaaaaa caactagcag
    14581 tgaaactaca aaaacatatt taggatttga taatccaaat agcccttcag tagttcaagt
    14641 tggtttgaaa gaatacgata aattagttga tgaagctgcc aaagagacaa gcgacttgaa
    14701 tgtccgttat gaaaaatatg cagcggctca agcatggttg acagatagtt cactctttat
    14761 tcctgctatg gcttcttctg gtgcagcacc agtgctttca cgaattgttc catttactgg
    14821 agcttctgcg caaacaggct ctaaggggtc agatgtttac ttcaaatatt tgaaattaca
    14881 agataaagtg gtgactaagg aagagtatga aaaagctcgt gaaaaatggt tgaaagaaaa
    14941 agctgaatca aatgagaaag ctcaaaaaga attggcaagt catgtgaagt aaataatttc
    15001 taatagaact ttctctccat gaggagaagg ttcttttggg atttttaaag gaaataatat
    15061 gaaaaaatat atttttatgc gtgttttgcg gtcattggtt tcgattttct tagtaacgac
    15121 tttgacctac acgattatct ataccttggt tcctcgaaaa ttgattttca agcaggatcc
    15181 taactataat aaaattgcga caacggctga taaacgtgat aactatgaaa atactgtgtt
    15241 tgagcgtatg ggctacattg agtattacga tactaaagag ttgcaagaaa aggcaagtag
    15301 catggattct tctgtaacag tagaagcaaa tgcgaccaat aaagctattt atgaaaagta
    15361 catcaatcaa ttaggtcatg gttggacttt gggagaattt actgaaagtg gtcaattcta
    15421 tgctactcgt gaaattccaa tttttgaacg tgtttttcac ttctatgcta acttgattga
    15481 cattgaccat acaaataaaa tccaagaccc tgaaaatcca gacttgaaac gctaccttcg
    15541 ttttgaaaat gatccagcta tcggatggtc attggtcggt tcaggaacta aacataaata
    15601 tctcttgtac tttaacagtc agttcccatt tgttcatcaa aactttgtga acttgaattt
    15661 aggtgactct tacccaacct atgctaatac accagttctt caggttatta ctcaaggtca
    15721 aggacaaacc aaaactgccc aagttcagtt cccaacaggt aagaaaacgt cttctgtaaa
    15781 tatttactca agaacctaca agtcacctag tcaggctgac tctcgtgaag tagctagcta
    15841 tgggaaagat gatccttata cagcgactga aagtaattac caatatccat ctatgattgt
    15901 cagctctgct attactggtt tgattggttt ggttcttgcc tatgctcttg ccgtgccact
    15961 tggttcagcc atggctcgtt tcaagaacac ttggattgat agcctctcaa cagggacttt
    16021 gaccttcttg cttgctcttc caacgattgc cttggtttac atcgttcgat tgattggatc
    16081 atctattgcc cttccagatt cattccctat cttgggagct ggagattggc gttcttacgt
    16141 tttaccagca gtcatccttg gtttgttggg tgctcctgtt acagccattt ggattcgtcg
    16201 ttacatgatt gacttgcaat ctcaagactt tgttcgtttc gctcgtgcaa aaggtttgtc
    16261 tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc atggttccgc tggtttcagg
    16321 aattcctggt gccattattg gggttatcgg tggtgcaacc cttactgaaa cagtcttcgc
    16381 cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa gcatctaata actctatggt
    16441 cgttggtctt gtcttcatct ttacatgtat ttctatcttc tcacgtcttt tgggagatat
    16501 ttggatgact attattgacc cacgtattaa attgactgag aaaggaggca aataatgtct
    16561 acaatcgata aagaaaaatt tcagtttgta aaacgtgacg attttgcctc tgaaactatt
    16621 gatgcgccag catattctta ctggaaatca gtgtttaaac aatttatgaa gaaaaaatca
    16681 actgtagtca tgttgggaat cttggtagcc atcattttga taagtttcat ctacccaatg
    16741 ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg actttagtgt tcgttatatc
    16801 aagccaaatg cggagcattg gttcggtact gacagtaacg gtaaatcgct ctttgacggt
    16861 gtctggttcg gagctcgtaa ctccatcctc atttctgtga ttgcgacagt gattaacttg
    16921 gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa aatcagttga ccgtgtcatg
    16981 atggaagttt acaacgtcat ctcaaacatc ccacctcttt tgattgttat tgtcttgact
    17041 tactcaatcg gagctggatt ctggaatctg atttttgcca tgagcgtaac aacatggatt
    17101 ggtattgcct tcatgatccg tgtgcaaatc ttgcgctatc gtgacttgga atacaacttg
    17161 gcgtcacgta ctttgggaac accaaccttg aagattgttg ccaaaaatat catgcctcaa
    17221 ttggtatctg ttattgtgac aaccatgact caaatgcttc caagctttat ctcatacgaa
    17281 gccttcttgt ctttcttcgg tcttggatta ccgattacag tgccaagttt gggtcgtttg
    17341 atttcggatt attcacaaaa cgtaacaacc aatgcttact tgttctggat tccattgaca
    17401 acccttgtct tggtatcctt gtcccttttc gtagttggtc aaaacttagc ggatgctagt
    17461 gatccacgta cacatagata ggagtagaaa tgacaaaaga aaaaaatgta attttgactg
    17521 ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt attgacagcc attcgcggcg
    17581 tttcccttga actagtcgaa ggagaagtat tagccttggt aggtgagtca ggatcaggta
    17641 aatctgtttt gacaaagacc ttcacaggta tgctcgaaga aaatggtcgt attgcccaag
    17701 gtagtattga ctaccgtggt caggacttga cagctttatc ttctcacaag gattgggaac
    17761 aaattcgtgg tgctaagatt gcgactatct tccaggaccc aatgactagt ttggacccca
    17821 ttaaaacaat tggtagtcag attacagaag ttattgtaaa acaccaagga aaaacagcta
    17881 aagaagcgaa agaattggcc attgactaca tgaataaggt tggcattcca gacgcagata
    17941 gacgttttaa tgaataccca ttccaatatt ctggaggaat gcgtcaacgt atcgttattg
    18001 cgattgccct tgcctgccga cctgatgtct tgatctgtga tgagccaaca actgccttgg
    18061 atgtaactat tcaagctcag attattgatt tgctaaaatc tttacaaaac gagtatcatt
    18121 tcacaacaat ctttattacc cacgaccttg gtgtggtggc aagtattgcg gataaggtag
    18181 cggttatgta tgcaggagaa atcgttgagt atggaacggt tgaggaagtc ttctatgacc
    18241 cttgccatcc atatacatgg agtctcttgt ctagcttgcc tcagcttgct gatgataaag
    18301 gggatcttta ctcaatccca ggaacacctc cgtcacttta tactgacctg aaaggggatg
    18361 cttttgcctt gcgttctgac tacgcaatgc agattgactt cgaacaaaaa gctcctcaat
    18421 tctcagtatc agagacacat tgggctaaaa cttggcttct tcatgaggat gctccaaaag
    18481 tagaaaaacc agctgtgatt gcaaatctcc atgataagat ccgtgaaaaa atgggatttg
    18541 cccatctggc tgactaggag gaaggaaatg tctgaaaaat tagtagaaat caaagattta
    18601 gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg ttaaaaatgc taacttcttt
    18661 atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg gtagtgggaa aacaactatt
    18721 ggtcgtgcta tcatcggtct aaatgataca agtaatggag atatcatttt tgatggtcaa
    18781 aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat tgattcgtcg aatccagatg
    18841 attttccaag accctgccgc aagtttgaat gaacgtgcga ctgttgatta tattatttct
    18901 gaaggtcttt acaatcaccg tttatttaag gatgaagaag aacgtaaaga gaaagttcaa
    18961 aatattatcc gtgaagtagg tcttcttgct gagcacttga ctcgttaccc tcatgaattc
    19021 tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct tggtcatgca accagacttt
    19081 gttattgcag atgagccaat ttcagccttg gacgtttctg tacgtgccca agtcttgaac
    19141 ttgctcaaaa aattccaaaa agagctcggc ctgacctatc tcttcatcgc ccatgacttg
    19201 tcggttgttc gctttatttc agatcgtatc gcagttattt acaagggtgt tattgtagag
    19261 gttgcagaaa cagaagaatt gtttaacaat ccaattcacc catatactca agccttgctt
    19321 tcagcggtac caatcccaga tccaatcttg gaacgtaaga aggtcttgaa ggtttacgat
    19381 ccaagtcaac acgactatga gactgataag ccatctatgg tagaaatccg tccaggtcac
    19441 tatgtttggg cgaaccaagc cgaattggca cgttatcaaa aaggactaaa ctagtaatgg
    19501 ttttataatt tccatgtcaa tttttatgga aattaggctc tttgtcaact gtagtgggtt
    19561 gaagtcagct aagctcgaga aaggacaaat ttcggctctt tgtcaactgt agtgggttga
    19621 agaaaagcta agcttgagaa aggacaaatt tcatcctttc ttttttgatg ttcagagcga
    19681 taaaaatccg ttttttgaag ttttcaaagt ttcgaaaacc aaaggcattg cg
//
LOCUS       DAVHSL010000043        19146 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000043 DAVHSL010000000
VERSION     DAVHSL010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.044"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(114..389)
                     /locus_tag="VVR39_001557"
     CDS             complement(114..389)
                     /locus_tag="VVR39_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU6031000.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(496..1335)
                     /locus_tag="VVR39_001558"
     CDS             complement(496..1335)
                     /locus_tag="VVR39_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6031001.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGHILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1477..2325
                     /locus_tag="VVR39_001559"
     CDS             1477..2325
                     /locus_tag="VVR39_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6031002.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2418..3335)
                     /locus_tag="VVR39_001560"
     CDS             complement(2418..3335)
                     /locus_tag="VVR39_001560"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU6031003.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3773..3978
                     /locus_tag="VVR39_001561"
                     /pseudo
     CDS             3773..3978
                     /locus_tag="VVR39_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4183..4476)
                     /gene="rpmA"
                     /locus_tag="VVR39_001562"
     CDS             complement(4183..4476)
                     /gene="rpmA"
                     /locus_tag="VVR39_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU6031004.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4493..4837)
                     /locus_tag="VVR39_001563"
     CDS             complement(4493..4837)
                     /locus_tag="VVR39_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU6031005.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4853..5167)
                     /gene="rplU"
                     /locus_tag="VVR39_001564"
     CDS             complement(4853..5167)
                     /gene="rplU"
                     /locus_tag="VVR39_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU6031006.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5203..5290)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5355..6053)
                     /locus_tag="VVR39_001565"
     CDS             complement(5355..6053)
                     /locus_tag="VVR39_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU6031007.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6455..6754
                     /locus_tag="VVR39_001566"
     CDS             6455..6754
                     /locus_tag="VVR39_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU6031008.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(7095..8069)
                     /gene="pta"
                     /locus_tag="VVR39_001567"
     CDS             complement(7095..8069)
                     /gene="pta"
                     /locus_tag="VVR39_001567"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU6031009.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKVKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(8113..9009)
                     /locus_tag="VVR39_001568"
     CDS             complement(8113..9009)
                     /locus_tag="VVR39_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6031010.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(9006..9824)
                     /locus_tag="VVR39_001569"
     CDS             complement(9006..9824)
                     /locus_tag="VVR39_001569"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU6031011.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(9808..10479)
                     /locus_tag="VVR39_001570"
     CDS             complement(9808..10479)
                     /locus_tag="VVR39_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU6031012.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10607..11176
                     /locus_tag="VVR39_001571"
     CDS             10607..11176
                     /locus_tag="VVR39_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU6031013.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            11286..12245
                     /locus_tag="VVR39_001572"
     CDS             11286..12245
                     /locus_tag="VVR39_001572"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6031014.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            12255..13370
                     /locus_tag="VVR39_001573"
     CDS             12255..13370
                     /locus_tag="VVR39_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6031015.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            13375..13722
                     /locus_tag="VVR39_001574"
     CDS             13375..13722
                     /locus_tag="VVR39_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU6031016.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            13730..13945
                     /locus_tag="VVR39_001575"
     CDS             13730..13945
                     /locus_tag="VVR39_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6031017.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            14028..14669
                     /locus_tag="VVR39_001576"
     CDS             14028..14669
                     /locus_tag="VVR39_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU6031018.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            14687..15376
                     /locus_tag="VVR39_001577"
     CDS             14687..15376
                     /locus_tag="VVR39_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6031019.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(15373..16053)
                     /gene="radC"
                     /locus_tag="VVR39_001578"
     CDS             complement(15373..16053)
                     /gene="radC"
                     /locus_tag="VVR39_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU6031020.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(16096..18387)
                     /gene="pcrA"
                     /locus_tag="VVR39_001579"
     CDS             complement(16096..18387)
                     /gene="pcrA"
                     /locus_tag="VVR39_001579"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU6031021.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYIDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTKEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(18570..19146)
                     /locus_tag="VVR39_001580"
                     /pseudo
     CDS             complement(18570..19146)
                     /locus_tag="VVR39_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5853 a         4047 c         3486 g         5760 t
ORIGIN      
        1 acaatatttt cggaacattc aactttttaa ctctatttat tactaaattt cataattaaa
       61 aagcctactg accaagctag aaagcttgat acaataggct ttttaaagac tgattattta
      121 acagcgtctt taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc
      181 atttctttac cagtttgtgg gttgcgacct ttacgttctg cgcgctcacg aacttcaaag
      241 ttaccaaaac cgatcaactg aactttttca ccagctgcaa gatagtcagc tactgctgca
      301 aatacagctt caactgctgc tgctgagtct ttcttagtca attctgtagc ttctgctact
      361 ttagcgatca aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta
      421 acaaatataa tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc
      481 attttattta tttttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
      541 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
      601 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
      661 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
      721 agttccacga cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacagcacg
      781 gatattgaga agagagctca acaagccagt tacacggcta attcgtccac ctttgacaag
      841 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
      901 agataaaatt gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
      961 gaatttcagg gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag
     1021 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
     1081 aagaatatgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
     1141 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
     1201 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
     1261 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
     1321 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
     1381 ctaattatat caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa
     1441 tttgatataa tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt
     1501 tttaccattt tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc
     1561 catcatctct ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa
     1621 atccctgttt ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag
     1681 atttttggag ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccggctgg
     1741 ttagcttttt ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca
     1801 gcccttatag cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt
     1861 acaactggcg gaactgatat tctagctcgt attctcaaca aatacactca tatatccata
     1921 ggaaaactgc tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag
     1981 gatttgagat tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat
     2041 ttgattggtg aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac
     2101 caacttgcta aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttctggtcaa
     2161 ggctactata gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt
     2221 gtgaaaacga aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa
     2281 gcccatgaaa tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg
     2341 tgacctcaaa agttagacta aatcatctat cttttgggtt acagacaacc tcttttttat
     2401 tttatttact caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga
     2461 tccactaatt ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa
     2521 accatgacgg tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt
     2581 gcttcttctc catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt
     2641 ctttgaatct caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa
     2701 agcactaaat tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaaccacc
     2761 atacctcttg atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct
     2821 aaaatagctt gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga
     2881 acaatgataa cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa
     2941 ccaaatgtat aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt
     3001 gcaaagaatt cttgtgcagt gagactagcg aattgactac taaaatcaag gagatataat
     3061 tcttctacac cttcgcgctt taattttctt tcacgttcag cagggttcaa aatatgcaaa
     3121 aacaaatctg gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg
     3181 acgataggta ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc
     3241 cccttatgta tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata
     3301 tctttttggt tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc
     3361 tatttctgga acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca
     3421 aaaagcactt tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact
     3481 tgtaggacat cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg
     3541 tcatactatg cttatgtatg aaaaagcaat gcaactaact cctgagaact ttaaattact
     3601 aattggtgcc gaaaaggtag aatttagaat cgaggtacac ctatggctgt aaaatttaca
     3661 aaatgagaca acttgggcaa gatgtttgaa gaatttccta aactccctga tttgaagcaa
     3721 gtcactttcc ctgatgacaa agaaaaaagc caaaacagca aagaaaaact agatgactgc
     3781 tttccaacaa ctcccatcta gtgtgcttca gactgggcta tttttctctc catctgttag
     3841 cttggattct cagacagttt cagctaaaga atatcttttc ccttatcaga aggaacggct
     3901 caaaccattc agacaagtga agggacgaca agccaatatt tgaaaccaga tagcagttct
     3961 tatagtcaat tgaaataaaa tctgaagaaa tcgagtagga aactcatatc aatttttaac
     4021 agtgttctat tccagattca atccactata catattaaaa agtatgggta ccaaaacaaa
     4081 aaaacaggct ctccgaaaac tcggaaagcc ttattttaag ctgtttctag cttcctcacc
     4141 tttacatttc aaggttcggg ataaaaggtt caatggacct ttttatttag cgattgggta
     4201 aacagaaact tgttttttat cgcgtccttt acgttcaaag cgtactacgc cttcaacttt
     4261 agcgaacaaa gtatcgtctc caccacgacc aacgtttaca cctggataga tgtgtgtacc
     4321 acgttgacgg taaaggattg atccacctgt tacagtttgt ccgtcagctg ctttagctcc
     4381 aagacgtttt gcttgtgaat cacgtccgtt tgatgtagaa cctccacctt ttttgtgggc
     4441 gaaaagttgc aagttgttaa gagtcatttt taacataatg ttttcctccg tgttagtttt
     4501 ctgtgataac tctggtttgg acgaactcag aatagttctc cgataagttt gccataccta
     4561 agaaaaatga ttcaaagaat aactgggtca tttctctctg gtgtgaagga agatcttttg
     4621 gtatttcaac catcagatag ccaccttcat cttcgtttaa ttctaggatt ggttcatagc
     4681 ctgcaaattt ctcaatagaa ttgataaagt taatggcaag cgtagaaacc gatgcacaca
     4741 cgacatctaa gccgtattcg ccactctcgg cgtgtccagt aatttccgca ctcctcagct
     4801 cgccatcttc ggctctctca aagactgcct gtatcatgtg ttctccttaa aattaagcgt
     4861 tgattgcgtt gatgacaact tttgtatatg gttgacggtg accttgttta cggtggctac
     4921 cttttttagg tttgtacttg taagtaacca ctttcttttg ttttccttgt ttttcaacag
     4981 ttccaactac agtagctcca gcaacaagtg gagttccgac aacagtgttt tcaccaccaa
     5041 caagaacaac ttcgttaaaa gtaacttctt gaccagcttc aacgttcaat ttttcaacgt
     5101 aaactgcttg accaacttca actttaactt gttttccgcc agttttgata attgcgtatg
     5161 tgctcattat gcacctccta tgatttttat gggtttcccc gattttttgt gaagactcgc
     5221 ctagcatcgt gggacgaacc acttaaactt gaataatcaa gcaacgatgt tcgtgcggtt
     5281 gcacaggatc gtgcatagtc aactcttcaa gtatagcata tctcctattt tcttacaagt
     5341 aataacacct aaaatcaagc tttttctttt acttttttct gccaagaggc aaaaagcatg
     5401 ctgaggtaaa aaacgctcat cataatagga acaccaagaa tggtcttttc atgatagaaa
     5461 atcgtcaaat aggctgaaaa gacaacgcca aggacaaaac tactaagcag gctaacaaat
     5521 atgaatcctt cacgcaaaaa aggagtgtgc ttggttcgga aataatctcc aaaagccagc
     5581 atggtccgtt tgatattccc tgtcataaaa gcgttattat aggcaatacc cgacacttct
     5641 ccaaaagcag ttgtcaccag tcccatacag aaggccaagg gcggcactag atagatatta
     5701 tccacagttt gcggcacaaa agcaataatg attgataaga ttgccaaggg aatcaaggac
     5761 agaataggtt ttttcacaat tctcaatttt tccttataaa tcgttaataa aaagactccc
     5821 atcataaacg ctagcaaggt gagaaccttg tccctaacat ccgaaacatt atttttaatt
     5881 aattctactg aaagaaagac aacatttcca gtttgtccag ctacaagggt attcccgcga
     5941 acaataaaag tgtaagcatc cacatatcca gcacaaaacg tcaaaaaaag tgctaacctt
     6001 ttagactgac gtgatatttt tcttataggt aataacctca ttttacctcc cattgtattt
     6061 tctcttagaa atattgtacc attttctttc taaaaaatcg taggctacca tttagatttt
     6121 actattagca taaaaataat aatagacaac tatttatcca aaaatagata gatgtaacat
     6181 gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact agaatagagc
     6241 cctcttagca aaaatcatta ttttaattta tttctaatca ctccttgaca taaataactc
     6301 tcaccaataa aagactatgt cttaaaaaaa tggtataata aaatcaatac ttgggcttga
     6361 tggctatgct actaataaca attaggagag aaaatcaggc acttgttaac aacaaggatt
     6421 atccccttga gatgaaagga actttagaaa tcttatgatg aacatgcaaa acatgatgcg
     6481 tcaagcacaa aaacttcaaa aacaaatgga acaaagccaa gctgaacttg ctgctatgca
     6541 atttgttggc aaatctgctc aagatcttgt ccaagcgacc ttaactggcg ataagaaagt
     6601 tgtcagcatt gatttcaatc cagctgtcgt tgacccagag gaccttgaga ctctttctga
     6661 tatgaccgtt caagccatca actctgctct tgaacaaatc gatgaaacta ccaagaaaaa
     6721 actgggtgct ttcgctggga aattaccttt ctaaaaacaa ggagctagaa caatgcttgt
     6781 cgataacaaa gattaagaaa ggtgcaaaaa ttataaaaaa cgcataatag caggtgtcaa
     6841 gacacttaat attatgcgtt ttctcatgaa aaattctctt ttcatactca tttaaaatca
     6901 aaaagggaaa ttatcgtttt acggacatac atattacaga tttctatagg tcgtgtatag
     6961 acaggatatc atcgcttgga agttttcctt tttgacacca atcagtaatt tagttctcag
     7021 gaattaatgg cagtgctttt cgtacatagt ttcataacta cagtatagca tagtatatcg
     7081 ctttatagtt ttcactattg atgaactgct tgagctgctg tgatgagggt caacttgtaa
     7141 acatcatctg cattacatcc acgagaaaga tcattaactg gcttgtttaa accttgcaaa
     7201 acaggtccta cagccgcaaa gccacccagg cgttcagcca tcttgtaacc gatatttcct
     7261 gcctcgatac ctgggaagat gaagacattt gcttgaccag ctaccgtact tccaggagct
     7321 ttcagagctg cagtttcagg aacaaaggct gcatcaaatt gcaactcacc atcgatttca
     7381 aggtcaggac gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc aacgctttca
     7441 ccaaaccctg aacctttagt agaatagctc aacatggcaa ttttaggttc gatgccaaac
     7501 atcttagctg tgattgctga gttgatggca atttcagcca aggcttctgc atctggattg
     7561 atgttaatgg cacagtctcc aaataggtaa cgttccgtac cacgaaccat gaggaaggct
     7621 cctgaagtac gagttacatt tggacgagtt ttgatgattt gtagagctgg acgaactgtt
     7681 gaagctgttg agtgaatcgc tcctgacacc attccatcaa ccaagcccaa gtaaaccaac
     7741 atcacaccaa agtagttgac atcttcaacc aaaaccttgc gtacatcttc ttcagtcatt
     7801 ttgcccttgc gacgctccac caaggcagaa accatttctt caaattgagg ataatgttga
     7861 gggtcgatga cctcataacc atccatgatt ccttcaattt caagataaat tttaactttt
     7921 tcaggatttc caagcaaaac aggaatcact tctgtttctt ttactaagcg ttttgttgct
     7981 tgaagaatac gaggctcttc cccttcaggg agaacgatac gagcattttt accaacaagg
     8041 ttggctttga gactttcaaa aacttccatg agttttctcc tttaagataa taattatact
     8101 ctgagacagt ttttatagag tattagttga taactgggta ataaggttac tgaaatcatc
     8161 cggcaaggga ctttctaact gcaagtcttg ctctaaaaat ggatgataaa aggataggta
     8221 atggcaatgc agagcctgac gttgaatacc atcttccaga ctaccaccat acaaatcatc
     8281 tcccagcaaa ggaaaaccga tatgagaaaa atggactcgg atttgatggg ttcgaccagt
     8341 gtgcaggtga atatagacca agtgaatatt tccataagaa gctacaatct tgtatgaagt
     8401 atgggcatac tttccgcctt tagccactcg tctggtaata atggaatctt catcacgcgc
     8461 aatcggagca ataatttccc cttctggctc caaatgtcca tctcccttaa ccaaagcaaa
     8521 gtagcgtttc tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat gggcataacc
     8581 gtgcttggca aagagcatca agccagaagt gtccctatct agtctggtaa caatgtgaac
     8641 ctgctgattt tcataatttt gcttgacata gtaacccttg ataaaattgg caatggtatt
     8701 agagtgattg acactaggaa tagaagccac tccatagggt ttattcaaga ctagaaagtg
     8761 gtcatcctca tagagaatat ctaatggatg ctcaatagcc tccaaggttt caaagccttc
     8821 ctcagcggga atgtaaatgg taacgtagtc tccaacgtcc aatagatacg ttgcattttg
     8881 cggttgatta ttgaccagaa tagctccacc tcgaaactta atcttagcca gcaatccctt
     8941 agaaacctcg tgctttttta aaaaggtctt aaccttgaca tgttcatctg cgataaattc
     9001 aaacctcatt catccacctc accgataaag gcatccttaa cacggttcca gaaactggta
     9061 tggctaggag tcgcgacaaa gtgaatctta tgatggtcga tttgatactc aatacgctca
     9121 atattacgga aagaataaac gctattgtca accgaaatag tatgataatc gtttcttgtt
     9181 ggaataagtt caatcttatc cttcttaggc acaataatgg aagagcccag tgttcgataa
     9241 acacgattat taaggctggc aatttccgtt aattgcaaag cttcaatggt agggtgtaaa
     9301 acagcaccgc caagagactt gttataggca gtactaccag tcggtgtcga aactgttagc
     9361 ccgtctccac gaaaacgttc aaagggaaca ccatttatta caatatctgc caccatggtt
     9421 cgatcagacc tgcggatgct ggcttcgttg agtgctctga aaatcttaac ttcaccattt
     9481 tcaagaaaga ccttcacatt cagaacaggg taagaaaccc ttgccccagt atctagctgc
     9541 aaattagtca ctagcttgtc caactcaaaa tcacgataat ctgtatagaa gcccaaatgt
     9601 ccagtatgaa gaccgataaa gcggaccttg tcaagctgat tttcgtactt atgaaaggcc
     9661 gacaagagca taccatcccc gccaatggaa atgacaatat ccggattggt atcattgagt
     9721 ataaactgat ttctcttcaa acgatctcgc aattcataca aaaccctttg actctgcggt
     9781 tttctattgg ctatcagatc aattcgttta cctgtattct tcatctgtat cgtcactgtt
     9841 tcctacaccg tcatttaatt ttctactcaa aggatcaaaa agtgcctggg cttcttggat
     9901 atcatcacga atttcaccca tttcttcatc caactgatgg gcgattctag ctgtaatttc
     9961 cagtcgcttc ttaatctcat ctgggaaatc cccttggtac ttgtagttga gagaatgttc
    10021 tatcgttgcc cagaaattca tagccaaagt acgaatttga atttctgcca aaatagtctt
    10081 agctccattg atggtatcaa ccgtatattc tactaccaca tgataggaac gatagcctga
    10141 tgcttttcta tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct gacgcttgtg
    10201 caaaatatcc actacttcct tgacgtcatc tacaaactga accatcacac gtaagccagc
    10261 aatatcctgc aaatcgtgtt ccaaggtcgc ataagtaatg ccacgacgag ccattttttc
    10321 tttgatgctc tcaattggct tgactcgacc ggtcacaaac tcaattggag aatgcttatt
    10381 ttgcttacga tattgcttac gaataccacg aagtttaatc tttaactcac caacagcttg
    10441 aatgtaagga tctagaaatt cttcccattc taaggtcata tattctccct tgttctcata
    10501 ttatccgtca aaaatatctt tgattttttc tccagattca tatacaataa atacaatgct
    10561 tattatacca taaatccgct ttcaacgata aaaaaaggta agaaaaatga aacatttaga
    10621 aattgaattg aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag accagttcac
    10681 aggtgtcact cctgttcttc aaacaaatta ctacatagac acgcctgatt ttgaactgcg
    10741 agaaaagaaa gtcgctatgc gcattcgaac ctttgaagac tgggctgagt tgacactcaa
    10801 agtcccgcag agtgttggaa acatggaata caaccaaaaa ttgcaactaa aagatgctga
    10861 ggactatctg agtaaggaag aacttcctca aggactagta ctggatgaat tggcgaaaca
    10921 tggtatccaa agtaagaact ggcaggttct tggttgtcta acaacgcttc gctatgaaat
    10981 gaaaacagct attggtctca tggcactgga tcagagccga tactttgata tgacagatta
    11041 cgaattggag cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc gacaattttt
    11101 agagaaaaat cagatttcct accaaaaagc tccttcaaaa ttggttcgat ttgtcaaaag
    11161 tatgaaaaat agctgaaata atctccattt tttggtaaaa tagaaaagat aaaaatacac
    11221 aaaccctagt tatatgtaag gtaaatataa ctaggattta taaagtttac agaggacggt
    11281 ctataatgtc agatagaaaa aacatgaaac ttttcgcact caactctaac caagagattg
    11341 cacagaaaat tgcccaagct gttggtgtcc cacttggaaa actatcatca cgtcaatttt
    11401 cagacggaga aatccaagta aatatcgaag aaagtgtccg tggttatgat gtttacatca
    11461 tccaatcaac aagtttccct gtcaacaacc acctaatgga actgttaatc atggtcgatg
    11521 cttgtgtgcg tgcaagtgcc cacagtatca acgttgtcct tccatatttt ggctatgcac
    11581 gtcaagaccg cattgcttgt cctcgtgagc cacttacagc aaaactagtt gccaatatgc
    11641 tggttaaggc tggagttgat cgtatcctga ctcttgattt gcatgccgtt caggttcaag
    11701 gtttctttga tattccagtg gataatcttt tcactgttcc cctattcgca aaacattact
    11761 gcgataaagg attgcttggt tcagatgttg ttgtcgttag ccctaaaaat tcaggtgtca
    11821 aacgtgcgcg tagcctggct gaatatcttg atgctcctat cgccattatc gactaccctc
    11881 aagacgatgc aactcgtaac gaaggttata ttattggtga tgttgaaggt aagaaagcta
    11941 tcttgattga tgatatttta aatacaggac gtaccttctc tgaagcttct aaaatcgttg
    12001 aacgtgaagg agctacagaa atttatgctg tttctagcca cggtctcttc gtcgagggag
    12061 ctgctgagct tcttgacaat actaatatta aagaaattct tgtgactgat tcagtagcaa
    12121 caaaagaaaa aactcctaaa aatgtatgct acatcactgc tagtgagtta attggtgatg
    12181 ctatcgtccg tattcacgaa agaaaaccag tcagcccact ctttgcctac aataaaaaga
    12241 aataaggtga ttctttgatt tatttggaca atgctgcaac gactcctatg tcagcagttg
    12301 ctatttcagc tatgaccaag gttatgcaag aaacccacgg aaatccttct agtattcatg
    12361 gtcatggtcg tcaagctggc aaactcttgc gagaagcccg tcaggaacta gcccagttac
    12421 taaggacaaa acctcaacat atctttttca cttctggtgg gactgaaggc aataatacta
    12481 ccatcattgg ctactgtctt cgtcaccaag aacaaggaaa acatatcatc acaactgcca
    12541 tcgagcacca tgctgtcctt gaaacaattg attacttggt tcaacacttt gggtttgaag
    12601 caaccattat ccagccagaa aatcaagaaa tcacagccca gcaaattcaa aaggctttac
    12661 gtgacgatac gattttggtt tctaccatgt ttgccaataa tgagacagga aacctactgc
    12721 ccatcgctga aattggccaa atactcaagc aacaccctgc tgcctatcat gttgatgcag
    12781 ttcaggctat tggtaaaatc ccaattcatt cagaagaatt gggcattgat tttctcactg
    12841 cttctgccca caaattccat ggtcctaagg gaatcggttt tctctacgca tctagcatgg
    12901 actttgattc ctatctacat ggcggagacc aggaacagaa aaaacgtgca ggaactgaaa
    12961 atctgcctgc catcgtaggc atggttgcag ccctaaaaga agacctagaa aaacaagaag
    13021 aacattttca acatgtacaa aatctagaaa ctgcctttct ggcagagctg gagggcattc
    13081 agtattacct gaatagagga aaacatcatc tcccttatgt tctcaatatt ggatttcctg
    13141 gtcagaaaaa tgacctctta ctccttcggc tagatttagc tggaatttca atctctactg
    13201 gctcagcctg tactgcaggc gttgtccaat ccagccatgt tcttgaagcc atgtatggcg
    13261 caaattcaga acgcttgaag gaatcccttc gcatcagttt gtcgccacaa aataccgttg
    13321 aagacctaca aaccctcgca aaaaccttaa aagaaattat cggaggttag ccatatggca
    13381 tttgaaaaaa tcattcagtt aaaaaattgt cgttacgatt acactcttag cccttctgtt
    13441 aaaaaattca ccctcaaaga taacaccttt tttgaaacta aggttggtaa ctatgaactg
    13501 actcgccttt tggaaaaagt gccaaacagc ggtgaaggct tccaactcaa aatcatcatt
    13561 aacaaggaac ttacaggggc taaaatcaat atcactgaca agtttggcct tcgtctagtt
    13621 gatattttca aatcagaaga ccaccatatt catcaggaaa aattctactt cctcatggat
    13681 agcttggtag aacgtggtgt ctttacaaaa tcggaaagat agagccaaaa tgtttgaact
    13741 gacctataag gactgctatc atgtagagcg tactctcaag tatgaggatc atgaggctct
    13801 catgttgact ttgtcaggat gtgtaacctt accagataca ctttatgtga cttctctgac
    13861 ttttaggggc caaaaagttt atcagggtct ggtcggagac ctctaccgtt ttctatctca
    13921 tgcagatttt ttacatcaaa actaagattt ttcttagttt tttcttattt ttgttgattt
    13981 tttcacaatg tttctataaa atagaagaat agaaaggttg tgattttgtg aaagataaac
    14041 agtttgctat tccaaaagct acagcaaaaa gactctctct ctactatcga atttttaaga
    14101 gatttcatgc agaaaagatt gaacgtgcca actctaagca aattgcagag gccattggga
    14161 ttgattcagc gaccgtacgt cgtgattttt cctattttgg tgaacttggt cgtcgtggtt
    14221 ttggctatga tgtcaaaaaa ctaatgacat tttttgccga tttgctcaat gacaactcta
    14281 ttaccaatgt catgctggtt ggtattggaa atatgggcca tgcccttctc cactaccgct
    14341 tccacgaacg taacaagatg aagattatca tggcctttga cctagacgac catcctgaag
    14401 tcggtaccca aactcctgac gggattccca tttacgggat ttctcagatc aaggataaaa
    14461 tcaaggatgc tgatgtgaag actgctatcc taactgttcc cagcgtcaag tcacaagagg
    14521 ttgctaatct cttggttgat gctggtgtga aaggaattct cagtttttca ccagtccatc
    14581 tgcatttacc aaaagacgtg gtcgttcagt atgtcgattt gacaagtgaa ctccaaaccc
    14641 tcctctactt catgcgaaaa gaggattaga aagcgaaaat cattttatga aaaaaccagt
    14701 tattgggatt acaggaaacg aaaaaactca tccagatgat gacatcatga tgagctacgc
    14761 agcaaaaggc tttgttgaag gcgttaaaga tgctggaggg attcccatca tcctaccgat
    14821 tggtgatcaa gaaatggcct gccactatat cagtttgatt gacaagctca tcttgacagg
    14881 tgggcaaaat gtcgatccaa aattctatgg cgaacccaaa accattgata gcgatgatta
    14941 tcaccttcaa agagatatct tcgaactggc cctcatcaag gaagctatta aacagaaaaa
    15001 gcccattttc tctgtctgcc gtggtaccca actctttaac gttgccatgg gtggaacttt
    15061 gtaccaagat atcgaagacc attggcagga ttcttctgtt gagtacacaa ctcaacgctt
    15121 ggtaacagaa ccagataccg ttctccaaga aatctatgga gaaatctctc atatcaactc
    15181 cttccaccac cagagcatca aggacttagc accaaattta aaagttgtgg ctcatgatcc
    15241 taaagatggt atcattgagg ctgtcatgag tacggatgat gtcgcctttc tcggtgtcca
    15301 atggcatcca gaacttcttt ttgaaaatcg tcccaaagat aagaaactct ttgactatgt
    15361 cgttaatgaa ctttagatta aatctgtctt ttcacgataa ctaaagtaat tagaatgaga
    15421 gacaatcaaa tggtccaaga gaacaatccc catcagttcg caggcttctt taacaagttt
    15481 agtgacatga tcatcatttt ggctaggcgc taccgctcct gaaggatgat tgtggaccaa
    15541 gataagagaa gtcgccatat gcttgattgc atagtgaaga atctctcgcg gttcagcgat
    15601 actacgagtt acagaaccga taaaaatggt ctgctgatgg atgatttgat tttgagtatt
    15661 gagatagagt gccaccaggt gctcttgttt tttatcccct aattcctgct gcatcttctt
    15721 ggccaacttt tgactgctga gaatactttc catttcaaga gtctcgtgtt tgtgaatacg
    15781 atgccccagt tcaatcatag cttgtaattc tatggcctta acacgcccaa taccagacaa
    15841 actctgcaat tcctgcaggg tcattttttt caaatccgtt aggcttgaaa gattgtttaa
    15901 gactttttgg gcaatttcaa aaacgctagc ttgacgtgtt cctgtcctga gtaaaatagc
    15961 tagcaactct tggttactaa gcgcttcaac tccttccttg gccagccttt ctcttggtaa
    16021 tagtgaatct tcttggaatg aaatactgta cataaaaatc ctcctcactt tattattcgt
    16081 gagaaggatg gaaaattaga tttttttctc aattggagcc acactggcta aaagtttttt
    16141 caaacctact tctgggaaat tgattttcaa ttcctgccta gcaccgctac ctgaaacttc
    16201 cagaacggtt ccctctcccc atttcttgtg gagagcaata tcaccaatgg accaatttgc
    16261 ctcgctagat gctggttttg cgccagctgt aaattgacca aatggaagac cgcttgactg
    16321 gattgatttt ggggcagcac cgcgtttacg gtcttgaaga gcctgagcca aactcatacc
    16381 ttgaccaaag gaaatactac cactgctata tgatgcctta aagcttgtat ttgcaggacg
    16441 agccagacct tgatactcaa gcaagtctga actgatttcg ttaataaaac gagtcggacg
    16501 gttataattg gtacgaccaa aaagcaagcg tgagttggca ttggtcagat agagaatttt
    16561 ctctgcacgc gtgataccta cataggctag acggcgctct tcttctaatt catctggatc
    16621 ttcagtcgca cgactaagtg gaaagacatt ttcttccatc ccaatcaaaa agacaactgg
    16681 aaattcgaga cctttggcag catgcagggt catcaaggtc acttctgatg tctcctgact
    16741 acctgaatct gtgtcggcaa tcaaagccaa gtcatttaag aaacgactca gtttgtccag
    16801 accagtttcc tcttttgtca catcagtggt gtcatcaaag ttcttcgtaa cagaaagaaa
    16861 ctcttcgata ttttcaaccc gtgccttgct ttctagagtc gcttgggcgt taagaatatc
    16921 gatataacct gttttttcta ggacggactc aaccaactct gtaatgctta agtggtctag
    16981 ctgctcccgc aaatcaagca tcatattggc aaaatcccag atagattggg ctgccttacc
    17041 cttgatacca gacaacataa tattagcaga agcatccagc atagacatat tttgcaaatt
    17101 tgcaaaatca cggattttct caactgtacc tagaccaatt ccacgtttag gctcgttgat
    17161 aatacgctca aaactaatgt tgtcactcaa attagcaata aggttgagat aagcaataat
    17221 atcgcgaatt tccttacggc tgtagaattt cgttccgcca accatggtat aaggaatgtt
    17281 agacttgagc agggcttcct caattgtacg ggactgggca ttagtccgat agagaactgc
    17341 aaaatcctta tgaaggaagt tttgactgcg actaagttca tcgatggttc tggctacaaa
    17401 tacagcctca tccagctcat catcagcacg atagtaaacg atttgctccc catcagcgtt
    17461 ttgagtccag agatttttag gacggcgatt tttattattt ttaataacct cgttggccgc
    17521 ttggagaatg gttttggttg agcggtaatt ttcctccaac aaaacaacct tagctttggg
    17581 gtaatccttt tcaaagtcca agatattctg catatcagca ccacgccaac cgtagataga
    17641 ctggtccgca tccccaacca cacagatatt tttaaaacgg gaagccaaga gtttgaccaa
    17701 ttggtactga gcgtggttgg tatcttggta ctcatcaacg tggatgtatt ggaatttttg
    17761 ctggtagtag gtcaaaacat caggattttg atcaaagaga cgcaaggtca gcataatcaa
    17821 atcatcaaag tcaacggatt cagactgacg aagttctttt tgataggctg tataacactg
    17881 ggccacaatt tgcgtataca tatcgccagc ttgggcagca taagcaacat catcaatcaa
    17941 atcattctta gcattggaaa tggtccccaa aatagttcgt tcattccatt ttttaggatc
    18001 caagttcaac tgtttgagaa tacgtttcat gagcgttcgc tgttcaccag gatccacaat
    18061 tgtaaaatta cgattgtagc caatatggtc cgcatcgcga cgcaaaatac gcacacacat
    18121 ggagtggaag gtcgcaatca gacagtcctg agtagctgga ttgaggctat aagcacgctc
    18181 tttcatctca cgcgcagcct tgttggtaaa ggtaatggcc aagatattcc aaggattgac
    18241 cagcttttca tcaatcaaat aagcgatacg gtgggttaaa acacgagtct ttccagaacc
    18301 agctcctgcc atgattagca agggaccttc tgtcgtttgc accgcctcag cctgacggtc
    18361 attcattcca tttaataatg cgttcatctt ctcttcctta ctcttgaagt caatatttct
    18421 attatatcag aaatcaggga aaatagaaac tttacgggga gtagcaaaat atagtggatt
    18481 gaaactagaa tactacactg tgggtttcta aaacactcga cttttcaccc aattttttca
    18541 taaactagct caatagactt cctgcaaaac tagaatccta gttcatgatt gataatgcca
    18601 gcaatcaaat tcattcgtaa tccgaagcgt ttacgatgat ttcgatagat tgttgaaaac
    18661 attttaaacg tttttacttt ggcaaagacg ttctcgacct tgcttctctc cttagatagc
    18721 gcatggttac aggctttatc ttcagctatt agcggcttga gtttgctgga tttacgtgga
    18781 gtttgtgctt gaggatatat cttcatgggc ccttgataac cactgtcagc caagatttta
    18841 ccagcttgtc cgatatttct gcgactcatt ttgaacaact tcatatcatg acaatagttc
    18901 acagtgatat ccaaagaaac aattctccct tgacttgtga caatcgcctg agccttcata
    18961 gcgtgatatt tctttttact tccgtcacat caatcattac cgtgtcctca gaactgagag
    19021 gagttcttga aatcgtaaca ccactttgaa caagagttac ttcaacccat tagctccgac
    19081 ggataaagtt gctttcgtgg ataccaaaaa cagccgcaat ttcttcataa gttcgatatt
    19141 ctaggc
//
LOCUS       DAVHSL010000044        18115 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000044 DAVHSL010000000
VERSION     DAVHSL010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.045"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            364..1410
                     /gene="pheS"
                     /locus_tag="VVR39_001581"
     CDS             364..1410
                     /gene="pheS"
                     /locus_tag="VVR39_001581"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU6031022.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1410..1919
                     /locus_tag="VVR39_001582"
     CDS             1410..1919
                     /locus_tag="VVR39_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031023.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1996..4401
                     /locus_tag="VVR39_001583"
     CDS             1996..4401
                     /locus_tag="VVR39_001583"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU6031024.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFARLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPAAPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4469..5470)
                     /locus_tag="VVR39_001584"
     CDS             complement(4469..5470)
                     /locus_tag="VVR39_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6031025.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYNKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATKIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFKRGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5626..6071
                     /locus_tag="VVR39_001585"
                     /pseudo
     CDS             5626..6071
                     /locus_tag="VVR39_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6197..6463
                     /locus_tag="VVR39_001586"
     CDS             6197..6463
                     /locus_tag="VVR39_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031026.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            6723..8972
                     /gene="metE"
                     /locus_tag="VVR39_001587"
     CDS             6723..8972
                     /gene="metE"
                     /locus_tag="VVR39_001587"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU6031027.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEVAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9036..9902
                     /gene="metF"
                     /locus_tag="VVR39_001588"
     CDS             9036..9902
                     /gene="metF"
                     /locus_tag="VVR39_001588"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU6031028.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10461..12674
                     /gene="pnp"
                     /locus_tag="VVR39_001589"
     CDS             10461..12674
                     /gene="pnp"
                     /locus_tag="VVR39_001589"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU6031029.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12690..13307
                     /gene="cysE"
                     /locus_tag="VVR39_001590"
     CDS             12690..13307
                     /gene="cysE"
                     /locus_tag="VVR39_001590"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU6031030.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13319..14203
                     /locus_tag="VVR39_001591"
     CDS             13319..14203
                     /locus_tag="VVR39_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031031.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14290..15633
                     /locus_tag="VVR39_001592"
     CDS             14290..15633
                     /locus_tag="VVR39_001592"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU6031032.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15626..16012
                     /locus_tag="VVR39_001593"
     CDS             15626..16012
                     /locus_tag="VVR39_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU6031033.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16016..16900
                     /locus_tag="VVR39_001594"
     CDS             16016..16900
                     /locus_tag="VVR39_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU6031034.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGVQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17037..17636
                     /locus_tag="VVR39_001595"
     CDS             17037..17636
                     /locus_tag="VVR39_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031035.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            17779..17949
                     /locus_tag="VVR39_001596"
                     /pseudo
     CDS             17779..17949
                     /locus_tag="VVR39_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5459 a         3486 c         4112 g         5058 t
ORIGIN      
        1 gaaattaatt ttactttccc aatcgatttg ttctcatctt atttcaatcc gctataaagt
       61 tagataagaa taagctaaca agcagaagta agataggtct tgcaagaatg gtaaaaatct
      121 gataaactaa gtagtaattg aataggaatc tgaaagacta gtagcccaag ggaagtatat
      181 cagggaggag agccgtgact gcaagctctc tatatgaaag ctgggtgaat tcacttgcgc
      241 atggatttag aaatgaaggt ctgacttgtc agatgaaaac ggatggtacc gcgtgtcaac
      301 gctccgagtg gagtttttgg catgtggttt tctttttatc tacgagagac tgatggagga
      361 aatatgtcaa ctattgaaga acaattaaaa gcgcttcgcg aagaaacgct ggctagcttg
      421 aagcagatta ctgctggaaa tgaaaaagag atgcaagatt tgcgtgtctc tgtccttggt
      481 aaaaagggtt cgctcactga aatcctcaaa gggatgaaag atgtttctgc tgagatgcgt
      541 ccaatcatcg ggaaacacgt caatgaagct cgtgatgtct tgacagctgc ttttgaagaa
      601 acagctaagc tcttggaaga aaagaaagtc gcggctcaac tggctagcga gagtatcgat
      661 gtgacgcttc caggtcgtcc agttgcgact ggtcaccgtc acgttttgac acaaaccagt
      721 gaagaaatcg aagatatctt catcggtatg ggttatcaag tcgtggatgg ttttgaagtg
      781 gagcaagact actataactt tgaacgtatg aaccttccaa aagaccaccc agctcgtgat
      841 atgcaggata ctttctatat cactgaagaa atcttgctcc gtacccacac gtctccagtt
      901 caggcgcgtg ctatggatgc ccatgatttt tctaaaggtc ctttgaagat gatctcgcca
      961 gggcgtgtct tccgtcgcga tacggacgat gcgacccaca gtcaccaatt ccaccaaatc
     1021 gaaggcttgg tagttgggaa aaatatctct atggctgatc ttcaaggaac gcttcagttg
     1081 attgtccaaa aaatgtttgg tgaagagcgt caaattcgtt tgcgtccatc ttacttccca
     1141 ttcacagagc catctgttga ggtggatgtt tcttgcttca agtgtggtgg agaaggctgt
     1201 aatgtatgta agaaaacagg ttggatcgaa attatggggg ccggtatggt tcacccacgt
     1261 gtccttgaaa tgagtggtat cgatgcgact gtatactctg gctttgcctt tggtcttgga
     1321 caagagcgtg tagctatgct ccgttatgga atcaacgata tccgtggatt ctaccaagga
     1381 gatgtccgct tctcagaaca gtttaaataa tgattagaaa agtagaaatg gcagatgttg
     1441 aggtgttggc taaaattgcc aaacaaacct ttcgtgaaac ctttgcgtat gataatacgg
     1501 aagagcagtt acaggaatac tttgaagagg cttatagtct aaaaactttg tcaactgagt
     1561 tgggaaatcc tgactctgaa acctatttca ttatgcatga ggaggagata gctggttttc
     1621 tcaaagtcaa ctggggaagt gctcaaactg agagagaatt agaggacgct tttgaaattc
     1681 aacgcctcta tgtgctacaa aaattccaag gatttggact aggtaagcaa ctgtttgaat
     1741 tcgcacttga acttgctaca aaaaatagtt tttcttgggc ttggctaggt gtttgggagc
     1801 ataatacaaa agctcaagcg ttttataatc gatatggttt tgaaaaattt agccaacatc
     1861 attttatggt tggtcaaaaa gtagatacgg attggttact gagaaagaaa ttaaggtaag
     1921 aagaggattc ttctattgaa atgataggaa aggaaaagaa ccagtgtggc aatggtcatt
     1981 ctggagaact aaattatgct tgtatcttat aaatggttaa aagaattggt ggacattgat
     2041 gtgccatcac aagagttggc tgaaaaaatg tcaactacag ggatcgaggt agagggtgtc
     2101 gaatcaccag ctgctggtct ctcaaaaatt gtcgtcggtg aggtcttgtc ttgcgaagat
     2161 gtgccagaga ctcacctcca tgtttgtcag gttaacgttg gcgaagaaga agagcgtcag
     2221 atcgtttgtg gtgccccaaa tgtgcgtgct gggatcaagg tcatggtggc tcttccagga
     2281 gctcgtatcg ctgataacta caaaatcaaa aaaggaaaaa tccgtggttt ggagtcactt
     2341 ggaatgatct gttcacttgg tgaattggga atttctgact cagttgtgcc taaggaattc
     2401 gcagatggca tccaaatctt gccagaaaat gccgtgccag gtgaggaagt cttttcttac
     2461 ctagacttgg atgatgaaat catcgaactt tccatcacac caaaccgtgc agatgccctt
     2521 tctatgtgtg gagtggctca cgaagtggca gccatctatg acaaggcagt caactttaaa
     2581 gaatttactc taacagaaac taatgaatct gcggcagatg ccctttctgt cagcattggg
     2641 acagacaagg cgccttacta tgcagctcgt atcttggaca atgtgactat cgcaccaagt
     2701 ccacaatggt tgcaaaacct tctcatgaac gaaggcatcc gtcccatcaa taacgttgta
     2761 gacgtgacaa actacatcct gctctacttt ggtcaaccta tgcatgcttt tgacttggac
     2821 acatttgaag ggactgacat ccgtgtgcgt gaagcgcgtg ctggtgaaaa attggtgacc
     2881 ttggacggtg aagaacgtga cttggacgtg aatgacctag tcatcactgt cgcagacaag
     2941 ccagtagccc ttgcaggtgt catgggtggt caagcaacag aaatctctga aaaatctagt
     3001 cgtgttgtcc ttgaagctgc tgttttcaat ggcaaatcta tccgtaagac aagtggtcgc
     3061 ctgaaccttc gttctgagtc atcttctcgc tttgaaaaag gaattaatgt ggcaacagtt
     3121 aatgaagccc ttgatgcggc agctagcctg attgcggaac ttgcaggtgc gacggtgcgt
     3181 aagggcatcg tttcagcggg tgagcttgat acttcagatg tagaagtttc ttcaaccctt
     3241 gctgatgtta accgtgtcct cggaactgag ctgtcttatg ctgatgtaga agacgtcttc
     3301 cgtcgtcttg gctttggtct ttctggaaat gcagacagct ttacagtcag agtcccacgt
     3361 cgtcgttggg atatcacaat cgaagctgac ctctttgaag aaattgctcg tatctatggt
     3421 tatgaccgct tgccaactag tctaccaaaa gacgatggta cagcaggtga attgacagcc
     3481 acacaaaaac tccgccgtca agttcgtact attgctgaag gagcaggttt gacagaaatc
     3541 atcacctata ctctaacaac tcctgaaaaa gcagttgagt ttacggctca accaagtaac
     3601 cttacggaac tcatgtggcc aatgactgtg gatcgttcag tcctccgtca aaatatgatt
     3661 tcaggtatcc ttgataccgt tgcctacaac gtggctcgta agaataaaaa cttggccctt
     3721 tacgagattg gaaaagtctt tgaacaaaca ggtaatccaa aagaagaact tccaaatgag
     3781 atcaacagct ttgcctttgc cttgacaggc ttggttgctg aaaaagattt ccaaacagca
     3841 gcagttccag ttgatttctt ctatgctaag ggaatccttg aagccctatt tgctcgtttg
     3901 ggactccaag taacctatac agcaacatct gaaatcgcta gccttcatcc aggtcgtaca
     3961 gccgtgattt cactcggtga ccaagttctt ggtttccttg gccaagtgca tccagtcact
     4021 gctaaggctt atgatattcc agaaacgtat gtagctgagc ttaacctttc agctatcgaa
     4081 gctgcgcttc agccagcggc tccatttgta gaaatcacca aattcccggc agtcagccgt
     4141 gacgttgccc ttctcctcaa ggcagaagtg actcatcaag aagttgtaga tgctatccaa
     4201 gctgccggcg tgaaacgttt gacagatatc aaactctttg acgtcttctc aggtgagaaa
     4261 ttgggacttg gtatgaagtc catggcttat agcttgacct tccaaaatcc agaagatagc
     4321 ttaacggacg aagaagtcgc acgctatatg gaaaaaatcc aagcttctct cgaagaaaaa
     4381 gtcaatgcag aagtgcgtta aacgatagta tgatacaaat cacccctcta gtttatgaac
     4441 actagagggg tgattttata taaaataatt aaaatgtgat ttctgtaaaa atacatctat
     4501 gatcagagtt ttgaaaactt acaatgtcta aatctttaac atagtagtgg tttttaggca
     4561 ataaaatatg atctattgtt gcattaaaaa gttttggact ttggctattc caagttcctc
     4621 ttttaaaggg tggaagtgca ttcaatgcgt ccctatgaga gcttattttt gcaagtgctc
     4681 catgacgcat agttgcatta aaatcacctg caataatagc ctttggatat tttgaagcca
     4741 attgattatg aatgatgttt aagtcttgct tccagatttc cattaaacct ggcagaggag
     4801 gagcagtatg caaggcaatg atatctggta tattttgttt tctcgaatgt aatacaattg
     4861 tcccgaaccg tgttgtatga aaagttttag cttctgtata gaaaccataa cttttcttga
     4921 caatcacagt cacaggagct attccactat tggtaggtgg agaagtgaaa atatcatagt
     4981 tggccataga aagtccaact tgatgaaaca atagtttgat tctctggttt tcttgctcac
     5041 ctctgatctt ggtagctagt tcagggaata tagccatatc ggcatcaaaa tggctaaaaa
     5101 ttcgctcaat atgttgtgct tctatttgat tagcgacgtt ccaagttact aattttaagg
     5161 ttttagtctt atttgatgca gaagaaaggg ttttatctgt tccgaataat agtaatatga
     5221 gcgatagtaa gagcaaaatg ccagagtaaa accgtatttg tttattttta ttgtaaaaag
     5281 atagggaaaa aaatacgaaa cttaaaatag aagccatagt tgcagtagct aaggggaagg
     5341 cataaatctg tgccaagata ggtctggtag atagccaaat attaagatta gaagatggaa
     5401 aaaaagaata agttatgata gggataacaa agagaatgac cgaaagggca gagagaaatg
     5461 ttttaatcat tgtgtgagta cctcaatttg caatggttgc tcggagctaa tgtgactttg
     5521 tgactttact tgattgatat tctttttctt gtcttcctca tagattaagt acaacccaag
     5581 taaaaaaagt ccaatttaag attgaaatga ttaaaaggca cagagatgca agacaattat
     5641 actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag atggaaaaaa
     5701 gaaggaaaat caaatagaga agttgcctct ctacttggaa aagctcctca aactatccac
     5761 actgaaatca agcgtgggac agtccgaaaa tgtcttggaa aagggcgctt caaagaggtt
     5821 tattctgccg actacgctca acagtgttat gaaaacaatc gcaagcgctc ggtcaagaaa
     5881 tcaagcttga ccaaggaact aaaggaaaag attccactat acataaccaa aaattttcgc
     5941 ctgaaatgat ggttatggct aaaggggtta acgtgggaat ttcaaccatt tactattgga
     6001 ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttatcctaga aaaggaaaat
     6061 cgcttaagaa ataggctagc accaacttta aacccgctgg tcaatctatc gaatcataat
     6121 tcgctcattt ttttaaaaat acatagacgt aaaagaaaga gggttaagtg atgaagaata
     6181 gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg aggaaatcct
     6241 tgaaagtgat atgcgagtag ctatcatgag cgagttgatt gaagccagaa ataagcaagg
     6301 aatcagtcag aaaaagctag aggaactcag tggagtgagt cagcctgtta tagctaggat
     6361 ggagacaggt aagactagtc cacagttgga cacagtctta aaagtcctag ctagtctagg
     6421 aaagatacta gcagtcgtcc gacttgaaca ggggaaaagt tgactagaat cagttatagt
     6481 cttttctaat aacaagccat agtcacttat aagaattact aataacgctt ttgagcattc
     6541 taactaaaat acagctaaaa acaagttata aaagggattt gaggcatgtg tctcaagtct
     6601 ttttcttttg tctaaaacag aggtatagtt tcaaactata tcaaagccta attttttaca
     6661 attatacaga tgatttcttt tctgttaaga tagtttcaac aacaaatttt ggaggacaca
     6721 tcatgtcaac tacaatcatc ggtttccctc gtttgggcga attccgtgaa ttaaaattta
     6781 caactgaaaa atactttaga aaagaaatct cagaagaaga acttttagca gcagcaaaag
     6841 acttgcgtgc taaacactgg aacattgtca aagaaaaagg catcactgaa attccatcaa
     6901 atgacttttc tcactatgat aacttcctag atgcggcttt ccttttcaac gtggtgcctg
     6961 catccgttca aaacttggac ttgtctgacc ttgagcgcta cttcgctttg ggacgtggtt
     7021 accagggaga aaaaggggac gttcgcgccc ttccaatgaa gaaatggttc aacactaact
     7081 accactacat cgttcctaaa tttgaaaaag acactcaagt aaaattggct ggtcacaaga
     7141 ttttcgatga gttccaagaa gcaaaagaac ttggattgaa cactcgtcct gttcttgtag
     7201 gtccattcac tttccttcaa ttgtcagact ttgaagaagg cgtgaaagca gacgacttcg
     7261 tagatagctt agtggctgct taccaagaag tttttgctaa attggctgaa cttggtgcga
     7321 ctcgcatcca attggatgaa gcggctcttg taaaagactt gacagctgaa gaaaaagctc
     7381 tcttcttgaa cctttacaac aaactcttgg ctgacaaaaa aggtcttgaa gtcttgcttc
     7441 aaacttattt cggtgatgtt cgtgacgtat acgctgacct tgtaaacttg ccagtagatg
     7501 ctatcggtct tgactttgtt gaaggtaaga aaactcttga actcgttaaa ggtggcttcc
     7561 cagctgacaa gactctctat gtaggtattg tcaatggtaa aaacatctgg cgcaacaact
     7621 acgaaaagag cttggctgtt cttgagcaaa tcccagctga aaacatcgtt ttgacaagct
     7681 cttgctcact tcttcatgtg ccatttacaa ctgctaatga agaatttgaa ccagcactct
     7741 tgaaccactt tgcctttgca gttgaaaaat tggatgaaat ccgtgacttg gatgctatcc
     7801 gcaatggtca aggttcagaa gctcttgcag ccaacaaaga actctttgcg actgagcgtg
     7861 ttggtgaaaa tgctgaactt cgtgcgcgta tcgctggctt gacagacgca gactacactc
     7921 gtttgccagc ctttgcagaa cgtgaagcta tccaagaaga agctttcaaa cttccagctc
     7981 ttccaacaac aacgattggt tcattccctc aaacaaaaga agttcgtgcc aaacgtttgg
     8041 cttaccgtaa aggtgaattg tctcaaaaag agtacgacgc tttccttgct gaaacgattg
     8101 acgaatggat caagtggcaa gaagatattg actttgatgt ccttgttcac ggtgaatttg
     8161 agcgtaatga catggttgag tacttcggtc aaaacttgtc aggttacctc ttctctaaaa
     8221 atggttgggt acagtcatac ggtatgcgtg gggtgaaacc accaatcatc tggggtgatg
     8281 tcactcgtct taaccctatc actgttaaat ggtctagcta tgcacaaagt cgtacaaaca
     8341 aacctgttaa aggtatgttg actggacctg ttaccattct taactggtca ttcccacgtg
     8401 aagacatctc tatcaaggat tcaactcttc aaatcgccct tgctatcaag gatgaagtac
     8461 ttgaccttga agttgctggt gtgaagatca tccaaatcga tgaggctgct cttcgtgaaa
     8521 aattgccact ccgtcgtagc gactggtacg aagactacct tgactgggca attcctgcct
     8581 tccgcttggt acactcaaca gtagcgccag acacacaaat ccacactcac atgtgttact
     8641 cagaatttac agatatcatc ccagctatcg ataacatgga tgcagacgtt atttcctttg
     8701 aagctagccg ttcaaacctt gaaatcttgg acgaactcaa agcgaaaaac ttccaaacag
     8761 aagtgggacc tggggtttac gatatccact cacctcgtgt accaaatgaa ggcgaaatcg
     8821 acaacacaat cgaagccatc cttgctaaag tgccaagcaa gaaagtttgg atcaaccctg
     8881 actgtggttt gaaaacacgt ggtatcccag aaacaaaaga aagcttgatc cgccttgttg
     8941 aagcagctaa agctgcgcgt gagaaattgt aagattggat ttctctccat acagtggttg
     9001 ttcaaaaaga aatcaactag aaaaggttat tacatatgtc acgccaaaca ccgtcactct
     9061 catttgaagt gttccctcca aacccagccg tgggtaatgg taacattatt tcagccttgc
     9121 aggatatgca ggagttggct ccccatttta tcagtgtaac tgccagcaat aataaattta
     9181 atatcaagga aacgacggtt cgtttggctg actttatcca aaatgatttg gcgattccga
     9241 ccattgccca cttgccagct atttatctaa ctaaggacaa ggttgctgaa actattgctg
     9301 acttggacaa agttggggtg cagaaaatct tggctcttcg tggggatatt attccagacg
     9361 tggaaccaca aaaggatttc cgctatgcaa ccgacttgat tgagtttatc aaggaacgag
     9421 cccctcactt tgatattatt ggagcttgct atccagaagg gcatccagat tcgccaaatc
     9481 agatttcaga tattcaaaat cttaagaaga aagtggatgc aggctgttcg agcctcgtaa
     9541 ctcagctctt ctttgacaat gagcgcttct atgattttca ggacaagtgc atcttggctg
     9601 ggattgatgt tcccattcat gcaggaatta tgccaattct gaatcgaaat caggctctcc
     9661 gactcttgaa gacttgtgag aatatccatc ttccacgcaa atttaaagcc atcttagaca
     9721 agtatgagca tgaccctgag tcgctcagag cagcaggact tgcctatgca gtggaccaaa
     9781 tcgtggactt ggtaactcag gatgttgccg gtgtgcatct ctatacgatg aataatgctg
     9841 atacagcaaa atacatccat caagcaaccc atgccttgtt taatcaccag tctctaggat
     9901 aataaaagca aaccattctt ctcaggtgag gggaatggtt cctttttaat ggtaaagacc
     9961 tcacttttta agaaaaatat gataaaataa attctgtacg tacttgatac aaagatgaag
    10021 gtattaaata atacaatgca tttaaactgt aagatttaac gacacgagtg agtcaaatcg
    10081 atgttatttg acgagagagt tagtaaagca tttagctaat cgcccgatag cgattagcgt
    10141 gaaagcttta gatactttag tattaaacct ttctaatgat gtatcttgaa aactgaactt
    10201 gcctacaact ctgtggaaaa agataaatct ccctaggagc agtcgctccg tcgttcgatt
    10261 tcctattttc ctttgagttg cttgacggct tggtatcttg agtaattgaa cacggccgaa
    10321 aagctgtgta aaaaagataa actgtcttgt cttcatcgaa gacttcgtca gtttcctatt
    10381 tttactttgc ttttgacgtc cttggtatct tgatctttgt aggcaaggcg tataatttca
    10441 tcaatccaaa ggggattaaa atggcaaaac aagtgtttca aacgactttt gcgggtcgtg
    10501 agttaattgt agagactggt caggttgcta agcaagcaaa tggatctgtt gtcgtacgtt
    10561 acggtgagtc aactgtcttg actgctgccg ttatgtctaa gaaaatggca actggggatt
    10621 tcttcccact ccaagtcaac tacgaagaaa aaatgtatgc ggctgggaag tttcctggtg
    10681 gctttatgaa acgtgaagga cgtccttcaa cagatgcgac cttgacagcg cgtttgattg
    10741 accgtccgat tcgtcctatg tttgcggaag gtttccgtaa tgaagtccaa gtcatcaata
    10801 cagtgctttc ttatgatgaa aatgcatctg caccaatggc tgctatgttt ggttcatctt
    10861 tggcactgtc tatttcagat attccatttg acggaccaat tgctggggta caagtgggat
    10921 atgtagatgg ccaaatcatc atcaacccaa gtcaagaaca agcagagcaa tctcttcttg
    10981 aattgacagt agctggaacc aagcacgcta tcaacatggt agagtctggt gccaaagaat
    11041 tgtcagaaga aatcatgttg gaagcgcttc ttaaagggca cgaagctgtc aaagaattga
    11101 ttgccttcca agaagaaatc gttgctgctg tcggtaaaga aaaagcagaa gtggaattgc
    11161 ttcacgtgga tgctgaattg caagctgaaa tcattgcagc ctacaacagt gacctccaaa
    11221 aggcagttca agtagaagag aaattggccc gtgaagctgc aactcaagca gtgaaagacc
    11281 aagtgactgc cgtttacgaa gaaaaatatg cgaaccacga agaatttgac cgtattatgc
    11341 gtgatgtggc tgaaatcttg gaacaaatgg aacacgcaga agtgcgacgt ttaattacag
    11401 aagacaaggt gcgtcctgat ggtcgtaagg tcgatgaaat ccgtcctttg gatgcggttg
    11461 ttgacttcct tcctcgtgta catggttcag gtctctttac tcgtgggcaa actcaagctc
    11521 tttcagtctt gaccttggct ccgatgggag aaactcaaat cattgatggt ttggatccag
    11581 agtacaagaa acgctttatg caccactata acttccctca atattctgta ggggaaacag
    11641 gtcgttacgg tgcgccaggt cgtcgtgaaa tcggtcacgg tgcccttggt gagcgtgctc
    11701 ttgctcaagt cttgccaagc ttggaagaat tcccatacgc tatccgtcta gtagcagaag
    11761 ttttggaatc aaacggttct tcatctcaag cttctatctg tgcgggaact cttgccctta
    11821 tggctggtgg tgtgccaatc aaggcgccag tagctggtat tgctatggga cttatctcag
    11881 atggaaataa ctacacagta ttgacagata tccaaggttt ggaagatcac tttggagata
    11941 tggacttcaa ggttgcaggt actcgtgatg ggattacagc ccttcaaatg gatatcaaga
    12001 ttcaagggat tactgcagaa atcttgacgg aggctcttgc tcaagccaag aaagcgcgtt
    12061 ttgaaatcct tgatgtcatt gaagcaacca ttccagaagt tcgtccagaa ttggctccaa
    12121 ctgctccgaa aattgatacg atcaagattg atgtggacaa gattaagatt gtcatcggta
    12181 agggtggaga aaccatcgac aagattatcg ctgaaacagg tgttaagatt gatatagacg
    12241 aagaaggaaa tgtgtctatc tactctagtg accaagatgc tattaaccgt gccaaagaaa
    12301 ttattgctgg tttggttcgt gaagccaaag tggatgaagt ttaccgtgct aaagtcgttc
    12361 gtatcgagaa atttggtgcc tttgttaacc tctttgataa gacagatgcc cttgttcata
    12421 tctctgagat ggcttggact cgtaccaatc gtgtagagga tttggtagaa atcggggatg
    12481 aagttgatgt taaggttatc aagattgatg aaaaaggccg tatcgatgcc tctatgaagg
    12541 ctcttctacc tcgtccgcca aaacctgagc atgatgaaaa aggtgaaaag tctgagcgcc
    12601 ctcaccgccc acgtcatcac aaggatcaca aacctaagaa agaatttaca gaaacaccaa
    12661 aagattcaga ataagaaaag gagaaatgta tggggtggtg gcgcgaaacc attgatatcg
    12721 taaaagaaaa tgatccagcg gcccgcacca ctttggaggt tttgctgact tatccaggtg
    12781 tcaaggcctt ggcggcccac cgtctctcgc attttctctg gaagcacagc ttcaaactct
    12841 tagctcgtat gcacagtcag ttttggcgct tttggactca gattgagatt catccaggag
    12901 cccagattga ttcaggtgtc tttattgacc atggttctgg tctggtgatt ggagagacag
    12961 cgattgttga aaaaggcgtt cttctctatc acggagtgac tcttggggga acagggaaag
    13021 actgtggcaa acgccatccg actgtacgaa agggagccct catatcagcc catgcccaag
    13081 ttatcggacc tgtggaaatt ggtgaaaatg ccaaggtcgg tgctgcagca gttgtcgtag
    13141 cagatgtacc tagtgatgtg acggttgtcg gtattccggc caagattgtc cgtcttcatg
    13201 gtaagaaaga tgagcctgtt attcacgaag tcgaagaaaa acgagagtat tatgtcaata
    13261 aactcgagca ggctaaagat gccagtcaca gatcgtctgg tttgtagagg atacctatat
    13321 gattcaagca agaaacaagt taagccaaga ggagctatct gaggcgaaaa aagtaattaa
    13381 ctgttgccaa aactatgacg gtacctatcg cgatccctat ctctctaaca tgcttaattt
    13441 tgacccaaac atgcccgcct ttttccttta ttatgaaaaa ggcaaacttg ttggtttatt
    13501 aactgtctat gcagatgacc aagatgtaga agtgacgata ctggttcatc caggtcatcg
    13561 ccgtcagggg attgcgcgtg cattgtttac tagttttgag agagaaacag cttctttccc
    13621 tattcggtca gtcacttttc agacagaacg tattttttta gagaatcatc ctgactttgc
    13681 cagtaactgg ggactaatcg aggatgaaga gacagaaact tggttaggta aggatagaag
    13741 accttatccg ttagcaaatg tttcccatct tgaaattttg ttagcagata gttcgtatca
    13801 ggatcaaatt agtcaattaa aatttcaggc attttcagag gaacatgaat cgagagaagt
    13861 tgtggataga tatgtcgctg aagctctgaa agatccagaa agccgactat atattttatt
    13921 aaaagctggt caggttattg ggacttgcac ggttgattta tcgagcgata cgaattactt
    13981 ctacggttta gcaatatcag aacctgaacg tgggaaaggc tatggaagct acttagcaaa
    14041 atcccttgtc aaccaactaa ttgagcaaaa tgataaggaa tttcagattg cagtggaaga
    14101 tagcaatgta ggtgccaaac gtttgtatga aaaaattggc tttgtcaaac agacacaggt
    14161 ggtttatctg aatgagaaag gagcaaggga ttccgaagtg tagagacatt cggactgaaa
    14221 tttacttgag ctcttagttt agtgatgaaa ctaacagttc ttggatttta gctttcctga
    14281 ttatgattta tgattaaaat ctatgacacc atgtctcgtg atttgcgaga atttgtcccg
    14341 attgaggacg gcaagatcaa gatgtatgtt tgtgggccaa cggtgtacaa ctatatccac
    14401 gtgggaaacg cccgttcgac ggtagctttt gatacgattc gtcgctattt tgagtaccgt
    14461 gggtataagg ttgcctatat ttccaatttt acagatgtgg atgataagat tatcaaccgt
    14521 gccagggaag aaggcatcac gcctcaggag gttgcggata agtacatcgc tgcctttcgt
    14581 gaggatgtga cggccttggg cgtgaaacct gcgactcgcc atccgcgtgt agtggagttt
    14641 atggcagaca tcatccgttt tgtggaagac ttgatcgaga aaggctttgc ctatgagagt
    14701 caaggggatg tctatttccg tgtagaaaaa tcccacaact atgctaaatt ggctaataaa
    14761 accttggaag atttggagct aggtgcttca ggtcgtaccg atgaagaaac ggctcgtaag
    14821 gaaaatcctg tagactttgc tctatggaaa tcttccaaac caggtgagat ttcttgggat
    14881 agtccttggg gacctggacg tccgggttgg catattgagt gttcagtcat gtcgacagag
    14941 attttaggtg ataccattga tatccacggt ggtggagctg acctagagtt tccacaccac
    15001 accaatgaaa ttgcccaatc tgaagctaaa acaggcaagg cttttgctaa ctactggatg
    15061 cacaatggct ttgtcaatat cgacaatgtc aaaatgtcta agtccttggg taacttcatt
    15121 acggtacacg atgcccttaa aactcttgat gggcaagtac ttcgtttctt ctttgcgacc
    15181 cagcactacc gtaagcctat caacttcacg gaaaaggcag ttcgcgatgc cgagaccaat
    15241 ctcaagtatc tgaagaatac ttacgaacaa ccatttacag gaaacgtgga tgcccaagag
    15301 ttacaaaact ttaaagataa gtttgtagca gctatggatg aagattttaa tgctgccaac
    15361 ggtatcacag ttgtctttga aatggccaaa tggatcaact cagggaacta tgatgcaagt
    15421 gtcaagcaag ctcttgcaga tatgttagaa atttttggaa ttgtctttgt tgaggaagtt
    15481 ttggatgcag agattgaaga cttgattcaa aaacgccaag aggcgcgtgc caatcgtgac
    15541 tttgcgacag cagaccaaat ccgtgaccaa ttggttactc aaggaattaa gctccttgat
    15601 accaaggatg gagtgaggtg gacacgtgat tgatgtcaat ctcattaacg ggattgcgct
    15661 agcctttgag ggggatgcgg tgtattctat gtatattcgc cgtcacctca tcctcaaagg
    15721 tatgaccaaa cccaataaac tccatcaaga agcaaccaag tatgtgtcag ccaaggctca
    15781 ggctcgcctg attgctctca tgttggagga gcaggtccta acggaaaaag aagaagaaat
    15841 ctacaaacgt ggccgcaata ccaatagcca cacaaaggct aaaaatgcag atgtcgtgac
    15901 ttatcgtatg tccacgggat ttgaagcggt tatgggctat ctccatatga ctgagaatct
    15961 ggaacgtctt gagagtttgg tttcatggtg catccaaaaa gtggagggct agaacatgag
    16021 ggaaaaagaa ctacaagact ggtttcctga ggctcggatt tcagaccaac cagtagagaa
    16081 agagggctat ctcacgctcc ctttagcttc tcagcagtgg attttgctgg aggaagctgg
    16141 gctcagcgag cgtgaaaagc agttggttgc ccttttgacc cagcaggagc aggctcgttc
    16201 gctaaaccct tggtattcct atctggttga aggcaaggga caggcaccgc aagtttttaa
    16261 aaagattcag ttggtttatt gccatctttc ttattttcag caggaaaatc tggcttcttg
    16321 gctagatatg atgcggactc tttttccgaa ttgtcagaca gtgctacagg tcggagttca
    16381 ggattatgtt ttcgtgcttc aacaagacaa atacacttct gtaagagata ttttaagtga
    16441 tacgattgaa gcggttgagt atgactttgg acttcgtctt tctatcatgt tgggtcaggt
    16501 ttggtctcag acaggacatc aagccctatc agacttaatc aaagctgagc gggatttgtt
    16561 caagacatgg tggcgtcagg gtcaccaagg tgttcatact ttttctcagc tctatctttg
    16621 gagtatggga gaaagactcg tggacttgaa gccaattaaa gaatgtctac accagatgat
    16681 tttggatcaa gatcagattc aggaaatcat tctctctctt tgggaaaata gtgctgttct
    16741 cactaaaaca gcccagcaac tctatctgca ccgcaattct ctccaataca agattgataa
    16801 atgggaagag ttgacagggc ttcagttgaa agagttgacc gacctgacct tgtgttatca
    16861 attgatttta ggttctttgt caactatagt tggtttgtaa agaagttaat atttggagaa
    16921 gaggattgcc atcttctcca tttttatgtg cagagttata gtggcttgat gctgggaaag
    16981 tacactgtga ctgctaaaac attcctagaa gctgctttga tttccctaat ctatttatgc
    17041 aaattttatg ttattttact ataacagttg ttgctaagcc aaataatagt ggggaagttc
    17101 atttagacgt aagcattgaa gataatcagg gaggtagtgg gcataatttc agttctgttt
    17161 caagtagctc acaaacagct aaatatgaag aaactggtta taataacaat tcatcattat
    17221 atacaacgat tgataaaacg tctgatgcaa cagctctttt gaaattaaag ttgaataatg
    17281 ttgataatca acctgctact gaagttccta gttcaggaat tactgtaaaa ttaaatgcta
    17341 aagataatgc tggaaactgg acaagtgctt cgaataaaaa agaaataaca gtaaaaattg
    17401 tttctgctaa accgacatat ccagacaaaa tcttagtgaa aaatcctgat aatataaaag
    17461 atacagaaaa aaatgccatt attgaaaaat tgaaagaggc aaataaaaat tatccagcag
    17521 gagctccaac ctttgctaaa ggtgaaggag agcatgcaaa tgatattgta gcaacttatt
    17581 cagatggtac aacttattat gtaccgttaa atgatgtgac aaaatatgcg aggtagtggc
    17641 tgtaccactc acttattcac ctccccgtga tttgtagtag tgataggctt tctcactatt
    17701 attataaaac aaaataaaga gcacaacact ttttcattct gtgttgtgcc ttgagtgaaa
    17761 cgaaaggaat gaattataaa tatgaaaagt atagtcacta gcatagatga gcgcttgcgt
    17821 actcgcctac gagtgattat ctggaagcaa tggaagaaga aatcgagacg attatgggga
    17881 ttgcttaagt taggggttcc taaatggata gcagataagg tatctggctg gagcgaccac
    17941 tatcaattat agtaaaatga aataagagta ggacgaatcg atcagggcag ccaaatcgat
    18001 ttctaacaat gttttagaag aagagatgta ctattctagt ttcaatctac tatagtagct
    18061 cagaagtcgg tacttaaacg tgctatatca aaaccagtcc ttgaaaaacg tgaac
//
LOCUS       DAVHSL010000045        17969 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000045 DAVHSL010000000
VERSION     DAVHSL010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.046"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..441
                     /locus_tag="VVR39_001597"
     CDS             <1..441
                     /locus_tag="VVR39_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6031036.1"
                     /translation="LNANGDMATGWLQNNGSWYYLNANGAMATGWAKVNSSWYYLNAN
                     GAMATGWAKVNSSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLE
                     ASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            842..1963
                     /gene="mnmA"
                     /locus_tag="VVR39_001598"
     CDS             842..1963
                     /gene="mnmA"
                     /locus_tag="VVR39_001598"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU6031037.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2104..2502
                     /locus_tag="VVR39_001599"
     CDS             2104..2502
                     /locus_tag="VVR39_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6031038.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAF"
     gene            2569..4482
                     /gene="mnmG"
                     /locus_tag="VVR39_001600"
     CDS             2569..4482
                     /gene="mnmG"
                     /locus_tag="VVR39_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU6031039.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFENEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4861..6540)
                     /locus_tag="VVR39_001601"
     CDS             complement(4861..6540)
                     /locus_tag="VVR39_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6031040.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6542..6775)
                     /locus_tag="VVR39_001602"
     CDS             complement(6542..6775)
                     /locus_tag="VVR39_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU6031041.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7159..7377
                     /locus_tag="VVR39_001603"
                     /pseudo
     CDS             7159..7377
                     /locus_tag="VVR39_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7593..7745)
                     /gene="cibB"
                     /locus_tag="VVR39_001604"
     CDS             complement(7593..7745)
                     /gene="cibB"
                     /locus_tag="VVR39_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU6031042.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7747..7932)
                     /gene="cibA"
                     /locus_tag="VVR39_001605"
     CDS             complement(7747..7932)
                     /gene="cibA"
                     /locus_tag="VVR39_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU6031043.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8110..8793
                     /gene="tsaB"
                     /locus_tag="VVR39_001606"
     CDS             8110..8793
                     /gene="tsaB"
                     /locus_tag="VVR39_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU6031044.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLVHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8790..9227
                     /gene="rimI"
                     /locus_tag="VVR39_001607"
     CDS             8790..9227
                     /gene="rimI"
                     /locus_tag="VVR39_001607"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU6031045.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRGQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9217..10227
                     /gene="tsaD"
                     /locus_tag="VVR39_001608"
     CDS             9217..10227
                     /gene="tsaD"
                     /locus_tag="VVR39_001608"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU6031046.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10267..11573)
                     /locus_tag="VVR39_001609"
                     /pseudo
     CDS             complement(10267..11573)
                     /locus_tag="VVR39_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11848..12221)
                     /locus_tag="VVR39_001610"
                     /pseudo
     CDS             complement(11848..12221)
                     /locus_tag="VVR39_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12328..12621)
                     /locus_tag="VVR39_001611"
                     /pseudo
     CDS             complement(12328..12621)
                     /locus_tag="VVR39_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12864..13544
                     /locus_tag="VVR39_001612"
                     /pseudo
     CDS             12864..13544
                     /locus_tag="VVR39_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13670..15286
                     /locus_tag="VVR39_001613"
     CDS             13670..15286
                     /locus_tag="VVR39_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031047.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            15545..15973
                     /locus_tag="VVR39_001614"
     CDS             15545..15973
                     /locus_tag="VVR39_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031048.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            15985..16734
                     /locus_tag="VVR39_001615"
     CDS             15985..16734
                     /locus_tag="VVR39_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU6031049.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            16747..17919
                     /locus_tag="VVR39_001616"
     CDS             16747..17919
                     /locus_tag="VVR39_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU6031050.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
BASE COUNT         5506 a         3114 c         3934 g         5415 t
ORIGIN      
        1 ctcaacgcta atggtgatat ggcgacagga tggctccaaa acaacggttc atggtactac
       61 ctaaacgcta acggtgctat ggcaacaggt tgggctaaag tcaacagttc atggtattac
      121 ctcaacgcta acggtgctat ggcaacaggt tgggctaaag tcaacagttc atggtattac
      181 ctcaacgcta acggtgctat ggcaacaggt tgggctaaag tcaacggatc atggtactac
      241 ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag atggagatac ctggtactat
      301 cttgaagcat caggtgctat gaaagcaagc caatggttca aagtatcaga taaatggtac
      361 tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg tagatggcta tgaagtcaat
      421 gccaatggtg aatgggttta agccgattaa attaaatcat gttaagaaca tttgacattt
      481 taattttgaa acaaagataa ggttcgattg aatagattta tgttcgtatt ctttaggtac
      541 ctatcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct aacttgaaaa
      601 atagattaga gaaaaggggt tgttttattt attatagtta tttgaatgaa gataagaaga
      661 aggtatactc acgtcattca catgatctgt atattgacta taagttttaa aaaacaattt
      721 ttaagctctt ccttgtcttc tctaaccaag cgtgttataa tgaatactgc tcaagcgacc
      781 ttcaatcgtg aagcacacac gaccttcaat cgtgaataaa cgaatagatg ggagacttac
      841 catgagtgat aactctaaaa cacgtgttgt cgtggggatg agtggtggtg ttgattcgtc
      901 ggtgacggct cttcttctca aggagcaggg ctacgatgtg atcggtatct tcatgaagaa
      961 ctgggatgac acagatgaaa acggcgtctg tacggcgacc gaagattaca aggatgtggt
     1021 tgcggtggca gaccagattg gcattcccta ctactctgtc aattttgaaa aagagtactg
     1081 ggaccgcgtt tttgagtatt tcctagcgga ataccgtgcg ggacgcacgc caaatccgga
     1141 cgttatgtgc aacaaggaaa tcaagttcaa ggcctttttg gactatgcca tgaccttggg
     1201 ggcagactat gtagcgactg ggcattatgc tcgagtggtg cgtgatgagg atggtaccgt
     1261 tcacatgctt cgtggcgtgg acaatggcaa ggatcagacc tatttcctca gccaactttc
     1321 gcaagaacaa cttcaaaaaa ccatgttccc actaggacat ttggaaaagc ctgaagttcg
     1381 aaaactagca gaagaagcag gcctttcgac tgctaagaag aaagactcga cagggatttg
     1441 ctttatcgga gaaaagaact ttaaaaactt tctcagcaac tacctgccag ctcagcctgg
     1501 tcgtatgatg actgtggatg gtcgcgatat gggcgagcat gcaggtctta tgtactatac
     1561 aatcggtcag cgtggcggac tcggtatcgg tgggcaacac ggtggtgaca atgccccttg
     1621 gttcgttgtc ggaaaagatc taagcaagaa tattctctat gtaggccaag gtttctacca
     1681 tgattcgctc atgtcaacca gcctagaggc tagccaagtc cactttactc gtgatatgcc
     1741 cgaggagttt acgctagaat gtacggctaa attccgttac cgtcagcctg actctaaggt
     1801 gaccgtccat gtcaaaggag acaaggcaga agttatcttt gcggaaccac aacgcgcgat
     1861 tacaccagga caggcagttg tcttttacga tggcgaagag tgtctaggtg gtggtttgat
     1921 tgacaatgct taccgcgatg gacaagtttg tcagtacatt tagattgaca aattttctca
     1981 atttgctaca ataataacag caatagaaat gatggtcaaa gctcatggat gttgcaggct
     2041 tttttgtcct gcacttcttt gtagttttga ctgtttttgt gtcgtttaag ggaaaggaca
     2101 agaatgactc aacaagactt tcggacaaaa gtagacaata cggtttttgg tgttcgggct
     2161 acagccttga ttgtccaaaa tcacaagctt ctagttacca aagacaaggg caagtattac
     2221 actattggag gtgcgattca agtcaatgaa agcacggaag acgcggtagt ccgtgaagtg
     2281 aaggaagaac tgggtgtcaa agctcaagct gggcagctag cttttgtggt tgaaaatcgt
     2341 tttgaacaag acggcgtttc ctatcacaat atcgagtttc attatctggt ggatttgctt
     2401 gaagatgccc cgttgaccat gcaggaagat gagaaaaggc agccctgtga gtggattgac
     2461 ttggataagc ttgaggatat ccagctagtt ccagcctttt aaaaaacggc cctaccagat
     2521 tgggaaggcc aactaagaca catccatctt gagaaatagg agagaaatat gacatatcat
     2581 tttactgaag aatacgatat tattgtaatt ggtgcgggac acgctggggt tgaggcttcc
     2641 ttggccgcta gccgtatggg ctgtaaggtc ctgcttgcga ccatcaatat tgaaatgctg
     2701 gctttcatgc cttgtaatcc ctctatcggt ggttctgcca aggggattgt cgtgcgtgaa
     2761 gtcgatgccc tcggtggcga gatggccaag actattgaca agacttacat ccagatgaag
     2821 atgctcaaca cagggaaggg gccagctgtc cgtgctcttc gtgcgcaggc tgataaggaa
     2881 ctttactcta aggaaatgcg caagacagtt gaaaaccaag aaaatctgac ccttcgtcaa
     2941 accatgattg atgagatttt ggtggaagat ggcaaggttg tcggtgtgcg tacagccacc
     3001 catcaagaat atgctgctaa ggctgttatt gtgacgacag ggactgctct ccgtggggaa
     3061 attatcatcg gagacctcaa gtactcatca ggtcctaacc acagcttggc ttctattaac
     3121 ctagctgaca atctcaagga actgggcctc gaaatcggtc gtttcaagac aggaacccct
     3181 ccacgtgtca aggcttcttc tatcaattac gatgtgacag aaatccaacc aggagatgaa
     3241 gcgcctaatc acttctcata cacttcacgt gatgaggatt atgtcaagga ccaagtgcca
     3301 tgctggttga cctacaccaa tggtaccagt catgagatta tccaaaacaa cctccaccgt
     3361 gcgcctatgt ttacaggtgt ggtcaaggga gtggggcctc gttactgtcc gtcgattgag
     3421 gacaagattg tgcgctttgc ggacaaggaa cgccaccaac tcttccttga gccagaaggg
     3481 cgcaatactg aggaagtcta tgtgcaagga ctttcaacca gtctgcctga ggatgtccag
     3541 cgtgacttgg ttcattccat caaaggtttg gaaaatgcag agatgatgcg gacaggttat
     3601 gctattgagt atgatatggt cttacctcat cagttgcgtg caactttgga aaccaagaaa
     3661 atctcaggtc tcttcactgc tggtcagaca aatggaacgt caggttacga agaggcagca
     3721 ggccaaggga ttatcgcggg tatcaatgcg gctctgaaaa tccaaggcaa gcctgagttg
     3781 attttgaagc gcagtgatgg ttatataggg gtgatgattg atgacttggt gaccaaggga
     3841 accattgaac cctaccgtct cttgactagt cgtgctgaat accgtctcat tcttcgtcat
     3901 gacaatgctg atatgcgctt gactgagatg ggacgcgaga ttggccttgt ggatgatgaa
     3961 cgctgggctc gttttgaaat caagaaaaat caatttgaaa atgagatgaa gcgcctagat
     4021 agcatcaaac tcaagccagt caaggaaacc aatgctaagg ttgaggaaat gggcttcaag
     4081 ccgttgacag atgcggtgac agccaaggaa ttccttcgcc gtccagaagt ttcttaccaa
     4141 gatgtggtgg ccttcatcgg accagctgct gaggacttgg atgacaagat tatcgaattg
     4201 attgaaacag aaatcaagta tgaaggctat atttccaaag ccatggacca agttgccaag
     4261 atgaaacgca tggaagaaaa acgcattcca gccaatattg actgggatga cattgactct
     4321 atcgcaaccg aagctcgtca gaagttcaaa ctcatcaatc cagaaactat cggccaagcc
     4381 agccgtattt cgggagtaaa cccagcagat atttctattt tgatggtgta tctggaaggt
     4441 aaaaatcgta gtatttctaa aactcttcaa aaatcaaaat gatacgtcgt cggctgctta
     4501 cgaatgagtt caaagcttgg ctttgattca tctccaacct cccatagttc cccgaactat
     4561 gggagctaac tcaagttatg cattttccta gccttctggt ctgattttca ttgagtttta
     4621 atctcaaaag aaagcataga gaaaaacagc tccgaagacg gggctgtttt gttgacttgt
     4681 actcaatgaa aatcaaagag caaactagga agctagccgt aggttgctca aagcactgat
     4741 ttgaggttgt agatagaact gacgaagtca gctcaaaaca cagttttgag gttgtggata
     4801 gaattgacga agtcagtaac atatatacgg caaggcgaag ctgacgtggt ttgaagagta
     4861 ttattcttca tctggtgtga ggatcatcgg gatgatgatc ggttcacgtt cggtattttc
     4921 atagaggaag gggcgaatag cgttgacaat ggcaccattg acagattgca cgctagcatc
     4981 cttatttttc agtgcgatac gaatggcatt gaagaggata cgctggcttt ggcgaatcaa
     5041 gtcgccagac tctctcatgt agacaaagcc tcggctgagg atgtctggac cagatagaat
     5101 catctgcgat ttgaagtcaa cagttgcaac tgccagaacg acaccgtctt cagatagatc
     5161 gcgacgatct ttgaggacag ctgcgccaat ttcaccgata cgatttccat cgacatagat
     5221 atcttgggcg ttgaaatgac ctgcgatacg agctgagtca gcagtaaggg caagcacatc
     5281 gccattgctc atgataaaga tattgtcctt ctcaacacca gtatccactg ctagtccagc
     5341 gtggactttt tgcatgcggt attcaccgtg gacaggcatg aagtattttg gcttaatcaa
     5401 gcagagcatg agtttttgct cttgctgacc accgtgtcca gatgtatgga tattgttcac
     5461 tttaccgtgg ataacttcga caccagcttc agaaatgatg ttaatcagct tgttgacgct
     5521 agtagtgttt ccagggatgg gactagaaga gaagataacg gtatcacctg gttgtaattg
     5581 tacttgacgg tgggttccgt tggcgatacg agagagggct gccataggct caccctgact
     5641 acctgtacag aggataagaa cttctcctgc aggataatct ttgatttcat ttggctcgat
     5701 aaaggttccc ttaggagctt tgatgtagcc aagatcgatt ccgttgacaa tggccttttc
     5761 catagaacga ccaaagaccg caatcttgcg tccagtctta acagcagctt ctgttgcctg
     5821 ctggagacgg aagatatttg aggcaaagga tgcaaagatg atacgtcctt caataccttg
     5881 gataatcttc ataatggact gaccaacgac tttttcagag ttggtaaagg ttggtacttc
     5941 cgcatttgtc gagtcagaca ggagacagag cacgccttct tcaccaagcg cagccatacg
     6001 atgcaagtcc gcaggttctc caactggagt aaagtcgaac ttaaagtcac ccgtacagac
     6061 gattttccct tgaggagtat gaatgacaat ccccaaaggc tctggaatag agtgagtcgt
     6121 tctaaagaaa gttgccttga gatttttaaa ggtcaactcg gtgttgtggt tgatttcgta
     6181 aagtttggcg ttgcgcaaga ggccgtgttc ttcgagtttc ccacggatca aagccaaggc
     6241 aagcggtcca gcgtagatag ggacatttgc ttgcttgagt aggaacggaa tcccaccaat
     6301 gtggtcctcg tgtccgtgtg tgattaaaac agccttgacg cggtcgatat tgtccacgat
     6361 gtaagagtag tcaggaatga catagtcgat accaagcaag tcatcttctg ggaatttaat
     6421 cccagcatcg acgatgataa tctcgtcttg gtattcaatt ccgtaagtgt ttttcccgat
     6481 ttctcctaga ccaccgatgg caaaaacgcc gacttcttca ggtttaagag tgtaggccat
     6541 attagaactc cgtaatttcg aaggcgccag tttctttttc gtaatcgagc aatttgtcag
     6601 acaagagttc gatatactcg atattgtact ctgggcgatt ttcttcgaca agttggcgag
     6661 cagtgatacg gccctcaagt tctgagctgg catcgatgtc taggtaaagc gtgcgtgttg
     6721 tttcacggcg tgggctacgt tcttttgttt cttgataaaa aactttgtaa atcatatagt
     6781 tcctttctat ttacaggtca gcttattcca aacttttagc agatatttgc ttgatttcat
     6841 tccattttgt gtctagattg accttgattc gttacaatta tttcaattat accacaaaat
     6901 gaaaaattag taaaagacgg aaacgagaaa gttaggggac gatttctttg gtaagcgttt
     6961 gcaaaaataa agaaaatgta ttatgttgat aacggaagtg aaatttattg cttgtcataa
     7021 ttccatatag attttaagtc aaggaggttg ccctatgtat aacttatttg cttttgctat
     7081 cggagctcgc ttggtagctt ttattgtttt tgttgcttgc gtttatgcgg ggaatcttct
     7141 atttgccaaa ctggaacgat gacaaaccaa gttcttgtgg aaaatgacct ttgtgactct
     7201 ctactcgctt tttctcctcc tcatgaccta tgtcgtttgg tttgtatttt actttggatt
     7261 aaatgcttag atgccctgct tatgctgggg ttttttgttt ggggatgtag agatagtaga
     7321 tttacgacac gaaaattcta ccccatctat caagatgagg tggtttttgt attttttaga
     7381 aatgacatga taatggtatt ttcagagctt attagtttta tggtaatcat tcttctgctc
     7441 aaaaatagag ttgaagcata aaaataaaac aatacaaaca gataaatcga atggtaaagg
     7501 gatagtagta atgttcaaat cattgagaat gctgagcaaa ctgtaagaga tgaagacaat
     7561 aaaatttatc cttctaaaaa tgtgtttctt atctagcatg atttaccaaa ctttttacga
     7621 aggtcttttc caatggtata acctgccata aataaagcga taccaacacc tacaccaaag
     7681 ccacccttga tttcttgcaa ttccttatta gaaatttcac gatagttgtt caaatctttc
     7741 atcatattaa tctcctccta aaaaataacc agctgccaaa ccagaaccta taagtgctgt
     7801 tccacctgca atagccttcc aagatactgc tactccaaag ataaccaagg gagcgagacc
     7861 gccatcaata tctgataatt cattttcaga taaggataaa aattgattgt caagaatgtc
     7921 aaaatttgtc attgaatttt cctccttttt tcttgttcac ttttatattc ggaaaagaaa
     7981 aggaaaagtg agcatttttt taaattattt ttagttaagt gagggcactc ttgtctgggg
     8041 gcaaagaaaa ttcccatgtg ccagcttttg tagtataata gtaagcagac aaaaagatag
     8101 gaatgtgtta tgaaagtatt agcttttgat acgtccagca aggctctttc tctcgctatt
     8161 ttagaggaca agcagattct tgccgagatg acgattaata ttaagaaaaa tcacagtatt
     8221 accctcatgc ctgccatcga ttttttgatg gcaagtttgg actggacacc caaggatttg
     8281 gaccgaatcg tggtggctga agggccaggt agctacacag gcttgcgaat tgcggtagcc
     8341 actgccaaga ctttggttca tactctgaac atcgagttag ttggtatgtc tagcctcttg
     8401 gctctggtac cctaccaaca agaaggcttg ttcgtctctt tgatggatgc gcgtcgcaac
     8461 aatgtttatg caggatttta tgaaaatgct aaacccgtca tgccagaagc tcacttaccc
     8521 tttgagcgag tgattgagtt aatcaagggt gctagtcagg ttacctttgt cggagaagtt
     8581 ggcccctttg ttgagcagat tcaaaaacac ttgccaagga ctaatttcaa agaaaccttg
     8641 cccaatgcag ctaatctagc tctatgggcc tgggacaagg aagcagactc cttgcatgat
     8701 tttgtgccga actacctcaa gcgtgtcgaa gctgaggaaa actggctcaa gaatcacacc
     8761 gagtctggcg agtcttacat taaacgctta tgatagaaat caaacgaatc caacagcaac
     8821 ctgccttggc tcaagatatc tacgctgtca tggcagctgt ttacccagtc agtccttgga
     8881 cactagaaca aatccaagca gatctgtccc aagaccagac ttggtatgca ttggcttatg
     8941 atggggcaga agtgattgga tttctagctg ttcaggagac tctctttgaa gcagaagtcc
     9001 tgcaaatcgc tgtcaaagga gcctatcagg gtcagggaat tgcgtcagcc ttgtttgctc
     9061 aattgccgac agataaggag attttcctcg aagtcagaaa gtcaaatcaa cgagggcaag
     9121 cattttacaa gaaagaaaag atggcagtta tcgctgagcg aaaggcctac taccatgacc
     9181 cagtcgagga cgccattatc atgaagagag aaatagatga aggatagata tattttagca
     9241 tttgagacat cctgtgatga gaccagtgtc gccgtcttga aaaacgacga tgagctcttg
     9301 tccaatgtca ttgctagtca aattgagagt cacaaacgtt ttggtggcgt agtgcccgaa
     9361 gtagccagtc gtcaccatgt cgaggtcatt acagcctgta tcgaggaggc attggcagaa
     9421 gcagggatta ccgaagagga cgtgacagct gttgcggtta cctacggacc aggcttggtc
     9481 ggagccttgc tagttggttt gtcagctgcc aaggcctttg cttgggctca cggacttcca
     9541 ctgattcctg ttaatcacat ggctgggcac ctcatggcag ctcagagtgt ggagcctttg
     9601 gagtttccct tgctagccct tttagtcagt ggtgggcaca cagagttggt ctatgtttct
     9661 gaggctggcg attacaagat tgttggggag acacgagacg atgcagttgg ggaggcttat
     9721 gacaaggtcg gtcgtgtcat gggcttgacc tatcctgcag gtcgtgagat tgacgagctg
     9781 gctcatcagg ggcaggatat ttatgatttc ccccgtgcca tgattaagga agataatctg
     9841 gagttctcct tctcaggttt gaaatctgcc tttatcaatc ttcatcacaa tgccgagcaa
     9901 aagggagaaa gcctgtctac agaagatttg tgtgcttcct tccaagcagc tgtcttggat
     9961 attctcatgg ctaaaaccaa gaaggctttg gagaaatatc ctgttaaaac cctagttgtg
    10021 gcaggtggtg tggcagccaa taaaggtctc agagaacgcc tagcagccga aatcacagat
    10081 gtcaaggtta tcatcccccc tctgcgactc tgcggagaca atgcaggtat gattgcctat
    10141 gccagcgtca gcgagtggaa caaagaaaac ttcgcaggct gggacctcaa tgccaaacca
    10201 agtcttgcct ttgataccat ggaataagga gtggctcttt gtcaagtgta gtgggtaggc
    10261 gaaaagctac aatctggaga gtacgaaatt cgtactctct tttttgatgt tcaaagtcat
    10321 caaaatccgt tttttaaaat tgttaaagtt ccggaaacca aaggctttgc gcttgataac
    10381 cttaatcaaa ttattggtcg cttcaagttt agcgttggaa taaggcagct taagtgcgtt
    10441 gataatctta tctctatccc ttaaaaaagt ccaaaagacc gtttgaaaaa gcggatgaac
    10501 cgttggcagt tcttgctcaa tcaatccaaa gaaatggtcg gcattcttct cttgaaaatg
    10561 aaagagcagg agttgataga gttcgtagtg aacctgtaat ccctcagagt aagaaagcag
    10621 cttatctcgt acttcccgat gggttaagtg cattcgaaac gtgggctgat agaatcgttt
    10681 ctgacagagc ttgaagctat cctggtgtag taaatcagtc cagtggactg atttagcccg
    10741 agcctagaaa cgaaaaagcg agggttccaa aagcgcttga gcgcccgata ctccaaggat
    10801 tttcggtcaa attggttcat gatttggatt cgtactcggt tcatagctcg gctcagatgt
    10861 tggacaatgt ggaagcggtc aagaacaatc ttcgcctttg gaaagagttg cttagcgagc
    10921 cgataataag ggctgtacat gtccatggtg atgacctcga ccagctcccg aacctctctc
    10981 tgatagcgtt ggaaatggtt tcgaatcacc gcatgagttc gcccgtctaa aattgcgagg
    11041 atggatttgg actcaaaatc ttgggcaatg aagctcattt tgctcttttt gaagctatac
    11101 tcatcccaac tcataacttt tggcaacttg gtccaatcgg tttcaaactt aaattccctc
    11161 agttttcgga tgacggtgga agttgagacc gccaatctgt gggcaatctc agtcatagac
    11221 tgcttttcaa ggaggagctg agcgattttt tgtctcacca tgttggaaat ctggcaattt
    11281 ttcttgacaa tggatgtttg agaaacgacc accttaaggc aattcttgca ctgaaagcgg
    11341 cgctttttga gatgcagtac cgtgggtaaa ccctgacagt cgagaagcgg aattttagag
    11401 gctttctgga agtcgtattt gatcatcttc ccttgacaat gaggacaagg aggagcgggg
    11461 gaatccaact ttgcctgaac gactagatgg gtttggtatt tcagaacaga caagattttg
    11521 atatttttgt cttccaatcc gagcaaatct gtggtattct taagttgttc catatggacc
    11581 ctttctaatg agttggttag acgcttttca ttataggtca tatggggctt tttttctaca
    11641 agaaacgacc ctataattcc tggggtggga ttacccacta cagaaattat agagcccaaa
    11701 cattccaaag tcttgtctga ctctggaatg ttttctgttc acagttgttt tgtaactgcc
    11761 taataagtaa ccgcgctata acgaggtatc taccgagatt gtcaattctc cagtatactg
    11821 ttataaaaaa caaaactgga ggatttttta tgtcccccca tcgtcccatc gactgttccg
    11881 tagctgccca ataacggagt atagtcggct gaaacaagaa taggacaaaa gtgcctcaag
    11941 aaaagcatcg taatttgaca atattattct gagatgtttt tgatgtaagc ccatattttc
    12001 tcaatgggat tatactcggg tgaataggta ggaagtggta acagtctatg ccctgctcct
    12061 tacacatgtt cattctgtga aaccttgcat tgtccataat gataagggat ggtgtatcta
    12121 atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca agcttcgaaa
    12181 aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg aaacaaaaaa
    12241 gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct cgatcttaat
    12301 tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc gatcatattc
    12361 gagataaaaa taggtcttaa cccctgtctc ataaatataa ataggagtca ggtagcttaa
    12421 gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc agtaggtaca
    12481 gctctttttt agactatatc ccatagcctt tagagcgtaa tgaatagttg ttggaggaca
    12541 gttgaattca gcagctattt cagtcaaata agcatcggga tgagtttcaa tatagatctt
    12601 taatttatct ctatcaactt tttcaattaa tagtggaagt tttcttaaag ttagtgtatt
    12661 gaaacgtttt tatacagtgc taaaatttga agtgtagtgc agatatattt gtaatagtat
    12721 tatagcaatt ctttgaagaa ggtcgagaca agagaaaata ggtatctttg agatataagc
    12781 atgatttact ataaaattat tgagttattc ataaaaattt ctctatcaaa tatcataatg
    12841 cgtcgtttaa ggagatggtt acaatgcaat atagttgtgg aaaaataaat attaatatcc
    12901 ctgatggata tggagacatt aaggatatag tgttttcggc tcatattata gttaggtata
    12961 ataatggaca ttgtggaggt atagatccgc atataattgg actttgtaaa aagcagatca
    13021 gaaggatgtc tctatatcct attttgataa tcgtatctag agattcaaag gttattgatg
    13081 attataaaaa tttagatatt gcctatgttg attgtactca atgttcaaat aattttgaaa
    13141 ctgccttaca cgttaaaaat attttaaaat tattaaaaat ccaacttata cactgtcatg
    13201 gctactcaac taattatttt ttatatatgt taaaaaaact tgacaagaat ggatttggaa
    13261 aggttaagac agtgataaca tgccatggat gggttgaata taacttaaaa aagaaattct
    13321 tgacttattt tgatttttgg acatattcta tgggagatgc ttttatttgt gtatctgaaa
    13381 ctatgaaaaa aagattggag agtataataa aaaataagaa gatagttgca ataaataacg
    13441 gaattaatgt atcaaatagc gatttagatg tagtaggtgt tcaagacttt aaaaaagaat
    13501 tttgtattcc aaataacaaa aaaatcattt gttatgttgg aaggcaagag aagaaaaaat
    13561 ttttaacgaa tttctttttt tgaaatacat gttattatat aattttggtt ttttctattg
    13621 tatatatgac aactatgttc aattaaaatt tagaaagtga gaaactattg tgtatactat
    13681 tataaaatca aatataaaaa aatttagttt attaacgata tttattgttg ctggtcaatt
    13741 attgctaatt tatgcagcaa ctattaatgc tctggtgttg aatgaattaa ttgcgatgaa
    13801 tttagagcgg tttttgaaat tgtcaatcta ccaaatgatt gtctggtgtg ggataatatt
    13861 ccttgactgg gtagtgaaaa attatcaggt tgaagtgatc caagagttta atctagagat
    13921 tcgaaataga gttgccacag acatctctaa ctctacctat caagaatttc atagtaaatc
    13981 atcaggaaca tatctttcgt ggctaaataa tgatgttcag actttaaatg atcaggcttt
    14041 taaacaactt tttttagtaa taaaaggaat ttctggtact atatttgcag ttgtgactct
    14101 taatcactat cattggtcat tgactgtagc caccttgttt tcattaatga ttatgctact
    14161 tgtaccaaaa atctttgcat cgaaaatgcg agaagttagt ctaaatttaa ctaaccaaaa
    14221 tgaagctttt ttaaaatcta gtgagactat attgaatgga tttgatgtgt tagcgtcctt
    14281 gaatctttta tatgtattgc ctaagaaaat taaagaagca ggaattttat taaagatggt
    14341 tatacaaaga aagacaactg tagaaacgtt agcaggcgct attagcttct ttctcaatat
    14401 tttttttcag atatctctcg tttttttaac aggctatctt gcaataaaag gaatagtgaa
    14461 aattggtact attgaagcaa taggagcact aacaggtgtt atttttacag cgctaggtga
    14521 attaggaggt caattatcct ctattattgg tacgaagcct atttttttaa aattgtattc
    14581 aattaatcca attgagtcaa ataaaatgaa tgatatcgaa ccaaatgagg tgaatagaga
    14641 ttttccgtta tatgaagcaa aaaatatttg ctataagtat ggagataaag aaatattaaa
    14701 aaacttaaat ttttgttttc aacgtaatga aaagtattta attttaggtg aaagtggaag
    14761 cgggaaatct acattattaa aattattgaa tggctttttg agagattata gtggagaatt
    14821 gcgattctgc ggggatgata taaaaaaaac ctcctattta aatatggttt cgaatgttct
    14881 atatgtagat caaaaagctt atttgtttga aggtacgatt agagataata ttttattgga
    14941 agaaaattat actgatgaag aaatactaca gtctttagag caagttggtt tgagtgtaaa
    15001 agattttcct aataacattt tagattatta tgttggtgat gatgggagat tactgtcagg
    15061 agggcagaaa caaaaaatta ctttagctag agggctaatt agaaataaga aaatagtatt
    15121 aattgacgag ggaacttctg ctatcgatag gagaacttcg ttagcgattg aacgtaagat
    15181 attagataga gaggatttga ctgtcattat tgttacccat gctccgcatc cggaacttaa
    15241 acaatatttt actaagatat atcaatttcc aaaggatttt atttaagaat ataggggagg
    15301 gaaacatgag attctattgt gaagcttatg aggtaattac tgaagagaaa aaagtatcat
    15361 ttttttatgt agatgaaaaa cccttaaggt atctgttatt tgactatata tttctactag
    15421 ttctagctaa aaaaatatcc caatcttatg aactgcaccc caaaagttag atttattctg
    15481 tctaactttt ggggtgcagt tcattttgca tagttttggc attcatccta gatatccata
    15541 taaaatgtct gagattgttg aaatgtctaa aaaaatatca gatctaaacg ataaaaaaga
    15601 atttcacaaa aagaactgtg agttgaggtt tcaagatagt gttcttgata acataaatag
    15661 tgtcccgggt acaactcatt tatttagttg tttaaatatt caaacattag taaaaattat
    15721 tttatatatt tttcgataca acagttgtat gaaaatattt aattttagag ataaagagct
    15781 tatctttttt aataagattg taaatgggct gatacaaaat attgaggaga atttagagga
    15841 tgatattgaa aggatattga aatatttata tatatgttta tttaacgaaa tattcattat
    15901 taagaataag gtgaattttt ttgatgatgt ggaatttaat cagacactta gtgagttttt
    15961 agataaattg tagagggaat ggttatgagt aacaatacta agtatatctt tttatctcca
    16021 catttagatg acgcaatttt ttcctgtggt gattatattt caaaattaac ttcagaagga
    16081 gaaattgtac ttgttattac tatattttct ggttaccctt tgagccaaca gctacagccc
    16141 tctgctaagc aatttcataa gttgtgtaac cttgggaaat atccgattga agaaaggaag
    16201 aaagaagaca ggttagcttg tgaacgtcta caatgtgatt ttagacactt atcgtactat
    16261 gaatgtctct ataggaaaga tagaaatggc aattttctat accgtcatat ctatagtgaa
    16321 ttaaaaaatg aggacacatt aaagaatgat atcataaaag agctgttaat gcatttagac
    16381 gacaaatgtg tcgtatattg tccgctttca cttggtgacc atgttgatca tgtttttgtg
    16441 aatagtattg gaagggcgct tgaatttatg cgttataaag taatatatta tgaggacttc
    16501 ccatatgtaa gtgatagtag tatggttagt tatatgggaa aaactaaaga attaaaaatg
    16561 tatcaagagg aacttgatga aaaacattat attgatagaa tatcatcaat attgtgctat
    16621 aaatctcaga ttttgataat ctggaaatca gttgaaaaac ttttaaacaa tattaaagag
    16681 ttgtatttaa ggaatggggc agcttattct attagatttt ggattaagaa ataaggaagt
    16741 agttttatga atatagcagt aattggtttg gggcatgttg ggctggccta cgcgttacta
    16801 tttgcatcta aatataaagt tgttgcatat gatatagatt ctgtaaaaat aaataattta
    16861 aaaaagggca ttcttccatc taaaaatgaa gagcttatga agtttttttg cgagaataac
    16921 ttaaatatta ctttttttga tacattttct gaaattaaaa ataatattga ttattatatt
    16981 attgcgcttc cgacagatta tgatgagaaa attggtagtt ttaatacata tgaaatcgaa
    17041 caaacggtat cgaagattct gagggtaaaa cctaatggaa agattatttt aaagtcaaca
    17101 gttccgatcg gcttttcaaa caaattaaaa aggctgtttg atacaaaaaa tatcattttt
    17161 gtccctgaat ttttgagaga aggttgttct atatatgata atttatatcc aagtcgcata
    17221 gttgttggag atgagacagt tgaaggaaga aaaattgcag agttgttcct ttcgattagt
    17281 actcatagta ctgccaatat taaaaatgtt atgttagttt ctcctactga agcagaagca
    17341 attaagcttt tttctaacac attcttagct ctccgtgttg ctttttttaa tgaactagat
    17401 tcttttgctg agaggagaag tttaaatgct gaagttgtaa taaaaggtgt ttgtttagat
    17461 ccaagaattg gaaattttta taataatcct tcttttggat ttggaggata ttgtcttccc
    17521 aaagatacta aacaattaaa aaaagaattt atagaaataa atgccccagt gatagaagcg
    17581 attgatattt caaacacaaa tagaaaacag ttcatagtta aacaaatatt ggaacgaaag
    17641 ccaaagatag taggaatata taaattgggg atgaaatata attcagataa ttacaaagag
    17701 tcagctattt taagtataat taatgaacta ttgattgtcg gtataaaaat tttagtatat
    17761 gaaccaaatt taaacgttag tatagataac gtaatttttg aaaagaattt tgaactattt
    17821 acaaaacaaa gtgatctaat tgttgcaaat agatgggata ggggccttga agcttataaa
    17881 gataaagttt acacaagggg gatctggata agagattaac tattgatatt aaagaggcaa
    17941 taatttataa aatttgtaca aaaaaatgt
//
LOCUS       DAVHSL010000046        16895 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000046 DAVHSL010000000
VERSION     DAVHSL010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.048"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            210..1655
                     /gene="cps4A"
                     /locus_tag="VVR39_001617"
     CDS             210..1655
                     /gene="cps4A"
                     /locus_tag="VVR39_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU6031051.1"
                     /translation="MSRHFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1657..2388
                     /locus_tag="VVR39_001618"
     CDS             1657..2388
                     /locus_tag="VVR39_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEU6031052.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2397..3089
                     /gene="cpsC"
                     /locus_tag="VVR39_001619"
     CDS             2397..3089
                     /gene="cpsC"
                     /locus_tag="VVR39_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU6031053.1"
                     /translation="MEKQNTLEIDVLQLFRSLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVSRDQGEKSGLTNQDLQAGSYLTKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVAVPVDTRIVSISVNDQVPEGASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKLNTLIGFLVGLIVINVTVLLLELLDTRVKRPEDIEDALQMT
                     LLGVVPNLDKLK"
     gene            3099..3773
                     /locus_tag="VVR39_001620"
     CDS             3099..3773
                     /locus_tag="VVR39_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU6031054.1"
                     /translation="MPTLEIVQKKLEFIKKTEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSINIAWSFARAGYKTLLIDGDIRNSVMSGVFKSREKITGLTEFLSGTTDL
                     SHGLCDTNIENLFVVQSGAVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGVVI
                     DSAIITQKCDASILVTATGEVNKRDVPKAKQQLEQTGKLFLGVVLNKFNVQHEKYGSY
                     GNYGKR"
     gene            4177..4770
                     /locus_tag="VVR39_001621"
     CDS             4177..4770
                     /locus_tag="VVR39_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6031055.1"
                     /translation="MYSILKRLGDISISLIVITLFCPFFILIAIAIKFDSKGPVIFKQ
                     KRFGIHKKTFYVFKFRTMKVETPKNVATRDLQNPEQWITRVGTFLRKTSLDELPQLCN
                     ILVGDMSIVGPRPALWNQFDLIEERDKYGANDILPGLTGWAQINGRDNLSIDMKAELD
                     GYYVTHKSLLMDIRCIVRTIPYVLKRKGIVEGSQKES"
     gene            4779..6005
                     /locus_tag="VVR39_001622"
     CDS             4779..6005
                     /locus_tag="VVR39_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6031056.1"
                     /translation="MKILFVSQHYRPEPFRLSDICEDLVERGHEVTVLTGIPNYPEGK
                     TYADYRNNKNRRETIEGVTVFRSYTIPRGKSTLHRILNYFSFAISSSIGVLLGQYKAK
                     DGSEFDCIFVNQSSPVMMAWAAMAYKNKYKKPMFLYCMDVWPDSLTVGGVKQDGLIFK
                     LFKFISKKVYRASDYIFVTSPSFKNYFVNQFDITEQKITYLPQYAEDLFIPDESRVNK
                     ESVDLTFAGNIGKAQNLETILKAASLIEKNTDLPKKIQFHFVGDGTELLSMKALAHEL
                     ELKNVSFYGRRSLEEMPTFYKKSDAMLVSLIGDSIVSRTIPGKVQSYMAAGKPIIGAI
                     SGDTKTIVEEAKCGFVSPEQDVEQLAQNICKFSMLSTEEQRELGKQARCYYGKHFSKE
                     QFMTQLENYLREGFSS"
     gene            6236..7441
                     /locus_tag="VVR39_001623"
     CDS             6236..7441
                     /locus_tag="VVR39_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HEU6031057.1"
                     /translation="MESRKKFVCFPNSSLRFYILQAAIALSILSQAPYIWKFSGIPTQ
                     LLIMPLWILLGVVSIFSRIDMERSFLFFLLTIGCLISTIALLDIVTGVSYVFNGLSQQ
                     LYLAVGILVLGYWNADVIVHYWKIITMTFLGACLLISVDIYFHYFQGHTFSNIDYVYR
                     AKNSAASIFLSAVILNLSLYNRKWALWRKVLLLASSGLLIYMCILMRSRAVLLAAAVL
                     PLVYIWFQETSLGHKIGRTLGVSTVVGAFLLNSAIYDFFINNLFLRVTSEYRPSSLTL
                     DYVSSNRFVYFEIFAKEISGHELTGIGYYYMDNFFLESFLNYGYIVGTAFVLIALSPM
                     IYALLQRSSSHRFRMLFLALAFSYTVNALFEGYAPFGPGAKSFILWLVFGCLLNTRIG
                     KVGEHSETS"
     gene            7419..8888
                     /locus_tag="VVR39_001624"
     CDS             7419..8888
                     /locus_tag="VVR39_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEU6031058.1"
                     /translation="MNILKQVSLKWNYVFNLANKLFSLTIPLIVTPYVTRVFSSDHFG
                     IYTYTNTVASYFVTFTLMGISMYGSKKISLKRHDEIAVNDEYASLLTVQLLNVGLATL
                     TYFLYVTFFVNNNQVIYWIQMLYVISAGFDMTWFLSGLERFREIAVRNIIVNVLSALM
                     IFFFVHTEADLAIYTLIKVGTIFISQIVIFLPVVRMQRFYLAGAEHIRRTYRGLLLLF
                     IPVLADTLFQTMDKIMLGIYASYTAVGLYYSSRMVTDIPQTVITSLNIILFPRITHLL
                     SQNKKVESNKLFYQSFILIIALSLATAFGVSAIARDFVGIFFGSSYGAVADYVPSLSL
                     YICLAAWSGTIRYQYLIPHSLERVYVVAIILGSGINLVLNSLLIPFLGVYGSILATII
                     SELVICVYQTYPIRKEIPLKGLLGYVIIFAGLSFLMYLSLGWLRLLLLGRLSTVLLLA
                     SEIIFGILVFTIATITYIYLGNPILWQAIKKYIESRKNV"
     gene            8885..9766
                     /locus_tag="VVR39_001625"
     CDS             8885..9766
                     /locus_tag="VVR39_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6031059.1"
                     /translation="MISIIMPAYNEEKNIGAAIASIQQQTYTDFQLIIVNDGSTDDTA
                     AIVQEKIMGDERIVFLNPGKIGKVPAYNLASQYVKGDWIYFMGADDQLPLDAFEKWNK
                     EAQKWNPAEKVALRARMRMVSDSHKYDGLVLPKKNTVRNFSGPLTLLSKEMHRFILPI
                     PEAYPNEDIWWGLCIEYFGDRVSLIEDVVVYYRVHEGNSISRTSTFEPFNEKYHIRQI
                     IRRDFLERFSNHLTADQKTKLQRELKLEEARYKGNRLPILLMPGISAVHRLRLLFLSG
                     RRSYVLKVKLDRFFLGH"
     gene            9780..10865
                     /locus_tag="VVR39_001626"
     CDS             9780..10865
                     /locus_tag="VVR39_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6031060.1"
                     /translation="MSKKKISYVTNNIAPFRVMLLDELAKHAEVTLFYVHEIEAGVKA
                     EYVKLRPVRTKLQSITELGLFQTFQMLKEMDMVFFDGYTGWEKMFLMSSMWLTRRQYA
                     ISVDGIINHSNISLKQRLLDFIKSVALSKAEFVLSTNTPTDAYIQQLAPKAKIKRHIF
                     STLSQDDFKNMIEVASDTVFTRYSIRKSEKNLLFVGQFINRKGVDELLAFMKEHEADT
                     SLQLIMVGGTREELSVFETEIPSNIHIIPFLEKTDILELMRVADVFVLPTREDIWGLV
                     IIEALSMGIPIVSTDRCNAALEFVRDGENGYLMQEVTAVELANKLKATFKLDAEHVAR
                     YDQKLMQDYNLEGSAKNIMDILEGSHV"
     gene            10858..11664
                     /locus_tag="VVR39_001627"
     CDS             10858..11664
                     /locus_tag="VVR39_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031061.1"
                     /translation="MFNSSCALFIVSCETNQQVVNLLIQSMRQQISHMVSIYVSSDGP
                     LLITDPSVRVLIGQEEVFGDRVATALEQVTEERVIVFCDDFIVEKPAKIEELEELLSL
                     MEEDTSIASIALSQISGGNTPERIAEHYIRRTKYAPYKTTLQCAIWKKSSLIQFMKGS
                     PSPWEFEIYHNFKTYLTKEKFYALEDDMFQPIPYNRGKLIIRGKVVKPEKERLEELLG
                     YSLDLSDFPETESFVQGENLTVGYRLKRKIKLLEKEIIYRLKSKIKNKKK"
     gene            11897..12934
                     /locus_tag="VVR39_001628"
     CDS             11897..12934
                     /locus_tag="VVR39_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6031062.1"
                     /translation="MFTKKTLLITGGTGSFGNAVLKRFLGTDISEVRIFSRDEKKQDD
                     MRHEFQAKMPEVADKIRFYLGDVRDLASVKNAMIGVDYVFHAAALKQVPSCEFFPVEA
                     VKTNVLGTENILTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMMEKIAVAKSRTVEE
                     DQTKVCVTRYGNVLCSRGSVIPLWIDQIKQGNPITITEPSMTRFIMSLEEAVDLVLFA
                     FEKGKTGDILVQKAPACTIEVLAQAVTELFAPNQDIKVIGIRHGEKMYETLLTTEECT
                     NAIDLGGFYRVPSDNRDLNYDKYFNEGDAKRNPLIEFNSSNTELWNVEQVKEKLLLLP
                     YIREELASLNQ"
     gene            12943..14154
                     /locus_tag="VVR39_001629"
     CDS             12943..14154
                     /locus_tag="VVR39_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU6031063.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQYHKVIAVDVIPEKVELINRRQSP
                     IKDDDIETYLVEKELDLVATLDGNEAYRDADFVIIAVPTNYDSKKNYFDTSVVEAVIE
                     QIIAVNLKATIVIKSTIPVGYTESLRTRFGQFKILFSPEFLRESKALYDNLYPSRIIV
                     GADLRDTEQVVQAERFATLLQEGSLKPDVETLIMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTKSIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDSKQLLANYHDVPQ
                     NMMTAIVESNRTRKYFIADRILKNALELSDGNQTIIVGVYRLTMKSGSDNFRQSSIQG
                     VIKCLKAKGVEVIIYEPTLEDHSFFFGNQVVNDLEVFKSSSQVIVANRMEKSLYDVLE
                     KVYTRDIFQRD"
     gene            14173..15402
                     /gene="cps4K"
                     /locus_tag="VVR39_001630"
     CDS             14173..15402
                     /gene="cps4K"
                     /locus_tag="VVR39_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4K"
                     /protein_id="HEU6031064.1"
                     /translation="MPLKILVTGSKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILEKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLVGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCHNLAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPNSLVMPEIPQGSFKKKLYSTYLSYLPV
                     DKFKFPLKMNIDERGSFTELLKTENKGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLVTVMWAN
                     ESFDPRHPDTFFEQVEK"
     gene            15403..16587
                     /gene="cps4L"
                     /locus_tag="VVR39_001631"
     CDS             15403..16587
                     /gene="cps4L"
                     /locus_tag="VVR39_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4L"
                     /protein_id="HEU6031065.1"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAIAAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDIISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLSAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAEDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
BASE COUNT         5249 a         2578 c         3503 g         5565 t
ORIGIN      
        1 actagagtag tacacctctg cttctaaaaa atttttagaa atcgatttaa ctgtcctgat
       61 cgatttgtca tgttcttatt tcattttact atatttttgt ttcgcgggaa gtctactaag
      121 atacttaaag atgcagatag taaaaaaatg tagacattac cgtaaaaaag tgatataatc
      181 gtatgatgtt caaggtatag gtgttaatca tgagtagaca ttttaaaaaa tcacgttcac
      241 agaaagtgaa gcgaagtgtt aatatcgttt tgctgactat ttatttattg ttagtttgtt
      301 ttttattgtt cttaatcttt aagtacaata tccttgcttt tagatatctt aacctagtgg
      361 taactgcgtt agtcctacta gttgccttgg tagggctact cttgattatc tataaaaaag
      421 ctgaaaagtt tactattttt ctgttggtgt tctctatcct tgtcagctct gtgtcgctct
      481 ttgcagtaca gcagtttgtt ggactgacca atcgtttaaa tgcgacttct aattactcag
      541 aatattcaat cagtgtcgct gttttagcag atagtgatat cgaaaatgtt acgcaactga
      601 cgagtgtgac agcaccgact gggactgata atgaaaatat tcaaaaacta ctagctgata
      661 ttaagtcaag tcagaatacc gatttgacgg tcgaccagag ttcgtcttac ttggcagctt
      721 acaagagttt gattgcaggg gagactaagg ccattgtctt aaatagtgtc tttgaaaata
      781 tcatcgagtc agagtatcca gactacgcat cgaagataaa aaagatttat accaagggat
      841 tcactaaaaa agtagaagct cctaagacgt ctaagaatca gtctttcaat atctatgtta
      901 gtggaattga cacctatggc cctattagtt cggtgtcgcg atcagatgtc aatatcctga
      961 tgactgtcaa tcgagatacc aagaaaatcc tcttgaccac aacgccacgt gatgcctatg
     1021 taccaatcgc agatggtgga aataatcaaa aagataaatt aacccatgcg ggcatttatg
     1081 gagttgattc gtccattcac accttagaaa atctctatgg agtggatatc aattactatg
     1141 tgcgattgaa cttcacttct ttcttgaaaa tgattgactt attgggaggg gtagatgttc
     1201 ataatgatca agagttttca gctctacatg ggaagttcca tttcccagta gggaatgtcc
     1261 atctagactc tgagcaggct ctaggttttg tacgtgaacg ctactcacta gccgatggag
     1321 accgtgaccg tggtcgcaac caacaaaagg tgattgtggc tatccttcaa aaattaacgt
     1381 caaccgaagc actgaaaaat tatagtacga tcattaatag cttgcaagat tctatccaaa
     1441 caaatatgcc acttgagact atgataaatt tggtcaatgc tcagttagaa agtggaggga
     1501 attataaagt aaattctcaa gatttaaaag ggacaggtcg gacggatctt ccttcttatg
     1561 caatgccaga cagtaacctc tatgtgttgg aaatagatga tagtagttta gctgtagtta
     1621 aagcagctat acaggatgtg atggagggta gatgaaatga tagacatcca ttcgcatatc
     1681 gtttttgatg tagatgacgg tcccaagtca agagaggaaa gcaaggctct cttggcagaa
     1741 tcctacaggc aaggggtacg aatcattgtc tctacctctc accgtcgcaa gggcatgttt
     1801 gaaactccgg aagagaagat agcagaaaac tttcttcagg ttcgggaaat agctaaggaa
     1861 gtggcgagtg acttggtcat tgcttatggc gcagagatat actatactct ggatgctcta
     1921 gaaaagctag aaaaaaaaga aattcctacc cttaatgata gtcgttatgc tttgattgag
     1981 tttagcatgc atacttccta tcgtcagatt catacgggat tgagcaatat tttgatgttg
     2041 ggaatcacgc cagtaattgc tcatattgaa cggtatgatg ctttagagaa taacgaaaaa
     2101 cgtgttcgtg aactgattga tatgggatgc tatactcaga taaatagtta tcatgtttta
     2161 aaacctaagt tctttggtga aaaatataaa ttcatgaaaa agagagctcg gtattttttg
     2221 gaacgtgatt tagttcatgt agttgcaagt gacatgcaca atttagacag tagacctcca
     2281 tatatgcaac aggcatatga tatcattgct aagaaatatg gagcgaaaaa agcgaaagaa
     2341 ctttttgtag ataatcccag aaaaattata atggatcaat taatttagga gaaaatatgg
     2401 agaaacaaaa cactttggaa atcgatgtat tgcaactatt cagatcttta tggaaaagaa
     2461 agttggtcat tttattagtg gcaattataa cttcttcagt tgcttttgcc tacagtactt
     2521 ttgttatcaa acctgagttt actagtacga ctcggattta tgtagttagc cgtgatcagg
     2581 gagagaagtc tggtttaacc aatcaagact tgcaggcagg atcgtacttg actaaagact
     2641 atcgtgaaat tatcctatcg caggatgttt tggaggaagt tgtttctgat ttgaaactag
     2701 atttgacgcc aaaaggtttg gctaataaaa ttaaagtggc agtaccagtt gatacccgta
     2761 tcgtgtctat ttcggttaat gatcaagttc ctgaaggggc aagccgtatc gctaactctt
     2821 tgagagaagt ggcggctcaa aaaattatca gtattactcg tgtttctgat gtgacaacac
     2881 tggaggaggc aagaccagcg atatcaccgt cttcgccaaa tattaaactc aatacactaa
     2941 ttggtttttt ggtaggattg attgtcataa atgttacagt tcttcttctt gaacttttgg
     3001 acacacgagt gaaacgtccg gaagatatcg aagatgcact acagatgaca cttttggggg
     3061 ttgtaccaaa cttggataag ttgaaatagg agagagagat gccgacatta gaaatagtac
     3121 aaaaaaaact ggagttcatt aagaagacag aggaatatta caatgccttg tgtacaaaca
     3181 tacagttgag cggagataaa ctaaaagtga tttccgttac ttctgttaac cctggagaag
     3241 ggaaaacaac tacttctata aatatagcat ggtcttttgc gcgtgcagga tataaaactc
     3301 ttttgataga tggcgatatc cgaaattcgg tgatgtcagg agtttttaaa tctcgtgaaa
     3361 aaattacagg cttaacagaa tttttatctg gtacaactga tttatctcac ggtttatgtg
     3421 atacaaatat tgaaaattta tttgtagttc aatcgggagc tgtatcacca aaccctacag
     3481 ccttgttaca aagtaaaaat tttaatgata tgattgaaac cttgcgtaaa tattttgatt
     3541 atatcattgt tgatacagca cctattggag ttgttattga ttcggcaatt atcactcaaa
     3601 agtgtgatgc gtctatcttg gtaacggcaa cgggtgaggt gaataaacgt gatgtcccaa
     3661 aagcgaaaca acaattagaa caaacaggga aactattttt aggtgtcgtt ctcaataaat
     3721 ttaatgttca acatgaaaaa tatggttctt acggtaatta tggtaaaaga taaaatgaat
     3781 atagtatgga aggggctaca atataactct ggcattctga actgcacccc aaaagttaga
     3841 cagaaaaaat ctaacttttg ggggtcagta cattcttaca gggtacactt gttagtttat
     3901 tagcttagat actgattgca atttcagaaa ccgatatttt ttcaaataaa tattcggtct
     3961 gtttggaagt gcaatcgaac tgaactttcc aatgctttat tgggcatcat atattaccga
     4021 aacaaataaa ttttgttata ttggatgatg ttgttatgtt attgtaaaaa tattgtgtga
     4081 ccaaatatat tgagtctttg tggtctaata ggctgatata tttaatttga taaataaaaa
     4141 taagatgaag tttgaattta gagtgagaga tagtttatgt atagtatatt aaaacggtta
     4201 ggagatatat ctatatcttt aatagttata acgttatttt gtccattttt tatcctaatt
     4261 gcaattgcga ttaagtttga ttcaaaagga cctgtaatat ttaaacaaaa acgttttgga
     4321 attcacaaaa aaacttttta tgtttttaaa tttcggacta tgaaagtgga gacaccaaaa
     4381 aatgtggcaa ctcgagattt acaaaatcca gagcagtgga tcactagagt gggaactttc
     4441 ttaaggaaaa catctctaga tgaattgcct caattatgta atattcttgt tggtgatatg
     4501 agtattgtag gaccaagacc tgccctttgg aatcaatttg atttgattga agaaagagac
     4561 aaatatggag caaatgatat tttacctggt ttaacaggtt gggcacaaat caatggtcgt
     4621 gataatctat caatagatat gaaagctgaa ttggatggat actatgtgac acataaatcg
     4681 ttgctaatgg acattagatg tatagtaaga acaatacctt atgtgctgaa acgcaaagga
     4741 attgtagagg gaagtcaaaa agagagttaa gttgtacgat gaaaatttta tttgttagtc
     4801 aacattatag accagaacct tttagattat cagatatttg tgaggatctt gttgagagag
     4861 gtcatgaagt tactgttttg acaggaattc ctaattatcc tgaaggtaaa acatatgcgg
     4921 attatcggaa taacaaaaat agacgagaga ctatagaagg agttactgtt tttcgttcct
     4981 atacaattcc aaggggaaaa agtactttac ataggatatt aaattatttt agttttgcta
     5041 tcagttcctc gataggggtt ctactgggac agtataaagc aaaagatgga tcagaatttg
     5101 attgtatttt tgtaaatcaa tcgtctccag ttatgatggc atgggctgct atggcttata
     5161 aaaataaata taagaaacct atgtttctgt attgtatgga tgtttggcca gatagtttaa
     5221 ctgtaggtgg agtgaaacaa gatggcttga ttttcaagtt gtttaaattt atatcgaaaa
     5281 aagtttatcg agctagtgat tatatatttg ttactagtcc atcatttaag aattattttg
     5341 tgaaccaatt tgacataaca gaacaaaaga ttacttattt gccacaatat gcagaagatc
     5401 tttttatccc tgatgaatct agagttaata aagaaagtgt tgacctaact tttgctggta
     5461 atattggcaa agcacaaaat ttggaaacta ttttgaaagc tgccagtttg atagagaaga
     5521 ataccgatct acccaagaaa attcaatttc attttgttgg agatggtacg gaattgctaa
     5581 gtatgaaagc attagctcat gaattggagt taaagaatgt ttccttctat ggaagacgtt
     5641 ctttggaaga aatgcctacc ttctataaaa aatcagatgc tatgttagtt tctttaatag
     5701 gagactcgat agtttctcgt actatacctg ggaaggtaca atcttacatg gcggcaggga
     5761 aaccaattat aggtgcaatt tcaggagata ctaaaacaat tgtagaagaa gcaaagtgtg
     5821 gttttgtcag tcctgaacaa gatgtggaac aattggcaca aaatatttgt aaatttagta
     5881 tgttgtctac ggaagaacaa agagagttag gaaagcaagc tcgttgttac tatgggaagc
     5941 acttttctaa agagcagttt atgacacagt tagaaaatta tttgagagag ggattttcct
     6001 catgagaatt ttaatgatta atactgtttg tggtattagg agtatagata ctttgttaaa
     6061 gaaatttgct gagatttggc gtttcaattt ataggatttg aaagtttagt aagtaaattt
     6121 aagtattttc tgtaagataa taagttctta atgacttatt aactattgta taatagctgt
     6181 aattccaaat aaaagtacat aggtactgac atgttgacga tagtaaggag gaggaatgga
     6241 atcccgaaag aaatttgttt gttttcccaa tagtagtttg cgtttttata ttttgcaggc
     6301 agcgattgcc ttatctattt tatcgcaggc tccctatatc tggaagttta gtgggatacc
     6361 tacacaactt ctgattatgc ctttgtggat cctgttggga gtagtgtcta ttttttctag
     6421 aattgacatg gaacgatcat tcctattttt tttattaaca ataggttgtt taattagcac
     6481 tattgctttg ttagatatag ttacgggagt atcttatgtc tttaatggtt tgtctcagca
     6541 actctatttg gctgtgggaa ttctagtttt aggctactgg aatgctgatg tgattgttca
     6601 ttattggaaa atcatcacca tgactttttt gggagcatgt ttgctgattt cagtggatat
     6661 ttattttcac tactttcaag gacatacttt ttcaaatatt gattatgttt atcgagctaa
     6721 gaattcagcg gcatctatct ttttatcggc agttattctc aacttgtctc tatataatcg
     6781 caagtgggca ctgtggagaa aagtattgtt attagctagt agcggattgc tgatttacat
     6841 gtgcatcctt atgcggtcac gagcagttct gttagcagct gcagtacttc cgctagttta
     6901 tatatggttt caggagacgt ctttggggca taagattgga cggacattag gagtttcaac
     6961 agtagtaggt gcgtttttgc tcaattcagc tatttatgat ttttttatca ataatctatt
     7021 tttaagggtc acatctgaat atcgaccatc tagtctgact ttggactacg tttcctccaa
     7081 ccgttttgtg tattttgaga tctttgctaa agaaatttca ggacatgaat taacagggat
     7141 tggttattat tatatggata atttttttct agagagtttt ctcaattatg gttatatagt
     7201 agggactgct tttgttttaa tagccttgtc tcccatgatt tatgccctct tgcaacgttc
     7261 ttcttctcat cgtttccgca tgcttttttt agcccttgct ttttcttata ctgtcaatgc
     7321 cttatttgaa ggttacgcgc catttggtcc tggtgccaag agttttattc tttggttagt
     7381 ttttggttgc cttctgaata cacgaattgg aaaggttggt gaacattctg aaacaagtta
     7441 gtctaaagtg gaactatgtg tttaatcttg ccaataaact attttctcta actattccac
     7501 ttattgttac tccctatgtc actcgagtct tttcttcaga tcattttggg atttatactt
     7561 ataccaatac agttgcttct tactttgtta cctttacatt gatggggata agtatgtatg
     7621 gaagtaagaa aatttctctt aaaagacatg atgagatagc agtcaatgat gaatatgctt
     7681 ccttactgac tgtccagctg cttaatgtag gtctagccac gttaacttac tttctctatg
     7741 tgaccttttt tgtcaataat aatcaagtta tttattggat ccagatgttg tatgtgattt
     7801 ctgctggttt tgatatgact tggtttttat caggattgga acgttttcgt gaaattgctg
     7861 ttcgaaatat cattgtaaat gtcttatcag ccctcatgat ttttttcttt gtgcatacgg
     7921 aggctgattt ggctatctat accttaataa aggtagggac gatttttatc agtcagattg
     7981 ttattttttt accagttgtt cggatgcaac ggttttatct tgcaggagct gaacatattc
     8041 gacgtaccta tcgaggcttg cttttgttgt ttatccctgt tttggcagac accctttttc
     8101 aaactatgga taagatcatg ctaggtatct atgcatccta tactgctgtg ggtttgtatt
     8161 actcaagtag gatggttact gacatcccgc aaactgtcat tacttctctc aatataatct
     8221 tatttccacg aataacacat cttttaagtc agaataaaaa agttgaatct aataaacttt
     8281 tttatcagtc ttttatctta attattgctt tatctctagc tacagctttt ggagttagtg
     8341 ctattgctag ggattttgta ggtatttttt ttggatcttc atatggtgcg gtagcagatt
     8401 atgtgcctag tttatcgctc tatatctgcc ttgctgcctg gagtggaacg atacgttacc
     8461 aatatctgat tcctcattca cttgagagag tctatgtagt agcgattatt ttgggaagtg
     8521 ggatcaatct agttttaaac tctctcttaa ttcctttttt gggagtatac ggttccattt
     8581 tagctactat tatatcagaa ttagtgattt gtgtttacca gacatatcct attcgaaagg
     8641 aaattcctct taaaggattg ttaggatatg tgatcatttt tgcaggcttg tcttttctta
     8701 tgtatctatc tcttggttgg ctacgattgt tattgctagg ccgcctatcc acagtattgc
     8761 tattggcaag tgaaataata tttggtatcc ttgtttttac tatcgcaact ataacctata
     8821 tttatctagg taacccaatt ttatggcaag ctattaaaaa atatatagaa agtaggaaaa
     8881 acgtatgatc tctatcatta tgccagctta taatgaagaa aaaaatatcg gagcagctat
     8941 tgccagtatt caacagcaaa cctatacgga ctttcagttg attatcgtca atgatggatc
     9001 tacagatgat acggcagcta ttgtacagga aaaaatcatg ggagatgagc gaattgtctt
     9061 tttgaatcct ggaaagattg gcaaggtacc agcttataac ttggcttcac agtatgtaaa
     9121 aggagactgg atatatttta tgggagcgga tgaccagttg ccattggatg cctttgaaaa
     9181 gtggaacaag gaggctcaaa agtggaatcc tgctgaaaag gtggctttaa gagctcgcat
     9241 gcggatggtt tctgactctc acaagtatga tggattggta ttaccaaaga aaaatacagt
     9301 tcgcaatttt agtggacctc ttaccttgct ttcaaaagag atgcaccgtt ttatccttcc
     9361 tatacctgag gcctatccga acgaagatat ttggtggggg ctatgtattg agtatttcgg
     9421 agatcgtgtt tcgttgattg aggatgttgt ggtttattat cgtgttcatg aggggaattc
     9481 tatatcccga acctcaactt ttgaaccttt taacgagaaa tatcatatcc gtcagattat
     9541 ccgtcgtgat tttttagaga gatttagcaa tcacttaaca gcagaccaga agactaaact
     9601 tcagcgtgaa ttgaaactag aagaagcacg ctataaagga aatagattgc caattcttct
     9661 gatgccaggt atttctgcag tacacagact tcgattactt tttttatcgg gtaggcgttc
     9721 atatgtactt aaagtcaaat tggatcgctt tttcttagga cattagaaag aaggaagaga
     9781 tgtcaaagaa aaaaatttct tatgttacaa ataatattgc tccttttagg gttatgttat
     9841 tagatgagtt agccaagcat gcagaagtga ctctttttta tgtgcacgaa attgaggcgg
     9901 gggtaaaggc tgagtatgtc aagctacgac ctgttcgtac caagctccaa tcaatcacag
     9961 aactaggttt atttcagacg tttcaaatgt tgaaagagat ggatatggtc ttctttgatg
    10021 gctatactgg gtgggaaaag atgttcttga tgagcagtat gtggctaaca agacggcagt
    10081 acgctatttc tgttgatggt ataataaatc atagtaatat ctcacttaag cagagactgt
    10141 tggattttat taagtctgtt gctctaagca aagcggagtt tgtgcttagc accaataccc
    10201 caacagatgc ttatatacag caattagctc ccaaggcaaa gattaaacga cacatatttt
    10261 caactctttc acaagatgat ttcaaaaaca tgatagaggt tgcctcggat acggttttca
    10321 caagatatag tattcgaaaa tctgagaaaa atctgctttt tgtgggacag tttatcaata
    10381 gaaaaggagt cgatgagctt ttggctttta tgaaagagca cgaagctgat acttcgttgc
    10441 agttaattat ggtcggaggt acaagagaag aattgtcagt ttttgaaaca gagattcctt
    10501 ctaatataca tataattcct tttctagaaa aaactgatat cctagagttg atgcgggtgg
    10561 cagatgtctt tgttttgccc actcgagaag atatttgggg actggttatt atagaggcgc
    10621 tatcaatggg cattcctatt gtttctacgg atcgttgtaa cgcagccttg gagtttgtta
    10681 gggatggcga aaatggttat ctgatgcagg aagtgactgc ggtagaattg gctaacaagc
    10741 ttaaggctac ctttaaacta gatgctgagc atgttgctcg ctatgatcaa aaactgatgc
    10801 aagactataa tctggaaggt tcagcaaaaa atattatgga catcttggag ggaagtcatg
    10861 tttaattcat cttgtgcttt atttattgtt agttgcgaga ctaatcagca ggtagtcaat
    10921 ctcctcatcc agtccatgcg tcagcagatt tctcatatgg tatccattta tgtatcatca
    10981 gatggcccat tgttaatcac ggatcctagc gtaagggttt tgattggtca ggaagaagtt
    11041 tttggagatc gtgttgcaac tgctttggaa caagttactg aagagcgagt cattgttttt
    11101 tgtgatgact ttatcgtaga aaaaccagct aaaattgaag aattagaaga actactgtct
    11161 ctaatggaag aggatacaag tattgctagt attgccctgt cacaaatatc tggagggaat
    11221 acacctgagc gtattgctga gcattatata agacgcacga aatatgcccc ctataagaca
    11281 actcttcaat gcgctatttg gaagaagtct agtttgattc aattcatgaa ggggagtccc
    11341 tctccttggg aatttgagat ttatcataac tttaaaactt acctgacgaa agagaaattt
    11401 tatgctttag aggatgatat gttccaacct atcccttata atagaggaaa gttgattatt
    11461 cgaggtaaag ttgttaaacc tgaaaaagaa cgtttggagg aacttttggg ttattcatta
    11521 gatttatcgg atttcccaga aacggagtct tttgtccagg gggaaaatct tactgtaggc
    11581 tatcggttga agagaaagat taaattgtta gaaaaagaaa ttatttatcg tttgaaatct
    11641 aaaataaaga ataagaaaaa atagtgaaaa agaaagttta taatatttgg tggatgcaaa
    11701 agatttaaag attgagttat ctttatttct acacctttaa aaatatagct tttcttttgg
    11761 ataaggtgta tgttgaaatt ctcaccaata ttatcagtca gaaaaatatt gtagtgcgtt
    11821 atttttcatg ttgttaagct ttaaatttat ttaaaaagca ttatgttgaa catcattata
    11881 gataggagta ataactatgt ttacaaagaa aactctcctt attacagggg ggacaggttc
    11941 attcgggaat gcagttctca aacgattttt gggaacagat atttcggagg tacgtatctt
    12001 ttcaagagat gagaagaaac aggatgatat gcgtcatgaa tttcaagcaa aaatgccaga
    12061 agtagctgat aagatacgtt tttacttagg agatgtgcgt gatttagctt ctgttaaaaa
    12121 tgctatgatc ggtgtggatt acgtatttca tgctgctgca ttaaaacaag tcccttcttg
    12181 tgaatttttc cctgtggaag cagtcaaaac taacgttcta ggaactgaaa atattctcac
    12241 tgcagctata gaagctggag taaaacaagt catctgcctt tctacagata aggcagccta
    12301 tcctgttaat gcgatgggaa cctctaaggc tatgatggaa aagattgctg ttgctaagtc
    12361 aaggacggta gaagaagatc agacaaaagt ctgtgtaact cgctacggca atgttctatg
    12421 tagtcgtggt tctgtgattc ccctatggat tgatcaaata aagcaaggga atcctataac
    12481 gattacggaa cctagtatga ctcgttttat tatgtcctta gaagaagcgg tagacctagt
    12541 tctgtttgct tttgaaaaag gaaaaacagg agatatccta gtacagaaag caccagcatg
    12601 taccattgaa gtgttggcgc aagctgttac ggaacttttt gcacctaatc aagatattaa
    12661 agtaatcggg attcgccacg gtgaaaagat gtatgaaacg ttgttgacta ctgaagaatg
    12721 tacgaatgcc attgatttag gcggctttta tcgtgtgcct agcgataatc gagatcttaa
    12781 ctatgataag tatttcaacg aaggggatgc caaacgcaat cccttaatag agtttaacag
    12841 tagtaataca gaactctgga atgtcgagca ggttaaggaa aaactcttac ttttgcccta
    12901 tattagggaa gaattagcat ctttaaatca gtgaggtatc ctatgaaaat agcagtagca
    12961 gggacaggtt atgtgggttt atctattgca attctattag cgcaatatca taaggttata
    13021 gcggtagatg ttattcctga aaaagtagag cttatcaatc gtcgccaatc tcccattaag
    13081 gatgatgata ttgaaactta tttagtggaa aaggaattag acttagttgc aacattagat
    13141 ggtaatgaag cttatcgaga tgctgacttt gtcataattg ctgtcccaac taactatgac
    13201 agtaaaaaaa attattttga tacatctgtt gtggaagcag ttattgagca gattattgcg
    13261 gttaatttga aggcaacaat tgtcataaaa tccacaattc ctgtgggata tacagaaagt
    13321 ctccgaacac gttttgggca atttaagatt ctctttagtc ctgaattttt acgggagtct
    13381 aaagcacttt atgataatct ctatcctagt cgaatcatcg ttggagcaga tttgagagat
    13441 acggagcagg tagttcaggc tgagcggttt gcaactcttt tgcaggaagg ttcacttaaa
    13501 cctgatgttg agaccttaat tatgggtgta acagaggcag aagcagtcaa actatttgcc
    13561 aacacctatt tggctttgcg ggtttcttac tttaacgaat tggataccta tgcggagata
    13621 aagggattgg acactaaatc catcattgac ggagtagggt tagatccacg aattggtagc
    13681 cattataaca atccgtcatt tggttatgga ggttattgtc ttcccaaaga tagtaagcag
    13741 ttgctggcga attatcatga tgtaccacaa aatatgatga cagctattgt agaaagtaac
    13801 cgtactcgca agtattttat tgccgatcgt attttgaaaa atgcgttgga gctttcagac
    13861 ggtaatcaaa caatcatagt aggtgtttac cgcttaacta tgaagagtgg ttcggataat
    13921 ttccgtcaat catcaatcca aggtgttata aaatgtttaa aggccaaagg tgtagaagta
    13981 attatctatg aaccaacttt ggaggatcat agctttttct ttggtaatca ggtggttaat
    14041 gatttggaag tttttaagtc tagcagtcaa gtgattgttg ccaatcggat ggaaaaatct
    14101 ttatatgatg tgctagaaaa agtttataca agagatattt ttcagcgaga ttaagtatat
    14161 ggagggaaaa atatgccatt aaaaatttta gtgactggtt ctaaaggatt tgtaggaaaa
    14221 aatcttatct gtactctgga agctttgaaa gatggacgag ataggactcg tcctaattta
    14281 gagattggag agatttttca gtatgatcgt gatacagatc cgattttatt agatgaatat
    14341 tgtaagaagg ccgatttcgt attccattta gctggtgtca atcgtccaca gaatcctgat
    14401 gaattcatgg agggaaatta cggtttttca agtagattat tggagatttt agaaaagtat
    14461 gaaaacactt gtcctgttct actctcaagt tctactcaag ctagtttaga aggccgattt
    14521 tcaaactcta tatatggaca atctaagcta gtaggggaag aactcttctt tgaatatgga
    14581 aagaaaacgg gagcacctgt cttagtttac cgtttcccga atctttatgg gaagtggtgc
    14641 cgtcctaact acaattctgc tgtagcaact ttctgtcata atctagctca cgatttacct
    14701 attcaagtaa atgatccaag tgtagaattg gagttgctgt atattgatga tttgatacaa
    14761 gagtgtctaa ctgcattgga aggaaatcct catcgttgta atctagatgg attacaaatc
    14821 ttacctagcc catcaggaaa ctactgctac gtaccaacga ctcatcgtgc aaccttagga
    14881 gagattgtct ctctattaga aacatttaaa aaacagccta atagtttagt tatgcctgaa
    14941 attcctcaag gatcgtttaa aaagaaattg tattctacct acctatctta tttaccagta
    15001 gataagttta agtttcctct aaaaatgaat atagatgaac gaggtagttt tacggaatta
    15061 ttaaaaacag aaaataaggg tcaattttct gttaatattt ctaaacctgg cattaccaaa
    15121 gggcaacatt ggcatcattc taagtgggaa tttttcatgg ttgtttctgg tcgtgcttta
    15181 atacaagagc gtaggatagg gctggatgaa aacggtcaag agtatcctat tctgaacttt
    15241 gaagtgtcgg gcgataagat tgaagcaata catatgatac cgggctatgc acataatatt
    15301 attaatcttt ctgatacaga aaatctagtt actgtcatgt gggctaatga gtcatttgat
    15361 cctagacatc cagatacttt ttttgaacaa gtggagaaat aaatgaaaat taagacagat
    15421 tatagtgata ttcactttaa agataatggc aaacttaagt tattgattat tgtgggaaca
    15481 cgtccagaga ttatacgtct aagtagtgtt atcactaaat gtcgaaagta ttttgatgtt
    15541 attttggcac atactggaca aaactatgat tacaatttaa atggtatttt ctttgataat
    15601 ttagggttag acactccgga cgtatacatg gatgctgttg gagatgatct tggtgctact
    15661 gtagggaata ttattaatac ttcatacaaa ttgatgaatc aaattaaacc agatgcttta
    15721 ttgattttag gggatacaaa ttcttgttta tcagctattg ctgccaagcg tttacatatt
    15781 ccaatttttc atatggaggc tggcaatcgc tgtaaggatg agtgcctgcc ggaagagact
    15841 aatcgtcgga ttgttgatat tatttcagat gttaacttag catactctga acatgcacgt
    15901 aagtatttac atgagtgtgg tttacctaaa gagcgcacat atgtaacagg ttctcctatg
    15961 gcagaagtgt tacataaaaa tttatctgcc attgagtctt cagatatcca tgaacgtttg
    16021 ggattgaaaa aaggaggtta tatcttactt tcagctcacc gtgaggaaaa tattgataca
    16081 gataaaaatt ttatttctct ctttacagca attaatcaat tagctgaaaa gtataatatg
    16141 ccaatcttat attcttgcca tcctagatca aagaaaaggc tacaagagag cggttttaaa
    16201 ctagataaac gtgtgattca gcatgagcca ctaggattcc atgactataa ttgtttacag
    16261 atgaatgcat ttgttgtagt atctgattcg ggaactttac cggaagaaag tagtttcttt
    16321 actagtcaag gttatccttt tcctgctgta tgtattcgta caagtacaga acgtcctgag
    16381 tccttagata aggcaggatt tattttggca ggcattgatg aaaattctct tcttcaagca
    16441 gttgaaactg ctgttagctt ggcagaagat gaggattttg gattaccggt tccagattat
    16501 gttgaggaaa atgtctctac taaagttgtt aagataatac agagctatac agggatagtg
    16561 gataaaatag tttggaggaa aagctgaatt gtatattttt aataaatcaa aacgagatga
    16621 ttaattctta gtagaacaag agtaaaattg aacgtatttg atggaaatgt cttacttgat
    16681 agtcgaggga tagccattct atcggatttt tggcttgttt ttgcgcttca tgtttgatag
    16741 aataaagggc tctttgtcaa ctgtagtggg ttgaagaaaa gctaagcttg agaaaggaca
    16801 aatttcgtcc tttctttttt gatgttcaga gcgatgaaaa tccgtttttt gaagttttca
    16861 aagttccgaa aaccaaaggc attgcgcttg ataag
//
LOCUS       DAVHSL010000047        16207 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000047 DAVHSL010000000
VERSION     DAVHSL010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.049"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..816)
                     /locus_tag="VVR39_001632"
     CDS             complement(<1..816)
                     /locus_tag="VVR39_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6031066.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDL"
     gene            complement(893..1189)
                     /locus_tag="VVR39_001633"
     CDS             complement(893..1189)
                     /locus_tag="VVR39_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6031067.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(1509..2408)
                     /locus_tag="VVR39_001634"
     CDS             complement(1509..2408)
                     /locus_tag="VVR39_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031068.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILGEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(2480..3040)
                     /gene="rnmV"
                     /locus_tag="VVR39_001635"
     CDS             complement(2480..3040)
                     /gene="rnmV"
                     /locus_tag="VVR39_001635"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU6031069.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(3040..3813)
                     /locus_tag="VVR39_001636"
     CDS             complement(3040..3813)
                     /locus_tag="VVR39_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU6031070.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(4119..4784)
                     /locus_tag="VVR39_001637"
     CDS             complement(4119..4784)
                     /locus_tag="VVR39_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU6031071.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKNKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            complement(5047..5181)
                     /gene="rpmH"
                     /locus_tag="VVR39_001638"
     CDS             complement(5047..5181)
                     /gene="rpmH"
                     /locus_tag="VVR39_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU6031072.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(5326..6540)
                     /locus_tag="VVR39_001639"
     CDS             complement(5326..6540)
                     /locus_tag="VVR39_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6031073.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(6696..6989)
                     /locus_tag="VVR39_001640"
     CDS             complement(6696..6989)
                     /locus_tag="VVR39_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031074.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            7151..7603
                     /locus_tag="VVR39_001641"
     CDS             7151..7603
                     /locus_tag="VVR39_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU6031075.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(7638..9026)
                     /locus_tag="VVR39_001642"
     CDS             complement(7638..9026)
                     /locus_tag="VVR39_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6031076.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            9092..10054
                     /locus_tag="VVR39_001643"
     CDS             9092..10054
                     /locus_tag="VVR39_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU6031077.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(10083..10421)
                     /locus_tag="VVR39_001644"
     CDS             complement(10083..10421)
                     /locus_tag="VVR39_001644"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031078.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSSKHCFEVADETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDE
                     VSNHTYGKAT"
     gene            complement(10485..11495)
                     /gene="ccpA"
                     /locus_tag="VVR39_001645"
     CDS             complement(10485..11495)
                     /gene="ccpA"
                     /locus_tag="VVR39_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU6031079.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(11920..12519)
                     /locus_tag="VVR39_001646"
     CDS             complement(11920..12519)
                     /locus_tag="VVR39_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6031080.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKVGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(12521..13618)
                     /locus_tag="VVR39_001647"
     CDS             complement(12521..13618)
                     /locus_tag="VVR39_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6031081.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNVIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(13618..14355)
                     /locus_tag="VVR39_001648"
     CDS             complement(13618..14355)
                     /locus_tag="VVR39_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6031082.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(14357..15241)
                     /locus_tag="VVR39_001649"
     CDS             complement(14357..15241)
                     /locus_tag="VVR39_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031083.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(15228..15422)
                     /locus_tag="VVR39_001650"
     CDS             complement(15228..15422)
                     /locus_tag="VVR39_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031084.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(15419..15625)
                     /locus_tag="VVR39_001651"
     CDS             complement(15419..15625)
                     /locus_tag="VVR39_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031085.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         4846 a         3724 c         2835 g         4802 t
ORIGIN      
        1 tagatccacc agactatttt cctgtaaacc aagtagatag acgacactta gtaaggtaga
       61 aatccctgcc aaggtcaatc cataaagtag aagagcaatg atgaccagtt gcaccgttgc
      121 cataaacaag gcaccttgat accagagaat ccccaatccc aaaagactgg ataccagcac
      181 tgagcagata agctgtctca catcttctaa cactggtctg agagcaactc caaacaagct
      241 ctcaccagct attaagcgaa tccctgcctg acgaagggat ttgatccgat aaatcagggt
      301 cagactcata aaggtcagca gaaaaatagc taaactcagt agcaccatag gggtggccgt
      361 caatagtaag actatcgaaa atggatcttc tccattcgaa acaaagcctt gataaccaag
      421 ctctttcaag gtggtctgta agctcactcc atccaaactt cctgacacaa tcaagtaaga
      481 ccctaataaa tcactcgttt ctgcactctc cttggaggaa atggtcagac cttctggaag
      541 ctttccctca ccataagtgg cataggtaaa gcgtgtttct ccagcttcat ttggctcaac
      601 gattcgacga gcaatgagac tattgtgctc taccgccaag tgactcaaag cctctgtcac
      661 ctcttcccga ctagctactg gttgatttat catcattcct gtcacatcaa cagaaggata
      721 gttaccaaat aaaatctctt ctcgatggtc aacggaagtt atcaccatat aaagcgatac
      781 caataccatt gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa agttacttgg
      841 tcacttagtg agaaggtgac caagtaaagc taaacaatag ggctatacca ttctaaacat
      901 tatagtagaa tgcaactttc tctccccaag aagtacgaat ccatgcacga gaagtccctc
      961 cagcaccagc atatcccttg tcagatgaac cagtttttct gctaacaact gttgaactat
     1021 ggtattttga agggtgatag tagtttgagt aagcaccacc gttacctgaa ccataagtcc
     1081 aaacaccacc ttctgggtat tgaacggctg cagaggcaac tgctacactt ccacctaatg
     1141 ttgctgcaat gctcgctaca agagctaatt ttttaactgt ttgtttcata ttgatactcc
     1201 tctatttttg attacaagat tgttgagtta cttgctcctc tttccattat caacgttgat
     1261 actattatat taccaaatga tattctaaaa ttatttgttt ttctctaaat tgtcaaaata
     1321 gcaccctgaa atgaactttt atagtcatta tactccatct ttatcacact atcaaggaca
     1381 tcaatgtcct taaaatctaa ctatttcata ttatttttag cttatatcta aaaaaacagt
     1441 tctaaagacg aactttagaa ctgttttgat acgaggacaa ggacattttt gtcactgatt
     1501 cactatgttt ataaatattt tttgacatcc tcttgccatt cctctgtcaa tttctttact
     1561 agaaatccat ctccaattag cttcgcaaat gttttagaag actgataaaa tgattcagct
     1621 aaactaaaat ctctttctac tcttaatgct tgcttccaca aaaacataaa tacaagaggt
     1681 ttcttttgat aatcttgagt tttatccata atttcttgta aacacgatag ataatcatta
     1741 aaacaatcag ttactcctac cttttcaaga caacacattc ctgaaataag agtatctcta
     1801 attataaaga agttttctaa tttagttacc tttttctgtt ccaaaagaaa gagcattagc
     1861 ttttcgattt gatttataaa tttggcaaga tcttttctaa tgagcatttg ataaaaaaac
     1921 aaacgaatca acaacatatc atttgttgaa taaacttctt tttctatgat ctgaggcata
     1981 tgttccccaa gtattaactc tgcatattca ggccttctag ttctagaagt atccaaacac
     2041 gcctgcaata cttcacatgc taattgttct tctttaggaa gattatcaaa gtatgtttta
     2101 taaatctctt ccaaacacgc ttccttctta tcgtactcct cttctttacc atagattggt
     2161 tcacgtaaaa tctggtattt caattctaaa taagcaggag gaagagctga aaaatccggc
     2221 ataaggctat aaactggaac tcctagccgg cgagcaatat agtctaactt gggcaaactc
     2281 ggttgcgaag ctccactttc aattcgcgac agttgacgaa ctgtcagttc ttgctcatct
     2341 ccacaaaaat ctggacgact aattcctttt tctatccgaa tctctttaat tttttgacca
     2401 attaacatca gacgcctcct cttctacctg cttcgaaaaa tactgtgaaa cttaaaaaat
     2461 tgtaacggct acatctttcc tactcataag atttcatagc ttcttccact tctgccaaag
     2521 taaccccaaa caactctagg cgtttgagga gttgcttgcc gttagaatag ccgattcgga
     2581 gagtctctcc gagatattct ctacgcttac ggctgtctgc ccctgctaga aaaccaaggc
     2641 gaatcaagtc gctacgacta atgtcaaact gactctcatg ttcaaattgt tctgtcacct
     2701 gagctagagc cgttttcagg tcttcatagc tggcatgctc aattcccaga gaacgcccct
     2761 tggtcttgga cttgggaaca gcttcatctc gcttgagaaa ggcatgctga actgttggaa
     2821 tgaccgtcat gatcatgcgc cgaatccgtt ccccattaaa atctgggtct gtaaagacaa
     2881 tgactccatg acgttggtgc aggcgctgaa tccgctctat atcctgatca ttgatggcag
     2941 aacctcgagt ctcataggtc tccacatcga aataacgttt gagattgacc gtatcatcac
     3001 gcccttcaac cacaattact tgggaaattt tctctttcat tacttgctgt ccaatccaaa
     3061 aatgcgttct gcatttgcag tcgttgccgc cgctagctct tctgtcgtca taccacgcaa
     3121 gtcagcgata aagtcgacca catagcgagt ataggctgtt ttattttcac gaccacgctt
     3181 gggtacaggt gctaagtaag gcgcatctgt ttccaccaac atcttgtcca aaggtaactc
     3241 tttagctgct tcttggaggt cagttgcctt cttgaaagtc accactcctg agaaggaaat
     3301 ggtcatacca agatccacaa acttctctgc ccactcaagc gtccctgaaa atgaatgcat
     3361 gataccacca cgaggaccaa cgccctcact cttgataatc tcataggtat cttccagcgc
     3421 atcacgggta tggacaacaa aaggcaaatc caagtcctta gatagctgaa tctgacggcg
     3481 aaaaacctgc tcctgcacct ctttgggcgc tgtcatccaa tggtagtcta agccaatttc
     3541 acctaaagcc acaaccttgg aatgttttaa cttatccaac aagtaagcct caacttcctc
     3601 tgtataagta ccagcttctg taggatgcca accaatagtc gcatagagct gctcatactc
     3661 atctaccaac tccaaggcat gctcaatcgt cggtttatca aaaccaacaa tattcatctg
     3721 tgtcacaccc atctcatcag ccaaggcaat ttcttctgcc tcacgacctg caaattcttc
     3781 tacattcaag tgtgtatgtg tatcaaaaat catctcttct aacctcgttt tctatccttc
     3841 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
     3901 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
     3961 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
     4021 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
     4081 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
     4141 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
     4201 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
     4261 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
     4321 actggtctct taggaactgt aaccatggca atggcttgca ctccaatcgt ttctgcttcc
     4381 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
     4441 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
     4501 tcctgcttgt tcttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
     4561 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
     4621 gcctggctac caccgccttc attcgcatta gcatctgagc ttccagtatt gcctccctta
     4681 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
     4741 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
     4801 aatgtgattg ttgctgtacc atctccagct acttcaactt tatagtaaaa taaaataata
     4861 acaggacaaa tcgatcagga cagtcaaatc gatttctaaa aatgttttag aaacagaggt
     4921 gtactattct agtttcaatc tactgtaaca tcgcttccga atccatttgc atctactgaa
     4981 cttttttaca aaaataaaaa tcagtagact cgagttccta ctgatttttg atagaattcg
     5041 tttggattat gcagccaaaa ctttgcgtcc tttacgacga cgagctgcca atacgcgacg
     5101 accattttta gttgacatac ggttacggaa tccgtgtttg cgcgcacgac gaagtttact
     5161 tggttgataa gtacgtttca cgatgaatac ctcctcatag attttgtatt cgtttagccg
     5221 gctataaagt gatcagttac taaacatact ttactattct atctgattct ttcacttttg
     5281 tcaatagctc taggcaaatg tttccagctt tttcgaatgc aagccctatc tacgatactg
     5341 tttcaagaaa cgagtcatct tttcttggat ttgggctaac tcatcaacac gaggaaggta
     5401 aacgatacgg aagtggtctg gttcctgcca gttaaagcct cgaccatgaa ccaagagaac
     5461 cttttcctgc ttcaagaaat caaggacaaa ctgctcatca tcatcgatac ggtacatatt
     5521 gcggtcgatt tttgggaaga tatagagccc cgccttgggt ttaacggcag acaaacctgg
     5581 aatatcttga atggcattat agatgaaatt tctttgctcg tagattcgtc caccaggaag
     5641 aagcaattca tcgactgatt ggtgaccccc caaggaagtt tgtacgactt gttgggccaa
     5701 aacgttagag caaaggcgca tattggacag catattgagc ccttcgatat agcccttaac
     5761 atgagtctta gggccagaca agaccatcca acccacacgg aaacctgcta tgcggtggga
     5821 ttttgacaga ccattcatgc tgacacagaa gacatctggt gccaagctcg ccacaggcgt
     5881 atgcacatgt ccgtccatta ccatgcggtc atagatttca tccgcaaaga taatcaaatc
     5941 gttttgacgg gcaatctcaa taatctccag caagagttcc ttaggataaa gggctccagt
     6001 tgggttattt ggattgataa ggacgattgc cttggtattg gaagtgattt ttgacttgat
     6061 atcgtcaata tctgggtacc attcaacagc ttcatcacag atatagtgaa cggcatttcc
     6121 tccagctagg ctgacagccg ccgtccatag aggatagtct ggcattggca ctaagacctc
     6181 atccccattg tccaaaagcc cctgcatgga catgacaatc aactcactga caccatttcc
     6241 aaggtaaata tcatcaatat ctacgtttgg gaatttcttc agctggcaat actgcatgat
     6301 ggccttacgg gctgagaaaa ttcctttgga gtcagaatag ccttcactat cacgcgcatt
     6361 cataatcaag tcatgaatga cctcgtctgg cgctgtaaag ccaaattctg ctggatttcc
     6421 tgtattcaga cgtaaaatct tttctccatt cgctcgcatc cgcatggctt cttccaatac
     6481 aggaccacgg atatcataag caacatgctc taacttacta gacttgttat attctttcat
     6541 cttgtttcct caattcatca ggatagtaac attataccac tagaaagaga atgcgacaag
     6601 tttactgaaa tgtgttacta gtttcgtata gaagaaaaac cttgctaaag gcgaggttaa
     6661 gaacgtagag atagcaggta ttttgcaaag acacatcaca taccaaaaga taaacctaga
     6721 aaaagcaagc ctagaaagga gtcataaaga agattaaaca tgaggaaaag cccccatatc
     6781 atcaagtaat cccaacgccc acttcgtttt gcaactagaa ataagattag atggtagagt
     6841 acatgaaaaa ctaaaaatcc aataaaactt ggataaagaa gcggtaccag actctctaat
     6901 tgacagatca tgatcacttc taccaagact gaaactagga taattccata ataaaggaaa
     6961 tttgattttt gaaaagagtt tttcatcatt ctcccttcct tcacttcttt cctgctatcc
     7021 tttcttttat tttatcatat atttatatag agtttaagcc ctaatattct tttgaaaaat
     7081 actttttttg ctttacttct atagtgaaaa ggtttacaat tatagtaaga aaatttcagg
     7141 aggtttcatt atggcacaac gttaccaaaa tatcatggtc gcaatcgatg gttctaagga
     7201 agcggacttg gcttttgtca agggagttca ttctgctcta cgaaacgacg ctaaactcac
     7261 catcgcacat gtcattgaca cacgcgctct ccaaagcgta tccacctttg atgctgaagt
     7321 ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa gagtacgaaa aacgtgctaa
     7381 agatgctggg gtagcagatg ttcatatcgt cattgaaatg ggaaatccaa agaccctgct
     7441 agcacgtact attccagatg ccgaggaagt ggacctcatc ctcgttggcg caactggtct
     7501 caacgccttt gaacgcctct tggtcggctc ttcatctgaa tacatactcc gccatgctaa
     7561 ggtcgatttg ctggttgtga gagaacaaga aaaaacctta taatcacaaa gaaaaggagc
     7621 ccctagctcc tttttgttta cgatttattt ctctctttat ggcgttcgta agccttgagc
     7681 tggcgctgca gttccttttt aatagcaggt tctggagcat atttttcttc ccaattatct
     7741 ggttttaaga ttttatgggt cactggatca aaatgagcct tgccatctgg aaaaattttc
     7801 cccatattgg cctgatggac aatatcaaaa atacgttctg ggtccacccc catcaagaca
     7861 aaactgccgt aggtgaagta aagcgtgtca atcaaggcat ccacttgccc tatcaaatct
     7921 tgctgagcag gtgtcttctt ggctacttta tctgctgcct tatcaagggc ctgatgaagt
     7981 tgcgatacag cttgaccaaa atcttcttca gaaggactgg ctgctcgaac aaactccacc
     8041 aattcttcta ttttaaaacc agccctatgg gttgcaccct ctaaatccca agctcgaggt
     8101 tcttcttggg ttcgttcatc catcatgtgg tggaaggtct tgaccttatt gaaatgatag
     8161 tcacggctga caaagacttt ttctgaagac aaaacaccaa aatgttccaa ggccttgtgg
     8221 atcccatctt gttgattgct agtggtaatg tgcttggcag cttccttgac actgctacta
     8281 ccatttccca tagcgaccga cataccgacg ccagccagca tttcaaggtc attatctgag
     8341 tcaccaaaag ccatgacttg attgaggtca aagccatatt ctttcccaac tcggcgaatg
     8401 ccttctaatt tagaatttcc ctgattgatg acatccgatg caaaaggatt gctacgtgtc
     8461 aatttcaagt cttcaaaatc agctgccgcc ttctcagatt cttctggtgt catcagcatc
     8521 aaaacttggt agataggctg attcatcagg tgaagcaggt cctcttcctt ttggggaaca
     8581 accttgctga ccatgcgatt aaaagactga ctcaccgtcc gagttaaaac agagggaacg
     8641 aagcgactaa ttcgttggga aaaagaaccc agaccaaagg acatgatttt agaacccaac
     8701 atggcatcct tggtccctag ggcaatctcc gtgccctctt ttttagcata gctaattaga
     8761 tggcgcaaat gtaacttgga aatagggctc gtgaacaaga ctctgtcttt actaaagata
     8821 tactggccat tataggttac cgcaaaatcc agatccaaat cgtccatcaa ttccttaaca
     8881 aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc cttgttcttt gacaatctta
     8941 atcgcatcct tagtagattt caaaacactc ttgcgattgt tgaccaaggt tccatcgata
     9001 tcaaaaaaaa cagctttgac ttccatccta tcccaatctc cccttttgtg atacaatgat
     9061 tataccacat ttcagaaaga gttagtaaat catgcctaag aaaatccttg ttttacatac
     9121 gggtggaact atttccatgc aggccgatgc ttctggcgct gttgtgacga gttcagataa
     9181 tcccatgaac catgtgtcca acccacttga aggaatccaa gtccacgcct tggacttttt
     9241 taaccttcca agtccccata tcaaacccaa acatatgctg gtcctctacc agaaaattaa
     9301 agaggaagca gataactacg atggagtggt gatcacacac ggaaccgata ctttagagga
     9361 aacagcctat ttccttgata ccatggaagt tccccatatg cctatcgttc taacaggagc
     9421 catgcgtagc tccaatgagc tcggtagtga tggtgtttat aattacctaa gtgctttacg
     9481 agtggccagc gatgacaggg ctgctgacaa aggagttttg gtcgttatga acgatgaaat
     9541 ccacgctgcc aagtatgtca ccaaaacaca tacgactaat gtcagcacct tccagactcc
     9601 aacacatggc cccctcggtc tcatcatgaa acaggaaatc ctctacttca aaacagctga
     9661 acctcgtgtt cgctttgacc ttgatcacat acaaggttta gtccctatca tctcggctta
     9721 tgctggtatg acagatgagc tgattgatat gctggattta gaacacttgg acggtttgat
     9781 tatccaagcc ttcggagctg gtaatattcc caaagaaacg gctcaaaaat tagaaagcct
     9841 tctgcaaaaa ggaatcccag tcgctctggt atcacgatgc tttaacggta ttgccgaacc
     9901 tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa gcaggcgttt tctttgttaa
     9961 agaactcaat gcccaaaaag ctcgcttgaa actcctcatc gccctcaatg ccggactaac
    10021 aggacaggct ttgaaagact atatggaagg ctaatactct tcgaaaatct ctgcaaacca
    10081 cgtcacgtcg ccttaccgta tgtatggtta ctgacttcgt cagtttcatc cacaacctca
    10141 aaaacatgtt ttgagctgac ttcgtcagtt tcatccacaa cctcaaaaac atgttttgag
    10201 ctgacttcgt cagtttcatc tgcaacctca aagcagtgct ttgagctgac ttcgtcagtt
    10261 ctatctacaa cctcaaaaac atgttttgag ctgacttcgt cagttctatc tgcaacctca
    10321 aagcagtgct ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgtgttgcg
    10381 cagcctttaa ccagccgcct agtccgctct atggtattca ttaagtcaac atctcttgtt
    10441 taagagcaca aaatcaggaa atcttctcga ttccctgatt ttttctattt acgttttcgt
    10501 gttgagctac gttctgtcaa accatgaggt aagagaactt cacgttcttc caactcttcc
    10561 ttatgcataa tcttggtcaa catacgcata ctaatggcac caaggtcata aagaggttgg
    10621 gcaatcgttg tcaagtttgg acgggtaaag cgtgagattt gtgaatcatc actagtaata
    10681 atttcaaaat cttctggcac agaaacaccc ttatcagcca aaccgttcaa gactcctgct
    10741 gccaactcat cacctgtcac aactgctgca gttgcatttg atgaaatcaa acgctctgct
    10801 aaagcgtaac catcatcata gctatattta gattcaaata ccaaaccctc actataagtg
    10861 attcctgctt ttttcaaggt ttccttgtag ccaactaaac gaaccttacc attgatgtca
    10921 tccactagcg gaccgctaac gaaagcaata cgctcatttt ctttagcaag gtaactcact
    10981 gcatcaattg ttgcttgctt atagtcaata ttgacacttg gcaactggtg ctcaacatcg
    11041 acagttcctg cgagaacaat cggagtacgt gaacgcgaaa attctgagcg aattttatct
    11101 gtcaagtgat aacccatata gataatgcca tctacctgct ttgaaaagag ggtattgaca
    11161 acagaaactt ctttctcgtt atcttcatcg ctattagcta ggacaatatt gtacttgtac
    11221 atttctgcaa tatcatcaat ccccttagcc aaactcgaaa aataaccatt ggtaatattt
    11281 ggaatcacga caccgacagt ggttgtcttt ttacttgcaa gaccacgcgc aactgcattt
    11341 ggacgataat ccaaacgatc aattacctct agcacttttt tacgggtatt ctcttttaca
    11401 tttttattgc cattgaccac acggctgacc gtcgccatgg aaacacctgc ttcacgagcg
    11461 acatcataaa tggttactgt atcatctgca ttcattcctt ttcctgtcct ttctatctca
    11521 cacattcttt tacaagtaga ggtactgatt gaagctctat atctacttac aaaagtgaag
    11581 atgtgaaaat ttcgttttca tatttctact tattccattc tatcactaat tgtaaacact
    11641 ttcaagtgtt ttttgaagat tgattgaaaa aatttcatag aaaacctagg tttagctcct
    11701 tgctaccacc ttagactaaa caaaaaggag gaaactaagc cctcctaaag ttatagtaaa
    11761 atgaaataag aacaggataa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    11821 gaagtagagg tgtactattc tagtttcaat ctactatagg tattgttcca ttcactaccg
    11881 tcaattttag cacatagtct tcatgaaaat attatatcat cataaccaac cagattcttt
    11941 tgcgatatta gctgcctctg ttcgattacc agcatccagt tttgaaagaa tattggtgac
    12001 atagtttcga atagttccgt ttgagaggta aagctgatct gcgatttctt ggttggataa
    12061 gccccgggca attcccttta agacagcaat ctcttgttct gtcaacggat tgggacgggt
    12121 catcaccact tccatcaatt caggtgaata ctccttgcgt ccttcgagga cggtgtgcaa
    12181 ggtttgcatg aggtctgcaa tgcttcgttc ctttaataca taagcatcta ctccaacctt
    12241 gaccgcacgt tcaaaatacc cagcacgctt gaaggtcgtc accacaacca cctttgtttc
    12301 aagcctttct gatcgtatcc actccaagac ttcaagacct gtcttaacag gcatttctac
    12361 gtcaaggatg gcgatatcta cagactcctt ttctaatagt tggattgctt cttgcccatt
    12421 cttggcttga aggacagact ccacatctgg ttgaagcgtg agcaattgac acatggcatc
    12481 tcgcaacata ctttgatctt ctgcgactaa tactttcatc ttagtttctc tccttataag
    12541 gtagtcgaac ttgcacttcc gttggatgtt tctgactgat tacacttact tctcctgaaa
    12601 atggaaaaac acgatctcgg actgtatgga gctcatctcc ttttagaaaa gcaaagccgc
    12661 agccatcatc acttactgtt aaaatgagtt ccttctctgt ccgttctaat tttaagtaag
    12721 ctttagacgc tttggcatgt ttgatgacat tggtcaccaa ctcaagcaaa atcatagaag
    12781 ccattgaatc caattcttga gtaaggctag cagtatctag ttggttatct gtttccacct
    12841 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    12901 acttaagatt ttccacaatg gttcgaactt cacacattga ttctttgcta atttgctgta
    12961 tttctcttaa ttccttttcc acttgtggat aagcctgcat ttgaaatagc tgcaaggcta
    13021 gatctgtctt gacactaagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    13081 cgatacgatt gcgctcattt tctgctagca atagatttat ctgggtattt tgcttgacct
    13141 gagcttcttt caaatcctcg acaaggcgaa ttcgaaccga gcccaaagtc atcaaatcga
    13201 caaaagtaag aattacaagc atatagacta gaaactcaac ttcgattctc tgaaaaatca
    13261 aaagtcgccc cacaacaagg acttgagcaa ggagaaatgt ccatacatgt aaagacttta
    13321 aactacgtac gccaaaatga taaattaaga gattggaaag gaaaaagaaa aaccagatat
    13381 aattcccagc aacaaaggcg gtattcccag ctacatagac cagcatgagc ccccagaaaa
    13441 gccaagatag gcgctggttc ttagttatta aaacacccaa atacgtcact acaaatagaa
    13501 tatcaaccaa taaatgccaa gcaggaagct ccccaatcac tacaggtagg atgggaaaaa
    13561 gcataaaaat caaactggtc caaaacatat agtgtatgct tttcagtctt tcaagcatta
    13621 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    13681 aagtaaataa actgtggctg atagattgat gtccccctcg tttaagaagg tcttgagcaa
    13741 ctccatcaat tgataggtcg ggagacactt accaactgct tgcatccagt ctggaaataa
    13801 agaaatgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    13861 aacagacatc agctgactag ttggtaagag agtcaaggtc aagccaagtg ctacaaaagc
    13921 aatactcccc acaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    13981 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    14041 catacttgtt atctttgata gataatattc taccatattt acagggctat gacgcaatgt
    14101 tttctgccag ttgttcatct tatcggtatg taaaacagct ggaaatgaga ggatagttgt
    14161 cgacatcatg gaaaaggcag tcatggagat gaggtaatca cgcataaaat tcgcgagttc
    14221 acctggtgtg tcctgataga taccagaaaa aaataaatag aaagccgtcg gcatccctac
    14281 cgacaataga taatagatta attgtcgttt ggtcaataaa aattctatct tactaagtgc
    14341 tatccatcgt ttcatcttag ttatctccct tctgcgtctc ttcaaagatt gtattcaaca
    14401 aactacgatt attaacttcg atttcttgca tcctacatcc tgcttgggct aatagttccc
    14461 agaaagcatc tgcttctcga gtgactactt gtaaagaatc ttgctttagg gtccagtttt
    14521 caaccaaatt tgactgctct acgacttcct tgtaagctat aggaaggata aagtgctttt
    14581 ctatttcctc gctacgcata gctagaggcg tcgtatctcg aatcaactct cccttattta
    14641 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    14701 tggtgactcc ttgcgctttt aactcctgga caatttccca aaaacgttga cgagttgagg
    14761 tatccatgga cgcagtaggc tcatctaaaa aaacaatctt tggtcgccca attaaggtca
    14821 agacgaaaga aaagagacgc ttttgaccgc ctgataattt ttctgccaac tgttcttttt
    14881 gttgcttgac aaactgcaat agttgatcaa tttcctgatt gctcaaagga tttggataga
    14941 tacgttgaaa gaaagcaatc aactctttaa cttttaattt ctgaacgatt acattttctt
    15001 gagggaggta agccctagta tagtctaact tagaactcgt cactggtaaa ccttgaatag
    15061 atacttgacc gcttgtgacc agtttatctc caagcaaaca atctaagagt gttgtctttc
    15121 cggcaccatt tggaccaatt aaggcaacac attcaccatc gttgatttca aaggagatat
    15181 tccgcaaaat ttccttgtct tttattttct tactcaattt ctcaacttta accaccgtca
    15241 tgagactctc ctttcaacca ctccattccc ataaggaaaa cgacgaaaat cataaatcca
    15301 aaccccaaag caccacgaat gaattggcga agcaaggctt gatcaaacca atcagtaaac
    15361 atttccacta accataccaa gagtgacagg ccgataaaga aatagatgat ccctttcttc
    15421 attcctcaaa ctcctttttc acatctctga ctaatttcaa accttctcta acaagccaag
    15481 acatgattcc aaagccagca aagaccttcc aaggaaaatg gtagaaatcc tcatccaatc
    15541 ccgaaaacat gagataggtc ataactcctg ctactactaa acttactgcg ataatcattt
    15601 tatttctcat ctcttcttcc cccatttcat actacaatta tagtctttta aaatcagagg
    15661 agacagaagc ttctgtcact agaaaatatg acaaatgtca taaaaaattc tgttcaaaac
    15721 aagcaagata cactatacaa taaaacacaa tcagaaaaat ctaaggcaac ttcctcaaaa
    15781 gagatatcaa acccaattca caccataatg taaactaata cttatttaaa atcaaaaaga
    15841 gtagaaattt ttatcagaca aacacatata tagtgtattg aatctataac agtaggcctt
    15901 aaatactaaa atatttctat aaattaattt aactttcctg atagaactgt tcatatctta
    15961 tttcaattct ctatattata cgttgaacca aacccttcta ttgctttctt aaaaatttat
    16021 aagagttata aaatctgtta aatttcaatg tgtataccta aactacggta tttattgaaa
    16081 agactgggga caaaaagtat acgctgccaa aatgaattac tgaaaatcaa aaaagagaga
    16141 accaaactga ttccctctta atgtatataa tatctagttt taaaaataca cactcacata
    16201 tctctgt
//
LOCUS       DAVHSL010000048        15940 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000048 DAVHSL010000000
VERSION     DAVHSL010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15940
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.050"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            108..1133
                     /gene="trpS"
                     /locus_tag="VVR39_001652"
     CDS             108..1133
                     /gene="trpS"
                     /locus_tag="VVR39_001652"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU6031086.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            1285..2763
                     /gene="guaB"
                     /locus_tag="VVR39_001653"
     CDS             1285..2763
                     /gene="guaB"
                     /locus_tag="VVR39_001653"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU6031087.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(2814..3911)
                     /gene="recF"
                     /locus_tag="VVR39_001654"
     CDS             complement(2814..3911)
                     /gene="recF"
                     /locus_tag="VVR39_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU6031088.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(3914..4282)
                     /gene="yaaA"
                     /locus_tag="VVR39_001655"
     CDS             complement(3914..4282)
                     /gene="yaaA"
                     /locus_tag="VVR39_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU6031089.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            4441..5691
                     /locus_tag="VVR39_001656"
     CDS             4441..5691
                     /locus_tag="VVR39_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6031090.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILDETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            5688..6971
                     /locus_tag="VVR39_001657"
     CDS             5688..6971
                     /locus_tag="VVR39_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6031091.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTNLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            7013..7834
                     /locus_tag="VVR39_001658"
     CDS             7013..7834
                     /locus_tag="VVR39_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6031092.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            7845..8390
                     /gene="pgsA"
                     /locus_tag="VVR39_001659"
     CDS             7845..8390
                     /gene="pgsA"
                     /locus_tag="VVR39_001659"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU6031093.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAIPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            8387..9214
                     /locus_tag="VVR39_001660"
     CDS             8387..9214
                     /locus_tag="VVR39_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6031094.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            9199..10038
                     /locus_tag="VVR39_001661"
     CDS             9199..10038
                     /locus_tag="VVR39_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6031095.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            10031..10825
                     /locus_tag="VVR39_001662"
     CDS             10031..10825
                     /locus_tag="VVR39_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6031096.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRIQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            10884..11702
                     /gene="mreC"
                     /locus_tag="VVR39_001663"
     CDS             10884..11702
                     /gene="mreC"
                     /locus_tag="VVR39_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU6031097.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            11702..12196
                     /gene="mreD"
                     /locus_tag="VVR39_001664"
     CDS             11702..12196
                     /gene="mreD"
                     /locus_tag="VVR39_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU6031098.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            12290..13468
                     /locus_tag="VVR39_001665"
     CDS             12290..13468
                     /locus_tag="VVR39_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6031099.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            13692..14471
                     /gene="rpsB"
                     /locus_tag="VVR39_001666"
     CDS             13692..14471
                     /gene="rpsB"
                     /locus_tag="VVR39_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU6031100.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            14550..15590
                     /locus_tag="VVR39_001667"
     CDS             14550..15590
                     /locus_tag="VVR39_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU6031101.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         5005 a         2522 c         3405 g         5008 t
ORIGIN      
        1 tcctttacac aaatctgtaa aaagcaaggc tgatttattt tgataaatta cggttatttc
       61 attaaaaaaa tgctataatt gaaaggacta tatcgaagga gaacaaaatg actaaaccca
      121 ttattttaac aggagaccgt ccaacaggaa aattgcatat tggacattat gttggaagtc
      181 tcaaaaatcg agtattatta caggaagagg ataagtatga tatgtttgtg ttcttggctg
      241 accaacaagc cttgacagat catgccaaag atcctcaaac cattgtagag tctatcggaa
      301 atgtggcttt ggattatctt gcagttggat tggatccaaa taagtcaact atttttattc
      361 aaagccagat tccagagttg gctgagttgt ctatgtatta tatgaatcta gtttcgttag
      421 cacgtttgga gcgaaatcca acagtcaaga cagagatttc tcagaaagga tttggagaaa
      481 gcattccgac aggattcttg gtctatccaa tcgctcaagc agctgatatc acagctttca
      541 aggctaatta tgttcctgtt gggacagatc agaaaccaat gattgagcaa actcgtgaaa
      601 ttgttcgttc ttttaacaat gcatataact gtgatgtctt ggtagagccg gaaggtattt
      661 atccagaaaa tgagagagca gggcgtttgc ctggtttaga tggaaatgct aaaatgtcta
      721 aatcactaaa taatggtatt tatttagctg atgatgcgga tactttgcgt aaaaaagtaa
      781 tgagtatgta tacagatcca gatcatatcc gcgttgagga tccaggtaag attgagggaa
      841 atatggtttt ccattatcta gatgtttttg gtcgtccaga agatgctcaa gaaattgctg
      901 atatgaaaga acgttatcaa cgaggtggtc ttggtgatgt gaagaccaag cgttatctac
      961 ttgaaatatt agaacgtgaa ctgggtccta ttcgtgagcg ccgtattgaa tttgctaagg
     1021 atatgggaga agtttataat atgattcaaa aaggtagtga aagagcgcgt gaagttgcgg
     1081 gtcaaaccct atctgaggta aaaggggcaa tgggacttca ttactttaac taagtttatt
     1141 ttacaagaaa ctatcatttc tatctcgaag aaaagatagt tttttattta cccctgtaac
     1201 atttgacaaa tttttataga atggtatgat agatacaata taaaaagagt caagctcaaa
     1261 aagaaagaaa agaggaaact tcgaatgtct aattgggaca ctaaattttt gaaaaaaggt
     1321 tttacctttg atgatgtatt gcttattcca gctgaaagtc atgtgttgcc taacgatgca
     1381 gatttaacaa ctaaattggc agataatttg actttaaata tcccaattat taccgctgcc
     1441 atggacacag ttacagagag tcaaatggcc attgctattg ctcgtgcagg tggtctcgga
     1501 gttatccata aaaacatgtc aattgctcaa caagcagacg aggttcgtaa ggtaaaacgt
     1561 tctgaaaatg gagttattat tgatccgttc ttcttgacgc ctgaacatac aattgctgaa
     1621 gcagatgagc ttatgggtcg ttaccgcatc agtggtgttc cagttgttga aacacttgaa
     1681 aatcgtaaat tggttggtat tttgacaaac cgagatcttc gttttatttc agattataat
     1741 caaccaattt caaaccatat gactagtgaa aatcttgtta ctgctcctgt gggtacggat
     1801 cttgcaacgg ctgagagtat tcttcaagag catcgtattg aaaaacttcc gttggtcgat
     1861 gaagaaggca gtctttctgg tttgatcact atcaaagata ttgaaaaagt tattgagttt
     1921 ccaaatgcgg ctaaagatga atttggtcgt cttctagttg caggtgcagt aggtgttact
     1981 tcagatacat ttgaacgtgc agaggctctt tttgaggcag gagcggatgc gattgttatt
     2041 gatactgcac atggtcattc tgcaggtgtc ttgcgtaaaa ttgccgagat tcgtgctcat
     2101 ttcccagatc ggactttgat tgctggaaat attgctactg ctgaaggtgc acgtgccctt
     2161 tatgaagcgg gtgtagacgt tgttaaggtt ggtattggac caggttctat ctgtactact
     2221 cgtgtgattg ctggtgttgg tgttccgcaa gtaacagcta tctacgatgc tgcagctgtt
     2281 gcgcgcgaat atggtaaaac gattattgct gacggtggga tcaagtattc tggagatatt
     2341 gtaaaagcac ttgctgcagg tggaaatgct gttatgcttg gatctatgtt tgctggaact
     2401 gatgaagctc caggcgaaac tgaaatcttc caaggacgta aattcaagac ttaccgtggt
     2461 atgggatcaa ttgctgctat gaagaaaggt tcaagcgacc gttatttcca aggttctgtc
     2521 aatgaagcaa acaagctcgt tccagaagga attgaaggtc gtgttgctta taaaggagcg
     2581 gcagctgata ttgttttcca aatgattggt ggtattcgct ctggtatggg ttactgtggt
     2641 gcagctaacc ttaaagaact acacgataat gctcaattta ttgaaatgtc tggtgctggt
     2701 ttgaaagaaa gccatcctca tgatgtgcaa attactaatg aggcaccaaa ttattctatg
     2761 taaaaaacaa tgaaaagaac tccagtgaaa acaggagttc ttttacaatg ttgtcaattt
     2821 ccatttacag aagctttacc atcctgaata gtgaagatac ttagattttc tggcagattt
     2881 tgaagatggt ctaagcttgt tgttgtgata aaggtttgga ttgattgaga aatcgtttct
     2941 aataatttta actgtctagt gttgtcaagt tcactcatca catcgtcaag cagtaatatc
     3001 ggagattctg tggtaatgct ttccattaat tcgatttctg ctaattttat cgagaggacg
     3061 agactacgat gttgaccttg gcttccgaaa ctagcatcca tcccatttat ataaaaagaa
     3121 atgtcatctc gatgaggacc gacaccagta ttctttttaa ataaatctct ggatctactt
     3181 ttttctaaag caattttgaa agattcggat aagttttgtt tgtcagttat attgacagaa
     3241 gattgatagg atattgacaa ctcttcgatc tgattagaga gttcaaaatg tttcttacgc
     3301 ccaaatgatt ctagtttttt tatgaaatct aagcggtgat tcattacacg acatccataa
     3361 tcaactagct gatcatctaa cacagaaagg aatgtttcat ctattttttg atctgatttt
     3421 aggtaagtgt ttctttgctt taggatgtgg ttataattgg ttaagtcaga taagtagatt
     3481 ggcttaattt gcccaagttc catatcaatg aattttcgtc gaatcgaagg tgctccttta
     3541 attagttgta aatcttcagg agcaaataag acaacattca tgtgtcctac ataatctgaa
     3601 aggcgtgcct gttttaagtg attaactttt gttacacggc ctttttgtgt tagttcgatt
     3661 tctaggggaa tggatccagt ttttttctga acgagacctg aaagatgaag ttgttcctca
     3721 tcaaaatgaa tgagattttt atctgttcga gttcgatgac tacgcgttaa ggctaaaaaa
     3781 tagatagcct ctaacatgtt tgtttttcct tgtgcattac gtcccaaaaa gacattcaat
     3841 ttaggattaa agtctatttt cgtttctttg taattacgaa aagtcttgag agatagatgt
     3901 tgtagccaca tgattatcta ccagggaatc gtggagcttg ttggctttta ggtgatgaag
     3961 caggtttcga tttgtctttt ttaactccct tattcatctt tttgacaagt ttagcgatcc
     4021 gttctttttc aactttatca gcttggtatt catcttgttc ttcagaagta ggttgtgtca
     4081 acaagatgtc aatgttcatg tcagggatgt caactttatc gccaatacga agtttttttc
     4141 cacgacgact ctctaattcc ctattaaagt aaacagaatg ttcagagaga aatgatttaa
     4201 tagctcctcc gctatgtgta attccaagtt ctttgagtag tgcttggagg gtaataaatt
     4261 cttcaaataa tttgtattcc ataattcacc tcaatctttg gtattatacc atattttcct
     4321 aaaaatagtg agagagacag cgagaaatgt aagcgatttt tatttcaaaa gtgttacagg
     4381 gaacaagaaa atttcaggtt ttcgtgatat aatagaagtc tgtatataag gaggtaaatc
     4441 atggagttag tgcatggaat ttcaacacat tttatccaat caaaaaagtt taaaacaaac
     4501 aaaattaccg tgcgttttac cgctccatta tcccttgata cgattgcagg tcacatgttg
     4561 agtgcaagta tgctagagac tgctaatcag atgtacccta cttctcaaga tttgaggaga
     4621 cacttggcca gtctatacgg tacagatatg tcaaccaatt gtttcagaag agggcaaagc
     4681 cacattatag aattgacatt tacctatgtt cgtgatgagt ttttaagtag gaaaaacgtg
     4741 ctaacctctc agattttgga acttgtaaaa gaaactcttt tttcacccgt agtagttgat
     4801 aatgggtttg atccggcctt atttgaaatt gagaaaaaac aattgctagc aagtttagca
     4861 gctgatatgg atgattcttt ttattttgca cataaagaat tggataaatt gttttttcat
     4921 gatgaacgtc ttcaattgga atatagtgat ttacgaaatc gtattttaga tgaaactcca
     4981 caaagttctt attcttgttt ccaagaattt ttagccaatg atcgaataga tttctttttc
     5041 ctaggtgatt ttaatgaggt tgaaattcaa aatgtattag aatcatttgg ctttaaaggt
     5101 cgaaaaggag atgtgaaggt tcagtattgt caaccttatt ctaatatcct tcaggaaggt
     5161 atggttcgga aaaatgtggg acaatccatt ttggaattag gttatcatta ccgttctaaa
     5221 tatggtgatg aacaacattt acccatgatt gtaatgaatg gtttacttgg tggatttgct
     5281 cactctaagc tctttacaaa tgtccgtgaa aatgctggat tagcttatac catttcaagt
     5341 gagcttgatt tatttagtgg attcttgagg atgtatgctg gtatcaatcg agaaaatcgt
     5401 aaccaggctc gtaaaatgat gaataatcaa ctgcttgatt taaaaaaagg ttattttaca
     5461 gagtttgagt taaatcagac caaggaaatg attcgttggt cgttgttact ttctcaagat
     5521 aatcaatctt cattgattga acgtgcttat caaaatgcct tatttggaaa atcttcagca
     5581 gactttaaaa gttggattgc aaagcttgaa caaattgaca aagatgctat ttgtagagta
     5641 gctaataatg tgaaactaca agcgatttac tttatggaag gaatagaatg acaaaggttg
     5701 tttttgaaga aaaatactat ccagctgtaa aagaaatggt ttatcgaact cgtttggcca
     5761 acggattgac agttgctctt ttgcctaaaa aggaatttaa agaggtttac gggagtgtca
     5821 ctgtacagtt tggttcggta gatacgtttg tcacagaagt tgacggagat gtaaaacaat
     5881 atcctggagg aattgctcat tttcttgaac ataaattatt tgagagagaa gattctagtg
     5941 atttgatgtc ggcttttacg aatctaggtg cagatagcaa tgcctttaca agctttacaa
     6001 aaacaaacta tcttttttca gcaacggatt attttttaga aaatttagat ttacttgatg
     6061 aattggtaac atcagcacac tttactgaag cttccattct gacagagcag gatattattc
     6121 agcaagaacg agaaatgtac caagatgatc cagattcgtg tttattcttt tcaactttag
     6181 cgaatttgta tcctggtaca cctttagcaa ctgatatagt tggaagtgag gagtccattt
     6241 cccaaatcaa tctaactaat ttgcaagaaa attttacaaa gttttacaaa cctgtaaaca
     6301 tgtctctgtt tttagttggt aattttgatg tggagcgagt acaggactat tttgaaagca
     6361 aagaactgaa agattcagat tttcaggaag tagcaagaga aaagttgttt ttacagcctg
     6421 taaagctaac agatagtatg agaatggaag tatcttctcc caaactagcg attggagtta
     6481 gaggtaagcg agaagtttct gaagcggatt gctatcgaca tcatatttta ttaaaattat
     6541 tgtttgcaat gatgtttggt tggacttcgg atcgttttca aaaatgttat gaatcaggta
     6601 aaattgatgc gtccttatct ctggaagttg aaataacaag tcgctttcat tttgtcatgt
     6661 tgacaatgga tacgaaagag ccagttgctt tgtctcatca atttaggaag gctattcgta
     6721 attttacaaa ggatttagat attacagagg aacatttaga tattatcaaa agagagatgt
     6781 ttggcgaatt tttcagtagc atgaactctc ttgaatttat tgcaacgcaa tatgatgctt
     6841 ttgaaaatgg tgagacaatt tttgatttgc cgaaaatttt acaggaaatt actttagagg
     6901 atgtccttga tgctggacat catttaatag atgatggtga catagttgat tttacaatat
     6961 tcccatcgta gtaacctatc ataatagaca ctagaaagaa gagatgacaa gtatgagaaa
     7021 aaaaacaatt ggagaggttt tacgattagc tagaatcaat cagggattga gtttagatga
     7081 attgcagaaa aagacagaaa tccagttaga tatgttggaa gcaatggaag cagacgattt
     7141 cgatcaactt ccaagtcctt tttacacgcg ttctttcttg aaaaaatatg catgggctgt
     7201 tgagttagat gaccaaattg ttttggatgc ttatgattct gggagtatga ttacttatga
     7261 ggaagtagat gttgatgaag atgagttgac aggtcgtaga cgttcaagta agaaaaagaa
     7321 gaaaaaaaca tcatttttac ctttatttta ttttatcctt tttgctttat cgattttaat
     7381 ttttgtgact tattatgttt ggaactatat tcaaactcaa ccagaggagc cttctctttc
     7441 taattacagt gtggttcaat caacaagttc aactagctct gttccccact cctcaagtag
     7501 tagttcttct agtatagaat cagctataag tgtatcaggc gaaggaaatc atgtagaaat
     7561 cgcttataag acaagtaagg aaacagttaa attgcaattg gcagtttcag atgttacaag
     7621 ttgggtcagt gtttcagaaa gcgaacttga gggcggtgta accttatcgc caaagaagaa
     7681 aagtgcagaa gcaacagttg caactaaaag tcctgtaaca attacgttag gtgttgtaaa
     7741 aggtgttgat ttgacagtag ataatcagac tgttgattta tcgaaattaa cagctcagac
     7801 tggacaaatc actgtaacct ttactaaaaa ttaaggaaaa acgaatgaaa aaagaacaaa
     7861 ttcccaatct cttaacaata ggtcgaattc tctttatacc tatttttatc tttattttaa
     7921 cgataggaaa ttcgatagag agtcatatag ttgcagctat tatctttgct gttgccagta
     7981 ttaccgacta tttagatgga tatttagctc gtaaatggaa tgtggtcagt aattttggta
     8041 aatttgcaga tcctatggcg gataagttac tagttatgtc ggcttttatt atgttgattg
     8101 agttaggtat ggctccggct tggattgttg cagtgattat ctgtcgtgag ttagctgtga
     8161 caggtttaag gcttttattg gttgaaactg gtggaacaat tttagcagca gcaatacctg
     8221 gaaaaattaa aacttttagt cagatgtttg ctattatttt cttgctatta cattggactt
     8281 tgcttggtca agttctactt tatgtagcct tatttttcac tatctactct ggctatgact
     8341 atttcaaggg tagtgcctat gtatttaaag ggacatttgg ttcgaaatga aatcaataat
     8401 tgatgtaaaa aatctttctt ttcgctataa agaaaatcag aactactacg atgtgaagga
     8461 tattacgttt cacgtgaaac gtggagaatg gctttcgatt gtagggcata atggtagtgg
     8521 taaatcaacg acggttcgat taattgatgg cttactggaa gcagaatccg gagagattgt
     8581 aattgatggc caacgtttga ctgaggaaaa tgtttggaat atacgtcgtc aaatcggtat
     8641 ggtttttcaa aatccagaca atcaatttgt tggagcgact gttgaagatg atgttgcttt
     8701 tggtttggaa aatcagggac tttctcgtca agaaatgaaa aagagagtgg aagaagctct
     8761 ggctttagtt ggcatgttgg actttaaaaa gagagagcca gcgcgtctat caggtggcca
     8821 aaagcaacgt gtggccattg caggtgttgt agccctaaga ccagctattt taatcttaga
     8881 tgaagcaacg agtatgttgg atcctgaggg gcgtagagaa cttattggga cagtaaaagg
     8941 aattcgaaaa gactatgata tgacggtcat ttctattacc catgatttgg aagaagtcgc
     9001 catgagtgat cgcgtattgg tcatgaaaaa aggggaaatt gaatcaacta gtagtccaag
     9061 ggagcttttc tctcgaaatg atttagatca aattggatta gacgatcctt ttgctaatca
     9121 attaaaaaaa tctttgagcc agaatggcta tgatttacct gaaaattatt tgacagaaag
     9181 tgagctagag gataagctat gggaattgct ctagaaaatg tgaattttac atatcaagaa
     9241 ggtactccct tagcttcagc agctttgtcg gatgtttctt tgacgattga agatggctct
     9301 tatacagctt taattgggca cacaggtagt ggtaaatcaa ctattttaca actcttaaat
     9361 ggtttattgg tgccaagtca agggagtgtg agggtttttg ataccttaat cacctcgact
     9421 tctaaaaata aagatattcg tcaaattaga aaacaggttg gcttggtatt tcagtttgct
     9481 gaaaatcaga tttttgaaga aacggttttg aaggacgttg cttttggacc gcaaaatttt
     9541 ggagtttctg aagaagatgc tgtgaagact gcgcgtgaga aactggctct ggttggaatt
     9601 gatgaatcac tttttgatcg tagtccgttt gagctgtcag ggggacaaat gagacgtgtt
     9661 gccattgcag gcatacttgc catggagcca gctatattag tcttagatga gccaacagct
     9721 ggtctagatc ctctagggag aaaagagttg atgaccctgt tcaaaaaact ccaccagtca
     9781 gggatgacca tcgtcttggt aacgcatttg atggatgatg ttgctgaata tgcgaatcaa
     9841 gtctatgtaa tggaaaaggg acgtttagta aaggggggca aaccaagtga tgtctttcaa
     9901 gacgttgttt ttatggaaga agttcagttg ggagtaccta aaattacggc cttttgtaaa
     9961 cgattggctg atagaggcgt gtcatttaaa cgattaccga ttaagataga ggagttcaag
    10021 gagtcgctaa atggatagta tgattttggg gcgttatatc ccaggggatt cgattgttca
    10081 ccgattggat ccacgtagca aattgcttgc tatgatgcta ctgattttga ttgtgttttg
    10141 ggctaataac cccttgacga atctgattct ttttatagcg acagggatat ttattgcctt
    10201 gtcaggagta tctctttcat tttttattca gggcttgaag tctatgtttt tcttgattgc
    10261 cttcacaact atttttcaac tatttttcat ttctaatggg aatgttttat ttgagttttc
    10321 gtttgtgaga atcacggatt atgctttgca acaagctggg attatttttt gtcgctttgt
    10381 attgattatt ttcttttcaa ctttgttaac cttaacaacc atgcctttaa gtttggcatc
    10441 agctgtcgaa gctttattag cacctttaaa gcgtgtgaaa gttccagttc atgaaattgg
    10501 attgatgctg tctatgagtt tgcgttttgt cccaaccttg atggatgata cgactcggat
    10561 tatgaatgca cagaaagctc gtggagtgga ttttggagaa ggaagcatcg ttcaaaaagt
    10621 aaaggcgatg attcccattt tgattcctct ttttgcgaca agtttaaaac gtgcagattc
    10681 cttggctatc gctatggaag cgcgtggcta tcagggtgga aaaggcagaa ttcaataccg
    10741 acaattgaaa tggactctaa aggatacgct gaccattctt gttattctcg tacttggttg
    10801 ttgtttattt ttcttaaaat cttagtagct ttcaggaatt gataaaaagt tactgtaaca
    10861 gtttttgata gaaaggtagg gatatgaacc gttttaaaaa atcaaaatat gtcattattg
    10921 tttttgtcac tgttctgctt gtgtcagctc tcttagcgac gacttattca agtacaattg
    10981 tgacaaaatt aggagatgga atctcattgg ttgatagagt tgtacaaaaa ccttttcagt
    11041 ggtttgattc tgtcaaatca gatttggctc atttgacacg aacatataat gaaaatgaaa
    11101 gtttgaagaa acagctttac caattagaag ttaaatcaaa tgaggtggaa agtttaaaga
    11161 cagaaaatga acaactgcgc caattgcttg atatgaagtc taaattgcaa gccacaaaga
    11221 ctttagcagc agatgttatt atgcgttctc cggtatcttg gaagcaggag ttgaccttag
    11281 atgcaggtag atcaaaaggt gcttctgaga acatgttagc tattgcaaat ggtggcttga
    11341 ttgggagtgt ttcaaaagta gaggagaact ctactatagt caaccttctg acaaatacgg
    11401 aaaatgctga taagatttct gttaaaattc aacatggctc tactacaatt tatggaatta
    11461 ttattggcta tgacaaggaa aatgacgttc ttaaaattag ccaattaaat agtaatagcg
    11521 atattagtgc gggagataag gtgactactg gtggattagg aaactttaac gttgctgata
    11581 ttcctgttgg tgaagtggtt gccacaacgc atagtacaga ctatttgaca cgagaagtaa
    11641 ctgttaaatt gagtgcagat actcataatg tagatgtgat agaattagtg gggaattcat
    11701 aatgagacag ttgaagcgag ttggagtatt tttattgctt cctttctttg ttctaattga
    11761 cgcccatatt agccagcttc tgggctcatt tttcccccat gtacatttgg ctagtcattt
    11821 tctttttcta tttctcttat ttgagacgat agaagtatca gagtatctct acctagtcta
    11881 ttgttttgtt ataggcttgg tttatgatgt ttactttttc catctaatag ggattacaac
    11941 tctcttattt atcttattgg gagccttcct tcataaattg aatagtgtta ttttgttgaa
    12001 tcgttggaca agaatgctag ctatgattgt gctgacattc ctgtttgaaa tgggtagtta
    12061 tcttttggct tttatggtag ggttgacagt agatagcatg tcgattttta tagtctatag
    12121 cttggtaccg acgatgattt taaatttttt atggattact gtttttcaat ttatttttga
    12181 aaaatattat ctataagaac gacatataaa tgtaacaaag gcgtaatatt tattaggcct
    12241 ttttttggta tactagtatt gtctttaaaa gaaggagtat ctacgtaata tgaagaaaaa
    12301 aatcttagcg tcacttttat taagtacagt aatggtttct caagtagctg ttttaacaac
    12361 tgcgcatgca gaaacgactg atgacaaaat tgctgctcaa gataataaaa ttagtaactt
    12421 aacagcacaa caacaagaag cccaaaaaca agttgaccaa attcaggagc aagtatcagc
    12481 tattcaagct gagcagtcta acttgcaagc tgaaaatgat agattacaag cagaatctaa
    12541 gaaactcgag ggtgagatta cagaactttc taaaaacatt gtttctcgta accaatcgtt
    12601 ggaaaaacaa gctcgtagtg ctcaaacaaa tggagccgta actagctata tcaataccat
    12661 tgtaaactca aaatcaatta cagaagctat ttcacgtgtt gctgcaatga gtgaaatcgt
    12721 atctgcaaac aacaaaatgt tagaacaaca aaaggcagat aaaaaagcta tttctgaaaa
    12781 acaagtagca aataatgatg ctatcaatac tgtaattgct aatcaacaaa aattggctga
    12841 tgatgctcaa gcgttgacta cgaaacaggc agaactaaaa gctgctgaat taagtcttgc
    12901 tgctgagaaa gcgacagctg aaggggaaaa agcaagtcta ttagagcaaa aagcagcagc
    12961 tgaggcagag gctcgtgcag ctgcggtagc agaagcagct tataaagaaa aacgagctag
    13021 ccaacaacaa tcagtacttg cttcagcaaa cactaactta acagctcaag tgcaagcagt
    13081 atctgaatct gcagcagcac ctgtccgtgc aaaagttcgt ccaacataca gtacaaacgc
    13141 ttcaagttat ccaattggag aatgtacatg gggagtaaaa acattggcac cttgggctgg
    13201 agactactgg ggtaatggag cacagtgggc tacaagtgca gcagcagcag gtttccgtac
    13261 aggttcaaca cctcaagttg gagcaattgc atgttggaat gatggtggat atggtcacgt
    13321 agcggttgtt acagctgttg aatcaacaac acgtatccaa gtatcagaat caaattatgc
    13381 aggtaatcgt acaattggaa atcaccgtgg atggttcaat ccaacaacaa cttctgaagg
    13441 ttttgttaca tatatttatg cagattaatt tacagaggga ctcgaataga gccctctttt
    13501 caggttttac cgtgacaatc cctattaaaa attatatcaa aatagcttga aaatattgga
    13561 aaagtatggt aaaatgaaaa ttgtcgtgtg aacgataata ctcattcttg atgaattgtg
    13621 aagcagttgc ccttgggtcg ttttgcgagt tgaagtcaag aagaggaaaa aaacaaaaag
    13681 gagaaatact catggcagta atttcaatga aacaacttct tgaggctggt gtacactttg
    13741 gtcaccaaac tcgtcgctgg aatcctaaga tggctaagta catctttact gaacgtaacg
    13801 gaatccacgt tatcgacttg caacaaactg taaaatacgc tgaccaagca tacgacttca
    13861 tgcgtgatgc agcagctaac gatgcagttg tattgttcgt tggtactaag aaacaagcag
    13921 ctgatgcagt tgctgaagaa gcagtacgtt caggtcaata cttcatcaac caccgttggt
    13981 tgggtggaac tcttacaaac tggggaacaa tccaaaaacg tatcgctcgt ttgaaagaaa
    14041 ttaaacgtat ggaagaagat ggaactttcg aagttcttcc taagaaagaa gttgcacttc
    14101 ttaacaaaca acgtgcgcgt cttgaaaaat tcttgggtgg tatcgaagat atgcctcgta
    14161 tcccagatgt gatgtacgta gttgacccac ataaagagca aatcgctgtt aaagaagcta
    14221 aaaaattggg aatcccagtt gtagcgatgg ttgacaccaa tactgatcca gatgatatcg
    14281 atgtaatcat cccagctaac gatgacgcta tccgtgctgt taaattgatc acagctaaat
    14341 tggctgacgc tattatcgaa ggacgtcaag gtgaggatgc agtagcagtt gaagcagaat
    14401 ttgcagcttc agaaactcaa gcagattcaa ttgaagaaat cgttgaagtt gtagaaggcg
    14461 acaacgctta atttatacaa atagtaatta cctaggaggg cggggcttag cccggctctc
    14521 ctattttcaa aaaatgtagg agaattaaaa tggcagaaat tacagctaaa cttgtaaaag
    14581 agttgcgtga aaaatctggt gccggtgtta tggacgctaa aaaagcgctt gtagaaacag
    14641 acggtgacat cgaaaaagcg attgaattgc ttcgtgaaaa aggtatggct aaggcagcta
    14701 agaaagctga ccgtgttgct gcagaaggtt tgactggtgt ttatgttaac ggtaatgttg
    14761 cagcagttat tgaagtaaac gctgaaactg acttcgttgc aaaaaacgct caattcgttg
    14821 aattggtaaa tactacagcg aaagtcattg ctgaaggaaa acctgctaac aacgaagaag
    14881 ctcttgcttt gataatgcct tcaggtgaaa ctcttgaagc tgcatacgta tctgcaacag
    14941 caactatcgg agagaaaatc tcattccgtc gctttgcatt gattgaaaaa acagacgcac
    15001 aacactttgg agcataccaa cataacggtg gacgtatcgg tgttatttca gttgttgaag
    15061 atggagacga agcacttgct aaacaattgt caatgcacat cgcagcgatg aaaccaacag
    15121 ttctttctta caaagaattg gatgagcaat tcgttaaaga tgagttggca caattgaatc
    15181 acgttatcga ccaagacaac gaaagccgtg caatggttaa taaaccagct cttccacact
    15241 tgaagtatgg atcaaaagct caattaactg atgatgttat tgctcaagct gaagctgaca
    15301 tcaaagctga attggctgca gaaggcaaac cagaaaaaat ctgggacaaa attattccag
    15361 gtaaaatgga tcgcttcatg cttgataaca ctaaagttga ccaagcttac acacttcttg
    15421 cacaagttta tatcatggat gacagcaaga cagttgaagc ataccttgaa tcagttaacg
    15481 cttcggtagt tgagtttgct cgctttgaag ttggtgaagg tatcgagaaa gctgcaaacg
    15541 acttcgaagc tgaagttgca gctacaatgg cagcagcctt gaataactaa taatagaaag
    15601 gaagcaaatt gcttcctttt ttgtataggg cttagatttt tcctgaaatt gttttttccc
    15661 cagtctcact cgattagaat aattaaaaca aaaagcccta taataagggc taagtgcatt
    15721 taggagacta tacttcaaat tcatagtaag cgcgtcataa caaggtatct atcctaattc
    15781 cccaacttcc agtatactag ataaaaaata attatcggag gaaaggtatt gtactatgat
    15841 aattcaacta agtgatttag gtcaagttca ccttgtttgt ggcaagacag atatgaggca
    15901 gggaatagac tcattagcct atgtagttaa aacccacttt
//
LOCUS       DAVHSL010000049        15745 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000049 DAVHSL010000000
VERSION     DAVHSL010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.051"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            12..152
                     /locus_tag="VVR39_001668"
     CDS             12..152
                     /locus_tag="VVR39_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutT"
                     /protein_id="HEU6031102.1"
                     /translation="MNDRYLVMTRLLFYDMLPLMEMMVAPDKSEFFYPRRTEDDWEKK
                     IF"
     gene            complement(149..664)
                     /locus_tag="VVR39_001669"
     CDS             complement(149..664)
                     /locus_tag="VVR39_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU6031103.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(676..1203)
                     /locus_tag="VVR39_001670"
     CDS             complement(676..1203)
                     /locus_tag="VVR39_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6031104.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(1485..2048)
                     /locus_tag="VVR39_001671"
     CDS             complement(1485..2048)
                     /locus_tag="VVR39_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6031105.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(2032..2583)
                     /gene="coaC"
                     /locus_tag="VVR39_001672"
     CDS             complement(2032..2583)
                     /gene="coaC"
                     /locus_tag="VVR39_001672"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU6031106.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(2595..3284)
                     /gene="coaB"
                     /locus_tag="VVR39_001673"
     CDS             complement(2595..3284)
                     /gene="coaB"
                     /locus_tag="VVR39_001673"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU6031107.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            3514..5184
                     /locus_tag="VVR39_001674"
     CDS             3514..5184
                     /locus_tag="VVR39_001674"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU6031108.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            5512..6687
                     /gene="mutY"
                     /locus_tag="VVR39_001675"
     CDS             5512..6687
                     /gene="mutY"
                     /locus_tag="VVR39_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU6031109.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            6742..7446
                     /locus_tag="VVR39_001676"
     CDS             6742..7446
                     /locus_tag="VVR39_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6031110.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            7439..8788
                     /gene="vicK"
                     /locus_tag="VVR39_001677"
     CDS             7439..8788
                     /gene="vicK"
                     /locus_tag="VVR39_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU6031111.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            8790..9599
                     /locus_tag="VVR39_001678"
     CDS             8790..9599
                     /locus_tag="VVR39_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6031112.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            9690..9932
                     /locus_tag="VVR39_001679"
     CDS             9690..9932
                     /locus_tag="VVR39_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU6031113.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            9934..10188
                     /locus_tag="VVR39_001680"
     CDS             9934..10188
                     /locus_tag="VVR39_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU6031114.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            10235..11008
                     /locus_tag="VVR39_001681"
     CDS             10235..11008
                     /locus_tag="VVR39_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU6031115.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(11268..12254)
                     /locus_tag="VVR39_001682"
     CDS             complement(11268..12254)
                     /locus_tag="VVR39_001682"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU6031116.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIIRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            12448..14916
                     /gene="gyrA"
                     /locus_tag="VVR39_001683"
     CDS             12448..14916
                     /gene="gyrA"
                     /locus_tag="VVR39_001683"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU6031117.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            14916..15659
                     /gene="srtA"
                     /locus_tag="VVR39_001684"
     CDS             14916..15659
                     /gene="srtA"
                     /locus_tag="VVR39_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU6031118.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4836 a         2735 c         3492 g         4682 t
ORIGIN      
        1 ggaggagctc catgaatgat agataccttg ttatgacgcg cttactcttc tatgatatgc
       61 taccattgat ggaaatgatg gtagctcccg acaagtcaga gtttttctat cctcgccgta
      121 cagaagacga ttgggaaaag aaaatcttct agtcttttac taaataacct agctgatcca
      181 aggcctcctc gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga
      241 tgccatctgt caattcagat agaggtctaa agtcagaatg ctcgacttgt tctagaaaat
      301 gttgcacatc tctgcgacaa gacagtttaa gcaaggtttc aatttctcca taaacgggat
      361 ggtcaatcaa ggtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac
      421 cgatttcttc aacttcatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa
      481 tttgcttata gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa
      541 ttgcaatgtc ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc
      601 cattaagggc tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg
      661 tcatagcttt tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt
      721 atagtctacc atactatgga taattgtgcc aaatccaact agtacaaata gaacatagaa
      781 catgttttct acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc
      841 aagggcatga acaacagcca aaacaaaatt gaaaacccag gaagattttg gtttatctag
      901 ggtatcgggg aatttttgta ggtaaagagc tcctaaagca ccaaaagata tatgggaaaa
      961 agcccgaaaa acgataacca tgggatagcc agccatcaaa aatccaaaac tagaggctag
     1021 gatgacaaaa actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct
     1081 ccccaaagta taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa
     1141 aatcgcaata gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt
     1201 cacaagaatc tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa
     1261 agcaagaatt tacttgggtt tatagatcat tttttagtta aaagttatag tagattgaaa
     1321 ctagaatagt ccacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
     1381 gatttgtcct gttcttattt cgttttacta tagtaaagat ttcattaaaa agaaactgta
     1441 tagagcaaaa tctccacctt caggtttgaa agcggagatt gtttttattt tttcaaggtt
     1501 tgtagtcgtg gaacaatggc tagggttaga attgcagaaa tgaccaattc agcaattgaa
     1561 tttgttgaga taacggttgc cagaagaagt tggatatttc cattataaac atttccaaat
     1621 aggaagaaga ttcctccaag gacaaagata gtatttgtca aggaaccaag ggctccagct
     1681 aaaatcagac cagtcttgtt tttcatcagt ttatagacta agtaaggagt taaaccaatc
     1741 aaaatacgtg ggacgatggc aatgatagct gagtagatgt ttccgtttgg tacgaaggga
     1801 gagaagaggt agcttgtcgg tagaatcgta atcgtgttaa ccgtcaagct aagtaatccc
     1861 atcaaaaatc caagtgtaac cccaactcgt ggaccataaa taatgctggc aataatgaca
     1921 ggaatatgaa caatggtcgg tttgattgga aatggaaaaa ggttaaagat aagtgagctc
     1981 agaaagtgta tcacgagcat ggtagcaaaa aagatagcaa tgggtgcaat attagagcgt
     2041 tttttcatcg atagtttcct ttattctttc taaaataatt gtgaggtcag ctaaagctcc
     2101 tcgtccgtgg tctccacaag ctagtaggga ttccttagga gcaatcagct gatagccgta
     2161 ggtttctaat gttttcagat tattctgagt tactggatgg tcatacattt ttgtattcat
     2221 agcaggagct attagtttgg gaatatgact tggtagggct agagctgtac tggttaccat
     2281 gttgtccgca aatccgtgag ctagttttgc aatagtgtta gcagttgcag gtaccacgat
     2341 aaataaatct gctttttttc caagttcgat atgattgacc tgatcaggat agggttcctt
     2401 catgacatcc aagtggacag gattctgtga gagtacctgt agtgtcaaag gttggataaa
     2461 ctctgtagca gcctgagtca ttaagacagt gacttgatgg ccttgttttt ttagagaact
     2521 gactaaatct gccgacttat aagaggcgat tgaacccgtt acagccaaga gaatgtttgc
     2581 catagttttc ctttctaaga atgataggct tgaatttttt caaggaggag ttctgcaatt
     2641 tcttctttag tctggactgt ttgaagctga tttttctcaa caaatatagc tcggtgctga
     2701 tctgctgaaa tttgagtcag gtcattcgcg atgattaaat ctgcttgatt cttgataaga
     2761 ctttttcgtg caatgtcaac cagatgatct tcggtaacat caaccagcag tttgaaacca
     2821 atcagatgaa tagtgggatt ccattccttg actagggata tgattttggg tgtcttttta
     2881 aggaacaaaa cctgaacctc atcagttgaa gaaatcttgg cctgatgatt ctgcttgctt
     2941 aaaaattctt ttagattgga gctagcctga acttcctcaa gccctgtcat ataaacagga
     3001 gtgtagtcag aaacagccat tgagtggatc aagacctgat aatcctgaac acgttcttgc
     3061 atttctatta gaaggtcctt ggtattggta atttctcgaa tacttaggtt aggatgaggc
     3121 tctggcttca gagctcgttt tgtcgtaatt aaacaaactt catgccctgc agaaagcaaa
     3181 gtctctgtga taattttccc caagtgacct gtagaatggt tagtgataga gcggacgcta
     3241 tcgatagctt cactggtacc gcccgatgta actaaaattt tcatagcact attgtacaca
     3301 aaaataagcg gtaagtaaaa tgaaagtgat aaatttttgg taaaaacgaa gatttactat
     3361 agtttcaaac tataaagcca tataaaattt aagaaaggac tctaaaagtc ttaaaaacag
     3421 agatatttac gaacgtttag agagttttaa gatgttaaaa atcttgtttt gtgatataat
     3481 gaattatcat ataagaggtt agaggaattt tgaatgaaaa cagatattga aatcgcacag
     3541 agtattgagt tgaagccaat tgttgatgtt gtagagaaac ttggtatttc ttacgacgat
     3601 ttggagttgt acggaaagta caaggctaaa ctcagctttg ataaaattcg ggcagttgag
     3661 agcaatccag tcggtaaatt gatcttggtt actgccatca acccaacacc tgcaggtgaa
     3721 ggaaagtcga cgcttaccat tggtcttgcg gatgccttga acaagattgg caagaaaacc
     3781 atgattgcta tccgcgaacc gtctcttggt ccagtcatgg ggatcaaggg tggtgctgct
     3841 ggtggtgggt atgcacaagt tctgccaatg gaagacatca acctccactt tactggagat
     3901 atgcatgcta ttacaactgc caacaatgcc ctttctgcct tgattgacaa ccacttgcac
     3961 caagggaatg agctgggaat tgatcaacgt cgtatcctct ggaaacgcgt tgtggacttg
     4021 aacgaccgtg cgctccgcca tgtgactgtt ggtcttggtg gtcctctaaa cggtattcca
     4081 cgtgaggacg gttttgatat tacagttgct tcagaaatca tggcaattct ttgcttggca
     4141 acggacatcg aggacttgaa acgtcgtttg gcgaatatcg ttattggtta tcgctatgac
     4201 cgtacgcctg tttctgtagg tgatttgcag gttgagggtg ccttggcttt gattttgaag
     4261 gatgctatta agccaaactt ggttcagaca atttacggta cacctgcctt tgtacacggt
     4321 ggtccatttg ccaatatcgc tcatggctgt aactctgttt tggcgacgac aacagccctt
     4381 cacttggctg attacactgt tactgaagct ggttttggtg cggatcttgg tgctgagaaa
     4441 ttccttgata tcaagacacc aaacttgcca acatctccag atgcagttgt tattgtcgca
     4501 acccttcgtg cccttaagat gaatggtggt gtggctaaag acgctctgac tgaagaaaat
     4561 gtagaggcag ttcgtgcagg ttttgctaac ttgaaacgcc acgttgaaaa tatccgtaag
     4621 ttcggtattc cagcagttgt agctattaac gaatttgtat ctgatacaga agctgaaatt
     4681 gcagtcttaa aagaactctg tgcctcaatc gatgtaccag ttgaattggc tagtgtctgg
     4741 gctgatggag cagaaggtgg agtagcactt gccgaaacag ttgttaagac aattgctgaa
     4801 aatccagcta actataaacg tttgtacgat aatgaccttt ctgtccaaga aaagattgaa
     4861 aaaattgtca ctgaaatcta tcgtggtagc aaagtgaact ttgagaagaa agctcaaaca
     4921 caaattgctc aaatcgttca aaacggttgg gacaaattgc caatttgtat ggctaaaact
     4981 caatacagtt tctcagacaa tccaaatgcg cttggagcac cagaaaactt tgaaattacc
     5041 attcgtgaat tggtaccaaa attaggtgca ggcttcatcg ttgccttaac tggtgatgtt
     5101 atgaccatgc caggtcttcc aaaacgtcca gcagctctca acatggatgt tgaaagcgat
     5161 ggaactgtgc taggcttgtt ctagtggatt gaaattgact ttaagtgagt ttggaaataa
     5221 tatccaagct cattttttct cagactgcaa gcagttcatc aataagattt atactcttcg
     5281 aaaatctttt caaactacgt cagcttcacc ttgccgtagg tatatgatac tgactctgtc
     5341 agttctatcc acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg
     5401 ctctttgatt ttcattgagt ataagtagat agaaaagtta tatactatct attgaaaata
     5461 ttataaatca gatacaaaga caggtgaaac cttctgtgtt atactagaga tatgttagat
     5521 ttgaaagaat acggtatcgt catgtggccg gaggagaaag tcatttcttt ccgtgagaaa
     5581 cttctcgctt ggtatgatga aaacaaaaga gatttgcctt ggaggagaag taaaaatcct
     5641 tatcacatct gggtatctga aatcatgctt cagcagacca gggtggatac agttatccct
     5701 tactacgaaa gatttttgga ctggtttcca actgtcgaaa gtctggcaac tgcgcctgag
     5761 gagagtttac tgaaagcttg ggagggcttg ggctattatt ctcgagttcg caatatgcag
     5821 gctgcagccc agcagattat gactgacttt ggtggccaat ttccaaatac ctatgaagga
     5881 atttccagct tgaaagggat tggaccttac acagcaggag ccatttccag tattgctttt
     5941 aacttgcctg agccagctgt agatggtaat gtcatgcggg tcttggcgcg tctgtttgaa
     6001 gtcaaccacg atattgggat tccaagtaat cgaaaaattt ttcaggcaat gatggagatc
     6061 ttgattaatc cagatcgtcc aggtgatttt aatcaagcct tgatggactt agggtctgat
     6121 attgagtctc ctgtaaatcc cagacctgaa gaaagcccag tcaaggactt tagtgcggca
     6181 tatcagaatg gaaccatgga ccgttatcca attaaatctc ctaagaaaaa gccggttcct
     6241 atttatctta aagccttagt tgtgaaaaat tctcaaggac aatttttact tgaaaaaaat
     6301 gaaagcgaaa agctcttggc aggtttttgg catttcccct ttatagaagt tgataacttt
     6361 tcgcaagaag agcagtttga cctctttcat caggttgcgg aagaaagtgt gaactttggc
     6421 cccagtccag aagagagttt ccagcaggac tatgacctag atgttgattg gcttgatgtt
     6481 tgttttgata cagtccagca tgtttttagt catcgaaaat ggcatgtaca gattgtagca
     6541 ggtcaggtga gtgacttcca tgatttttca gatagggaag ttcgttggct ttcaccagaa
     6601 gaattcaaga attacccact tgccaaaccc caacaaaaaa tctggcaggc ttatgcacaa
     6661 gccaacttag acagtagcca agactagcta ttgtgtcttc tgactatttt ttggtataat
     6721 agtagagaaa aaggtgaaca tatgaaaaaa atactaattg tagatgatga gaaaccaatc
     6781 tcggatatta tcaagtttaa tatgaccaag gaaggttacg aagttgtaac tgcttttaat
     6841 ggtcgtgaag cgctagagca atttgaagca gagcaaccag atattattat tctggatttg
     6901 atgcttccag aaattgatgg tttagaagtt gctaagacca ttcgtaagac aagcagtgtg
     6961 cccattctta tgctttcagc caaagatagt gaatttgata aggttatcgg tttggaactt
     7021 ggggcagatg actatgtaac gaaacccttc tccaatcgtg agttgcaggc gcgtgttaaa
     7081 gctcttctgc gtcgttctca acctatgcca gtagatggtc aggaagcaga tagtaaacct
     7141 caacctatcc aaattgggga tttagaaatt gttccagacg cctacgtagc taaaaaatat
     7201 ggcgaagaac tagacttaac ccatcgtgaa tttgagcttt tgtatcattt agcatcgcat
     7261 acaggtcaag tcatcacgcg cgaacacttg cttgagactg tctggggtta tgactatttt
     7321 ggtgatgtcc gcacagttga tgtgactgta cgacgtctgc gtgagaagat tgaagatacg
     7381 cccagccgac cagagtatat cttgacgcgc cgtggtgtag ggtattacat gagaaataat
     7441 gcttgattta ctgaaacaaa ccatttttac cagagatttt atctttatcc tgattttgtt
     7501 aggtttcatc cttgttgtga ccctcttatt actggaaaat agacgtgata atattcagtt
     7561 gaagcaaatc aatcaaaagg ttaaagattt gattgcagga gattattcca aggttcttga
     7621 tatgcaaggt gggtctgaaa tcaccaatat taccaataat ttgaatgact tgtcggaggt
     7681 tattcgtctc actcaggaaa atctagaaca agagagtaag aggctaaata gtattctgtt
     7741 ttatatgaca gatggggttc ttgcgaccaa ccgtcggggt cagattatca tgattaacga
     7801 tacagccaag aagcaactgg ggttggttaa ggaagatgtt ctgaatagaa gcattttgga
     7861 attgctcaag atagaagaaa actatgaatt gcgtgatttg attacccaaa gtccagaatt
     7921 gttgctagat tcccaagata tcaatggcga atatttgaac cttcgagttc gctttgcctt
     7981 gatacgtcga gagtctggct ttatttcagg tttggtggct gttttgcatg atacgacgga
     8041 gcaggagaag gaagaacgcg aacgaagact ctttgtttcc aatgttagcc atgagttacg
     8101 gactcctctg actagcgtaa aatcctatct tgaagccttg gatgaggggg ctttgtgtga
     8161 aactgtagca ccagacttta tcaaggtttc tcttgatgag accaaccgta tgatgcgcat
     8221 ggtgacggat ctcctccatc tttcacgtat tgataatgct accagtcacc tagatgtgga
     8281 actgattaac ttcactgctt ttattacctt tatcctcaat cgttttgaca agatgaaagg
     8341 acaggaaaag gagaaaaaat atgagttggt gagagattat cccatcaatt ctatctggat
     8401 ggaaattgat acagataaga tgacgcaggt tgtcgacaat attttaaata atgctattaa
     8461 gtattcgcca gatgggggta aaatcactgt cagaatgaag acaactgaag accagatgat
     8521 tttatccatt tctgaccacg gtttggggat tcctaagcag gatttaccac gtatctttga
     8581 ccgtttctat cgtgtggatc gtgctagaag tcgtgcacaa ggtggtacag gtctaggact
     8641 gtctatcgct aaagaaatta tcaaacaaca taagggcttt atttgggcca agagtgaata
     8701 cggcaagggt tcaaccttta ccattgtgct cccttatgat aaggatgcag tgaaagaaga
     8761 agtatgggag gatgaagtag aagactagaa tgagtgaaat aggctttaaa tacagtattt
     8821 tagcgtcggg ttccagtgga aattcttttt atctggaaac ctcaaaaaag aagcttttag
     8881 tagatgcagg cttgtctggc aagaaaatta ccagtctgct agctgaaatt aaccgtaagc
     8941 cagaagacct ggatgccatc ttgattaccc atgagcattc agatcatatc catggagtag
     9001 gcgttttggc tcgcaagtat ggtatggatc tttatgccaa tgaaaagacc tggcaagcta
     9061 tggaaaatag taaatatctt ggcaaggtgg attcttcgca aaagcatatt tttgaaatgg
     9121 gtaaaaccaa aacctttgga gatatcgaca tcgagagttt tggtgtaagc catgatgcag
     9181 tcgcaccgca gttctatcgc tttatgaagg atgataagag ttttgtcctc ttgacagata
     9241 caggttatgt cagtgaccgt atggcgggca ttgtcgaaaa tgcggatggt tatcttatcg
     9301 aggccaacca tgatgtagag attttgcgat caggttctta cgcttggcgc ctcaaacaac
     9361 gaatcctatc tgaccttggt cacctttcta acgaggacgg tgctgaagct atgattcgga
     9421 cgctaggaaa tcgtactaag aagatttacc ttgggcattt atctaaggaa aacaatatca
     9481 aggaactggc tcatatgacc atggtcaatc agctggctca agctgatctg ggagtcggag
     9541 tagactttaa ggtttatgat acctcaccag ataccgcaac accattgaca gagatataga
     9601 aagaacgctg agaaggtgtt ctttttatat tgactggaca cctaaaaagt aatacaatgg
     9661 tgttaccatt aaaaaaggga gcacaaaaga tgactactat tacattaaaa gtttctgaag
     9721 ctgataaaac atttatgaaa gcaatggcta agtttgaagg agtttccctt tcggaactta
     9781 ttcgcaccaa aactcttgaa gccctagaag atgaatacga tgctcgtgtg gcagatttag
     9841 cctatcaaga gtatttagaa gacttggaaa aaggagttga acccattact tgggaagaaa
     9901 tgatgcatga tttaggcttg aaggatgaat aatttgtata aattagttcc aacaagacgt
     9961 tttatcaagc aattgaaaaa attggaccgt tatacgcaga agctaattac aaactattta
    10021 caaaccaatg ttttggaaga tccaagacga cacggaaagg ctttggttgg taatcgcgtt
    10081 ggtcaatggc gctatagaat tggtaattat cgagttatcg tacaaattgt agatgatgaa
    10141 ttagttgttg ctactctaga agttggtcat cggagagata tttattgaat taaagctgag
    10201 taataacaat atagaaagta aggagagtaa aaatttgaag aaaaaatggt tttttgcaga
    10261 ttattatgat acaacaatta ttttacttgc tttaatctct gttattctgg tattacttgg
    10321 atttgctgag atgattgatt tggacaatcc gccttatagt attattgatt tagtaatctg
    10381 gggtgttttt gtaattgatt atagttggcg cttttttacg actaaaagaa aatggcgctt
    10441 tattcttgaa aatatttttg atttattggc tattctccct ttaaatgcta tttttacagt
    10501 gtttcgatta gggcgtatct ttcgtttagt taaactaaca aaattactga aactgactcg
    10561 tttacttaga ataattggac ttacaggtaa attagaaaga aaaattagta gattcttacg
    10621 gacaaatggc ttgatttata tcttgtatgt taatatcttt atcgtgctag taggaagttc
    10681 aattttatct gtagttgaag aaaaatcctt ctcagatagt ctttggtggg ctcttgtaac
    10741 ggtaacgact gttggatatg gggatattgt tcctgcttcc atttttggga aatggctagc
    10801 agttttactg atgcttgtcg gtattggaac aatagggatg ttaacaagtg ctttgacgaa
    10861 cttttttgta aaggataatc cagatgaaca gataaaactt gataaactcc aagatgaatt
    10921 atctagtcag agaatattac tagagaaaca atctaaaaag atagaagaac tacataaaat
    10981 gatacaagat ttgattgaaa aaacataata aaaataaaga tgagaaaaag tttgaactga
    11041 ggagaaatca agtaagtttt gacacaatag aacgcatatt atcaggtata aaaacttgat
    11101 actatgcgtt ttatagagaa ataaaataaa atctgaacaa atcaattagg aatttaaagc
    11161 attttataac aacgttttag agtgatgggg tgctatttca acttcaacct actataatac
    11221 agaaaaaaac aactccctga tgattcaagg agttgtctat agttaaatta gtttttagaa
    11281 gcttcttgga attctggatt tttccatgct tcgtcaataa tagcttgcaa ttctttagca
    11341 gatgcttgca ttttttgagt ttctgcatcg ttcaatggaa tgtttactgg acgaatgata
    11401 ccatgtgcac caacaacagc tggttgaccg ataaagacat tctcaactcc gtattgacct
    11461 tcttggaata ctgaaagtgg aagtactgcg ttttcatcgt caaggattgc tttagtgata
    11521 cgagcaaggg ctactgcgat accgtagtat gttgcacctt ttttgttgat gattgtgtag
    11581 gctgcatcac gaacaccttc gaacaattca atcaattcag cttcttgaac attttgagtg
    11641 tctttaagga attcttcaag gtttacacca gcgatgttag cgtgtgacca aacagcgaac
    11701 tcagagtcac cgtgttcacc catgatgtag gcgtgcactg aacgagcatc cacatccaat
    11761 ttttcagcaa gtgcttgacg gaaacgagct gagtcaagtg aagtacctga accgataacg
    11821 cgttctttag ggaaaccaga gaatttccaa gttgagtaag tcaaaacgtc aactgggtta
    11881 gcagcaacaa ggaagatacc tttgaaacca gattcaacaa cttgagttac gattgatttg
    11941 ttgatagcaa ggtttttacc tacaaggtca agacgagttt cacctggttt ttgaggtgca
    12001 cctgcagtga tcacaacaag gtcagcgtct gcacagtcag agtattgagc tgcatagatt
    12061 tttttaggtg aagtgaaggc aagggcgtga ctaaggtcaa gcgcatcacc aacagctttt
    12121 tcatgcaatt gtggaatttc gataattcca agctcttgtg caattccttg gttaacaagt
    12181 gcaaaagcgt aagatgaacc tacagcacca tcaccgacaa ggataacttt tttgtgttgt
    12241 ttagttgaag tcattgtttt aaacatctcc ttaattttat taggggattt tccctagaca
    12301 acttcattct atcactttta aaaaactttg tcacgaatat gccttatagt tctcgatgta
    12361 aacgttttag tggtttagag gctgaaatag atgggaattt atggtataat gttgttactt
    12421 actaattgtg aaatgaggca tttattaatg caggataaaa atttagtgaa tgtcaatctg
    12481 acaaaggaga tgaaggcaag ttttatcgac tacgccatga gtgttatcgt agcgcgagct
    12541 cttcctgatg ttcgagatgg cttaaaacct gttcaccgtc gcattctcta cggaatgaat
    12601 gaattgggtg tgaccccaga caaaccccat aaaaaatctg ctcgtattac aggggatgtc
    12661 atgggtaaat atcacccaca cggggattcc tctatttatg aagccatggt ccgtatggct
    12721 caatggtgga gctaccgtta catgcttgta gatggtcatg ggaattttgg ttccatggat
    12781 ggagatagtg ctgccgctca acgttatacc gaggcacgta tgagcaagat tgctctggaa
    12841 atgcttcgtg atatcaacaa aaatacagtt gatttcgttg ataactatga tgccaatgaa
    12901 cgggaaccct tggtcttgcc agcgcgtttt ccaaaccttt tggttaatgg agcaactggt
    12961 atcgcggttg ggatggcaac caatattcca cctcataatc tgggtgaaac cattgatgca
    13021 gtgaagttgg tcatggataa tcctgaagtg actaccaagg acttgatgga agtcttgcct
    13081 ggaccagatt ttccaactgg tgctcttgtc atggggaaat caggtatcca taaggcttat
    13141 gaaacaggta aaggttcgat tgtcctacgt tctcgtacag agattgaaac gactaagact
    13201 ggtcgtgagc gcatcgttgt aacagaattt ccttacatgg tcaataaaac caaggtgcat
    13261 gagcatattg ttcgcttggt tcaggaaaaa cgcattgagg gtatcacagc agtacgtgat
    13321 gagtcaaacc gtgaaggtgt tcgatttgtt attgaagtca agcgcgacgc ctcagccaat
    13381 gttattctca ataacctctt caaaatgacc caaatgcaaa ccaattttgg tttcaatatg
    13441 ctcgctatcc aaaatggtat accgaaaatt ttgtctcttc gtcagatttt ggatgcttat
    13501 atcgagcacc aaaaagaagt ggttgttcgt cgtacacgtt ttgataagga aaaagcggaa
    13561 gcgcgcgctc atatcttaga aggtctcttg attgcgctag accatatcga cgaagtgatt
    13621 cgtatcatcc gtgctagtga aacggatgcg gaagctcaag ctgagttgat gagcaagttt
    13681 aagctttctg aacgtcaaag tcaagctatc cttgatatgc gtcttcgtcg tttgacaggt
    13741 ttggaacgcg ataagattca atctgagtat gatgacctct tggctctgat tgcggattta
    13801 gcagatattc ttgctaagcc tgaacgtgtt tctcaaatta tcaaagacga attggatgaa
    13861 gttaaacgta aattttctga taaacgccgt acagagttga tggttggaca gatcttgagt
    13921 ctcgaggatg aggacttgat tgaagaatcg gatgtcttga ttaccctttc taacagaggc
    13981 tacattaagc gtttggatca ggacgagttc actgctcaaa aacgtggggg tcgtggtgtc
    14041 caaggaacgg gagtgaaaga tgatgacttt gttcgtgagt tagtgtcaac tagcacacat
    14101 gatcatctgc tcttcttcac aaacaaggga cgtgtctatc gtcttaaagg ttatgaaatt
    14161 cctgagtatg gtcggactgc caaagggcta ccagtagtca atctcttgaa attggatgaa
    14221 gacgaaagta ttcagacggt tatcaatgtt gagtctgatc gcagtgatga tgcttatctc
    14281 ttctttacaa cccgtcacgg tattgtgaag agaactagtg ttaaggagtt tgccaatatt
    14341 cgtcaaaatg gtctcaaagc gctgaattta aaggatgaag atgagttaat caatgtcttg
    14401 ttggcagaag gagatatgga tattatcatt ggtaccaagt ttggttatgc agttcgcttt
    14461 aatcaatcag ccgttcgtgg tatgagccgt atcgccactg gtgtgaaagg tgttaacctt
    14521 cgtgaaggag acacagttgt tggtgccagc ttgattactg atcaagatga ggttcttatt
    14581 atcacagaaa aaggatatgg taagcgtaca gtcgctactg aatacccaac aaaaggtcgt
    14641 ggtggtaagg gaatgcagac agctaaaatt accgaaaaaa atggcttgct ggccggtctt
    14701 atgactgttc aaggggatga ggatttgatg attatcactg atacaggtgt catgattcga
    14761 accaatcttg ccaatatttc acaaacagga cgtgcaacta tgggagttaa agtaatgcgc
    14821 ctggatcaag atgctcagat agtgactttc acaacggttg cggtggcaga aaaagaagaa
    14881 gttgggacag aaaacgaaac agaaggtgaa gcataatgtc tcaaaaaaat aataaaaaga
    14941 aaaacaagcg aaaaaatctg ctgacaaata tcctagcagg atttctgata ttactgtcac
    15001 tggctttgat ttttaatact caaattcgaa atattttcat agtctggaat accaataagt
    15061 atcaagttag ccaggtatca aaagaaaaat tagaagaaaa tcaggataca gaaggcaatt
    15121 ttgactttga ttctgtcaaa gctatctctt cggaagctgt tctaacttct caatgggatg
    15181 ctcaaaaatt accagttatt gggggaattg caattcctga attggaaatg aatttgccga
    15241 tttttaaagg acttgataat gttaatctct tctacggagc tggtacaatg aaacgcgagc
    15301 aagtaatggg agaaggaaat tatagtctag ctagtcacca tatctttggt gttgataatg
    15361 ctaataaaat gttattttct cctttagata atgctaaaaa tggcatgaag atttatctaa
    15421 ccgataaaaa taaagtttat acttatgaaa tacgtgaagt caaacgtgtg acaccggatc
    15481 gtgttgatga agttgatgat agagatgggg tcaatgaaat cacattagta acctgtgaag
    15541 accttgctgc tacagaacgt attattgtca aaggtgattt gaaagaaaca aaagattatt
    15601 cacaaacatc tgatgaaatc ctaacagctt tcaatcaacc atataaacaa ttttattaat
    15661 acaaatcagt gaaatcatgg atttcactga ttttttaaga ttttcataaa aatatagtaa
    15721 aatgaaataa gaataggacg aatcg
//
LOCUS       DAVHSL010000050        14125 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000050 DAVHSL010000000
VERSION     DAVHSL010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14125
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.052"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            81..878
                     /locus_tag="VVR39_001685"
     CDS             81..878
                     /locus_tag="VVR39_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU6031119.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VVR39_001686"
     CDS             1026..1148
                     /locus_tag="VVR39_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEU6031120.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            1170..2210
                     /locus_tag="VVR39_001687"
     CDS             1170..2210
                     /locus_tag="VVR39_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU6031121.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2381..3655
                     /locus_tag="VVR39_001688"
     CDS             2381..3655
                     /locus_tag="VVR39_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU6031122.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVRHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VVR39_001689"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VVR39_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU6031123.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERSERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VVR39_001690"
     CDS             4784..5086
                     /locus_tag="VVR39_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6031124.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VVR39_001691"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VVR39_001691"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU6031125.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VVR39_001692"
     CDS             5960..7300
                     /locus_tag="VVR39_001692"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU6031126.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEVKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VVR39_001693"
     CDS             7278..7490
                     /locus_tag="VVR39_001693"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU6031127.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VVR39_001694"
     CDS             7487..8362
                     /locus_tag="VVR39_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU6031128.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VVR39_001695"
     CDS             8355..9170
                     /locus_tag="VVR39_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU6031129.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VVR39_001696"
     CDS             9163..9594
                     /locus_tag="VVR39_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6031130.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VVR39_001697"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VVR39_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU6031131.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VVR39_001698"
     CDS             11270..11998
                     /locus_tag="VVR39_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU6031132.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VVR39_001699"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VVR39_001699"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU6031133.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13981..>14125)
                     /locus_tag="VVR39_001700"
     CDS             complement(13981..>14125)
                     /locus_tag="VVR39_001700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031134.1"
                     /translation="FEVVDETDEVSSKHGFEIVDETDEVSNHTYGKATLTWFEEIFEE
                     YKN"
BASE COUNT         4175 a         2582 c         3363 g         4005 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cagaatttat ttcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatat
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgat acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaatga tatggaggtc
     1021 accttatgac ttgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatctttt atttttgatg
     1141 acacgtagga aggtgctgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatgttgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaactc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaatacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc
     1741 acaatttgag ttatacttgt gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac ctcttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttgc caaaagatgt cggttcaatc tttaccttcc
     2041 atgtcaaagg tggcgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 atcttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaactaa attcgtttgt
     2221 caatcggtct tgaaaatgta gaagatttga ttgaagactt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggct tcgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttaaaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc
     2521 tgagcaaaag gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt
     2641 tgaacagaca agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa
     2701 tcagttggct accttgcgtt tggagcatga aaatcaactg caaaagaccc tttctgacct
     2761 agaaaaagaa cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt
     2821 atctttggct tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt
     2881 cgagttttat aaggatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcagacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gccgataatg actactttaa
     3241 cacagggatt gttgacgtca gacacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagatttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggcggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aatcactctg ggctattcca cgacgactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgttcagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga tgctcttacc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagatgctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg tagatactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa cttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aaacggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgcatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ttatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc tgccccaatt
     6361 ttctaagaga attggggtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atggtaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggtcaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttaccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agactcatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagattaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctttgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgccct
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agattccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag gttcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attgccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgaactatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gatctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagcc atgaatgaca tggaaagtgt cgaagagtat
    10381 gaccctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctcatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaataaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acggtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc ttaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtccgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcggcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atctttgttc acgcaggtat
    11701 tgatttgacc ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacaggaga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg aaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttattcagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taagaatcaa tagtaatgca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aatctcaaaa ccatgttttg agctgacttc
    14101 gtcagtttca tctacaacct caaaa
//
LOCUS       DAVHSL010000051        13963 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000051 DAVHSL010000000
VERSION     DAVHSL010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.053"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            82..279
                     /locus_tag="VVR39_001701"
     CDS             82..279
                     /locus_tag="VVR39_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6031135.1"
                     /translation="MAGKITKKSSSMGIIANVFAGLVGAYAGQSLLGSWGPSIAGMAL
                     LPSIVGAAIVITVVSFFTGRK"
     gene            363..929
                     /gene="amaP"
                     /locus_tag="VVR39_001702"
     CDS             363..929
                     /gene="amaP"
                     /locus_tag="VVR39_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU6031136.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            941..1111
                     /locus_tag="VVR39_001703"
     CDS             941..1111
                     /locus_tag="VVR39_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU6031137.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1150..1758
                     /locus_tag="VVR39_001704"
     CDS             1150..1758
                     /locus_tag="VVR39_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6031138.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1789..1992
                     /locus_tag="VVR39_001705"
     CDS             1789..1992
                     /locus_tag="VVR39_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6031139.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLHKEEK"
     gene            complement(2065..2511)
                     /locus_tag="VVR39_001706"
     CDS             complement(2065..2511)
                     /locus_tag="VVR39_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031140.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            2581..3240
                     /locus_tag="VVR39_001707"
     CDS             2581..3240
                     /locus_tag="VVR39_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU6031141.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(3292..4443)
                     /locus_tag="VVR39_001708"
     CDS             complement(3292..4443)
                     /locus_tag="VVR39_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6031142.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESVRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLSLKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(4458..5187)
                     /locus_tag="VVR39_001709"
                     /pseudo
     CDS             complement(4458..5187)
                     /locus_tag="VVR39_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5416..5517
                     /locus_tag="VVR39_001710"
                     /pseudo
     CDS             5416..5517
                     /locus_tag="VVR39_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(5489..6265)
                     /locus_tag="VVR39_001711"
     CDS             complement(5489..6265)
                     /locus_tag="VVR39_001711"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU6031143.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQV
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(6258..7481)
                     /gene="trpB"
                     /locus_tag="VVR39_001712"
     CDS             complement(6258..7481)
                     /gene="trpB"
                     /locus_tag="VVR39_001712"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6031144.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEYHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(7459..8058)
                     /locus_tag="VVR39_001713"
     CDS             complement(7459..8058)
                     /locus_tag="VVR39_001713"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU6031145.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(8045..8812)
                     /gene="trpC"
                     /locus_tag="VVR39_001714"
     CDS             complement(8045..8812)
                     /gene="trpC"
                     /locus_tag="VVR39_001714"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU6031146.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGTVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKKLYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(8809..9813)
                     /gene="trpD"
                     /locus_tag="VVR39_001715"
     CDS             complement(8809..9813)
                     /gene="trpD"
                     /locus_tag="VVR39_001715"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU6031147.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9824..10390)
                     /locus_tag="VVR39_001716"
     CDS             complement(9824..10390)
                     /locus_tag="VVR39_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU6031148.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(10387..11748)
                     /gene="trpE"
                     /locus_tag="VVR39_001717"
     CDS             complement(10387..11748)
                     /gene="trpE"
                     /locus_tag="VVR39_001717"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU6031149.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(11883..12038)
                     /locus_tag="VVR39_001718"
     CDS             complement(11883..12038)
                     /locus_tag="VVR39_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031150.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            complement(12250..12327)
                     /locus_tag="VVR39_001719"
                     /pseudo
     CDS             complement(12250..12327)
                     /locus_tag="VVR39_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12935..13936)
                     /locus_tag="VVR39_001720"
     CDS             complement(12935..13936)
                     /locus_tag="VVR39_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6031151.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         4048 a         3029 c         2506 g         4380 t
ORIGIN      
        1 aaattgattt tttgatatta aaataaaaaa ggagggtagg cagtgttgtg atcaattatt
       61 gctggaggtc ttattggtct cttggcaggt aaaatcacta aaaaaagtag ttctatggga
      121 atcatcgcaa atgtattcgc tggtttagtc ggggcatatg caggacaatc tcttttaggt
      181 agttggggtc catcaatcgc tggaatggct ttgctcccat ctattgtagg tgcagcgatt
      241 gtgattactg tagtgtcatt ctttacaggt agaaagtaaa cttttcgcca gtaaagttag
      301 caaactattt ttaaatcaat gacgggaaaa atagtttaaa tgttaaatcg aaaggattgt
      361 atatgtcaaa agcaaagaaa atatgtttca ttattttctg tattttaatc ttgacaattt
      421 tccttcctgt tttgatagat tatcatcaag ttagtgatct aggtattcat ctacttagct
      481 ggagacagaa ctccgtagtt gaattctatc ttgctagata tgtcttttgg gggacagtgg
      541 ttctatcaac tttagtttta ttatccattt tagttgtgat gttttatcct aaacgttact
      601 tggaaatcca acttgaaact aaaaacgata cattaaaatt aaagaattcg gcaatcgaag
      661 gttttgttag aagtttggtg agtgatcata gattgatcaa gaacccaact gttcatgtaa
      721 atttacgaaa aaataaatgt ttcgttcatg tagaaggtaa aattcttcct tcagacaaca
      781 tcgctgacag atgccaaata attcaaaatg aaataactaa tggattgaag cagttttttg
      841 gtattgagcg tcaagtaaaa cttgaagttg cagtaaaaaa ttaccaacca aaacctcaaa
      901 acaaaaagac tgttagtcgt gtgaagtaag gaagtaaaaa atggaatggc ttaaacaata
      961 tcgatatcca attatcgctg gtctcatagg cgtatttctg gcttgtttga ttgtctcctt
     1021 tggcttcttc aaaacaatat ttgtattgat tttaggagca ctgggagttg cagctggatt
     1081 atatatcgaa aaaaactata tagataaata aaaaaataaa aattactaat ttaattaaag
     1141 gagtttcata tgtcaaacga aaaaaacaca aacactaacg tagaaaagaa agatgctact
     1201 gttgtagctc acgaaatcaa aggggaactt acttacgaag ataaagttat ccaaaaaatc
     1261 attggtcttt cactagaaaa cgtttcaggt cttttgggaa tcgatggtgg tttcttctca
     1321 aatcttaaag aaaaaatcgt taacagcgat gacgtaacaa gtggtgttaa cgtagaagtt
     1381 ggtaaaacac aagttgcagt tgacttaaac gttattgttg agtaccaaaa aaatgttcca
     1441 gctttatatt cagaaatcag agaaatcgta tcttcagaag ttgctaaaat gactgacttg
     1501 gaaattgttg aaatcaacgt aaacgttgtc gacatcaaaa ctaaagaaca gcatgaagca
     1561 gactcagtaa gccttcaaga tcgcgtatct gacgttgctg aatcaacagg agaattcact
     1621 tcagaacaat tcgaaaaagc taaatctggt cttggatctg gtttctcaac tgttcaagaa
     1681 aaagttagcg aaggtgtaga agctgttaaa ggtgcagcaa atggtgtagt atctcacgaa
     1741 aacactcgtg taaactaaga taaaataaat ataacaggag aaattatcat gtcagtagaa
     1801 gaaaaattaa atcaagctaa aggttctatt aaagaaggtg ttgggaaagc catcggtgat
     1861 gaaaaaatgg aaaaagaagg agcagctgaa aaagttgttt ctaaagtaaa agaagttgcc
     1921 gaagacgcta aagacgctgt agaaggtgct gtagaaggtg ttaaaaacat gcttcataaa
     1981 gaagagaaat aaggtttaga ctttatatat tcttttaaga ccaaaaaatc aggaaaagcc
     2041 ttggaatcaa ggcttttttg atgtttatct cccctttttc atgatgtatt ttcgtacagg
     2101 tgcttcaacc atttgaacga tttcaaatcc ttctttttgg taaagattct gagctctttg
     2161 atttgcctcg aagacattta gagaaatact atctatatct tcattttcaa aggccaaact
     2221 aacaaatttc cttaaagcct ggctacctaa gtcttgctcc tgcttctggg ggttgataaa
     2281 aaatctcccg atatgaagat tgctgtcttc tagcctgatt ttctggataa gtcccacaaa
     2341 ctcttgttca tcaaagattg aaaagactcc ttccaaggct tgaagggtca gtagaaaagg
     2401 aatccttggt cccatccatt gttcttgaaa gactttgcct aaggagttgg accattggca
     2461 tacgagctga gcgttttcta tactcacctt ttcttcaaaa cgaattgtca tcttttcctc
     2521 accatcttat ctatgtttct ccattatact atttctccca ttttttacga atagataagt
     2581 atgattgatt tttatttttt tctcgtcggg agcattctcg cttcctttct tggtttggtc
     2641 attgaccgtt ttccagagca atccattatc agttcagcca gtcactgcga ttcctgtcag
     2701 actcgcttgc gtcccttaga tttgattccg attctctcac aggtcttcaa tcgctttcgc
     2761 tgtcgctact gcaaagttcg ctatcctgtc tggtatgccc tctttgaact aggcttagga
     2821 ctcctctttc tgctttactc ttgggaattg ctttccttgg ggcaagtcgt cctaatcacc
     2881 gctggtttga ccttgggtat ctacgacttt caccatcagg aatatccctt actggtctgg
     2941 atgactttcc acctaatcct aatagcttcc tctggctgga atctggtcat ggtctccttc
     3001 ctcatacttg gaattttggc tcattttatt gatatccgca tgggtgcagg ggatttcctc
     3061 tttttagctt cttgtgctct cgtctttagc gtaacggagt tactgatctt gattcagttc
     3121 gcttctgcga cgggtatcct ggcctttctc ctgcaaaaaa aaaaggaaag acttcctttc
     3181 gtgcctttcc tcttacttgc tacttgtttg attatttttg gtaagctact gcttgtttga
     3241 taaattccaa tttctgccat atgtccttca tgaaattatt tcacagttaa attataaatt
     3301 atttcttttg tacaaaggga tgatgttatc aaatcgatct gttcttctat cttcttgata
     3361 ctgatcaaaa aatttcattt cgactgaaaa tatttcgctt ataaactgta aacgaatact
     3421 ttgtttagac attatagtcg ctagactgac tagatgatta ctcaaaacga cgtccagaat
     3481 actctttact ttgcttggtt ttttaacaaa aatttgatca tccaaaggtt caatcatttt
     3541 gtaacctttt tgcgcaattt gacgataaaa gtaagaatgt tgctttagag acaataatcc
     3601 taacttaaaa gctcgatact ctaaagcctg tatcgaaaca ttcaaatccg acttcaataa
     3661 aatataacta tcaggattgc tgacacgctt gccaaccctc tcttcaaatt tgactaaaaa
     3721 ctcttctttt ggcaataaaa aacatgatgc aaaataattt gcttcttgct ccaaacgatc
     3781 gccatcttca ttcatatctt tatatttatg taaaagaata tgtcctagct catgagctaa
     3841 gtcaaaattt cgacgtacag atgatttatt cgttcccaac acaatataag gtcttcccaa
     3901 ttttgaccat gcgctataag catcagcttg gccattaatt aatcgttcca cgatatagat
     3961 gcctgaacgt tctaatttat aaagcaaatc atgattatct tttgaaatac ctaatttttc
     4021 cctggcataa agagccaatt cctcaatgga ttctccctta tgataagatt cactcactac
     4081 attacttaag tcatgaattg taatattagg tataattaca aaactttcaa aataatcaat
     4141 caaactatct accttatgta aatacatagt ttgaatatct attgttttcc gtgttgctag
     4201 gtctgcattt ctaaaggcaa ttacagaaga atcaaatcga acgctctctt cttcctgttc
     4261 aaaataagtt aaatcaacat gaaattggtt ggccaaatgc attttggttg ataatttagg
     4321 tttcgtttcg ttggactcaa actgccaaat ggcttgttcc gttaaattaa ttctctgagc
     4381 taattctgct ctacttaaac catttaacag ccgtaattct ttcaataccc gaccattaaa
     4441 catttacata ctccttacta cttttgacct tcttgttttt ctattcttgg aataatttca
     4501 aaatcttctg tttccgataa ttctgaaaaa ttaggaatat cttgatattt agcttcttcg
     4561 aaatggtacg aacttgattg aatatactca gacaaatctt gaatcaagtg taactgacca
     4621 gttcgtgcat caggcataac aacatctaca gatataatat tgttttctga gtccgcctca
     4681 taagttaaaa tcataaattt ttcgatattc gaatttttag tagcttgttc aatttcttga
     4741 atcatttcat cagaaactaa ctccatctga attggaaagg aatgactatc ttcatcattt
     4801 ttgtaggaag aatgttgatt aagataaagt gtattcatct gagcatattc aaataagtag
     4861 ccactcttat ttttttgtac caaaggaaat tggttcgtaa gtcgcttctt accctttata
     4921 attaacaata ctttcccata tttttctgtg tttgtttcaa attctaaata tccaagtctg
     4981 tcctgctaat tgtaatttat actcaaacaa atctgctgat gcaaatgcag tatcaatatg
     5041 attaggtcgc gtccatgcat aaccattcga cactatcatt gtctctcttt tttctagacg
     5101 ttcatctaca taatcttttt gccctttcat caaagtatct acaatttttt gtgcctcaag
     5161 cgaatcaaag agatcctgat tcaacataat tcttcctcct ccaaatactt tttaatgaat
     5221 tatatcattt tcttaaagaa attactacaa taattagctt tttcttaaag ttctgtgtca
     5281 gagtaattta gaaaattata tcttctatag taaaatcaat taaaaactga acaaatttat
     5341 tgggaaattc aaatcgcttt ctgaaaatat tttaggaacc gtagtgtaat attccagatt
     5401 caattcacta taaaactagc ctttctcctg caaaagaaaa aggaaagact tcctttcgtg
     5461 cctttcctct tacttgctac ttgtttgatt atttttggta agctactgct tgtttgataa
     5521 agtcctgaat cggctctcct tggtggagag cttttactat tttcgaaccg acgataacac
     5581 catctgacac cgcattgaag cgttccagat cgacttgact agatacacca aaacctgtca
     5641 agactgggat gtcggccact tgatgaagtt gcgccaagtg cttgtccaaa tctgcacggt
     5701 aattgcctga tttccctgtt accccattga tggcaacggc atagacgaat ccctccgccc
     5761 cttcaatcaa ctctttctgg cgctcaattc ctgtggtcaa gcttactaaa ggaatcaagg
     5821 cgatatctgt atctgccaaa aatggttcta caaagttggc atgttcatga ggcaggtctg
     5881 ggataatcaa gcccttcaca gctgtatcag ccagatcttt gacaaagttc tccacaccgt
     5941 actgaaagag ggggttgaag taggtcatga tgaccagtgg aatctctgtt tcaatggttt
     6001 tcaaggtttc aactaaagcc tgggtagagg tcccgtgggc taaactgcgc aagccagctt
     6061 cttcgataac aggtccatct gcaacagggt ctgaaaaggg aatacccact tcaattgcag
     6121 agacacccaa atcttctaaa aagtgaattg tttcagcaag accatccaaa cctttttcgt
     6181 ggtcaccagc catgatatag ggaacaaaaa ttccttttcc agctgcttta atagcattta
     6241 atttttttgt tagtgtctta ggcatgagct tctcccttct ttgctgcatc tgcttccaag
     6301 cggtccttga cttgaaccac atccttgtcc ccacgacctg ataggcagac aatcatagac
     6361 ttttctggtc caagttcttt ggccaatttc accgcaaaag cgatagcatg gctagattcc
     6421 aaagctggga taatcccttc cacacgagac aagagttgga atccttccaa ggcttcttcg
     6481 tctgtcacag ggacatagct ggcacgttta atatcgtggt agtgagaatg ctctggaccg
     6541 ataccaggat agtccaaacc tgctgagata gagaaggctt caagaatttg accatgggca
     6601 tcttggagca catccatgag ggaaccgtga aggacacctg gacgaccctt ggtcaaggta
     6661 gctgcgtggt actccgtatc cacaccaaat ccagccgctt cagctccata catggctact
     6721 gactcatctt ctacaaaggg atggaagaga ccgatggcat tcgacccacc accaacacag
     6781 gctactaggg catctggcag attttgtcct gtcaagtcac ggtactgttg tttagcctct
     6841 cgaccaatga cactttggaa gtcacgaaca atttctggaa atggatgagg ccccaaggca
     6901 gaaccaagga tatagtgggt atcatctata ttagccaccc atgaacgaag ggctgcattg
     6961 accgcatcct tgagcacgcg cgaaccatct gtcacggcct cgaccttagc tcccaaaagc
     7021 tccatacgga agacattgag ggcttggcgt ttgacatctt cctcacccat gtagatggta
     7081 cattccatgt taaagagggc cgcagcagtt gcagttgcca caccgtgctg accagcacca
     7141 gtttctgcga taattttctt tttacccatg cgtttggcaa gccaaacttg tcccaaggca
     7201 ttgttaatct tgtgggctcc tgtatggtta aggtcttccc gtttgagata aatcttggct
     7261 ccgccgatat gctgggtcaa gttttttgcg tagtaaaggg gagtttcacg tcccacgtac
     7321 tggcgcaaaa gctggtttaa ttcctcttgg aaacttgggt ctgcctgact ttcacggtag
     7381 gccttctcca actccaaaac tgctgtcatc aatgtttctg ggacaaaacg tccgccgaat
     7441 tttccgtaaa atccatcttt atttggttcc tgatatgcca tgctttaccc tctctataaa
     7501 tcttctaatc ttttcatgat ctttttgtcc atctgtctcc actccgctcg atacatctac
     7561 tgcataggga gtaaaatgtt gaattgcttt tactacatta tcttcattaa ggccacctgc
     7621 gataaagaag ggctgtgcta gtccagtcgt atccagttga ccccaatcaa agggctggcc
     7681 acttcctgcc acaggggcat caaagagtag ataatctgcc tgagaattgg ggacatgccc
     7741 atttccatct acctgcacag cctgaatact ggcacaaggc aaattctcaa ataaatcatc
     7801 tgccacctga ccgtgaactt gaaccaagtc caagccaact ttgtcaatcg cttccagcag
     7861 ttctacccga cttggtgaaa caaatactcc aacctttttc acatctgcag gaataagctt
     7921 tgccaactca gctgcctctt ctaaagtcac ctgtctttta ctaggtgcaa agacaaaacc
     7981 gatatagtcg gctcctgctg aaacggctgt ttccaccgct tctttggtcg atagtccaca
     8041 aattttaacc tttgtcaatc tgcaactcct tgattctctg ggccacattt tctgcctgca
     8101 taagagctgt ccctaccaaa attccgttaa agtatggggc tagtcgttcc gcatcctgcc
     8161 ctgtgaaaat ggcagattca gaaatgtaat agcgaccttc ctcaaagtaa ggggctaaat
     8221 ctacactggt ctgcaagtcg acctcaaagg tagtcaagtt gcggttgttg accccgataa
     8281 tctcagcacc aagtctgtgg gctacctcta gttcagctag attgtgagtt tccaccaaga
     8341 cttccagacc aagctctgtc gcgtagtcat acagtttctt gaggcgttct tcggacaagg
     8401 ctgccacaat aagcaagata actgtcgcac ctgcattgcg agcgcggatg atttgctttt
     8461 catctatgat aaagtctttg ttgagcgtcg gaatctctac ctgactggaa atctcccgta
     8521 gataattcaa atgcccttta aagaaaacct catctgtcaa caccgaaatc atcactgttc
     8581 cgttttcttc ataagtctgg gcctgttgca caatatccac atcgagattg atatctccca
     8641 aactagggct agctttcttg acctcagcga ttacctgcaa gcggtcctga tgattcttca
     8701 aaaattctgc caagcgatag gtctggcgca gaggctggat ttgctccagc ttcatctgct
     8761 ccacctcacg cgccttctgc tctaagattc gtgctaaaaa ttcctgactc atttttggta
     8821 ctcctgtaac agtctgagtt tttcaagggc cttgcctcta gcaatcactt gacgggccaa
     8881 ggcaactcct tccttgatgc tatcaatctt accattagca tagaaaccaa gaccagcatt
     8941 caagactgtc gtttccaaga atggacttgc ttcgtttttc agaacgctaa gcaaaatttc
     9001 tgcattttcc tgagcattcc caccacgaat atcttccata gcatagcctt ccattcccaa
     9061 atcctctgga gtaaagcttg acaagctgat ttcgccattt tcaagaagtg caatcttggt
     9121 tgttccgttc aagccagctt catccaaccc ttctggtcca gcaaccacga tggcacgttt
     9181 gcgacccata tttttcaaaa cctgagctgt actttctagg agttctggac gactaattcc
     9241 aagaagctgt gtttctaaag ccattggatg aatcagtgga ccagtcaagt tcataatcgt
     9301 tggaattccc aattccaaac gagctggcat gatgtatttc atagctgggt gcatattttt
     9361 agcgaagaga aagacgattc cagttttatc aaagacctta cctagttcag ctggtttgag
     9421 gtcaagattg attcccaagg cttcgaggac atctgcggaa ccagatttag aagatatcga
     9481 gcggttaccg tgtttggcca tgtgaatacc gccaccagcc aagacaaagg ctgcagttgt
     9541 ggaaatatta aaactgaaag acttgtcccc acctgtacca cagttgtcca tggcatcatg
     9601 aatctcagtt ggaatatgct gggcatgtcc tctcatgact tgggcaatgg ctgtgcgttc
     9661 ttcaggtgtt tcccccttca tcttaagagc taagaggaga gaagcaatct gcgcttcagt
     9721 tacacgccca gttacgatac gctcaatgac atccgtcatt tccacacctg ataaattttc
     9781 aaattttgct agtttttcaa taatctcttt catcctagtt tcctcacttt acaacctcct
     9841 cgataaaatt ccgaatagaa gacaagccgt ctggcgttcc aatgctctct ggatggtact
     9901 ggaagccata aatcggtagg tttttatgtt gaatccccat gatggcttgg tcatcagtcg
     9961 aacgagctgt cacttcaaag tcttctggca tttcctcaat caaaatactg tgataacgca
    10021 tgaccgcacg tccatcctca ataccttgat acaaaacaga tggcgcttca aagttgatat
    10081 tgctctgttt cccatgcatg acttttggag ccaaacctag cttaccacca aagacttctg
    10141 caatggcttg gtggcccaaa caaatcccta gaatcggctt cttgcctgca aaatcacgaa
    10201 tcatgtcttc catctttcca gcatcaactg gccaaccagg accaggagaa aagaccagac
    10261 catctgcttt ttcagcttct tcatacagct tggaatcatc atttctcaga acctgaactt
    10321 ctgcaaaatt cccaatgtat tgggccaagt tataggtaaa agaatcatag ttgtcaatca
    10381 ataaaatcat ggtcttagtt ctccaattct agtcatagat tttgctttgt taatggtttc
    10441 ttggtattcg ttttgggcga tagagtcgta gacaatccct gccccagcct gcacataggc
    10501 tctttgattt ttgagaatca tggttcggat ggcaatggcc aaatccatat cacccgtcgc
    10561 agacaagtag ccgattgctc ctgcatatac gccccgtttt tccgtttcca gttcatagat
    10621 gcgtctcatc gcccgaatct ttggtgctcc agaaacggtt ccagcaggaa gtgtagcttt
    10681 caaggcatcc atggccgtga gttctgcaag caaacgcccc ttgaccacgc tggtcaaatg
    10741 catgacgtag cggaagagct ccaccttcat atacttagta acttggacac tggccgtttc
    10801 agagatgcgg ccaatatcgt tacgccccaa gtctaccaac attcgatgtt ctgctgtttc
    10861 cttctcatca gagaggaggt cagtcgccaa ggtcttgtct tcttcatccg tagcccctct
    10921 tggtcgcgtc cctgcaatcg gattggttgt cacgatgcca tttttgacag aaactaaact
    10981 ttctggacta gctccgatga tttgataatc cccaaaatca tagaaataaa ggtaattaga
    11041 aggattagtc acgcggagat ttctgtagaa gtcaaatgga tttccagtaa cttctgctga
    11101 gaaacgctgg ctgagtacac attggaacat atcaccatta cgaatcaagt cacgagctgt
    11161 ttctaccatt acctcaaact tatgtggagc gatatgcggt ttgaagtcaa gtggtgataa
    11221 atccaagtct tcaaattcat ttggagcagg aatgcgtaat tcctcaagca cttggttcaa
    11281 ggatttttcc aaggcctctt gactgcgctc actatagaga gcatcctcta tgacatgtat
    11341 cttctccttc ttgtggtcaa agaccatata gctctcatag acaaagaaat gcatgtctgg
    11401 cgtcccaatt gtatcctcag ggatttgacc aatttcttca taaagcgaaa tcatatcgta
    11461 acccacaaaa ccaatggctc caccaccaaa cgggagctct gagtggtgct gactcttatg
    11521 aatcacttca taaaggaaat ccaagggatc ccgatcaatc acttgaccat tttgatagag
    11581 aactccattt tcaaacttaa tctcaaaaac tggattatag gctaggatag aaaaacgagc
    11641 tgtttccttg tctctcggaa tactctctaa aataaccttg tgttgcccct ttaagcgcat
    11701 gtaagccaag attggtgata agacatctcc atgaatgatt cgttccattg taatttccct
    11761 ttcagttcta cttatagtcc gtagcgactg tatgaaaaat ccccacgcaa aataacttgc
    11821 gtgaggacga aattcgcggt gccacctcaa ttataggatt tctcctatct ctcattcctg
    11881 tctcagatat ctcctgtaac aggctgtgcg ataaagggca ctcccttgag aatgatgttt
    11941 tcttctctcg tttcagatga acccaacttt acagctttct ctgcttgttt ccagcaacca
    12001 caagctctct gtgagagaaa gaactgtaat ttttccatct attatttttt agcttctagg
    12061 tagtctgcaa tcgcagctag gtccttgcct ccacgaccag agacattgat gaagagatgt
    12121 tcatctcggt acacctttat actcttcgaa aatctcttca aactgcgtca acgtcgcctt
    12181 tccgtaggta tggttactga cttcgtcagt tctatctgca acctcaaaac agtgttttga
    12241 gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagcagc ctgcggctag
    12301 tttcctagtt tgctctttga ttttcattga gtattactag cttttttcgt attagtccag
    12361 cctttttgtt tgcttttagt agtaggcaag gagctgtaga tagaactcaa gttcatcaaa
    12421 gcgacttaag gccctaataa aagataaacc aaacgacgga tagaaaaaag cccacacaca
    12481 gaatatactt ccgtgtgagg gcgttggtaa cgcggtgcca cctcaattat aaagggacta
    12541 tccctttaca tctctgcctt gtttaacaac aagctgcact gtaaggtgtg cgcaccgaat
    12601 tttcattgtt tcaaattcat tttcaaaatc agcccacttt cactacttcc aaccacctat
    12661 tcacaatcac cacaggctcc ctgaagatca aaaatagtta cttttctgat ttgttgaact
    12721 tattttaata ctttgttttt tctttgtcaa gactttttta cgattttttt gaaaatatca
    12781 ttcgaatgtg accatgtctt ccttagatcg aacatgaaca tgtcccactt gttagaaatt
    12841 ggatccaact caatagaaac tgaatggagg ctaaacagaa cttattttag aacactccat
    12901 cttttccact aggattttca agaattaaac aatactagaa actctgtctc ctaacaaatt
    12961 taggagaaac ttcaacagat gtgacacttt cccctttaat aattgctaaa acaccttcta
    13021 tcatttcttt agccaattta acataattgg gagcaattgt agacaaagct ggagtataat
    13081 actgagaaat aggaatatta tcaaatccaa tgatagaaat atcatctgga ataagaattc
    13141 ctttctcata gcacgcacga atcaagccct gaaccttttc atctcctgaa acaaaaataa
    13201 tgtccggata attttgggta gtcaagtgct gcattgcata agaataaact gaatcaattg
    13261 tagataagcc ataaatgact tttaaatcca taaagtaatt tttatcattc agaaaagaac
    13321 gcacacctct ttcacgatcc ttattaacat gggattctcc tcccataagc aaccacatat
    13381 ttttaaattt ttcttcagtt acagctttca tcatatcata agtagcttga aaattattat
    13441 tagatacata gactactcca gacgtttgag attcaccgaa aacaagaaaa ggcatatggt
    13501 tcttctttaa atactgaatt ctgatatcat ctacactttc ataaaaaaca ataacaccat
    13561 ctactaggct acctgtgctt gatataattg aattactaat tgtatcctcc tctccaaagt
    13621 actcaactat agcattaaca ccaaattctt tacacgtccg taacacttta tctaacagcg
    13681 tatgaaacca aattaaagga aaagagtcga ttttttttac agaaatcaat atatttatag
    13741 cttctttttt agttaaattt tttgcatacg catttggaat atacgacaat tcctctataa
    13801 ctttttgaat cgcttgataa gtttcttctt taacatttac tccaccatta ataactcgtg
    13861 aaactgtttt tggagaaaaa cctgataaac gtgcaatatc ataaatagtt acctttttcc
    13921 catttatatt tttcatttca gtcctccatt acgaacattc taa
//
LOCUS       DAVHSL010000052        13671 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000052 DAVHSL010000000
VERSION     DAVHSL010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.054"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(98..1459)
                     /gene="dnaA"
                     /locus_tag="VVR39_001721"
     CDS             complement(98..1459)
                     /gene="dnaA"
                     /locus_tag="VVR39_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU6031152.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1672..2430)
                     /locus_tag="VVR39_001722"
     CDS             complement(1672..2430)
                     /locus_tag="VVR39_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU6031153.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHTEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2488..3669)
                     /locus_tag="VVR39_001723"
     CDS             complement(2488..3669)
                     /locus_tag="VVR39_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU6031154.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3852..4331
                     /gene="rlmH"
                     /locus_tag="VVR39_001724"
     CDS             3852..4331
                     /gene="rlmH"
                     /locus_tag="VVR39_001724"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU6031155.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4375..4448
                     /locus_tag="VVR39_001725"
     tRNA            4375..4448
                     /locus_tag="VVR39_001725"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4409..4411,aa:Arg,seq:tct)
     gene            4614..4739
                     /gene="comC"
                     /locus_tag="VVR39_001726"
     CDS             4614..4739
                     /gene="comC"
                     /locus_tag="VVR39_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU6031156.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4760..6085
                     /locus_tag="VVR39_001727"
                     /pseudo
     CDS             4760..6085
                     /locus_tag="VVR39_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            6082..6834
                     /locus_tag="VVR39_001728"
     CDS             6082..6834
                     /locus_tag="VVR39_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6031157.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6886..6957
                     /locus_tag="VVR39_001729"
     tRNA            6886..6957
                     /locus_tag="VVR39_001729"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6919..6921,aa:Glu,seq:ttc)
     gene            6963..7036
                     /locus_tag="VVR39_001730"
     tRNA            6963..7036
                     /locus_tag="VVR39_001730"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6997..6999,aa:Asn,seq:gtt)
     gene            complement(7077..7619)
                     /locus_tag="VVR39_001731"
     CDS             complement(7077..7619)
                     /locus_tag="VVR39_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU6031158.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7798..8565
                     /locus_tag="VVR39_001732"
     CDS             7798..8565
                     /locus_tag="VVR39_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEU6031159.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIEKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            8569..8988
                     /locus_tag="VVR39_001733"
                     /pseudo
     CDS             8569..8988
                     /locus_tag="VVR39_001733"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9016..9330
                     /locus_tag="VVR39_001734"
     CDS             9016..9330
                     /locus_tag="VVR39_001734"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU6031160.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(9431..11983)
                     /locus_tag="VVR39_001735"
     CDS             complement(9431..11983)
                     /locus_tag="VVR39_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU6031161.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKLNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12045..13667)
                     /locus_tag="VVR39_001736"
     CDS             complement(12045..13667)
                     /locus_tag="VVR39_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6031162.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
BASE COUNT         4421 a         2203 c         2490 g         4557 t
ORIGIN      
        1 tctgtggaaa acagccttta aacaagtcat atcaagtttt ttagcttgtt taaaaaatgt
       61 ggataaaaaa gataaaaaac taaaagttat ccacaaatta tttgattttc tttttgattg
      121 attcaatttc taaacgtaaa ttatcgtctt gatcaatcaa agattttatt ttggcatggg
      181 catgaatgac tgtggtatga tcttttcccc caaattcctt cccaattttt ggaagactat
      241 tatctgttag ttctctagat aaatacatgg ctacttgacg ggccaaaaca atattttgaa
      301 ggcgtctact tcccttcatt tctttgatac taacaccata aaagttacca acttcagttt
      361 ggattttatc aattgggatg acgagcattt ggctaacatc ttgtttgcgg gctctaatgg
      421 cttctgcagc aatatcaata gtgatatcct tgattttttt tactctggca attaaagtga
      481 tgtcgttgat ggctccctca agatctcgaa catttgaatc aaattgccca gctaggtatt
      541 ctagagtatc actttggaaa ttgtagccta aatgttccgt tttactttgt aaaatggcaa
      601 tacgtgtttc aaagtcaggg ggtgtgatag tttgtgtcaa tccccaacta aaacgcgtga
      661 caagcctctc ctcgagccct tctagatgtt ttggactacg atcactcgtt aggacaatct
      721 gtttttgctt gtcatgaagg gcgttaaagg tattgaaaaa ttcttcctga gttgcgactt
      781 tttttccgct gagtgactgg atatcatcga ttaacaaaag atcaagacta cgataggtct
      841 ttttaaactt ttccatttcc ccaagtctta ggtgatcaag aaagtcatta ataaagcttt
      901 cggcagggat atatttaaca cgcgcattag gaatattttt tagaatttca tttccaatag
      961 cgtttaataa gtgagtctta ccaaggcctg gtcctccata gataaaaaga gggttatagg
     1021 tcagagccaa atcttcagag acagctaaag cggctgacac agcccaaaca tttccatccc
     1081 cttgaataaa gttatcaaag gtatactttt cttttaatcc cgtatctgaa taaggaatag
     1141 atactaactt tggactatag ttataaagag ttaaatttgt agcttcttca acttgtgagc
     1201 tagtcgtatc ttgaggtttg gtgaaaatat agtggggagt tatttcagcg tcataaattt
     1261 caaaaccagc tactacaata atatctttta gttgtttttc ccagaccatt tccatttcag
     1321 agcgaggtag aaatatagtg gcaacatttt cctctacctt gatgagttca gcttgaatag
     1381 catagaaatc atacatggat cgagtcagtc tttcttgtgc aaattctaat atacgattcc
     1441 aaaattgttt ttctttcaat cctttctcct cctttactat ttaaaagttt aatactagag
     1501 atattttacc atagatagca agaattttcc acaagctgtg aaaaataatc cacaatgtta
     1561 ccaaacttta tccacaggtt ggggataaaa gaagaaatta ttgatttatt aagcttttta
     1621 tcgaaaaaca tagtggataa ccttgtgaga taaaaaaata aaagaacagc cttatttcag
     1681 gctgttgata attctactat attcttcttg atttgaaaaa gaaataatga tttttccact
     1741 gtctttttta gatagtttaa tttctacatc taatccgagt agttttctta actgtttttc
     1801 ttcattttgt atgaaatgat tagttttttg ctgtttcttt tgttttttct ctgtcagaag
     1861 agcttctaac ttccttacag aaatatcttc ttctataatc cgttgaaaga aatagtcttg
     1921 ttgttcctta tttaacccaa ctagggaacg cgcatgggct tgtgatagtt tgccattttc
     1981 tacttctgag agaatctgtt ctggcaagga aagtaaacga atggagttgc tgatatatgg
     2041 acgagacttg cccatcttat ctgcaatttc agtatgggtg aatcctttct ctacgagaga
     2101 ttcataggcg cgtgcttctt ctatcgggtt taaattttct ctctgtaaat tttcaataat
     2161 ggactggacc atcatctctt ggtctgaaat ctgtttaaca acagctggga tagaccgtag
     2221 accagctaaa agtgaagccc gatagcgtct ctctcctgca aggatttcat aaccaataac
     2281 aggagattga cgaacaataa tcggttgaat gaccccattt tctttgatag actgtgctag
     2341 ttcatctagt ttttctctat caaattcttt tcggggttga tagggatttt tttgtatatc
     2401 tgtgatagaa atcatttcaa atttttccat gattctacac taacacatct tttctcttat
     2461 gtaaagcttt ctttacatag atgtcaatca agattctaaa tcacctgaac tcttgttaag
     2521 tttgatagag gtagtttctt ctttcccgtt acgatagtag gttatcttaa tggtgtctcc
     2581 gatagaatgg ttgtaaagag cactttgtaa gtctgttgat gaagcaatct ctttgtcatc
     2641 tacttttgta attacatcgt atttttcaag gtgaccattg gcaggcatat tactttgtac
     2701 cgaacgaaca actacaccag atgtaacatt acttggaata ttgagtcttc tgatgtcgct
     2761 tgtactcaca ttagataaat taaccatctg gattcccaaa gctggacgcg tcacttttcc
     2821 gtttttttct aactgttcaa taatattgat agcatcattt gcaggaattg cgaaaccaag
     2881 accttctaca gatgttcctc catttgtagc aattttactt gaggtaattc cgataacctg
     2941 cccttgaata ttgatcagtg ggccgccaga gttacctggg ttaatagcag tatcagtttg
     3001 gatggctttt gtagaaatag cttgtccatc ttccgatttt aaggatacat ttctattgag
     3061 actggatacg ataccttgag tgacagtatt tgcatattca gaacctaacg ggctaccgat
     3121 ggcaatagca gtttctccta cagttaactt actagaatca ccaaactcag ctactgttgt
     3181 cactttttct gaagagattt ttacgacagc aatatcagag aaagtgtcag ctccgacaat
     3241 ttctccaggt actttagtcc catctgacaa tcgaatatct actttgctgg cgccatttat
     3301 aacgtgattg ttggtgacga tgtaagcttc tttatcattc tttttataaa taactccaga
     3361 tccttcacta gagattcgct gagaatctgt gtcagtatca tcattgccaa atacgctatt
     3421 ttgtctgttt gccgaataag taataacaga aacaacagca tcttttactt tgttaacagc
     3481 ctgtgttgtt gaattttcgt tcttataggc agtttgtgta atagtactat tgttgttaga
     3541 gttgtttaca ctactttttt gagttagttg agttattgaa aaactaccca aggctccact
     3601 aaaaaagcta atgacgataa cgactaataa ttgaaaccat tttttgtaaa atgtttttag
     3661 atgtttcata tttgcctcca tatgtttgaa ttactgaaag tataaactga ctagcttaat
     3721 tataacttaa acacaaaagt tttacacaaa ctgtggataa ctcttttgaa actgtgattt
     3781 tcttaattga aatctatttt ttattttgtg aataagatgt gaaaaaatag agaatatgtt
     3841 agaatagagt catgaaaatt aaagttgtaa cagttgggaa actgaaagaa aagtatttaa
     3901 aagatggtat cgcagagtat tcaaaacgaa tttctagatt tgctaagttt gaaatgattg
     3961 agttatcaga tgaaaaaaca ccagataagg ccagtgaatc agaaaatcaa aagattttag
     4021 aaatagaagg tcagagaatt ttatcaaaaa ttgctgaccg tgatttcgtt attgtgttag
     4081 ccattgaagg gaaaactttc ttctcagaag aatttagtaa gcagttagaa gaaacttcta
     4141 taaaaggatt ttctactctt acttttatta ttgggggaag tttaggattg tcatcatctg
     4201 taaaaaatag agccaatctt tctgtcagtt ttggtcgcct aaccttgcct catcagttaa
     4261 tgagactagt tcttgttgaa caaatctatc gcgcttttac gattcagcag ggattcccct
     4321 accataaata gaaaattgac ttttaattga atttttggta gaataattgt gttaggtctc
     4381 atagctcagc tggatagagc attcgccttc taagcgaacg gtcgcaggtt cgaatcctgc
     4441 tgggatcaat ataatagcaa agctgggaat tttcccggct tttttcttaa aaaagtacac
     4501 tttgggagaa aaaaatgaca gttgagagaa ttttatctaa aacgaaattc cattttgtat
     4561 aatggttttt gtaagttagc ttacaagaaa aaaacatttt aggagatttt attatgaaaa
     4621 acacagttaa attggaacag tttgtagctt tgaaggaaaa agacttacaa aagattaaag
     4681 gtggggagat gaggctgtca aaattcttcc gtgattttat tttacaaaga aaaaagtaat
     4741 gaaataaggg gaaagagtaa tggatttatt tggatttggg acagttattg ttcatttttt
     4801 aattattagt cacagctacc atttaatttg taaaggtcaa ataaatagaa aagaattatt
     4861 cgtttttggt gcttatacat tactaacaga aatagtattt gattttccct tatatattct
     4921 atatttagat gggttaggga ttgcaacatt tttatttcct ttgggcctat attcctattt
     4981 tcgatggata aaacagtatg agagggatag aggactattc ctaagtttac tactatctct
     5041 tttatatgag agcactcata actttctgtc cgtaactttc tcctctataa caggagataa
     5101 ttttgtttta caatatcatt tcccattctt tttcgttgtg acggtgttga cctattttgt
     5161 tacattaaaa atcatttatt atttccattt ggaactagcc tattttgaca aggactacct
     5221 ttatcctttc ttgaaaaaag tattttttgc tttactattg ctacatattg tatctttcgt
     5281 ttcagatatg gtaagtacga ttaaacattt gaatagtttt ggaagtattt tgtcatctat
     5341 tgtctttatc tctctccttt tgaccttctt tgcaatgaat tctcataaag ttcaaatgga
     5401 gaaagagatt gctttgaagc agaagaaatt tgaacagaaa catttacaga attacacaga
     5461 tgaaattgtc ggtctgtata atgaaatccg tggttttcga catgattatg ctgggatgct
     5521 tgtcagtatg cagatggcaa ttgacagtgg taatttacag gaaattgaca gagtttacaa
     5581 tgaagttttg gtcaaagcaa atcataaact gcgttcagat aagtacactt actttgattt
     5641 gaacaacata gaagattcag ctttacgaag tttggttgct cagtcaattg tctatgctcg
     5701 aaataatggt gtagagttta cactggaagt aaaagatacg attaccaagc ttccaattga
     5761 actattggat ttggttcgta tcatgagcgt tttattgaat aatgctgtcg aaggatcggc
     5821 tgatagctat aaaaagcaga tggaagtagc agttattaag atggaaactg aaacagttat
     5881 tgtgattcag aattcatgta aaatgacgat gactccttca ggagatctat ttgccttagg
     5941 attctccact aagggaagaa atcgcggagt ctgattaaat aatgtgaaag aactactaga
     6001 taagtacaac aatattattt tagaaacaga gatggaaggc agtacattta gacaaatcat
     6061 tagatttaag agggaatttg aatgaaagtt ttaattttag aagatgttat tgaacatcaa
     6121 gtgagactag agagaatatt ggatgaaatt tcgaaagaat cgaatattcc aatatcatac
     6181 aagacaacgg gaaaagtccg tgaatttgaa gaatacattg aaaatgatga agtaaatcaa
     6241 ctttatttcc tagatatcga tattcatgga attgagaaaa agggatttga agtggctcag
     6301 ctcattcgtc attacaatcc ttacgctatt atcgtcttta tcactagtcg atcagagttt
     6361 gcgactctaa cctataaata ccaggtatca gccctagatt ttgttgataa ggatatcaat
     6421 gatgagatgt ttaagaagag aattgagcaa aatatcttct acacgaagag tatgttactt
     6481 gaaaatgaag atgttgtaga ttatttcgac tacaattaca agggaaatga tttaaaaatt
     6541 ccttaccatg atattttgta tattgaaaca acaggggtat ctcataaatt gcgcattatt
     6601 ggtaagaatt ttgcaaaaga gttttatggt accatgacag atattcagga aaaggacaaa
     6661 catactcagc gattttattc tcctcacaag tcatttttgg taaatatagg caatatcaga
     6721 gaaattgatc gaaaaaactt agaaattgtt ttctatgaag accatcgttg tcctatttca
     6781 agattaaaaa ttagaaaatt aaaagatatt ttagagaaaa aatctcaaaa gtgattgaca
     6841 attagcaaga aattgatata atggttatat ctgctacaga tagaaggtcc gttggtcaag
     6901 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactattt
     6961 tatccgccat agctcagttg gtagtagcgc atgactgtta atcatgatgt cgtaggttcg
     7021 agtcctactg gcggagtata gataaaaggg aacacagctg tgttcctctt tttgtatcaa
     7081 tttgtatcac caagcatttt cataaggaag tctgttattt cttgagaact ttcttttttt
     7141 ccatgtgcaa tccaagtttg gcagacacca aaaagtgcat gagttagata gatgctacta
     7201 tattctaatt cggtggtatt tagattcagt tgcataaatc gcttttgtaa atctgtacta
     7261 agcatgatat gaagtttatt tcgtaagaaa ttttggattt ctttagtccc attttcagaa
     7321 agaagggcag ccagaagtgg ttctgactct agatattcaa aaacttctaa aatagcgtct
     7381 cttttgtgat gagcatgttt ttgaaaaata tattcaaatg tatggaatag cttgctttga
     7441 tagtgctcaa tcatatcata cttatcctta tagtgagtat agaagctgga acgactaatt
     7501 ccggcttttt ctactaattt gacagtagaa attttatcaa atggctgttc catcagtaat
     7561 tgtaccatag cattttcaat agttcgcttt gtttttaagc gtttgttact ttcttgcata
     7621 tttcctcctt gtaaacaaat tagactatat gtctaaaaat agatttttta tcttgtaatt
     7681 tagatttttt aatgtataat ctattatatc aaaattttag acaatatgtt taaaaaagga
     7741 gaaactaagt ttaaagaatg gaaagcaatt taaaaaaaac caacctttat tattgtcatg
     7801 atcgggattt ctcttattcc agatctgtac aatatcatat ttttgtcatc aatgtgggat
     7861 ccatatgggc aattgtctga cttacctgtg gcagttgtaa ataatgataa agaggcttcc
     7921 tataatggta atactatggc aatagaaaaa gacatggtgt ccaatttaaa agaaaataaa
     7981 accttggatt ttcattttgt agatgaagag gaaggaaaga agggattgga agatggcgat
     8041 tactatatgg tagtgacttt accaagtgat ttatctgaaa aaacaactac attatccaat
     8101 attcaatcga cagcagctta tcaatcattg acaagtgagc aacaaactga gataagtgat
     8161 tctgtatctc aaaattcaac tgatagtatt caatcggctc agtcaattgt agctttagta
     8221 caagatttac agggaagttt agaaaactta caaaatcaat cttctaatct ttcgacttta
     8281 aaaaatcaat ctaatcaagt atcacctatt acttctactt ctttgatagg attgtcaagt
     8341 ggattaacag agatacaagg agatgttact agcaaattag ttcctgccag tcagtcgatt
     8401 gcatcaggtg taaacgcata tactacaggt gttgataaag tttctcaggg cgcaagtcaa
     8461 ctaagtgaaa aaaatgccac cttgacaggt agtttggata aactagtttc aggctcaaac
     8521 accttgacac aaaaatcttc tagattgaca gcaggagttg gttaattaca atcaggatct
     8581 gggcaattag cagacaaatc cagtcagtta ctttcaggtg cttctccatt agagaataga
     8641 gctaataaat tggcagatgg atctaggaaa ctagcagaag gtggaacaaa gttaacttct
     8701 ggattggaag atttacagac aggacttgct tctttaggac aaggactagg taatgctagt
     8761 gatcaactca aatcagtatc aacagaatct aaaaatgcag agattttgtc aaatccactc
     8821 aatctttcaa aaacagacaa tgatcaagtt cctgtaaatg gaatcgcaat agctccttat
     8881 atgatatcag ttgctctttt ttttgcagca atatcaacaa atatgatatt tgcgaaattg
     8941 ccttcaggac gtcatccaga gagccgttgg gcttggttga aatcttgagc tgaaataaat
     9001 ggtattatag ctgttttggc aggaattttg gtatatggag gagttcagct tattggttta
     9061 actgctaatc atgagatgag aatatttatt ctcatcatcc taacaagttt agtattcatg
     9121 tctatggtga ccactttagc aacgtggaat agccgtatag gagctttttt ctcacttatt
     9181 ttgcttttac tacagttagc atcaagtgca ggtacttatc cacttgcttt gacaaatgat
     9241 ttctttagat ctattaatcc ctggttacca atgagctatt cagtttcggg attacgacaa
     9301 acaatctcta tcaacaagtc attttcctag ctgtcatact agctctattt actggtttag
     9361 gtatgctagc ctatcaacat aagaaaatgg aagaagatta aaaaaatcga ccgattaact
     9421 ggtcgatttt ttatgcctta gatgactttc gtctgtgatt atagattcca aatagtaaga
     9481 gagaagtaaa ggaacagatt gctccagtaa taaaaccatt gggaatgaag gaaagtgtaa
     9541 tagttccttt ccccttggga atgtcaactt tcataaatcc agtttgagct tgtttaattt
     9601 ctattttctt accatcttgg taggcagacc aacctttgtc ataaggaatg gtgaagaaaa
     9661 tagatgtatc ttgttggaca tcatatgtag caaaaacctt gtttttagaa gttgatactg
     9721 tgacaggttg ttctttaatt ttttgaattg cctcggtgaa agttttggta tctaaacgat
     9781 agaaggtagg agattcaaat gatacttgtg aatttccagg gaaactaaca ttgatattga
     9841 aagttttttt ctctttagta tatcctagat taaagaagga gaagacatta tcagttgtaa
     9901 aagtcttttt ttcaccattt acaaggatgt caaccttctt ttgtttatcg ttagaaaagt
     9961 gaaggtttat gaaagagaga taaacttggc tgttttctgg aacttcaatt tgatactgga
    10021 ttgctgcatc ttcatttgaa gaacttgtga cactaatcaa atcattagta ttttctattt
    10081 tttctgtttt ttcataaggt attggagaaa aataatcaaa attgacgtta gcaagttgat
    10141 ttaaaaatga ggcctgatta tccaaggtat gttcatttaa cttgacatca ttgtaaacag
    10201 attgactagc aactgcaatc ggaagagagt attgattttc atatagggta agattatctt
    10261 tttgatagat atctttaaag ccatacttat caataggact gtctgagata ttgtactgga
    10321 taccaaataa actatcagcc aaaatactat tatttgcata tcggagattg agattagtcc
    10381 cagaggattt aaaaccaagt ttatctaaag tagagcttga tgaacgattt cgaacagatg
    10441 aaaattgaga gattccattg tagttgaatt tcatactgtc atttcctgtc tgagtttgta
    10501 gtttttcagt acgagtaaat tgatttccaa tatatgttga gaaagattcc atagctggga
    10561 tatctcgact ataagcactt cgagaagcaa atccccattc cttagcaatt ccgtccattt
    10621 gagatgaagc atttaaactc atttcaacca gtataaataa agagattaga atggcaaata
    10681 gattcacaga tataaacttt ttgataactg caaggagtaa aagagaatag acaaccaaaa
    10741 attcaagagt aagcagaata ttcaaatctg ttaaaaaaga ataatgcgat tttagataga
    10801 tggtagctaa aaatcctgct actacaagaa aaagcgaaac taaaaaattc cagactttaa
    10861 gttctttcag acgctttaag acttctgctg ctgtgtaaat taacaaggta gagaaaatcc
    10921 aagcatagcg atgtaaaaac atgtttggag tatgcatgcc ttgccaaaat aagtcaagag
    10981 cttctatgta aaagcttgca attagaaatg caaagaatat tacatatatg agtttcacgt
    11041 gaaacttaat agatttcagc gtaaaaaata aaatggtcaa aataaaggga aatagtccaa
    11101 caaaaatcat tgggatggcc ccatactttg ttgtgtcaaa ggaaccaatg aattgcttag
    11161 caaagagatc aagataccag ctactttcag tttgaaactt tgtaacttca gtcaattttt
    11221 ccccatgtgt ctgtaaatca aatagagtgg gaagagtcat aatcaaacta gccataccag
    11281 ctaaaaagga gataactatg aaatcaagaa cagatgattt tcgagtctta aagtcccacg
    11341 aaatttgaca gagataccag aaaataagaa acaatactgt catatatcca aaataataat
    11401 tttgaataaa taagattgac agacttgtaa agtacaatag gagtttcttt tcagttatca
    11461 gtagatgtaa accagttata attaaaggaa tcaagataaa aacatctagc caggttttta
    11521 tctctaattg actgacagtg aaactcatca gagcatagga agtagataag gctagtttta
    11581 aagtctgagg gatagattga aacaatttat tcaaactaaa aaaggttgac agaccaatca
    11641 atccaaattt taagagagtg gtcagataga cagcatctgg catattcgtt agatcaaaaa
    11701 agtaaactag aggcgcgaga aaactaccca agtaataact agatagggca tagaagttta
    11761 gccctagacc acttgtaaag gtgtaaaaca gactactatt tccatgtagg atatttcgta
    11821 aggctacatc aaaaataacg tattgatgaa agccatctcc taatagagga gagttgtcgc
    11881 tattccagta gataccttga gatagatata ctccagacat aatcactaca ggaatgatga
    11941 aagaaataaa ataggttcga tatgttttta aaaatgattt catgttacct cgtagaatga
    12001 tagaaaactc agttggttaa cccaactgag ttttgaagtt ttatttagtc tttccaaagt
    12061 tctttaactt ttgcttgtac ttctgcattt tctaggaatt catcgtaggt ttcatcgata
    12121 cggtcaatga cgccattttt agataagaca atgatatggt tagccaaagt ttgaataaat
    12181 tcgtggtcat ggctagcaaa gatgattgat tctttaaagt ttttcaatcc atcattcaag
    12241 cttgagatag attccaagtc caagtgattt gttggatcat caagtacaag gacatttgat
    12301 tttaagagca tgagttttga aagcatgaca cgaacttttt ctccccctga caagacattt
    12361 acaggtttgt taacttcatc tccagagaag agcatacggc cgaggaagcc acgtaggaaa
    12421 gtattgtcat cttcttcttt acttgcgaat tgacgcaacc agtcaagaat tgattctcct
    12481 cctgcaaaat cagctgagtt atcttttggt aggtaagatt gactagttgt aactccccac
    12541 ttgacagttc cttcatagtc aatatctccc atgattgcac gaattaatgc agtcgtttga
    12601 atatcatttt gtccaataag tgctgtctta tcatctggac gcaagatgaa actaatatta
    12661 tccaagatag tttcaccatc aatctttaca gttagatttt ctactgtcaa gagatcatta
    12721 ccaatctcac gttccgcttt aaagttgata aatggatatt tacgactaga tggcacaatc
    12781 tcttctagct caatcttatc aagcattttc ttacgtgatg ttgcctgcct tgacttagaa
    12841 gcattggcag agaaacgagc aacaaattct tgcaattgtt taattttttc ttctgcttta
    12901 gcattacggt ctgctagcaa tttagcagca agctcagaag attccttcca gaagtcgtag
    12961 tttccgacat agagtttgat ttttccaaag tcaaggtcgg ccatgtgagt acaaactttg
    13021 tttaagaagt gacggtcgtg ggatactacg ataactgtgt tatcaaagtc aatcaagaag
    13081 tcttctaacc aagtaatcga ttggatatcc aaaccgttag taggctcgtc caagagaaga
    13141 acatctggtt taccaaaaag tgctttggcg aggagaacct ttactttttc accgttggcc
    13201 aattcgctca tgttttggta gtgtaattct tctggaatgt ttaggttttg aagtagttga
    13261 gaggcttcac tctctgcttc ccaacctcca agttcggcaa attctccttc gagttcggca
    13321 gcacgaaccc cgtcctcgtc tgagaaatct tccttcatgt agatagcatc tttctctttc
    13381 atgatgctat aaagtttttc atttcccatg ataacgacat caatggcacg ttcatcttcg
    13441 tagtcaaagt gattttgacg aagaacagag agacgttcat ctggaccaag agagatgtga
    13501 ccagtagtag gttcgatatc tccagctaaa atttttaaaa aggttgattt tccggcacca
    13561 ttagcaccga ttaatccgta agtatttcct tctgtaaatt tgatattgac atcatcaaaa
    13621 agtttgcgat cactaaaacg tagtgaaaca tcagatactg taagcaatat t
//
LOCUS       DAVHSL010000053        13659 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000053 DAVHSL010000000
VERSION     DAVHSL010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.055"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            152..1042
                     /locus_tag="VVR39_001737"
     CDS             152..1042
                     /locus_tag="VVR39_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031163.1"
                     /translation="MDNTKVIEWLNYCDQNDIKPWLWDFKNCYSSELTADNISNFLKY
                     KNGELVNPSTFCITKQVGSNADCDKEALPLYNVLGWQHSERDIIRGETLNSYITTFTQ
                     AITNDPNYKEICKKIGVNLNEYLNKQYPILHHNKNYQNFKMIQKNLKEFEAFAKLTHT
                     IGNFTVLPHWMNTGRYNFSKDYWDITMLSLQEWLTNLSPQAWKNFIDTYYLQPYVDNN
                     YQTEVFWETHNYEYIYPKKTEDFSIFLKRVNERIEERGKFIIKQICDKLNKKDFHFYK
                     EIENMDKIKYSNEFEQERKQ"
     gene            1039..1509
                     /locus_tag="VVR39_001738"
     CDS             1039..1509
                     /locus_tag="VVR39_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031164.1"
                     /translation="MTRVYKSVRLAYEAKVWIDELIQEKERKIQELNKEDFLDKLEKT
                     LLKNHYDELNGLSFNIILKASIGSVIEESYRNTKHYPIDKWQKLRQQMERDVKNVNPN
                     LETTVTPRIYLDEDVLAGLDDFRYVLMKEDCATRLPRLSYIIKLVVYSYWKEQH"
     gene            1596..2264
                     /locus_tag="VVR39_001739"
                     /pseudo
     CDS             1596..2264
                     /locus_tag="VVR39_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            2227..3405
                     /locus_tag="VVR39_001740"
                     /pseudo
     CDS             2227..3405
                     /locus_tag="VVR39_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3668..4060)
                     /gene="rpsI"
                     /locus_tag="VVR39_001741"
     CDS             complement(3668..4060)
                     /gene="rpsI"
                     /locus_tag="VVR39_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU6031165.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(4079..4525)
                     /gene="rplM"
                     /locus_tag="VVR39_001742"
     CDS             complement(4079..4525)
                     /gene="rplM"
                     /locus_tag="VVR39_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU6031166.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            4881..5198
                     /locus_tag="VVR39_001743"
     CDS             4881..5198
                     /locus_tag="VVR39_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU6031167.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     FEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(5243..6055)
                     /gene="folK"
                     /locus_tag="VVR39_001744"
     CDS             complement(5243..6055)
                     /gene="folK"
                     /locus_tag="VVR39_001744"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU6031168.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFTNQVVEVETWLPAQVLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(6098..6652)
                     /gene="folE"
                     /locus_tag="VVR39_001745"
     CDS             complement(6098..6652)
                     /gene="folE"
                     /locus_tag="VVR39_001745"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU6031169.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(6633..7955)
                     /locus_tag="VVR39_001746"
     CDS             complement(6633..7955)
                     /locus_tag="VVR39_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6031170.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(7957..8931)
                     /gene="folP"
                     /locus_tag="VVR39_001747"
     CDS             complement(7957..8931)
                     /gene="folP"
                     /locus_tag="VVR39_001747"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU6031171.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMPHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQCVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(9026..9733)
                     /locus_tag="VVR39_001748"
     CDS             complement(9026..9733)
                     /locus_tag="VVR39_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6031172.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIIPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(9787..11205)
                     /locus_tag="VVR39_001749"
     CDS             complement(9787..11205)
                     /locus_tag="VVR39_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU6031173.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            11395..12207
                     /locus_tag="VVR39_001750"
     CDS             11395..12207
                     /locus_tag="VVR39_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6031174.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            12549..13568
                     /gene="adhP"
                     /locus_tag="VVR39_001751"
     CDS             12549..13568
                     /gene="adhP"
                     /locus_tag="VVR39_001751"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU6031175.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         4350 a         2863 c         2527 g         3919 t
ORIGIN      
        1 aatttaacgc tatgaaattt aaatatagcc ataacttaca atccacaaaa aaatatttga
       61 aaaaattttt ttctaaatct cttgcatttt ctgaaaaaat agttataata aaagtatagt
      121 tgttttacaa caaaatagaa taggtagaat tatggataac acaaaagtta ttgaatggtt
      181 aaattactgt gaccaaaacg atatcaaacc atggttatgg gattttaaaa attgttactc
      241 tagcgagtta accgcagata atatttcaaa ttttctaaaa tataaaaatg gagaactcgt
      301 aaatccttcc acattttgta tcacaaaaca ggttggtagt aacgctgact gcgataaaga
      361 ggcactccca ctttataatg ttttaggttg gcaacattcc gagagagata taataagagg
      421 tgagacctta aattcttata taactacatt tactcaagct attaccaatg acccgaatta
      481 taaagaaatt tgtaaaaaga ttggagtaaa cttaaatgaa tatctaaaca agcagtatcc
      541 aatcttacac cataataaaa actatcaaaa tttcaagatg attcaaaaaa acctaaaaga
      601 atttgaagca ttcgcaaaat taacacatac aatcggaaac tttactgtat tgcctcattg
      661 gatgaatact ggacgataca atttctcaaa agattactgg gatattacaa tgctttctct
      721 tcaagaatgg cttactaatt tatctcctca agcatggaaa aattttattg atacatacta
      781 tcttcaaccc tatgttgata ataactatca aacagaggta ttttgggaaa ctcataacta
      841 cgaatacatt tatcccaaga aaaccgaaga tttctccatc ttcctaaaaa gagtcaatga
      901 acggattgag gagcgcggga aattcatcat taaacaaata tgcgataaac taaataaaaa
      961 agatttccat ttctataagg aaattgaaaa tatggataaa attaaatact caaatgaatt
     1021 tgaacaagag aggaaacaat gactagagta tataaaagcg tccgccttgc gtacgaggca
     1081 aaggtatgga tagatgaatt gattcaagaa aaagaacgta aaattcaaga acttaataaa
     1141 gaggattttc tagataaact tgaaaaaaca cttcttaaaa atcactatga tgaattgaat
     1201 ggtctttcat ttaatatcat tctaaaagcc tcaataggga gtgtcataga agaatcctat
     1261 cgaaatacta aacactatcc aattgacaaa tggcaaaagc tacgtcagca gatggaaagg
     1321 gacgtaaaaa atgttaatcc taacttagaa accacagtta ctccccgtat ttatctagac
     1381 gaggatgtgc ttgctgggct tgatgatttt cgctatgttt tgatgaaaga ggactgtgct
     1441 actagactac ctcgtcttag ctacattatc aaacttgttg tatattccta ctggaaagaa
     1501 caacactaat ctaatcagtt ctactgttta gattttcatt tctttaaaat gtatatttgt
     1561 tgtactacta ataaatctag aaaaataggt aatctatgtt taaattaaag aaagtcgctg
     1621 acttaaaaag aaattatatc atttcaacta acaaattaaa ggtaactcat tggtcaatat
     1681 taagcctctc tatctgcatt atgcttacta ttattgcaaa tattagagcc cctgacctta
     1741 ttaaaatccc tttacttatt ctagtaggat ttgtcatata caaatttcat cgtcaattaa
     1801 aatattttag atataattta gattattacc taattatcag agaaagctta ttgtatgtat
     1861 tacatacaaa ccgcctttat acaacacata aagatagctc aggatatgaa aaaatctcta
     1921 ggagcgcaat cttacaatac gagttagaca aacaaaaggg gcatatcttt atcaaagctc
     1981 tgattactgg tgatgaattt agtaaaaggg tacaatcact tgatgatgtt cttgctggag
     2041 tactcgaact ggaactagaa tacaaaatta ttcgtcctag ttttatggaa taccatttct
     2101 attacaagaa acctgacagg ttagttcttc aatctcacaa ccagaagcaa gagatagata
     2161 accttaatat agatttagga tacggtgtga attataatcc tatcaagtgt cctcatattc
     2221 tagttgctgg aggtacagga agcgggaaat cagtatttat atctttaagg aaatcacttt
     2281 gttaaacgct ataaaacaag aaaggaggct aaagaagctg aattagaaat tctaacaaag
     2341 atacatcaac ttgaaaatgg agaggatatc ccactcctta aaactagtga tattcttttc
     2401 tctgagttct ttaataatat ttggtgggat tcatacaaag ctggtcaaac aacttcaaca
     2461 actaaacccc caacacaagt tactattgat aatactgaaa tagttttcag gaagcacatc
     2521 ttaccaatgt tcggtaatta ttcaatcaat tttctgaatc agaataagca aatcgtacta
     2581 aacttaatga ctgctaaagc tgaagaatat gctaatttca aggttattcg aagctatgta
     2641 aactcaattt tcgattgggc tgaagaatta gaatacattg aatcaaatag attatcaaaa
     2701 agcataaaac gtattaaagc aagtaaaaaa ataaagctag aagaagctaa ggatgaggaa
     2761 gatttgtatc tatctagtga agaattacaa gattggtttg atgcttttag agaagatttg
     2821 gagaacgaca aattatcact aaaagattat gtcctattct ttacaacctt tattttgagc
     2881 gatagaaaat cagaatccta tgctctacat tggaaaaaca tagacttggc aaacgctcaa
     2941 attggcttaa ggcatgcact tgacaaatat aagaatgtaa agtcaacaaa aggaaataag
     3001 aaaacgattt tttcaattcc tagttacctt gtatcacttc tttcagaatg gaaaaaacag
     3061 cagaaatatg agttagcgaa atttggtata atgcaaacat ccgatcaact agtctttacc
     3121 tatatagata cgaaaggtaa tgtaaatagc cctctacacg ttgattatct caataacaaa
     3181 atgaactctg taaaaagacg acacccaaag ttaaaacacg ctacacctca taaattacga
     3241 catacaggag cgacacttgc taaaaaggca ggaatgagct tagaagccat ttctgaagta
     3301 ttaactcata gtgatacaat tacaactaaa acttatgtta atgcttcaaa catagttcca
     3361 ttatctgctg gacaagttgc ctaccaacat cttaaaaaca agtagggtaa ttttagggca
     3421 aattttaggg aaaacttttt tagaaagtat agaaaaaagc acccataggg caaacctttg
     3481 agtgctttga aacattgata taatcgtatt gattaacgtt ttgaggtaac tgaccttgtc
     3541 aggttgcagc cacatttgta agcgactaaa gtcgcaacaa ctgtgtcaat tgcaccaatt
     3601 tagtaagaaa gtataaaaaa agaacacccc gaaaggtgct ctgtataagt atagtaattc
     3661 tttcgaatta acgtttacta aattgtgatg ctttacgagc tttcttaaga cctggtttct
     3721 tacgttcaac tttacgtgag tcacgtgtaa gaagtcctgc gcgtttcaat gaatcgcgga
     3781 agtctgggtc tacttgaaga agggcacgag cgataccatg acggatagct cctgattgac
     3841 cagcgtatcc accacctaca acgttaacga aaacgtcgta tgaacctaca gttgaagtaa
     3901 ctgcgaatgg ttggttgatg acaagacgaa ggtcagcgtg tgggatgtac tcttcaacat
     3961 cttttttgtt aacagtgatt ttaccagttc ctggaacaag gcgaacgcgt gcaacagcgt
     4021 ttttacgacg tccagtacct gcatattgtg cttgtgacat actttattgt tcctttcctt
     4081 agataagtcc tgaaatgtca agaacttctg gttgttgtgc agcgtgagtg tgctcagctc
     4141 caacaaatac tttcaacttc ataccttgag cgcgtccaag tgtattgtgt ggaagcatac
     4201 ctttaactga tttctcaatc aaacgtactg catttttaga acgaagttca cctgcagaga
     4261 tttgtttcaa tccacctggg tggtttgagt gagtgtagta gattttatca gttgcttttt
     4321 taccagtcaa tttaactttt tcagcattga taacaatcac gaagtcacct gtatcagtgt
     4381 gtggtgtaaa tgttggtttg ttttttccgc gaagtacgct agcaactact gcagaaagac
     4441 gtccaagtgg tacatcagtt gcgtcaacta cgtaccattt acgttcaact tggcctggtt
     4501 tagccataaa tgttgttttg ttcatgattt ctcctatata tagttcgatt tttgtttacg
     4561 gtgatgggtg ttccttccca tcgaaaagta tttggaaggt tccggggcct ttcaaatggg
     4621 gtaaacaata ccgcctacta tcataccaaa tttcacccct aaaagtcaat agatatgaaa
     4681 aatatttttc ggtaacttct caaagtaact gaaagttata taatcaagtt aatttgggaa
     4741 tttacctatt aacttcggta gatttttggg atttttttcc ttctttttcc ctgtagttaa
     4801 aatccttttc aaaaaatcac cttttcttga tttttaatcc tatttgctgt atgataaggg
     4861 aaaagaaagg ggacagagat atggctttta ccaataccca catgcggtct gctagttttg
     4921 gcattgttac cagcttgccc gatgacatca ttgactcttt ttggtatatc atcgatcatt
     4981 tcttaaaaaa tgtctttgaa ttggaagaag aattcgagtt tcaattgctt aataaccaag
     5041 gaaagattac cttccacttt tcaagtcaac acctccctac agccattgat tttgacttta
     5101 accatccttt cgaccctcgt tatcccccaa gagtactggt tttagacatg gacggtagag
     5161 aaactatcct cctcccagaa gaaaatgacc tattttaaaa actctagcct tcagttgcaa
     5221 gtaactgaaa actagagttt ttctattttt tcaaagcatc atacaagttg cggatcggtt
     5281 gttttaatat cggatggata aaatgaggcg caatttcctg taaggactca aggacaaaaa
     5341 ggcgttccgc tatgtaagga tgaggcaata tgaggtcgtc tgtataaagg atctggtcct
     5401 ccacaaagag caagtccaaa tcaatcaaac gagggcccca atgcacttct ctcacccgtc
     5461 ccagctctga ctcaatggct aacaaggttt ctaatagcac ttgggcaggc aaccatgttt
     5521 ctacttcaac cacttgattg gtaaagctat cctgctcaac accaccccaa ggctccgtcg
     5581 ctaagacact ggactctttg agaatatgga tgccacgagc tcgcagtttg tcaatggctt
     5641 gcttcaagtt tgcttgttta tctcccatat tgcttcctag ggcgataaag gctcgttgct
     5701 tgcggcgatg aatggttacc gagcaagtat ctagtgacaa atgcaccggt gcccaaggtt
     5761 ttttcagttc caacttcatt tcttggacaa gaggataaga ctcaaaggta cgttccacca
     5821 gtttataggc taccgtttca atcaaatctt cactcgtttc ctgaaaccaa gtcgtccact
     5881 gctgacacaa ttctccgtaa tggacagagg ctgttaaatc caagtctgta gctgccttgg
     5941 tcatatcata ggataggatg gctgaaacga caaatttctg ccccaattct ttctcactag
     6001 gaaaaagacc atgataggca aacatttcca aatccttaat ctgcagttga tccataatga
     6061 ttcctttcta gaaaaatccg cttgaagcgg attcttttta tagccccatt aaacgataag
     6121 cttggtcgcg gaggtcctta tctgtttcaa atagaccacg agctactgtc gtcaaggttg
     6181 cagtgcctgg ttttctaaca ccacgcatac tcatacacat atgttccgcc tcaatgacaa
     6241 caaaggctcc tttagcacct agatagtcca tcaaggcatc ggccacttca atattcaaac
     6301 gttcttgaat ttgtggtttt ttcgaataaa cttcaaccgt acgggctagc ttagacaagc
     6361 ctgccacacg accatctgga atgtaggcaa tgtgcgctct accataaaat ggcaagaagt
     6421 ggtgttcaca catggtatgg aaaaagatat ccttttctac caccatatta tcgtcaataa
     6481 tttcaaagga ttttgacaaa tgttcctctg ctgtttgacc aagacctgaa aaaatctctt
     6541 gatacatacg ggccacacga gcaggtgttt cctgcaagcc ctcgcgatta gcgtcctctc
     6601 ctacagcctc gataatcatt ttcacagctg cttcaatctt ttgtgtatcc attctcgttc
     6661 ttcctctcca tcagataggc cctcacttgg ctcaagaaat acaaggaacc tgtgacaatc
     6721 ctaactgttt gtttctcttc ttttttatct gtcacattct gctctagaaa atcatgccaa
     6781 tcttggtagc tgagatttct agacttagct gcctctttca gcacgctttc atccgtcgcc
     6841 cgactatccg caaaatgtgt tagagtaagc tcggtatctg gcatggctcc cagcaagtcc
     6901 aacatatcct ccaaggcctt ggttttgata caagtgaaga ggatttcctt atgataatcc
     6961 gcaaaacgtt cttgcaaggt taccaacaag gccttgatag catggggatt gtgggctcca
     7021 tccaaaatca tcaagggatc tcttgacacg atttccaaac gccctggcca acttgtttct
     7081 tccaaggctt gaccaagaaa gtcattgctt gctagctctc gaccatcttc ttgacaaaaa
     7141 gtatcaagta aagctatggc catcccagca ttctctattt ggtacaaacc aagcaggcta
     7201 gtctggaagc gaccttgtct gacagcactt gtatagtcaa agacttcccc tgtcaccaca
     7261 ctttcttgat gacgaacctg ataatctgtc ccgtaggcaa gtctcggcgc atctttccct
     7321 tccgcaatgc ggtcaatcac agccaaggct tctggagcaa tacgccctgt taccaagggc
     7381 atcccttgtt tgataatacc tgccttctgc tctgctatgg cctccaaggt gtcaccaagt
     7441 agggccacat gatccaagcc aatagttgta attcctgtca aaatgggctg acagacattg
     7501 gtactatcca aaagtccacc catgccaact tccatgatgg ccacatctac ttgctctgag
     7561 gcaaagtagt cataggccag ggctgtgata atctcaaact cggttgtgcc ctgtaaattg
     7621 gcgaccgctt ctccctccag caaagactga tagtctgcca tgagagcttc tagcctcgct
     7681 tctgagatcg attccccatt gatgctaatc tggtctgtgt aatgaatgag atagggcgag
     7741 ctaaacacgc caactctcag ccctagcttt tctagcatct ttttcaaaaa agcaatagtc
     7801 gagcccttgc cgttagtccc tccgatatgg aggaccttga gtttgagatg gggattgcca
     7861 cgcaaagcta acagttccac cattcgttcc aagccaaaat gcggttgatc cgtccggtag
     7921 ttagcaatcc actgattgtt ttcaatttct ttcatcttat ttatattgtt ttaaatctaa
     7981 attttccgct tcatcagcca gacgaatggc agaggcaatt tcaactgcca tcctgtgact
     8041 agctacgtca tgcacgcgca ccacttctac acactgtctc gcagcgatac tagttacatg
     8101 agccgaagcc gtgtcccgat tgcggaaacc aagctctgtc tcaggattga cttcaaaacc
     8161 attctcctct aggatattga tgacaaatcg cttgcgcgac actccgagaa agattggata
     8221 gcccttctga tgtagtttat ccaggtcccg taaaagaagc agattttctt tcttggtcag
     8281 accaaagcca attcctggat ccaacaggat attttctggt gcaataccag cttctgccgc
     8341 tctcgctagt gctcgttcaa agaaagcctc catcaattct tcgattggca atgtttcaaa
     8401 gtcagctaac tcttcctctg taaaagcttg accaaaacca aaatgaggga agatgagcga
     8461 gctagggtgc tgaggtcgcg ccataactgg attaaacatg atgaccactt gcgctctcgc
     8521 ttcagctacc acatgaggca ttttctcatc acccataaga ccagtgatat cattgactag
     8581 atcggcacca gcagccaaag cagcctctgc tacttgactc ttccaagtat caatagagat
     8641 gaggacatca ctttccttgc gaatcgcttt gatcactgga acaacacgct ggatttcctc
     8701 ttctatctca acatagctac tgcccggccg agtcgattct ccgccgatat cgagcatact
     8761 ggctccttct gctatcaatt tacgagcctg ctggagtgcc tgctcaagag caaaaaattg
     8821 accaccgtcc gaaaaggagt ctggggttac attgataatt ccgcaaataa ctgtctttgc
     8881 atgattggct ttacttgaca tatcggtcac tccctcaagg attttcatca tattattttt
     8941 ctattttacc ataaaaagaa aaagatggac acgattgcat tcatctttcc ctagtagaaa
     9001 gaggtcggtt cctacataaa aacttttaca cagaaattcc taatgtccga ctcataatca
     9061 ccacaagagc caacaaacag aaagcaatcc cattaacaat catgtgaagc aagatcgaca
     9121 tttccaaacg ttgggtcttg taggctgtcc aagatagaac tgtcgacata cctccataaa
     9181 tcaataaaga aggtaaatta cttggttgat gcaataaagc aaacacaatc gtaccgacta
     9241 caaatcccaa gttctccttg cctcggaaaa tctttttagg aataatccca cgacacaaga
     9301 tttcctcaca aatcggagca agcaaggcta gcaagaagaa actggaaatc aacgaactat
     9361 tttgaaccat atcattaatc tgagactggt tagcagttgt cgtctcattt gacagttgca
     9421 acaagataga accaagtata tttgacccga caataactag ataactcaag cccaaacgtg
     9481 ccaaatcttt agctctaaaa aaagaaaaat taaaactagc taacttggtt ttacgagctc
     9541 ccataataaa tagagccaga accacaattg aaaggccagc aactatcagc cctgactgta
     9601 gcagggctac ttcttttaaa gtcaaaatag aggtaaccac taggggaacc tgatataaaa
     9661 ggacggcaag taaaaagacc aaaatccagc ctgcacgatt caacaattct ttccacatat
     9721 ttttctcttt catcacctat ctccttttgt attaaaaaag gggggaaatc cccctgggtc
     9781 attctattat aaggccatgc tgatgtagtt aaggataaac aaggcatcca aaatccaaat
     9841 catggcatga acatctttaa cttgaccttt gacaagctta gtcaaagtgt aagtcaagaa
     9901 accaactgca atcccttgag tgatagagta gctgaatccc ataaagatag atgtgaagaa
     9961 ggcaggaact gcttcagaca tatcatccca atggatattt ttcaagctac caagcatcat
    10021 aatcccaacg ataatcaaga ttggagctgt agccgctgtt ggtacgatcg ctagaagtgg
    10081 gctaaagaag cttgaaatcg caaaacagat agctacaacc aaggctgtca aaccagtacg
    10141 tccacctgca ccgataccag cagcagactc aacataagtc gttacgtttg aagtacctgc
    10201 aatggcaccg actgtcgttc caatcaaatc agagtaaaga gccttatcca atttggctga
    10261 ttggtgattt tcaccatttg tcgctacaat accaactttt tcacctgtac cgatcaaggt
    10321 accaattgtg tcaaaaatat ctgtcaatga gaaggcaaga atggccatca gagtttcagg
    10381 caagcgagct gtatctgaaa ccaaagctcc caaaccttct gaaccaagag ctgcaccaaa
    10441 gattgtcttc aaatcttcaa aagctgcacc aacatggtta ttagcaaaat cgatactaga
    10501 caaatcaacc aaaccaactg caatagcaag aacagttgtt gtcaagatag agagaataat
    10561 tcccccttta atccctttga tgacaaagaa gatagtaatg gcaagtcctg caagagccac
    10621 taaaacagct ggattattaa agctgaccaa tcctggaact gctgaagagt ttgctgcaat
    10681 cgttgcttga gctttgtcag ccccttctcc tacaacagta tagttgcctg gatcaatcgt
    10741 gaatttcaaa agtccagcat tcttaatccc tacataggca aggaagacac cgataccagc
    10801 tgaaatagct gagcgaagag cattgggaat cgattcaatg atcattttac gaacatttgt
    10861 caaggtaata atcaatgaaa taatcccaca gatgaagacc atagctaggg cttcttgcca
    10921 agaataacca agcccgaata caactgtaaa ggtaaagaag gcattgagtc ccatacctgg
    10981 cgcttgggca taaggtaagt tagcataaaa agccatcatc aaggtacccg ctactgcacc
    11041 aataatcgtc gctaggaaga cgccctgagc aggcattcct gtttgtgaaa gtatttgtgg
    11101 gtttacaaag agaatatagc tcattgcaaa gaaagttgtt aaaccagcga gaacctctgt
    11161 acgaacgtct gtaccgttct cttttagttt aaataatttg tccatcatca atctcctttt
    11221 aatttttacg aacaataata gaattatatc atttatcatt cactttttca atgtctttgt
    11281 ttgatttgtt taagaaatta atccaatttc attttttgtt tggaatctgc ttttctgcct
    11341 gctttctgtt ataatagaag acatcttatc tgaaaacaca ctagaaaggt ccatatgacg
    11401 aaaaaaatta ttgcagttga cctggatgga accctgctca actcagacag tcaaatttct
    11461 gactttacca aaagaaccat caaaaaagtt gctgaaaaag gccatcaggt tattattacg
    11521 acaggtcgcc cttaccgtat gtcaaaagat ttttaccgtg aactgggctt agacactcct
    11581 atgattaact tcaacggatc ccttactcat ttaccagacc aagtttggga ttttgaaaag
    11641 tgtttgactg tagacaaaaa atatctgcta gatatggttc aacgttcaga ggacattcaa
    11701 gccgatttta tcgctggaga atatcgtaaa aaattctaca ttacaaatcc caatgaagaa
    11761 attgccaatc ccaaactatt tggtgtagaa gctttccagc ctgaagatca attccagcct
    11821 gaattggtga ccaaggaccc taactgtatc ctcttgcaga ccagagccag tgacaaatat
    11881 gccttggcaa aagaaatgaa cgccttctac cagcatcaac tttctatcaa tacctgggga
    11941 ggtccgctca atatccttga atgtacccca aaaggtgtca acaaggcctt tgctttggac
    12001 tacttgctca agataatgaa tcgtgacaaa aaagatttga ttgcctttgg agatgaacac
    12061 aatgataccg aaatgctcgc ttttgctggg aagggttatg ccatgaaaaa tgccaatcca
    12121 gagctactcc cttatgcaga tgagcaaatt tcccttacca acgaccaaga tggggttgcc
    12181 aaaaccctac aagacttatt cttataacct atactgatac tcaatgagaa tcaaagagca
    12241 aactaggaag ctagccgtag gttgctcaaa gcactgcttt gaggttgtag atgaagctga
    12301 cgtggtttga agagattttc gaagagcaca aagaccagct tgcaagctgg tctttgtgct
    12361 cttttcacag tctcatcaac cagttaatcg attgttctac tttttgtctc caaaaccttg
    12421 gaaaaggctt tcttttgtga tatacttcac atataaatac aagagagctc gtcacactcg
    12481 actctgttga caaaaaatca atccagtccc gttgtccctg ttctcggtca atatcaagga
    12541 ggatagctat gaaagctgtt gttgtaaatc cagaaagcac tggtgttgct attgaagaaa
    12601 aagtactccg tccacttgaa actggggaag cacttgtaga agttgaatac tgtggtgttt
    12661 gccacaccga cctccacgtt gctcatggtg actttggtca agtcccagga cgtgttcttg
    12721 ggcacgaagg tatcggtatc gttaaagaga ttgctccaga tgtgaaaagc cttaaagtcg
    12781 gtgaccgcgt cagcgttgct tggttctttg aaggatgtgg cacttgcgaa tactgtacaa
    12841 ctggtcgcga aaccctttgc cgtacagtga aaaatgctgg ctactcagta gacggtggta
    12901 tggctgaaca atgtatcgta actgctgact atgctgtcaa agttcctgac ggacttgatc
    12961 cagcccaagc ttcttctatc acatgtgctg gagtaacaac ctataaagct atcaaagaag
    13021 caaaagttga accaggccaa tgggttgttc tttacggtgc tggtggactt ggtaacctcg
    13081 ctgttcaata cgctaaaaaa gtattcaatg ctcatgttat cgcagtcgat atcaacaatg
    13141 acaaacttgc ccttgcaaaa gaagtaggcg ctgacattgt gattaacggc ctcgaagttg
    13201 aagatgtagc tggactcatc aaagaaaaaa ctgatggagg agctcattca gctgtcgtaa
    13261 ctgctgtgtc taaagttgcc ttcaaccagg ctgttgactc cgttcgtgct ggtggtcgcg
    13321 tcgtcgctgt tggtcttcct tctgaaatga tggaactcag catcgttaaa acagtcctcg
    13381 atggaatcca agtcatcggt tctcttgtcg gaactcgtaa agacttagaa gaagccttcc
    13441 aatttggtgc agaaggtctg gtagtcccag ttgttcaaaa acgtccagta gaagatgctg
    13501 ttgccatttt cgacgaaatg gaaaaaggcc aaatccaagg acgtatggta ctcgacttca
    13561 cccactaatc taatagaaac ctattttaaa agttggaaac ttcttccaac ttttttatat
    13621 taaattttta aataagaatt caagattact cctcaaaaa
//
LOCUS       DAVHSL010000054        13480 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000054 DAVHSL010000000
VERSION     DAVHSL010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.056"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(182..1081)
                     /gene="htpX"
                     /locus_tag="VVR39_001752"
     CDS             complement(182..1081)
                     /gene="htpX"
                     /locus_tag="VVR39_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU6031176.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(1083..1643)
                     /locus_tag="VVR39_001753"
     CDS             complement(1083..1643)
                     /locus_tag="VVR39_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU6031177.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1737..2450
                     /gene="rsmG"
                     /locus_tag="VVR39_001754"
     CDS             1737..2450
                     /gene="rsmG"
                     /locus_tag="VVR39_001754"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU6031178.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            2704..3987
                     /locus_tag="VVR39_001755"
     CDS             2704..3987
                     /locus_tag="VVR39_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU6031179.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(4182..5753)
                     /gene="ffh"
                     /locus_tag="VVR39_001756"
     CDS             complement(4182..5753)
                     /gene="ffh"
                     /locus_tag="VVR39_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU6031180.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5765..6097)
                     /locus_tag="VVR39_001757"
     CDS             complement(5765..6097)
                     /locus_tag="VVR39_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU6031181.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(6187..6564)
                     /locus_tag="VVR39_001758"
     CDS             complement(6187..6564)
                     /locus_tag="VVR39_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU6031182.1"
                     /translation="MKIRMRNTIQFDEQLEVIDRLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            6636..7940
                     /locus_tag="VVR39_001759"
     CDS             6636..7940
                     /locus_tag="VVR39_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU6031183.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7953..8759
                     /gene="yidA"
                     /locus_tag="VVR39_001760"
     CDS             7953..8759
                     /gene="yidA"
                     /locus_tag="VVR39_001760"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU6031184.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(8815..8886)
                     /locus_tag="VVR39_001761"
     tRNA            complement(8815..8886)
                     /locus_tag="VVR39_001761"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8851..8853),aa:Arg,seq:cct)
     gene            complement(8929..9276)
                     /gene="rplS"
                     /locus_tag="VVR39_001762"
     CDS             complement(8929..9276)
                     /gene="rplS"
                     /locus_tag="VVR39_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU6031185.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(9395..9724)
                     /gene="crcB"
                     /locus_tag="VVR39_001763"
     CDS             complement(9395..9724)
                     /gene="crcB"
                     /locus_tag="VVR39_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6031186.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(9718..10092)
                     /gene="crcB"
                     /locus_tag="VVR39_001764"
     CDS             complement(9718..10092)
                     /gene="crcB"
                     /locus_tag="VVR39_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6031187.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLFKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(10089..10355)
                     /locus_tag="VVR39_001765"
     CDS             complement(10089..10355)
                     /locus_tag="VVR39_001765"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU6031188.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(10471..10914)
                     /locus_tag="VVR39_001766"
     CDS             complement(10471..10914)
                     /locus_tag="VVR39_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU6031189.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            11018..11953
                     /locus_tag="VVR39_001767"
     CDS             11018..11953
                     /locus_tag="VVR39_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU6031190.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            12007..12291
                     /locus_tag="VVR39_001768"
     CDS             12007..12291
                     /locus_tag="VVR39_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU6031191.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(12348..12566)
                     /locus_tag="VVR39_001769"
     CDS             complement(12348..12566)
                     /locus_tag="VVR39_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031192.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(12563..13457)
                     /locus_tag="VVR39_001770"
                     /pseudo
     CDS             complement(12563..13457)
                     /locus_tag="VVR39_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         3999 a         3051 c         2500 g         3930 t
ORIGIN      
        1 gttacccact acaaatatta tagagcctta taaatttgca acatagcaga taggtggggc
       61 aaaaacacaa ttttaggaga aaaagaagta aatcttccca tagtaaaacg cataatatca
      121 agttttcaca cctgatatta tgcgtttttc agattttaaa gacttttttc cagccttcat
      181 tttacatatg ttttaaacgt tcaatccgtt ctgagatagg tgggtgggta taaaagagtt
      241 tttggaaccc cccacctttc ttgggatcat tgatataaag ggcactgcta gcatcatcga
      301 cgtggcgact cataggtttg ctattgtcca acttatctag ggcattaatc attccctggg
      361 gattgcgagt cagctcgaca ctagatgcat ctgccagaaa ttccctctga cgagaaatag
      421 cgagctgaac caaggttgca gcgagaggtg ccagtacaat agctagtagg gaaaccacta
      481 gcataatgat ttcaagacca tttccatctc ggtcatcatc acttcgtctg cgacctgctc
      541 caccccacca catcatacga cctgccatac tagaaagcat ggtgatagca ctagcaaggg
      601 caactgcaat agtcgaaata cggatatcat aattacgaat atgactgact tcatgtccca
      661 taacagcttc tagttcttca cgattcatga tagctagtag acctgaagtc gcagcaacag
      721 ccgcattttg aggattagaa cctgtcgcaa aggcatttaa ggctggatca tcaatgatga
      781 aaacacgggg cataggaatc tgagcgacca gagccatatc ttccactaca tggtagaggt
      841 ctggtgccgt ttgctcatcc acctcacgcg ctccattcat ggacatgaca atctctgtcg
      901 attgaaaaat catagacaaa gcgtagataa agccgataat cagtgcgata accaaaccac
      961 caagtccaga tcttataaag agataaccaa ccgcataacc aacaagagct aagagtagga
     1021 aaaataccag caacaaaatc caggtttttc gtttattgct tgcaatttga tcaaacaaca
     1081 tcttagtcac ctaaaccgct aaaatcaact ttaggaaccg acttttcctc ttcaggtgtt
     1141 tgaaggaaat ctgccgcttt aaatccaaac attccagcga taatattgct cgggaaagtt
     1201 tctaatttta cattgtagtt gctgacaaca ctgttataga gttgacgaga gtaagaaatt
     1261 ttattttctg tatttgtcaa ctcctcttgc aatttaacaa agttagcact agctttcaaa
     1321 tctggatagc tttctgcaac tgcaaaaata cctgaaacct gacgagtgag ggcatcactg
     1381 gctttcatag cttctgctgg tgaagtcgct gccgccactt ggttacgtag ttctgccacc
     1441 ttttcaaggg tagaaccttc atatttggca taacctttta cagtctcaat caagtttggc
     1501 aagagatcat tgcgacgttt taactgaaca tcaatctgac tccaagcctc cttggtttgc
     1561 atacgatttt taaccaaacc gttatagcta acaatcacaa aaataacaac aagagctaaa
     1621 actccaagaa taatccaagt cataatataa gtcctttctg cttttagatt agtaccagta
     1681 tatcaaattt tctatgattg tggtaaaata agatgatact aaagaaggaa ataactatga
     1741 aaccaaaaac attttacaac ttgcttgccg agcagaatct tccactttcg gaccagcaaa
     1801 aagaacaatt tgaacgttat tttgagctct tggtcgagtg gaatgagaag attaatttga
     1861 cggcgattac ggacaaggaa gaagtttatc tcaaacattt ttacgattcg attgcaccca
     1921 ttcttcaagg tttgattccc aatgaaacta tcaaacttct tgatatcggg gctggggcag
     1981 gatttcctag tctaccaatg aaaattctct atccggagtt agatgtgacc attattgatt
     2041 cactcaataa gcgcatcaac ttcctacaac tcttggctca agaactggat ttgaacggag
     2101 ttcatttcta ccacggacgt gccgaagatt ttgcccaaga caagaacttc cgtgctcaat
     2161 atgattttgt aacagctcgt gcggttgccc gtatgcaggt cctatctgaa ttgactattc
     2221 cctaccttaa ggttggtggc aaactattgg cactcaaggc tagcaatgcg cctgaggaat
     2281 tattagaagc taagaatgcc ctcaatctcc tttttagtaa ggtcgaagac aatctcagct
     2341 acgccctacc gaatagagat ccgcgctata tcacagtggt agaaaagaaa aaagaaacac
     2401 caaataaata tccacgtaag gctggtatgc caaataaacg cccactttaa attttttagt
     2461 aaacaaatgt ttacaaaatc agcctcgctc ttttatttct aggctcggga aaaaatgatt
     2521 tacaaaatca tttttttctg ctatactatc ctaagcaaag gtttttaatg tcatcccgtg
     2581 aggtgacgaa gacgcagaaa tatttaaaac tctttaaaat ctaaatttta aagaagtctt
     2641 actctgaggg cctattgctg taaaataatg ggctcttttc tgatgcccaa aagtgaggtt
     2701 tatatgaaac aagaatcaac tgttgatttg ttactagacg ttgaccaacg tccttcggat
     2761 ggaaaaggaa ttctccttag cttccaacac gttttcgcca tgtttggtgc gaccatcttg
     2821 gtaccattga ttttgggaat gcctgtatct gttgcccttt ttgcttcagg tgttggaaca
     2881 ctcatctaca tgattgctac tggttttaaa gttccagttt atctaggttc ttcatttgcc
     2941 tttatcacag ctatgtcact ggctatgaaa gaaatggggg gggatgtatc tgctgcccaa
     3001 acaggggtta tcttgactgg tttggtctat gtccttgttg ctaccagcat ccgatttgta
     3061 ggaacaaaat ggattgataa actcttgcca ccaatcatta tcggtcctat gatcatcgtt
     3121 atcggtcttg gacttgcagg ttcagctgtt accaatgcag gtcttgtagc agacggaaat
     3181 tggaaaaatg ctctggtagc cgttgttact ttcctaattg ctgcctttat caatacaaaa
     3241 ggaaaaggct tcctacgaat cattccattc ctctttgcca ttatcggtgg ttacctcttc
     3301 gcactaactc ttggtttggt tgactttacg cctgtcctag aagctaactg gtttgaaatt
     3361 cctggtttct acttgccatt tagcacaggt ggtgccttta aagagtacaa tctttacttt
     3421 ggtccagaag ccatcgctat cttgccaatc gctatcgtaa caatttctga acatatcgga
     3481 gaccatactg ttttgggtca aatctgtggc cgtcaattct taaaagaacc aggtcttcac
     3541 cgtactctta ttggtgacgg tatcgcaact tctgtttccg ccttccttgg tggaccagcc
     3601 aatacaactt acggagaaaa tacaggggtt atcggtatga ctcgtatcgc ttctgtctca
     3661 gttatccgta acgctgcctt catcgcgatt gccctcagct tccttggtaa attcactgcc
     3721 ttgatttcaa ctattccaaa cgctgtactt ggtggtatgt caatccttct ctatggggtt
     3781 atcgccagca atggtttgaa agtcttgatt aaagaacgtg ttgatttcgc tcaaatgcga
     3841 aacctcatca tcgcaagtgc tatgttggtt cttggacttg gaggagctat ccttaaactt
     3901 ggtccagtta cactttcagg tactgccctt tcagccatga caggaatcat cttgaacttg
     3961 atcttgccat acgaaaataa agactaagag tctaaataca cctaatccac tcagacagct
     4021 gagtggattt ttcgtatacc ataataaaag tgtcttaaca aagttattaa aatcaaaaaa
     4081 cgtataatat cagatattct aaaaccttga tactgtacgt tttatcatag aaatttttac
     4141 tttattttct catcaaatga gatttgcatc aatctcttgt cttacttgcg tttcttcttc
     4201 gctttcttca ttttgttagc catacgtttc atggactgtt tcatagcaaa ttcaccaatt
     4261 ttacctttca aaccgccacc aaacatctgg ctcatatctg gcattcctgc tcctccgaga
     4321 gctgataagt caggcatacc gccttgtccc atcattcctt caagggcaga catatccatt
     4381 cctcccatat ttggcatatt tttaggaagg ttatttggat taatccccat ttgcttcatc
     4441 attttattca tatccccaga cataacaccc tgcatgagct gtttagcctg gttaaagtcc
     4501 ttgatgaatt tattgacttc gacgaatgta tttccagaac cagcagcaat acgacggcga
     4561 cggcttggat ttaacaaatc tgggttttca cgctcttcag gtgtcatcga agacacaatg
     4621 gcacgtttac gagcaatctg gcgttcatcc accttcatgt tttgaagggc tggattgttt
     4681 gccatacctg gaatcatctt gagcaagtct tccatcggcc ccatattttg cacctgatct
     4741 aattgatcga tgaaatcatt aaaatcaaag gtgttttcgc gcatcttctc agccatttca
     4801 agggcttttt gttcatcgta ttcctgagaa gctttctcaa tcaaagtgag catatccccc
     4861 ataccaagga tacggctaga catgcggtct gggtggaagg tttcaatgtc cgtaatcttt
     4921 tcacctgtac cagtgaactt gattggtttt ccagtaatgt gacgaacaga cagagcagca
     4981 ccaccacgag tatcgccatc aatcttggta aggatgaccc cagtcacttc caactgagca
     5041 ttaaactcac gcgcaacatt ggctgcttcc tgaccaatca tagcatcaac gacaagcaag
     5101 atttcatttg gttgagccaa tgctttcaca tcacgaagct cattcatgag gagctcatca
     5161 atctgcaaac gacccgcagt atcaatcaag acatagtcgt tatgattagt ttgggcttgc
     5221 tccaaacctt gacgtacaat ctcaacagct ggtacttctg ttccaagtgc aaagacaggc
     5281 acatcaatct gttgtcccaa ggtcttaagc tggtcaatgg cagctggacg ataaatatcc
     5341 gccgcaatca tcaaaggacg agcattttct tctttcttga gtttgttggc caatttacca
     5401 gcaaaggttg ttttaccagc cccttgtaaa ccaaccatca tgatgatggt tggaatctta
     5461 ggtgacttga taatttctgc cgtatcagaa cctaaaacgg ctgtcagttc ctcatcaacg
     5521 attttaataa tctgttgcgc aggattaagt gtatcaatga cctcatgccc gactgcacgc
     5581 tcacgaactt tcttgataaa gtcctttaca acaggcaagg caacgtcggc ctcgagcaag
     5641 gccaagcgaa tttctttggt tgcctcttgg acatcagatt cagagatttt tcctttttta
     5701 cgtagatttt taaagacgtt ctgcaaacgt tctgttaaac tttcaaatgc catttttctt
     5761 cctcttattc tctattatca atgcttgtta aaatttctat ctgctcctgc agaaaatcat
     5821 ccttgggata gcgctccaag atttggtcaa aaatctgact acggacaatg tagtccgagt
     5881 acatgtgcaa tttcatctca taatcttcca gaatcttttc tgttcgcttg atattgtcat
     5941 agacagcctg acgactaaca ccaaactcct cagctatctc agcaagactg taatcatcag
     6001 cgtagtaaag ctctatataa ttcatttgct tatctgtcaa aagcgccgca taaaattcaa
     6061 agagcgcatt catacgattg gttttttcga tttccataac ttttattata ccaaaaaata
     6121 gcctaatcta ccacactagg gagccaatcc ttgaagatag aaagtagatt tgagaaaaac
     6181 gagatcctag ccccaagtaa tttccaattg atagctggca aagggatgcc cctcttgatt
     6241 ttgtagttga taagctagct caatcttttg cctatcaact tgataacggc tcgtttgaat
     6301 gataaattcc tgcatgccca taggggtagg aatataggcc aaactatcac tatcctttaa
     6361 aaagcgcata atggtcttgg gattagaaaa tcggctcatc accagttctt gaccatgaaa
     6421 tttaatcact actttttcct tttcctcatt atagaaaagc aggtagctat aatctccttt
     6481 ttcatgcact tccacatcat aaagccggtc aatcacttcc aactgctcat caaactgaat
     6541 tgtatttcgc atccgaatct tcacatcagg ccctctttct tgtctcttgt cctactattt
     6601 taccaaaaag agcaggattt tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc
     6661 cagttcacaa ctacatccat gtcaataatc aaatcatcta tgacttgatt aatacaaaag
     6721 aatttcagcg tttgcgccgt atcaagcaac tgggaacctc cagttatacc ttccacggtg
     6781 gagagcacag ccgcttctct cactgtctag gagtctatga gattgcacga cgtatcacag
     6841 aaatttttga agaaaaatat cctgaggaat ggaatcctgc cgagtctctc ttgaccatga
     6901 ccgctgctct cctacatgac cttgggcatg gcgcctactc ccatactttt gaacatctct
     6961 ttgatacaga ccatgaagcc attactcagg agattattca aaatcctgag acagagattc
     7021 accaagtctt gctacaagta gcgcccgatt ttccagaaaa agttgccagt gtcatagacc
     7081 atacctatcc taataagcag gtcgtgcagc tcatttctag tcagattgac gcagatcgca
     7141 tggactatct cttgcgcgac tcctatttta caggagcatc ctatggggaa tttgacctga
     7201 ctcgcatcct ccgagtcatt cgtcctgtcg aaaatggtat cgcctttcag cgcaatggca
     7261 tgcacgccat cgaagactac gtcctcagtc gctaccagat gtacatgcag gtttatttcc
     7321 acccagcaac acgcgccatg gaagttctcc tacagaatct tctcaagcgc gccaaggaac
     7381 tctaccctga ggacaagaat ttctttgcac gaacttcccc acatctcctg cctttcttcg
     7441 aaaaaaatgt gaccttgact gactatctgg ctctggatga tggcgtgatg aatacctact
     7501 tccagctttg gatgactagt cctgacaaaa ttcttgcaga tttatctcaa cgctttgtca
     7561 accgcaaggt ctttaaatcc attacctttt cacaagagga ccaagatcaa cttactagca
     7621 tgagaaaatt ggttgaggac atcggctttg atcccgacta ctatactgcc attcataaga
     7681 actttgacct cccttatgat atctatcgtc ccgaatctca aaatccacgg acacagattg
     7741 agattttaca aaaaaatgga gaactggccg aactctctag cctgtctcct atcgtccaat
     7801 cccttgctgg cagtcgccac ggagataatc gcttttattt tccaaaagaa atgttggacc
     7861 aaaacagcat ctttgcaagc attacccagc aatttttaca cttgattgag aacgatcatt
     7921 ttaccccaaa taaaaactag aagaggaatt ttatgagtat taaactaatc gctgtcgata
     7981 ttgacggaac cctagtcaac agtcaaaagg agattactcc tgaagtcttt tctgccatcc
     8041 aagatgccaa agaagctggt gtcaaagtcg tgattgcaac tggccgcccc atcgcaggtg
     8101 ttgccaaact tctggacgac ttgcagttga gagaccaagg tgactatgtg gtgaccttca
     8161 atggtgccct tgtccaagaa actgctactg gccatgagat tatcagcgaa tccttgacct
     8221 atgaggatta tctggatatg gaattcctca gtcgcaagct cggtgtccac atgcatgcca
     8281 ttaccaagga cggtatctat actgcaaatc gcaatatcgg aacatacact gtacacgaat
     8341 caaccctcgt cagcatgcct atcttctacc gtacccctga agaaatggct ggcaaagaaa
     8401 ttgttaaatg tatgtttatc gatgaaccag aaattctcga tgctgcgatt gaaaaaattc
     8461 cagcagaatt ttacgagcgc tactccatca acaaatctgc tcctttctac ctcgaactcc
     8521 ttacaaagaa tgtagacaag ggttcagcca ttactcactt ggctgaaaaa ctcggattga
     8581 ccaaagatga aaccatggca atcggtgacg aagaaaatga ccgtgccatg ctggaagtcg
     8641 ttggaaaccc cgttgtcatg gaaaatggaa atccagaaat caaaaaaatc gccaaataca
     8701 tcactaaaac aaatgacgaa tccggcgttg cccacgccat ccgaacatgg gtactgtaaa
     8761 aggaaagaat agactaaaac cgctcagctg agcggttttt gatatctaat tacatgcccc
     8821 ctgcaggaat cgaacctgca actactcctt aggagggagt tgttatatcc attgaactaa
     8881 gggagctaga taaaaactct gctgaaaaag cagagttttt tagtcgaatt aacgacggat
     8941 ttctttgata cgagctgcct taccttgaag agcacgcaag tagtacaatt tcgcacgacg
     9001 tactttaccg taacgtacaa cttcgatttt ttcaacacgt ggagtgtgga ttgggaagat
     9061 acgctcaaca cctacaccgt tagagatttt acgaactgtg tagttttcag agatgccagc
     9121 acctttacgt gcaataacaa caccttcaaa aatctggata cgttcacggt taccttcgac
     9181 aactttcgca tgtacacgaa cagtgtcacc aggacggaat gatgggatat ctgtacgaag
     9241 ttgaccttca gtcaagcttt ggattaatgg attcatttta ttctcctatc tttgtcaatc
     9301 ttgaggaatc ttcctcagcg gataaactgt atttttgtgc gtccattaca cacaagatat
     9361 agtttaccaa atttctaaaa aaaagtaaag aaatttatag caaaattcct aaaaaaatcg
     9421 caaccaaacc acctatgtaa gtcaaagtca ggtaagaata aaagaccttc ttatcactta
     9481 gcagtctttg aagttcgtca ttcaaggtcg aaaaagttgt taaaccgcca caaaatcctg
     9541 ttgctagaat agcatatact tccttagact ctacatgatt gtaaaatact ccaattaaaa
     9601 aacaacctaa aagattagct atgagcgttc cgagtggcaa tttagaagct tgattatagc
     9661 gagaaaataa atagcgcact aaagctccga aaccacaagc aattgcaaga tagacgatta
     9721 ccatttcttc ctccctagaa aataagctaa gagtaggcct ccaccgatgc tcaaaagcaa
     9781 atacaggact aaactaaaat aacgccctgt atcaagcagc ttcacagtat caagcattag
     9841 gctggaaaaa gttgttaaac ctccgcaaaa acccgtcccc agtgctaaaa tcaagccctt
     9901 actagtcccc ttatagacca gatagccctt gaaaagaaaa atcaagcaga aaattcccag
     9961 atagttgaca aagagagtgc cccaaggaaa gtctggactg gctggtaacc aggtggaaac
    10021 tagatatcgg acaagtccgc ccaacatagc agctagaaaa attcctagcg gataaaattg
    10081 ttcttttttc atttgatatt ttgatcctga taatcacgcg aacgtttgag tatgtccgaa
    10141 aaagtcgcta caatagtctc ctgatagcgc ttgtcctcta cacgactccc aaccttttca
    10201 aaaataactt cttctctctt agtatctaaa atcggtttac ctgaagcttt cttataagca
    10261 accaccccct caactaaatg cattcgttct tctaacagtt tgacaatttg gtcgtcgatt
    10321 tgatcgattt cttgacgaat aatatctaaa tccatacagt ctcctccttt atttgaatta
    10381 ttgtatcaaa aagccatcaa ttaggctagt aaaatcccaa ctctcgataa gaaaaatgca
    10441 ctgattgatt acatcagcgc acttttatgc ttatcctact ttagcaacca attcttctgc
    10501 gaattgttcc aagcgttcaa tatcttcttc ctcggcagaa agatcaactt tgacacactc
    10561 agaacctttt tctgctcctg ttgaaacaaa gacacggtca aagtcatcaa cagccttaca
    10621 gaattcatcg tagaaggtat ctcctgagcc gaccactccg tagattttgc cattcaagtt
    10681 gagatctgct agatcttcgt agaagtccat catctcatct ggcaattcac catcaccata
    10741 agtataggtc gcaacgatag cgatgtctgc ttccaagaag tctgaagcgt caacagttgt
    10801 acattcatca acatcaacat ccaagcccaa gtcacgtaat ttgtctgcta caatatctgc
    10861 aatttcttcg gtattaccgg tcatactggc aaatacaatt tttgctaatg ccatatcgtc
    10921 ctcctcaatt tatctttctc cattatatca catctttttc attttaaaaa taaaaattct
    10981 tgtgctacaa tgaaatgaga aagaattgag gttatttatg gagatttgcc aacaaatttt
    11041 agaaaaaatt aaagaatacg acaccattat cattcatcgt catatgaaac cagaccctga
    11101 tgccttggga agtcaggtgg gattgaaagc cttgctggaa catcatttcc cagaaaaaac
    11161 catcaaagcc gtcggttttg atgaaccaac tcttacttgg atggctgaga tggatcttgt
    11221 tgaagataga gcctaccaag gcgcacttgt catcgtctgt gatacagcta atactgctcg
    11281 tatcgatgat aagcgctata gtcaaggtga ttttctcatt aagattgacc accatccaaa
    11341 tgatgatgta tacggtgacc tgtcttgggt cgatactagt tcaagtagcg ctagcgagat
    11401 gattacccta tttgcccaaa caacccaact agccttggca gatcgcgatg ctgagttgct
    11461 ctttgcagga attgtcggtg atacaggtcg cttcctctac ccttctacca ctgcacggac
    11521 tcttcgcctg gctgcttatt tgagagaaca taactttgac tttgcggctc tcactcgcaa
    11581 aatggacact atgagctaca aaattgctaa actgcaaggc tacatctacg accatctgga
    11641 agtggatgaa aatggtgctg ctcgcgttat cctgagtcaa gaagtcttga aacaatacaa
    11701 tgtaaccgat gctgaaactg cagccattgt cggtgcacct ggacgcattg acagagtgag
    11761 tctctgggga atttttgtcg aacaggctga tggccactac cgagttcgct tacgcagtaa
    11821 aatccatcct atcaatgaaa ttgccaagga gcatgatggt ggaggccacc ctctagcaag
    11881 tggtgctaat tcctatagcc tagaagaaaa cgaaatcatc taccaaaagt taaaaaactt
    11941 gcttaaaaac tgataaaata cttgccaaac ttttcagaat ctgatagact agtatggtaa
    12001 caatctatgg ctcgcaaaga gaccatggca gaaaggaaat attgcaaaat gaaaaaagat
    12061 atccatccag aatatcgccc agttgtcttc atggacacaa ctactggtta ccaattcctt
    12121 agcggttcaa caaaacgctc taacgaaaca gttgagttcg aaggcgaaac ttacccattg
    12181 atccgtgtgg aaatttcatc agactcacac ccattctaca ctggacgtca aaagttcact
    12241 caagcagatg gacgcgtgga tcgtttcaac aaaaaatacg gtctcaaata atgataaaag
    12301 aacagtttcg actgttcttt tttgtttctt gaaatcaact gctgttttca tgttccagac
    12361 tcatctgtag gttcggtttc catgctacta ggcaggaagg aaatagctgt ttcaacacgt
    12421 ccataatgag ctgtgctatt gtcacgaacc acactttcat tgatggtcca agtggaattc
    12481 attttcttaa aagcttctcg gactttttcc aaatctttgg aggcaatggc ctgctctaag
    12541 gtttcaaaac gaggacttat actcatctgc tttcacaaag cattctagtc catctccgat
    12601 taacgatgga ctttatcacc tccttctcca gtccttgtat gacatcttga agttgattca
    12661 tgatatcttc caaagttcga aaggctttat tcttaaatcc acgtttacga atctctttcc
    12721 acacttgttc aatggggttc atctctggtg tgtatggagg aataaatgca aaaccaatat
    12781 tagtcggaat ctttaaggta cttgatttat gccatatagc attgtccata acgaataaaa
    12841 gataatcatc tggataagct tgtgaaagct cttctaaaaa ggcgttcatc cactcagtat
    12901 tacatctacc agctattaag aaaaatgatt cgcctgtatg ggcatcaaca gctccataac
    12961 aatagcgaaa ttctcgtata tagtgactat ggacatgtgg acctactcct attggagacc
    13021 aacaagatcc cagtttactg attctaccga aaccagcctc atcttggtac atcaagcgaa
    13081 ccttatgaaa acgtctactg gttttaaagc gctttcttgt cttcttgaat tgagatttta
    13141 tttttagacg cgacaatggt ttgagcgtct gctttcttag gatgttctgg acgtggcata
    13201 atatttcgcc aaccatggcg cttcaacagt tgatagaagg catcacgtgt gtaggaacga
    13261 tataagcctg aaataaggta ttgtaacaaa ttctcctgcc tctgtagcct tcaaatggcg
    13321 ggcaagaaag gctttctctt cctcaactgt catatatgca tggttacgac caccacgtgt
    13381 ttcttgaagg agagagtcga gtccgaactc ctcatatttt ttacatttcg ccaaatcgtt
    13441 gtttgattac agtctatagt gtattgaatc tataatagta
//
LOCUS       DAVHSL010000055        13211 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000055 DAVHSL010000000
VERSION     DAVHSL010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.057"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..212)
                     /locus_tag="VVR39_001771"
     CDS             complement(<1..212)
                     /locus_tag="VVR39_001771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6031193.1"
                     /translation="MTLRTEDQVKDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEE"
     gene            complement(216..434)
                     /locus_tag="VVR39_001772"
     CDS             complement(216..434)
                     /locus_tag="VVR39_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031194.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(725..958)
                     /locus_tag="VVR39_001773"
     CDS             complement(725..958)
                     /locus_tag="VVR39_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEU6031195.1"
                     /translation="MKKDKEVYDNVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(1172..1492)
                     /locus_tag="VVR39_001774"
                     /pseudo
     CDS             complement(1172..1492)
                     /locus_tag="VVR39_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1440..3241)
                     /locus_tag="VVR39_001775"
                     /pseudo
     CDS             complement(1440..3241)
                     /locus_tag="VVR39_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767999.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(3408..3560)
                     /locus_tag="VVR39_001776"
     CDS             complement(3408..3560)
                     /locus_tag="VVR39_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031196.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            complement(3691..3894)
                     /locus_tag="VVR39_001777"
     CDS             complement(3691..3894)
                     /locus_tag="VVR39_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031197.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            4396..5595
                     /locus_tag="VVR39_001778"
                     /pseudo
     CDS             4396..5595
                     /locus_tag="VVR39_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(5974..6759)
                     /locus_tag="VVR39_001779"
     CDS             complement(5974..6759)
                     /locus_tag="VVR39_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6031198.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(6761..7580)
                     /locus_tag="VVR39_001780"
                     /pseudo
     CDS             complement(6761..7580)
                     /locus_tag="VVR39_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            complement(7582..8574)
                     /locus_tag="VVR39_001781"
     CDS             complement(7582..8574)
                     /locus_tag="VVR39_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6031199.1"
                     /translation="MKMITVEHLQKNFVKTIKEPGLKGAFRSFFHPKRQVFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQENRQGYVKDIGVV
                     FGQRTQLWWDLALQETYSVLKEIYDVPDAVFQKRMDFLNEVLDLKEFIQDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLG
                     DIEQLCDRIFMIDKGREIFDGTVNQLKKTFGKMKTLSFELHPGQDYIVSHFEGLSDIY
                     VTRQELSLDIQYDSSQYQTADIIQQTLSDFTIRDLKMTDANIEDIIRRFYRKEL"
     gene            complement(9591..10358)
                     /locus_tag="VVR39_001782"
     CDS             complement(9591..10358)
                     /locus_tag="VVR39_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEU6031200.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIVIPIFYNDDSELTEFPIEFFNKS
                     DAGFQHMIKTYDQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIASLFL
                     LYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEEYIN
                     RVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
     gene            complement(10459..12096)
                     /locus_tag="VVR39_001783"
     CDS             complement(10459..12096)
                     /locus_tag="VVR39_001783"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU6031201.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            complement(12164..12799)
                     /locus_tag="VVR39_001784"
     CDS             complement(12164..12799)
                     /locus_tag="VVR39_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEU6031202.1"
                     /translation="MTFPISEWKRNEEFDFFNKMDVPYLSMSSRIEVTQAINFHKKHS
                     ISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTSEDKLNFSSFTMGD
                     NLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVSTPMNLSKIDTVPRI
                     TWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKINEYFQKK"
     gene            complement(12796..>13211)
                     /locus_tag="VVR39_001785"
     CDS             complement(12796..>13211)
                     /locus_tag="VVR39_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031203.1"
                     /translation="EVKRFRDSRRNDSKSILLMDDNILTGRAMKNAAQKLSYRKYSVQ
                     FFHVRRLGLNRLSQVIQENSMNELQRYLTGIYKGGIFPAPYSKIKFGTNIAKQYLDEL
                     QIFTLSGDEILRLLYKNGLFSEESEVKVVRGNLYE"
BASE COUNT         4297 a         2496 c         1847 g         4571 t
ORIGIN      
        1 ctttcttctg attttgtttc aaggattatt gctacatcat tcatattttt aggtaaatac
       61 caaccatctg gcttatctga atatcccttg aagcctaatt gattaaaagt agttatttga
      121 ccagtacctt gattgatgtt ttcttcaact tcattaaagc ctaatacttc tcttgcataa
      181 tccttaactt gatcttctgt ccttaaagtc attttctatt cctcgtcact aaaattatct
      241 tcaaaactaa taatatcatt aggagtgcaa gataaagcct tacatattct ttctaaattc
      301 ttaaatgtaa ttggtttatc ctttcccatt tgtgccataa catttgttgt aagtcctgcc
      361 atagctatta catctgtttt ctttagtcct ttttttgcta actgtatcca taatggttta
      421 tagttaagtg ccataatatc cctctttttt tcttcattag atttatttaa ttatagcata
      481 aatattgatt tcattcaatc ttacattgat ttagtgattt gttttagaga atttgttgtg
      541 ttattccgtc cttattttgc cataaattgt tttaagtggg acctcttatc cttaccattt
      601 ttacctccta attttgagta taaaaaagac gatagagttt ttaatttcta tcgtctgaga
      661 tttacatatt aaattttcat cacaaaataa gactctttaa agaatcttta aattcattgg
      721 tatgctaatt acaatatcca ttattaaaat ggatactata agcagcacac caactattta
      781 ttttttgagt tttaaacttt ggtagaagtc ttgaactcct tatatttaca taactatttg
      841 cctctataac tattatgaca cgaaaccaac aagcaagttc aagcacctcc atatctttat
      901 tcaaatgagg actaagatat tcacaaacat tatcataaac ctctttatct tttttcataa
      961 aagaggcata caacttagca aatttatcct aaaatttttt gttgccttta tcaatcattt
     1021 caacgctcct ttaaatataa aaatgatcct atcaatcttt atattgagcc tattttctaa
     1081 ttgatacctt gcaagaaagg aataatagct gttcctatac caagtaggaa tgtaataaat
     1141 gcagaaagtc atatactgtc attcttttct attaaatcat tttgaagtgt ctcaaagcat
     1201 ccatgatggc ttcttctttt tcaggtgtac actgtggaat aatttgttta tcctttttag
     1261 acttgttgta atgttttcgt aattctattc cacatttctt ttttatctgt gcaatatata
     1321 atgtcgaaac ttttaattca aatttattcc aaacatattc tttgatttga gcatatgttg
     1381 ctttgctctc cgcacttgtc aaatccatct catccagctc aatttcaaca cttatatgct
     1441 tatcgacatc gagtttggac aaaagtgcta ccgtctcgac gtgtgttgtc tgtcccttga
     1501 gaatacaatt ttttatcctc gtcactgttt tgaggacaca atttatctgg ttctagttta
     1561 gcatttttac gtttactttt aaatttttta ccatccttgt tttgagtttc acctgttttg
     1621 aatattatgg ttaacattgc aggatcaatt tctccgtcga tattaacacc acctacaata
     1681 attttctcaa caatactttc aaaaactgta cgatcaaact ccgtaagcat tttctgtgaa
     1741 gatagcaagt gcttaaactc agttagtctt ttctttacat cgatttctga ttttaatgtt
     1801 gtttcaatat ttaccttctc ttctgctaga aactcttttt ctgaggaaat ttcattgtac
     1861 ttttcattgt atatggaatc gctaactttt ccttcgagcc ttagatttac aagattctcc
     1921 tcttttttta gtaatattcg aagtttgttt gtaatccttt ttagttcctt gttaaggcta
     1981 ttgtcattca attcagattc tatcgtttca agtaagtctg tcattaaatt ttcatttgaa
     2041 tgatagactt gtctgtaagc ttccaggaaa gccccctcaa tggcgatctc ttctaatcct
     2101 ttactatgct tacaaaattt ctttcctttc tttatcgatt ctttatcgat gtaacacagt
     2161 gccacacaac tttgcgataa tctgaacggc agtgccaact tcttctagat aatattgaac
     2221 cacaaaaacc acattccaac atgctactaa aagcatacat ttttgaatag cgttcacgct
     2281 tcccatttac attcgcagct gtcttcttat ttcctgctcg acgcaatcta atctcctgag
     2341 ctttttcaaa atcttcttta gatattattg gttcatgatt atccttgata tagtacttat
     2401 cttcttctcc aaaattactc aaccgtctct tgcttattgg gtcaactgta aaagtttttc
     2461 ccattagaat atcaccttta tatttttcat tctttattat tcctagaact gttgtatcat
     2521 tccagtgttc taaacctctt ggcgatttgt aaccaagttc atcaagttcc cttgcaatta
     2581 cttttcctcc aataccttct agataccttt caaaaatata acgaacaatt ttggcttctt
     2641 ttttattaat tgaaatctgc ttggtttcta catcataatc ataccctaag cacccttgaa
     2701 aaccaaccaa ttcaccacgt tgcatcttca tttttaatcc ttttttcaca tgggcagaag
     2761 tattctctac ttcttgctgt gcaacggagc ttagaatagt tagaagcaat tctccatcca
     2821 ttgttagggt atctatgttt tcttcctcaa aatatactcc aatttgcata tcctttaaca
     2881 ttctgacata cttcaaagta tctagggtat tccttgcaaa tctagcaatt gcttttgtga
     2941 caatataatc tatctctcca tttgcacaat cattgattaa tcgttgaaaa tcttgtctct
     3001 ttcctacttg tgttcctgaa ataccttcat ctgcataaat atctgccagc tcccaatctg
     3061 aacgctgaga aatatattct ttgtagtgtc ttacttgaga atcataactg tttttctgat
     3121 cctcactatc ggaactaact ctgcaataag cagcaaccct ctttaagtgt ctttctacat
     3181 tgtcgcctct tcgacgaact aaagaatcag cttttattat ttcaacatta ttttttttca
     3241 tactgaaatt cctccttttg attctatatt accgcattca aatcaaaaag tcagctattt
     3301 tgtgtactta atacgcagtt tgtttctaat cttgtcatac tcatttttag ataacatatt
     3361 tcttgagtat aaaaagttaa gcattgatag ttgcatagta tactttatta ctgattgttc
     3421 caaacttttt cctccttgta acatgtataa tttcctccgt gggtatgact ggttaaatca
     3481 ttcatgggca tttcacccgc tgtccttttt cgctggcagc ctgaacgttc agaagtatca
     3541 ttatccttat ttgtagtcat ggcagataga gaaccactct attttatagc taataattat
     3601 cgctcctatc acggcgtatc aagctaaagt gctcgacaaa taagaaagtc ccacctcggt
     3661 ttattcagtt ttcaaagggc ttaggattta ttaacaacta aacttatcca tctctaaaat
     3721 ataatctgta gttacctgat ataatttagc taattgtttc aaaaatgatg taggaatatc
     3781 ttgcttgcca ctttctattc tagaataagc agactgtgaa caatgaagat actgtgcaat
     3841 ttgacactgg gacaaatctt tgtcttctct taaattcttt aatctgatat acattaataa
     3901 tcctcttact aatattgtaa tttgaagatt atcaaatttg gaattttatg caaaatatgc
     3961 ataaaataat ttataagatt ttagaaatag ttggtataac agtaagtaag ctataagtta
     4021 ctaaaaaaag attttggaat aaactttttc atagcgataa aagcaccgta caagctagga
     4081 aaataataag taatcgccca atctgacctt ctccagaact tgattattcg tcaatcacta
     4141 cagttgacaa acatactaag attagtagtg aggaaatctc caacgggaga gagtactcat
     4201 tactttttct ttgtgttaaa atagtggtgt cttgttaagt catagagctc tctatggtgc
     4261 tagacgtcgc ttgacaaact ggcaagaaac ctgttttagg aagaatttta tcaaagtatg
     4321 tgggatacta gacgtcgagt attggaaata aaatcactaa aacaaggagt cattcaagac
     4381 aaaggggtaa acatgatgcg gacagttttc agaatggatg tgagtaaggc aagctcagaa
     4441 gtcgctattc ttgtgaatgg tgaaaaggtt catggctata ccatgcccaa tgatgccatc
     4501 ggatttagtc gtcttctaga ggatttgaaa taggtaaata cacctgagat tatcttcgag
     4561 gcacagacag gggtctattc tcgtcttcag gcctttctgg aggacaatag ctatgcttat
     4621 atacggctaa atcctttaaa actaagaagc aactagacag tttgcgagtc cgtaaaacca
     4681 atcagattga cgctgaaaag ctagcttcgt cacaattcat ccttaaccgc aaaccaactt
     4741 atgttcaaga agaagtctat caaaatttgc gtgacctcag tcgattctat cagaatctga
     4801 cagaagacat cgttaggact aagaatagcc tgcacaaggt gcttcaaatt gcctttccag
     4861 aaataaagaa ccttctctct actcctacag gggaacaata ttggaacctc gtgaccatct
     4921 ttccaaccaa gcattggagg ctgaaattat cagtagttga gctaaaagaa gccatcgtaa
     4981 ttcaacttct aaacggattt ctgagaacag agttggacga ttggctgaaa agttgagcga
     5041 gctggccgaa cagtcctatc ttgccatttc aaaaacctct cccatgacag aagaggttaa
     5101 gtatcatgca caggaactgt tgagactgac aaaccgcaag gatcaggact tagcacaaat
     5161 gattgaattg gctgaaccat tacctgaata cgagattctg ctctctattc ctggtatcgc
     5221 agaaacaaca gctacaagca ttattggcga attggagaca ttcgtcgctt tcagtctgcc
     5281 aaccaaatca atgcctttat cagtattgac ctcagacact atgaatctgg caatttccta
     5341 gctcaagaac atatcaccaa gcgtggaaat ccttacgcga gaaaaattct ctataagtgc
     5401 gtccacaata ttgcttcagc tagtcatacc aatccttgtc atatcgcgga cttttatgag
     5461 aaacgaaaaa gacaatcgca gacgacttca accaagccat atacgattgt ctctatacat
     5521 cgcctcatcc ggacaatgta ttacctcata acgcataaca aactttacga ctacacttta
     5581 acccaaagtc attaaagtca tctatgtcct atcattgtaa caccttattt tttaatacca
     5641 gataagtgtc ttttaagtgt gcccaaattt caaaaaacag ctcgcaatta tcttctaaac
     5701 attcctttga tactcattca gaaaaccttt tgagctagaa tatcgtatgt cccttaacaa
     5761 atggtatgta taaaagagct aaaaaaccac tcatgatatg aacgagtggt tatgactgaa
     5821 atattacata cctttgtatc atttttgcac aatggtcaaa tttcttgttt gaaaaactac
     5881 agtaagccta atcaaagctc tcaatgtatc attaaaactt ccttccaaag aataggaagt
     5941 tctatcaaaa ttcttaatta gattttactt cttctaagac cctgcgctct catatgcatc
     6001 caaacctttg ttccataatt ttaatgataa ggtaaaaaat attaatgaga taaggatcaa
     6061 tccaccaata ttgaacaatc catccttgtc tttcaagaaa tagctagctg ggtaataggc
     6121 tgtaaaagca aaaggaatga taaaactaat caaccaacgt aaaaacgaat ggtaaatcgc
     6181 aatcgggtat tttgcaaaat cattaaacat gtaaaaaata taaattattg ccccagattg
     6241 tttagtccaa aaagcaatac tagctgttac aatttttaaa gaggtataaa ttaaggttgc
     6301 aaagggaata ctgattaaaa agagaaaaac ctttgcccaa gtccaagtaa gactagttat
     6361 tgtcattaac agcaataaga cgcctactaa caattctcca agagcatcaa tttgaaacgt
     6421 ttctactaaa atatgaaaca aagggctaat gggtctagtc aaatacttat caaattctcc
     6481 tttacgaatt aaatgttgtc ctaaagccca cagattatca aaaaagagat ggtcaattcc
     6541 cttaggaatg agagaaaaac cataaataaa agcaacctga tgaaaactcc agccatcaag
     6601 taagggaata tgttgaaaca aaatatttag aaacagcatg tttaaccctt gtgtcaaaaa
     6661 gacacccaca acaccaacta aaaaatcagc cttatactcc ataatctgtt taagatattg
     6721 tcggataaaa atcaggtgca tgcgttgata tttcttcatt ctaacctcct tgaatagtta
     6781 tataattctg tacgcacttc caaatcagtt gggataaggc aatcataata aacagccaga
     6841 ataattgtag cgagagcgcc tgaatcattt gactcatgct atacttttct ataataacca
     6901 tcaccggggt atagattaaa gaagaaaatg gcaaaaaaga taatagttcg gcaataattt
     6961 ttggaaaaaa tgtcagagga accaaacttc cagataaaaa ggcaactaaa gaatttttca
     7021 aaagatttga tccccataag tttttaaaca caaaagctga aaaaccaaag caaatattga
     7081 aaaaaaaaat taatcaaaaa agctaagatt aagctaagaa ggtaaactgt ggttattaaa
     7141 acaatttgta agaaggactc acctgataag agctttagac ctgcaatcag aattacaaat
     7201 ggtagaccaa cactaacaaa aactagccat ctagacccaa tttctgtgaa aagataagac
     7261 attgcaaaat gaactggacg aagcagtcgc ataataatag agccatcctt tacttcccat
     7321 ccaatcataa aagaactatc tgattttgtc agtagattcg tcacaaaact catgatgata
     7381 tataaggtca tatcagataa agtaaaacct tgaatgagag actggtgaga tgaatcaaac
     7441 acagctttcc acaagtaaaa tgctacaaag gcccccatca catccccaat gcgataaaga
     7501 aaaaaattga cacgatacgt gattaattct tggattccag cgctaacaaa aggcttatag
     7561 cgtttccata atttagtcat cctaaagctc ctttcgatag aagcgacgaa taatatcttc
     7621 aatattcgca tccgtcatct ttaaatcacg gatcgtaaaa tcagacaaag tttgttgaat
     7681 aatgtcagcc gtttgatact gcgagctgtc gtactgaata tcaagtgaca attcctgtct
     7741 cgtcacatag atatcagaaa gtccttcaaa atgagagaca atataatcct gcccaggatg
     7801 tagttcaaaa gagagagtct tcatcttccc gaaagtcttt ttcagttgat tcacagttcc
     7861 atcaaagatt tctcggccct tatcaatcat aaaaatacga tcacataact gttcaatatc
     7921 acctaaatcg tgggtcgtta aaagtatggt cgtctcttct tcttgattaa tctgtgtaat
     7981 ggcacgtcga atattatcct tgaccgaaac atctaaacca atagtaggct catctaggaa
     8041 aagaactttc ggattatgca ataaggaggc cgcaatatcc gccctcatac gttgacctag
     8101 agatagagtt ctgacaggat cttgaataaa ttccttcaaa tctaaaactt catttagaaa
     8161 atccatgcgt ttttgaaaga ccgcatcagg aacatcataa atttccttta aaaccgagta
     8221 agtctcctgc aaagccaaat cccaccaaag ttgagttcgc tgcccaaaaa ctacaccaat
     8281 atctttaaca tagccttgac ggttctcttg aggaatcttt ccattgatac gacaaaaacc
     8341 tgatgttggt ttcaaaatcc ccgtcaacat cttgatagtt gttgatttcc ccgctccatt
     8401 tgcgccaata aagcctaaaa tttgtccttt gggcacctca aatgataaat ctttaacagc
     8461 ttcaaagact tgtctcttgg gatgaaaaaa agagcgaaaa gctcccttta agccaggttc
     8521 ctttattgtt ttcacaaaat ttttctgaag atgctctact gttatcattt ttataaatca
     8581 ctcctttcgt ttcactcaag ttataatatc aacaaaaatt gtagcatact acagtaaagt
     8641 taagaaaatt taccatcatt acaaaccata tgaaaaaagc tactaaaact atgccatctt
     8701 gtattttatc tgtaagtaag ctaaattact caagtacaaa gaattatgac gaagaacata
     8761 taaatttata attggataaa ctatagattt cagcaaacga agttatccca atataaaaat
     8821 actttaataa ctgaagatat tgacaggaag atattaaatt cctcattact atcctttact
     8881 atgcagtata attttaatat catttaccta cttccaagat gctgaaaaat actaagtcac
     8941 actattatga tgttattatt tccattttta ttttaacaga tgagtcaatt ctttcaacta
     9001 ccccctccct tataactata ttcatgaagt attcttgata ataaacctca tttaacttct
     9061 caaagtagtc agcttctgca actgctatta tctcataaca gattgatttg gtttcaataa
     9121 atggaagcta gaagccttgt cagctaccct gcacagttgg tgttttttca tttttctctt
     9181 caaaaaaatt ggtcggaagt tataataaaa aggtgatgtg tttgtggtga gttgaattaa
     9241 gagacaaact cactttgtct taacttttaa attgcctaac aaaaatacgg agattattct
     9301 ctaagcttta actgcaacat tatgtctcta caaccaacga taagtccaga aatctaccca
     9361 aataaccaaa caacctacat ttgttgaact ttgatgacaa gtaggaaatt ttacatttga
     9421 taaacactat tttgtacgca ttttgcacat aatttaacgt gctttccatc aatttagtta
     9481 aggacttaca tagaaaacaa tccgtttttg cttatgttaa attagtagaa ttagacaaaa
     9541 acaaaaccgc cattcgcact gttatatatt catttttagt acttactatt ctaaaaaaga
     9601 tatctatctt tcaattcctc aatttcttga ctacttattc ctagttctgt attaatatat
     9661 ctaagtattc ctccatattc tttatcaagg acattcaata ctcgattaat atattcttct
     9721 tttgctgaac tgagtgaaag taaattatgc atcaatatta cattcccact atggttattt
     9781 acatattcaa tattttcttt tctcacattt attaaatact tgttagatag taagtaatca
     9841 tgaaaaatat cgttcatatc tactcccaat atataaagca agaacaagct agctattcct
     9901 gttcgatcct tccccattga acaatgaaac aaaagagatt catcttttgg atgacttagt
     9961 aataatttaa agaatttctt gtaaccaagt ttactctgtt tttgattgat catttgatca
    10021 taagttttta tcatatgttg aaaacctgca tctgatttgt taaaaaattc tattgggaat
    10081 tctgtcaact ctgaatcatc attatagaat attggaatta ctatattttt tatatttttt
    10141 atatctggat ctggagcttt ttttatttca ttcgctgatc gaaagtcaat gacttttgtt
    10201 attccatagc tctgtaacaa atcgacatca attttagaga ttccaaatag tttacttgaa
    10261 cggaataatg ttttaggttt tattttttgt cctgtttgag tgaggtggtt tccaagatct
    10321 ctaaaattat attcttttag taaagttaga ttattcaatg cttttctcca taatatgctc
    10381 aaaaaaccat ctttatttta ttcaacatct ccggttgtta atttaaatta aaaaaggcta
    10441 ctttcgagta tttttgaatt atctactgga tgtttgttgc aattctaaaa cttcctcgtc
    10501 aatttttttc aaatcaatcc tatcaaacaa cattgataca tctgatagct tgttaggaag
    10561 gtttgaaata taattccaag tatttagctt tgttttaaac atatcctcaa tctttttacc
    10621 agaaaaagga atgaatggat ttaacatttg tcctaaatta agtataatga ttacacaagt
    10681 agctaagact tctttacatt tttcaatatc ggactctcgc aatgcccacg gtttcatatc
    10741 atcatagaat ttattagccg atctaatata ttcaaaaatt tcttctaatg cctgtttcat
    10801 atgcccgctc tcaactaaat tacctactgt tgtatataat tctttcaaat tatataaaat
    10861 ttctccttcg agatatttag tgggtatttc agattcaaaa tacttttcaa taaactttag
    10921 agtcctattg ataaaattac cgtacgatcc taataattct gagttatgac tataaataaa
    10981 ttctctccaa gaaaaatttg catctttcat ctcaggagca tttattgtta ggaagtatcg
    11041 gattgaatca gcatcatatt tttttatgat atcgttaagc catatagccc aattattact
    11101 tgttgatatt tttttgtttt ctaacgttaa atattcacta gaaataatat actctggaag
    11161 aggctctatt tctaaacctg agagtattgc cggccaaata atagtatgaa atgggatgtt
    11221 atcttttcca tgaacataat atgactttgt ccgattgttc caaaaatcag taatattatt
    11281 ttgaagtttt tgcgcccaat caacacttgc tgtgtagtaa cctgctaccg cttcaaacca
    11341 gacatatatt tttttatctc taaaaccatc aatgggaact ggaatcccat ttggtagatc
    11401 acgagtaaca gctcgatcag gtaaaccttc ccgtaaatac cttttagtta gatttattgc
    11461 attttttcgc catctcactg tttcttcagc atcatttaag taagtctcta acaaattttg
    11521 aaactcacta aaaacataat aaaagtgttc tgtctcacga acttctggtt cattggaaca
    11581 aatagaacat cttttatcaa ctaaatctat aggatctaaa attgctgagc aattatcaca
    11641 ttgatctcct cttgaatggg ttccacaatt cgggcatttt ccttcaacga acctatcagg
    11701 taagaattga ttatcaaatg tacaatagag ttgtttaatt ttttttgtat acaaaaattt
    11761 cttctcgtat aattgcaaaa ataattcttg tactatctca tgatgtagtg gagaatctgt
    11821 tcgcgagtac aagtcatatg taaaacctaa tttttcaaaa gtttctttaa attccttatg
    11881 ataaaaatca gcaatttctt tcacagactt attttctttt ttagctctga tagaaatagg
    11941 ggttccatta caatcacttc cagaaacata taaaacttcc tctcccttct gacgatagta
    12001 tcttgcaaga atatcccccg gtaaaagcgc tgccgcgtga ccaatatgta acgaaccgtt
    12061 tgcatatggc catgctcctc caataaaaat tgacatattg tatttctcct taaattcttt
    12121 atttttatta taacattatt taaatgcaat atcttttcaa tcattacttt ttttgaaaat
    12181 attcatttat tttatttaca aacctttgca ataacacaaa aaaattagat acgtgtaatc
    12241 catctcccat tccatgatta atttgtaaat tcactgtaca aaaatatctt tggttctctt
    12301 gaataacttt tccccacgtt attcgaggaa ctgtatcaat ttttgaaaga ttcataggag
    12361 tgcttacatg taaaaaatca atccatggaa cacaagaaag ataagcaatg ttattcttgt
    12421 caatatttgg tttttgccct tcttctgcct tctgtttatt tatgttgaac gcagaaacaa
    12481 attcaattaa attatctccc atcgtaaatg aagaaaaatt aagcttatct tccgatgtaa
    12541 gggtagtgaa agaacaacct ctttgattgt attgccagac aatctttccg tcggtatcca
    12601 ttagtaattc tggaatagaa tttattgcac tcataacaca ccacgatatt atggcataaa
    12661 gtgatatcga atgtttttta tgaaaattga tagcctgcgt tacttctatt cgtgaactca
    12721 tagataaata aggaacatcc attttattga aaaagtcaaa ttcttcattc cttttccact
    12781 ctgatatagg aaatgtcatt cgtataaatt cccccttacc actttcactt cactctcttc
    12841 tgagaacaag ccattcttat aaagtagtct taagatttca tctccagata gagtaaaaat
    12901 ttgtaattca tctaaatatt gtttagcaat attagtaccg aatttaattt ttgaatacgg
    12961 tgcaggaaaa atccctcctt tatatattcc tgttaaatac ctctgcaatt cattcattga
    13021 attttcttga ataacttgtg ataatctatt taggccaagc ctcctgacat gaaagaattg
    13081 gactgaatat tttcggtatg ataatttctg agcagcattt ttcatagccc ttcctgtcaa
    13141 aatattatca tccattaata agatactttt cgaatcattt ctccgactgt ccctgaacct
    13201 ttttacttca a
//
LOCUS       DAVHSL010000056        12988 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000056 DAVHSL010000000
VERSION     DAVHSL010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.058"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(130..618)
                     /locus_tag="VVR39_001786"
     CDS             complement(130..618)
                     /locus_tag="VVR39_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU6031204.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDVLNFEEFIRETEHSLNIREKN
                     TG"
     gene            complement(612..1080)
                     /locus_tag="VVR39_001787"
                     /pseudo
     CDS             complement(612..1080)
                     /locus_tag="VVR39_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1629..2306
                     /locus_tag="VVR39_001788"
     CDS             1629..2306
                     /locus_tag="VVR39_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU6031205.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2293..3090
                     /locus_tag="VVR39_001789"
     CDS             2293..3090
                     /locus_tag="VVR39_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU6031206.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3107..4210
                     /locus_tag="VVR39_001790"
     CDS             3107..4210
                     /locus_tag="VVR39_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU6031207.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4211..4291
                     /locus_tag="VVR39_001791"
                     /pseudo
     CDS             4211..4291
                     /locus_tag="VVR39_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4511..5530
                     /gene="galE"
                     /locus_tag="VVR39_001792"
     CDS             4511..5530
                     /gene="galE"
                     /locus_tag="VVR39_001792"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6031208.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5532..6497
                     /locus_tag="VVR39_001793"
     CDS             5532..6497
                     /locus_tag="VVR39_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6031209.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(6548..6754)
                     /locus_tag="VVR39_001794"
     CDS             complement(6548..6754)
                     /locus_tag="VVR39_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU6031210.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            6806..7282
                     /locus_tag="VVR39_001795"
     CDS             6806..7282
                     /locus_tag="VVR39_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU6031211.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7291..7962
                     /locus_tag="VVR39_001796"
     CDS             7291..7962
                     /locus_tag="VVR39_001796"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU6031212.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAVTYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPQVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8092..8430
                     /locus_tag="VVR39_001797"
     CDS             8092..8430
                     /locus_tag="VVR39_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU6031213.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8433..9062
                     /locus_tag="VVR39_001798"
     CDS             8433..9062
                     /locus_tag="VVR39_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU6031214.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9302..10453
                     /locus_tag="VVR39_001799"
     CDS             9302..10453
                     /locus_tag="VVR39_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6031215.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASTEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            10770..11519
                     /gene="truA"
                     /locus_tag="VVR39_001800"
     CDS             10770..11519
                     /gene="truA"
                     /locus_tag="VVR39_001800"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU6031216.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11509..12264
                     /locus_tag="VVR39_001801"
     CDS             11509..12264
                     /locus_tag="VVR39_001801"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6031217.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGIPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRTI"
     gene            12261..12722
                     /locus_tag="VVR39_001802"
     CDS             12261..12722
                     /locus_tag="VVR39_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6031218.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3710 a         2414 c         2863 g         4001 t
ORIGIN      
        1 atccttcgga taaattaatt gtctaacttt tggggggcag tacatttttg gtatatataa
       61 aatttgtagg agctatatct acaattttat attcccagtt tatggatgtc acttactata
      121 ttcacaatgt tatccagtgt ttttttctct aatatttaag gagtgttctg tttctcgaat
      181 aaattcttca aagtttaaca cgtcaacttg ttcctgaaca agaaaataat catccacgat
      241 ataaaattca tcagttaaat tagtagtata acttttatcg gctaattttt ttagcatgtg
      301 agcttcattt tttatatcat caagagctgt ccattctcct tcagcatcat aattcacaaa
      361 aggtcttgac tgcttgatga ttactttttg cccgtccgat tttctaattg cccgataaac
      421 atttccttta tttgatctct taataatttt ttccattttg tatttattta ttgcagagtc
      481 cttgcttgaa acttcacatg tggtttgaaa ataaatcctt ttttcttctt ctgaaaataa
      541 atccattttc cagctaggaa gactagggaa attttgtctc ttatcttcta catagttctt
      601 ccttttttca tctagcaata aatagatgac ttttttattt ttttcatcat aagcttgttt
      661 ttttaaaaaa gctccatatc tataatgaac tggagaatgc attccacatt gatagtcaga
      721 tagtattttt ggagccttaa attctgacag tctattcgta agattacaaa tcatactctt
      781 agcttcagat tctgacttag gatatagagt tataaatttg ttagcagtag ggctcatttc
      841 cctaggggaa ttaatttttt ttaattcctc taaattttta acaactttaa agctacaatt
      901 atttagttgg gatagtttat acacaatctt aaaaatattt acagcgtctt ttatttggga
      961 gcttatgtgt attttccacc cttgtgcagg caccttatct gataaataat agtaattcca
     1021 aatatcaccc tgttggaaat ttttatcaca ttttaaacat tctttctcta ataaatccat
     1081 aacaaactcc taattattaa aataggctag agacacagca ctagcctatt ccgtaagtaa
     1141 agctacttat tttatataaa atataactag cgacctgtaa ttaaacaagt aaaagaacaa
     1201 tacttaggga gacctgtgac aatgatatct tcctctggaa gtagttctaa ttcaaacaat
     1261 gtttgttcca tgactgtatc ctcctgttat gataaattcc agaaagcata gagcaaattc
     1321 gtggttcgtc tgactaaatt tcttatctga acaccacctt caaatacaaa ttttagtcaa
     1381 acttttattt tttctaactt tctaattata ttctaccatg tgcttttata tgtcaagaat
     1441 tttctgaata aactgtttat tttttatttt ttgacatttt tgcaaattgt ttaaaatctt
     1501 tcaattggat tcacttatta ctttaggaca ttgaaacttc tttcgccaga ggtgcttata
     1561 ttactgggaa gttgaagatt gaaatgtggt ataataagag gtaatagagt tttggaaagt
     1621 gagagaagat gatttcaaag agattagaat tggtagcttc ctttgtgtca cagggggcta
     1681 ttttactaga tgtgggaagt gaccatgctt atctgcctat cgagttggtt gagagaggcc
     1741 aaatcaaaag cgctattgca ggtgaggtgg tggaaggtcc ctatcagtct gcggttaaaa
     1801 atgttgaggc tcacggccta aaggagaaaa tccaagtccg tttagccaat ggcttggcag
     1861 cttttgaaga gactgaccaa gtgtctgtca ttaccattgc tggcatgggt ggtcgtttga
     1921 ttgctaggat tttagaagaa ggtttgggga agttagctaa tgtagagcgt ttgatcctcc
     1981 agcccaataa tcgtgaagac gacttgcgta tctggctaca ggatcatgga ttccagattg
     2041 tagcagaaag catcttagaa gaagctggaa agttttatga gattttggtg gtggaagcag
     2101 gacaaatgaa gctatcagcc agtgatgttc gctttggtcc cttcttgtcc aaagaagtca
     2161 gtccagtatt tgtccaaaaa tggcaaaaag aagctgagaa gctagagttc gccctcggac
     2221 aaatcccaga aaaaaatctg gaagaacgtc aagttctagt agataagatt caagctatca
     2281 aggaggtgct ccatgttagc aagtgaagtg atccaagctt atgaagcctt ttgccctcag
     2341 gaattttcta tggagggaga cagccgtggt ctgcaaattg gcactttaga caagggtatc
     2401 caaagggtca tggttgccct cgatattcgt gaagagacag tggcagaggc cattgaaaag
     2461 ggtgtggact tgattatcgt caagcacgcg cctatctttc gtcctatcaa ggacttgctt
     2521 gccagccgtc cgcaaaatca gatttacatc gacctgatta agcatgacat cgcagtttat
     2581 gtcagccata ccaatattga tatcgttgaa aatgggctca atgactggtt ttgtcagatg
     2641 ctagaaatcg aggagacgac ttatctgcag gaaacaggtc cagaacgtgg aattggacgt
     2701 attgggaata ttcagcctca gacattttgg gaattggccc aacaggtcaa gcaagtcttt
     2761 gacctagata gccttcgaat ggtgcattat caagagaatg atttgcagaa gcctatttca
     2821 agagtagcaa tttgtggtgg aagcgggcag tctttctata aggatgcttt ggcaaagggg
     2881 gcagatgtct atatcactgg tgatatctac taccatactg ctcaggatat gctgtctgat
     2941 ggcttgttag cattggatcc aggtcactat atcgaagtgc tttttgtgga aaaaatcgca
     3001 gcactcctta ctcaatggaa agagaaaaaa ggctgggaac tagagatttt acctagtcaa
     3061 gcatcgacca atcctttccg tcatatctag ttagaaagtg aagacaatga aaaaagttgc
     3121 cattattgga gcaggaattg tgggagcaac agctgcctac tacctctcga gagaaagtga
     3181 cctagaggtg accgtttttg accatgagca aggtcaagcc accaaggccg cagcaggaat
     3241 tatcagtcct tggttttcca aacgccgtaa taaagcctgg tacaagatgg cgcgcttggg
     3301 ggctgatttt tatgtggatt tattagctga tttagagaaa tcaggacaaa aaatcgactt
     3361 ttaccagcgt tcgggagtct ttctcttgaa aaaggatgaa tccaagttgg aagaacttta
     3421 tcaactggcc ctccagcgca gagaagaatc tcccttgata gggcaattag ccattctgga
     3481 ccaagcttca gctaatgaat tattccctgg tttgcaggga tttgaccgcc tgctctatgc
     3541 ttctggtgga gcgagagtag atggccaact cttggtaact cgtctgctag aagccagtca
     3601 tgtcaagctg gtcaaagaaa aagtgactct gacaccgtta gcatcaggct accagattgg
     3661 tgaagaggag tttgagcagg ttattttggc gacgggagct tggttggggg acatgttaga
     3721 gcctttaggt tatgaagtag atgttcgtcc tcaaaaagga caactacgag attatcagct
     3781 ggtccaagac atggaagctt accctgttgt catgccagaa ggggagtggg atttgattcc
     3841 ttttgcaggt gggaaattgt ccttaggcgc tacccacgaa aatgacatgg gatttgattt
     3901 gacggtagat gaaaccttgc tccaacaaat ggaggaggcg gccttgcctc attacccagt
     3961 tttagctaga gtgacttcaa gggctgagcg tgtgggaatc cgtgcctata ccagtgattt
     4021 ctctcccttc tttgggcagg tgccagaatt ggcaggtgtc tatgcagcca gtggactagg
     4081 ttcatcaggc ctcacaactg gtcctatcat tggttaccat ctagcccaac tgatccaaga
     4141 caaggagttg accttggacc ctctaaatta cccaattgaa aactatgtca aacgagtaaa
     4201 aagcgaataa tactcaatga aaatcaaaga acaaactagg aaactagccg cgggttactc
     4261 aaagcactgc tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga
     4321 ggttgtagat agaactgacg aagtcagtaa ccatacccat ggcaaggcga cgttgacgtg
     4381 gtttgaattg gattttcgaa gagtataagc attttactga aattttatca ggtagtttag
     4441 gatggcaaat gacattccct gtcaaaaatg gtaaaataag aaaaaataat ctgagaatcg
     4501 aggaaaaaag atgcaagaaa agattttggt aactggtggt gccggtttta ttggaaccca
     4561 cactgttatt gaattgatcc aagcaggcca tcaagttgtt gtggtggata atcttgtcaa
     4621 tagcaatcgt aagagtttag aagttgttga aagaatcaca ggagttgaga ttcctttcta
     4681 tgaggcagat attcgtgaca cagctaccct cagagatatt ttcaagcagg aagaaccgac
     4741 tggtgtcatt cactttgctg gtttgaaggc tgttggcgaa tcaacacgta tccctcttgc
     4801 ctactatgac aacaatatcg ctggaactgt cagccttttg aaagccatgg aagaaaacaa
     4861 ctgtaaaaac atcatcttca gttcttctgc gacagtttac ggggatccgc acacagtgcc
     4921 catcttggaa gatttcccac tttcagtgac caacccatac ggtcgtacta agctcatgct
     4981 agaggaaatt ttgactgata tttacaaagc agactcagaa tggaatgttg tcttgcttcg
     5041 ttactttaac ccaatcggag cccatgagag tggtgatttg ggagaaaatc caaacggtat
     5101 tccaaacaat ctcttgccat atgtgactca agtagccgtt ggaaaattag agcaagtgca
     5161 agtgtttgga gacgattacg atacggaaga tggaacaggt gttcgtgact atatccacgt
     5221 tgtcgatttg gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag gttcaggact
     5281 aaacgtttat aaccttggaa ctggtaaagg ttactcagtt cttgaaatta tccaaaacat
     5341 ggaaaaagcg gtgggacgtc ctattcctta ccgtatcgta gaacgtcgcc caggtgatat
     5401 cgctgcctgc tactcagacc cagcaaaagc taaagcagaa ctcggttggg aagcagaact
     5461 cgacatcacc caaatgtgtg aagacgcatg gcgttggcaa agcaagcatc caaatggatt
     5521 tgaagactaa gatgatgatt tcaatcatcg tcccttgttt aaacgaagag gaagtacttc
     5581 ctctttttta tcaggctctg gaagctttac ttccagattt ggaaacagaa atcgagtatg
     5641 tctttgtcga tgatggatca agtgatggga ccttggaact cttaaaggcc tatcgggagc
     5701 aaaatccggc agtccattat atttctttct ctcgaaattt tggcaaagaa gcagcccttt
     5761 atgcaggctt gcaatatgcg acaggagatt tggtggtggt gatggatgca gacctccaag
     5821 atcctcctag tatgttgttt gagatgaaaa atgtactaga caaaaatgta gacttggact
     5881 gcgttgggac acggagaact agtcgggagg gagaaccctt ctttcgcagt ttctgtgctg
     5941 ttctctttta tcgcctcatg caaaaaatca gcccagtggc tctgccgtcg ggtgtccgtg
     6001 attttcgtat gatgagaagg tctgtagtcg atgccatttt aagcttgacc gagtccaatc
     6061 gtttttcaaa ggggctcttc gcctgggtgg gtttcaaaac ctactatttg gactatccaa
     6121 atgtcgaaag gcaggctggc aagacaagtt ggagttttag gaaactcttt ttctactcca
     6181 ttgaagggat tattaatttt tcagattttc ccttgattat agcctttgta gctggtctcc
     6241 tatcttgttt tctttctctg ctgatgacct tttttgttgt ggttcggacc ctcattttgg
     6301 gcaatccgac atctggttgg acctctctga tggctgttat tctctttctt ggaggcattc
     6361 aactcttgac cattgggatt ctcggcaagt atatcagtaa gatttattta gagactaaaa
     6421 aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata
     6481 aagtgaaaag actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc
     6541 cattgattta ggcttcctgg tttccaatca gggcgcgagt tgggcaattt ttaacagcct
     6601 ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac
     6661 gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg
     6721 cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa
     6781 agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga
     6841 tcaagaagaa tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc
     6901 taatcgtatt ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat
     6961 cgttctcatc tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca
     7021 tgattctgat gcaagtgtag tacaaatctc atcttcaagc agttctcagc ctgagcagag
     7081 ttcagagcca gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat
     7141 taaagttctc gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc
     7201 tcagttagag gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg
     7261 tgatgttata aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt
     7321 cctgcttcca gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc
     7381 taccttgata caggagctat gtatcgtgca gtgacctata tggctcttaa gaaccaatta
     7441 ggagttgaag aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga
     7501 cgttcagaaa ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc
     7561 cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag caattcctca agtgcgtgag
     7621 aaactagttt ctctccaaca agaaattgcc cagcaaggcg ggattgttat ggatggtcgc
     7681 gatattggaa ctgttgtatt gccgcaagca gaattgaaaa ttttcctagt agcttctgtt
     7741 gatgagagag cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacctt
     7801 gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct
     7861 cctctcaaac aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa
     7921 gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag
     7981 attgatatcg gttttttcta aatttgtcaa aatgctgatt ttagggtata atagttgctg
     8041 ttcgagaaat tttgattttc aaagaatagt gaatgatgat aaggagaaat catgaacaat
     8101 ttaccaaatt gtccaaaatg taactcagag tatgtctacg aagacggtgc cctactggtt
     8161 tgcccagagt gtgctcatga gtggaatcct gctgaagttg cagaagtaga agaaggtctt
     8221 gtcgctatcg atgccaacgg aaataaattg gctgatggtg atacagtaac tctcatcaag
     8281 gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag ggacgcgcgt gaaaaatatc
     8341 cgcatcgtag aaggcgacca caatatcgac tgtaagattg atggttttgg tgccatgaaa
     8401 cttaaatcag agtttgtgag gaagatttaa gcatgtcaaa acactataaa cttgtatttt
     8461 atagccgtat cttcttgttt ctagcggctt ttacgggagt ttatcttgaa attactaggc
     8521 atggtggttt tgggatgctt ctctattaca cggttctgtc caacctcttg gtaactattt
     8581 ttacccttta tcttctaaag gttatgagcc gtgtaggtga aaattggcaa aggccaagtc
     8641 tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat tacctgtgtg atttaccatt
     8701 tcctcttggc gcccattgcg actaatttct ataccctaga aaatttcctt tgccactata
     8761 tcgttcccat ctggttttta gcggataccc tcttttttga caaacagggt caatacaaga
     8821 tttgggatcc agcagtgtgg accattttac cctttctgta tatgatgttt gctcttttta
     8881 atggcttggt tctaaaactc aatattccaa atgccaagga taatcctttc ccttacttct
     8941 ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg gtgtctgatt atctttgttg
     9001 cctatatggt agcaggattt attttctact ttatcaagca aatcaagaga aagtcatcct
     9061 aatactcttc gaaaatctct tcaaaccacg tcagtttcca tctgcaacct caaaacactg
     9121 ttttgaacaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagat
     9181 acaagggatt cattttcgaa tttaagaagg agtctacaaa ccaatgaggc ttcttctttt
     9241 cttgcttatt tgataactat caaaaaagta gaagattaag agaaatatag aaagagattt
     9301 catgaaacaa tttttagaac gggccagcat tttggctctc tccctcgttt tgattacctc
     9361 cttttccatt tcgagtgccc taccagccat gtttgactat tatcagggtt attctaagga
     9421 acaaattgag ctcttggtga gcttgccttc ctttggaatc atgatgatgt tactgctaaa
     9481 tggtttctta gaaaaaatat ttcctgagcg cttacagatt agtttgggct tgctgatttt
     9541 atcattgagc ggtacagctc ccttctggta ccaagcctat ccctttgtct ttggaacacg
     9601 gcttctcttt ggtttgggtc ttgggatgat caatgccaag gctatttcta ttatcagtga
     9661 acgctaccaa ggaaaaaggc gaattcagat gttagggcta cgcgcttcta cagaggtcgt
     9721 tggagcttct ctcattacct tggccgtcgg tcagttgttg gcctttggtt ggacagctat
     9781 ctttctagcc tatagtgctg gatttttggt gctgcccctt tatctgctct ttgtccctta
     9841 tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa gcaagtcgtt taactcgaga
     9901 aatgaaaggc ttgattttta ccttagctat cgaagcggca gttgtagttt gtaccaatac
     9961 agctattacc atccgtattc caagtttgat ggtggaaaga ggattggggg atgcccagtt
    10021 atctagtttt gttcttagta tcatgcagtt gatcgggatt gtggctgggg tgagtttttc
    10081 tttcttgatt tctatcttta aagagaaact gctcctctgg tctggtatta cctttggctt
    10141 ggggcaaatc gtgattgcct tgtcttcatc tttgtgggtg gtagtagcag gaagtgttct
    10201 ggctggattt gcctatagtg tagtcttgac gacggtcttt caacttgtct ctgaacgaat
    10261 tccagctaaa ctcctcaatc aagcaacttc atttgctgta ttaggctgta gtttcggagc
    10321 ctttacgacc ccattcgttc taggtgcaat tggcttacta actcacaatg ggatgttggt
    10381 ctttagtatc ttaggaggtt ggttgattgt aatctctatc tttgtcatgt acctacttca
    10441 gaagagagct taggattgat tcctaagttt ttcttttgat actcaatgaa aatcaaagag
    10501 caaactatag ttgattgagt ttggaatagt acgctgtagc tgctaaaata tttctagaaa
    10561 ttaatttgac tttcctaata gagttgttca tatcttattt caatctacta tagaaagcta
    10621 gccgcaggtt gctcaaaata gtgttttgag gttgcagatg gaaactgacg tggtttgaag
    10681 agattttcaa gagtataaga tttttatacc catacaatat ttgttttagg tccttgttta
    10741 cagactaatt tcttgataaa atagaggtta tgacgagata taaagcaact atttcctatg
    10801 atggttatgc ctttgctggc tttcagcgcc agcctcatgc gcgtagcgtt caggaagaaa
    10861 ttgaaaaaac cttgaccaga ttaaataaag ggcaagccat tactgttcac ggtgctggta
    10921 ggacagatag tggggttcat gccctgggac aggtcattca ttttgacctg ccttatcaga
    10981 tggatgagga gaaactccgt tttgccttgg atacccagtc tcctgaagat attgatgtga
    11041 tttcgattga gcttgtggca gatgattttc attgccgtta tgccaagcat agcaagacct
    11101 atgagtttac tgtggataga ggacgtccca aaaatccgat gcgccgtcac tatgccaccc
    11161 actttcccta cccactcgat gtggaacgaa tgcagattgc aatcaaaaag ctagagggaa
    11221 cccatgattt taccggtttt acagcctctg ggactagtgt agaggataag gttcgcacca
    11281 tcacagaagc tagtttaata gtcgatgaga caggacaatt tttgaccttt accttttccg
    11341 gaaatggttt cttgtataaa cagattcgca atatggtggg gactcttctc aaaatcggta
    11401 acaaccgcat gccagtagag cagattgatc tcatcttgga gaagaaggac aggcaacttg
    11461 caggtcccac tgcagcacca aatggtttgt atttaaagga gattcgttat gaagaataat
    11521 cgtattttag cactttctgg aaatgatatt tttagtggtg gtggactgtc agctgatttg
    11581 gctacctata ccttgaacgg cttgcatggg tttgtagcag tgacttgttt gacagccttg
    11641 acagaaaaag gatttgaagt ctttccaact gatgatacca tttttcaaca tgaattagat
    11701 agcttgcgtg atgtggaatt tgggggaatt aagattggtc ttctccctac tgtcagtgtg
    11761 gctgagaagg ccttggattt tatcaaacaa cgcccaggaa tacctgtggt gttggatcct
    11821 gtcttggtct gcaaggaaac gcatgatgta gctgtcagtg agctctgcca agagttgatt
    11881 cgctttttcc cttatgtcag tgtgattacg cctaatctcc cagaagcaga attattatcc
    11941 ggtcaggaaa ttaaaacctt ggaagacatg aaaactgcag cgcagaaatt gcatgattta
    12001 ggagcgccag cagtcattat caagggaggc aatcgtctta gtcaggacaa ggctgtggat
    12061 gtcttttatg atggacagac ctttactatc ctagaaaatc cagttatcca aggccaaaat
    12121 gctggtgcag gttgtacctt tgcctctagc attgccagtc acttggttaa aggtgataaa
    12181 cttttgccag ccgtagaaag ctctaaggct ttcgtttatc gtgctattgc acaagcagat
    12241 cagtatggag taagaacaat atgaagcaaa caaaaacaac taaaattgcc cttgtatccc
    12301 tattaaccgc cctttctgtg gttctaggtt atttcttaaa aatcccaaca cctacaggaa
    12361 ttctaactct tttagatgct ggtgtcttct ttgcggcctt ttactttggt agtcgtgaag
    12421 gagcggtagt cggaggacta gcaagtttct tgcttgacct cttatcaggc taccctcagt
    12481 ggatgttctt tagcttggtc aaccatggct tgcagggatt tttcgcagga tttaaaggaa
    12541 aaagtcagtg gttaggcctt attttagcaa ctattgccat ggtagggggc tacgccttgg
    12601 gttctacttt gatgaatggc tgggcagcag ccctcccaga aattctacca aattttatgc
    12661 aaaatatggc agggatgatt gtaggattta ttcttagtca aagtatcaag aagattaagt
    12721 aatactcttc gaaaatctct tcaaaccacg tcggcttcca tctgcaacct caaaacactg
    12781 ttttgagcag cctgcggcta gctttctagt ttgcactttg attttcattg agtataaaaa
    12841 gatcttggga aaagactcaa tttcagtaga aaaggaagta aatcttccca cattaaaacg
    12901 catattacca aggttcttat gaactgcacc ccaaaagtta gacagaaaaa atctaacttt
    12961 tggggtgttt ttattatgaa attgagtt
//
LOCUS       DAVHSL010000057        12669 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000057 DAVHSL010000000
VERSION     DAVHSL010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.059"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            30..1166
                     /gene="dnaN"
                     /locus_tag="VVR39_001803"
     CDS             30..1166
                     /gene="dnaN"
                     /locus_tag="VVR39_001803"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU6031219.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1231..1425
                     /locus_tag="VVR39_001804"
     CDS             1231..1425
                     /locus_tag="VVR39_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU6031220.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1509..2624
                     /gene="ychF"
                     /locus_tag="VVR39_001805"
     CDS             1509..2624
                     /gene="ychF"
                     /locus_tag="VVR39_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU6031221.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELNDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2695..3264
                     /locus_tag="VVR39_001806"
     CDS             2695..3264
                     /locus_tag="VVR39_001806"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU6031222.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3265..6774
                     /gene="mfd"
                     /locus_tag="VVR39_001807"
     CDS             3265..6774
                     /gene="mfd"
                     /locus_tag="VVR39_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU6031223.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6832..7098
                     /locus_tag="VVR39_001808"
     CDS             6832..7098
                     /locus_tag="VVR39_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU6031224.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7091..7459
                     /locus_tag="VVR39_001809"
     CDS             7091..7459
                     /locus_tag="VVR39_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU6031225.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7579..8847
                     /locus_tag="VVR39_001810"
     CDS             7579..8847
                     /locus_tag="VVR39_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU6031226.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8844..10121
                     /gene="tilS"
                     /locus_tag="VVR39_001811"
     CDS             8844..10121
                     /gene="tilS"
                     /locus_tag="VVR39_001811"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU6031227.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10125..10667
                     /gene="hpt"
                     /locus_tag="VVR39_001812"
     CDS             10125..10667
                     /gene="hpt"
                     /locus_tag="VVR39_001812"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU6031228.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10683..12641
                     /gene="ftsH"
                     /locus_tag="VVR39_001813"
     CDS             10683..12641
                     /gene="ftsH"
                     /locus_tag="VVR39_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU6031229.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         4365 a         1910 c         2573 g         3821 t
ORIGIN      
        1 taatactaaa aataaataaa ggagaatcca tgattcattt ttcaattaat aaaaatttat
       61 ttctacaagc attaaatact actaagagag ctattagttc taaaaatgcc attcctattt
      121 tatcaacagt aaaaattgac gtgaccaatg aaggtattac tttaattggt tcaaatggtc
      181 aaatttcaat tgaaaatttt atttctcaaa aaaatgaaga tgctggtttg ttaattactt
      241 ctttaggttc gatccttctt gaagcttctt tctttatcaa tgtagtatct agtttacctg
      301 atgtaactct tgattttaaa gaaattgaac aaaatcaaat tgttttaacc agtggcaaat
      361 cagaaattac cctaaaagga aaagatagcg aacaatatcc acgaatccaa gaaatttcag
      421 caagcactcc tttaatactt gaaacaaaat tactcaagaa aattattaat gaaacagcct
      481 ttgctgcaag tacacaagag agtcgtccga ttttaacagg tgtccacttc gtattgagtc
      541 aacacaaaga gttaaaaaca gttgcaacag actctcatcg cctaagccag aaaaaattga
      601 ctcttgaaaa aaatagtgat gattttgatg tcgtaattcc tagccgttct ctacgcgaat
      661 tttcagcggt atttacagat gatatcgaaa ctgtagagat tttctttgcc aataaccaaa
      721 tcctctttag aagcgaaaat attagcttct atactcgtct cctagaagga aactatcctg
      781 atacagatcg cttgattcca acagacttta acactactat tacttttaat gtggtaaact
      841 tacgccagtc aatggagcgt gcccgtcttt tatcaagtgc gactcaaaat ggtactgtga
      901 aacttgaaat taaggatggg gttgttagcg cccatgttca ctctccagaa gttggtaaag
      961 taaacgaaga aatcgatact gatcaggtta ctggtgaaga tttgaccatt agtttcaacc
     1021 caacttactt gattgattct cttaaagctt taaatagcga aaaggtgacc attagcttta
     1081 tctcagctgt tcgtccattt actcttgtgc cagcagatac tgacgaagac ttcatgcagc
     1141 tcattacacc agttcgtaca aattaagtga aagaggttga gcctggctcg cctcttttat
     1201 gatataatcg aaaaagaaaa ggagagtagt atgtatcaag ttggaaattt tgttgagatg
     1261 aaaaaatcac acgcttgtac aatcaagtcg actggtaaaa aggctaatcg ttgggaaatt
     1321 acacgtgtag gagcagatat caaaataaaa tgcagtaatt gtgagcatgt tgtcatgatg
     1381 gggcgatatg attttgagcg aaaaatgaat aaaattattg actgagaacc cttagttaga
     1441 gggttagcac tttatccctt tttgtgttat aatattaggg attgaaatga aaacggagaa
     1501 tgagaaatat ggctttgaca gcaggtatcg ttggtttgcc aaacgttggt aaatcaacac
     1561 tatttaatgc aattacaaaa gcaggagcag aggcagcaaa ctacccattt gcgacgattg
     1621 atccaaatgt tggaatggtg gaagttccag atgaacgcct acaaaaacta actgaaatga
     1681 taactcctaa aaaaacagtt cccacaacat ttgaatttac ggatattgca gggattgtaa
     1741 aaggagcttc aaaaggagaa gggctaggga ataaattctt ggccaatatt cgtgaagtag
     1801 atgcgattgt tcacgtagtt cgtgcttttg atgatgaaaa tgtgatgcgc gagcaaggac
     1861 gtgaagacgc ctttgtagat ccacttgcag atattgatac aattaatctg gaattaattc
     1921 ttgctgactt agaatcagtg aacaaacgat atgcgcgtgt agaaaagatg gcacgtacgc
     1981 aaaaagataa agaatcagta gcagaattca atgttcttca aaagattaaa ccagtcctag
     2041 aagacgggaa atcagctcgt accattgaat ttacagatga ggaacaaaag gttgtcaaag
     2101 gtcttttcct tttgacgact aaaccagttc tttatgtagc taatgtggac gaggatgtgg
     2161 tttcagaacc tgactctatc gactatgtca aacaaattcg tgaatttgca gcgacagaaa
     2221 atgctgaagt agtcgttatt tctgcgcgtg ctgaggaaga aatttctgaa ttgaatgatg
     2281 aagataaaaa agagtttctt gaagccattg gtttgacaga atcaggtgta gataagttga
     2341 cgcgtgcagc ttaccacttg cttggattgg gaacttactt cacagctggt gaaaaagaag
     2401 ttcgcgcttg gactttcaaa cgtggtatga aggctcctca agcagctggt attatccact
     2461 cagactttga aaaaggcttt attcgtgcag taaccatgtc atatgaagat ctagtgaaat
     2521 acggatctga aaaggccgta aaagaagctg gacgcttgcg tgaagaagga aaagaatata
     2581 tcgttcaaga tggcgatatc atggaattcc gctttaatgt ctaaaaatta ataaatggtg
     2641 tcaattaggt tggaaaaaaa ttccaaccct tttggctttt gaaaggaaaa ataaatgacc
     2701 aaattacttg taggcttggg aaatccaggg gataaatatt ttgaaacaaa acacaatgtt
     2761 ggttttatgt tgattgatca actagcgaag aaacagaatg tcacttttac acacgataag
     2821 atatttcaag ctgacctagc atcctttttc ctaaatggag aaaaaattta tctggttaaa
     2881 ccaacgacct ttatgaatga aagtggaaaa gcagttcatg ctttattaac ttactatggt
     2941 ttggatattg acgatttact tatcatttac gatgatcttg acatggaagt tgggaaaatt
     3001 cgtttaagag caaaaggctc agcaggtggt cataatggta tcaagtctat tattcaacat
     3061 ataggaactc aggtctttaa ccgtgttaag attggaattg gaagacctaa aaatggtatg
     3121 tcagttgttc atcatgtttt gagtaagttt gacagggatg attatatcgg tattttacag
     3181 tctgttgaca aagttgacga ttctgtaaac tactatttac aagagaaaaa ttttgagaaa
     3241 acaatgcaga ggtataacgg ataaatggtg accttattag atttattctc agaaaatgat
     3301 cagattaaaa aatggcatca aaatttaaca gataagaaaa gacaactaat acttggttta
     3361 tcaacatcta ctaaggctct tgcaattgca agcagtttag aaaaagaaga taggattgtg
     3421 ttattgacgt caacttatgg agaagcagaa ggacttgtta gtgatcttat ttctatcttg
     3481 ggtgaggaac tcgtctatcc atttttggta gatgatgctc ctatggtgga gtttttgatg
     3541 tcttcacagg aaaaaattat ttcacgggtt gaagccttgc gttttttgac tgattcatct
     3601 aagaaaggga ttttagtttg taatatcgca gcaagtcgat tgattttacc gtctcccaat
     3661 gcattcaaag atagtattgt aaaaatctca gttggtgaag aatatgatca acacgcgttt
     3721 atccatcagt taaaggaaaa tggctatcga aaagttactc aagtacaaac tcagggcgaa
     3781 tttagtcttc gaggagatat tttagatatt tttgaaatat cccagttaga accttgtcga
     3841 attgagtttt ttggtgatga aattgatggt atcaggtcat ttgaagtaga aacacaatta
     3901 tcgaaagaaa ataagacaga actcactatc tttccagcta gtgatatgct tttgagagaa
     3961 aaggattatc aacgaggaca gtcagcttta gaaaaacaaa tttcaaaaac tttatcacct
     4021 attttgaaat catacctaga agaaattctt tcaagttttc accaaaaaca aagtcatgca
     4081 gactctcgga agtttttatc tttgtgctat gataagacat ggactgtctt tgattatatt
     4141 gaaaaagata ctccaatatt ctttgatgat tatcaaaaat tgatgaatca gtatgaagtc
     4201 tttgaaagag aattagcgca gtactttaca gaagaattac agaatagtaa agcattttct
     4261 gatatgcagt atttttctga tattgaacaa atctataaaa aacaaagtcc agtgaccttt
     4321 ttctctaatc ttcaaaaggg tttaggaaat ctcaaatttg acaaaattta tcaattcaat
     4381 caatatccta tgcaggaatt tttcaatcag ttttcttttc taaaagaaga aattgaacga
     4441 tataaaaaaa tggattacac cattattctg cagtctagca attcaatggg aagtaaaaca
     4501 ttggaggata tgttagagga atatcagatt aaattggatt ctagagataa gacaaacatc
     4561 tgtaaagaat ctgtaaactt aatagagggt aatctcagac atggttttca ttttgtagat
     4621 gaaaagattt tattgataac tgaacatgag atttttcaaa agaaattaaa gcgtcgtttt
     4681 cgaagacaac atgtttcaaa tgcagagaga ttaaaagatt acaatgaact tgaaaaaggg
     4741 gactatgttg tccatcatat ccatgggatt ggtcaatatc taggaattga aaccattgaa
     4801 atcaagggaa ttcatcgcga ttatgtcagt gtccaatacc aaaatggtga tcaaatttct
     4861 atccccgtgg aacagattca tctactgtcc aaatatattt caagtgatgg taaagctcca
     4921 aaactcaata aattaaatga cggtcatttt aaaaaggcca agcaaaaggt taagaaccag
     4981 gtagaggata tagctgatga tttaatcaaa ctctactctg aacgtagtca gttgaagggt
     5041 tttgctttct cagctgatga tgatgatcaa gatgcctttg atgatgcttt cccttatgtt
     5101 gaaacggatg atcaacttcg tagtattgag gaaatcaaga gggatatgca ggcttctcag
     5161 ccaatggatc gacttttagt tggggatgtt ggttttggaa agactgaagt tgctatgcgt
     5221 gcagccttta aagcagtcaa tgatcacaaa caggttgtca ttctagttcc gacgacggtt
     5281 ttagcgcaac agcactatac gaattttaag gaacgattcc aaaattttgc agttaatatt
     5341 gatgtgttga gtcgctttag aagtaaaaaa gagcagactg caacacttga aaaattgaaa
     5401 aacggtcaag tcgatatttt gattggaaca catcgtgttt tgtcaaaaga tgttgtgttt
     5461 gctgatttgg gcttgatgat tattgatgag gaacagcgat ttggtgtcaa gcataaggaa
     5521 actttgaaag aactgaagaa acaagtggat gtcctaacct tgaccgctac gccaatccct
     5581 cgtaccctcc atatgtctat gctgggaatc agagatttat ctgttattga aactccgccg
     5641 actaatcgct atcctgttca gacctatgtt ttggaaaaga atgatagtgt cattcgtgat
     5701 gctgtcttgc gtgaaatgga gcgtggaggt caagtttatt atctttacaa caaagttgac
     5761 acaattgttc agaaggtttc agaattacag gagttgattc cggaggcttc gattggatat
     5821 gttcatggtc gaatgagtga agtccagttg gaaaatactc tattagactt tattgaggga
     5881 caatacgata tcttggtgac gactactatt attgagacag gggtggacat tccaaatgct
     5941 aatactttat ttattgaaaa tgcggaccat atgggcttgt caaccttata tcagttaaga
     6001 ggaagagtcg gtcgtagtaa tcgtattgct tatgcttatc tcatgtatcg tccagaaaaa
     6061 tcaatcagtg aagtctctga aaagagatta gaagcgatta aaggatttac agaattgggc
     6121 tctggcttta agattgcaat gcgagatctt tcgattcgtg gagcaggaaa tcttttagga
     6181 aaatcccagt ctggtttcat tgattctgtt ggttttgaat tgtattcgca gttattagag
     6241 gaagctattg ctaaacgaaa cggtaatgct aacgctaaca caagaaccaa agggaatgct
     6301 gagttgattt tgcaaattga tgcctatctt cctgatactt atatttctga tcaacgacat
     6361 aagattgaaa tttacaagaa aattcgtcaa attgacaacc gtgtcaatta tgaagagtta
     6421 caagaggagt tgatagaccg ttttggagaa tacccagatg tagtagccta tctgttagag
     6481 attggtttgg tcaaatcata cttggacaag gtctttgttc aacgtgtgga aagaaaagat
     6541 aataaaatta caattcaatt tgaaaaagtc actcaacgac tgtttttagc tcaagattat
     6601 tttaaagctt tatccgtaac gaacttaaaa gcaggcatcg ctgagaataa gggattaatg
     6661 gagcttgtat ttgatgtcca aaataagaaa gattatgaaa ttttagaagg tttgctgatt
     6721 tttggagaaa gtttattaga gataaaagag tctaaggaag aaaattccat ttgatatttt
     6781 tcttctataa aatagataaa aatggtacaa taataaattg aggtaataag gatgagatta
     6841 gataaatatt taaaagtatc gcgaattatc aagcgtcgta cagtcgcaaa ggaagtagca
     6901 gataaaggta gaatcaaggt taatggaatc ttggccaaaa gttcaacgga cttgaaagtt
     6961 aatgaccaag ttgaaattcg ctttggcaat aagttgctgc ttgtaaaagt actagagatg
     7021 aaagatagta caaaaaaaga agatgcagca ggaatgtatg aaattatcag tgaaacacgg
     7081 gtagaagaaa atgtctaaaa atattgtaca attgaataat tcttttattc aaaatgaata
     7141 ccaacgtcgt cgctacctga tgaaagaacg acaaaaacgg aatcgtttta tgggaggggt
     7201 attgattttg attatgctat tatttatctt gccaactttt aatttagcgc agagttatca
     7261 gcaattactc caaagacgtc agcaattagc agacttgcaa actcagtatc aaactttgag
     7321 tgatgaaaag gataaggaga cagcatttgc taccaagttg aaagatgaag attatgctgc
     7381 taaatataca cgagcgaagt actattattc taagtcgagg gaaaaagttt atacgattcc
     7441 tgacttgctt caaaggtgat aaaatggaaa atttattaga cgtaatagag caatttttga
     7501 gtttgtcaga tgaaaagctg gaagaattgg ctgataaaaa tcaattattg cgtttacaag
     7561 aagaaaagga aaggaagaat gcgtaaattc ttaattattt tgttgctacc aagttttttg
     7621 accatttcaa aagtcgttag cacagaaaaa gaagtcgtct atacttcgaa agaaatttat
     7681 tacctttcac aatctgactt tggtatttat tttagagaaa aattaagttc tcccatggtt
     7741 tatggagagg ttcctgttta tgcgaatgaa gatttagtag tggaatctgg gaaattgact
     7801 cccaaaacaa gttttcaaat aaccgagtgg cgcttaaata aacaaggaat tccagtattt
     7861 aagctatcaa atcatcaatt tatagctgcg gacaaacgat ttttatatga tcaatcagag
     7921 gtaactccaa caataaaaaa agtatggtta gaatctgact ttaaactgta caatagtcct
     7981 tatgatttaa aagaagtgaa atcatcctta tcagcttatt cgcaagtatc aatcgacaag
     8041 accatgtttg tagaaggaag agaatttcta catattgatc aggctggatg ggtagctaaa
     8101 gaatcaactt ctgaagaaga taatcggatg agtaaagttc aagaaatgtt atctgaaaaa
     8161 tatcagaaag attctttctc tatttatgtt aagcaactga ctactggaaa agaagctggt
     8221 atcaatcaag atgaaaagat gtatgcagcc agcgttttga aactctctta tctctattat
     8281 acgcaagaaa aaataaatga gggtctttat cagttagata cgactgtaaa atacgtatct
     8341 gcagtcaatg attttccagg ttcttataaa ccagagggaa gtggtagtct tcctaaaaaa
     8401 gaagataata aagaatattc tttaaaggat ttaattacga aagtatcaaa agaatctgat
     8461 aatgtagctc ataatctatt gggatattac atttcaaacc aatctgatgc cacattcaaa
     8521 tccaagatgt ctgccattat gggagatgat tgggatccaa aagaaaaatt gatttcttct
     8581 aagatggccg ggaagtttat ggaagctatt tataatcaaa atggatttgt gctagagtct
     8641 ttgactaaaa cagattttga tagtcagcga attgccaaag gtgtttctgt taaagtagct
     8701 cataaaattg gagatgcgga tgaatttaag catgatacgg gtgttgtcta tgcagattct
     8761 ccatttattc tttctatttt cactaagaat tctgattatg atacgatttc taagatagcc
     8821 aaggatgttt atgaggttct aaaatgaggg aaccagattt tttaaatcat tttctcaaga
     8881 agggatattt caaaaagcat gctaaggcgg ttctagctct ttctggtgga ttagattcta
     8941 tgtttctatt taaggtattg tctacttatc aaaaagagtt agagattgaa ttgattctag
     9001 ctcatgtgaa tcataagcag agaattgaat cagattggga agaaaaggaa ttaaggaagt
     9061 tggctgctga agcagagctt cctatttata tcagcaattt ttcaggagaa ttttcagaag
     9121 cgcgtgcacg aaattttcgt tatgattttt ttcaagaggt catgaaaaag acaggtgcga
     9181 cagctttagt cactgcccac catgctgatg atcaggtgga aacgattttt atgcgcttga
     9241 ttcgaggaac tcgcttgcgc tatctatcag gaattaagga gaagcaagta gtcggagaga
     9301 tagaaatcat tcgtcccttc ttgcattttc agaaaaaaga ctttccatca atttttcact
     9361 ttgaagatac atcaaatcag gagaatcatt attttcgaaa tcgtattcga aattcttact
     9421 taccagaatt ggaaaaagaa aatcctcgat ttagggatgc aatcttaggc attggcaatg
     9481 aaattttaga ttatgatttg gcaatagctg aattatctaa caatattaat gtggaagatt
     9541 tacagcagtt attttcttac tctgagtcta cacaaagagt tttacttcaa acttatctga
     9601 atcgttttcc agatttgaat cttacaaaag ctcagtttgc tgaagttcag cagattttaa
     9661 aatctaaaag ccagtatcgt catccgatta aaaatggcta tgaattgata aaagagtacc
     9721 aacagtttca gatttgtaaa atcagtccgc aggctgatga agaggaagat gaacttgtgt
     9781 tacactatca aaatcaggta gcttatcaag gatatttatt ttcctttgga cttccattag
     9841 aaggtgaatc aattcaacaa atacctgttt cacgtgaaac atccatacac attcgtcatc
     9901 gaaaaacagg agatgttttg attcaaaatg ggcatagaaa aaaactcaga cgtttattta
     9961 ttgatttgaa aatccctatg gaaaagagaa actctgctct tattattgag caatttggtg
    10021 aaattgtctc aattttggga attgcgacca ataatttgag taaaaaaacg aaaaatgata
    10081 taatgaacac tgtactttat atagaaaaaa tagataggta aaaaatgtta gaaaacgata
    10141 ttaaaaaagt cctcgtttca cacgatgaaa ttacagaagc agctaaaaaa ctaggtgctc
    10201 aattaactaa agattatgca ggaaaaaatc caatcttagt tgggatttta aaaggatcta
    10261 ttccttttat ggctgaattg gtcaaacata ttgatacaca tattgaaatg gacttcatga
    10321 tggtttctag ctaccatggt ggaacagcaa gtagtggtgt tatcaatatt aaacaagatg
    10381 tgactcaaga tatcaaagga agacatgttc tatttgtaga agatatcatt gatacaggtc
    10441 aaactttgaa gaatttgcga gatatgttta aagcaagaga agcagcttct gttaaaattg
    10501 caaccttgtt ggataaacca gaaggacgtg ttgtagaaat tgaggcagac tatacctgct
    10561 ttactatccc aaatgagttt gtagtaggtt atggtttaga ctacaaagaa aattatcgta
    10621 atcttcctta tattggagta ttgaaagagg aagtgtattc aaattagaaa gaataatctt
    10681 taatgaaaaa acaaaataat ggtttaatta aaaatccttt tctatggtta ttatttatct
    10741 ttttccttgt gacaggattc cagtatttct attctgggaa taactcagga ggaagtcagc
    10801 aaatcaacta tactgagttg gtacaagaaa ttaccgatgg taatgtaaaa gaattaactt
    10861 accaaccaaa tggtagtgtt atcgaagttt ctggtgtcta taaaaatcct aaaacaagta
    10921 aagaaggaac aggtattcag tttttcacgc catctgttac taaggtagag aaatttacca
    10981 gcactattct tcctgcagat actaccgtat cagaattgca aaaacttgct actgaccata
    11041 aagcagaagt aactgttaag catgaaagtt caagtggtat atggattaat ctactcgtat
    11101 ccattgtgcc atttggaatt ctattcttct tcctattctc tatgatggga aatatgggag
    11161 gaggcaatgg ccgtaatcca atgagttttg gacgtagtaa ggctaaagca gcaaataaag
    11221 aagatattaa agtaagattt tcagatgttg ctggagctga ggaagaaaaa caagaactag
    11281 ttgaagttgt tgagttctta aaagatccaa aacgattcac aaaacttgga gcccgtattc
    11341 cagcaggtgt tcttttggag ggacctccgg ggacaggtaa gactttgctt gctaaggcag
    11401 tcgctggaga agcaggtgtt ccattcttta gtatctcagg ttctgacttt gtagaaatgt
    11461 ttgtcggagt tggagctagt cgtgttcgct ctctttttga ggatgccaaa aaagcagcac
    11521 cagctatcat ctttatcgat gaaattgatg ctgttggacg tcaacgtgga gttggtctcg
    11581 gcggaggtaa tgacgaacgt gaacaaacct tgaaccaact tttgattgag atggatggtt
    11641 ttgagggaaa tgaagggatt atcgtcatcg ctgcgacaaa ccgttcagat gtacttgatc
    11701 ctgccctttt gcgtccagga cgttttgata gaaaagtatt ggttggccgt cctgatgtta
    11761 aaggtcgtga agcaatcttg aaagttcacg ctaagaacaa gcctttagca gaagatgttg
    11821 atttgaaatt agtggctcaa caaactccag gctttgttgg tgctgattta gagaatgtct
    11881 tgaatgaagc agctttagtt gctgctcgtc gcaataaatc gataattgat gcttcagata
    11941 ttgatgaagc agaagataga gttattgctg gaccttctaa gaaagataag acagtttcac
    12001 aaaaagaacg agaattggtt gcttaccatg aggcaggaca taccattgtt ggtctagtct
    12061 tgtcgaatgc tcgcgttgtc cataaggtta caattgtacc acgcggccgt gcaggcggat
    12121 acatgattgc acttcctaaa gaggatcaaa tgcttctatc taaagaagat atgaaagagc
    12181 aattagctgg cttaatgggt ggacgtgtag ctgaagaaat tatctttaat gtccaaacta
    12241 caggagcttc aaacgacttt gaacaagcga cacaaatggc acgtgcaatg gttacagagt
    12301 acggtatgag tgaaaaactt ggcccagtac aatatgaagg aaaccatgct atgtttggtg
    12361 cacagaatcc tcaaaaatca atttcagaac aaacagctta tgaaattgat gaagaggttc
    12421 gttcattatt aaatgaggca cgaaataaag ctgctgaaat tattcagtca aatcgtgaaa
    12481 ctcacaagtt aattgcagaa gcattattga aatacgaaac attggatagt acacaaatta
    12541 aagctcttta cgaaacagga aagatgcctg aagcagtaga agaggaatct catgcactat
    12601 cctatgatga agtaaagtca aaaatgaatg acgaaaaata accctgagag aggctggagc
    12661 ctctctttt
//
LOCUS       DAVHSL010000058        12586 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000058 DAVHSL010000000
VERSION     DAVHSL010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.060"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(191..538)
                     /locus_tag="VVR39_001814"
     CDS             complement(191..538)
                     /locus_tag="VVR39_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6031230.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKFLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(649..2424)
                     /gene="spxB"
                     /locus_tag="VVR39_001815"
     CDS             complement(649..2424)
                     /gene="spxB"
                     /locus_tag="VVR39_001815"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU6031231.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2631..4874)
                     /locus_tag="VVR39_001816"
     CDS             complement(2631..4874)
                     /locus_tag="VVR39_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6031232.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4884..5255)
                     /locus_tag="VVR39_001817"
     CDS             complement(4884..5255)
                     /locus_tag="VVR39_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU6031233.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5266..5661)
                     /locus_tag="VVR39_001818"
     CDS             complement(5266..5661)
                     /locus_tag="VVR39_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU6031234.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5845..5943
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6027..6818
                     /gene="thiD"
                     /locus_tag="VVR39_001819"
     CDS             6027..6818
                     /gene="thiD"
                     /locus_tag="VVR39_001819"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6031235.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7028..7660)
                     /locus_tag="VVR39_001820"
     CDS             complement(7028..7660)
                     /locus_tag="VVR39_001820"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6031236.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7653..8456)
                     /locus_tag="VVR39_001821"
                     /pseudo
     CDS             complement(7653..8456)
                     /locus_tag="VVR39_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
     gene            complement(8456..8980)
                     /gene="thiW"
                     /locus_tag="VVR39_001822"
     CDS             complement(8456..8980)
                     /gene="thiW"
                     /locus_tag="VVR39_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU6031237.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(8985..9677)
                     /gene="tenA"
                     /locus_tag="VVR39_001823"
     CDS             complement(8985..9677)
                     /gene="tenA"
                     /locus_tag="VVR39_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU6031238.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9688..10338)
                     /locus_tag="VVR39_001824"
     CDS             complement(9688..10338)
                     /locus_tag="VVR39_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU6031239.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10340..11725)
                     /locus_tag="VVR39_001825"
     CDS             complement(10340..11725)
                     /locus_tag="VVR39_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031240.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNLNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11726..12286)
                     /locus_tag="VVR39_001826"
     CDS             complement(11726..12286)
                     /locus_tag="VVR39_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6031241.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
BASE COUNT         3781 a         2802 c         2420 g         3583 t
ORIGIN      
        1 aaggattgga gaaggaggtg ataaagtcca tcgttaatcg gagatggact agaatgcttt
       61 ttgaaagcag atgagtatta tatgcaattt ctttatataa aaagaccgga ttgctccgat
      121 ctttcaatag ttcatattct caatttctat tttaaaaata gctaaggtta acgtcaaatg
      181 actacgcgac ctatttcata cgataaaaat caagcactag accagcaggt ccttgaacta
      241 ataaggactc tgttccccaa tcggttacag ttggtccgtg taaaaacttt ataccaagct
      301 cgttcaaccg tttgtagttc tggtctacat cctcaatctc gatatgaata atgattcctg
      361 actgaaagtt ttccaaagga accaaatgat tttgtgacaa cataaggcag tgactaccaa
      421 tcgtaaactg agcaaaacca tcatcagcat aatctgcctt tttatccaag atatgctcca
      481 agtcagcaca gacttgggga acatttgaaa cgataatatc taattgattt aaattcattt
      541 actctcctcc ataaaaagac cggattgctc cgatctttta aagttctgct ctatgaaaat
      601 caaagaataa agtctacaag tttcatattt gattttcggc gagaggaatt atttaattgc
      661 gcgtgattgc aatccttctt cttccaagaa gagacggaat ggtacgagtt cttctgcttc
      721 gtatttttcc ttgaaggctt tgatagcttc ttctgagtga agttttggat ccaattcaag
      781 tacttctact ggaagtggac ggtgttgagt gatgcgagca tcgatgacaa cagttttacc
      841 ttctttgttc aatttaacag cttctgcaac aactgcatcg atgtcttcga tacggtcaac
      901 tgtgaatcca acagctcctt gagcttccgc aattttagcg tagtcagcgt ttgtgaagtc
      961 tacaccaaac aagtgtttgt ttgtatcttc gtatttgttc ttgatgaagc cgtactcagc
     1021 atttgagaag acaaggttga taactggaag gtcgtattga acgtttgtga taacgtctgg
     1081 gtagcacatg ttgaatgctc cgtcacccat gatgttccat acttggcgat ctggattgtc
     1141 tttcttagca gcgataccac caggaagggc aatacccatt gtcgcaaaga gtggagatgt
     1201 acgccacatg ttcttaggtg tcatgtgaag gtgacgagta gatgtttgag tagtgttacc
     1261 tacgtcgatt gagtagatag cgtcttgatc agcatgtttg ttgattgcat tgtaaacttg
     1321 atacaattgc aattcaccct cagttttacc ttcgagtttg ttcatgtaat cacgccagtt
     1381 ttggttgttc ttaacgtttg cacgccacca tggagttgat tcaactgggt ttactttgtc
     1441 aaggatagct ttagctgctt gaccagcatc accaaggatt gaagcgtcaa gggcatgacg
     1501 tttaccaagt ttgtaagggt cgatatcgac ttggatgaat ttttcagtgt tcttgaatgc
     1561 ttcgtaaact tcagcaaatg ggaagtttga accaaggaaa agaactgtgt ctgcttcaaa
     1621 gaccacttcg ttggctggtt tccaaccaac acggtaagca gaacctgtca aaccttcata
     1681 gttccattcg aaagcttcaa agtttttacc agttgtgatg attggtgctt tgattttacg
     1741 tgacaattca gtaatcactt caccagcttt aacaccacca aatccagcat agataactgg
     1801 gcgttcagca ttgttcaaga tttcaacagc tttgtcgatt tcaacttcgt tcaaagcagg
     1861 agcgatgaat gagcgttcgt atgaacctga accgtagtat gagttttcgt cgatttcttg
     1921 gaaaccgaag tttactggaa tttcaacaac agctggacct tttttagaaa ttgcagcacg
     1981 gcaggcttcg tcaattactt ttggcaattg ctcagcgtaa gctacacgtt tgttgtaaac
     2041 agcgataccg ttgtacattg ggttttggtt aagctcttgg aaagcatcca tgttcaattc
     2101 gttaactgga cgcgatccaa ggatcgctag gaatggagtg ttatccatag ctgcatcgta
     2161 aacaccgtta atcaagtgag tcgcacctgg accacctgaa ccaactgcaa ccccgattga
     2221 gccgccgaat ttagcttgca taaccgctgc aagagcacct gtctcttcgt ggcgaacttg
     2281 taagaagcgg atatctttgt cttcagccaa agcgtccatc aatgagctga gtgttcctga
     2341 tgggataccg tagattgtat ctacgcccca tgttttcaat acgttaagca ttgctgcaga
     2401 tgcagtaatt ttcccttgag tcataatgat aactctcctt caattttttt agatttggag
     2461 aatacgatta catagaattg gaaacgttct ccaaattttt actattccac tgtatcatat
     2521 ttatgctgac ttttctaaaa atctgctcaa aactctctat tctctattct aatacagttt
     2581 tgaaagttct gtcatttctg ttttataaca aagaaatcta gtcattactt ttagtctatt
     2641 ttactaaaat ttaacagaag ggaactggtc agaacagata cagaactaaa ggccatggct
     2701 agacctgcca attctgggtt gagagccagt ccaacacctg aaaagactcc tgctgcaatc
     2761 ggaattccga caacattgta gataaaggcc cagaaaagat tgagtagaat tcgatgaaag
     2821 gttttcttac tcatgtcgaa ggcacgaacc actcctaaaa gattattggt tgtcaacacc
     2881 aaatctgctg actcgatggc gatatctgtt ccagctccca tagcaatccc cacatctgct
     2941 acactaaggg caggagcgtc attgataccg tccccaacaa aggctacttt ccctgactgt
     3001 tgcagtttat ggatttcatg ggctttttct tctggcaaga cgcctgcaat gacctcttca
     3061 attccgattt gatctgcaat agcacgcgcc acaccagcat tgtctcctgt cagcatgact
     3121 gttcggagac cacgtttttt tagctgactg atggctagct tagcattttc cttaggaata
     3181 tcttgcaaag caagcaagcc tttgatttca ttgtcaacag ctaagaacac aactgtctta
     3241 gcttcttttt ctagttcttc tagtttatct tgataagtat tagaaatatc cataccatcc
     3301 agcattttag catttccaag taaaacttgt tttccattga ttcgccctga aacacctttc
     3361 ccgtgcaagg actgaaaatt ttcaacagtt tgaaactcaa gtccagcttc actcgctcgc
     3421 ttaacgatag cctcagccag tgggtgttga gaagcatctt ccaaggaggc tgccaatcca
     3481 aacacttcta cttcgtcgcc gatgatatct gttaccacag gtttcccttc cgtcaaagtc
     3541 ccggtcttat caaagacaag agtttgaact ttctggattt cctgtaagac agttccattt
     3601 ttgaggagaa cccccatctt ggcactacgt cctgtcccca ccataagggc tgtcggtgtt
     3661 gcaagtccca aggcacaagg acaggcgata atcaaaaccg ccactccgta gagaagagag
     3721 gacacaaagc tagctccaag cacgaccaca ctatccctga gcaagacgaa ccaaacccaa
     3781 aaggtcatga ttcctaaaat gacaactact gggacaaaaa tccctgaaat cttatccgtc
     3841 aagtcctgaa tcggcgcacg acttgtctga gctttcttca caaaatccac aatctgagcc
     3901 aaaacagtct ctgagccaac tttttctgct ctaaagacaa gcgttccact atgattgatg
     3961 gttgagccaa tgacagtatc tccaactgtc ttgtccacag gcagactctc acctgtcacc
     4021 atggattcgt caatactaga gacaccttct actacgacac catcaacagc aatcttttca
     4081 ccgggacgca ctcgaatcag gtcgcctacc ttgacttgtt ccaaaggaac ttggacataa
     4141 ctatcatcac tcaagacttc tgcggtttta gcttgcaagt ccagtaattt ctccacagct
     4201 tgggacgtat tttttctcat tttttcctca aaaactgctc ccaaaagaac gaaaaagagg
     4261 ataaatccag cactttcgaa gtaaacaggg agaccagcaa agagagcaac taggctatag
     4321 aaataagcca ctagagttcc cagcgcaacc aaggtatcca tgttggcatt gtgcttttta
     4381 aaactggccc aagcactctg gatatatggc ttacctgcaa ctaacataat aggcgttgtt
     4441 gctagaaagg ttccccaatg catgacttga tgactaatgc tacctgtcaa catcccaatc
     4501 atgagaatca caagaggcac agtaaagata ctagtaatcc aaaaacgttg caggagagat
     4561 agagattttc gagtcttctc aacgactata tagcttccct tttgcatctt catgccacaa
     4621 gaaaattcat gtcgccctaa ttcttgaggt gtaaaacgaa tgactttctc ctcatctacg
     4681 ccgattggtt ccaagatacc ttcttcttca aacagaattt ccttataaca gtttgaagga
     4741 gtagcacgat gaaaggtaat ctcagctgga attccctttt gaagctggat atgggctgga
     4801 tgatagcctt tttcagctcg gatacggatt ttttgaatgc cattttctaa gcttgctttc
     4861 acaatttctg tcatagtctc cacctactct acaatcatct tgccgtgcat catgttcata
     4921 ccacaagcaa agccaaactc tccaacctgc tcaggcgtga tttccactac atactcttcc
     4981 cccattggca ggttcgcatg tacaccaaaa tctggaaaaa caatttgatc cagacatggt
     5041 gaaggatcct tgcggtcaaa gacaatgcgt gctggcactg atttcttgag gacaatcaac
     5101 tcaggagtat agcctcccat gacttccact cgaatctctt ggtatccgtt tttttgctgg
     5161 gctttttgtc cagatttttc aggctttttg aaaaaccaaa acaagataaa cgcgataagg
     5221 gcaatacaaa taatggttac aatactattt aacatgacgt ctcctttaca tacaattaca
     5281 tcttacttct gttacagcac ttgatttctt ctctgaaatc acagcttcca agtcttccaa
     5341 gtcagtctga gtaaattcac attctacaat caagtcagcc aacaaattcc taatcctacg
     5401 ggaacaaacc ttgtctttga tatcttggac aagtaaatcc cgactttggt ctagagttaa
     5461 aagggctgaa taaacaaagg acttgccttc ttttttccga gtcagacact ctttctcaac
     5521 caaacgagcc aaaagtgtct gaaccgtgga cttggaccag tcaaaccgct ctgccaaaac
     5581 cctaatcaaa tctgtactgg tctgctcccc ctgcatccaa ataatcttca tgacctgcca
     5641 ttctgcatct gaaatctgca ttaccatacc tccaaaatct acatttgtca attacactca
     5701 acagtatact cccaaaatct acatttgtca attatagaaa taatattttc ttcgaaaaat
     5761 agaattttaa tcatttgaaa aacgatttgc agtcaaatat tactatataa acaataaaaa
     5821 tatgctatac taaagaaaaa agaaaacaac cactaggggt gcgtaaagct gagattaacg
     5881 actgttagat ccctctgact caatctaggt aatgctagct gatggaagtg gaaatgataa
     5941 tggggactag cagtcttcta ttgcctttct aaaacagact agcttgttct taagaataca
     6001 aacttcagtt ggttgggagg ttttagatga cttatttacc cgttgctttg accattgcag
     6061 ggactgaccc tagtggtggt gctggcatta tggcagattt aaagtcattc caagcgagag
     6121 atgtctatgg aatggctgtt gtaaccagtc ttgtcgctca aaataccaga ggtgttcagc
     6181 taatcgagca cgtttctcct caaatgttga aagcccaatt ggagagtgtc ttttctgata
     6241 ttccacctca ggctgtaaaa actggaatgt tggctactac tgaaatcatg gaaatcatcc
     6301 aaccctatct taaaaaactg gattgtccct atgtccttga tcctgttatg gttgctacaa
     6361 gtggagatgc cttgattgac tcaagtgcta gagactatct caaaacaaac ttactacctc
     6421 tagcaactat tattacgcca aatcttcctg aagcagaaga gattgttggt ttttcaatcc
     6481 atgaccccga agacatgcag cgtgctggtc gcctgatttt aaaagaattt ggtcctcagt
     6541 ctgtggttat caaaggcgga catctcaaag gtggtgctaa agatttcctc tttaccaaga
     6601 atgaacaatt tgtctgggaa agcccacgaa ttcaaacctg tcacacccat ggtactggat
     6661 gtacctttgc tgcagtgatt actgctgaac tagccaaggg caagagtctt taccaggcag
     6721 ttgataaggc caaggccttt atcacaaaag ctattcaaga tgcccctcaa ctcggtcatg
     6781 gttctggtcc agtcaaccat acaactttta aagattaaga aaaaaaactc tctagttccc
     6841 actttaaggg aattagagag tttttatact cttcgaaaat ctcttcaaac tacgtcagct
     6901 tccatctgca acctcaaaac actgttttga gctgacttcg tcagtcttat ctaaaacctc
     6961 aaggcagtac tttgagcaac ctgcgactag ctttctagtt tactctttga ttttcattga
     7021 gtattaatta ggaaagaatg tcatgcaact ttgttaaaaa ggcttgcgtt tttgcctcaa
     7081 tatcttctgc ttgcatcaaa tcacgtacaa cagctacacc agctatgcca gtgcccataa
     7141 gctgatcaat attctctgat gtcaagccgc caatagcaac tactggaatg gcaaccgttt
     7201 gacaaattgt tttcaaggtt gaaatcaggg tgatgggtgc attttccttg gtggttgtcg
     7261 gaaaaatggc tcctgtcccc aagtaatctg cacctgattt ctccgcttcc agagctcttt
     7321 taaccgtttt agcggtgaca ccgaggattt tttcaggacc caagactttg cgagctaccg
     7381 aaactgggag ttcgtcatct ccaatatgca gaccagcagc atcaaccgca agacaaacat
     7441 ccaaccgatc atcgattatc aaggggacct gataggcatc tgttatttcc ttgacttgtt
     7501 ttgccagttg ataatattga ttggttgtga gatttttttc tcgcaattgg actatggtaa
     7561 cccctgaacg gcaggccgtc tcaacttttg caagaaagct ttccacggaa tcttgatagc
     7621 gattggttac cagatatagt ctaagcgctt ctctattcat aaacctctcc tttgatggta
     7681 tctagccaat tttcatctct tcttaggagc gaaagctgat tgagtacttg gtaacgaaat
     7741 tcttccaatc ccattccttg aacaactatt ttctcagcag cgatattgag ataagagact
     7801 gctaagcaag aagcttcaaa accagtcttt ccttggctga gaaaaacagc tgttaaggct
     7861 ccaaccaagt ctcctgtccc tgttatccag tctaattcag tacagccatt ctcaagtaca
     7921 gcaacttgat tctccgaaac aataaggtcc ttgggacctg tgactaagaa tgacatacca
     7981 ggataggtct gacaccagtc tttcaagact tgaagcaaat cctccgtttc ttaatcttta
     8041 gcactcgcat cgaccccaac gccgtggtgc tttaaaccaa caagacttcg aatttctgac
     8101 atgtttcctt taaggatcgt agggctatag tctaaaaggt ctctgactag tcccttacga
     8161 atgggcgacg ctgatacacc aaccgcatct actaccatcg ggagagaaga ttggtttgca
     8221 tacgaagctg ccatgcggat tgctttttcc ttctcagctg acaaatgccc caaattgatg
     8281 aagagagcct gactttgctt agtaaaatca agaacctcac ggggatcatc tgccatgaca
     8341 ggtttgcatc ccagagccaa aatcccattt gccagcatct cacaagaaat ctcattggtc
     8401 atacagtgaa tgagggaact agagcctata ggaaaaggat ttgtcaatgc ctgcatcatt
     8461 ctatcctttc agcaaagaaa tatccttgca cttttttaaa gaattcctgc ttgattaaaa
     8521 atctaaatgc aataaaggaa atcgctgtac caatcaaggt tgctccgaaa aatcgaggag
     8581 tgtagataaa ccaactaagc ttagcagccg atcctgtaaa gagcaccata acaggatagg
     8641 aaacaataga accaataata cctgttccca caatttctcc caaggcagaa aagtaaaatt
     8701 ttcgaccgta cttataaaag agacctgcta gaagggctcc aaaagtcgct cctgtgagag
     8761 ctaaaggcgg aatcccttga gtcgtcatac ggataaaggc tgtcactgta gccatagcca
     8821 aggcataaac aggtcccatc atgattcccg ctagaatatt gactacactg gacatcggtg
     8881 ccattccctc aatccgaaag ataggtgtaa ggactacatc aagggcaatc atcatagata
     8941 aaatggtcaa tttgtgaact tgtagttggt gctttctcat gtttctattc ttctcctttt
     9001 tctaaagact gtaaatcgct cttccatgtc tggtgttggt aggccatttc ccaaaacttg
     9061 gcttccatat gaacactgat gtggaaggca tctagcattt tttgcttatc tgtctcatca
     9121 ctttctcgat agagctgatt gaccagtgct ccctcctctc tgatctgttg ctctaactca
     9181 tccgtaatat aagtttcaat ccattgttga tagagaggat ttggtgatgg tttaagatta
     9241 agtgatttgc ctatatcatg gtataaccaa ggacaaggaa gcaagcttgc aaaagcgatg
     9301 gctaagttcg gctctgcaaa ttgcctataa atatgagaaa tgtaatgata acaggttgga
     9361 gcgattggat gttgctccat ttcctggtcg ctgatttcca attccttgaa aaattgttgg
     9421 cgaataaata actcaccctc cactaaaccc tgagcatttt gtttcaagag tcttttcatc
     9481 tcttggtttg aagtcttatc agccaaaaga tgatagattt ctgagaaggc cttcagatag
     9541 taggcatcct gaatcaggta atagcggaaa atggcaggtt ctaaattccc ctcttgtaat
     9601 tgtaaaataa agggatgatg aaaggaagcc tgccaagctt tcttggataa ttccatcgca
     9661 atatctgtaa attccataat aactccttta taaaaataga ctggtttgaa gcaataaaaa
     9721 gaaaagcagg tagattaatt ttgttttttt aggaatataa aaagtccgat agctattctt
     9781 caactgtgca tgttcgtcat atccgtgagc agatagagct ctcaggtaaa gatggcgcca
     9841 cctaaagact gtcatcagaa ccttactgta aatcaagggc gaccaaaaat gtagttcttg
     9901 accacgtaat aggcaagctt ctttgaggga cttgatttct tgctgaatga gaggaaaaga
     9961 attgaatacc acaatcaagg cataggacca agagcgtgat agcccctttt gagccaagta
    10021 caagagaagc tcttttagtg aaatagagga aacaaagaca aggccgatac aaactgtcac
    10081 aaaggccctc gttccaagca tgactgcctg tgaagcatct ccgtgtaact gaactgccca
    10141 gtagttggca aaagatggta aaatggcaag tatgatcatc caagctaaca ttttaaatcg
    10201 acggtaatag agcataaaga gaatacaaaa tgcgactacc gaaagattca gagcaatcga
    10261 aggaatgaaa gatgtttcca aggataaaat cagcaagaag agactgataa tcggtgtctg
    10321 ggttgctact ttgaccatac tatctcacct ccccttgggt attgctactc tgagatgtaa
    10381 gtggtttggt aatggtcact tctttcacat gccgaagacc ctgactagtc atctcaatcc
    10441 aataatcaac cacagaaatc aaagggtcta aacgatgact aatgagcaga aaacttcttc
    10501 cttgattcct ctcctccaca atccacttgc aaaaataatg gcaggctcta tcatccaaac
    10561 ctgcaaaagg ttcatctagc aagatcacgg aagccttact ggtcaagatg gtcaagagct
    10621 gaagaatttt ttgctgacca ccacttaatt gatagggact cttatcgact gcctgctcca
    10681 aatcaaaata tcgtaaagct tgaaaaatcc gctgatttct ttcagaatca ggtccatcta
    10741 attgaagctc ctctcgcaga ctgactcgga taaactgctt ctcagcttcc tgaacaacac
    10801 ccgtcagatc acggtacaaa ctctttttct ttttcaggac tgtccccttc catgcaatgc
    10861 gccccttata cttttgaaat tgaagaatag agcgaaagag ggttgatttc ccgacaccat
    10921 tgtcacccag gatacaggaa atcccttgat agaatgtgaa atcagcaatt gaaaagaggg
    10981 ggcgattacc aagctcacca gtcacacggt tcatatggaa tagttccggg ctagaagcaa
    11041 cttcctttga agcaacctgt gtcatctcat aggaagggat ttgaaacact tcccttagtt
    11101 ttccgtctct tagctcaacc atatagtcga tataggcttt atagtcagat aaatcatggt
    11161 cgcacaaaat gactgtcttc ccatcaagag ccaactcttt tagaatctcc aatatctcga
    11221 ttctactctt gcggtcaatg gaagcgaagg gctcatccaa gagatagacc ctaggattca
    11281 tggcaaagag gacagccagc gctgcttttt gcttttcccc acctgatagg tgatgaatgg
    11341 gacggtgtaa gattgcctcg caacgacatt gctggacaac ctctgctatt ttagaatcaa
    11401 tttcctgaag gtgatagccg atattctcca aggtgaaaat caactcctca aacaagttct
    11461 ccatggtaaa ttgatgattg agattttgca agagaatgcc aaccttctgg acacgtgcga
    11521 tgatagaaag ctgactgacc tcgctcccat ctatcaggac ttgaccacta tagggaagag
    11581 aactgacttg ggcaatcatt tgaaagaggc tggattttcc tgaaccactg ctcccaacta
    11641 acaaggtaaa ggcttgcgca tgaaaagtaa aatcaaacgg ctcagagaaa attggggact
    11701 gaatcgctcg tagttccaga cccatctatg cttttcctcc agttgcaaac tgatgataga
    11761 gtttgacaat ggcacgaacc aagatggtac agaagaaata aacagaaata aaacgtacca
    11821 caagcaagga aaggacaaac ggaagggaaa aggcgtagta acctaactta atgtattcat
    11881 agacaaagct aacaagcgta atcccaatac tattagcagt tagagagagc caactttcat
    11941 agcgattctt agttacgata aaaccaaatt cacttcccaa accttgaacc aagccagaca
    12001 aaagagctcc tagaccaaat tggctaccat aaaggacttc agcaagcgca gctagcactt
    12061 ctccaatcgt tgcacttccg actctcggaa caaagatggc agcaatgggc gcagccatac
    12121 accagagacc gaagaggatt tcattggcaa aggcctgcaa accaagaggt gttaagagta
    12181 gactgagaat attatacaca tatcctgaac caacgaaaac cccaccaaaa aagatagaca
    12241 agaaagcaag caagataaca tcttttaact gccatttttt caacataaaa aaactccttt
    12301 ttttaaagaa aagtggggca ctcaagaaga ccgacctaaa tactttgtat agcagactga
    12361 atttagaaca gtacacaaga acactaaaat atttctagaa attaatttga attttctaat
    12421 tgatttgttc gcatcttatt tcaatctact atatcatctt catccagttt cgtaaaagaa
    12481 aaaactctaa ttacagatac gaattagagt tcagcttaca agattagaca gttcttttcg
    12541 acatacgaaa aaaacatttc acatttccct tcgccagtct taactg
//
LOCUS       DAVHSL010000059        12115 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000059 DAVHSL010000000
VERSION     DAVHSL010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.061"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            712..1704
                     /locus_tag="VVR39_001827"
     CDS             712..1704
                     /locus_tag="VVR39_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6031242.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1706..2524
                     /locus_tag="VVR39_001828"
     CDS             1706..2524
                     /locus_tag="VVR39_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU6031243.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2526..3311
                     /locus_tag="VVR39_001829"
     CDS             2526..3311
                     /locus_tag="VVR39_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6031244.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3409..3627
                     /locus_tag="VVR39_001830"
     CDS             3409..3627
                     /locus_tag="VVR39_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU6031245.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3612..3809
                     /locus_tag="VVR39_001831"
     CDS             3612..3809
                     /locus_tag="VVR39_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031246.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(4235..4321)
                     /locus_tag="VVR39_001832"
                     /pseudo
     CDS             complement(4235..4321)
                     /locus_tag="VVR39_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4542..10976
                     /locus_tag="VVR39_001833"
     CDS             4542..10976
                     /locus_tag="VVR39_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU6031247.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDNNTSNEEARIKE
                     DSNQSQGDNAHSSANKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            11603..12079
                     /locus_tag="VVR39_001834"
     CDS             11603..12079
                     /locus_tag="VVR39_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6031248.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
BASE COUNT         4233 a         1816 c         2420 g         3646 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgaaatga tgaaagtctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaattt attggatttt
      241 ataatgagat tatttgtgag gaaaatagtt tcctacatgt acgaaagagg tggtcgagtt
      301 ggtttaggta gtcggtgcgt gagttgataa ttctcagggt atggacttct ttttcatgaa
      361 tgaggtaaaa gagcaggtat tgtttagaga caatcattct gagcatattt tctggataga
      421 gggagtatcc gattttatga tcaaagttaa taccgccctc tggtgagaag atgagtaggt
      481 tggtaattta aactattaaa cagaattttt gattaaaagt attatttcat gagagaaatc
      541 ctaatttcac aatccatagg caaactcttg catttcgttt tttattggac tataataggt
      601 tggtataaag ccttttgtag taataaaatg tagaaggtgt agaaagcaag gatttagaat
      661 atttgtagtt aaaaacacaa tgttgctatt ccttacgata gggagataga tatggcaatg
      721 atagaagtgg aacatcttca gaaaaatttt gtgaagactg ttaaggaacc gggcttgaag
      781 ggggctttgc gctcctttat tcatcctgaa aagcagacct ttgaagcggt caaggatttg
      841 acctttgagg ttccaaaagg gcagatttta ggatttatcg gggcaaatgg tgctgggaag
      901 tcgacaacca ttaaaatgct gacaggaatt ttgaaaccaa catctggttt ttgtcggatt
      961 aacggcaaga ttccccagga caatcggcaa gattatgtca aagatattgg cgtagtcttt
     1021 ggacaacgca cccagctatg gtgggatttg gctctgcaag agacctacac tgtcttaaaa
     1081 gagatttatg atgtgccaga ctcgctcttt cataagcgta tggacttttt gaatgaagtc
     1141 ttggatttga aggactttat caaggatccc gtgcggactc tttcactggg acaacggatg
     1201 cgggcggata ttgcggcctc cttgctccac aatcccaagg ttcttttttt agatgagccg
     1261 accattggtt tggacgtttc ggttaaggat aatattcgtc gggcaattac tcagatcaat
     1321 caagaggaag aaactaccat tcttttgacc actcacgatt tgagtgatat tgagcaactt
     1381 tgtgatcgga ttttcatgat tgacaagggg caagagattt ttgatggaac ggtgagccaa
     1441 ctcaaggaga cctttggtaa gatgaagact ctctcttttg aactgctacc aggtcaaagt
     1501 catctcgtct ctcactatga cggtctgtct gatatgacca ttgatagaca aggaaacagc
     1561 ctcaacattg aatttgatag ttctcgctac cagtcagctg acattatcaa gcaaaccctg
     1621 tctgattttg aaatccgcga tttgaagatg gtggatacgg atattgagga tattatccgt
     1681 cgcttctacc gaaaggagct ctaggatgat caaattgtgg agacgttata aaccctttat
     1741 caatgcaggg gttcaggagt tgattactta ccgagtcaac tttattctct atcggattgg
     1801 cgatgtcatg ggggcttttg tggcctttta tctctggaag gctgtctttg attcttcgca
     1861 agagtctttg attcagggct tcagtatggc ggatatcacc ctctacatca tcatgagttt
     1921 tgtgaccaat cttctgacta gatccgattc gtcctttatg attggggagg aggtcaagga
     1981 tggctccatt atcatgcgtt tgttgcgacc agtgcatttt gcggcctcct atcttttcac
     2041 cgagcttggt tccaagtggt tgatttttat cagcgttggc cttccatttt taagtgtcat
     2101 tgtcttgatg aaaatcatat cgggtcaagg tattgtagag gtgctaggat taactgtcat
     2161 ttatcttttt agcttaacgc tcgcctatct gattaacttt ttctttaata tttgctttgg
     2221 attttcagcc tttgtgttta aaaatctttg gggttccaac ctacttaaga cttccatagt
     2281 ggcttttatg tcggggagtt tgattccctt ggcattcttt ccaaaggttg tttcagatat
     2341 tctctccttt ttgccttttt catccttgat ttatactcca gttatgatca ttgttggaaa
     2401 atacgatgcc agtcagattc ttcaggcact ccttttgcag ttcttctggc tcttagtgat
     2461 ggtgggattg tctcagttga tttggaaacg ggtccagtcc tttatcacca ttcaaggagg
     2521 ttagtatgaa aaaatatcaa cgaatgcatc tgatttttat cagacaatac atcaaacaaa
     2581 tcatggaata taaggtggat tttgtggttg gtgtcttggg agtctttctg gctcaaggct
     2641 tgaatctctt gtttctcaat gtcatctttc aacatattcc attcctagaa ggctggacct
     2701 ttcaagagat agctttcatt tatggatttt ccttgattcc caagggaatg gaccatctct
     2761 tttttgacaa tctctgggca ctagggcaac gcctagtccg aaaaggggag tttgacaagt
     2821 atctgactcg tcccatcaat cctctctttc atatcctagt tgaaaccttt cagattgatg
     2881 ccttgggtga actcttagtc ggtggtattt tattgggaac aacagtgacc agcattgttt
     2941 ggactcttcc aaaattcctg cttttcctag tttgtattcc ttttgcgacc ttgatttata
     3001 cttctcttaa aatcgcaaca gccagtatcg ccttttggac taagcagtca ggcgccatga
     3061 tttacatctt ctatatgttc aatgactttg ctaagtatcc gatttctatt tacaattctc
     3121 ttcttcgttg gttgattagc tttatcgtgc ctttcgcctt tacagcctac tatccagcta
     3181 gctatttctt acaggaaaag gatgtgttct ttaacgtagg aggtttgatg ttgatttctc
     3241 tggttttctt tgttatttcc cttaaacttt gggataaggg cttagattcc tacgaaagtg
     3301 cgggttcgta aaagctaaag taagactaaa atcaagaaag gaacttatga tgtttgtaat
     3361 tgaagaagtc aaggatgaaa atcaaaaaag gcagttgtcg ctgaggtttt gaaggatttg
     3421 ccagaatggt ttggaatccc agaaagcaca caagcctata tagaaggaac cacgacactg
     3481 caagtttgga ccgcctatca ggagagtgat ttgactggat ttgtaaggtt atcctattcg
     3541 agtgaagatt gtgcagagat tgattgtctc ggcgtaaaaa agcttatcaa ggtagaaaaa
     3601 ttgggagcca attgcttgct actttagaga gtgaagctcg taaaaaagtt ggttatctgc
     3661 aggtcaaaac agtggcagaa ggttctaata aagattatga tcgaacaaat gacttttatc
     3721 gaggtcttgg ctttaaaaag ttagagattt tttctcagct atggaatccg caaaatcctt
     3781 gtcagatttt gattaaaaag cttgaataat attacttgac atctattctc agagtgctat
     3841 actgtaagtg taatcgccga tttagctcag ttggtagagc aaggcactcg taaagcctag
     3901 gttataggta gataaacgac tgaggagttg aaaaaataga taggtagaag ataaccgtta
     3961 agccttattc ttagcggtta tttatattgt ttaatagcgc tgatatttca tcaattatgc
     4021 ctgttttcgt gtttctggta gttgttcaag tttattgcta ctatttttga tggtatgaat
     4081 gtgcttataa tgtatcccgg ttaacgaaag ttttggactt atactcttcg aaaatctctt
     4141 caaaccacgt cagcgtcgcc ttgccgtata tatggttact gacttcgtca gttctatcta
     4201 caacctcaaa accatgtttt gagctgactt cgtcagtttc atctacaacc tcaaaacagt
     4261 gttttgagca acctgcggct agtttcctag tttgctcttt gattttcatt gagtactaat
     4321 cttatttttt aacgtgtgct aaaaaataaa ttaatgcagg ttaatttttc ttgaattaaa
     4381 tttttttaaa tgatatactg tttttatgga gagataacaa ttatatataa atgtactact
     4441 ctatttccta gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt
     4501 tattatctat tggaagttat ataaatatgt aaggaattaa aatgaaaaaa agtacagtat
     4561 tgtcattaac cacagctgca gttattttag cagcctatgc ccctaatgag gtagtcttag
     4621 cagacacatc tagctctgaa gatgctttaa gcatctctga taaagaaaaa gtagtagtag
     4681 ataaggaaac agaaaataaa gagaaacata aagatattca taatgctata gaaacttcaa
     4741 aggatactga agaaaagaaa acaacaatta ttgaggaaaa agaagttgtt agtaaaaatc
     4801 ctgtgataga caataacact agcaatgaag aagcaagaat caaagaagat tccaatcaat
     4861 ctcaaggaga taatgcacac tcgtctgcaa ataaaaacac agaaaatccc aaaaaagaag
     4921 ataaagttgt ctatattgct gaatttaaag ataaagaatc tggagaaaaa gcaatcaagc
     4981 aactatccag tcttaagaat acaaaagttt tatatactta tgatagaatt tttaacggta
     5041 gtgccataga aacaactcca gataacttgg acaaaattaa acaaatagaa ggtatttcat
     5101 cggttgaaag ggcacaaaaa gtccaaccca tgatgaatca tgccagaaag gaaattggag
     5161 ttgaggaagc tattgattac ctaaagtcta tcaatgctcc gtttgggaaa aattttgatg
     5221 gtagaggtat ggtcatttca aatatcgata ctggaacaga ttatagacat aaggctatga
     5281 gaatcgatga tgatgccaaa gcctcaatga gatttaaaaa agaagactta aaaggaactg
     5341 ataaaaatta ttggttgagt gataaaatcc ctcatgcgtt caattattat aatggtggca
     5401 aaatcactgt agaaaaatat gatgatggaa gggattattt tgacccacat gggatgcata
     5461 ttgcagggat tcttgctgga aatgatactg aacaagatat caaaaacttt aacggcatag
     5521 atggaattgc acctaatgca caaattttct cttacaaaat gtattctgac gcaggatctg
     5581 ggtttgcggg tgatgaaaca atgtttcatg ctattgaaga ttctatcaaa cacaacgttg
     5641 atgttgtttc ggtatcatct ggttttacag gaacaggtct tgtaggtgag aaatattggc
     5701 aagctattag ggcattaaga aaagcaggca ttccaatggt tgtcgctacg ggtaactatg
     5761 cgacttctgc ttcaagttct tcatgggatt tagtagccaa taatcatctg aaaatgaccg
     5821 acactggaaa tgtaacacga actgcagcac atgaggatgc gatagcggtc gcttctgcta
     5881 aaaatcaaac agttgagttt gataaagtta acataggtgg agaaagtttt aaatacagaa
     5941 atataggggc ctttttcgat aagaataaaa tcacaacaaa tgaagatgga acaaaagctc
     6001 ctagtaaatt aaaatttgta tatataggca aggggcaaga ccaagatttg ataggtttgg
     6061 atcttagggg caaaattgca gtaatggata gaatttatac aaaggattta aaaaatgctt
     6121 ttaaaaaagc tatggataag ggtgcacgcg ccattatggt tgtaaatact gtaaattact
     6181 acaatagaga taattggaca gagcttccag ctatgggata tgaagcggat gaaggtacta
     6241 aaagtcaagt gttttcaatt tcaggagatg atggtgtaaa gctatggaac atgattaatc
     6301 ctaataaaaa aactgaagtc aaaagaaata ataaagaaga ttttaaagat aaattggagc
     6361 aatactatcc aattgatatg gaaagtttta attccaacaa accgaatgta ggtgacgaaa
     6421 aagagattga ctttaagttt gcacctgaca cagacaaaga actctataaa gaagatatca
     6481 tcgttccagc aggatctaca tcttgggggc caagaataga tttactttta aaacccgatg
     6541 tttcagcacc tggtaaaaat attaaatcca cgcttaatgt tattaatggc aaatcaactt
     6601 atggctatat gtcaggaact agtatggcga ctccaatcgt ggcagcttct actgttttga
     6661 ttagaccgaa attaaaggaa atgcttgaaa gacctgtatt gaaaaatctt aagggagatg
     6721 acaaaataga tcttacaagt cttacaaaaa ttgccctaca aaatactgcg cgacctatga
     6781 tggatgcaac ttcttggaaa gaaaaaagtc aatactttgc atcacctaga caacagggag
     6841 caggcctaat taatgtggcc aatgctttga gaaatgaagt tgtagcaact ttcaaaaaca
     6901 ctgattctaa aggtttggta aactcatatg gttccatttc tcttaaagaa ataaaaggtg
     6961 ataaaaaata ctttacaatc aagcttcaca atacatcaaa cagacctttg acttttaaag
     7021 tttcagcatc agcgataact acagattctc taactgacag attaaaactt gatgaaacat
     7081 ataaagatga aaaatctcca gatggtaagc aaattgttcc agaaattcac ccagaaaaag
     7141 tcaaaggagc aaatatcaca tttgagcatg atactttcac tataggcgca aattctagct
     7201 ttgatttgaa tgcggttata aatgttggag aggccaaaaa caaaaataaa tttgtagaat
     7261 catttattca ttttgagtca gtggaagaaa tggaagctct aaactccaac gggaagaaaa
     7321 taaacttcca accttctttg tcgatgcctc taatgggatt tgctgggaat tggaaccacg
     7381 aaccaatcct tgataaatgg gcttgggaag aagggtcaag atcaaaaaca ctgggaggtt
     7441 atgatgatga tggtaaaccg aaaattccag gaaccttaaa taagggaatt ggtggagaac
     7501 atggtataga taaatttaat ccagcaggag ttatacaaaa tagaaaagat aaaaatacaa
     7561 catccctgga tcaaaatcca gaattatttg ctttcaataa ccaagggatc aacgctccat
     7621 catcaagtgg ttctaagatt gctaacattt atcctttaga ttcaaatgga aatcctcaag
     7681 atgctcaact tgaaagagga ttaacacctt ctccacttgt attaagaagt gcagaagaag
     7741 gattgatttc aatagtaaat acaaataaag agggagaaaa tcaaagagac ttaaaagtca
     7801 tttcgagaga acactttatt agaggaattt taaattctaa aagcaatgat gcaaagggaa
     7861 tcaaatcatc taaactaaaa gtttggggtg acttgaagtg ggatggactc atctataatc
     7921 ctagaggtag agaagaaaat gcaccagaaa gtaaggataa tcaagatcct gctactaaga
     7981 taagaggtca atttgaaccg attgcagaag gtcaatattt ctataaattt aaatatagat
     8041 taactaaaga ttacccatgg caggtttcct atattcctgt aaaaattgat aacaccgccc
     8101 ctaagattgt ttcggttgat ttttcaaatc ctgaaaaaat taagttgatt acaaaggata
     8161 cttatcataa ggtaaaagat cagtataaga atgaaacgct attcgcgaga gatcaaaaag
     8221 aacatcctga aaaatttgac gagattgcga acgaagtttg gtatgctggc gccgctcttg
     8281 ttaatgaaga tggagaggtt gaaaaaaatc ttgaagtaac ttacgcaggt gagggtcaag
     8341 gaagaaatag aaaacttgat aaagacggaa ataccattta tgaaattaaa ggtgcgggag
     8401 atttaagggg aaaaatcatt gaagtcattg cattagatgg ttctagcaat ttcacaaaga
     8461 ttcatagaat taaatttgct aatcatgctg atgaaaaggg gatgatttcc tattatctag
     8521 tagatcctga caaagatgct tctaaatatc aaaagcttgg cgagattgca gaatctaaat
     8581 ttaaaaattt aggaaatgga aaagagggta gtctaaaaaa agatacaact ggggtagaac
     8641 atcatcatca agaaaatgaa gagtctatta aagaaaaatc tagttttact attgatagaa
     8701 atatttcaac aattagagac tttgaaaata aagacttaaa gaaactcatt aaaaagaaat
     8761 ttagagaagt tgatgatttt acaagtgaaa ctggtaagag aatagaggaa tacgattata
     8821 aatacgatga taagggaaat attattgctt atgacgatgg tagtgcctta caatatgaaa
     8881 ctgaaaaact tgacgaaata aaatcaaaaa tttatggcgt tctaagccca tctaaagatg
     8941 gacactttga aattcttgga aagataagca atgtttctaa aaatgccaag gtatattatg
     9001 gaaatagcta taaatcgata gaaatcaaag cgactaagta tgactcacat tcaaaaacga
     9061 tgacatttga tttatacgct aatattaatg atattgtgga tggattagct tttgctggag
     9121 atatgcggtt ttttgttaaa gatgatgatc gaataaaagc tgaaactaaa attagaatgc
     9181 ctgaaaaaaa taaggaaact aaagcagaat atccgtatgt atcaagttat gggaatgtaa
     9241 tcgaattagg agaaggagat ctttcaaaga acaaaccaga caatttaact aaaatggaat
     9301 ctggtaaaat ctattctgat tcagaaaaac aacaatatct gttaaaggat aacatcattc
     9361 taagaaaagg ctatgcacta aaagtgacta cctataatcc tggaaaaacg gatatgttag
     9421 aaggaaatgg agtctatagc aaggaagata tagcaaaaat acaaaaggcc aatcctaatc
     9481 taagagtcct ttcagaaaca acaatttatg ctgatagtag aaatgttgaa gatggaagaa
     9541 gtacccaagc tgtattaatg tcggctttgg acggctttaa cattataagg tatcaagtgt
     9601 ttacatttaa aatgaacgat aaaggggaag ctatcgataa agacggaaat cttgtgacag
     9661 attcttctaa acttgtatta tttggtaagg atgataaaga atacactgga gaggataagt
     9721 ccaatgtaga agctataaaa gaagatggct ccatgttatt tattgatacc aaaccagtaa
     9781 acctttcaat ggataagaac tactttaatc catctaaatc taataaaatt tatgtacgaa
     9841 atccagaatt ttatttaaga ggtaagattt ctgataaggg tggttttaac tgggaattga
     9901 gagttaatga atcggttgta gataattatt taatctacgg agatttacac attgataaca
     9961 ctagagattt taatattaag ctgaatgtta aagacggtga catcatggac tggggaatga
    10021 aagactataa agcaaacgga tttccagata aggtaacaga tatggatgga aatgtttatc
    10081 ttcaaactgg ctatagcgat ttgaatgcta aagcagttgg agtccactat cagtttttat
    10141 atgataatgt taaacccgaa gtaaacattg atcctaaggg aaatactagt atcgaatatg
    10201 ctgatggaaa atctgtagtc tttaacatca atgataaaag aaataatgga ttcgatggtg
    10261 agattcaaga acaacatatt tatgtaaatg gaaaagaata tacatcattt gatgatatta
    10321 aacaaataac agacaagaca ctaaacatta agattgttgt aaaagatttt gcaagaaata
    10381 caaccgtaaa agaattcatt ttaaataaag atacgggaga ggtaagtgaa ttaaaacctc
    10441 atagggtaac tgtgaccatt caaaatggaa aagaaatgag ttcaacgata gtgtcggaag
    10501 aagattttat tttacctgtt tataagggtg aattagaaaa aggataccaa tttgatggtt
    10561 gggaaatttc tggtttcgaa ggtaaaaaag acgctggcta tgttattaat ctatcaaaag
    10621 atacctttat aaaacctgta ttcaagaaaa tagaggagaa aaaggaggaa gaaaataaac
    10681 ctacttttga tgtatcgaaa aagaaagata acccacaagt aaaccatagt caattaaatg
    10741 aaagtcacag aaaagaggat ttacaaagag aagatcattc acaaaaatct gattcaacta
    10801 aggatgttac agctacagtt cttgataaaa acaatatcag tagtaaatca actactaaca
    10861 atcctaataa gttgccaaaa actggaacag caagcggagc ccagacacta ttagctgccg
    10921 gaataatgtt tatagtagga atttttcttg gattgaagaa aaaaaatcaa gattaagaca
    10981 aaagctatag aaaaaaatgg tttatgtact gagattagat agtgaggtga tgacatagtt
    11041 ttgtgaaaac agccatttat aactcaatta tttagtttac ttcactattg atactatttg
    11101 gagttattaa tggacttagt ttagataact aatgaattga ttgcaagggt tagtattgac
    11161 aatattggtc atattgatta gaaaatagag tctatcaaaa tttaaaggct aatagaggtg
    11221 atgagacaat ttcaaggaat taagtagcgt ttggttgctt aattcctttt tatttggaag
    11281 gaagtttttc gtaaccgccc aataacgaag tctattggac ggttacgata tgatcactga
    11341 cttcgtcagt cttatctaca acctcaaaac tgtgttttga gcaacctgcg gctagcttcc
    11401 tagtttactc tttgattttc attgagtatt agaacagaaa aaatgcttgg agtatttgtt
    11461 tgtgtgttta tttttatata acaaactata aacaaaacaa aaatataaaa aaagagacaa
    11521 aaaagaacag aaagtaattg acaacggttt catatagtgt tatacttatg gcataaagtt
    11581 aatggaaaga agggaaaaac ttatggtatt agattatttc tttgacaaaa accttgtgtt
    11641 ttgcttagaa gcggataatc aagaacaact ctttgatcag gttgcaactt tattggaaga
    11701 acgagaaatt gtcactccaa cttatcgtga agccttgatc acgcgtgaaa agtcatttcc
    11761 aactggttta gatatggaat ttctaggaaa ggacttgcca aatgtagcga ttcctcatac
    11821 agatattgtt cataatctag ctgagaaagt ggtggttgtt cgattagaaa aaccagtaac
    11881 ttttcacaat atgatagctc ctgataagga agtagaagta tccctactct tctttattat
    11941 taacaattca agttcaagtc aaacaaatat tctggctcag ttgatggact ttttcacagg
    12001 aaatggacat cttgaagatt tatcaaaaat ttccgaacca gaaaaacttt atgcttacat
    12061 tgctgaagca accgcttaat cttgtctatt aaaaaataaa atcggaggaa atcca
//
LOCUS       DAVHSL010000060        11732 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000060 DAVHSL010000000
VERSION     DAVHSL010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.062"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..384
                     /locus_tag="VVR39_001835"
     CDS             <1..384
                     /locus_tag="VVR39_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6031249.1"
                     /translation="LNANGDMATGWLQNNGSWYYLNANGAMATGWAKVNSSWYYLNAN
                     GAMATGWAKVNSSWYYLNANGDMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYV
                     NGLGALAVNTTVDGYGVNANGEWVN"
     gene            complement(614..1594)
                     /gene="dusB"
                     /locus_tag="VVR39_001836"
     CDS             complement(614..1594)
                     /gene="dusB"
                     /locus_tag="VVR39_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU6031250.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1581..2453)
                     /gene="hslO"
                     /locus_tag="VVR39_001837"
     CDS             complement(1581..2453)
                     /gene="hslO"
                     /locus_tag="VVR39_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU6031251.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2618..4045
                     /locus_tag="VVR39_001838"
     CDS             2618..4045
                     /locus_tag="VVR39_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6031252.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRNLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLVDLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            4204..5712
                     /gene="glpK"
                     /locus_tag="VVR39_001839"
     CDS             4204..5712
                     /gene="glpK"
                     /locus_tag="VVR39_001839"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU6031253.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTTIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5754..7580
                     /gene="glpO"
                     /locus_tag="VVR39_001840"
     CDS             5754..7580
                     /gene="glpO"
                     /locus_tag="VVR39_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU6031254.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7650..8354
                     /locus_tag="VVR39_001841"
     CDS             7650..8354
                     /locus_tag="VVR39_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6031255.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8651..8854
                     /locus_tag="VVR39_001842"
     CDS             8651..8854
                     /locus_tag="VVR39_001842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031256.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8941..9447)
                     /locus_tag="VVR39_001843"
     CDS             complement(8941..9447)
                     /locus_tag="VVR39_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031257.1"
                     /translation="MRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMA
                     YQKNEIDLNISFRSYDPNVWNYVNTIHGNKQANTFANFMTGAGISYMIGRIGALLGGP
                     WGAIIGGAYFGIQAYQSYLDSQSPYPYYITSTYIHVVQRKWKFITEYYRNSNYTGYVK
                     TVTTYVNF"
     gene            10624..>11732
                     /gene="ltrA"
                     /locus_tag="VVR39_001844"
     CDS             10624..>11732
                     /gene="ltrA"
                     /locus_tag="VVR39_001844"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU6031258.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLG"
BASE COUNT         3464 a         2274 c         2690 g         3304 t
ORIGIN      
        1 ctcaacgcta atggtgatat ggcgacagga tggctccaaa acaacggttc atggtactac
       61 ctaaacgcta acggtgctat ggcaacaggt tgggctaaag tcaacagttc atggtattac
      121 ctcaacgcta acggtgctat ggcaacaggt tgggctaaag tcaacagttc atggtattac
      181 ctaaacgcta atggtgatat ggcgacaggt tgggtgaaag atggagatac ctggtactat
      241 cttgaagcat caggtgctat gaaagcaagc caatggttca aagtatcaga taaatggtac
      301 tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg tagatggcta tggagtcaat
      361 gccaatggtg aatgggtaaa ctaaacctaa tataactagt taatactgac ttcctgtaag
      421 aactttttaa agtattccct acaaatacca tatcctttca gtagataata tacccttgta
      481 ggaagtttag attaaaaaat aactctgtaa tctctagccg gatttatagc gctagagact
      541 acggagtttt tttgatgagg aaagaatggc ggcattcaag agactcttta agagagttac
      601 gggttttaaa ctattaagcc ttctccaatt gcaagagggc ttcaatctct gctagggtgc
      661 tagcttgcga aatggctcca cggagtttgg cagcgccaga tgttccacgg agatagtgag
      721 gagcgaggcc gcggaattca cgaactgcga cgttttctcc tttgaggtta atcaatcgtt
      781 tcaagtgttc gtaggcgatc ttcatcttgt cttcaaaggt caaatcaggt aggatttctc
      841 ctgtttcaaa gtaatggttg atttggttga agaggtaagg atttcccatg gcagctcggc
      901 caatcatgac tgcgtcagca ccaacttctt cgatgcgttg cttggcttct tggacagtac
      961 ggatatcacc gttggcgatg aatggaatct tggttagagc ttgggcaacc ttgtaaaggg
     1021 tctcaaggtc tgcgtggcca gtatacattt gttcacgggt acggccatgc atggcgaggg
     1081 cagaaacacc tgcagcctca gcagcgaggg cattttctac tgccagagat gggtccgccc
     1141 agccggtacg cattttgaca gtaagtggga tatcaaggac agactggacc ttgttgatga
     1201 tagagtagat cttgtcagga tccttgagcc acatagctcc agcttcgttc ttcacgattt
     1261 tgttgacagg gcagcccatg ttgatatcga cgatatcggt cttggtgttt tcttggatga
     1321 attctgctgc gcgtgctagg ctgtcttcat cgctaccaaa aagttggata gagacagggt
     1381 tttcgccctc atcgatatga agcatgtgca gggttttttc gttgttgtat tggattccct
     1441 tgtcagagac catttccatt acaacgagtc cagctccgag ctcttttgcg atggtacgaa
     1501 aggctgagtt ggtcacgcca gccataggcg ctaaaacggt acgattggga atctcaatat
     1561 tgccaatcat aaaaggtgta ttaagatttg tcacgaatga gttcctccag gtccttttca
     1621 tcaaagttgt aagtagtttg gcagaattga caagtgattt ctgccccgtg gtcttcctct
     1681 ttcatttcct gtaagtctga gcttggaagg ctggcaagag cgttcataaa gcgttcatgg
     1741 ctacagtcac attggaaacg gatttcttct tcagaaagac gcttgtaggc ttcgtccccg
     1801 tagatagcct tgaggagggc ttcgatatgg tcgtcgcttt cgagaagagt agagatagct
     1861 ggcatttctt ggatgcgttt ttcaaagcga gcaatctctt ctttcttggc tcctggcaag
     1921 acttgaacta ggaaaccacc tgcaaccttg accttgtctt cctcgtccaa aaggacattg
     1981 aggccgaccg ctgaaggcgt ttgttggctt tcagtaaggt aaaaggcaag gtcttcaccg
     2041 atttctccag agatgagggg agttatagag ttgtaaggat ttccagtacc gtagtctgtg
     2101 ataacgagga attgaccatt tccaacaaaa ggtccgacta ggacttcacc agtcgcagtc
     2161 tttttgatgt caacaccagg attttgaaca tagcctttga cgttcccctt ggtatcagcg
     2221 acggtgataa tagcacctag agagctagat cccaacacct taactgtaag tttggtattt
     2281 cctttttcat tggctgcgag aatctggctg gcgataagag ttcgaccaag cgctacagtt
     2341 gagctagctt gggtttgatg tttttcttga gcagtgcgga cggtttcagt gctatcaagg
     2401 acaaaagcac gaaaggctcc gctttctgat atagttttaa taattttatc catagctact
     2461 attttagcat aaaaatgccc aaagggggag ccgtgtgttt actgattttc aggataatgg
     2521 accaggaaat cagcatgaaa ataaaaagag aaacagatta tttcagcatt tgtaagattt
     2581 atgctatgct taaggtagaa aatgaaaggg gtaacaaatg tatttaggag atttgatgga
     2641 gaaagccgag tgtggtcaat tttcaatcct ttcctttcta ttacaagagt ctcagacgac
     2701 cgtcaaggct gtaatggaag aaacaggatt ttcaaaagca accctaacca aatatgtcac
     2761 cctgctcaat gacaaggctt tggatagtgg cttagagctg gctattcact cagaagatga
     2821 aaatctgcgt ctgtctatcg gtgcagctac caaggggaga gatattcgga acttgttttt
     2881 ggatagtgct gttaaatacc agattttggt ttatcttctc taccaccaac agtttttagc
     2941 ccatcagctg gctcaagaat tggtgattag cgaggctacg cttggtcgtc acttggctgg
     3001 tttaaatcag attttgtcag aatttgattt atccatccaa aatggacgtt ggcgaggtcc
     3061 agagcatcag attcgctatt tctatttctg tcttttccga aaggtctggt cgagtcagga
     3121 atgggaaggt cacatgcaga aaccagagag aaaacaggag attgccaatt tagaggaaat
     3181 ctgcggtgca agtttgtctg ccgggcagaa attggacttg gttctctggg ctcacatcag
     3241 tcaacaacgt cttcgggtca atgcttgtca gtttcaagtc atagaagaga aaatgcgagg
     3301 gtattttgac aatatctttt atcttcgttt gctgagaaag gttccgtcct tttttgctgg
     3361 gcaacatatt ccactaggag ttgaggatgg tgagatgatg atattcttct cttttctcct
     3421 atctcatcgc attcttcctc ttcatactat ggagtatatt cttggttttg gagggcagtt
     3481 ggtagattta ctgacgcaat tgattcaaga aatgaagaag gaggaactat tgggggatta
     3541 tacagaagac catgtcacct atgaactcag tcagctttgt gctcaagtct atctctataa
     3601 gggctatatt ttacaggatc gttacaagta ccagttagag aatcgtcatc catatttact
     3661 gatggaacat gattttaaag agacagcaga ggagattttt catgctctac ctgcttttca
     3721 acaggggaca gatttagata agaagattct ctgggaatgg ctccagttaa tcgaatatat
     3781 ggctgaaaac ggtggtcagc atatgcggat tggtctggat ttgacatctg gttttcttgt
     3841 cttttcaagg atggcagcca ttttgaaacg gtatttggaa tacaatcgtt ttattaccat
     3901 tgaagcttat gaccctagtc ggcattatga tttgctggtt accaataacc cgattcataa
     3961 gaaggaacag acaccagtct attatttaaa aaatgacttg gatatggagg atttggtagc
     4021 gattcgccag ttattattca cttaaaaggc ttggttaatc caggtctttt ttgtgaaatt
     4081 cacacaatct cctcacattt ttttaaaaat taaaaaaagt tgataaacaa gaaagcgctt
     4141 tattttgtat actagtaagt gtaaagagga aacacctcaa gatctttatc aggaggacag
     4201 tacatgtcac aagaaaaata catcatggcc attgaccagg gaactacaag ttctcgtgcc
     4261 atcattttca acaaaaaagg ggaaaaggtt agctcgagtc aaaaagagtt tacccagatt
     4321 ttccctcaag caggttgggt tgagcacaat gccaatgaaa tttggaactc tgttcagtca
     4381 gttattgcgg gtgctttcat cgaaagtggt gtcaagccaa atcaaatcga ggcaatcggg
     4441 attaccaacc aacgtgaaac aacggttgtc tgggataaga aaacaggact tcctatctac
     4501 aatgctatcg tttggcagtc acgccagaca gcacctttgg ctgagcaact aaaaagccaa
     4561 ggttatgtgg aaaaattcca tgaaaagact ggtttgatta ttgatgctta cttctctgct
     4621 accaaggttc gttggatttt ggatcatgta gaaggtgctc aagagcgagc agaaaaaggg
     4681 gaattgctct ttggtactat cgatacttgg ttggtttgga aattgactga cggtgcggct
     4741 cacgtgactg actactcaaa tgcagctcgt accatgcttt ataacattaa agaactcaaa
     4801 tgggatgatg agattttgga aatccttaac attccgaagg ctatacttcc agaagttcgt
     4861 tctaactccg aaatctacgg caagacagct ccattccatt tctacggtgg agaggtgcca
     4921 atctcaggta tggctgggga ccaacaagca gccctctttg gacagttggc ttttgagcca
     4981 ggtatggtta agaatactta tggaacaggc tctttcatca tcatgaatac tggggaagag
     5041 atgcagttgt ctgaaaacaa cctcttgaca accattggtt acggaatcaa cggtaaggtt
     5101 tattatgcct tggaaggttc tatcttcatc gcaggaagtg ctattcagtg gcttcgtgac
     5161 ggtcttcgca tggttgaaaa ttcaccagaa tctgaaaaat acgctcgtga ttctcacaac
     5221 aacgatgaag tttatgtcgt tccagccttt acaggtctag gcgctccata ctggaaccaa
     5281 aatgctcgtg gttccgtctt tggtttgact cgtggaacaa gcaaagaaga ctttatcaag
     5341 gcgactttgc aatcgattgc ttatcaagtg cgtgacatca tcgacaccat gcaagtggat
     5401 actcagacca ccattcaagt actgaaggtg gatggtggtg cagccatgaa caacttcctc
     5461 atgcagttcc aggcggatat tttaggcatt gatattgcac gtgctaaaaa cttggaaaca
     5521 acagctctag gagcggcctt cctagcaggt ttgtcagtag ggtactggaa agacttggac
     5581 gagttgaaac tcttgaacga gacaggagaa ctctttgagc catctatgaa cgaatctcgc
     5641 aaggaacaac tctacaaggg ttggaagaag gctgtgaaag caactcaagt ctttgcggaa
     5701 gtagacgact aatactggca gaataaagcg atttatttag aaagtgtgta aatatggaat
     5761 tttcaaagaa aacacgtgaa ttgtcaatta aaaaaatgca ggaacgcacc ctggacctct
     5821 tgattatcgg tggaggaatc acaggagctg gtgtagcctt gcaggcggca gctagcggtc
     5881 ttgagactgg tttgattgaa atgcaagact ttgcagaagg aacatctagt cgttcaacaa
     5941 aattggttca cggaggtctt cgctacctca aacaatttga cgtagaagtg gtctcagata
     6001 cggtttctga acgtgcagtg gttcaacaaa tcgctccaca cattccaaaa tcagatccaa
     6061 tgctcttacc agtttacgat gaagatggag caacctttag cctcttccgt cttaaagtag
     6121 ccatggactt gtacgacctc ttggcaggtg ttagcaacac accaactgcg aacaaggttt
     6181 tgagcaagga tcaagtcttg gaacgccagc caaacttgaa gaaggaaggc ttggtaggag
     6241 gtggagtgta tcttgacttc cgtaacaacg atgcgcgtct cgtgattgaa aacatcaaac
     6301 gtgccaacca agacggtgcc ctcattgcca accacgtgaa ggcagaaggc ttcctttttg
     6361 acgaaagtgg caagattaca ggtgttgtag ctcgtgatct cttgacagac caagtatttg
     6421 aaatcaaggc ccgtctggtt attaatacaa caggtccttg gagtgataaa gtacgtaatt
     6481 tgtctaataa gggaacgcaa ttctcacaaa tgcgcccaac taagggagtt cacttggtag
     6541 tagattcaag caaaatcaag gtttcacagc cagtttactt tgacacaggt ttgggtgacg
     6601 gtcgtatggt ctttgttctc ccacgtgaaa acaagactta ctttggtaca actgatacag
     6661 actacacagg tgatttggag catccaaaag taactcaaga agatgtagat tatctacttg
     6721 gcattgtcaa caaccgcttt ccagaatcca acatcaccat tgatgatatc gaaagcagct
     6781 gggcaggtct tcgtccattg attgcaggga acagtgcctc tgactataat ggtggaaata
     6841 acggtaccat cagtgatgaa agctttgaca acttgattgc gactgttgaa tcttatctct
     6901 ccaaagaaaa aacacgtgaa gatgttgagt ctgctgtcag caagcttgaa agtagcacat
     6961 ctgagaaata tttggatcca tctgcagttt ctcgtgggtc tagcttggac cgtgatgaca
     7021 atggtctttt gactcttgct ggcggtaaaa tcacagacta ccgtaagatg gctgaaggag
     7081 ctatggagcg cgtggttgac atcctcaaag cagaatttga ccgtagcttt aaattgatca
     7141 attctaaaac ttaccctgtt tcaggtggag aattgaaccc agcaaatgtg gattcagaaa
     7201 tcgaagcctt tgcgcaactt ggagtatcac gtggtttgga tagcaaggaa gctcactatc
     7261 tggcaaatct ttacggttca aatgcaccga aagtctttgc acttgctcac agcttggaac
     7321 aagcgccagg actcagcttg gcagatactt tgtcccttca ctatgcaatg cgcaacgagt
     7381 tggctcttag cccagttgac ttccttcttc gtcgtaccaa ccatatgctc tttatgcgtg
     7441 atagcttgga tagcatcgtt gagccagttt tggatgaaat gggacgattc tatgactgga
     7501 cagaagaaga aaaagcaact taccgtgctg atgtcgaagc agctctcgct aacaacgatt
     7561 tagcagaatt aaaaaattaa gaaaaaataa aagaggtgga gggcagcatt ccttgtcgct
     7621 cgtcccttct ttttaatgga gacagaaaga tgatgaatga attatttgga gaatttctag
     7681 ggactttaat cctgattctt ctaggaaatg gtgttgttgc aggtgtggtt cttcctaaaa
     7741 ccaagagcaa tagctcaggt tggattgtga ttactatggg ttgggggatt gcagttgcgg
     7801 ttgcagtatt tgtatctggc aagctcagtc cagctcattt aaatccagct gtgacaattg
     7861 gtgtagcttt aaaaggtgac ttgccttggg cttccgtttt gccttatatc ttagcccagt
     7921 tcgcaggggc tatgctgggt cagattttgg tttggttgca attcaaacct cactatgagg
     7981 cagaagaaaa tgcaggcaat atcctggcaa ccttcagtac tggaccagcc atcaaggata
     8041 ctgtatcaaa cttgattagc gaaatccttg gaacctttgt tttggtgttg acaatctttg
     8101 ctttgggtct ttacgatttt caggcaggta tcggaacctt tgcagtgggt accttgattg
     8161 tcggtatcgg tctatcgcta ggtgggacaa caggttatgc cttgaaccca gctcgtgacc
     8221 ttggacctcg tatcatgcac agcatcttgc caattccaaa caagggagac ggagactggt
     8281 cttacgcttg gattcctgtt gtaggccctg ttatcggagc agccttggca gtgcttgtat
     8341 tctcactttt ctagtttata ctcttcgaaa atcaaattca aaccacgtca gcgtcgcctt
     8401 accgtactca agtacagctt gcggctatct tcctagtttg ctctttgatt ttcattgagt
     8461 attagaaaac aattatgttg atagagcttg ggcaagagcc caatttcagc aaaaaatgaa
     8521 gtaaatcttc tcataataaa acgcatcata tcaagcacga aaattccacg aggtcaacta
     8581 cagtcagaaa gctgaacaac aagccaaaac gcccaaaaaa ggcggcaaaa agcaagcacc
     8641 tgcaagcaac gtgccgaaat ggtcaaatcc tgattatgtc aacgaattag acccaaaaat
     8701 cgttgatatg ctagtagaat ttcacaagtc acaaggcact ttggaaactc ccgaggcgca
     8761 agcagaaatc gcccaaaaac gtgaagaaat cgagcaaagg agagctgagc ttgaggataa
     8821 aaaacaagag cttttgaacc gcttgaacaa atagagtttc gcaagtatta tgcttacaaa
     8881 ttacttgagc aattaactaa aatataaacc ctgcctttat atctaggcag ggtttatatt
     8941 ttagaaattc acgtaggttg ttacggtttt tacataccca gtatagtttg agtttctata
     9001 gtattcagtg ataaacttcc attttctttg aacaacatgg atataagtac ttgttatgta
     9061 gtatggatat gggctttgtg aatccaagta agactgataa gcttgtatac caaaatatgc
     9121 tccaccaatt attgcacccc atggaccccc caataaagca cctatcctac caatcatata
     9181 actgattcca gcaccagtca tgaagttagc gaatgtgtta gcttgtttat tcccatgtat
     9241 tgtgttgacg taattccaaa cattaggatc gtatgatcta aaagatatat ttaggtcgat
     9301 ttcattcttt tgataagcca tataaaatgc cccattgata tagacgccgt cagcacgtcg
     9361 ttcaatagtg tctacacttc catctggatt gacaacctca agaacttcat cgcttaaaat
     9421 atttacttgc gtatctccga accgcactga tgagccattc tcaaactgag cctcaccaga
     9481 tctttagagt ttgccgataa gctatcatca gcaaaaacaa caagcgacgg ggaaatgcta
     9541 gacatacaga aaacagacat aactagcaaa cacatgcatt taaacatctt agacataacg
     9601 gaaactcctt tgtatttttg atttttttca acttttatta tacaataaaa ccaaataaaa
     9661 agaaagcggt aacaatatgc ttaatgcgaa aattttttat atatttttat gtttgatcgt
     9721 tatcgaaact acaggcttgt tgttgttgaa aagaggtctc gaaatgggtt atttagacac
     9781 agaagctatt atcctcgcag ttttttcatt tgctttttac aacctatgtt cattcgcttg
     9841 ggtctgctct acaataaaaa ataaatagac gtattttcaa aaaaaaaaaa atgcatattt
     9901 atcttagcaa aacgacgatt taaatcgtcg tttttttgta gtacgacggg catgtcgtat
     9961 atctgaggtg taagtcctcg gtgggcacct gctaccggtg aacccaatag cgattcccaa
    10021 gcctgactat cgtgaggtag cagggagagg aagggatagc gaaatcgtgg ctctacgaac
    10081 aggaacgtga tagtaaggcg tatatagcgg ataaggaggc ttcaaactct aaagtccaaa
    10141 aaggtagtcg taacctatat gtgtaaatca cgagagtaat tgaattcgga ctaaggtttg
    10201 tgtgaaaaag ataaatcttt ctagagtcta aagactctgc gtcagatttc ctattttcac
    10261 tgtaaccttt taacgtcctc atatcttgta taaacgagga aagatgtacg acttatcccg
    10321 tgaggtttca tgagcgctga aagcgtagta acaacgaatc atgagaagtc agccgagccc
    10381 atagtagtga ggaaacttct gtagtggaag tggagcgaag gggtgaatac tcaaacagtc
    10441 tggggagaga ctgtttgagg tctgtcgcta gaaagagaaa acgacagatc gaagtaatcc
    10501 tacttcactt gtgtctgtaa aatgagtggt ctgatagaac tggactttga cacgtaatga
    10561 ctagatgaag gttcaccaat ataagatgtc cctcaggcac caaaacaaga aaggaatacg
    10621 cacatgtcaa aactgctaga taagatatta tcacgcgaaa atatgctgga agcctacaat
    10681 caagtaaaat ccaataaagg ctcagctggg attgatggaa tgactatcga agagatggat
    10741 aattatctca gacaaaactg gcgcttgact aaggaactga taaaacagag aaaatataag
    10801 cctcaaccag ttcttaaagt tgagatacct aaaccagacg gaggcatccg tcaactagga
    10861 attccaacag ttatggatag aatgattcaa caggccattg tccaagtcat gagccccatt
    10921 tgtgaacccc atttctcaga tacgagttat ggtttcagac caaataggtc atgtgaaaaa
    10981 gccatcatga agctcttaga atacttaaat gacggctatg agtggatagt ggatatagac
    11041 ctagagaaat ttttcgatac agttcctcaa gatagattga tgtccttagt acataacatt
    11101 atcgaagacg gagatacgga atccttgatt cgtaagtatc ttcattcagg tgttatcatt
    11161 aatggtcaac gttataaaac actagttggt acaccacagg gaggaaattt atctcctctc
    11221 ttatccaata tcatgcttaa tgaattggac aaggaattag aaaagagggg acttcgattt
    11281 gtgcgctacg cagatgattg tgtgattacg gtcggaagcg aggcagcctc taagcgtgtg
    11341 atgtattcag tcagtcgttt tattgagaaa cggctaggtt tgaaagtaaa catgaccaag
    11401 actaagatta ccagaccaag agagttgaaa tatctaggtt ttgggttctg gaaatcatca
    11461 gatggttgga aaagccgtcc acatcaagat agtgttcgga gatttaagtt taaattgaag
    11521 aaactaacac agaggaaatg gagtatagac ctaacaagac gtattgagca actgaatttg
    11581 tctattcgag gatggataaa ctatttctca ttgggaaata tgaaaagtat agtcgccagc
    11641 atagatgagc gcttgcgtac tcgcctacga gtgattatct ggaagcaatg gaagaagaaa
    11701 tcgagacgat tatggggatt gcttaagtta gg
//
LOCUS       DAVHSL010000061        11616 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000061 DAVHSL010000000
VERSION     DAVHSL010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.063"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVR39_001845"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVR39_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6031259.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /locus_tag="VVR39_001846"
     CDS             complement(2499..3368)
                     /locus_tag="VVR39_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6031260.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3591..4112)
                     /locus_tag="VVR39_001847"
     CDS             complement(3591..4112)
                     /locus_tag="VVR39_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6031261.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4070..5149)
                     /locus_tag="VVR39_001848"
     CDS             complement(4070..5149)
                     /locus_tag="VVR39_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU6031262.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVIEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVRYVDEQGRLLSLKNNTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPITATVTANYYKEGRQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5260..5514)
                     /locus_tag="VVR39_001849"
     CDS             complement(5260..5514)
                     /locus_tag="VVR39_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031263.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5872..6405)
                     /locus_tag="VVR39_001850"
     CDS             complement(5872..6405)
                     /locus_tag="VVR39_001850"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6031264.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6392..6607)
                     /locus_tag="VVR39_001851"
     CDS             complement(6392..6607)
                     /locus_tag="VVR39_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031265.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6574..6717)
                     /locus_tag="VVR39_001852"
     CDS             complement(6574..6717)
                     /locus_tag="VVR39_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU6031266.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            6951..8669
                     /locus_tag="VVR39_001853"
     CDS             6951..8669
                     /locus_tag="VVR39_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU6031267.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVEIEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8780..9127
                     /locus_tag="VVR39_001854"
     CDS             8780..9127
                     /locus_tag="VVR39_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6031268.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9394..10227)
                     /locus_tag="VVR39_001855"
     CDS             complement(9394..10227)
                     /locus_tag="VVR39_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6031269.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSSYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDITLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     G"
     gene            complement(10240..10869)
                     /locus_tag="VVR39_001856"
     CDS             complement(10240..10869)
                     /locus_tag="VVR39_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6031270.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(10879..11520)
                     /locus_tag="VVR39_001857"
     CDS             complement(10879..11520)
                     /locus_tag="VVR39_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6031271.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
BASE COUNT         3421 a         2441 c         2104 g         3650 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggagga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttggtttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgt acttgtaagc gtttttattc ttcacgaaag acctcattct caaaaccagg
     3541 aaaaagccca catctatgag cttttcctgg ttcctagatt ctaaaatcta ttatttttca
     3601 tcttcttttt tcttgaagaa tcctaatcct agaccagcta acaaggtcat gataccagca
     3661 ctagccaagg tagcattagc ttctgtacct gtgtttggca attcctctct cttacctgtc
     3721 tcataagtcg gaacttctgg gtctggattc actggagttt cagtttttgg agtacctggt
     3781 tctggagttg gtttatctgg tgttgataaa cggtcatacc ttaccgttat ttctttatca
     3841 ctagagtctg acgtaacttc ttgtgattca actgttggaa tatctggatc tttgtacttg
     3901 tcaatcttac cagatataac ctcgtcccag tttcctgttg tccattcacc gtaggttaca
     3961 actcccgtga ccttgttctc agtttttgta cggcttaagg ttacaggttg aacaacatct
     4021 tcttttacat tttggttcgt aactttatca acgtaatgaa tgatacgcgt tatagtcttc
     4081 gtctcagtag aggttgctgt tttgggaacc actgtttcct caacattctc acggtagtaa
     4141 tagtcaactg ttgcaccgtc ttctggtacg catttgcagg agttgctacc aaggtgtatg
     4201 ttgttttcct tgtgataact cggtcttctt tgtcctcagt tgttgttttc ccttcaatag
     4261 tttttgattc tgtggtatac tcagaaccta tcgctaaatc agcttttata acagactctg
     4321 ccaacttctc ttgcctacct tctttatagt aattggctgt tactgtagca gtgattggcg
     4381 cttcgctttc tctataaact aaggtcactg ttctaccttc gcttacaata ttcccagtta
     4441 aacttgcaga atttgtatct gcttctttaa aagtataata ttttccgtca gtagtagtca
     4501 tgctactgag ttttttatct gtgacattat agctggtacc aatcagttgt tttttattgg
     4561 taatgtaggt tccgtcactt tctttttctc caattccagt attatttttc aatgatagca
     4621 aacgcccttg ttcatcaaca tagcgaactt tcacattttc tgagattagt tctgccaatt
     4681 ctgaggtttt tttctttttc tcttcttcgg gaatatttag ttttggaatg attttttcaa
     4741 taacggttcg tgatggttcc acagtatctt ggatgactga aaagtcagct agaattggga
     4801 gattatactg aacacggtga ctttgagtgt ttactcctac tctttcatta ttctctgaaa
     4861 atacttgtac ggtataagaa acaacatctt ttcctaatag aacatcccca gtagagaaat
     4921 agccgccttt tcctagtttg ctatctccag agcccacttc tttcctaatc ttatcagata
     4981 gttttttacc agtcagtaca ttcgttcgca caatcccttt gtctacccct acaaagtggg
     5041 agaatttttt gaactcttca gaaccagatc tagcccaacc attattaagg gcatttgctt
     5101 ttgtatttgt attctctctc aaaggtttgg cgattagaat tatattcatc ggcgcttaga
     5161 gttgctgcta tatctgactc ttgaatacca acttccttac taccatttct agcggcagta
     5221 tatgtgtatt tatctgtttc tacttctagc tgattatcct taacatgata ggtaattttc
     5281 tcctggtata agagtcttca gtagtttata tgctctgtca tcatctttag ctttagaagc
     5341 agctgagttt agccaagttg gggtattagg agtatcttta tcagcctgtt tcaagacatt
     5401 attcaagtca tttgctagcc tattggttat cctcactgtg aaagttttct tccagtctga
     5461 accactttta ttagacttag atatgctcat gaaatcctgg tcaacattca acacaatatc
     5521 gccttgtttt ttagcatctt ccgttgcttc tgcttcaaat tgatcatgga gtttttgttg
     5581 ctctggtgta tagttttttt atttacacga tttaatgtac tattttttat tttagtatta
     5641 agaactccat taatacgatt tttaaattct gcttcaaaaa atcccttaat ttgttggtgc
     5701 gcaagttcaa cattcaaacc tttcttatac aagtcttcat tctgatacaa gtcttcattc
     5761 tgaacgattt cggctacacg gtgaatggtt tgattgtata ccgtcttctc ttaaccagca
     5821 gtatccttag ttttaatgac tactcgatag gttcctttag aaccgttata gtcatctagt
     5881 tttaaaaaag cattccaaac attcaaaaat agttggaact tcccttaata aatccgtcac
     5941 tttctttttc aagatagccc aagcttgctc aataggattc aaatccggtg aataaggtgg
     6001 tagaggtaag aaaaagtgtt tatcttggat gcagagttca tccaaaatgt tcttgggatg
     6061 aaaactagca ttgcccatga caataacatg aggtgtcttc aaagcaggta ggagttgcgt
     6121 tttgaaccac tccacaaaga aatcgcttgt catgcttttc ttgtaaatca tgggagctat
     6181 aaactctccg tctacttgtc ctgcaacaat tgaagttcgc tcaaaacgac gtccgctaat
     6241 cttttcatag actttctccc ctctaggagc ccctgcataa ggacgataga ggtagcggtc
     6301 gattcctgtt tcgtcaatat atacgattgg taaatctttt aggttatcca aaatatcaag
     6361 aaactcagcg actttctctg gctcttgttc cttaaagctc gtcatctttt tttaaagtga
     6421 ccttaatctg ctttaaagct gcccatactg aaggaacagc acaatcaaaa tgtgccgcaa
     6481 tttcccgtaa aaaagcatct ggatgagcct ctacaaaggc tttcaattcc tctaaaggaa
     6541 tctttcggtt tttgacgact cgctttttcc tctctatgtg tccttgttca cgtctttctt
     6601 ttcccacgtg aagagagttc tgacgccaac accaaaaaac ttggctgcct cgacatgact
     6661 gtgcccctct ttgatggaat ctaatgctcg ctgtttaaaa tcagtactat atgccatagc
     6721 tttattataa catgtatttt ataaactaag ctactatatc aatgttttgt tatgagaaga
     6781 cttacttttt ttactgaaat tgaatttttc ctagcctcaa catcatataa ccccaaaatt
     6841 caatctgacc tggtttgaag agatgttcga agcagataag gttttactaa aactaaaaaa
     6901 aatgatataa tcaaactgat taaatgtttt aaaactaaag gagaatttga atgtcttacc
     6961 aagaaaatta ccagaaatgg gttgattttg tggagcttcc tgactacctt cgtcaagatt
     7021 tggaaaatat ggacgaaaaa actaaggaag atgccttcta tacaaatctt gaatttggta
     7081 ctgcaggtat gcgtggcttg gttggtgctg gtacaaaccg tatcaacatc tacgttgttc
     7141 gccaagctac tgaaggattg gctcgtttga ttgagtcaaa aggtggaaac gagaaagaac
     7201 gcggtgtagc aattgcctac gatagccgtc acttctcacc tgagtttgcc tttgaatctg
     7261 cggcagttct tgctaaacac ggcatcaaat cttacgtatt tgaaagcctt cgtccgactc
     7321 cagaactatc atttgcagtt cgtcatctca actgtttcgc aggtatcatg gtcacagcca
     7381 gccacaaccc tgctccattt aacggttaca aggtttacgg tgaagacggt ggacaaatgc
     7441 ctccacacga tgcggacgct ttgactactt atatccgtgc aatcgaaaac ccatttgcag
     7501 ttgaagttgc tgatgtggaa attgaaaaag cttctggctt gattgaagtt atcggcgaag
     7561 ctgttgacat agaatacctt aaagaggtta aggacataaa catcaaccca gccttgattg
     7621 aagaatttgg taaagacatg aagattgtct acacaccact tcatggtact ggtgaaatgt
     7681 tggctcgtcg tgctcttgcc caagcaggat ttgactctgt tcaagttgtt gaagcgcaag
     7741 caactgctga cccagacttc tcaactgtaa catctccaaa cccagaaagc caagcagcct
     7801 ttgcccttgc tgaagaactt ggtcgtcaag ttggtgcaga tgttcttgtc gcaactgacc
     7861 cagacgctga ccgtgttggt gttgaagttc ttcaaaaaga tggtagctac ctcaaccttt
     7921 caggtaacca aatcggtgct atcatggcta aatacatctt ggaagctcac aaaaacgctg
     7981 gaactcttcc tgaaaatgcc gctctctgca aatctatcgt ttcaactgac ttggtaacga
     8041 agattgctga aagctacggc gcaactatgt tcaacgtctt gacaggtttc aaatttatcg
     8101 ctgaaaaaat ccaagaattc gaagaaaaac acaaccacac ttacatgatg ggatttgaag
     8161 aaagcttcgg ttacttgatt aaaccatttg tacgtgataa agatgccatc caagccgttc
     8221 ttgtcgttgc tgaacttgct gcctactacc gttctcgtgg tttgacactt gctgacggta
     8281 tcgaagaaat ctataaagaa tatggctact acgcagaaaa aacaatctct gttactcttt
     8341 caggtgtcga tggtgctgaa caaatcaaag cgattatggc taaattccgc aacaatgctc
     8401 caacagaatg gaacgcaaca gctatcactg tcgtagaaga cttcaaggca caaactgcta
     8461 ctgttgctga cggtactgtt acaaacttga caactcctcc aagtgatgtg ttgaaataca
     8521 cacttgctga cggttcatgg attgccgttc gcccttcagg tacagaacca aaaatcaagt
     8581 tctacattgc agttgtaggg gaaaccaacg aagaatcaca agctaagatt gctaacatcg
     8641 aagcagaaat caatgcattt gtaaaataaa gacctataaa agatgagacc aaccaacctc
     8701 atcttttttc gtatcaaatc taagcaattt tagaaacttt atggcatact agacttatca
     8761 atgaaagcga ggtaatctca tggaacaatt tttagataac atcaaagacc ttgaagtcac
     8821 tacagttgtg cgtgcgcaag aagctcttga taaaaaagaa actgcaacct tctttatcgg
     8881 tcgcaaaact tgcccttact gccgtaaatt tgcaggtaca ttgtcaggtg tcgtagctga
     8941 aaccaaagct cacatttact tcatcaatag tgaagaacca agccaactca atgatttgca
     9001 agcattccgc tcacgctatg gaatcccaac tgtaccaggt tttgttcata ttacagatgg
     9061 acaaatcaac gtccgttgcg actcttcaat gtcagcacaa gaaatcaaag atttcgcagg
     9121 attgtaaaaa atcagctaac aagtcttaaa atcacaaaaa cgcataatgt aaggtgcaaa
     9181 aaccttgata ttatgcgttt tattgttcct aaaacagtta catcagtatt tcattacaga
     9241 acattttaat tttggaagtc aaatcaattt ttaacaatgt tttagaaatc acagtgggct
     9301 attccatatt caatcgctat tatcgttttc ctagattaca aaaaaactac gttttgctaa
     9361 tcaaaacgca gtttcagcca ctattttatc ttactatcct tcttttactt ctttggttgc
     9421 tacatcttct ccaaaccatt tttggctgat ttcttggaac ttgccgtcct tgtaaagact
     9481 agaaaaagct tcatttatct tcttaaccaa ggttatatct tccttacggg ctccaaccgc
     9541 aaaagcttct gtttctagtc caactgtaaa gacattataa tcgtttaaaa caccttctgc
     9601 ttctaaataa tagtttgcat agacacggtc aatcaataga ccatcaattc gatcgttttt
     9661 caaatcaatc aaggcttcat taaaggtttg gtattgattc gcttccttat tagcgacaat
     9721 attcttcaaa atttctggat ttgcttcaaa gtccgcataa ctagatgaac cagcttgagc
     9781 tcctaatgtc tttccagtca tatcctttgc agtcgtgata ccagatgatt tcttcgtaac
     9841 caatacctgc tcattcttca tatatgagtt actgaaagca accttttcac ggcgttcgtc
     9901 tgtagcggaa tagccattcc aaatcagatc aatcgttcct tttgtcaatt cagcttcttt
     9961 caaatcccaa tcaatcggtt gccaatttac cgtgattccg tatttttcaa aaacagctgt
    10021 agctaaatca atatcaaatc ctgcataaga accatctttc tgagcaaatc ccattggaac
    10081 aaaagtacta tcaaatccaa tagtaataga cttgttagac tggtactttg accaattatc
    10141 tccactagtt tcgctagaat ttttcccaca agctactaag aacaaagcag tcatcagact
    10201 gactaataca agcatccatt ttttcatcca tttttcctcc tatttaggtt ctactttcaa
    10261 taatacatct gcgatatttt cagcaaactg caaatcatgg gtaaccacaa tctgggtcat
    10321 cccaagttcc ctattttgca agattagctt ctccacttcc aaacgtaatt ctggatccag
    10381 ggcagaagtt ggttcatcgt agccaatgat ttctgggtca atcatcatag cacgcgccaa
    10441 agccacccgc tgcttttgcc caccagatag tgagaaagga taggcctctg cgtgtcctcc
    10501 tagtcctaac tgttccaaga gtccactcgc cttcttctca gcctcttcct gcttcattcc
    10561 catggtcttc acaggcgata aggtcaaatt gtccagaact gataaatgag ggaacagttg
    10621 aaaatcttgg aatacaaatc ccagtagatt gcgcttctgc aattcatcca gctctaaagg
    10681 ttgtccatta taaaagattt gccctgaatc aatggtttca agacctgcaa gcatacgtaa
    10741 aagagttgtc ttacctccac cagaaggtcc aacgatagcc aggatttgct tttcaggaat
    10801 acttagactg aaattagaca ggatttgttt gtctccaaag actttattga tatttcgtaa
    10861 ttctaacatg gcagcctcct atctataata actatacttc ttctcaactt ttttggaaat
    10921 aattgtcaca atcccaatca aaatcaaata aatggctcct gccaagaaca taggaactag
    10981 actagcatcg cggttagcag ctgttcgact agccaagata aggtctgaaa ttccgagagc
    11041 atagaccaaa gaagtatcct tgaccaaact cataacttca ttaaagacac taggaagaac
    11101 gatcttggtc acttggggca agataatata gcgcactctg tcaaaagggc taaacttcaa
    11161 gaccttggcg gcctcatact gtcctcttgg aatagtgtca attcccccac ggaaaatttc
    11221 tgcaaagtaa gctgcatagt tgagaacaaa ggcaataata gctgcaggaa ggcggtctaa
    11281 acgaatccca atacttggga gcacataata gataaaaatc agttgcaaga gtaagggggt
    11341 tcctcgcata acccagatgt aaatattaat cagataatgg aggggcttcc aatggacttg
    11401 caaggcaaag gcaatcaaaa cgcccaaagg aatcgaaaat agcaagacca gtgcaaagac
    11461 ctgtacagtc gtgctcgcac cattcagtaa actcggtaat atctcaaata aataagacat
    11521 actgcacctc ctaaaagtaa ttgttcctat tatagcatga ataaacaaga ttaccaagta
    11581 tttttgtaaa aagattctac catatacaaa taaaaa
//
LOCUS       DAVHSL010000062        11164 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000062 DAVHSL010000000
VERSION     DAVHSL010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.064"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            23..379
                     /locus_tag="VVR39_001858"
     CDS             23..379
                     /locus_tag="VVR39_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031272.1"
                     /translation="MSGIVGLVGGILLLIGPFVLLGTTVNTAATTLNGGATAGTFSGV
                     ALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGWVGGILAII
                     GGSLFLATLKKFKSEE"
     gene            914..1606
                     /locus_tag="VVR39_001859"
     CDS             914..1606
                     /locus_tag="VVR39_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU6031273.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1659..4070
                     /locus_tag="VVR39_001860"
     CDS             1659..4070
                     /locus_tag="VVR39_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6031274.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQSPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVCFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4320..5021
                     /locus_tag="VVR39_001861"
     CDS             4320..5021
                     /locus_tag="VVR39_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031275.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5023..7731
                     /locus_tag="VVR39_001862"
     CDS             5023..7731
                     /locus_tag="VVR39_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6031276.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7827..8318)
                     /gene="tpx"
                     /locus_tag="VVR39_001863"
     CDS             complement(7827..8318)
                     /gene="tpx"
                     /locus_tag="VVR39_001863"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU6031277.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNMVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8441..9370)
                     /gene="psaA"
                     /locus_tag="VVR39_001864"
     CDS             complement(8441..9370)
                     /gene="psaA"
                     /locus_tag="VVR39_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU6031278.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9402..10250)
                     /locus_tag="VVR39_001865"
     CDS             complement(9402..10250)
                     /locus_tag="VVR39_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6031279.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10247..10969)
                     /locus_tag="VVR39_001866"
     CDS             complement(10247..10969)
                     /locus_tag="VVR39_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6031280.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3275 a         2072 c         2546 g         3271 t
ORIGIN      
        1 gaaattaaaa acacttgctt taattagtgg tatcgtcggt cttgtgggag gaattttact
       61 tcttattggt ccttttgtct tgttgggaac aacggtaaac acagctgcta caactcttaa
      121 tggaggagct actgcaggga ctttttcagg tgttgcctta ctcttgaatg ccttgaagat
      181 tgcaaatctt gttcttggta tcattgctat tgtttactat aaaggagata agcgtgtagg
      241 tgcagctccg tctgtactaa tgattgtttc tggtggagtt agtctcattc cattcttagg
      301 atgggttggg gggattcttg ctattatcgg aggatctcta ttccttgcaa cattgaagaa
      361 attcaaatca gaagaataaa aggtatttta gcatgaaaag aacaaaaaag tttatcggta
      421 taggagtagc tctattatct ctttctcttc tagttgcatg tggaacataa agttcaaaga
      481 atacttcaac aagtaatgat gagaagacag tagcaacatc caatagttca aaagaaacaa
      541 tcactttcga tacaccggtt gtaacagacg atgcgattga atcaatacgc acttatgcag
      601 attatataga tctttataaa aatatttttg atgattattt tactaaagct gaggaaggtt
      661 tcaaaggcac agctatggaa aataatgact cgtttactaa actaaaagag tcaactcaaa
      721 aattattcga tgcgcagaaa aaaaggttaa ataatgaaga tagaatagaa acagccaaaa
      781 acaatgtgat tgccaaacat tgtcaaacag tcctttcctt tttggttttg actagctttt
      841 ttgtgaaaaa ttgtgtaaaa tagaatagat aaacgagggg aaacctcgga aaatttaaag
      901 gagaatccat ctaatggtaa aattggtttt tgctcgccac ggtgagtctg aatggaacaa
      961 agctaacctt ttcactggtt gggctgatgt tgatttgtct gaaaaaggta cacaacaagc
     1021 gattgacgct ggtaaattga tcaaagaagc tggtatcgaa tttgaccaag cttacacttc
     1081 agtattgaaa cgtgctatca aaacaactaa cttggctctt gaagcttctg accaattatg
     1141 ggttccagtt gaaaaatcat ggcgcttgaa cgaacgtcac tacggtggtt tgactggtaa
     1201 aaacaaagct gaagctgctg aacaatttgg tgatgagcaa gttcacatct ggcgtcgttc
     1261 atacgatgta ttgcctccaa atatggaccg tgatgatgag cactcagctc acacagaccg
     1321 tcgttatgct tcacttgacg actcagtaat cccagatgct gaaaacttga aagtgacttt
     1381 ggaacgtgct cttccattct gggaagataa aatcgctcca gctcttaaag atggtaaaaa
     1441 cgtattcgta ggagctcacg gtaactcaat ccgtgccctt gtaaaacaca tcaaaggttt
     1501 gtcagatgat gagatcatgg acgtggaaat ccctaacttc ccaccattgg tattcgaatt
     1561 cgatgaaaaa ttgaacgttg tttctgaata ctaccttgga aaataaaaaa ttgtaagcct
     1621 aggattgatt tctaggcttt ttatgttagt atggaagtat gataaggaat aaaaaacaag
     1681 attatgtact ggcctacaag caaccagctt caaccactta catgggttgg gaagaagaag
     1741 ctttaccgat aggtaatggt tctttaggag caaaagtatt tggccttata ggggctgaac
     1801 ggattcaatt taatgaaaaa agtctctggt ctggaggtcc acttcctgat agttcagatt
     1861 atcagggtgg aaatcttcag gatcagtatg tttttttagc tgagattcgg caggctttgg
     1921 agaagagaga ttacaatctg gctaaggaac tggctgagca gcacctaatt gggccaaaaa
     1981 cgagtcaata tgggacctat ctgtcttttg gggatattca cattgagttc agccagcaag
     2041 gtacgacttt gtctcaggtg acggactatc agagacagtt gaatattagt aaggcacttg
     2101 cgacgacttc ttatgtctat aagggaacgc gatttgaacg tgaagctttt gcgagttttc
     2161 cagatgatct cttggttcaa tgttttacta aggaagggtt ggaaactcta gattttacta
     2221 tagaactatc cttgacctgt gatttggctt ctaatggaaa gtatgagcag gaaaaatctg
     2281 attacaagga gtgtaagttg gatattactg attctcatat cttgatgaag ggaagagtta
     2341 aggataatga tctgcggttt gctagttatc tagcttggga aacggatgga gatattagag
     2401 tttggtcaga tagggttcag atatcaggag ccagttatgc caatctcttc ttggccgcta
     2461 agacggattt tgcccaaagt cctgctagca attatcgcaa gaaactagat ttagagcaac
     2521 aggtgataga cttggtggac acagctaaag aaaagggcta tacccaattg aaatcaaggc
     2581 atatcgagga ctaccaagcc ttattccagc gtgttcaatt ggatttggaa gctgatgttg
     2641 acgcatccac tacagatgat ttgttaaaaa attataagcc acaagaaggg caggctttgg
     2701 aggagctgtt cttccagtat ggacggtatt tattgattag ttcgtccaga gactgcccag
     2761 atgctctacc agctaaccta cagggagtct ggaatgcggt cgacaatcct ccttggaatt
     2821 cggactatca cttaaatgtc aatctgcaga tgaattattg gccagcctat gttaccaatc
     2881 tcctagagac ggtctttcca gtcatcaact atgtagatga tttgcgtgtc tatggtcgtc
     2941 tagcggctgt aaagtatgca ggaatcgtct ctcagaaagg tgaggagaat ggttggttgg
     3001 ttcatactca agcgactccc tttggttgga cggcacctgg ttgggattac tattggggtt
     3061 ggtcaccagc tgccaatgcg tggatgatgc aaaccgttta tgaagcctat tcattttata
     3121 gggaccaaga ctatctcaga gagaaaattt atcccatgtt gagggaaacg gtttgttttt
     3181 ggaatgcctt tttacataag gatcagcagg cgcagcgttg ggtgtcttct ccgtcttatt
     3241 ccccagaaca tgggccgatt tcgattggca atacttatga ccaatctctg atttggcagt
     3301 tatttcatga ttttattcag gctgctcagg aattgggact ggatgaggac ttgttgactg
     3361 aggttaagga gaagtctgat ttactaaatc ctttgcaaat cactcaatct ggtcgaatca
     3421 gggagtggta tgaggaggaa gagcagtatt ttcaaaatga gaaagtggag gcccagcatc
     3481 ggcatgcttc ccatctagtg ggactctatc ctggcaatct ctttagctac aagggacaag
     3541 agtatattga agcggcgcgt gctagcctca atgatcgtgg agatggcggc acaggctggt
     3601 ccaaggctaa taagatcaat ctctgggcgc gtttgggaga tggcaatcga gcccataaat
     3661 tattggcaga gcagttaaag acatccacct tgccaaatct ttggtgtagc catcctcctt
     3721 ttcagataga tggtaatttt ggtgctacta gtggcatggc agaaatgtta ctccagtctc
     3781 atgcagctta tctggtacct ctagctgccc tacctgatgc ttggtcaaca ggttctgttt
     3841 caggcttaat ggcacgtgga cattttgaag tgagcatgag ctgggaagat aaaaaactct
     3901 tacagttgac cattttatca aggagtggag gagatttgcg agtttcttat ccagatattg
     3961 agaagagtgt gattaaaatg aatcaagaaa aaataaaagc gaaatgcatg gggaaagatt
     4021 gtatttcggt ggcaacagca gaaggtgatc ttgttcaatt ttatttttaa gaagatgtta
     4081 taaggcagta atttgaaact tccttttaat aaggatttga gaatataggc agtttccaac
     4141 tagttgaaaa agcgttataa tgataatagg aagtaatact caatgaaaat caaagagcac
     4201 aaactaggaa gctagccgca ggttgctcaa aacagtgttt tgaggttgta gatggaagct
     4261 gacgtggttt gaagagagat tttcgaggag tataatttgt ttgatagagg gtgggtctga
     4321 tggcttatat tgagatgaaa cactgttaca agcgttatca ggttggggac acggagattg
     4381 tggccaatcg tgatgtgaat tttgagattg aaaaggggga gctggttatt atccttggtg
     4441 cttcaggtgc aggcaagtca acagttctta accttcttgg gggaatggat accaatgatg
     4501 aaggggaaat ctggattgat ggtgttaata ttgcggatta tagttcccac cagcgcacca
     4561 attaccgtag aaatgatgtg gggtttgttt ttcagtttta taatctagtt tctaatctga
     4621 cagctaagga aaatgtggaa ctggcttctg aaattgtgac agatgccttg aatcctgatc
     4681 aggtcttgac agatgtaggt ctggctcatc gtctcaataa ctttccagcc cagctttctg
     4741 gaggggagca acagcgagtc tccattgcac gcgcggtagc caaaaatcct aaaattcttc
     4801 tttgtgatga acctactgga gccttggatt atcagacggg caagcaggtt ttgaaaattc
     4861 tccaagatat gtctcgtcaa aagggagcga cggtgatcat cgtgactcat aatggagctt
     4921 tggcgcccat tgctgatcgc gtgattcata tgcacgatgc cagtgtcaag gatgtggtgc
     4981 tcaaccaaca tcctcaggat attgacagtt tggagtacta gcatgatcaa gcgaaaaact
     5041 tattggaagg acttaattca gtccttcaca ggctccaagg ggcgtttttt atccatcttg
     5101 atcctgatga tgttgggatc tctagcctta gtaggcctca aagtaaccag tcccaacatg
     5161 gaggcgacag ctaatgctta tttaacaact gctcaaacct tggatttggc agtcatgtct
     5221 aactatggct tggatcaagc agaccaagaa gaactaaaac agacggaggg cgcagaggtc
     5281 gagtttggct atttgacaga tgtgactatg gataatgggc aggatgccat tcggctgtac
     5341 tccaaaccag agcgaatttc aacctttcag ctaagaaagg gacgacttcc tcagtcagac
     5401 aaggaaatcg ctttggccac tcatttgcaa ggccaataca gcgtgggaca ggagattagt
     5461 tttaaagaaa aagaagaggg tcattcctct ttaaaagacc atacttatac cattactggt
     5521 tttgtggatt cggctgaaat cctctcccag cgagatatgg gctacgcagg aagtggaagt
     5581 gggactctga cagcctatgg ggtgatttta cctagtcagt ttgatcagaa agtctacaat
     5641 atagctcgtt tgaaatatca agatttagca ggtttaaatg ccttttcatc agcttatgaa
     5701 gaaaaatcca agcaacatca ggaagagctt gaacaaactt tatcagataa tggcaaggta
     5761 cgtctgcaac ttttgaaaaa agaaggacaa gagtctctag acaaggggca agagaccctt
     5821 gacaaggctc agactaattt gcaggaaggc aagcgtcgtt tagcagctgc tcaagctcgt
     5881 atacaggctc aagaaagtca actagccttg tttcctcaag ttcagagaga gcaggctagt
     5941 gctcaactta cccaagccaa gcaggaattg ggcaaggaag aggataaact aaagcaagct
     6001 gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac atcagcaagt cttggacgat
     6061 ttggcggagc caaggtatca ggtctataat cgtcagacca tgccaggtgg tcagggctat
     6121 cttatgtata gcaatgcttc atccagtatt cgagcagtgg gcaatatctt tcctgtggta
     6181 ctttatgccg tagcagccat ggtgaccttt acgaccatga ctcgctttgt agacgaagag
     6241 cgaactcatg cagggatttt taaggccttg ggttaccgta gtaaggatat tatcgccaag
     6301 tttctccttt atggactagt agctgggact gtcggaacgg ctctaggtag tatacttggt
     6361 cattatttgc tagccagtgt aatttcaagt gtcattacaa aaggcatggt ggtgggagaa
     6421 acccagattc agttctattg gacctatagc ttactagctc ttgtcttgag ctggttggcg
     6481 agtgtgttac cagcctatct ggtggcttgg agggaacttc atgccgaagc agcccagctt
     6541 ctacttccta aacctcctgt caaaggagct aaaatcttat tggagcgtat cggttttatc
     6601 tggcgtcgtc tcagttttac tcataaggta acagcccgca acatctttcg ttataagcag
     6661 agaatgttga tgacaatctt tggtgtggca ggttctgtag ctctgctctt tgcaggtttg
     6721 ggaatccaat cttctgtagc aggagttccg tctaaacagt ttcaacaaat ccaacagtat
     6781 cagatgcttg tctctgaaaa tcctagtgcg accaatcagg acaaggtaga gctagcagaa
     6841 gtgttgaaag ggcaggagat actagcctac cagaaaatct attctaaaac gctagacaag
     6901 gatttcaaag gcaaggctgg tcttcaaaac attactctta tgatgataga gaaggaagat
     6961 ttgactccct ttatccatct tcaacatcat cagcaggagc tgacattaaa agatggcatc
     7021 gttattacag ctaaactcgc ccagctggca ggtgtcaagg ttgggcagac tttagaaatt
     7081 gaaggtaagg aactaaaggt cgctgctatt actgagaact acgttggtca ctttatttat
     7141 atgagtcagg ctagctatga gcaactttac ggacagctac cccaagccaa cacttatctg
     7201 gtctcattaa gggataccag tgcaactagt atcgaaagtc aggcgggctt gcttatgaat
     7261 caatctgcgg tgtccagcgt tgtccaaaat gcttcagcca ttcgactctt cgactctgtc
     7321 gctagctcac tcaatcagac catgaccatc ttggtcatcg tatcggttct attagctatt
     7381 gtcatccttt acaatctgac caatatcaac gtagctgaga gaatccgtga actctccact
     7441 accaaggttc ttggttttca taataatgaa gtcaccctct acatttaccg tgagacgatt
     7501 gtgctatccc ttgtgggaat cgtacttggt ctggtagctg gtttctattt acaccaattt
     7561 ttgattcaaa tgatttcgcc tgcgactatt ctcttttatc cgcaggtagg ctgggaagtc
     7621 tatgtaatcc cagtggcagc agtaagcatc attttgacct tgcttggttt cttcgtcaat
     7681 tattatctga gaaaggttga tatgttagaa gccctgaaat ctgtagagta aggtagttat
     7741 ttttagctga ttgaacttct atttactaat attcaaaaat cctccgtttc aaagagcagg
     7801 gaactctttg tgacagagga ttttttctat agggctttag cagctgcaat tgcggcttcg
     7861 aagtttggct cagaattgat attatccacg tattcaacgt agcgaatcgt attgtcagta
     7921 tcgaggacaa agactgcgcg tgctaatagg tgccattcgt tgatcaagag ggcataatcg
     7981 tgcccgaaag aatggtcaaa gtagtctgaa agcataatgg cattgtcaag gccttcagca
     8041 ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa cagtcaatac gaccatgttg
     8101 tccagtccag ccaattcttc attaaaacga cgtgtttgag ttgagcagat gcctgtatcg
     8161 atagaaggaa cgacactcaa gacttttttc ttgccatcaa aatcagccag agatttttta
     8221 gaaagatctg ttgtagtaag agaaaaatca agcgccttgt cgccgacttg tagttgttta
     8281 cctgtaaagc tcacaggatt tccgagaaaa gttaccatag gatactccaa tcttttttct
     8341 tccattgtat ctgaaacagt cagaattttc caatgatttg accggaaatg tgggcataga
     8401 aaaaacgcca gctcacatga gaatgacgtt tttcagaggc ttattttgcc aatccttcag
     8461 caatcttgtc aaggttgtat ttcatcatgc tgtagtagct gtcgccttct ttaccttgtt
     8521 ctgcgataga gtcagtaaag atttgtgcgt agattgggat gtttgtgtct tgagaaacag
     8581 ttttcattgg acggtcatcc acacttgatt ctacaaagag tgatggaact tttgtttggc
     8641 gaagtttttc aaccaaggtc ttgatttgtt caggagttcc ttcttcttca gtattgattt
     8701 cccagatgta ggcacttggg acaccatagg ctttagagaa gtatttgaat gctccttcgc
     8761 tggttacaat gagtttcttt tcagcaggga ttttattaaa tttatcctta ctttctttat
     8821 caagtttgtc taacttatca gtatattctt tgagattttt ttcatagaat tctttattgt
     8881 tagggtcttt ggcgctcaat tgtttggcga tatttttagc aaaaataata ccgttttcaa
     8941 ggttaagcca agcgtgtggg tcttcttttc ctttttcatt ttgaccttcg aggtagataa
     9001 catcaacgcc gtcgctgact gcgaagtagt ctttgttttc agttttcttg gcattttcta
     9061 ccaattttgt aaaccaagca ttgccacctg tttcaaggtt gataccgtta tagaaaatca
     9121 aatcagcctc agaagttttc ttaacgtctt caggaagtgg ttcgtattcg tgtgggtctt
     9181 gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc agcaatattt ttagtaatat
     9241 cagcgatgat tgagtttgta gcaacaactt ttagtttttg accagaagtt gtatcttttt
     9301 ttccgctagc acatgctaca agaatgattg cagaaagaaa gagaacgagt aatgtaccta
     9361 attttttcat tagatcctcc aatttattag ggctttgccc cttattttaa caaatgttta
     9421 tttttcagtt tcaaatatcg ttgtttggga gcgataaaga agctaatgag aaagaaacta
     9481 gcagctgtaa gcacgatact agaacctgcc gcaacattaa aactatagcc aataaagagt
     9541 cccaaaactg aagcagtagc tccgaaggtt gaggaaagga aaatcatact tttcagacta
     9601 ttagcataca gataagcagt tgcagctggg gtaatcagca tggctacaat caggatagtt
     9661 ccgacacttt gcatggctgt cacagacacg agagtcagga gtaccatgag aaggtagtga
     9721 tagaaattga caggcattcc catggcttta gccaagagtt catcaaagga agttatcaag
     9781 agttgcttga agaaaatcca aattaacaag aggatggctg cccccacacc catagtaata
     9841 aacatatccg tatcttggac ggccagaata ttaccaaaaa ggatatggaa aaggtcagtt
     9901 gaacttttag cgacaccaat caagatgata ccgagggcta agaaagaaga aaaggtaatg
     9961 ccgatggcgg tatcgctttt gataatcgag tttcctttga tgtaggtaat gatgatggca
    10021 gctagcaatc caaagacaat ggctccgata aagaagtcaa ggcccaagat gaaggagagg
    10081 gctacacctg gtaagacagc atgtgaaatg gcatctccca tgagtgacat cccgcgtaga
    10141 ataatgaaac atcccacagc tccagctaca atcccgacga caatagctgt tatcaaggca
    10201 ttttgtagga aatggaattt ttgcaatcca tcgataaatt ctgcaatcat aggtcacctc
    10261 cattgaaaaa gagttgatta ccgtaagctt cttttagatt ggtttcggta aaagtttctt
    10321 ttgttggacc aaaggcaatc acttctcgat tgacaagtaa gacttgatcg aagtagtggg
    10381 gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt cccagctttt ttcaaatctc
    10441 tcagcgtatt catgatgatt tcctcactga cagagtcaat cccagcaaag ggttcatcca
    10501 agaggatata gtcggcttcc tgcaccaaac atctggcaat caagacccgc tggaattgac
    10561 ctccagacag ttgactaatt tgacgttcag cgtagtcagc taggccgacg atttcaaggg
    10621 cctcttgcac tttcttccaa tgtttagcct ttaaacttcg aaagagagga atagagggaa
    10681 atagtcctaa cgagacgcat tccttgacct tgatgggaaa gttgtagtcg atattgattt
    10741 tttgttcgac ataggcaatt cggtgtaagg attttttaac ttccttgtca tcgagaaatg
    10801 cctgaccttg atgtgggata attcccagca taccttttaa tagtgttgat ttcccagcgc
    10861 cgtttggacc aatgatgccg gtaattgttg gtccatggag cactagtgaa atatccttaa
    10921 gtgccaacgt ttctttgtag gagacactga ggttttcgat acgtatcata aacttgtatt
    10981 cctcctgtct cttaatatac attaaaaaaa aaattaagtc aagttaattt ttgaaaaaat
    11041 taaaataata actgaaaaat agattctaaa gataactttc aggataaatt tctaaattat
    11101 aaaacgcata gtatcaagtg taaagaactt ggaattatgc gttttatcat ggaaaggttt
    11161 ttta
//
LOCUS       DAVHSL010000063        11134 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000063 DAVHSL010000000
VERSION     DAVHSL010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.065"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            31..1143
                     /locus_tag="VVR39_001867"
     CDS             31..1143
                     /locus_tag="VVR39_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6031281.1"
                     /translation="MRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFS
                     TRLAQKIGLEHLFTYNLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQA
                     NQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPN
                     HRYNHRLAPQTKQKSQIKVMCNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSH
                     EAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFI
                     YWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGY
                     SFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            1282..1608
                     /locus_tag="VVR39_001868"
     CDS             1282..1608
                     /locus_tag="VVR39_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6031282.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            1595..2188
                     /locus_tag="VVR39_001869"
     CDS             1595..2188
                     /locus_tag="VVR39_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU6031283.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            2181..3092
                     /locus_tag="VVR39_001870"
     CDS             2181..3092
                     /locus_tag="VVR39_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU6031284.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENANLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            3155..4219
                     /locus_tag="VVR39_001871"
     CDS             3155..4219
                     /locus_tag="VVR39_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031285.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAKEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISTLVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(4397..5257)
                     /locus_tag="VVR39_001872"
     CDS             complement(4397..5257)
                     /locus_tag="VVR39_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU6031286.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWLIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(5379..6365)
                     /locus_tag="VVR39_001873"
     CDS             complement(5379..6365)
                     /locus_tag="VVR39_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU6031287.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(6637..8112)
                     /locus_tag="VVR39_001874"
     CDS             complement(6637..8112)
                     /locus_tag="VVR39_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU6031288.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(8322..9245)
                     /locus_tag="VVR39_001875"
     CDS             complement(8322..9245)
                     /locus_tag="VVR39_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6031289.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(9259..10188)
                     /locus_tag="VVR39_001876"
     CDS             complement(9259..10188)
                     /locus_tag="VVR39_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6031290.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(10507..10728)
                     /locus_tag="VVR39_001877"
     CDS             complement(10507..10728)
                     /locus_tag="VVR39_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031291.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKIDNLKEVIAKLKANA"
     gene            10808..11032
                     /locus_tag="VVR39_001878"
                     /pseudo
     CDS             10808..11032
                     /locus_tag="VVR39_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3295 a         2383 c         2101 g         3355 t
ORIGIN      
        1 gttccaggta ttatcctgat tggtgtttcc ttgcgaactc cttttactgt tttacccatt
       61 attttgggaa atatttcgca aggtctggag gtagaagtta gttcgcttgg tgtcttgacc
      121 agcctgcctc tccttatgtt taccctcttt tcaccatttt ctacccgact ggctcagaaa
      181 attggcttgg agcatctctt cacctacaac ctcttcttct tgaccatcgg ctcacttatt
      241 cgactaatca atctgcccct gctctatcta ggaaccttga tggttggggc aagtgtcgca
      301 gtcatcaatg tcctgcttcc tagtcttatc caagccaatc aaccaaagaa aattggtttt
      361 ctgaccacct tatatgtaac gtctatgggg attgcaacgg ctctggcttc ctatctagct
      421 gtgcccatta cacaagccag ttcttggaaa ggacttatcc tcctcctcac gttactctgt
      481 ctagcaactt ttttggtctg gctcccaaat caccgctata atcatagact agctccacaa
      541 accaaacaaa aaagtcaaat aaaggtcatg tgtaataaac aggtttgggc aattattatc
      601 ttttcaggtt ttcaatcctt gatcttttac accgtcatga cctggttacc taccatgtct
      661 atccatgcag gtctatccag tcacgaagct ggcttgctga cttctatctt atctctgatt
      721 agcattcctt tttcaatgac catcccaagc ctgacaacca gtttatctac tcgcaaccgt
      781 cagctcatgc tcactctggt ttcactagct ggtgtggtcg gcatttccat gctctttttc
      841 ccaatcaata atttcattta ctggcttgcc atccatctcc tcatcggaac cgcaaccagc
      901 gccctcttcc cttatctcat ggtcaacttt tcactcaaga caagcgcccc tgaaaagaca
      961 gcccaattgt ccggtctatc tcaaacagga ggctatatcc tagcagcctt tgggccaacc
     1021 ctctttggtt acagttttga cctgttccac tcttgggtac cagctgtagc tgccctcttg
     1081 ctcatcgata tcctgatgac tgtggccctc tttacagtgg acagagcgga taagatcctt
     1141 taaacttcta gttttagcta gaagtttttt atatataaaa attttacaca tttctcttga
     1201 cagggctttc ttttagatgt acaatatatg tgtagaaaaa ttatatataa aaatcttaca
     1261 cattagaaaa ggaggtttcc catgtacttt ccaacatcct ctgccttgat tgaatttctc
     1321 atcttggccg tactggagca gggtgattct tatggttatg agattagcca aaccattaag
     1381 ctgatcgcta atatcaaaga atccacactc tatcccattc tcaaaaaatt ggaaggcaat
     1441 agctttctga caacctattc tagagagttc caaggtcgca tgcgcaaata ctactccttg
     1501 acaaacggtg gtatagagca gctcttgacc ctaaaagatg aatgggcact ctatacagac
     1561 accatcaatg gcatcataga agggagtatc cgccatgaca agaactgaat acctgactca
     1621 gctagaactc tatctcaaga aactacctga agctgaccgt atcgaagcca tggactattt
     1681 cagagagctc tttgacgatg ctggagtcga aggagaagaa gaactcatcg ctagtttggg
     1741 aactcccaaa gaagcggccc acgaagttct atccaatctt ctcgataaaa aaatcaatga
     1801 agcacccgct caaaaaaata accgacaaat tttacatatc gccttgttag ccctccttgc
     1861 agcacctatc ggcattcctc tgggaatcgc catcctcgtg accctgttcg caatccttgt
     1921 agccgctttg actgtcattc tggctttctt tgcagtttcc atactgggta tcatcggcgg
     1981 attcctattt ttagttgaaa gtttcactgt cctcgcccaa gccaaatcag cctttatctt
     2041 gatttttggt tctggtttac tggctatcgg tgcttcttcg ctagttttac taggcatttc
     2101 ctatgtagct cgcttcttcg gtctactcat tgttcgcctg gtacaatttg ttcttaaaaa
     2161 aagaaagaga ggtaaccagc atgcgtaaat ggacaaaagg atttctcatc tttggtgtgg
     2221 tgactaccgt tatcggcttt atcctgcttt ttgtaggtat ccaatctgac gggattaaga
     2281 gcctactttc catgtccaaa gaacctgtct atgatagccg tacggaaaag ctaacctttg
     2341 gcaaggaagt cgaaaaccta gaaattactc tccaccaaca cacgctcacc atcacagact
     2401 ctttcgatga tcaaatccac atttcttacc atccatctct ttctgctcac catgatctta
     2461 tcaccaatca gaacgataga actctgagtc tcactgataa gaaactgtct gaaactccgt
     2521 ttctctcttc tggaattggt gggattcttc atatcgcaag tagctactct agtcgttttg
     2581 aagaagttat tctccgacta ccaaaaggga gaactctaaa agggatcaac atctcagcca
     2641 atcgcggaca aaccaccatc ataaatgcta gccttgaaaa tgcgaacctc aatacaaaca
     2701 gctatatcct ccgaattgaa ggaagtcgta tcaaaaacag taaactcaca acgcccaata
     2761 tcgttaatat ctttgataca gttcttacag atagtcagct agagtcaaca gataatcact
     2821 tccacgctga aaatatccaa gtccatggta aggttgaact gactgccaaa gattatctca
     2881 gaatcatcct agaccagaaa gaaagccaac gaattaactg ggacatctca agcaactatg
     2941 gttctatctt ccaattcaca agagaaaagc ctgaatcaag aggtacggaa ttaagcaacc
     3001 cttacaaaac tgaaaaaacc gatgtcaagg atcaactcat tgcgagatct gatgataata
     3061 ttgatctaat atccacacca agcagacgtt gacaaaaacg cttacatctg ctactatgga
     3121 agcatattta tctaactaaa aaggaggttc taccatgaaa caagaatggt ttgaaagtaa
     3181 tgattttgta aaaacaacaa gcaagaacaa gcctgaagag caagctaaag aggttgcaga
     3241 caaggctgaa gaaacgatag ccgatctcga tacaccaatt ggaaaaaata ctcaagtaga
     3301 ggaggaagtc tctcaagctg aagtcgaatt ggaaagccag caagaagaga aaattgaaac
     3361 tcctgaagtc ggtgaagcga gaacagaaat agaagaaaag aaggcatcta attctactga
     3421 agaagagcca gacctttcta aagaaacaga aaaagtcact atagctgaag agagccaaga
     3481 agctcttcct cagcaaaaag caaccacgaa agagccactt cttatcagta aatctttaga
     3541 aagtccttat atccccgacc aagctccaaa atctagggat aaatggaaag agcaagtgct
     3601 tgatttttgg tcttggctag tggaagcgat caaatctcct acaagtaagt tggaaacaag
     3661 tatcacacac agttacacag cctttctctt gctcattctg ttttctgcat cttccttttt
     3721 ctttagtatc tatcacatca aacatgctta ctatggacat atagcaagca ttaacagtcg
     3781 cttccctgag cagctagctc ctttaactct tttttctatc atctctaccc tagtagcgac
     3841 aacactcttc ttcttttcat tcctcttggg tagtttcgtt gtgagacgat ttatccacca
     3901 ggaaaaggac tggacgctag acaaggttct ccaacaatat agtcaactct tggcaattcc
     3961 aatcttcctc actgctattg ctagtttctt tgctttcttt gatagcctac gatttacagc
     4021 tctcttgtgt gtgattagca ttggaatcat tctgcttgcc agtctccata tcattacaag
     4081 accaagtcaa gcaagtgaaa ccgactcctt ctatcaatta ttcttgtctg tccttgtgaa
     4141 cggagttatt atcctcctct tctttgtagc tgaagtggca ctgattggag attatcttcg
     4201 tatcttggcc tttctttaaa cttcatactc ttcgaaaatc aaattcaaac cacgtcagct
     4261 tcgccttacc gtactcaagt acagcctgcg gctagcttcc tagtttgctc tttgattttc
     4321 attgagtagc aatcctgtca ttcttggcag gattttttct atgtcaaaaa agcaagtcga
     4381 ttgacctgct tctgctttac ttttcttgtg ctaatgtttt aaaatcttgt cctaggatgg
     4441 gttgtatttc tatttgattg gcgtctagtt ggtggtaaaa agatgggggt aatacctcta
     4501 agaattttgc atagtccaag cgagctatgg attcatagtc ttctggttta gagccgtctc
     4561 ctgtgatttg aaccaagtca atctcccact ggacttcctt atccaccaat tgctcaatat
     4621 aggctgcagg aacaaacggt tctctcggta aaactgtctt gactccttga gctagatggt
     4681 aaacgccatg cacttttcct tctccatcct gatagaagga aactctcgca aagtaggcat
     4741 ctgtctcttg aaccgcacgc acacgcgctt caaactgagc caagccatct gcctctaaaa
     4801 agcttttcaa gttctcacga ctaaagaaaa taggattaaa aattccttgg caaatcgtaa
     4861 aacgagctac agggtctgct agataggctt gaatacttgc ttggaaataa gcttcaaaat
     4921 caaaaccatc tagcccttca atatcagtcc ctgtataagc aagcaaagca tctaaaaatg
     4981 acttgataat cagccagtct gtctttgtta gtaggtcagg aagatcgaca cggtaagcct
     5041 tttgaccatc agcataactg accttaaaaa gaaattgtga ttgccccact atcgcacact
     5101 caatatattc gagacgatta agaggctgac ggagatagac tacatcatag ctatgtgact
     5161 ccaaaccgtc tagcaaggcc aagatcgatt tggcattcaa aatctcttgt tctcctaaaa
     5221 tgctctgttt atttggaata aaaaatgttt tcgccataac tggactcctt tgaaatcgct
     5281 tacatacagt ataccttatt tttctgaaag atacagaaac aaactttaga tttttgagta
     5341 caaagcatag aaaaacagcc cctgaggact gtttgatctt atacagtagc tgcttgatcc
     5401 aagctttcac cgatagcggc taggcgctcg atcacttcag cttgtgtcaa ttcatttttt
     5461 gaaacatagc ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg aaggtacttg
     5521 tcttcatttt cttctgatgt caagatacga cggttacaga agggatttcc acagttgaca
     5581 taacgttcac atggcgttcc atcaaaccag tctttcccta cgatagttgg gttgacatgg
     5641 ttgacatcaa cggcaatacg ctcgtcaaag acgtacattt tcccatccca aagctcacct
     5701 tgaacttctg ggtctttacc gtaagttgcg attcctccgt gcaattggcc aacatctttg
     5761 taaccttcac gaaccatcca gcctgagaat ttctcacagc gaacaccacc tgtacagtaa
     5821 accacgacac gcttgtccat gaatttttct ttgttgtcac ggacccattg tggtaactca
     5881 cggaagttgc gaatatctgg gcgaatagcc ccacggaaat gtcctaggtc gtactcataa
     5941 tcgttacgtg tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt gaactctttt
     6001 ggagacaagt aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct
     6061 tccaaaccaa ggtggacaat ttctttcttg tagcgaacaa acatcttctt gaaggcttgt
     6121 tcattttctt cgtcaatctt gaaccagaga tcttccattc ctggaaggct gtgaacgtag
     6181 tccatgtatt tttgagttgt ttcatagtca cctgaaactg ttccgttaat tccctcgtca
     6241 gcgactagga tacggccttt aaggccgatt gatttacaga aagccaagtg gtctgcagca
     6301 aattgctctg cattttcaat tggagtataa aggtagtaaa gtaagacacg aatatctttt
     6361 gccataagat ttgttctctt ttctattctt aaattttcta aattttttat ttatccatac
     6421 tagtatacct gcttgagaaa acgaatgcaa tttatttgac tggaaattgt agagggttct
     6481 cgaaatttcc tgaatggtta aaataaggac aagagaaaac atggatatct atatccttgt
     6541 gccaaaaaaa ccactgccct ccccagacca acctgaggaa agcagtgatt cttattttag
     6601 gagttaggaa tgaatacacg aaatcaattt agctgattat tttttgtttt tcaagaattc
     6661 atcgtattgt ttttgcattt cgttcaatac tttttcgtag gcaccttcag atttcaattt
     6721 ttccatcaat tctggaatag ctttatctgg gtctacagta ccagtgttga tagctgtatc
     6781 aaattgttgc attgtgttag caatagctga gatttcagat ttcacattgt cagtattgaa
     6841 gataaatcca agcgctggag attctttagc ttctgccaat tctttcttag aattttcgat
     6901 ttgttggtct gtaacgtttt cgttgatgta aaggatccag ttgttaccag tgttccatcc
     6961 acccatgtga gtgtttcctt tgtagccatc aagaacgcga acacggtttt ctttaccttc
     7021 aattttttcc cagttcttgc cttctggacc gtaaacaaga ccgttcaaga gttctggatt
     7081 cgtattcaag aggttcaaga tttccattga tttttctttg ttcttagagt tgtttgagat
     7141 gacaaagtta gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa ttggtttgat
     7201 ttggatatct ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag ctggtcctac
     7261 tgtttcttca cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc
     7321 gacgtctttt ggaatgtagc cagcttcata gaatttgtga agagtcttca agtgttcttt
     7381 gaaacgaggc acttcgtaac ggtttacaac tttagtagta tcgccttcaa ggtcgataac
     7441 gaatggaaga ccgtttgcta ctgggtagtc aaagttatca gatgggatga aaactttacc
     7501 aatagcaaat ggtactacgt ctggagcttt ttctttaatt tgtttcaaga ctggctcaag
     7561 agtttcgtaa gaagtaacac ctgaaatatc gataccatat ttagcaagga gagttccgtt
     7621 gaaggcaaag ttttgagatg acgcaacgtt ggctgcaact ggaacagcgt aaatcttacc
     7681 atttacagta ttacccttga tgtaagctgg gtcaagtgct ttgtaaaggt ctttaccttc
     7741 ttttttgtac aattctgtca agtcagcgta agcacctttt tgagcattta caatatagtt
     7801 atctgcaaag gcaatatcat agttttcacc agatgatgtg ataactgaca ttttcttacc
     7861 atagtcaccc cagccaaggt attggatatc caatttggca ccaacttttt cttcaatgat
     7921 tttgttggca tttgctaaca attcatccaa gttgtctggt ttgtcaccga tttggtacat
     7981 tttgataaca ggtttgtcac ctgaatcagc agctttttta ctgttacctg tcaagttgcc
     8041 acaagcagca agacctgcag ccaaagcgac tacactagca gatgcaaaag catatttttt
     8101 ccagtttttc atgataaaaa ctcctttttt tatttttaaa cttataaaca atgtaatgat
     8161 cttatactca atgaaaatca aagagcaaac tagaaaacta gccgcaggct gtacttgagt
     8221 acggcaaggc gacgttgacg cggtttgaat ttgattttcg aagagtatta acttcacaca
     8281 agggaagttg ggaactgaga aatgttcttt ttcaataagc actattcttt cacaccaccg
     8341 atagtcaaac cttttacaaa gtagcgttgg aagaatggat ataaaatcgc gattggaagg
     8401 gttgcaacca caaccatggc catacgacct gtttctttcg gtagagcaac tcccagttga
     8461 ccagtcaagc cgaccgcttt ggcaatgtag tccatatttt gttggatttg catgagcaaa
     8521 tattgcaatg gatacaagtt atcactcttg atgtaaagaa gggcgttgaa ccagtcattc
     8581 cagaaaccaa gagctgtcaa aagcgtgatg gttgcgatac ctggtagtga caatggcaaa
     8641 cagatttgga agaaaatccg ggcctcactg gcaccatcga tacgagccga ttcgagaatg
     8701 gcttctggaa tggtcttctt gaagaaggaa cgcatcaaga tgatgttaaa gggggagaga
     8761 agcattggca caatcaaggc ccaaacagtg tcaccaagct gaagtacacg ggtcaccatg
     8821 atataacctg gtaccaaacc agcgttgaac aacatactga gaaggacgaa gatggtaaaa
     8881 aatctgcgat acttaaaggt tgtccgtgaa atagcgtagg cataggttgt tgtgataaag
     8941 acatttgtca atgtcccaac tacggttaca aagacagaga tgaagagggc ttgtaggatt
     9001 ttatccttaa actgtgccaa aaactcaaaa ccgtctaagc caaattggga tgggaagaag
     9061 ctatagccgt attggaggag gcttttctcg tctgtcactg aaataatgat aacgaataca
     9121 aaaggtagga tacaagagag ggcaatcaaa cccgaaatga tactgaagaa gatatctgct
     9181 ttcttactga aggagtgaat gccgacatta tcaatttttt cttttttaat tttctttttt
     9241 gccatattct cctcctttct agaacaaagc tgagtttgga tcgactcgtc ttgcaagcaa
     9301 gtttgatagg ataaccagaa tcaaaccaac aacggattgg taaagaccgg ctgctgcagc
     9361 cataccgata tctgctgtct gagtcaaacc attaaagaca tatacgtcca aaacgttggt
     9421 tacattgtaa agctgaccag cattgtgtgg gatttgatag aagagaccga agtctgcgcg
     9481 gaagatattt ccgactgcaa ggatggtcaa tacagttaca agcggagtca actgaggaat
     9541 ggttacgttg cgaatacgtt gccacttgct agctccgtcc actgtcgctg cttcgtagta
     9601 ggttggatca attcccatga tcgtcgcata gtacatgaca ctgctatatc caaagccttt
     9661 ccaaatacct aggaaaagta ggagataggg ccagatgccc aggtcagcgt aaaaattgac
     9721 ttctttgaga ccaagacttt ccaatagatg attgaacacc cctttatcaa tatttaggaa
     9781 ggcatctgta aagaaactga tgataaccca agacaagaag taagggaaca acatagaagt
     9841 ttggaaaatc ttcaccattc tcttagaacg gagctcgctg aggataatgg caatccctac
     9901 agatacaact aaacctagaa agataaagcc aagattgtag aggacagtat ttcgtgtgat
     9961 aataaaggcg tctcttgaac taaataagaa tctgaaatta tcgagtccga cccatttact
    10021 atttatgata ctatctatga aaccattact ggtcatgtgg tagtctttga aggcaaccac
    10081 gttcccaaat actggaatgt aaaagaatag aatcaaccag agtgcccctg gcaaaaccat
    10141 caagagaaag atccagttgt ctctcaatgt ttttgaaaac tttttcataa tttcctccct
    10201 ttttattttg atatccatct aaaaattctt ttttagactt ttgataacga ttacattatt
    10261 agtatactcc tatttgcagg ttaggttaaa ctcctaatta tagaaaaaac tccacaaatt
    10321 atgtagcaga tttaaaactt tatcaccact atcaaacaaa tgtcctaaat caattgttta
    10381 ttttatctct attagcccag tgatggcgtc actctgttat aagtatccaa caacggggta
    10441 tactgaaaaa tctccagact agggaactca gcgatagttc ctaatctgga gatttttaat
    10501 atgttattag gcgtttgctt tcaacttagc aataacctct ttaagattat caatcttagt
    10561 tgctgactgg ctttccttaa tggactctag ggaagcaatg gcatctttga ctgtttgcaa
    10621 gatatcacgt aaaccttgct ctatcaaact atcatctgca aaagctttct tagcctctgc
    10681 caaaaccaga ggtgctgaat ctgtggtagg attcgataca cctgtcaatg atctcaaaag
    10741 attttctaag gtttgagtct gcttactaat actagactaa aatcaaaaag cattatataa
    10801 cagtgatatg aaatcaacta aagaagaaat ccaaaccatc aaaacacttt taaaagactc
    10861 tcgtacagct aaatatcata aacgccttca aatcgttcta tagtaaaatg aaacaagaac
    10921 aggacaaatc gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc
    10981 tattatattt cgtctgatgg gcaaatctta taaagagatt atagagcttt tatagtgatt
    11041 tgaaataaga tgtgaacaac tctatcagga aagtcaaatt aatttataga aatattttag
    11101 cagccaaggt gtactgttat aaattcaata cact
//
LOCUS       DAVHSL010000064        11048 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000064 DAVHSL010000000
VERSION     DAVHSL010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.066"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..574
                     /locus_tag="VVR39_001879"
                     /pseudo
     CDS             1..574
                     /locus_tag="VVR39_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(690..1493)
                     /locus_tag="VVR39_001880"
     CDS             complement(690..1493)
                     /locus_tag="VVR39_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU6031292.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1770..2525)
                     /locus_tag="VVR39_001881"
     CDS             complement(1770..2525)
                     /locus_tag="VVR39_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU6031293.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2595..5246)
                     /locus_tag="VVR39_001882"
     CDS             complement(2595..5246)
                     /locus_tag="VVR39_001882"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU6031294.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQGEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGCKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5239..5817)
                     /locus_tag="VVR39_001883"
     CDS             complement(5239..5817)
                     /locus_tag="VVR39_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6031295.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5817..6377)
                     /locus_tag="VVR39_001884"
     CDS             complement(5817..6377)
                     /locus_tag="VVR39_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031296.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(6364..6813)
                     /locus_tag="VVR39_001885"
     CDS             complement(6364..6813)
                     /locus_tag="VVR39_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU6031297.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7226..7621)
                     /locus_tag="VVR39_001886"
     CDS             complement(7226..7621)
                     /locus_tag="VVR39_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6031298.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7717..7971)
                     /locus_tag="VVR39_001887"
     CDS             complement(7717..7971)
                     /locus_tag="VVR39_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU6031299.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7981..9315)
                     /locus_tag="VVR39_001888"
     CDS             complement(7981..9315)
                     /locus_tag="VVR39_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU6031300.1"
                     /translation="MVDERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSESGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9315..9548)
                     /locus_tag="VVR39_001889"
     CDS             complement(9315..9548)
                     /locus_tag="VVR39_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU6031301.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9816..9956)
                     /locus_tag="VVR39_001890"
     CDS             complement(9816..9956)
                     /locus_tag="VVR39_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031302.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9953..10135)
                     /locus_tag="VVR39_001891"
     CDS             complement(9953..10135)
                     /locus_tag="VVR39_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031303.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10137..10920)
                     /locus_tag="VVR39_001892"
                     /pseudo
     CDS             complement(10137..10920)
                     /locus_tag="VVR39_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3242 a         2446 c         2050 g         3310 t
ORIGIN      
        1 taaaatgcga cagaaacgaa aataaaggag acgttggtaa gaaggcagag aatctcattc
       61 aaggccaatt tgaaggatct aaaacaatgg aaaagtgcta cacagatgtg acagaatttg
      121 ccattccagc aagtactcaa aagctttact tatcaccagt tttagatggc tttaacagcg
      181 aaattatcgc ctataatctt tcaacttcac ccaacttaga acaagtacaa acaatgttgg
      241 aacaggcatt cacagagaag cactacgaga atacgattct ccatagtgac caaggctggc
      301 aataccgaca cgattcttat catcggttcc taagagtaag ggaattcaag catctatgtc
      361 acgcaaggga aacagccaag acaacggtat gatggagtcc ttctttggga ttctgaaatc
      421 ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt aagcaattgg aacaagctat
      481 tgtagactat attgattact acaacaataa acgaattaag gtaaaactaa aaggacttag
      541 ccttgtgcaa tacagaacta aatccttcgg ataaattatt tgtctaactt tttggggtca
      601 gtacacctaa aactttgatg atatacgttt tcttgtgaga atatttactt catttttgcc
      661 taaaattcaa tgtttactca gtatttggat tatgaaaaat cgaggtctaa atctagatac
      721 attttttctg aagacaaatc attttgacca ccgagcaaga gattttcaaa aaaagctgtt
      781 aaaaactcag aacgtcgctg taaaatcttt gcattatcta ataccaaggc atcacgaaaa
      841 tatttggaat gttgctgaaa tggtgtatta tcaatatcaa aaccaaactc acgaagatac
      901 tgaatcaaaa agaccgttac tgtccgagtg tttccttcgc gaaatggatg aatctgccag
      961 attcctgaaa taaaatgctg gatttgttta accacatccg cctgagttag tgtcgcatat
     1021 gcaacttgtt tttcctgatt aaaatcataa tctaaggtca tttgaatcat ggagtaatca
     1081 gagtacacaa cactttcacc attcaaaaca ggttcattct ttgtgatatt ggtctgacga
     1141 aattgcccca ccggaataga gggttcaaat atatcttgaa acaactcctt atgaatagca
     1201 agtaaggtcg caggactaaa gctaaagcct cttcgagaca atagttctac aatacgtaga
     1261 gaaaccaagt ctgcctcttc cgtacttgca tcaatagtat ggtgataagc cgttgcatcc
     1321 tcataaacct gctcataagt cagttctccc cgggactgtt tctcagccaa agattccata
     1381 tacgctgatg gcactagatt gtcaactttc tgcagaccaa aacctatccg ccataaatca
     1441 cgcttcgctt cataagacaa gtttggattg tcaatgttgt aagttgattg catagaaata
     1501 tcctttcaat tgtttttctt cattaccagt aaatcacgaa attggttgga aactggctta
     1561 aactataaaa agtcctcaca ataggttcta tgatatatat atatacttca tgtaaataat
     1621 aaaagagtta taatcagcac tactgataaa ttcaataccg atttcgccat cttaaaactt
     1681 agtcaaacga ataccgttga tttccagttc attaagtcgt tgacctgtca agacttctcg
     1741 ttccttcaac tggaaaagtt aagggggaac taatacaaat cctctacgct tctatattca
     1801 atgatttcat ttttgataat attcttttta aactcaaaat gttttaaagg attatcgatt
     1861 aacactaact ttggaatatc atctagattt gtgaccaagg ataaaataaa atccgattga
     1921 aactccttga ctttttcaaa ttcttttgca gttaaacgca cacgcccctt agattttcgg
     1981 atacctttta cttcggcaag gtaagaatac tcttggacat ctacctgaaa gtcatatcca
     2041 tcaccataaa gacgggcatc ggttaactgt ccaccttgga atttttcttc tttatcaaaa
     2101 tgaaggataa aataattctc agcctccatt cccgtttcct gtagacgttt gaatttagtt
     2161 cgaactattg gtttttcaac gatggttatg cctgttttct tcccttcact ggcaagtaac
     2221 attttaacta tttcagcata actatgaaca tcttcatttc caaacatcat atcaattaaa
     2281 tctttacgaa aacgataaac ttcagctttc tgccaccaac cttttcgatt attgtcaaaa
     2341 taaggatcaa ataaatccat tctatttttt acaactccag ttgtttcagc aattcccaga
     2401 gaaaccacat agcgataaaa ctccgacttg ctagagcatt gaaattcttt tataaaaagc
     2461 ttgtcaaact tggcaagacc gtaaccaatt aaatttaaca attcataatg agggtgtttg
     2521 gacatcactt tctccatcaa tagatattga tttcattata ccaaaaaaca cggctcatca
     2581 ccgtgtttct gtgtttattt caccaacttc ttcatctcat caatacgtgc tacggtcgca
     2641 tcatacttag cttggtaatc tgcttgcttg tcgcgttctt tttggacaac ttctggttta
     2701 gcgttggcga cgaagcgttc gttgctgagt tttttgccaa ccatgtcgag ttctttctgc
     2761 catttggcaa gttctttttc cagacgtgcc aattcttctt cgacattcaa gaggtctacc
     2821 agtggcaaga agatttcggc tcctgtgatg acgcttgaca tagccagttc aggtgcaggg
     2881 atggttgatg cgatttccaa gtgttcagga tttgtgaaac gtttgatgta gttgacattg
     2941 ctgttaaaga aggcttccaa gtcgctatcg cttgtcttaa caaggatagt gataggcttg
     3001 cttggagcaa cgtttacttc cgcacgcgca ttacgaacgg cacggatcaa gtctttaagg
     3061 ctttccacac cagtgtgagc agcaaggtct tcaaaggctg ggttgacagt tgggtattct
     3121 gctgtaacga tagatccttc tgagatttgt ccaaagattt cctctgtcac aaatggcatg
     3181 attgggtgaa ggagacgaag gatcttgtcc aaagtgtata gtagaacaga acgtgtgatg
     3241 actttctctt cttcgttatc gctataaagg acttccttgg tcaactcaac ataccagttg
     3301 gcaaattctt cccagatgaa gttgtaaagg atatgaccag ccacaccaaa ctcgaactta
     3361 tcaaagtttt cagtaacttt tgcaatggtt tcgttgagat tgtggagaat ccagcggtcc
     3421 gtcacattac cagcctcacc tgttgcaact tttgtgacat tgtcatgcgc cacatccagc
     3481 gtcaaacctt cattgttcat gaggatatag cgagaaatgt tccaaatttt gttaataaag
     3541 ttccatgaag catccatttt ctcgtaagag aaacgaacgt cttgaccagg agctgagccg
     3601 tttgacaaga accaacgaag actatctgta ccatatttat caataacatc cattgggtca
     3661 atgccatttc caagagattt agacatctta catccttctt catcacgaat tagaccatgg
     3721 ataaggacgt tttggaatgg ttgacggcct gtgaattcca atgactggaa gatcatacga
     3781 gacacccaga agaagatgat gtcgtaacct gttaccaagg ttgaagttgg gaaataacgt
     3841 ttaaagtctt ctgagtcgac ttcaggccag cccatggttg aaaatggcca gagggcagaa
     3901 ctgaaccaag tatccaagac gtcttcgcct tgagtccatc cgtcaccttc tggagcttct
     3961 tcgccgacat acatttcacc atcagcattg taccaggcag ggatttggtg accccaccaa
     4021 agctgacgag agataaccca gtcgtggaca ttttccatcc attgaaggaa ggtatcgttg
     4081 aaacgaggtg ggtagaattc gaccttgtcc tctgtgtctt ggttggcaat ggcgttctta
     4141 gccaattggt ccatcttgac gaaccattga gtagacaagc gtggctcaac tacgacacct
     4201 gtccgttctg agtgaccgac tgaatggaca cgtttttcga ttttgacaag ggcaccgatt
     4261 tcttccaact tagcaacgac tgccttacga gcttcaaaac gatccatgcc tgaaaattca
     4321 aaggcaagct cattcatagt tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga
     4381 cgttggccaa ccaagaagtc atttggatcg tgggcaggtg tgattttcac gacaccagta
     4441 ccaaactcag gatctgcgtg ctcatctcca acgattggga tgagtttatt agcgattgga
     4501 aggatgacgt ttttaccaat caagtccttg tagcgcgggt cttctggatt aaccgcaacc
     4561 gcaacgtccc caaacatagt ctcaggacga gttgtagcaa cttcaagggc gcgtgaacca
     4621 tcttccagca tgtagttcat gtggtagaag gcaccttcga catccttgtg aatcacctca
     4681 atatcagaaa gggctgtgcg agctgctggg tcccagttga tgataaactc accacggtag
     4741 atccagcctt tcttgtaaag gtccacaaag accttacgaa cagcttttga caaaccttcg
     4801 tcaagagtga aacgctcacg agagtagtct acagagagcc ccatcttgcc ccattgttcc
     4861 ttgatagtag tggcatattc gtctttccat tcccagactt tcgtcaagaa agactcacga
     4921 ccaaggtcat agcgggaaat gccctcacca cgcaagcgct cctctacctt agcctgagtg
     4981 gcaatccctg cgtggtccat cccaggaagc caaagggtat caaaaccttg catgcgtttt
     5041 tgacggatga taatatcttg caaagttgta tcccaagcgt gaccaaggtg aagtttacct
     5101 gtaacgtttg gtggtggaat aacgattgaa taaggcttag ccttttgatc gcctgaaggc
     5161 ttgaaaacat cagcatcaag ccatttttgg taacgaccag cctcaacctc ggctggattg
     5221 tatttagatg aaagttcttt agacatgtgt gtgtcctttc tctattttgt ttattttatt
     5281 ttgaatttgc ttagcagctt cttctgcaga caaattcgta ttatttattt taaagtagtg
     5341 gtgcaactca ttcggttgat attgggaatt taattgaagt gtttcagcgg tctctaaaat
     5401 ttctctttca gatacctcaa tatgtcgttt taagggtttg tgctttaatc gattctccgt
     5461 tcgatttcga cgtatgcact cttcaagact tgtttccaac tcaacaaaaa gaatctcttg
     5521 atgataatca tccaacaaat tctgaatttg ctttaaatat atcagatgat actgatttga
     5581 aaaatcaatt acatctgtta aaattactga tcgctgattt cttgcacttg ctccaaggaa
     5641 tgaaaaagtg attccacgaa caaattccca catttcctct gtatagtcct gatagatttc
     5701 tagtgcaaaa tcaatggctt gatggttata aaatagggta gcatccgtca gtcgagataa
     5761 ttcttgacca atggtcattt ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa
     5821 atcacccccc actcactctt cagcaaggca tatctcaaat catcacagca gttgccttga
     5881 gcatctttac ggtctcttat gcgagcttcg agggtaaagc caagcttttc cgcgactcgt
     5941 tgactttgaa ggttatatcc aaagcaagtt agttcaatct tgtgaagacc caaatcttta
     6001 aaggctaagt caatcaaggc acgcgcagct tctggcacat aacctcgccc ccaatagtct
     6061 gagtgtaagg tatagccgat ttccatcaca tcatcttcat ggcgatggtt gaaatagata
     6121 gagccaacga tcttatccgt tcctttgacg acaatcccgt agcctgctgg gagattttcc
     6181 ttttgattac gctccggaag aatgtgctcc agataataaa tctcatcttc caaggtcttg
     6241 actggaggaa aacctgctgg ataggcgacc tctggcaaac tagcatagtc aaagatatcc
     6301 tcagcatccg ccacagtacg gactcgtaaa acgagacgtt ctgtttcgat tttatctggc
     6361 agctcagttc ttgccatcct tcttcctcgc ttttttgatg aaactgccct tcatatctac
     6421 acgcttgtcc agatagcgat aaacgcgctg atatccatct cccatgaaat atgttggggc
     6481 aaacagttga tttttaaaat gtcccttttc atccaggagt tctggggcaa caagtcgctc
     6541 aagaatcttg gcaaagatgt ggcaaatacc gtcttcctca acaatcctat ctacccgaca
     6601 atctaaaaca agtggacagg cgtctaaaat aggagtctga gttcgttcag aaatttcata
     6661 atgcactccc aaacgttcca atttctcctg atgactgata aaaccagcct gctccatcgc
     6721 aagcatagaa gtttcatcag aaatattcac agtaaatttt tgatactgtt tgatctgctc
     6781 tgcggcattc tctctcgcaa cgactccaat cacaacccaa tctcctagac tataagagga
     6841 actacaggtc gtgatgttat agccaaaatt ctaatcttga tatcctaaaa taaaaacagg
     6901 aaaaccataa tatagtttac ttgtgttaaa agattgcttc ataacaaccc cctttgacta
     6961 agacgtaaaa gaaaagccct gccatctaca tgacagggac gaatctgttt atccgcggta
     7021 ccacccaatt tcgggcagtt gcccgcaact ctcgtcttta aagcaaaaag acacttttat
     7081 ttcaattttt catccattag caaccagttt tgacacattt gtggacttct cagcgccgcc
     7141 actttctgta aaatgtggga ttcaaaacac ctctaatggc tctattgtag caagattttt
     7201 tcggaaatgc aaggctcaag aaaaattact tgaacttgat gccattttct ttcaatttct
     7261 tgatggtagc tgggccgatt cctttcaagt caaggagttc tttttcagtc cagtttttga
     7321 aatctgaagc agacttgatt ccttcatcat agaaagtctt ggcacgatca agtggaagtc
     7381 cacccaaatt tgctgcaaaa tcttctacag aattagctac tttttgagct tgctctttgg
     7441 tagcttctac tgcttgttca acttttttag aaacagcctt accagctgcg cttgctgact
     7501 gttctgcacg cttcacgact ttttttgtct catctacaac cttagtcaca gtacttgaaa
     7561 aggcacctgc gcgacggagg ccatttcgta attgtttttt acgattgagt ttctttgaca
     7621 tgataaaatc ctttcaataa aaaatccctg ctctgacaag gatttaacat aaacattcta
     7681 tcaagatttt agtgaaaaat caagaatctt tctcgtttaa taatttcgct caccaaacaa
     7741 gccttctggc aaatcatgga atcccttgcc tactttgaag ttttcaaact taccaagcaa
     7801 gaactgataa gcatccaagc gactctcgta gcgaatcatg gcatctttgg cacgctcgtc
     7861 ctggtcttct tcgtaaactt tttgactttc cttgtgcgcc atatcgttaa tcatgatttg
     7921 ggtattgacc caagcttcaa attccttcat aaattcttgt tcgtaactca ttttttctcc
     7981 ttattctaat ccacgaaaat agtccgtatc aatctcacgg tagggctgga tatcctgaac
     8041 atactccaac actccttgga attctccgtc ttcatcgtgt actgcagcat aggtgatgtg
     8101 gacaaactta cctcgcgact cagacttgaa ccacatttca tacttgtctt tgcttccctc
     8161 acgaagcccc ttcatgatag ttttgacctt gtccaagtac ttaggcggat ggcagagttc
     8221 gacattgcgc ccgacttggg acggtgtccg tttgaaaatc atctcatcag ctggcgtatt
     8281 gtcattgtaa tactggaaaa tatcttcttt attgacaaag gtaatctcca tagggagatg
     8341 attgaggatg agattggcct gctcgactga aagatagcca ttaccaaaag cctgttgact
     8401 atggcggtcc agcacagctt ccttttcctt aggggtaaag gtaatggtaa aatggccttc
     8461 tggcgtatct atgacttgtt gaacttgacc ttctgccgta tctagctgta caggttcctc
     8521 tgcaatcttt tcctcaataa agctctgtcg ttctggcacc catttctctg acggacggat
     8581 gatggcatag ccataggcat cgctctcctc cgcaatctga agccagtcat cctgagtaaa
     8641 agactcaagg agaatcatga ggaggatgga ctcttccttg aaaatcatac tttcaaactc
     8701 tgtcgcaaaa gcttcaaaag cttcctttac actgctaatt gacacttctg gtagtgactt
     8761 ggctgtcgtt agagctgttt gaaagagttc cctaatctga tcatccactc cccacataac
     8821 tttgggaggt gaatcgtgtc catagcgctc catgatagga aagaagagtt cttccttacg
     8881 ttggtaatgg atgtcaaatt gacccacaag tcccatctga cgcaccaaac ccttacgcat
     8941 ctccgccagc atttcctcgt cttccataga ctcataggta tctaacaatc tacgaatgcg
     9001 aatcaaggcc gcacggagag ccagattttc ttctttgaag acacgaactg ggtgacctgg
     9061 atgctcagta tctgaaactt cgacaccttt gatagcattt ttaaaaagat tggcatggac
     9121 atcacagagt tccataacat cttcaaaggt gacacctgac tctgagttca tcagctcgtg
     9181 ctccataagg gaaatctcaa tggctgagac acccgcaaag gtcgcatcaa aacgctcctg
     9241 aaccgactca ggagaggcgc cattatgcaa ttctaataaa atatcccgta ggacatgaat
     9301 ccgttcatct accattagtc taatccaatc acttcgtagc cattcgcttc cagtgtgcgt
     9361 acaatcttgt ccataggagt tcctgctagc ttagaacctt gtttaagtga tactttacga
     9421 ccaactgtat tgcgcatcaa gggattggca aggggtttaa aacccagctc cactagaatt
     9481 tccaagactt ctggatgctt gtccaccact tctgcaacag gaattgacac atcgatgata
     9541 ttgtccatga cgacctccat tgtatgttct aatactcaat gaaaatcaaa gagcaaacta
     9601 ggaagctagc cgcaggttgc tcaaaacacc gttttgaggt tgtggataga actgacgaag
     9661 tcagtaacat atatactgca aggtgaagct gacgtggttt gaagagattt tcgaagagta
     9721 taaaatgatt ttactgctta tattatacca tatggagaga gattaaaaaa ctagcagtgg
     9781 agttcctgct agttttctgc gacttggatt accatctaga taagtttaaa gaaccaatcc
     9841 aatatcttgt aaaacagcaa ttgaactgca aaagaaatga tcatccaaaa gaatttcaca
     9901 atcccaataa tcggtttgat aaaaagaata gcaagaattg tccagaaaaa tttcattctc
     9961 tctcctctgg cttaatgagc caccgagccg tatccattag cttatctgca ataaagagtt
    10021 ttcccagacc aacaacgaca tggtcatctt tctttatcgt tttcatcact tttacacctt
    10081 gcacggtcaa aaagtaatta ccataaattt tagcaaaagc tttgatagga ttcatattat
    10141 tctcctttga tgatttcagc ctcttttcgg attgtttcaa catcttcttg atattgaact
    10201 tcactatagt tgactagctt ggataattct ttctgcaagc tttcccccat tggtttcata
    10261 gttgcaaagg ttaaaccacc tgaaatgata ccacccaaga taggaataaa tttccccatt
    10321 cctttggcca accctccctt ggtaagattc acaccaaata tttttaagac ttttttcaaa
    10381 atagggtacc aaagcgtctt tgttaaagct ttattaggca ctgttttcat tacctgtttg
    10441 gcaattgtta taccaccagc acgtagcaaa caaagcagcg gttccattca cccctaacat
    10501 tacgcctaga taaagcaaga gggtattttg agcatcttca ctcaactcct cacgtgaagc
    10561 ccaaagatcc tcataaccat aaatataacc taattcttgg gccaatttca gagagaaacc
    10621 ataaaattga gccacataag ctggaatggt aattgccata gcaagccctc caggtaatcc
    10681 tgccaaaaca gaagtcccac tcgctaataa aacattatcc ctaatacagg cattagccac
    10741 tcgatctaag atttcttgag ataagagaga cgttggacct tgttccaata aggtaggaat
    10801 gtcctgtgga cccaattctt tggaaaactt atccactaaa aatttcgaac gatcaacctt
    10861 aacaactggt agttttacca cttgttgtaa tacttgcata gctaagtctt gttcagccat
    10921 atacaaactc cttatttctt ttttgcacct tatcatatta tatttcctac aaaaaaagca
    10981 ttttctaatt agataacatt aaaaaataca gaaccccttt tttatagtaa aataaaacaa
    11041 gaacagga
//
LOCUS       DAVHSL010000065        10854 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000065 DAVHSL010000000
VERSION     DAVHSL010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.067"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(87..230)
                     /locus_tag="VVR39_001893"
     CDS             complement(87..230)
                     /locus_tag="VVR39_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6031304.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKYLHISPKKLKSLGR
                     IVK"
     gene            complement(611..838)
                     /locus_tag="VVR39_001894"
     CDS             complement(611..838)
                     /locus_tag="VVR39_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEU6031305.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKEPHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            complement(842..1225)
                     /locus_tag="VVR39_001895"
     CDS             complement(842..1225)
                     /locus_tag="VVR39_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6031306.1"
                     /translation="MIHKIRFEQFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAEGLTKQERFAILDSLESPHTQHGIVNSYKRLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            complement(1558..2334)
                     /locus_tag="VVR39_001896"
     CDS             complement(1558..2334)
                     /locus_tag="VVR39_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU6031307.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            2456..3202
                     /locus_tag="VVR39_001897"
     CDS             2456..3202
                     /locus_tag="VVR39_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6031308.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            3215..4195
                     /locus_tag="VVR39_001898"
     CDS             3215..4195
                     /locus_tag="VVR39_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU6031309.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECIFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4390..4710
                     /locus_tag="VVR39_001899"
     CDS             4390..4710
                     /locus_tag="VVR39_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6031310.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4756..5064
                     /locus_tag="VVR39_001900"
     CDS             4756..5064
                     /locus_tag="VVR39_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6031311.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            5081..6379
                     /locus_tag="VVR39_001901"
     CDS             5081..6379
                     /locus_tag="VVR39_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6031312.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6530..8968
                     /locus_tag="VVR39_001902"
     CDS             6530..8968
                     /locus_tag="VVR39_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU6031313.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMFIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8987..9655
                     /locus_tag="VVR39_001903"
     CDS             8987..9655
                     /locus_tag="VVR39_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU6031314.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9673..10761
                     /locus_tag="VVR39_001904"
     CDS             9673..10761
                     /locus_tag="VVR39_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU6031315.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3548 a         1527 c         2194 g         3585 t
ORIGIN      
        1 ttaatttgac tttcctgata gagatgttca catcttattt caattcacta tattagggta
       61 aaattctcta caaaaagaag aatagcctat tttactattc ttccgagtga tttcaatttc
      121 tttggggaaa tatggagata ctttttaaat actttggcaa aatatttata gtctgaaaat
      181 ccaacttggt cagagatagc gcttaaaggg gagttgggag attcagccat cttatctata
      241 gcttgtttca ggcgatattg taagatatat tcatttagag tcatctttga taaccttata
      301 tagatagctt tcgctatagt ttaaagcttc agcaatagta atgctctaca tagtgcttgt
      361 ggacaaagga gataatttgt tgaatgattt ggttttgtgt atcaacctgt tggatagagg
      421 tgagtaaagt ttgatattct tctaaaaaag gagtttcttg agatgtgcta atttgtaatc
      481 gcaaaacaat tttttgaaga cattctgtca attccttggt atcaattggc ttgaataaga
      541 aatcaactgc tccatattgc atggcttttt ggcattttga aaatcgttat aacctgataa
      601 gataactttt tcataagaaa gagtacgagt ggctttgaac atcataaaag catccataat
      661 tggcattgtg atgtctgtta agacaaatat gaggttcttt ttcttggatg agtttcattc
      721 cctcttgacc gtgactggca gttcctacga cttggatgcc taaggcagag tagtctacgg
      781 caatctctag ccattttcgg atgaggtgtt catcttctac aataatgagc ttaaacatga
      841 gttagtcttt cgttacaaat ttgacccaag tttctccttg gcgattgact cctaaatcta
      901 gctggacatc agaaaagaaa ttgctcaatc gtttgtagct gttcacgatg ccatgctggg
      961 tatgagggct ttctaaagag tctaaaatag cgaatcgctc ttgtttggtg agtccttcag
     1021 cattatcctt gactaaaaaa gttagagaat ctgcttccaa ggtaatgtgg atatcaatat
     1081 gaagatcaat acggtattgc atcccatgtt ttatagcatt ttctactaga ggaagcaaga
     1141 aaagtttagg gataggctga ttatcgacag tttctgggca gacaatatca taggaaaact
     1201 gctcgaaacg aatcttatga atcataaggt aatcctctat aatctttaaa tcctgacaaa
     1261 tggttgtttc tttttctaaa tcggtgatac tgtatcggag aatgcgcgtg aggtcacaaa
     1321 ggctgcgata gagcttctat ggagaatttc tttttggaga aattttttaa aggaatgaga
     1381 catccgctac ctccttggaa gggttttttg tgataagtat agcagtttaa aaattctaga
     1441 gcaaggtaaa atagaaaagg tttggctaaa attttttagc taaacctttt gaaaagttaa
     1501 gtatgtatta tagatgcttg ttatctgcaa atagctagag catttcaagg aaatgaacta
     1561 gaaataacaa ttaatatggt ggttcagaaa taccttttga taatcaataa gatcttcagg
     1621 atgaagtgcg ttgactccat ccatttcata tttccgattt aataaacgat atttgttttc
     1681 accaaattga tgaaaaggga gtagttgaac ttggtcgata tttaatgagt taaatagagt
     1741 agcgaatttt tctgcatcct ctaaactatt gttaaaatta ggaataactg ggattcttaa
     1801 aacgatagtt ttattttgag aaaaagcata atgaatgttt ttaataatca tttgattaaa
     1861 aaccccagtc acttttttat gttttataga attataatgt tttaggtctg tgtagataaa
     1921 atccacatat tgaattaaat caataaattt ttcatgatca acaaaggcag tagtttcaat
     1981 ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg gctttagcaa attcaaactg
     2041 agcaaatatt tcacctcctg ataaagttaa acctccaccg gattcttcgt aaaattcttt
     2101 gtcttttaat acctctgtaa taatttcttc tacagtcttt tcttcaccga ctaaggtgaa
     2161 tttctctcgt tgagcatctt tcattttttc aggtttcatt ctttgagatt caggattaga
     2221 acaccatgga cagcgcagag gacatccttt taaaaaaaca gttgtacgaa tacccgggcc
     2281 gtcatgaatt gaaaagtgtt gaatattaaa aataattcct ttagatattt ccataagagt
     2341 tcctcctctt cataagtcta tcctatcaca aaaacgaaag aaaaacaatt acgaacgaaa
     2401 gtttaatttg ttgttttttg ctttttattt tggtagaata aaacggaggt gtaaaatgaa
     2461 aagattggaa caaattatta aattagtatc agaatatgaa aagatcgacg ttaatacatt
     2521 atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa gatttagata aattagagtc
     2581 aaaaggttta ttacacagag agcatggata tgctgtatta aatagtggag atgacttaaa
     2641 tgtacgtttg tcaattaatt atgaaattaa gagaaaaatt gttcaggaag cagtaaaatt
     2701 ggtgtcagat aatgaaacaa taatgataga atctggatcg acctgtgctt tacttgctga
     2761 ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca aattcgtttt ttatagcaaa
     2821 ttttgtgaga gcttatgatt catgtcgtat tattgttctt ggtggagagt ttcagaagga
     2881 ttcacaggtt actgtgggac ctttattaaa agaaatgata cagacttttc atgtgcgtca
     2941 agcttttgtt gggacagatg gttacgataa agagatgggc tttacaggaa aagatttaat
     3001 gcgcagtgag gtagttcaat atatttcagc agcgtcggat aaagtcattg tactaactga
     3061 ctcaagtaaa tttgataaaa ggggtacagt aagaagattt gctttaagtc aagtctatga
     3121 agtaataaca gacgaaaaac tttctaaaca aaatatagct acattagaaa atgctgggat
     3181 aatggttaag gtagtttcgt aagaggttaa gtgtatgaat caagatagga ataaactgct
     3241 ttctaaaatt gcttatctgt attatattga aaacttaaat cagtcacaaa tagcagcaaa
     3301 attaggaatt tatagaacct ctattagtag aatgttaaca gaagcaagga atgtaggaat
     3361 tgttaaaatt gaaatagaga attttgatac caatatgttt aagttggaaa attatgtaaa
     3421 agaaaaatat ggtctggaaa gtttagaaat tattccaaat gaatttgatg ataatccaac
     3481 aattttatct gaaagaattt ctcaagttgc agcaggtgtc cttaggaatc taattgatga
     3541 taatatgaaa attggctttt cttgggggaa aagtttaagt aatttagtag atttaattca
     3601 cagtaaaagt gtccgaaatg ttcacttcta tcctctagca ggtggtccta gtcacataca
     3661 cgctaaatac catgtgaata cactgattta tgaaatgtct agaaaatttc atggagagtg
     3721 tatatttatg aatgcaacga ttgtgcaaga aaataaattg ttagcagatg gtattttgca
     3781 atcaagatat tttgaaaatt tgaaaaatag ttggaaagat ttagatatag ctgtagtcgg
     3841 aattggtgat tttagcaata aaggaaaaca tcaatggtta gacatgctta cagaggatga
     3901 ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt tgttgtcgat tttttgattc
     3961 aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg atagcaatct ctttggaaga
     4021 tttaaaaaat attcctcaaa gtttagctgt tgcttacggt gatacgaaag tatcttcgat
     4081 tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt acagacaaaa atacaatttt
     4141 aaaagttttg gaagaagatg gggatttgac ttttagagag attctaggtg agtgaaaatg
     4201 atagactgat tcagtttatc gtttttcttt ttagttgatt gcacatttgt gcttatataa
     4261 acaaaaatag tttatctgtt gtttttggat tgacaacttt attatgtagt tgtattctat
     4321 agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc tttttacata gtgaaatgag
     4381 gaggaattta tggaaattat tgttccagat caaattatca tgggtttaat tttatatgct
     4441 ggcgatgcga aacaacatat ttataaagcg ttagattaca taaaaaatgg tacatgtgaa
     4501 cgatgtgaag aagaaatcca gttagctgat gcagccttat tagaagctca taatctacaa
     4561 acaaaattct tggcacagga agcgtctggt acaaagacag aaattacagc tctctttgtt
     4621 cattcacaag atcatctcat gactagtatg acggagatta atttaatcaa agaaattatt
     4681 agtttgagaa aagaacttca taaaaaataa tactagagta ttatcattgt tattaacata
     4741 gaggaggaaa acataatggt gaagattggt ttgttttgtg cagcaggttt ttctactggt
     4801 atgcttgtaa ataatatgaa aattgcagcg caagctagtg gagttgaggc agaaatagag
     4861 gcgttttctc agtctaaatt agcggattat gcgccaaata tagatgttgc actattgggt
     4921 ccacaagttg cttatacatt agataaatca aaagaaattt gtgataagtg tgatgttccg
     4981 atagctgtta ttccgatgat ggactatggt atgttagatg ggaaaaaagt attagatttg
     5041 gccctatctt tgattagtgg gtaagaaaag gagatttatt atgtcaaaga tggatgttca
     5101 gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt ggcattatag ctctaaaaga
     5161 tgggatgtta gcaattttgc cattgacagt agttggtagt ttgttcttga ttatgggaca
     5221 attgccgttc gaaggattaa ataagagcat tgctagtgtt tttggagcta attggacaga
     5281 gccgtttatg caagtatatt caggaacttt tgctattatg ggtctaattt cttgtttttc
     5341 aattgcctat tcttatgcta agaatagcgg agtagaggct ttaccagctg gagttctatc
     5401 tgtatctgca ttctttattt tgctaagatc atcttatatc cctaaacaag gtgaggcgat
     5461 tggggacgct attagtaaag tttggtttgg aggccaggga attatcggtg ctatcattat
     5521 aggtttggta gtaggaagta tttatacctt ctttataaag agaaaaattg ttattaagat
     5581 gccagaacaa gttccacaag ctattgccaa acagtttgaa gcaatgattc cagcatttgt
     5641 aattttctta tcttctatga ttgtatatat tttagcgaag tcattgacta atggcggaac
     5701 attcatagaa atgatttatt ctgctattca agttccgttg caaggtttaa ctggatcttt
     5761 gtatggtgct attggaattg cattctttat atcatttttg tggtggtttg gtgttcatgg
     5821 gcaatcggta gtaaatggag tagtgacagc tctgctttta tctaatcttg atgctaataa
     5881 agctatgtta gcctctggta atctatcatt agaaaatggt gcacatattg ttactcaaca
     5941 atttttagat tcatttttaa ttctatcagg ttcagggatt acgtttggtc ttgtagttgc
     6001 catgcttttt gcagcaaaat caaaacaata ccaagcctta ggaaaagttg cagcttttcc
     6061 agcaatattt aacgtaaatg agccagttgt atttggattt ccgattgtca tgaatccagt
     6121 tatgtttgta cctttcattc ttgttcctgt acttgcagct gtgatagtat atggagctat
     6181 tgcaacaggt ttcatgcagc cattctcagg ggtaacattg ccttggagta caccagctat
     6241 tctatcagga tttttggtgg gtggatggca aggtgttgtg actcagttat tagtattggt
     6301 gatatctaca gtggtttact ttccattctt taagatacaa gatcgtttag cttaccaaaa
     6361 tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt aaactcacac atttgtgcta
     6421 aaaattagag agttaaaatt tttctagtta aaagcttgaa aatttctata aaaatcggta
     6481 ttatattttc gaaagaaata aaaatatttt cgaaagaaag gtgcttacga tggtaaatac
     6541 agaagtagca agaacaacaa tcaagacaga atattttggc agccttactg aaaggatgaa
     6601 caaatatcga gaagatgttt taaataaaaa accttatatt gatgctgaga gagcagttct
     6661 agcaacacgc gcctatgaac gatacaagga acaacctaat gtcctaaaac gtgcatatat
     6721 gctgaaagaa attttggaaa atatgtttat ctatattgaa gaagaatcta tgattgcggg
     6781 aaatcaagct tcttccaata aagatgctcc tatttttccg gaatatacac tagaatttgt
     6841 tctcaatgag ttggatcttt ttgaaaagcg tgatggagat gttttctata ttacagaaga
     6901 aacaaaagaa caacttagaa gtattgctcc gttttgggaa aataataatt tacgtgctag
     6961 agctggtgcc ttattacctg aagaagtgtc tgtttatatg gaaacaggat tcttcggtat
     7021 ggaaggtaag atgaattctg gagatgctca cttagcagtt aactatcaga aacttttgca
     7081 atttggttta agaggttttg aagagcgggc tcgtaaagcg aaggtagctc tagatttaac
     7141 agatccagca agtattgata aatatcattt ttacgactct atatttatcg taatcgatgc
     7201 tattaaagta tatgcaaagc gctttgttgc tcttgctaaa agtttagccg aaaatgcaaa
     7261 tcctaaacgt aagaaagaat tacttgagat tgcagatatt tgctctagag tcccatatga
     7321 accggcaact acttttgcag aagctattca atcagtttgg tttattcaat gtattttaca
     7381 aattgaatct aatggccact ctctttcata tggccgtttt gatcaatata tgtatccata
     7441 tatgaaggct gatttagaaa gtggtaaaga aacagaagat agcattgttg aacgtctgac
     7501 aaatctttgg attaagacaa ttacaattaa taaggttcgc agtcaatcac atacattttc
     7561 ttcagcagga agtcctttat atcaaaatgt tacaattggt ggacagactc gagataagaa
     7621 ggatgctgtt aacccattat cttatttggt attaaaatca gttgcacaaa cccatctacc
     7681 gcaacctaat ctaactgtac gttaccatgc aggtttagat gctcgtttca tgaatgagtg
     7741 tattgaagtg atgaaacttg gttttggtat gcctgcattt aataatgatg agattattat
     7801 tccttctttt attgcaaaag gagtattgga agatgatgct tatgattaca gtgccattgg
     7861 atgtgttgaa acggcagttc cggggaaatg gggctatcgt tgcacaggta tgagttatat
     7921 gaacttccct aaggttctac ttatcacgat gaatgatgga attgatccgg cttcgggtaa
     7981 acggtttgca ccaagctttg gtcattttaa ggatatgaag aacttttctg aattagaaaa
     8041 tgcttgggat aaaacactaa gatatttgac acgaatgagt gttattgttg aaaattctat
     8101 tgatttatca ttggaacgag aagttcctga tattctatgt tcagcattga ctgatgattg
     8161 tattggtcgt ggaaaacacc ttaaagaagg tggagcagta tatgattata tatcaggatt
     8221 gcaagttgga attgcaaatt tgtcggattc attagctgca attaaaaaat tggtgtttga
     8281 ggaagaacgt ataagcccaa gtcagctttg gcatgcactg gaaacagatt atgccggaga
     8341 agaaggtaag gtcattcaag aaatgttgat tcatgatgca cctaagtatg gtaatgatga
     8401 tgattatgct gacaaattgg ttactgctgc ttatgacatt tatgttgatg aaattgctaa
     8461 atatcctaat acacgttatg gaagagggcc tattggagga attcgttatt caggaacatc
     8521 ttctatatca gccaacgtag ggcagggacg tggaacatta gcaactccag atggacgcaa
     8581 cgcgggtaca ccgttagcag agggttgttc accatcacat aatatggatc aacacggccc
     8641 tacatctgtt ttaaaatctg tttcaaaatt accaacagat gaaatcgtag gtggggttct
     8701 cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa gaagataaat taaaactaat
     8761 tgctttgtta cgaacattct ttaatcgttt acatgggtac catattcaat acaatgttgt
     8821 ttccagagag acgttgattg acgctcagaa acatcctgaa aaacacagag acttaattgt
     8881 tcgtgttgca ggatactctg cattcttcaa tgttctttct aaggcaaccc aagatgacat
     8941 tataggacgt actgagcata ctttgtaaaa taaagaggtt ctttttatgg aatttatgct
     9001 tgacacatta aatttagatg agattaaaaa gtggtctgaa attttgccgc tagctggggt
     9061 aacttcaaat cccactattg caaaaagaga gggttctatt aatttttttg aacgaatcaa
     9121 agatgtaaga gaattgattg gctccacacc ctctattcat gttcaggtga tttctcaaga
     9181 ttttgaaggc atcttaaagg atgctcatga aattcgaaga caagcaggag atgatatatt
     9241 tatcaaagta cctgttactc cagctggatt acgtgcaata aaggtgctaa aaaaagaggg
     9301 ctaccatatc actgcaacag ctatttatac agttattcag ggattattag ctatcgaagt
     9361 aggagcggat tacctagctc catattataa tagaatggaa aatctgaaca ttgattcaaa
     9421 ttctgtcatt cgtcaattag ctcttgctat tgatagacag aactctccta gtaagatttt
     9481 agctgcatcc tttaaaaatg tagcacaagt aaataatgct ttagctgcag gtgcgcatgc
     9541 tgttacagca ggagcagatg tttttgaatc agctttcgcc atgccatcta tccaaaaggc
     9601 ggttgatgat ttttctgacg attggtttgt tactcaaaat agtcgttcca tttagataga
     9661 gaggaaatac atatgagaat ttttgctagt ccttctagat atattcaggg ggaaaatgcc
     9721 ttgtttgaaa atgccaaatc aattttggat ttgggaaatt acccgattct attatgcgat
     9781 cagttggttt atgatattgt tggaaaacga tttgaagatt atctacatag gtatggtttc
     9841 catattgttc tggcgctatt taatggtgaa gcttctgaca atgaaatcaa tcgagttgtt
     9901 gccttggctg agaaagaaaa ttgtgatagt attatcggtc ttggtggggg aaagacgatt
     9961 gatagcgcaa aagctattgc agatttgatt gaaaagcctg ttattattgc tccaacaatt
    10021 gcatcgaccg acgcacctgt atctgcttta tctgttattt atacagatga aggtgcattt
    10081 gatcattatc tattttattc taaaaatcca gatttagttt tggttgatac aaaagttatt
    10141 tcgcaagccc ctaagcgttt attagcgtct ggtattgcag atggtttagc aacttgggtt
    10201 gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt tgggacaaca gcaaacattg
    10261 gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt ttgcagatgg tttacaggct
    10321 atggcagctt gtgaagctaa agtggtgaca ccagcattag aaaatattgt tgaagctaat
    10381 actttattga gtggcctagg ttttgaaagt ggaggattag ctgcggcgca tgcaattcat
    10441 aatggtttta ctgcattgac aggcgacatt catcatttaa cacatggtga aaaagtagct
    10501 tatggaactt tagtacaact attattggaa aatagaccta aagaagaact tgataagtat
    10561 attgagtttt acaaaaaaat tggtatgcca acaactctaa aagaaatgca tttggatcaa
    10621 gttggatatg atgatttaat aaaagttggt aaacaagcaa ctatggaggg tgagacaatt
    10681 catcagatgc cgtttaagat ttcgccttca gatgttgctc aagctattat cgctgtagat
    10741 gcctatgtaa attcaaaata aacaataagg actactgttt tccaaatggt agtcttttat
    10801 tgatcctcgt attgaattct atagcagatt gaaataagat gagaacaaat cgat
//
LOCUS       DAVHSL010000066        10723 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000066 DAVHSL010000000
VERSION     DAVHSL010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.068"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(84..1508)
                     /locus_tag="VVR39_001905"
     CDS             complement(84..1508)
                     /locus_tag="VVR39_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6031316.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALSPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2053..4332)
                     /gene="pulA"
                     /locus_tag="VVR39_001906"
     CDS             complement(2053..4332)
                     /gene="pulA"
                     /locus_tag="VVR39_001906"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU6031317.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFSHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4444..6402)
                     /gene="ligA"
                     /locus_tag="VVR39_001907"
     CDS             complement(4444..6402)
                     /gene="ligA"
                     /locus_tag="VVR39_001907"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU6031318.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLTEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6495..7673)
                     /locus_tag="VVR39_001908"
     CDS             complement(6495..7673)
                     /locus_tag="VVR39_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6031319.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7753..8616)
                     /locus_tag="VVR39_001909"
     CDS             complement(7753..8616)
                     /locus_tag="VVR39_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6031320.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8619..10520)
                     /locus_tag="VVR39_001910"
     CDS             complement(8619..10520)
                     /locus_tag="VVR39_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6031321.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3207 a         2365 c         1909 g         3242 t
ORIGIN      
        1 accaaaaagt tcgtattttt tctataatta ttattttata gcaaaaaaat aaaaccagga
       61 aaacaatttc ctggttttac acgttatttc acatcaaaaa caatggattt gacatttgtc
      121 atcgcttcaa tgctatattt aattccttgc actccagctc cagaaccttt gacaccaagg
      181 aatgggaaat tatctggacc acgctgggtt ttattattaa tgtggactgt acctacttca
      241 agtttttcag caatttcaaa ggcttttttg aaatcatttg taaagactga tgattgaagg
      301 ccgaattcag attcgttggc aaaggcaata gcttcctcta cactagccac acgaatgatt
      361 ggtaaaacag gaccaaatgg ctcttcccat gccactttca tatcttttgt aacttggtca
      421 aaaagcactg gccagaggag attgccctca cgtttgattg gtgaaagagc ctgagcctct
      481 ttttcttgtg catcctcaat caagccccaa atgaagtcgg ctgaagcatt gtcaataaca
      541 ggtgtaatat cagcattgtc aaatggatca ccaactgtta atttagaaac ttcttcctga
      601 agcaaagtag ctaatttatc tgctacactt tcgagaacaa tgacacgttt aatggccgtg
      661 caacgttgtc ctgagtagct aaaggctccc gcaacaattt gcttggcagc atgttccaaa
      721 tctgcatctt ctagtacaag agctgcatct ttcccaccaa gttccaacat gataggacgc
      781 ataccagcta aacgaccaat acgttctcca ataggagttg aacctgtaaa gttgatgaag
      841 ttgacttctt tgtgctcaat gatataatcc ccaatttctg aaccacgacc tgtaatggtg
      901 ttgaaaacac ctgccggaat ccctgcttct tcaaatgctt tagccaacaa gagtccagaa
      961 atggaacctt gtgttggtgg cttaaacatg accacattcc ctgcaatcaa ggcaggtgca
     1021 attttagaag cagataaatt aactggataa ttaaaaggag caatcgctag cacgatacca
     1081 actggttcac gacggacaac agccagtttg tttttacttg ctgcctcaaa accaccacct
     1141 tccattgctt gtccagtgat acggagacct tcctcagcag cataacgaat caagtctgct
     1201 gtacgcacta cttctccaat tgctgcttta atcccttttg ctacttcttt ggcaaggata
     1261 gtaccaattt tttccttatc gcgttctaaa atagctgctg ttttatgcaa ataagccgca
     1321 cgttcaattg ctgataaagc tcgccatgct ggcagggctg cacgcgcagc ttgcatagcc
     1381 tcatcagctt cagtctgagt catggctgga actgtaccca attcttcttg attgattggt
     1441 gaataaatcg taatttcttg ttcagatgat ttccattttc catttactaa attctgatat
     1501 cttgtcaaat tcttgtcctc ctgaaaatga ttaagatata ttttaccaaa ttttcagaaa
     1561 atcacaaccc tttttgcgaa atttttgaga ttattttcac aatcttggtt tttcaaagta
     1621 tactcaataa aaattaaaaa aatccactac gtcaaggcga ggctaatgtg gtttgaagaa
     1681 attttcgaag agcgtgaatg agtatcatct atagtaaaat aaaaaaactg aacaatttgg
     1741 ttggggacag ccaaaccaat ttctcacaat gtttcagaaa caagggtgtg ctattccaat
     1801 ttcagcctac tataactgtc atagattgct gaaacaaagt ctaggtaaaa gtcttcataa
     1861 taaaaagacc ccctatcaag tgttcaaaaa ctttgatagg aggtcttgtt ttgtgaaaat
     1921 atttatcaaa ttttctatac aagtgagctg ttagccagat tctttctatt ctttcaattt
     1981 caatgaatgg attttttacc aatactcata actgggaatt tttctgtcta aaaatagcga
     2041 gatagatggt atttataaaa cactcaagac agctagacta atatcattta aaacattatc
     2101 ttcttttgag cgactgttgg ttaccaacat agctaaattt cctgcatttt caaattgata
     2161 gggttctgat ttagcattca caactaccaa gaggtgttct ttgccgtgaa cttcatagat
     2221 aaggcagccg ctatgttcaa tcgcagaatg cacaaagaca tgatggtaaa tttcatcata
     2281 gctagagtaa gaaaaggcac cagtttttgt cttcaatcgg atgacttgac ggataaactc
     2341 aatactgtct tgacgctcat taatcaagtt ccagttcact tggttcacac tgtcaggagc
     2401 attatagcta ttcatcgcac gctctctatc atcatgggtc aactcaccat tttcaccagt
     2461 cgcaaccagt ttggtacgac caaattcttg accgatttcc ataaaggcca tcccctgcat
     2521 gagcagattc atggctgtgg cagtttcgac cttgcgcatg atttgctctg aactttggtc
     2581 tggatgaagg gttgccaata aatcgtgaag attgtaattg tcatgggctt ctacatagtt
     2641 aagcacctga tttggatgtg tatagcttcc taattcacga cttcctagga ttgctttagc
     2701 tagaattggc tctgtcgcag caccactgac aaaacctgac ttgatagcac cataaacttc
     2761 tccccctttg acagcatcgc gctgattgtc attaaagaaa ccaatatttg gcatctggta
     2821 ggcattgtcc ttcttggcct tatcataagg ggcaagacct gttcccatat cccatccttc
     2881 tccatagagg ataatgttgg agtcgatttc atccaagctt tgacgaatca tctgcatggt
     2941 cttgacatca tgaatcccca tcaagtcaaa acggaagccg tcaatattat attcctgcac
     3001 ccagtataga agagaatcaa tcatatactt gcgaaacatt tcgtgttcac tggctgtttc
     3061 atttccaaca cccgttccat tctggaaggt accatctgga ttcatacgat aatagtaatc
     3121 agggactgtt gtttggaatg gtgcatcaac aactgagaag gtatggttat agactacatc
     3181 cataatgact ccaatacccg catcgtgata agcttgaacc atcaccttca aatcacgaat
     3241 gacctgagct ggatcatctg gattagttga aaaactagtt tctggcgcgt tatagttttg
     3301 tggatcataa ccccagttgt aggttacatt tccatcctca tcgtattctt tatgacggtc
     3361 tgcaattggt tgcaattgaa cataattgta gcccagcttc ttgatgtaat caaaagcagt
     3421 tgactggccg tattggttaa ctgttccagc ctgagcagca cccaagaaag ttcctcgaag
     3481 atgttcatct acacccgatg taggtgattt agtcaaatca cgaatgtgca tttcacagat
     3541 aactgcctta catggatttt ccaagcgcca agtagcctcc gaaccgtgct taacctcgaa
     3601 gttttcaact tgcttttcta catggctcag aatagctgaa cgtttgccat cagggctggt
     3661 cgcgattgta taaggatcac gtgtcagtgt ttggtgatga gagaattgga cttgatactg
     3721 ataagtctta cctaccaaat cttcttcaac atccaaactc catacaccga ttgtattgtc
     3781 cttatgatta taagagtagc tattgcctct tttcatctca aaagtcttcc aaacgggtgc
     3841 atcattagca gctgattcat aaacgacaac ttgtacttct gtcgctgtag gtgaccagag
     3901 ggaaaaatga gcctgattgt cctctacacg gcaacccaat tctccttggt aaccccaatg
     3961 atgatcaaaa ctagcactgt taatggcctt atcaaaggca aaaggatttt gatttttata
     4021 gaaaggactg gcaatagcag gattttcaga gtaataaatc ctatcatcgc cttccaaaat
     4081 ccagacctct gttaataggg gatagtgatt aaaacggata gaatattctt tactagtttg
     4141 acctgtatga accacaaaat tcaagctttc tataacatgt gaacttgggt gttcaaagct
     4201 aaataaagct ccaaaataat cttctttgta ggttagcaaa tcaattcgtt gatcctgact
     4261 ttttacaaag gagcaagtgt catattctcc attcttacga tggtaatgaa tgcgcatagg
     4321 gtagttatac attttttatt tttccttttt actttgtttc tatttcacta ataaattttt
     4381 gtcaatctcg tctcaattaa cagacatagt catattctct aaactctgtt tttaaacgat
     4441 ccattacaaa ctttctagcc atgcctcatc tctgacctgg ataccaagtt cttgtgcttt
     4501 ttgcagttta cttccagcgt ctgcacctac cacgacgagg tcggtctttt tagaaacact
     4561 acctgtcact ttggcaccca gactttcgag tttactttta gcttctgagc gcttgagtcg
     4621 ttccaatttt cctgtcaata ccacggtcaa acctgacaag gccgcatccg ctactaccgt
     4681 ctgtccttta tagtccagat tgaccccagt ttctttcaat tctctgagca gaatttcaga
     4741 gccttctgtc gcaaaataag tctgaagact tttggcaatc acgccaccta gactttcaat
     4801 actagccact tcctctgaat ctgcctgata cagattttca attgaatgga aatattgaag
     4861 taaaagctga ctagccttgc ttccgacatg acgaattccc aaaccaaata agagcttctc
     4921 ggcagaattt tcctttgatg cttggatagc ctgatacagt ttagcagcgg acttttcctt
     4981 aaccccctct aaaaggagga aatcctcttc ttgcaaacga taaatatccg ccacatcctt
     5041 gactaaatta gcagcaaaaa gcttctcaac aatagatgga ccaaggcctg taatattcat
     5101 agcatcacga gaagcaaagt gaatcaagcc ttccatgatt tgagcagggc aacgcggatt
     5161 gatacaacgt agggccactt catcttcaaa gtgcaacaag tcagagttac aacttggaca
     5221 gtttgtaggg atatctagtt tttcttcaga gacccgtttg gactctacca cacgtaaaac
     5281 ggcagggatg atgtcaccag ccttatatac aatgaccgta tcgtcttttc ggatatcttt
     5341 ttcagcaata taatctacat tgtgcagggt cgcacggcta acagtcgtac cggcaagttg
     5401 tactggtgtt agattagcag ttggagttac aacaccggta cggccaactg tccagtcaac
     5461 tgataagagt tgagcttctt tttcttcagc agggaacttg taggctactg cccactttgg
     5521 agccttaacg gtaaaaccaa gttcttcttg acttgctagg tcgttgacct tgattaccac
     5581 tccatcaata tcgtaaggca gattttcccg ttcctgtcct acttcttgga taaaattcca
     5641 gatttcatct atgttttcag ccaagattcg cttaggattg accacaaaac ctagttgttc
     5701 taggtacttc aaaccctttt cttggctatc acgagttgaa gggctggctt cttgatagag
     5761 aaacgttgcg agattacgct tggcaactac tgctgtatcc aactgacgca gagttcctgc
     5821 tgccgcatta cgaggattag caaattcagg ctctccattt tcttggcgcg cttggttaac
     5881 ttggtcaaag gaagcgcgtg gcatgtaaca ttccccacga actgtgatat ctagttcttc
     5941 tgtcaaagtc aaagggatgt ccttaacacg cttgaggttt tctgtgatat tttcaccaat
     6001 tgaaccatct ccacgtgtta ccccagcaac caaaatcccc ttttcataag tcagcgagat
     6061 agataagcca tcgattttca gctcacaaat ataggtcgga tgagccactt ccttacgaac
     6121 acgcgcatca aaagcatcta gctcctcacg tgaaaaagca tcctgcaaac tataaagagg
     6181 atactgatga ctgtattttt caaaaccatc taaaaccttg ccaccaacac gatgagtcgg
     6241 actgtctgct agcacttgct ctggataagc agtttctaac tcgaccaact cacggtaaag
     6301 gcggtcatac tcactgtctg aaaccgaggg attatcgctg gtatagtact cagtcgcata
     6361 gcgattgagc aaagcgacta actcattcat tcttttattc ataagaccat tttaccataa
     6421 aacaagccct cctcacaaac gagaagggcg gaaaaaacac ttagtttgaa attatttttg
     6481 aaactcaagc aaccttatat caatttttca aaatgagttc gaacataaat aaacgatata
     6541 caagacaaga tgataacacc acttccaatt atcaggaaag aagagagatg tacacttggc
     6601 aagactgtca taaatccttt tgcaataggc ataaatagaa tagctaaggt aaaaattgta
     6661 ctcagtactc tcccaagaaa ttcgctctca accttggttt gtacttgagt aaaaaagtga
     6721 atattaaaaa tcgtcataaa caattcacaa actaaatttc cagaaaagga aagaaaagtt
     6781 ggaagtggta atcccatcat aaaaactccg acacctgtca aagccagtaa aatcaaaaga
     6841 ttataaatat tagctttaat tttactagct agaagagccc caatgatgga accaatagcc
     6901 cccatagtta aaatacttgc ataggctcct tctgacccgt aaagctgatt cgaaaaggga
     6961 agtagaaatt caaaagctgc aaaaaagaaa ttaacgctgg aagctaccag caaaaggaag
     7021 aaaatttctt gctgatgcca gatatagtgt aacccatcct tgatatctac aaaaatatct
     7081 ctcccagtaa aagccttttt ctcttgaact tttgcttcct cttttggaag gaaagccact
     7141 agaacaaaag caatgaaaaa agtcagcgag tctagcagta gcgtcatatg gagacttgca
     7201 aactgtaaaa caaggaagga aagaacagga gagctaacac ctacaacctg caaaaccagc
     7261 tctaagcgag aattatagat cacaatctca tctttctcca ccacttcagt tatgatagct
     7321 ttattggctg tgcgagaaaa ggcaaaagca atagcctgca caatgttagc aacaatcaaa
     7381 gcgccaatca tccagctatc attccttatg aaagaaatag ccagacaaag aatcccacaa
     7441 acaagatctg ccgtcattaa aatcttacga cgagaaaaac ggtctgaaat aactccgcca
     7501 aagggattga cgagaataga tgtgacgagc tcagaaatct gatacattcc taaaactgtc
     7561 tgtcctatag tccccataga agccaaccag acactatttc cataatcata gagcatattt
     7621 cccattttat tgatagcccc acggctaatc aactgcactg catagcgatt catattaaag
     7681 ctcctctcaa attttgaaac tattgtatca aaaccgaaag gagcttttta ttttttccct
     7741 tatttgggaa aattaacttt tgacaaattt ttcgtagtgt tcctgataat aggctacttg
     7801 ctctggaaga cctaacacat caaaaatatg catggcctct tgcatctgct tacagccttc
     7861 tttacactgt cctttttgat ataaggccaa accttttaaa taatggaaaa cattacgctc
     7921 ataaagctta atacctttgt caataatctt ctctgtataa gcctcaaaat agttggcatt
     7981 ataaaaagaa gaatgctcta aacaatgctg gtaacaattg agggccaaaa ttaacactaa
     8041 tctcttatgg cgactaatct cttggtaaaa ttcctccctc tccataactt ctctaccaat
     8101 ccgagtgaca tagtctacat cgtagaaact atagaggtta ccgaaaagaa tcaactcata
     8161 catggtccat tcttctgttt tgaagagata atctgctacc ttatccaaat catcctgctt
     8221 catatcataa ctcgcatctc tttgacaaat cagaccttgt agcaaaatcc agttcagctc
     8281 aaaataaagg gaagtcgtcg aactcttaga cttttcaagt tgttctcttt gaagcttttg
     8341 aaaacctgca atatcgtttg aatagtaaag tgggataatc tgtgccatca tagacacatg
     8401 ttcatgatta tgaaaattcc ttgccttatc catgaaattt tcgattgtta catgaatgtt
     8461 atccaaaatc tcaaagaaac gggagactgc caggtcagac tccccaagct caaagcgaga
     8521 taactgagag gtagagcagg attcgcctgc tgcttccttt aaagaataat ttccacttgt
     8581 tcgaaattca cgaaatactt ttccaagatg ttccatcttt acacctgatc tgataattct
     8641 tcccactcaa gcatagcttc ttcctgacga tggctgattt tatccagctc agcctgtaat
     8701 tccatgagtt tgtcggcatc gtttgtttcc aacatttgtt cagaaatggc ttggctttga
     8761 ctttctagct cttcaatttc agcttctaga ctttcgattt gtcgcatgag tttgcgaact
     8821 tctttttgac tttctttctg ggcctgatag tcattgactg gacttgcttc ctttgcttga
     8881 ttgctagttg aagcttcctc agtctgactc atttctgctg ttgctttctt ctcaacatag
     8941 tagtcgtaat ctccaaggta gagagttgaa ccattctcag acaattccaa aacatgagtt
     9001 gccacacaat tgataaagta acgatcatga ctgacaaaca gcaaggtacc atcaaagtca
     9061 atcaaggcat tttctagcac ttccttacta tcaatatcca agtggttggt cggctcatcc
     9121 agaatcaaaa agttattgtt ttccatagac aatttagcta aaagcaaacg agctttttcg
     9181 ccaccagata gcatgccgac tgatttttta acatcatctc ctgagaaaag gaaggctcca
     9241 agacggttgc ggatttcaac ttctggtgtc agtttgaaat cattccagag ttcatccagc
     9301 accgtattac ttggtgtcag cttgctttgg gtttggtcat agtaaccaac ctcaacatta
     9361 gcgccaaagc gcttttctcc cttgataaac ggaatttgat ccacgattga tttgataaag
     9421 gttgattttc cgataccatt gggaccaacg atagcaacag cattcatctt acgaaggtct
     9481 aggttaatcg gttgtgacag gacttcccca tcatagccaa cagccgcatt ttcaacagtc
     9541 aaaacaacat tgcccgacgt tttttcagac tggaaggtca tgttggctgc tttcttgcca
     9601 gcttccggct tgtccaaacg ctccattttt tctagttgtt tacggcgaga ttgagcacgt
     9661 ttggtcgttg aagcacgaac tagattgcga ttgacaaagt cttccagagc agcgatttcc
     9721 ttctgttgct tttcatagtt ttttgcctca gtagctagct tttgctcctt caactcgaca
     9781 aaacgagagt aattccccac atagcgatcc aaggaatgct tggtcaaatc tagcgtaatt
     9841 gtcgcaacct tgtccaagaa ataacggtcg tggctgacga taatgagggc tccgctatag
     9901 tttaccaagt aattctctag ccaggagatg gtttcaatat ccaagtggtt agttggctcg
     9961 tccaagacca agagattggg cttttcaagg agcattttag ctagagccaa acgagtattt
    10021 tgaccacctg aaagttcagc tattttcatc tgccacatag actcgtcaaa cttgaatcca
    10081 ttcaaaatcg ctcgaatatc agcttcatag gtaaagccgc ctgcttggcg aaaattctca
    10141 gataagtggt cgtaatctga catcagttta tccaattcat cgccagactt ttcacccatc
    10201 tccaactcca tctgacgaag ttgtttatct gtccgacgta agtcatcaaa gacatgaagc
    10261 atttcatcgt agatggtatt ttcagactca aaacggctat cttgggctag gtaagacaga
    10321 gaaatatctt ttttcttatt gatttctccg ctagttggct cctcttctcc aactaaaatc
    10381 ttcaaaagag tagacttacc tgcaccattt ttcccaacaa gagcaatccg atctcgttca
    10441 tcaacctgca ggttgatatt atcgaaaaga acctctcctg caaaagaacg ttcaatttta
    10501 ttagcttgta aaataatcat acaagtagta tagcatgttt ccctaagtca ttcaagataa
    10561 tcgtaagtct tttagtacaa cttttataac ataaaataaa ctaaattatg tatattttat
    10621 attagattcc ttcactatct tgttggattt tctaaccagc taatcttgtt tcaaatagtt
    10681 atcgcacaag tctattattt aattcttttc attatttacg tac
//
LOCUS       DAVHSL010000067        10657 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000067 DAVHSL010000000
VERSION     DAVHSL010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.069"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..610
                     /locus_tag="VVR39_001911"
     CDS             <1..610
                     /locus_tag="VVR39_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU6031322.1"
                     /translation="SKQDLLYPRKGKALKKQASTNFKPAGQSIEQRPEAINLRLENGH
                     YEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITA
                     DNGTEFNRLSNVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFI
                     EKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
     gene            685..885
                     /locus_tag="VVR39_001912"
     CDS             685..885
                     /locus_tag="VVR39_001912"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU6031323.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            920..1636
                     /gene="atpB"
                     /locus_tag="VVR39_001913"
     CDS             920..1636
                     /gene="atpB"
                     /locus_tag="VVR39_001913"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU6031324.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            1650..2144
                     /gene="atpF"
                     /locus_tag="VVR39_001914"
     CDS             1650..2144
                     /gene="atpF"
                     /locus_tag="VVR39_001914"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU6031325.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            2144..2680
                     /locus_tag="VVR39_001915"
     CDS             2144..2680
                     /locus_tag="VVR39_001915"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU6031326.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            2695..4200
                     /locus_tag="VVR39_001916"
     CDS             2695..4200
                     /locus_tag="VVR39_001916"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU6031327.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            4216..5094
                     /locus_tag="VVR39_001917"
     CDS             4216..5094
                     /locus_tag="VVR39_001917"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU6031328.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            5180..6586
                     /gene="atpD"
                     /locus_tag="VVR39_001918"
     CDS             5180..6586
                     /gene="atpD"
                     /locus_tag="VVR39_001918"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU6031329.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            6597..7016
                     /locus_tag="VVR39_001919"
     CDS             6597..7016
                     /locus_tag="VVR39_001919"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU6031330.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(7061..8074)
                     /locus_tag="VVR39_001920"
     CDS             complement(7061..8074)
                     /locus_tag="VVR39_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU6031331.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            8218..9384
                     /locus_tag="VVR39_001921"
     CDS             8218..9384
                     /locus_tag="VVR39_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6031332.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9374..10603
                     /locus_tag="VVR39_001922"
     CDS             9374..10603
                     /locus_tag="VVR39_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU6031333.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISHDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
BASE COUNT         3132 a         1957 c         2354 g         3214 t
ORIGIN      
        1 aagcaagcag gatctgcttt accctagaaa aggaaaagcg cttaagaaac aggccagcac
       61 caactttaaa cctgctggtc aatccatcga acagcggcct gaagctatca atcttcgctt
      121 ggagaatggg cattatgaga ttgatacggt tctacttacg agagcgaaaa actactgctt
      181 gcttgtcttg acggatcgaa aaagtagaca tcagatcatc cgattgattc caaataaaag
      241 tgctgaggtg gtcaatcagg ctctaaaact catcttaaaa caacacaaga ttctttccat
      301 cacggcagat aatggaacgg aattcaatcg cttgtctaat gtattttctg aggagcacat
      361 ttattatgca catccctatg cctcttggga aaggggaact aatgagaatc acaacaggct
      421 cattcgtaga tggttaccta agggaaccaa gaaaatgact cccaaagaag tcgcattcat
      481 cgaaaagtgg attaacaact atcctaaaaa atgcttggac tacaagtcac ccagagaaga
      541 cttctggatg gctaacttga acttgaaatt tagcaaaatg gaaataattt ttattaaacg
      601 cttccaatag cggttaaaag ttgacaaatt taaattttag gactacacta agtaagtaaa
      661 ttttatttta aaggagaatt tgttatgaat ttaacatttt taggcttatg tattgcctgt
      721 atgggcgtat ctgtcggtga aggtttattg atgaatggac tgtttaaatc agtagcacgc
      781 caaccagata tgctttctga gtttcgtagt ttgatgtttt taggtgttgc ctttattgaa
      841 ggaactttct ttgtaactct tgtcttctca tttattatca aataaataca tggaacgaga
      901 agaaaaggga ggattttaga tggaagaaag tattaatcca atcatctcta ttggtcctgt
      961 tatcttcaat ctgactatgt tagccatgac tttgttgatt gtgggagtta tttttgtctt
     1021 tatttattgg gcaagccgca atatgacctt gaaacccaaa ggaaagcaaa atgtacttga
     1081 gtatgtctat gactttgtta ttggatttac agaacctaac attggttcgc gctacatgaa
     1141 agattactca ctctttttcc tttgtttatt ccttttcatg gtgattgcca ataaccttgg
     1201 cttaatgaca aagattcaaa cgatcgatgg gactaactgg tggagttcgc caaccgctaa
     1261 tttacagtat gacttaacct tatcttttct tgtcattttg ttgacacata tagaaagcgt
     1321 tcgtcgtcgt ggatttaaaa aaagtataaa atcttttatg agtcctgttt ttgtcatacc
     1381 gatgaatatc ttggaagaat ttacaaactt cttatctttg gctttgcgga tttttgggaa
     1441 tatctttgca ggagaggtca tgacgagttt gttacttctt ctttcccacc aagctattta
     1501 ttggtatcca gtagcctttg gagctaattt ggcttggact gcattttctg tctttatttc
     1561 ctgcatccaa gcttatgttt ttactctttt gacatctgtg tatttaggga ataagattaa
     1621 tattgaagag gaatagaaag gagtaactga tgcacgtaac agtaggtgaa ttaattggta
     1681 attttatttt aatcactggc tcttttattc ttttgctagt cttgattaaa aaatttgcat
     1741 ggtctaatat tacaggcatt ttcgaagaaa gagctgaaaa aattgcttca gatattgaca
     1801 gagctgaaga agcccgtcaa aaagcagaag tattggctca aaaacgcgaa gatgaattgg
     1861 ctggtagccg taaagaagct aagacaatca ttgaaaatgc aaaggaaaca gctgagcaaa
     1921 gtaaggctaa tatcttagca gatgctaaac tagaagcagg acacttaaaa gaaaaagcca
     1981 atcaagaaat tgctcaaaat aaagtagaag ctttacagag tgttaagggt gaggtcgcag
     2041 atttgaccat cagcttagct ggtaaaatca tctcacaaaa ccttgacagt catgcccata
     2101 aagcactcat tgatcagtat atcgatcagc taggagaagc ttaatggaca agaaaacagt
     2161 aaaggtaatt gaaaaataca gcatgccttt tgtccaattg gtacttgaaa aaggagaaga
     2221 agaccgtatc ttttcagact tgactcaaat caagcaagtt gttgaaaaaa caggtctgcc
     2281 ttctttttta aaacaagtgg cagtagacga gtcggataag gaaaaaacaa ttgctttttt
     2341 ccaagattct gtgtcgcctt tattacaaaa ctttatccag gttctggcct acaatcacag
     2401 agcaaatctt ttttatgatg tgcttgtaga ttgcttgaac cgacttgaaa aagaaacaaa
     2461 tcgatttgaa gtgacgatta cgtctgctca tcctctaact gatgaacaga agactcgttt
     2521 gctccctttg attgagaaaa aaatgtctct gaaagtaagg agtgtaaaag aacaaatcga
     2581 tgaaagtctc attggtggtt ttgtcatttt tgccaatcac aagacaattg atgtgagtat
     2641 taaacaacaa cttaaagttg ttaaagaaaa tttgaaatag aaagtggtgt tcttttggca
     2701 attaacgcac aagaaatcag cgctttaatt aagcaacaaa ttgaaaattt caaacccaat
     2761 tttgatgtga ctgaaacagg tgttgtaacc tatatcgggg acggtatcgc gcgtgctcat
     2821 ggccttgaaa atgtcatgag tggagagttg ttgaattttg aaaacggctc ttatggtatg
     2881 gctcaaaact tggagtcaac agacgttggt attatcatcc taggtgactt tacagatatc
     2941 cgtgaaggcg atacaatccg ccgtacaggg aaaatcatgg aagtccctgt aggtgaaagt
     3001 ctgattggtc gtgttgtgga tccgcttggt cgtccagttg acggtcttgg agaaatccac
     3061 actgataaaa ctcgtccagt agaagcacca gctcctggtg ttatgcaacg taagtctgtt
     3121 tcagaaccat tgcaaactgg tttgaaagct attgacgccc ttgtaccgat tggtcgtggt
     3181 caacgtgagt tgattatcgg tgaccgtcag acagggaaaa caaccattgc gattgataca
     3241 atcttgaacc aaaaagatca agatatgatc tgtatctacg tcgcgattgg acaaaaagaa
     3301 tcaacagttc gtacgcaagt agaaacactt cgtcagtacg gtgccttgga ctacacaatc
     3361 gttgtgacag cctctgcttc acaaccatct ccattgctct tcctagctcc ttatactggg
     3421 gttgctatgg cggaagaatt tatgtatcaa ggtaagcatg ttttgattgt atacgatgat
     3481 ctatcaaaac aagcggtagc ttatcgtgaa ctatcgctct tgcttcgtcg tcctccaggt
     3541 cgtgaagcct tcccagggga tgttttctat ctccacagcc gtttgcttga gcgctcagct
     3601 aaagtttctg atgaacttgg tggtggatca attacagccc taccatttat cgagacacaa
     3661 gcaggagata tctcagccta tatcgcaacc aacgtgattt ctatcactga tggacaaatc
     3721 ttccttggcg atggcctctt caatgcaggt attcgtccag ccatcgatgc gggttcatct
     3781 gtatctcgtg taggtggttc tgcacaaatc aaagccatga agaaggttgc tggtacactt
     3841 cgtatcgacc ttgcttcata ccgtgagtta gaagccttta ctaagtttgg ttctgacttg
     3901 gacgcagcaa cacaggctaa gttgaaccgt ggacgtcgta ccgttgaggt cttgaaacaa
     3961 cctgttcaca aaccattacc tgttgagaaa caagtaacca ttctttatgc tttgacacat
     4021 ggtttcttgg atactgttcc agtagatgat attgttcgtt tcgaggaaga gttccatgcc
     4081 ttctttgatg ctcaacatcc agagattttg gaaaccattc gtgatacaaa agacttgcca
     4141 gaagaagcag tcttggatgc tgcgattaca gagtttctca atcaatctag cttccaataa
     4201 gaatagaggt gtcagatggc agtgtctcta aatgatatta aaacaaaaat cgcctcaaca
     4261 aaaaatacga gtcaaatcac taatgccatg caaatggtat cggctgctaa gctaggtcgc
     4321 tctgaagaag ctgctcgcaa cttccaagtt tacgctcaga aagtgcgtaa acttttgaca
     4381 gatatccttc atggtaatgg agctggtgct tcaactaatc cgatgttgat tagccgttct
     4441 gtgaagaaga caggctatat cgttatcact tcagaccgcg gtttggttgg aggttataat
     4501 tcctctattt tgaaagctgt tatggagttg aaagaagaat accacccaga cggtaaaggt
     4561 tttgaaatga tctgtatcgg tgggatggga gctgatttct ttaaggctcg cggtattcaa
     4621 ccactttatg aattacgtgg cttggcagac caacctagct ttgatcaagt tcgtaagatt
     4681 atttcaaaaa ctgttgaaat gtaccaaaat gaactctttg atgagcttta tgtttgctac
     4741 aaccaccatg tcaatacgct aaccagtcaa atgcgtgtgg aacaaatgct tccgattgtt
     4801 gacttggatc caaatgaagc ggatgaagag tacagcttga cttttgaatt ggaaaccagc
     4861 cgagaagaaa ttctggagca gttgttgcct cagtttgcag aaagtatgat ttacggtgcc
     4921 attatcgatg ccaagacagc tgagaatgct gcgggtatga cagccatgca aacagcgaca
     4981 gataatgcta agaaagtcat caatgatttg acaattcagt ataaccgtgc cagacaggcg
     5041 gcgattacac aagaaattac agaaatcgta gcaggtgcta gtgccttaga ataggctcta
     5101 gtccagctcg tatgaaaatg aacttaggac ctagttgagc taggaaccga cagtatctta
     5161 tatagaatag gagaaggaga tgagttcagg taaaattgct caggttatcg gtcccgttgt
     5221 agacgttttg tttgcagcag gggaaaaact tcctgagatt aacaatgcac ttgtcgtcta
     5281 caaaaatgac gaaagaaaaa caaaaatcgt ccttgaagta gccttggagt taggagatgg
     5341 tatggttcgt actatcgcca tggaatcaac agatgggttg actcgtggaa tggaagtatt
     5401 ggacacaggt cgtccaatct ctgtaccagt aggtaaagaa actttgggac gtgtcttcaa
     5461 cgttttggga gataccattg atttggaagc tccttttaca gaagacgcag agcgtcagcc
     5521 aattcataaa aaagctccaa cttttgatga gttgtctacc tcttctgaaa tccttgaaac
     5581 agggatcaag gttattgacc ttcttgcccc ttaccttaaa ggtggtaaag ttggactttt
     5641 cggtggtgcc ggagttggta aaaccgtctt aatccaagaa ttgattcaca acattgccca
     5701 agagcacggt ggtatttcag tatttactgg tgttggggaa cgtactcgtg aggggaatga
     5761 cctttactgg gaaatgaaag aatcaggcgt tatcgagaaa acagccatgg tctttggtca
     5821 gatgaatgag ccaccaggag cacgtatgcg tgttgccctt actggtttga caatcgctga
     5881 atacttccgt gatgtggaag gccaagacgt gcttctcttt atcgataata tcttccgttt
     5941 cactcaggct ggttcagaag tatctgccct tttgggtcgt atgccatcag ccgttggtta
     6001 ccaaccaaca cttgctacgg aaatgggtca attgcaagaa cgtatcacat caaccaagaa
     6061 gggttctgta acctctatcc aggctatcta tgtgccagcg gatgactata ctgacccagc
     6121 gccagcaaca gccttcgctc acttggattc aacaacaaac ttggaacgta aattggtaca
     6181 attgggtatc tacccagccg ttgacccact tgcttcaagc tcacgtgcct tggcacctga
     6241 aatcgttgga gaagagcact atgcagttgc tgctgaagta aaacgtgtcc ttcaacgtta
     6301 ccatgaattg caagatatca ttgctatcct tggtatggat gagctttctg atgaagaaaa
     6361 gaccttggtt gctcgcgccc gtcgtatcca gttcttcttg tcacaaaact tcaacgttgc
     6421 ggaacaattt actggtcagc caggttctta tgttccagtt gctgaaactg tacgtggctt
     6481 taaggaaatc cttgatggta aatacgacca cttgccagaa gatgccttcc gtggtgtagg
     6541 ttctatcgaa gatgtgattg caaaagctga aaaaatggga ttttaagagg tgacctatgg
     6601 ctcagttaac tgtccagatc gtgacaccag atggtctcgt ctatgatcac catgccagct
     6661 atgtatcggt tcgaactctg gatggtgaga tggggatctt gccacgacat gaaaatatga
     6721 ttgcggtttt agcagttgat gaagtaaagg taaaacgtat cgatgataaa gatcacgtga
     6781 actggattgc agtaaacggt ggcgttattg aaattgccaa tgatatgatc acaatcgtcg
     6841 ctgactctgc agaacgtgct cgtgatatcg atattagccg tgcagaacgt gccaaacttc
     6901 gtgcagaacg tgcaattgaa gaagcacaag acaaacattt gattgaccaa gaacgtcgtg
     6961 ctaagattgc tttgcaacgt gccattaacc gtattaatgt cggaaataga ctataagaaa
     7021 aaatgaactt gaaaatacca agttcatttt ttatggtgtt ttaaggagca aaacggatgc
     7081 agactgcttc gggaacatgg aagtcgttgg agagttctgc tagacgacca ttgtcacaat
     7141 tacgtttaaa gacagttgca ttgtcagagt cttgatggac aacaatgaga aatttttggt
     7201 cgggtgtcaa atcaaaatca cgtggagtct gaccatgcgt tggaacgatt tctaataact
     7261 ctaagctacc gtccgcaagg atggtatata ctgcgataga atcatggcca cggttagaag
     7321 cgtagaggta tttaccgtct ttagagagat gaatagcagc ggttccatta aagccttcgt
     7381 aagcttctgg taaagttgaa ataacctgca tacgttcaaa ttcgccaacg ccatcgtaga
     7441 ttaaaacttc gatagtacta ttgagttcac aaatgagata agcgatttta tagtggttat
     7501 ggaaaatgat atggcgtgag cctgctcctg gcttgctgtg ataggtatag agcttagata
     7561 attttccttc ttgatcgagg tcataggtga tgacttggtc agttcccaag tcgcaggtca
     7621 ctagatagtg gtcaggtgtt aaatctgtat agtgaacatg gggggaagct tgattttcat
     7681 gtggaccttg gccactgtgt tgatccatat cactaagtag aagactacca tcttcctggc
     7741 gtttataaac aaggacttgt cccttgtgat agttggctgc gtaaaccaaa tcacgctttt
     7801 catcgacagc aacataacag tggggagctc cttcttcaac aacatgattt aacacagtcc
     7861 cgtcagtttg ataggctgca attcccccct tatcgtcttg gctaccaaca gtgtataaat
     7921 gttggtgctg gtcaaaggca aggtaggttg gacttggctc agctgcaaaa agttctagat
     7981 ttgaaagctg accagtttct gtatcaaagt ctgccttgta aatcccttga gaagtacgac
     8041 gtgtataagt tccaaaataa acagtttctt tcattactat acctctgtgt aaagataaga
     8101 ctattatatc acaaaaacaa gtaaattaaa gatatccaat tagatgtaag cactttaaaa
     8161 aagagttatt ttgtttcaaa aatggtataa tgagagaaca atagaaagga agtatttatg
     8221 gagcaaaaag agaaacattt tagcctatct tggtttttca agtggttttt agataacaag
     8281 gcaattacgg tatttttagt aaccttatta ttgggactga atctttttat tttaagtaag
     8341 attagttttc tattttcacc tgttttagac tttttagcag ttgtgatgtt gccagtcatt
     8401 ttgtctggtt tgttatatta tttgttgaat cctattgttg attggatgga gaagcataag
     8461 gttaatcgtg ttatagctat cactattgtc tttgttatca tcgctctctt tatcatttgg
     8521 ggcttggcag tcgccattcc aaatctgcaa cgtcaggttt tgacctttgc aagaaacgtt
     8581 cctgtttact tagaagatat agataggatt gttaatggat tggtagccca gcacctgcca
     8641 gatgatttca gacctcaatt agagcaagtt ttgaccaatt tttctagcca ggctacagtt
     8701 ttggcaagta aggtttcatc tcaggcagtc aactgggtga gtgcctttat tagcggagct
     8761 tctcaagtga ttgttgcctt gattatcgtt cctttcatgc tcttttatct cttgcgtgat
     8821 gggaaaggct tgcgtaacta tttgacccaa ttcattccaa gaaaattgaa ggaacctgtt
     8881 ggacaagttc tatcagatgt gaatcaacag ttgtccaact atgttcgagg gcaagtgaca
     8941 gtggctatta ttgtagcagt aatgtttatc atcttcttca agattattgg tctacgctat
     9001 gcggttacgc tgggggttac tgctggtatt ttaaatctgg tcccttatct tggtagcttt
     9061 ctagccatgc ttcctgctct agtattgggt ttgattgctg gtccagtcat gcttttgaaa
     9121 gtagtgattg tctttatcgt agaacaaact attgaaggcc gttttgtctc tccattgatt
     9181 ttgggaagtc aattaaacat ccatcctatt aatgttctct ttgttttgtt aacttcagga
     9241 tctatgtttg gtatctgggg agttttactt ggtattccgg tttatgcctc tgctaaggtt
     9301 gtcatttcag ccattttcga atggtataag gtagtcagtg gtctatatga attagagggt
     9361 gaggaagtca agagtgaaca atagtcaaca gatgttacag gctttggagg agcaagattt
     9421 aactaaggct gagcattatt tcgccaaagc tttagaaaat gattcaagtg atcttctgta
     9481 tgagttggca acttatcttg aagggattgg tttctatcct caggccaagg aaatttacct
     9541 gaaaattgta gaggattttc cagaggttca tcttaatcta gctgcaattg ctagcgagga
     9601 tggtcaaata gaagaagcct ttacctatct tgaggaaatc caagctgaca gtgactggta
     9661 tgtctcgtct ttggctctga aggcagacct ttaccagctg gaaggtttga cagatgtggc
     9721 acgtgagaaa ttattggagg ccttgaccta ctcagaggat tctctcttga tattgggttt
     9781 ggcagagttg gatagtgagt tggaaaatta ccaagcggct attcaagcct atgcccagtt
     9841 agataatcgc tcgatttatg agcaaacggg catttccacc tatcaacgaa ttggctttgc
     9901 ctatgctcag ttagggaaat ttgaaacggc tactgagttt ttagaaaaag ccctggagtt
     9961 agaatacgat gacttaacag cttttgagtt ggccagtctt tattttgatc aagaagaata
    10021 tcaaaaagcc accctctact ttaagcagct tgataccatt tctcatgact ttgaaggcta
    10081 tgagtatggg tacagtcagg ctttacataa ggaacatcaa gttcaagaag ccctgcgtat
    10141 cgctaagcaa ggattagaga aaaatccctt tgaaactcgc ctcttgctag ctgcttcaca
    10201 attttcttat gaattgcatg atgctagtgg tgcagaaaat tatcttcttg ctgcaaaaga
    10261 agacgctgag gatacagaag aaatcttgct tcgtttagcc actatttatc tggagcagga
    10321 gcgttatgag gatattctag acttgcagag tgaggagcca gaaaatcttt tgaccaagtg
    10381 gatgattgct cgttcttatc aagaaatgga cgatttggat actgcttatg agcattatca
    10441 agagttgaca ggagatttga aggacaatcc agaatttctg gaacactata tctatctctt
    10501 gcgtgaattg ggacattttg aagaagcaaa agtccatgct cacacttact taaaactggt
    10561 tccagatgat gtgcaaatgc aagaactgtt tgagagattg taagaatgtt taaacatata
    10621 gaactgtagt ttatctcttt tgatagctac ggttttt
//
LOCUS       DAVHSL010000068        10577 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000068 DAVHSL010000000
VERSION     DAVHSL010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.070"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..551
                     /locus_tag="VVR39_001923"
     CDS             <1..551
                     /locus_tag="VVR39_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6031334.1"
                     /translation="KCDGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSP
                     VLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYRHDSYHRFL
                     ESKGIQASMSRKGNSQDNGRMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYN
                     NKRIKVKLKGLSPVQYRTKSFE"
     gene            complement(679..1701)
                     /gene="cbpF"
                     /locus_tag="VVR39_001924"
                     /pseudo
     CDS             complement(679..1701)
                     /gene="cbpF"
                     /locus_tag="VVR39_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(1720..2545)
                     /gene="cbpG"
                     /locus_tag="VVR39_001925"
                     /pseudo
     CDS             complement(1720..2545)
                     /gene="cbpG"
                     /locus_tag="VVR39_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(2626..2865)
                     /locus_tag="VVR39_001926"
     CDS             complement(2626..2865)
                     /locus_tag="VVR39_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031335.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3015..3281)
                     /locus_tag="VVR39_001927"
                     /pseudo
     CDS             complement(3015..3281)
                     /locus_tag="VVR39_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3306..3617)
                     /locus_tag="VVR39_001928"
     CDS             complement(3306..3617)
                     /locus_tag="VVR39_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU6031336.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3542..3773)
                     /locus_tag="VVR39_001929"
                     /pseudo
     CDS             complement(3542..3773)
                     /locus_tag="VVR39_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3774..4406)
                     /locus_tag="VVR39_001930"
     CDS             complement(3774..4406)
                     /locus_tag="VVR39_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6031337.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4420..5415)
                     /locus_tag="VVR39_001931"
     CDS             complement(4420..5415)
                     /locus_tag="VVR39_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6031338.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSLTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5412..6110)
                     /locus_tag="VVR39_001932"
     CDS             complement(5412..6110)
                     /locus_tag="VVR39_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU6031339.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EIVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6188..7198)
                     /locus_tag="VVR39_001933"
     CDS             complement(6188..7198)
                     /locus_tag="VVR39_001933"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU6031340.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7182..8189)
                     /locus_tag="VVR39_001934"
     CDS             complement(7182..8189)
                     /locus_tag="VVR39_001934"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU6031341.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDVYTPLLRQ
                     LKEASQDLQTVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8176..9129)
                     /gene="mvaD"
                     /locus_tag="VVR39_001935"
     CDS             complement(8176..9129)
                     /gene="mvaD"
                     /locus_tag="VVR39_001935"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU6031342.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9111..9989)
                     /gene="mvk"
                     /locus_tag="VVR39_001936"
     CDS             complement(9111..9989)
                     /gene="mvk"
                     /locus_tag="VVR39_001936"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU6031343.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10111..10440)
                     /locus_tag="VVR39_001937"
     CDS             complement(10111..10440)
                     /locus_tag="VVR39_001937"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031344.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
BASE COUNT         3109 a         2453 c         1881 g         3134 t
ORIGIN      
        1 taaaatgtga cggcaagaag gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa
       61 caatggaaaa gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc
      121 tttacttatc accagtttta gatggcttta atagcgaaat tatcgcctat aatctttcaa
      181 cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaca gaaaagcact
      241 atgagaatac gattctccat agtgaccaag gctggcaata ccgacacgat tcttatcatc
      301 ggttcctaga gagtaaggga attcaagcat ctatgtcacg caagggaaac agccaagaca
      361 acggtaggat ggaatctttc tttgggattc tgaaatcgga aatgttttac ggttatgaga
      421 agtcgtttca gtcgcttaag caattggaac aagctattgt agactatatt gattactaca
      481 acaacaagag aattaaggta aaactaaaag gacttagtcc tgtgcagtac agaactaaat
      541 cctttgaata aattatttgt ctaacttttt gggggcagta cattgttaac ttgatactat
      601 gcgttttttg attgtgaaga cttttatcca cctattatac aaagtcaagt atccatcaca
      661 gtttacaatt agccttcatt acttaaccca ttcaccatta tagtttaagt agtaaccacc
      721 tactgtggta ttaacagcta aagcacctga atcataggca tagtaccagt taccattgac
      781 ttggaaccag cctgttttca tatctccatt acttgcattt agatagtacc aagtcgaacc
      841 ttcctgatac caaccagttg ccatagctcc tgatgaacgg agatagtacc atttgttccc
      901 aaggttttgc caaccagttt tcatatcgcc attttcagca tctaaatagt accaagttga
      961 accatcttga taccagccag ttgccatagc tcctgatgaa cggagatagt accatttatt
     1021 accaagatgt tgccaacctg tttgcatgat gccagttgct ggatctaggt agtaccatgg
     1081 agcaggtttg agcttctctt catcataggt aagagggtaa tccttaaccc aaccacgtgc
     1141 tagctctcca accgtcaatc tgttgatgcg agaatcaaag ccaccatcct tctgcaaata
     1201 ataccagtcc ccatcatcat aaacccaacc agtttttaaa gtatgataac tacgctgatc
     1261 ttcaaaataa tagattcgtt tctctgctgg gctatcatat tcttccccat gatgtttgtt
     1321 ggtatttgta gcagtttttg cttctaaaac ttgcttgcca acaaattatt gtaatacacc
     1381 atcttgacca aaataaaacc aatctggtct aagagcaatc tctattcttg gagaaggacc
     1441 aatcgtaacc cccttgtgtg gagcaggtat atattgccag ccgacaacca tctctccgga
     1501 taaaggatca aaataatagt atttcccatc tatcactctc cagtaggttt cttttagatc
     1561 cccctttttg tagtaggttc taccattttc ttggacaaac tgccatcctt cagaatcatc
     1621 tgcaaatact gtactggtcc ctagcaaacc gaagaaaaat gtggctagta cgacttgcat
     1681 cattttttta aaaagcttca ttttatatat cctccaacat caaatccact caccagatga
     1741 agcgaagtta taaactttac catcgatagt ttggctacct gtaaccattg ctctatttga
     1801 attgagataa taccattttc catttacttt ttgccaatct gtaagcatct taccggaact
     1861 gtctaaataa taccaagtat catttatctc ctgccaaccc gtttgtttat catgttgtct
     1921 ataatagtac caactaccat ttattttctt ccatccttca agagagtaac ctttaagaac
     1981 cgaataaata aataaatggc aaatttcgtt catttaattt aactgcactg ttaatttgat
     2041 tagctccatc tcctaaagta tgcactccta ctacgcggtg actagcatca taaactgcag
     2101 atccactaga cccctctaaa gtatcaactt ggtaatccaa gaacatgcca tcatcactta
     2161 aaacttgttt tttatctgta tacatttgat gaattttaaa attatatgat agatagcctg
     2221 tgatagtcac agttattcct gtcaaatttt tttgactagt aggaagaccc aaagtcccta
     2281 attttgcacc aatgggctct tctagaatta ataaagccaa gtcatattcc cttgcattct
     2341 tagaatttaa atttctaaat tccttcaaat aacgaacttc ctttactttg atctttccaa
     2401 atagttcttg acttggacta acagccggaa gaacataaat atcatccgct tctttcccat
     2461 agtcatgtct gtagtagttg tgagccgctg taattaacac attatcttta ataaaattcg
     2521 cacttcccct cccttctaca ttcattccat cggctactcc ataatactta gataaaacca
     2581 tagctgaagt cgaatacgga tactgtaaag tattatcaat tttaatcaaa tcatcattac
     2641 cgataatact tctgattgct tttggtagta tgaaccatac gttggtgaaa tctcagataa
     2701 tgaagaatca ttagactctg gacctttttc tagtgtctca cttacctcat attcttcacc
     2761 tgtactagaa ataacactca aagcagatac tgtcgataac tggctagcca ataaagtact
     2821 cgcaataatt gaaataccca attttttata aacagttttc ttcattatcg tatcctccta
     2881 atgtaattat agcgtactat tctaaatttc tcaatctact atagaatcaa gaaatctacc
     2941 accttcttta aataccctcc attatcacat aaacaggtaa acttttcaat taatgactgc
     3001 gcttttcaat cacgctagag gtacttgctt gcttctttga tactaagttc agccattctt
     3061 tccttgtttt tctcaataaa gcatgttacc caagtgggat tcgttttgga gtagtctcgc
     3121 agagtccagc caatggcttt attgataaaa aattctgttt ggttcaagtt atgaaggaga
     3181 atcttttcca ttaattgagt attggtcttc tcttttctta acaactggtg gtcaatagcg
     3241 acacgtctca gccagatatt atctgatagg ctccatttta tactcaatga aaatcaaaga
     3301 gcaaactagg aagctagccg cagattgctc aaaacactgt tttgaggttg cagatagagc
     3361 tgacgtggtt tgaagagatt ttcgaagaat attaagatta tttcttctag ttcagggtgt
     3421 ttatacacca aactccctac tactcgatct aggatatcta ccgtgtccca ccaggatttt
     3481 gtcacgacta actgctctag cttaggcaaa tcggtttcct ttagataaga ctgcattgct
     3541 ttcaaatagt tagcagccac atattggtat tttctaggct ccttttccca gcaagtgtct
     3601 gcaaaatccc aatcgataat ctttgttttt ttcgcttctg gaaaatattt ttatagagtt
     3661 tatttctttc aacctagaaa agaaaattga tggcgcatat aggcttccat gggccttgct
     3721 tttttagagt cttttgctgc ttctagctcc tcaagtaaat ctgctaaacc catctaaaac
     3781 tcctcttgcc ccaccaaatg gtgctgaaag gcgtagacag ccgcctgggt acgatcactg
     3841 acttcaagtt tggcaagaat gttggacacg tgggtcttga ccgtcttgag agagataaag
     3901 aggtcatctg cgatgcgctg attttcgtag cccttggcga tgagttggag aacatctcgc
     3961 tcacgcgcag tcaattcttc atgaagttcc atatgattgc ggtggtattc aaccttcttg
     4021 ctaacctctt gctcaatggc cagctcgcca gcagctacct tactgacggc atgaagcaat
     4081 tcatctgcac tagaagtctt gagcatatag cctttggcac cagcatctaa gactggcatg
     4141 attttttcat tgtccagata agaggtcaca atcaaaatct tggcttcagg ccattcttta
     4201 aggattgcta aggtcgcgtc aatcccattc atctcaggca tgacaatatc catgacaatg
     4261 acatctggac gcagttccaa ggccaagtca atcccttgag acccgttgga cgcctcaccc
     4321 acaacttcta catcgtcttg gaggtcaaag tagcttttca agcccaatcg gaccatttca
     4381 tggtcatcta ctagtaaaat tttcatcttt actcctttat cattccttat ctaacagggg
     4441 aatacggata tcaaccgcca gcccttgctt gggagctgtc aagagttgaa ctgttccagc
     4501 catatcttca acccgctcct tgatatttcg cagtccataa ctcaagtcgt ctaagctccc
     4561 taactggaaa ccaatcccat tgtccaccac cttcagttgc aattcaacat ctgtctgata
     4621 gaggtagaca tctaggcaag atgcctgggc atggcggagc gtattgctaa tcaactcttg
     4681 caggatacgg aagatatgct cctcgatttt cttaggcaat ttcgtcatat tctgcttgag
     4741 actaacccta agatcactct tgtcctcaag ctcttttaag agaatttgaa tcccttctat
     4801 caagctcttc tgctccagtt caactggtcg caaatgcaag agcaaaaccc gcaaatcctt
     4861 ctgggcagtt tctaaaatag ctgtgacact ctgcaactgg atctgcatct tttctctatc
     4921 taatttcaaa gcctgctgac tgatacccga taaaatcatg tgggccgcaa acaactcctg
     4981 actgactgta tcgtgcaaat cccgagcaat tcgcttccgt tctttctcga tgatttcctc
     5041 ttcctgagca aggctatgat tttcagcttt ttgaagagct tctgtcaaaa ggttaagttt
     5101 acctgataag gacttgaaac tggcatccaa atctggatct acaacctgaa ctacttcttg
     5161 ccctgccaat aaacgcttga gattggcctg catttttctt agagaaagct cttcgatccc
     5221 tcgccaaaac agggctaaga gacaggtcag ggacatgctg aaaaccaaca ataaaaagac
     5281 aaatttttct gttttttcga catcgtgcaa aaagatagac cagtcaaaat caagtatttc
     5341 cagcaagcta tgggagaaaa aaaagacaaa caggaaggag gtgagagcga taatgacata
     5401 ggcttgtttt ttcatcctct aaccacctcc acatcaccaa tcatagtggt caagaaaatc
     5461 ttgacactct tgttactctt gagatagtct tttgtttctt gatgatagtg ttcattgcgg
     5521 agggctcgct tgggctggtt gaaaaaagtc aaatccccat agagacagtt aacgctgaga
     5581 ctgacttcca catctacagg tacgatgatt ttggtcgttc ctaccatctt tctgaggata
     5641 atgacattgt catgattggt taagatgacc ctctccagat gaatagtgtc cttgcccatg
     5701 aagcgaaaga gattgatatc atcgaattgg caagtctggt agcttgaaaa atgatgaaga
     5761 tttccaaacc aacgattttt ctccttctta accgtcacga tctcttcaaa aaccaaattg
     5821 gtctgctctt tttcctggtt catcatcggg taaagaagaa agaggctata gataaccgca
     5881 acaaaaatag ctagaatcac aaaaggattg agcataacga tgaaaaagaa gagaatggtt
     5941 accgctacta aaagaagatt atttccctct ttaccagtgt agtagcgaat caaaagcaaa
     6001 aagaggaata gtatcagcag aaaacgcgaa aaatgctctg ataccatcaa aatcagagct
     6061 cctgtcagaa gacaggcttc gataaataaa aagattttaa attttctcat aggttcatcc
     6121 tctcccttct attttatcac aattcaaaaa agtcacctca gtctgaggat ggaaaaaaag
     6181 gcgctggtta cgcctttttc atctgatcat ttgcttcttt taattttcca taaagaagat
     6241 agtctacttt ttgtagatct gctatggtgg cacagttaag ggaacacata atcaagcgta
     6301 gatctgcttt ccagccttga acaatgccaa tcacttcttc aactgtgtag gtttcaacca
     6361 attccagaac ggttcgtgac aatcccacag ccttagcacc aaaaaccaag cacttaatca
     6421 tatccagcgg attccgaacc cctccactaa ccaagagttc gaccttatct ttccattctt
     6481 gggcattgag aagggcctgc atggtagact gaccccattg attgaggtaa tcacgctggc
     6541 cactacgacg gttttcgata taggcaaagc tggtgccacc acgacccgat aggtccactg
     6601 tacgaacacc gaattcatag gctctttcga ttgtcttggc atccattcca aagcccactt
     6661 ccttgaggac aataggaacg ggaatttgct tgctataatc tgctagatgc gattgccagc
     6721 ttctaaactt cctttctccc tcgggcatga gtaattcctg catgacattg acatgcactt
     6781 gcaatagaac aggattcatc tcttctacag tctgaagccc taactcgaca ggcttgtcca
     6841 atccaatatt ggttccaagg aggagattgg gatgactaga cttgacagaa aaagaatcat
     6901 ccgttggatt tttgagggct gcgctataag aacccgttac aaataaaata ccacaggatt
     6961 ccgccacctg agccagcttt tgattgattt ctcttccctt attacttcca ccagtcatgg
     7021 cattgatata aaaaggaaag tcccactttc gaccagcaaa ctctgtcgaa agatcgattt
     7081 catccagatt gtaaagaggc aaggaagaat gaatcagctc cacctcatca aagctattat
     7141 aggaactttt ctgctcaagg gcatagagga tatgctcgtc cttacgattt gtcgtcatgt
     7201 cctatccttt cttgatataa gagctcaatc cccagatcgg cccaacgatt ttttaaggtt
     7261 tcggttgatt gcgcatcaaa actcagggcg atgccacagt caccaccacc agcaccacta
     7321 ctcttggcaa cggtctgcaa atcttgactg gcttctttca actgtctaag caaaggcgtg
     7381 taaacatctg tactcaagcc ttctaaaagc ttgctggcta cttctacttg ctcgataact
     7441 ttttcggctt tcccctgctc caaggcttcg accaaagaaa ccaccgtttc ttttgaggaa
     7501 gttaaaaaat tttgattgat attttgcttg atttgctgga ccatgtgact cgatacagcc
     7561 acttccttgg tccatcccac taagaaatca cattctaaag ttggtttcac ttgtgagata
     7621 aaaaatcccc aatcacgctc cagaactgtc gccaagtttt cttcttctaa ccaagcagcc
     7681 accttctggc gatcaaatga ctggtagaga accaaatcct ctgccacaat acaggcaagg
     7741 tcgcccatgg aaccattgtc tcctcgcttg agcaagacag cgctagtcag cttgaacaag
     7801 agattctgat caaccgaaag attatagaga gccagtaaag ccttgacaac caagacaacg
     7861 acgctgccac tagaacctag accaaacttt ttcccttctc gttccatttt gccacagatt
     7921 tctagagaaa aaggtcttaa attctgacca cgaacagcga ggaagtctcc catcaaagca
     7981 atcgtttctt gaatcaagct atagtcagga ttgggcctta agtccactgc gaaatcaaac
     8041 atatctgaat agatacggta gctatcagaa aaagcaatct cagccctcat atagatggga
     8101 atatccttta tcaaagctaa ctgccctggc tctaaaatag catattcacc tgccaaatag
     8161 agttttccgc aagttttaac agcaatcatc ttgactcaaa tcctttgttt ttgacacaat
     8221 caagcgataa cgctgaccga aaatttctga taaatgctcc aagtctttct cctgacagaa
     8281 gaccttaaca ttgggaccag catccatggt aaagtagcag gcctctcctt tctcacgaag
     8341 ctggcgaaca aagtccatag cctcataaga ggcatccgtc agataagaaa aggctggact
     8401 agcagtcttt gtcgtagcat gcatagccag ggcatttttc tccgttaatt ctccaatctt
     8461 ggcaaaatca ttttccttga gataaatcag catatcctga tagtccttct cagactgacg
     8521 aacccagtcg tcaaaagtcg tcgaggtttc cacacaaagt ttcatcccgt cacggctaga
     8581 gattggtttt ttcttgtcct ctagcaccaa cataatcata gctagtttca agtctgtctc
     8641 tacagggtaa atttctccac tatccttatc ccaggctcct agtggtccat aaaaactccg
     8701 agaagaagag cctgaggcaa atttggcttc ctgtgccaac tgacttctat ccaatccaag
     8761 cttgaaataa gcattacaag ccttgaccag ggcggacaaa ccactagaac ttgaggacag
     8821 gcccgctgca gtaggcatat tgttttgagt atcgatacgg acaaagccct caccagctgg
     8881 acgataacgg tcaataatct tactcatctt agcatgctcg acctcatttt gtagctgacc
     8941 attgatgtaa aattcgtcag ctgttacatt ggctggtaaa ggcgacaagg tcgtctctgt
     9001 atacatattt tccaaagtta gagaaatact gctagtagca ggcaccatct ctttttcttt
     9061 tttctttccc caatatttga taatagcaat atttgcgtag gaacgtactg ttacaggctc
     9121 tctatccatg tctgaacagc tcctttctct tctaatcttt ctgctagttc ttgtgcgtgt
     9181 gtcaaattgg ttaccaaggc tatgatacaa cctcctagcc caccaccgct catcttggca
     9241 cccagagcac catggctaag agtcgtttca accaaaaagt ctgcctcagg gctactgact
     9301 ccaatttctt ttaaatgtaa atgcgcttga ctgaggattt gtcccagtcc ttcagcatct
     9361 ttttgtgaaa tcgcaacttc tgcttgctgg gttaattctc ccaaggcatg caaaaacggt
     9421 agggcatcct tgcccttatt ttgaaccact tggatggctt cacgagtatg accataaaca
     9481 cccgtatcgg caatcaccaa ataggcggat aaatccatct caagttctgt aaatcctacg
     9541 ttcttgataa agcgaatagg ttggtcactg agacaggtct tagcatccaa accactagga
     9601 ttcatatggg caatcatttc agctcgattg accaagattt ctagtacatc atgaggcaga
     9661 tcagcctgat agtagtcaaa taccgcacga atggccgcta tgctgatagc cgctgacgaa
     9721 cccatccccc gtttctcagg gatagccgag tcaatctcac aacgaatgca ggcttctgtg
     9781 atatccaaat actccagtga ggcataaacc gccatggaca aggtatcctc ctcataaagg
     9841 cgccaaggac tctctgcagg aactacctta caggtcacct ccacctccaa aagaggcagg
     9901 gaaatggcag gataaccgta aacgaccgca tgttccccta ttaaaattat cttactatgt
     9961 gcctgaccga caccaacttt ttttgtcatt ttttcctttt actagacgaa aaaacgtctt
    10021 atttttcata caagtattaa ttctttccta tctattttat tatattttca caaaaaaagc
    10081 gattgtttcc attcacaatc gcttctttca ttattgaacc cattcgccat tataattgac
    10141 aaaatagcca tctacggtcg tattcactgc caaggcacct gagctataag cgtagtacca
    10201 tctgccattg acctggaacc aacctgtcgt catagaacga cgaaagaaac tccataccgt
    10261 taagtaaaga ggaaagtcgt gagggatcat gcgccattga caacctgttt tagtgacgta
    10321 caaagtctca ttaacaagta ctcgtttcgg ccatttatag gtgcggtgtt tggagaaata
    10381 gggttcaatc ttagcccatt cttgatcgtt taaatcagta tcatatgctt tgcgtgtcat
    10441 aactctagtt taacattttt tgtgaataca agttctaaat aatcgaccac gaaaatttct
    10501 taagtggaaa acgccttatg aagtatgcta cgggaaactt atgcacttaa tttgacaatt
    10561 caagatgtaa aaatata
//
LOCUS       DAVHSL010000069        10468 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000069 DAVHSL010000000
VERSION     DAVHSL010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.071"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            314..2242
                     /gene="glgB"
                     /locus_tag="VVR39_001938"
     CDS             314..2242
                     /gene="glgB"
                     /locus_tag="VVR39_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU6031345.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNPKGVENEK"
     gene            2232..3374
                     /locus_tag="VVR39_001939"
     CDS             2232..3374
                     /locus_tag="VVR39_001939"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU6031346.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3364..4503
                     /gene="glgD"
                     /locus_tag="VVR39_001940"
     CDS             3364..4503
                     /gene="glgD"
                     /locus_tag="VVR39_001940"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU6031347.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFDGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4500..5933
                     /gene="glgA"
                     /locus_tag="VVR39_001941"
     CDS             4500..5933
                     /gene="glgA"
                     /locus_tag="VVR39_001941"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU6031348.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5992..6637
                     /gene="serB"
                     /locus_tag="VVR39_001942"
                     /pseudo
     CDS             5992..6637
                     /gene="serB"
                     /locus_tag="VVR39_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            6646..7761
                     /locus_tag="VVR39_001943"
     CDS             6646..7761
                     /locus_tag="VVR39_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU6031349.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7758..8204)
                     /locus_tag="VVR39_001944"
     CDS             complement(7758..8204)
                     /locus_tag="VVR39_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU6031350.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8368..9672
                     /gene="eno"
                     /locus_tag="VVR39_001945"
     CDS             8368..9672
                     /gene="eno"
                     /locus_tag="VVR39_001945"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU6031351.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9810..10238)
                     /locus_tag="VVR39_001946"
     CDS             complement(9810..10238)
                     /locus_tag="VVR39_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6031352.1"
                     /translation="MRKHGFISKRYYQVAIPFTRLFCLVSIDYINCLSETTDKNWHKS
                     DRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKT
                     ITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(10156..10347)
                     /locus_tag="VVR39_001947"
                     /pseudo
     CDS             complement(10156..10347)
                     /locus_tag="VVR39_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3140 a         1846 c         2287 g         3195 t
ORIGIN      
        1 tcctgttatt atttcatttt actatatata atacattgga gttaaaatag tacactttga
       61 tttctaagac attgttagaa attagattaa agtccttaat cgatttgcgc atgttttatt
      121 tcatttcact atagtagaaa aagaaaggcg ttttcgcaat tttttgaaaa aatattgatt
      181 tacaattgaa cgagtaagtg aacttgttgt agattttcaa aataattaaa gaagtatagt
      241 aatttacttg aatcttctct aaaaaggtag tataacaaaa acatagaaaa cgcttacagg
      301 agaaggggag tatatggata atagagaagc attaaaaacc tttatgacgg gtgaaaattt
      361 ttatctccaa cattatctag gagcacatag ggaagaacta aatggagagc atggctatac
      421 cttccgtgtt tgggcaccta atgctcaggc tgttcacttg gttggtgatt ttaccaactg
      481 gattgaaaat cagattccaa tggtaagaaa tgattttggg gtctgggaag tctttaccaa
      541 tatggctcaa gaagggcata tttacaaata tcatgtcaca cgtcaaaatg gtcatcaact
      601 gatgaagatt gacccttttg ctgtcaggta tgaggctcgt ccaggaacag gggcaatctt
      661 aacagagctt cctgagaaga aatggaagga tggactttgg ctggcacgaa gaaaacgttg
      721 gggctttgaa gagcgtcctg tcaatattta tgaagttcac gctggatcat ggaaaagaaa
      781 ttctgatggc agtccttata gttttgccca gctcaaggat gaactcattc cttatctcgt
      841 tgaaatgaac tatactcata ttgagtttat gcccttgatg tcccatcctt tgggcttgag
      901 ttgggggtat cagcttatgg gttacttcgc tttagagcat gcttatggcc gaccagagga
      961 gtttcaagat tttgtcgagg agtgtcatac ccataatatt ggggttattg tggactgggt
     1021 accaggtcac tttaccatca acgatgatgc cttagcctat tatgatggga caccgacttt
     1081 tgaataccaa gaccataata aggctcataa ccatggttgg ggtgccctta attttgacct
     1141 tggaaaaaat gaagtccagt ccttcttaat ttcttgcatt aagcattgga ttgatgtcta
     1201 tcatttggat ggtattcgtg tggatgctgt tagcaacatg ctctatttgg actatgatga
     1261 tgctccatgg acacctaata aagatggcgg aaatctcaac tatgaaggtt attatttcct
     1321 tcagcgcttg aatgaggtta ttaagttaga atatccagat gtgatgatga ttgcagaaga
     1381 aagttcgtct gcgaccaaga ttacgggaat gaaagagatt ggtggtctag gatttgacta
     1441 caaatggaac atgggctgga tgaatgatat cctccgtttc tacgaagaag atccgatcta
     1501 tcgtaaatat gactttaacc tggtgacttt cagctttatg tatgttttca aggagaatta
     1561 tctcttgcca ttctcgcacg atgaagtggt tcatggcaag aagagtatga tgcataagat
     1621 gtggggagat cgttacaatc aatttgcagg cttgcgcaat ctctatacgt accaaatttg
     1681 tcaccctggt aagaaattgc tcttcatggg tagcgaatac ggtcaattcc tagaatggaa
     1741 atctgaagaa cagttggaat ggtctaacct agaagaccca atgaatgcta agatgaagta
     1801 tttcgcttct cagctaaacc agttttacaa agatcatcgc tgtctgtggg aaattgatac
     1861 cagctatgat ggtattgaaa tcattgatgc ggataatcga gaccagagtg ttctttcctt
     1921 tattcgtaag ggtaaaaagg gagaaatgtt agtctgtatc tttaatatgg tacctgttga
     1981 gcggaaagat tttacaatcg gactacccgt tgcaggaatt tacgaagaag tatggaatac
     2041 tgagttggaa gagtggggag gcgtttggaa agaacataat caaactgttc aaacgcaaga
     2101 aggactatgg aaagattatg agcagacctt aacctttacc ctaccggcta tgggagcaag
     2161 tgtatggaaa atcaaacgtc gcttgaaatc tactaaaacc gtcacaaata aaaacccaaa
     2221 aggagtagaa aatgaaaaat gaaatgttag ctttgattct tgctggtggg caaggaactc
     2281 gtctcggtaa actcactcaa agcatcgcaa aaccagctgt gcaatttggt gggcgctacc
     2341 gtatcattga ctttgcacta tcaaactgtg ccaactcagg gattcataat gttggggtcg
     2401 ttacacagta tcaaccactt gctctcaaca accatattgg gaatggttca agctggggac
     2461 tagacggtat taattcaggt gtctctattc ttcaacctta ttctgcaagt gaaggaaatc
     2521 gttggtttga ggggactagt cacgctattt accaaaatat cgactatatc gacagtgtca
     2581 atcctgagta tgtcttgatt ttgtctgggg atcacatcta caaaatggac tatgatgata
     2641 tgctccagtc tcataaggat aataatgcca gcttgacagt agcagtttta gacgtccctc
     2701 ttaaagaagc aagccgtttt ggtatcatga acacagatgc taacaatcgt attgttgaat
     2761 ttgaagaaaa accagctcaa cctaaatcta caaaagcttc tatgggaatc tacatttttg
     2821 attggcaacg ccttcgtaat atgttagtcg ctgctgaaaa gagcaaggtt ggcatgtcag
     2881 actttggtaa aaatgtcatt ccaaattacc ttgagtcagg tgaaagtgtt tatgcttacg
     2941 aatttagtgg ttattggaaa gatgttggta ctattgagtc actttgggaa gcgaacatgg
     3001 agtatatttc tccagaaaat gccttggata gtcgtaaccg tcaatggaag atttactcaa
     3061 gaaacttgat ttcaccacca aacttcctcg gggcaaatgc tcatgtggaa gactcattag
     3121 ttgtagacgg atgtttcgtt gatggaactg ttaaacattc tatcctttca acaggcgcgc
     3181 aagttcgcga aggagcggaa gtccttgatt cagttatcat gagtggagct atcattggtc
     3241 aaggagctaa gattaaacgt gccattattg gtgaaggtgc gattatttct gacggtgtcg
     3301 aaattgatgg aacagatgaa gtacaagttg taggatataa tgaagtagtg ggggtagcaa
     3361 cagatgaaga ttgataaata ttctgccatt ttaggaaata cagttggttt tcacgatatg
     3421 tcgacattga cggaccaccg tccagtagca agtttgccat ttgatgggaa atatcgtttg
     3481 attgacttcc cactttcaag ccttgctaat gcaggtgttc gtagtgtctt tggtattttc
     3541 cagcaggata atatcagctc agtctttgac catattcgtt cagggcgcga gtggggctta
     3601 tcaacccttc ttagccatta ctatctagga atttacaata cccgtgtaga aagtagtaca
     3661 gttggaaaag aatactacca acagcttctt acttatttga aacgttctgg ctcaaaccaa
     3721 acggttgccc tcaactgcga tgttcttatt aacattgatt tgaaccaagt tttccaccta
     3781 catagtacaa caaaagagcc tatcactgta gtttataaaa aactagctaa gaaagatatt
     3841 tcagaagtaa atgcaatctt ggatgtagat gaaacagacc atgttctttc tcataaactc
     3901 tttgatagca agtcaacagc tgaaacgttc aatatgtcta cagatatctt tgtcgttgat
     3961 acaccttggt tgattgaaca cttggaagaa gaagctaaaa aagaacatcc agagaaattg
     4021 cgctatgttt tacgggattt ggctgtaaaa gagggagctt tcgcctacga gtacacgggc
     4081 tatctagcca atattcactc tgttaaatct tattatcaag cgaatatcga tatgcttgaa
     4141 tcacaaaaat tctattctct tttctcacca aaccaaaaga tttatacaaa ggtcaaaaac
     4201 gaagagccaa cttactatgc taatacatct aaggtaagca cttctcagtt tgcctctggt
     4261 agtattattg aaggtcaagt agctaattct gttctatcac gtaatattca tgtccataag
     4321 gatagcttgg ttaaagatag cctgctcttc cctcgtgttg ttattggaga aggggctcag
     4381 gtcgaatatg ctatcttgga caaaggggtt gaagttgagc ctggtgttgt gattcgagga
     4441 actgcagaac atccagttgt ggttaagaaa ggtgctaaag taacagagga tattcattca
     4501 tgaaaatttt atttgtagca gcagagggtg cacccttttc aaaaacaggt ggtttgggag
     4561 acgtcattgg cgctcttcca aaatcactgg taaaagctgg gcacgaagtt gcagtgattt
     4621 taccctacta tgatatggta gaggctaaat ttggaagtca gattgaagat gtgcttcatt
     4681 ttgaggtgag cgttggttgg cgcagacagt attgtggaat taagaaaaca gtattaaatg
     4741 gtgtaacctt ctactttatt gacaatcaat attatttctt ccgtggtcat gtttacggtg
     4801 attttgatga cggagaacgc tttgcctttt tccaactggc tgccattgag gctatggaaa
     4861 ggattgactt tattcctgat cttctccatg ttcatgacta ccatacagct atgattcctt
     4921 tcttgttgaa ggaaaaatac cgttggattc aagcctatga ggacattgaa acagttttaa
     4981 ccattcataa tttagaattc caaggacaat tttcagaagg aatgttgggt gatttgtttg
     5041 gagttggctt tgaacgttac gctgatggca cccttcgatg gaacaactgt ctgaactgga
     5101 tgaaggcagg tattctctat gcgaaccgtg tttcaaccgt ttcacctagc tatgctcatg
     5161 aaattatgac tagtcagttt ggatgtaatt tggatcagat tcttaaaatg gaatctggta
     5221 aagtatctgg tatcgtgaat gggattgatg ctgatcttta taatcctcag acggatgctc
     5281 ttttagacta tcatttcaat caggaagatt tgtctgggaa agccaaaaat aaggcaaaat
     5341 tgcaagaaag agttggcttg cctgttagag cagacgttcc actggtggga attgtttctc
     5401 gtttgacacg tcaaaaaggt tttgatgtgg tggtcgaaag tcttcaccat atcttgcaag
     5461 aagatgttca gattgttctt ttgggaactg gcgatccagc ctttgaagga gctttctcat
     5521 ggtttgctca gatttaccca gacaaactat caacaaatat cacttttgat gtcaaacttg
     5581 ctcaggaaat ctacgctgct tgtgacctct tcctcatgcc aagtcgtttt gaaccgtgtg
     5641 gcttgtctca aatgatggct atgcgttatg gaaccttgcc attggtccat gaagttggag
     5701 gcttgcgaga tacagttcgc gctttcaatc caatcgaagg aagcggtact ggctttagct
     5761 ttgacaatct atctccttat tggttaaatt ggactttcca aacagcattg gacttgtata
     5821 gaaaccatcc agacatttgg agaaacctac aaaaacaagc tatggagagt gacttctcat
     5881 gggatacagc ctgcaagtca taccttgact tgtaccatag tttagttaat taatagataa
     5941 aatcgtatga tgacttcata cgatttttag gctgtttaga gaggagaact gatgtctcaa
     6001 gtaaaaggct tgtgtgtttt ggatgtagat ggaaccttaa tcctagaaga agtgattgat
     6061 cttttaggga gagaggcagg tcatgaggcg gaaatttcgc agattacaag tcgagcaatg
     6121 cgaggagagt tggtctttga aagcagttta agaaaaagag tgtccttgtt ggaaggtctt
     6181 cctattttgg tctttgataa cgtcttcaac tcaattcatc tatcgctaaa tgtcccagag
     6241 ttcatctcta ttctccaaaa aaatggcatc ctagttggtc tggtgcctgg tggatttaca
     6301 ccaatagttg gagagattag caaaatccct tggtattgcc tatttcactg ccaaccagct
     6361 tgaagtcaaa gaaggtcttt taacaggaaa attagttgga caaattataa gtccccaggt
     6421 caaaaaagaa actctggaaa aatggagaaa gaaactaaaa ctttctaaag aaagaacggt
     6481 ggcaatcggt gatggggtca ataatctatt aatgttgaag tcggcggagt taggaatcgc
     6541 cttttgttcc aaagaaatgc tcaaaaaaga aataccacat catgttgaca agagggattt
     6601 tttagaagtt cttcctttga ttgactgttt agaatgaggg aaaatatgaa gattgtaatt
     6661 gcaccggatt cgtttaagga aagcttgaca gctcaacagg tagctgaagc aataaaaaga
     6721 ggcttccaac aatcgatagc agatgtagaa tgtctcctct gccctgttgg tgatggggga
     6781 gaaggtactg tagatgctat ccgacattct cttgacctaa aagaaaaatg gatccaagtg
     6841 acagaccctt ttggacaaaa agaagccatg cgctattttc aaaaagggga actggcacta
     6901 tttgaagtag ctgacttggt tggtcttgga aaaattccgc tagagaaacg aaacccactt
     6961 caaatccaaa cttgtggtat tggagagttg attctccatc tcatttctaa agggattaaa
     7021 gatatttata tcggtgttgg tggcacggcc agtaatgatg gaggactggg gattgctgct
     7081 ggtttaggtt atcaatttta tgatagggat ggaaatgtct tgcctgcttc cggtcaatcc
     7141 ttattaaact tagcttctgt ttcaacagaa aattgctata aaattcctga aggtgttcaa
     7201 attcatattt tagcagatgt cgtgagtccc ttatgtggtc atcaaggtgc gacttacact
     7261 tttggcaatc aaaaaggtct acatccgact atgtttgcag tcgtagatca ggcgatccaa
     7321 gatttttatg aaaaattctc acctgcaaca ttagaaatta aaggagcagg agcaggtgga
     7381 ggccttgctg gtggtttgtg tgcctttgct caggcaagta tcgtgtctgg aattgatacc
     7441 tgcttggact taatcaactt tgataagaaa gtttcagatg ctgacttggt tgttgttgga
     7501 gaaggaagac ttgatagtca aagctttgct gggaaagcgc ctataggtgt tgcaaaaaga
     7561 acccctgttg gagttcctgt tattgctatt tgcggtagtc ttgctgaaga tttacctccc
     7621 ctaccatttg aaaatatcca agctgtcttt tctattttgg agaaaagtga acctttagaa
     7681 gatagtttga aaaatgccag tctctatctg gagcgcacgg ctgccaatat tgggcactta
     7741 ttaaatatgt gcaagattta gctaaaccat ttcttccata aggatgtttt ggctggttct
     7801 tcctttttaa cttcccaaag ttttggaaaa gcaagtcgaa ggtctttttc ttctacttga
     7861 actggtgcat tgctatgaat aaccaggcca aaaggagaag taatatgctc ttcagatact
     7921 atggtggctt gactatcagt ttcttttgct tcttttaagt agaaaacttg cttatcaaat
     7981 tcgatagttg gtgaaatctt cacaaatagt ggctctgctt tttcctgaag gttttctaaa
     8041 ataaataaaa agcctttttc taactgaggg ctatttgctg tgtcaatatc tacatatcca
     8101 agaactcttt cctcaaaagt accaagatag cgtctttgct catccggatt tatttttaac
     8161 ccaccatgag ctttttcaag taattgtttt gataaatctg tcatgaaaac agtatatcat
     8221 aaaagttaga ataaaacaga caaaagaaag cgattacttt ataaagttaa ggaaaagttg
     8281 cacaaagata acgttttttc ttgaaaaagg aggggtttta aggtattata gaggtgtaaa
     8341 aaatttaact cataaggaga gtaaaaaatg tcaattatta ctgatgttta cgctcgcgaa
     8401 gtcctagact cacgcggtaa cccaacactt gaagtagaag tttacactga atcaggtgct
     8461 ttcggacgtg gtatggttcc atcaggagct tctactggtg aacacgaagc agttgaactt
     8521 cgcgacggtg acaaatctcg ttacggtggt cttggtacac aaaaagctgt tgacaacgta
     8581 aacaacatca ttgctgaagc tatcattggc tacgatgtac gtgatcaaca agctattgac
     8641 cgtgctatga tcgcacttga cggtactcct aacaaaggta aattgggtgc gaatgcaatc
     8701 ctcggtgtgt ctatcgctgt agctcgtgct gctgctgact accttgaaat cccactttac
     8761 agctaccttg gtggattcaa cactaaagtt cttccaactc caatgatgaa catcatcaac
     8821 ggtggttctc actctgacgc tccaatcgct ttccaagagt tcatgatctt gccagttggt
     8881 gcgccaacat ttaaagaagc ccttcgttac ggtgctgaaa tcttccacgc tcttaagaaa
     8941 atccttaaat cacgtggttt ggaaactgcc gtaggtgacg aaggtggatt cgctcctcgt
     9001 ttcgaaggaa ctgaagatgg tgttgaaact atccttgctg cgattgaagc tgctggatat
     9061 gtaccaggta aagacgtatt tatcggattt gactgtgctt catcagaatt ctacgataaa
     9121 gaacgtaaag tttacgacta cactaaattt gaaggtgaag gtgctgctgt tcgcacatct
     9181 gcagaacaaa tcgactacct tgaagaattg gttaacaaat acccaatcat cactattgaa
     9241 gatggtatgg atgaaaacga ctgggatggt tggaaagctc ttactgaacg tcttggtaag
     9301 aaagtacaac ttgttggtga cgacttcttc gtaacaaaca ctgactacct tgcacgtggt
     9361 atccaagaag gtgctgctaa ctcaatcctt atcaaagtta accaaatcgg tactcttact
     9421 gaaacttttg aagctatcga aatggctaaa gaagctggtt acactgctgt tgtatcacac
     9481 cgttcaggtg aaactgaaga ttcaacaatc gctgatatcg cagttgcaac taacgcagga
     9541 caaatcaaga ctggttcact ttcacgtaca gaccgtatcg ctaaatacaa ccaattgctt
     9601 cgtatcgaag accaacttgg tgaagtagca gaataccgtg gattgaaatc attctacaac
     9661 cttaaaaaat aaaatagttc agtgaactat tttatcccga accatgaaat tcaaaagttc
     9721 ggccgttgat ttaacaacgt ttctagcccc tcggatttta tccgaagggc tatttttgta
     9781 tttagaggac aaaaaaggga caaaactttt taaaaaatct ttttcataac tttatccagt
     9841 acattgattg cttcatcttt catattcttt gtgacgtggg tgtagatgga agtagtgact
     9901 tcagagtcgg aatgaccaac tctgtccgtg attgttttta aaggaatttt attttctgat
     9961 aagatgctaa tagtggtgtg tctgaagatg tgaggggaca gatgtttggg aattggtttt
    10021 ttaaggcgtt cgtttgctcg ctggagagac ttgctcaaga tagaactatg aactggtttt
    10081 cctgtattgg taacaaaaat acggtcgctt ttgtgccaat tcttatcggt tgtttcgctt
    10141 agacaattta tatagtcaat tgaaacaaga caaaagagcc tcgtaaaagg tattgcaact
    10201 tggtaatacc tttttgatat gaacccatgt tttctcaata ggattgtact caggtgaata
    10261 gggaggaaga ggtaaaagtt tatgcccaaa ctcttcacac aagagttcta gcttcctcat
    10321 tctatggaat cttgcattat ccataatata gtagattgaa actaaaatag tacacctcta
    10381 cttctaaaac attgttagaa ttcaatttta ctgtcctgat cgatttgtcc tattcttatt
    10441 tcattttact ataataaccg atggtgtg
//
LOCUS       DAVHSL010000070        10385 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.072, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000070 DAVHSL010000000
VERSION     DAVHSL010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.072"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            393..764
                     /locus_tag="VVR39_001948"
     CDS             393..764
                     /locus_tag="VVR39_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEU6031353.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            772..984
                     /locus_tag="VVR39_001949"
     CDS             772..984
                     /locus_tag="VVR39_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031354.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            1464..1709
                     /locus_tag="VVR39_001950"
     CDS             1464..1709
                     /locus_tag="VVR39_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031355.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            1866..2924
                     /locus_tag="VVR39_001951"
     CDS             1866..2924
                     /locus_tag="VVR39_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031356.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            3239..4216
                     /locus_tag="VVR39_001952"
     CDS             3239..4216
                     /locus_tag="VVR39_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031357.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            4593..4967
                     /locus_tag="VVR39_001953"
     CDS             4593..4967
                     /locus_tag="VVR39_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU6031358.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALPAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            5175..6077
                     /locus_tag="VVR39_001954"
     CDS             5175..6077
                     /locus_tag="VVR39_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031359.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEAILGKI
                     VDSESTLLCIGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            6133..6486
                     /locus_tag="VVR39_001955"
     CDS             6133..6486
                     /locus_tag="VVR39_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6031360.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGTYLSKRACQGICVALAMSPGT
                     FIALAGAAVLTKKLINYIKVGSFGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWNGFISVTVR"
     gene            6483..7211
                     /locus_tag="VVR39_001956"
     CDS             6483..7211
                     /locus_tag="VVR39_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031361.1"
                     /translation="MNNVDKIRKIHIIVYWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            8338..8841
                     /locus_tag="VVR39_001957"
     CDS             8338..8841
                     /locus_tag="VVR39_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031362.1"
                     /translation="MKLLDCILDYQERFNRKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDFASHTISVIQTGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKLTSCC
                     IVAKDLSKNTMKLDVIFFEDKNKISAVLGLRRDKSGVFKPVTLYFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            9127..>10385
                     /locus_tag="VVR39_001958"
     CDS             9127..>10385
                     /locus_tag="VVR39_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEU6031363.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVANQSKAEK
                     DYDAAKRDAENAKKALEDAKRAQKKYKDDQKITEEKAEEEKKASQEQQKANLDYQQKL
                     RKYINEKDSKKRSMLQKEMEEAERKDKEKQAEFKKIREKVIPSAEELTETRRKAEEAE
                     AKEPELTKKVKEAEEKVTEAKQKLDAERAKEVALQAKIAELENEVHRLETKLKEIDES
                     DSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     YSALYLEAAEKDLAAKKAELEKTEADLKKAVNEPEKPAPAPETPAPEAPAEQPKPAPA
                     PQPAPAPKPEKPAEQPKPEKTDDQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPAPQP
                     EQPAPAPKTGWKQENGMWYFYNTDGSMA"
BASE COUNT         3558 a         1381 c         1916 g         3530 t
ORIGIN      
        1 tctttccatg gggctggtcg atataatgta agggagcttg agttgttagt agaggataaa
       61 atgttaagag taatagtagt tattcaatct ttagtaataa tactgcttgc tgttgcttta
      121 ttattatctc ggaaaaactt tgattcgtta aatgttgttc ttataatgat gatcgtatca
      181 caattgttgt tattagtata tttgataaaa tcagggaatc agtgattagc tgttatttga
      241 attaagtaaa ctgttaagct tcaagcagta actggtttta aatatttaaa ataagataaa
      301 ggaaggaagt ctaatttagg taactaaaca aagcctgcga tcacttgtta ggaaaccatc
      361 ctaagcatgc ttaataaaaa aggagaaaat aaatggaact tgtattacca aataattatg
      421 ttgtgattga tgaagaagag atgatgtacc ttgatggggg ggctatatat atacccaggt
      481 gggcaattac aggagccatt actggtgcag catatgcagc attagcagca gcaggaggtg
      541 gaggccttca actagttctt gcatcttatg gattacgctc cgcactggta gctgggattg
      601 ttaaaggttt aggagtatta ggaattcata ttggaaatgc ttttgcaaat actgttatta
      661 gaagtattgc atctgctgga attggtgctg gagctgattg gatttttacc aatattattg
      721 atggctggga tgggcgacgt gataatcaat tgagaatagg ataatagtat tatgatggtt
      781 gttttaattt cagttattgt tgcattcctg tatcataaaa ttacagagta tgtcaacaac
      841 aggaaaattg atattgttat ttttctatca ttgctgattt ctcattttat ttggaattac
      901 tattttttac caattgaaat attgatagca atcagtggag caaatttatt attaagtttt
      961 ttaaaaaaat tacagattaa ataatattat tccatatgac atatcaacta ggtcattaga
     1021 ttttattgaa gatataaatt aaaaacgagg ttgggaaaaa actcaatttg aaagtgagat
     1081 tgagtaaatc tttctatcta tataacgtat atcatcaata tttttgaaca cctgataata
     1141 tgcatttttc ttattttaaa gattttttgc ctttcttcat ttcttgaatg aattggagag
     1201 atgactttat ttaggtgttt gacattacta tagataggat ttagcagtac taatatgaac
     1261 tcatattata ggtgcagact taaattttgg aagcaagcta aaggatatct tatctaggta
     1321 actaagtgct ataacaagat atattggtgg agttagtatg gcaactatta ctaatgctct
     1381 taatattgcg gctactgttg ctgaagtctt ctcattagga ggagccattg catatggttt
     1441 agatatcgta gacggtaaat ttgatggata tttatgggcg taaaactata gctatgaaac
     1501 atttttttgc aggaattggt gaaattcatt ttttgttatt tttattatat ctaagcatgt
     1561 ctaccagtcc aattattgga ctagtgattg gatatactaa aataaatcta ataaattcta
     1621 ttattatagc tcttggtatg atattggcat taattttggt attatcaaga gtgtatagaa
     1681 aatattttta tagagacgat gatgactaaa gtttttatca ataatttggg ctccttgtca
     1741 actgtagtgg gttgaataaa agctaacgtc tggggaaggg tttaaagctt tactttatca
     1801 aatattgact tacagagttg ctctattgta ttgatgtatt cttagtaaat aatatggtgt
     1861 tttgaatgaa agatgatcag aaatatttat tagcgggact ttattcgctt ctagttgcaa
     1921 tattttattt tccattgatt gattccaagg ggatttttgt aagtatattg atggcggttt
     1981 tacttttata tttaatatac ttcattgcaa cagtcattca tattgtgata attaagttta
     2041 taagaaaaaa atcttttaag tatttggttc tatatccatt tacttatgat gggagctgga
     2101 gatttcaacc tataaactta ctctactttc cagaaatggt gagagatgtc attccgatta
     2161 atttagttca agaatattgc caaggacaac cttacggact gttaaaaaag atgctgaaaa
     2221 gaattcgatt gtcacgagag atagctttac tcctggctac cattatcgtc tattttttta
     2281 cgcatagaat tctacctctt tcagtattta cgttcatgtt ctcttacata ttgctatttg
     2341 tacaatctta tttgggtagc aataccgctt ggattggaaa tagaagatta ataatagatg
     2401 atgaatttga aaaaatcttg ctttcaaaaa gttatgtaaa agaaatatca tctgcacgat
     2461 actcagaata cttgacatgt gaatacaaaa accttacacc aatcatattg atagctattt
     2521 ttgaaaattt gcttgactcc tacttgcttc agaatcagag tgaggttgac ttagatattt
     2581 tttataaagt tttacctttg ctttataaag aaaaatatac tatgggattc aattactttg
     2641 taagtttaaa ttatttacta tataaggttg gatttttggg aatcatttac gataatgaag
     2701 cattaagaga tttgtcaaaa caatatttaa acaaaaatat ttcggaatta caagatggtt
     2761 ctttcgaggg cggtatacaa gatgctgttg cctctaaaca aatagtagtt ataaatgaat
     2821 ttatagcttg tttaaattcc agatgcatgc catcccaata tgatagattt ttttataaag
     2881 atagacctta tattttttcc agaaagagtc ctattaaggg gtgaaaattt gttacatttg
     2941 gattaacaag tgtcctaggg attagaaata actctagtat agctagatat ttttgagtaa
     3001 ctagaaatat cattaggcta ctcatatgat tgccagaaaa gatggctgat gaatcttatt
     3061 tatactgttg cagtaggcgt tgtctaggat aaataagcta tcttgatggg ggagattgga
     3121 ataattttag tagaaacatt aaaggattat gggcaagtag cataggatta ggtgatgcaa
     3181 tgtgctaagt tggcttggtg ttagcagtag tattatttaa caatggaaag tagactaaat
     3241 gaaaaataag cgttattttt ttgacacaat tttaataatt ttactgctta taagcacgat
     3301 attttgtgtc agcccagtat ttataaaatt ggacatctta ggaactccct ctcatgccat
     3361 cttaaccttt gtattggcga taccgttatt ctatattttg tctcaatgct tacatacttt
     3421 gctattacta gtttcctcaa tcttttgtaa attaagacca atttattttt attttatatt
     3481 tgtgatcatt ataggagcta ggaaatacta tcgaattctc tttcaccaac taatgggatt
     3541 tagtccagga atagcagtgt tttataagga gagtcaaaca actaagaatc tgtttaaatt
     3601 ttactacttc ttgtacttta caacactaat ttcatactat tttttcttta cttttgtgta
     3661 tgacaaaccg ttgcttttgc ctcttatttc attttctatt atcatagcat tagtacaaaa
     3721 actttataga attgagaatc aacaattatt tctgttaaaa tcaaaggtac taacaatact
     3781 ggaatctaag aagaattgtg agtttaatct tcaggattat catgaaattt ggaaattgca
     3841 atcaaaatct gagttgccat gcgtggcttt atcttatatc agtttaatca agccatatct
     3901 ttcagagagt gtgcgtgaac aaattgattt attagaagtt aagcgattta aaaaaataaa
     3961 taatccaata tcactttatg gtatgttgga tgttataaaa ttaaatctat atttacggca
     4021 ttataatgaa aaaaataaat atgaatcaat gttaaagaaa attttagagg taagaccaga
     4081 ctttgtttta atcgagcaga atattgatga tagtttaaat agctcgcaac cattatcttt
     4141 atctttagcc atttcagaaa tccaactttt gcttgaagtg tatataggga tcaaacatgt
     4201 ttcaattagg agataaaact agaataatat ttgccattat aggggcaagt tgcatattag
     4261 tcagtatgta tcttattcca cttattaaaa ctgagaataa attttgggaa atacttttat
     4321 ttatattagg tgtattgcta attggaattg cgttactaag tcaaaaaaaa taaattttga
     4381 aatagtatta gtgagttcgc aatcatttat tgctagtggt ttagaactgt taagtttcaa
     4441 acaataattg attttaaacc ttaggtaacc tataaaaaca aataaggtag agaaaggata
     4501 tcttatctag gtagctaagt gataaaaaca cagtcgtcta tcacttgtta ggaaactatc
     4561 ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca aataattatg
     4621 ttgttcttga gcaagaagag atgatgtatc ttgatggggg attttctatt ccgagatggc
     4681 ctgttgcaac agccattaat atagctttta atggtgtttt aggtggagga gcaatcagtc
     4741 tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca attgctggag
     4801 cagctgcaag atatgttggg gtacgagttg caaatagagt ggcaggattt gcactgcctg
     4861 ctattaatgg atttgcagct tggatgtcaa ttggcgatgc tattacaaca atctgggcca
     4921 ataatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta gatatgggta
     4981 ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata tcatccataa
     5041 cttttttagc ctatgatttt gttagcgaag aaataaaaaa gttgattatt tggattaatg
     5101 tcgttttttt gattttaatc atagcaatga tgatttatcc aaaattaaga aaatgataag
     5161 gacactgtaa aattatgata cgtaaactaa ttgttttctt actaatgctc cctctttttg
     5221 tcttgtggct agagttgcat gtcctagtga ataacttact attgaatcta gaatctcccc
     5281 ttgattttgt gattagtatg agtcttgctt tctgtagttt gattttatca aaaatagttt
     5341 tagacatact atacgcattg aaagatttat acaagaaaga aggtcttatt aagatttttc
     5401 cctttatttt tataagaagg aaaaaagtga atgtgagatt ctcgccctat ttttcattcc
     5461 atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt tttattcttg
     5521 aaattgctat tatcctagta tttattttaa aaattccttt tgcaatcatc atgcttacta
     5581 caatattttt ctggactata atggatatca atcatctagt ttttaataag acggaatttc
     5641 tttttaatca aaacaaatgg caaaaagaag attcgtttga aagtgatttg acgaaaacgt
     5701 taaaggataa aatacaaaag tcagagctaa gttattctga cttaatgtct ctacagctgt
     5761 atgatgcgat gaaccaatcc acctttttaa cggatagtga actctttgag gctattctgg
     5821 gaaaaattgt agattctgag agcactcttc tttgtatagg acttgtagag ttgctgctat
     5881 atgaaatttc tattagtaac aataacaact ggtccaacaa ggttgataaa attaggatac
     5941 acctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta aggcaaaatt
     6001 ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta ttactgagta
     6061 ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt tcaactaagg
     6121 aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga tgaagaagaa
     6181 atgatgtatc ttgatggggg aacttattta agcaagcgtg cttgtcaagg aatttgcgta
     6241 gctttagcta tgagtccagg aacttttata gcattagctg gagctgcagt tttaaccaaa
     6301 aaactaataa actatattaa ggttggaagc tttggaggct ggcttattgg tgcagcagca
     6361 ggtgtattgg ctacagcagc aggaaaaata gcttactgta ttggatatgg tgctcttaat
     6421 agaggttgtg atattagcgg gaacccttat ccttggaatg gattcatatc tgtgacagta
     6481 agatgaataa tgtagataag attcgaaaaa tacacatcat cgtgtattgg gtgtatatat
     6541 ttttatcatt cagggcgatt ataaatgata cggagtattt tttgcttatt tttttagctt
     6601 ttatctactc aatagtatca ctacctctat attctgtgaa aaataaaata gtatctatct
     6661 gtctagccat aaattcgatt ctgttaatga gtttccccat tttaatcaat aagtttttcc
     6721 cagaaagttt tttgacttat accgtattaa taagtgtttt tattacagag ttgataattt
     6781 ttcatttaat tgggaaagat tttgctacta aattgactaa cgaatataag aaaattagtc
     6841 agtttagaag caaggtgtct caatctcctt ggataaaata tttagagatt tctagtttta
     6901 tattaactat atttccatct attctttatg gtacagttga taatcgtgta ttggctctta
     6961 tctttttgat aaaaatttgt gtagatacta cgataaaatt tttattcatc agattatttg
     7021 acacaagtac tttaatgaag aggaggatat tttttctttt cgcattggat gttatagctt
     7081 acttattttt aggatatctt ttagtgattc aaaaagcagg ctatttgttt tcggttttac
     7141 ttcttttttc taatttttca gttccattta tcaaagaaaa ggaatacgaa ttatttaaaa
     7201 atagcaagta atagaaacat aggttaaatc ttagaacggc ttaaaatcag atatgataaa
     7261 gggaaatagt cttatctagg taactaagtg ctacaaacac agtcgaggat cacttgttag
     7321 gattacattt taatcatgct taataagaat ggagaattcc tatggggatt gtattactct
     7381 gaagtttcga ataccttagt tctcgtgatt ttgagctatt ctagctttag aatccttcag
     7441 aacgtaaaat tttaagcagt caaagactta gaatagcccg aaaacattta ttttataaca
     7501 attctaagct tagaattgct catatatatg tatttgagct gctcgatagt taggacagct
     7561 ttattctgag aaatctgagc tatcaatgct tcagaatagt atttcgccaa tggtttttat
     7621 tgaagaggtg attgttttat gatagtctaa aataaaactg atttaatgga gaatcgttac
     7681 atgaaacatt tttttgcagg aattggtgag ataaaacttg ttggctactt attgtatata
     7741 tgtgtaggac tagcccctct ttttcatata tatgtcatag gttcggaact gagttttgtg
     7801 aaaatagtgt tatctatttt gggaattata tttgtaagta tgttaactat tgctcgaatt
     7861 tataggattt ttttctataa agaatagttt ggacttgaac tgtatctaaa aacagagatt
     7921 ggtcgattat cagcctcttt cttgtcgttg aaaagagtga gatatattga cttttgaaaa
     7981 aaagatgtca taattgagtt gggataaacc taaaaataat atagtagatt gaatctggaa
     8041 tagtccgtta tgaccgttaa aatatttcta gaaattaatt tgactttcct aatcgatttg
     8101 ttcacatctt gtttcaatct actatacttt ctcgttaaac cgttcggcaa ttcatggtga
     8161 catggacaca tagtagtaag cacactatgt ggcttggcag agctaaaaac tgttcccttg
     8221 cgataagcct aataagcaca acatagggag ttagagaagc cgactctaat caaacacttt
     8281 gggcagtagt gagaactgcc ccgtgctttt tattttgaga aaatatggag tttgtcgttg
     8341 aaattacttg attgtatttt ggattatcaa gaaagattca atagaaaaac atgtcaagta
     8401 tcaacgaatt ataagtattt agagactttc aaagtgaatt tttgcctgac tgatttacat
     8461 catttatttg gcttacacaa aatcacacga gattttgcta gtcatacgat atctgttatt
     8521 caaactggtg tttttatttt agaagatttt agaaatatcc tattgtacaa tgatgtaatc
     8581 gaaaggatat ctttatatga gtttatcggc gatatcttct attctaagct aacaagttgt
     8641 tgcatcgtag ctaaggattt atctaaaaat actatgaaat tggacgtcat attttttgag
     8701 gataaaaata aaatatccgc agttttaggt ttacgaagag acaaaagcgg agtatttaaa
     8761 ccagttactc tatattttac aagcgctaag aaatatgcta aagttcgtaa aacagatgtg
     8821 aaagaaatga aatggctata aagattgtcc gcaggcttaa gcttgcgttt tttgttgttt
     8881 aacgaaatta aaaaataagc tctctcattg gaaatgtttt tataggaatg aaggaagatg
     8941 atgctatgtt taaaaagaga atcgaaaagg gcaaaagtag tgtctttatc tttttggagt
     9001 agaagcttat gatatagaaa tttgtaataa aaatgtaata taaaacattt gacaaatatt
     9061 tacgggggga gtatacttaa tataagtata gtctaaaaat gactatcaga aaagaggtaa
     9121 atttagatga ataagaaaaa aatgatttta acaagtctag ccagcgtcgc tatcttaggg
     9181 gctggttttg ttacgtctca gcctactttt gtaagagcag aagaagctcc tgtagctaac
     9241 cagtctaaag ctgagaaaga ctatgatgca gcgaagagag atgctgagaa tgcgaaaaaa
     9301 gctttagagg acgcaaaacg tgcgcagaaa aaatataagg atgatcagaa gataactgag
     9361 gagaaagcgg aagaagaaaa aaaagcttct caagagcaac aaaaagcaaa tctggactat
     9421 caacaaaagt tgaggaaata tattaacgaa aaagactcca aaaaaagatc tatgcttcag
     9481 aaagaaatgg aggaagctga gagaaaagat aaggaaaaac aagcagaatt taagaagatt
     9541 agagaaaagg tgattcctag cgcggaagag ttaacagaga ctagacgaaa agcagaagag
     9601 gctgaagcaa aagaaccaga gcttactaaa aaagtaaaag aagctgagga aaaagttact
     9661 gaagccaaac aaaaattgga tgctgaacgt gctaaagaag ttgctcttca agccaaaatc
     9721 gctgagttgg aaaatgaagt tcatagacta gaaacaaaac tcaaagagat tgatgaatct
     9781 gactcagaag attatgttaa agaaggtctc cgtgctcctc ttcaatctga attggatgct
     9841 aagcaagcta aactatcaaa acttgaagag ttgagtgata agattgatga gttagacgct
     9901 gaaattgcaa aacttgaaaa agatgtagaa gatttcaaaa actcagacgg tgaatattct
     9961 gcattatatc ttgaagctgc agaaaaagat ttagctgcta aaaaagctga attagaaaaa
    10021 actgaagctg acctcaagaa agcagttaat gagccagaaa aaccagctcc agctccagaa
    10081 actccagccc cagaagcacc agctgaacaa ccaaaaccag cgccggctcc tcaaccagct
    10141 cccgcaccaa aaccagagaa gccagctgaa caaccaaaac cagaaaaaac agatgatcaa
    10201 caagctgaag aagactatgc tcgtagatca gaagaagaat ataaccgctt gactcaacag
    10261 caaccgccaa aagcagaaaa accagctcct gcaccacaac cagagcaacc agctcctgca
    10321 ccaaaaacag gctggaaaca agaaaacggt atgtggtact tctacaatac tgatggttca
    10381 atggc
//
LOCUS       DAVHSL010000071        10351 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000071 DAVHSL010000000
VERSION     DAVHSL010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.073"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            741..1124
                     /locus_tag="VVR39_001959"
     CDS             741..1124
                     /locus_tag="VVR39_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6031364.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1176..1865
                     /locus_tag="VVR39_001960"
     CDS             1176..1865
                     /locus_tag="VVR39_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6031365.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            1907..2155
                     /locus_tag="VVR39_001961"
     CDS             1907..2155
                     /locus_tag="VVR39_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031366.1"
                     /translation="MYKHLFFLDSKTLDWLTPYILVLASDTIAFNVFVLTFVSAVIFN
                     FLNPMLSLMAIFLGAGYVVGFWLLKWFVLERLELKDDV"
     gene            2185..2796
                     /locus_tag="VVR39_001962"
     CDS             2185..2796
                     /locus_tag="VVR39_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6031367.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2958..3752
                     /locus_tag="VVR39_001963"
     CDS             2958..3752
                     /locus_tag="VVR39_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU6031368.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3749..4384
                     /gene="trmB"
                     /locus_tag="VVR39_001964"
     CDS             3749..4384
                     /gene="trmB"
                     /locus_tag="VVR39_001964"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU6031369.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4511..4990
                     /gene="rimP"
                     /locus_tag="VVR39_001965"
     CDS             4511..4990
                     /gene="rimP"
                     /locus_tag="VVR39_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU6031370.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            5034..6170
                     /gene="nusA"
                     /locus_tag="VVR39_001966"
     CDS             5034..6170
                     /gene="nusA"
                     /locus_tag="VVR39_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU6031371.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6192..6485
                     /locus_tag="VVR39_001967"
     CDS             6192..6485
                     /locus_tag="VVR39_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU6031372.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6478..6777
                     /locus_tag="VVR39_001968"
     CDS             6478..6777
                     /locus_tag="VVR39_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU6031373.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKVIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6794..9586
                     /gene="infB"
                     /locus_tag="VVR39_001969"
     CDS             6794..9586
                     /gene="infB"
                     /locus_tag="VVR39_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU6031374.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9837..10187
                     /gene="rbfA"
                     /locus_tag="VVR39_001970"
     CDS             9837..10187
                     /gene="rbfA"
                     /locus_tag="VVR39_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU6031375.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3152 a         1886 c         2337 g         2976 t
ORIGIN      
        1 gtttctttaa tattgtttcg cctgtcaaaa tgatatgtga tagcaggatg aaaagtctac
       61 aaacaagttg gtatcaatac aatataaaga ggaaagtatg tttttaatgc ttacttttta
      121 aattttttaa caattcaaga tgtttcgatg acaattcaag atttggatga aaaattttaa
      181 aaaacaatga tatactaaac ttgtcaaagt tgcaacgtgt gctgctacat tatgttaaaa
      241 atcgctcttg attgataagc tggatttgtt aggaaaggag taaataatta tggataagaa
      301 aaagatagtt tcgactataa tatgtatagt atttcttgta gtgtcagtag ataatttttt
      361 tagagactta accccgttac tgttcatttt aaatattatt ggcctgtctt gcttttcagt
      421 gctaacatac attaacataa aagagatact cttaaatata agtaaatgat gatttggtta
      481 gtcctagaac caatcaactt atgtttatcg gcttggcaga ttttatgttt gtcatttgtt
      541 tgtatagagg tatttcagaa acagaattct atcaacaact aatcgcttat ataggtgtat
      601 tctctgcttg tttatcacgc ttctgctcat gtggggcttg aagtattata aaaagtagct
      661 ttctatcctt ttctgacagg atatttgagt agaaggctct attaaattgt tagtgaaata
      721 aatgaatgga ggtatttaat atgaaataca gattattttt tgttattttc ttgagtagtg
      781 tgttggatat tcttttaggg acatttttac aaatctctat cgtatctatt gggtggcttg
      841 ttctttacag tggtttgttt gaagcaggag ttttccttct tgctaataaa ggggtggcgg
      901 taaaaatcaa ggaagtagat attcgaaatc gctttaaatt tatttttgga aaaaccttat
      961 ggtttcaaat tcttttgctc atctttttga taatcaaact ttatcttggt ttggatgcga
     1021 ggttgatttt attctatgga catattttca ttgtctttaa tgccttaatg tatctattat
     1081 ctagtagtca ggttagcctt aaaaagaaca aactgtcttc ttaatcttac agcagtagag
     1141 cctgacaagg tgaggtcata gtagggagga tttctatgaa aaagtatcaa cttctattca
     1201 aaataagtgc agttttctct tacttatttt tcgtatttgg tctttctcag atgacgctta
     1261 ttattcaaaa ttattggcaa ttttcttccc agattggcaa tttcgtctgg attcaaaatt
     1321 tcttgagttt gctatttagc ggagtcatga tttggattct ggttaagaca ggtcatggtt
     1381 atctctttca cattccaaga aaaaaatggc tttggtattc gattttgaca gtattagtgg
     1441 tagtgctcca gatctctttt aacgttcaga cagctaaaca tgttcagtca actgctgaag
     1501 gttgggctgt attgatcggt tatagtggga ccaactttgc tgagctaggt atctatataa
     1561 ctttgttctt tctgactcca cttatggaag agctaatcta tagaggatta ctgcaacacg
     1621 ccttttttaa gcattcgaga tttggccttg atttgcttct tccgtcaatt ttatttgctc
     1681 ttcctcattt ttcaagcctg cctagtttgt tagatatctt catctttgca acatctggca
     1741 tcatctttgc tagtttgacc cgctatacca agagcattta tccttcctat gcggtgcatg
     1801 tgatcaataa tattttcgca acattaccat ttttgctgac ttttttacat agggtcttgg
     1861 ggtaaaaaaa caaaaggctt gcttttcagc catagaggag attatcatgt ataaacactt
     1921 atttttccta gattccaaaa ccttagactg gttgacgccc tatattctag tcttggcttc
     1981 tgacaccatt gcctttaatg tttttgtgct aacctttgtg tctgcggtga tctttaattt
     2041 cctgaatccc atgctatctt taatggctat cttcttaggg gctggctatg tggttggatt
     2101 ttggttacta aaatggtttg ttttggaaag gttagagcta aaggatgacg tgtaggaagt
     2161 ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt
     2221 ggatttttag tactaataat tgtcattaca gttccttata cgattaacca tggggatttt
     2281 tttcaaaatg aatctgcatt gattcttgta agtcttcttg taacctcgct gagtgttgct
     2341 tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt
     2401 ttcattgcaa tctttcttct aagtgtactt gagacgctgg tttatattca tttcttcgct
     2461 gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccctgtct
     2521 ttgattttga ctacctcagt ttttggcccc atccaggagg aactcatttt cagaggactt
     2581 cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt
     2641 tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact tgggggcttg
     2701 ttgctgggcc ttgcttataa aaagagccaa aacttatggg tttctactct agtccacatg
     2761 ttttacaaca gttggccact cctatattat ttataaaaat tatgaaaagg taagtaggag
     2821 attgtgctta cctttttctt tctataatga taacccaaac cactccagag gcttttcttt
     2881 gagaatcggg ttagagtggt tgacgaatag gccaaaaact agtagaatag taaggaaact
     2941 ttatacggag gaaagaaatg gatttgggtg ataatgagct aacactgact cccatacctg
     3001 ggaaaagtgg caaggcttat atgggtagct atcctgatgg gaagcgcatc tttgtaaaaa
     3061 tgaacacctc tccaatccta cctggtctag ctagagaaca aattgctcca caattattat
     3121 ggagtcgtcg tttggcagat gggcgtgata tgtgtgctca agaatggttg acaggcaaga
     3181 tattgacccc ctatgatatg aatcgtaagc aaatcgtcaa tattttaacc cgtcttcatc
     3241 gctcacgtcc gttgatgaca caattgagtc gtttgggcta tgccatggaa acacctgtag
     3301 atttactaca gtcttggcaa gaaacggctc cagatgcttt gcgtaaaaat cattttatca
     3361 gtgaagtgat ggctgattta cgtcagacta ttccaggatt tagagaggac catgcgacca
     3421 ttgtccatgg agatgtacga catagtaatt ggattgagac agatagtggc ttgatttatt
     3481 tagtagattg ggattcggtt cgcttgaccg atcgcatgtt tgatgtggcc catatgctct
     3541 gccattatat ttcagaacat cagtggaagg aatggttgac ctactacggt tacaagtaca
     3601 atcaaacggt attaagtaaa ttgtattggt atggtcaatt gtcttatttg agtcagattt
     3661 ccaagtatta tatgaaccaa gatttagaaa atgtcaatcg ggagattcat ggtttgcgtc
     3721 atttccgaga caagtatgga aagagaagat gagagttaga aatcgtaaag gggcaacaga
     3781 attactagag gcaaatcccc agtatgtggt cctcaatccc ttggaagcca aggcaaaatg
     3841 gcgggacttg tttggcaatg ataatcccat tcatgtggaa gttggaagtg gaaagggtgc
     3901 ctttgtttca ggtatggcca agcaaaaccc tgacatcaac tatatcggga ttgatattca
     3961 aaagtctgtt ttgagctacg ctttggacaa ggtgcttgaa gctggagtgt ctaacatcaa
     4021 gctcttgtgg gtagatggtt ctgacttgac tgactatttt gaagacggtg agattgatcg
     4081 cttgtatctg aacttttcag atccttggcc taaaaaacgc catgaaaagc gtcgtttgac
     4141 ttacaagacc ttcttggata ccttcaagcg tatcttgcct gaaaatggag aaattcattt
     4201 caagacggat aaccgtggct tgtttgagta tagcctagtg agcttttctc aatatggcat
     4261 gaaactcaat ggtgtctggc tagatttgca tgccagtgat tttgaaggca atgtcatgac
     4321 agaatacgag caaaaattct ccaacaaggg gcaagttatc taccgagttg aggcagaatt
     4381 ttaagaaata gcctgaaatc aggctgtata agtgcttttg ctttacataa gttagcaaat
     4441 gtgctatact aagggtaaga atatgagaaa gagaggcggg gaaatatctt cgcctcttgc
     4501 ttatgaggag gtggacgcaa tcgcaacaat cgtagaatta gtcagagaag ttgtagaacc
     4561 tgtcatagaa gctcctttcg aactcgtgga tatcgagtat ggaaagattg gcagtgacat
     4621 gattctcagt atttttgtag ataaacctga aggaattacc ttgaacgaca cggcagactt
     4681 gacagaaatg atcagtcctg tcctagacac catcaagcca gatcccttcc cagaacaata
     4741 tttcctagaa attaccagtc caggcttgga acgtcctttg aaaaccaagg atgccgtcgc
     4801 tggagcggtt gggaaataca tccatgtcgg gctctaccaa gccatcgata agcaaaaggt
     4861 ctttgaagga accttgttgg ccttcgaaga ggacgagttg actatggaat atatggacaa
     4921 gacacgtaag aaaactgtcc aaattccata tagtttagta tcaaaagcac gtttagcagt
     4981 taaattatag aaaaagaaag gatagctttt gaggattcaa aagtgaagaa aacatgagta
     5041 aagaaatgct agaggccttc cgcattttgg aagaagacaa gggaatcaaa aaagaagaca
     5101 tcatcgacgc agtagtagag tcgcttcgtt ccgcttatcg cagacgctat ggtcagtcag
     5161 acagcgtagc tattgacttc aacgaaaaaa caggtgactt tacagtttat actgtccgtg
     5221 aagttgttga tgaagtattt gatagccgtt tggaaatcag cttgaaagat gctcttgcca
     5281 ttaattcagc ttatgaactt ggagacaaaa tcaagtttga agaagcacca gctgagtttg
     5341 gtcgtgtagc agcccaatct gccaaacaaa ccatcatgga aaaaatgcgc aagcaaacac
     5401 gtgccatcac ttacaatact tacaaagaac atgagcaaga aatcatgtct ggtacagtag
     5461 aacgctttga caaccgcttt atctatgtca accttggtag catcgaagcc caattgtcaa
     5521 aacaagacca aattcctgga gaagtttttg cttctcatga tcgtatcgaa gtttatgttt
     5581 acaaggttga agacaaccct cgtggtgtga acgtctttgt tagccgtagc catccagaaa
     5641 tgatcaaacg tttgatggag caagaaattc cagaagttta tgatggaact gttgaaatca
     5701 tgagcgtggc tcgtgaagca ggtgaccgta cgaaggttgc tgttcgtagc cacaatccaa
     5761 acgtagatgc tatcggtaca atcgttggac gtggtggtgc taatatcaag aagattacta
     5821 gcaaattcca cccagctcgt tacgatgcta aaaatgaccg catggtacca atcgaagaaa
     5881 atatcgatgt tatcgagtgg gtagcagatc cagctgaatt tatctacaat gccatcgctc
     5941 ctgctgaggt tgaccaagtt atctttgatg aaaacgacag caaacgtgcc ttggtggttg
     6001 ttccagataa caagctttct cttgccattg gtcgtcgtgg acaaaacgtg cgcttggcgg
     6061 ctcacttgac tggttatcgt atcgatatca agtctgctag cgaatttgaa gccatggaag
     6121 acgctgcttc agtagagttg gaagtagaaa acgatactgt agaagaataa aagctgctag
     6181 aggagggaaa gatgaaaaca agaaaaatcc ctttgcgcaa gtctgttgtg tctaacgaag
     6241 tgattgataa gcgtgatttg ctccgcattg tcaagaacaa ggaaggacaa gtctttattg
     6301 atcctacggg caaggccaat ggccgcggcg cttatatcaa actagacaat gcagaagccc
     6361 tagaggcgaa aaagaagaag gtctttaacc gcagctttag catggaagtg gaagaaagct
     6421 tttatgacga gttgatcgct tatgtggatc acaaagtgaa aagaagagag ttgggacttg
     6481 aataagcaaa agataagtaa tctcttgggg cttgctcagc gagcagggcg catcatatcg
     6541 ggtgaagaat tggtggtcaa ggtcattcaa gacggcaagg ccaagttggt ctttctagct
     6601 catgatgctg gacccaatct gaccaagaag attcaagata aaagtcatta ttatcaagta
     6661 gaaattgtaa ccgtgttttc aacactggaa ttaagcatag cagtcgggaa atcgagaaag
     6721 gttttggctg taacagatgc tggatttaca aagaaaatga ggtctcttat ggaatagaag
     6781 aggaggacat gatttgtcta agaaaagatt gtacgaaatc gcaaaagaac ttggaaaaga
     6841 aagtaaagaa gttgtagcgc gtgcaaaaga gttgggcttg gatgtgaaaa gccactcatc
     6901 aagtgtggaa gaagctgtcg ctgcaaaaat tgctgccagc tttaagcctg cagctgctcc
     6961 gaaagtagaa gcaaaacctg cagcaccaaa agtaagtgca gaaaagaaag ccgaaaaatc
     7021 tgagccagct aaaccagctg tagctaagga agaggcaaaa ccggctgagc cagttgctcc
     7081 gaaaacagaa aaagtagcag cgaaaccgca aagtcgtaat ttcaaggctg agcgtgaagc
     7141 ccgtgctaaa gagcaggcag aacgacgcaa gcaaaataag ggcaataacc gtgaccaaca
     7201 acaaaacgga aaccgtcaga aaaacgacgg ccgtaatggt ggaaaacaag gtcaaagcaa
     7261 ccgcgacaat cgtcgcttta atgaccaagc taagaagcag caaggtcagc aaaaacgtag
     7321 aaatgagcgc cgtcagcaag aggataaacg ttcaaatcaa gcggctccac gtattgactt
     7381 taaagcccgt gcagcagccc taaaagcaga gcaaaatgca gagtacgctc gttcaagtga
     7441 ggaacgcttc aagcagtatc aggctgctaa agaagccttg gctcaagcta acaaacgcaa
     7501 ggaaccagag gaaatctttg aagaagcggc taagttagct gaacaagcac agcaagttca
     7561 agcagtggtt gaagtcgtcc ctgagaaaaa agaacctgca gtggatacac gtcgtaaaaa
     7621 acaagctcga ccagacaaaa atcgtgacga ttatgatcat gaagaagatg gtcctagaaa
     7681 acaacaaaag aatcgaagta gtcaaaatca agtgagaaat caaaagaata gtaactggaa
     7741 taacaacaaa aagaacaaaa aaggcaataa caagaacaac cgtaatcaga ctccaaaacc
     7801 tgttacggag cgtaaattcc atgaattgcc aacagaattt gaatatacag atggtatgac
     7861 cgttgcggaa atcgcaaaac gtatcaaacg tgaaccagct gaaatcgtta agaaactttt
     7921 catgatgggt gtcatggcca cacaaaacca atccttggat ggggaaacaa ttgaactcct
     7981 catggtggat tacggtatcg aagccaaaca aaaggttgaa gtggataatg ctgacatcga
     8041 acgtttcttt gtcgaagatg gttatctcaa tgaagatgaa ttggttgagc gtccaccagt
     8101 tgttactatc atgggacacg ttgaccacgg taaaacaacc cttttggata ctcttcgtaa
     8161 ctcacgtgtt gcgacaggtg aagcaggtgg tattactcag catatcggtg cctaccaaat
     8221 cgtggaaaat ggtaagaaga ttaccttcct tgatacacca ggacacgcgg cctttacatc
     8281 aatgcgtgcg cgtggtgctt ctgttaccga tattacgatc ttggtcgtag cggcagatga
     8341 cggggttatg cctcagacta ttgaagccat caaccactca aaagcagcta acgttccaat
     8401 catcgtagct attaacaaga ttgataaacc aggtgctaac ccagaacgcg ttatcggtga
     8461 attggcagag catggtgtga tgtcaaccgc ttggggtgga gattctgaat ttgttgaaat
     8521 ctcggctaaa ttcaaccaaa atatcgaaga attgttggaa acagtccttc ttgtggctga
     8581 aatccaagaa ctcaaagcag acccaacagt gcgtgcaatc ggtacggtta tcgaagcgcg
     8641 cttggataaa ggaaaaggtg cggtcgcaac ccttcttgtt caacaaggta ccttgaatgt
     8701 tcaagaccca atcgttgtcg gaaatacctt cggtcgtgtc cgtgctatga ccaacgacct
     8761 tggtcgtcgt gttaaagttg ctggaccatc aacaccagtc tctatcacag gtttgaacga
     8821 agcaccgatg gcgggtgacc actttgccgt ttacgaggat gaaaaatctg cgcgtgcagc
     8881 aggtgaagag cgtgccaaac gtgccctcat gaaacaacgt caagctaccc aacgtgttag
     8941 ccttgaaaac ctctttgata cccttaaagc tggggaactc aaatctgtta atgttatcat
     9001 caaggccgat gtacaaggtt ctgttgaagc cctttctgcc tcacttcaaa agattgacgt
     9061 ggaaggtgtc aaagtgacta tcgtccactc agcggtcggt gctatcaacg aatcagacgt
     9121 gacccttgcc gaagcttcaa atgcctttat cgttggtttc aacgtacgcc ctacaccaca
     9181 agctcgtcaa caagcagaag ctgacgatgt ggaaatccgt cttcacagca ttatctacaa
     9241 ggttatcgaa gagatggaag aagctatgaa agggatgctt gatccagaat ttgaagaaaa
     9301 agttattggt gaagcggtta tccgtgaaac cttcaaggtg tctaaagtgg gaactatcgg
     9361 tggatttatg gttatcaacg gtaaggttgc ccgtgactct aaagtccgtg ttatccgtga
     9421 tggtgtcgtt atctatgatg gtgaactcgc aagcttgaaa cactataaag acgacgttaa
     9481 ggaagttaca aacggccgtg aaggtggatt gatgatcgac ggctacaatg atattaagat
     9541 ggatgatgtg attgaggcgt atgtcatgga agaaatcaag agataagatt ttttgctcct
     9601 ttcttaggtg gtgagggacg caagcaaacc gatggtttca ttgcttattt ttgagcctag
     9661 ggtctcaaaa atcccctgtg atgggactga taaatcagtt ccatcacttt caccacggcg
     9721 aaagaagcag atgacttcaa attgaacttc gtttcaattt aaactgaaaa tcaagaagtt
     9781 taaaatagct aggtctgctg gcctagcttt tggttcaaag tagagaaagg aatatcatgg
     9841 caaatcattt ccgtacagat cgtgtgggca tggaaatcaa gcgtgaagtc aatgagattt
     9901 tgcaaaagaa agtccgtgat ccacgtgtcc aaggtgtgac catcacagat gttcagatgc
     9961 tgggtgactt gtctgttgcc aaggtttatt acaccatttt gagtaacctt gcttcggata
    10021 accaaaaagc ccaaatcggg cttgaaaaag caactggtac catcaaacgt gaacttggtc
    10081 gcaatttgaa attgtacaaa atcccagatt tgaccttcgt caaagacgag tccatcgagt
    10141 atggaaacaa gattgacgag atgctacgca atctggataa gaactaaaga agaggggttg
    10201 cccctctttt tcggctcttt gtcaactgta gtgggttgaa gaaaagctaa gctcgagaaa
    10261 ggacaaattt cgtcctttct tttttgatat tcagggcgat aaaaatccgt tttttgaagt
    10321 tttcaaagtt ccgaaaacca aaggcattgc g
//
LOCUS       DAVHSL010000072         9822 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000072 DAVHSL010000000
VERSION     DAVHSL010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9822
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.074"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..215)
                     /gene="blpU"
                     /locus_tag="VVR39_001971"
     CDS             complement(<1..215)
                     /gene="blpU"
                     /locus_tag="VVR39_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6031376.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAA"
     gene            complement(418..708)
                     /locus_tag="VVR39_001972"
                     /pseudo
     CDS             complement(418..708)
                     /locus_tag="VVR39_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(754..987)
                     /locus_tag="VVR39_001973"
     CDS             complement(754..987)
                     /locus_tag="VVR39_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6031377.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(993..1985)
                     /gene="plsX"
                     /locus_tag="VVR39_001974"
     CDS             complement(993..1985)
                     /gene="plsX"
                     /locus_tag="VVR39_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU6031378.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1982..2752)
                     /gene="recO"
                     /locus_tag="VVR39_001975"
     CDS             complement(1982..2752)
                     /gene="recO"
                     /locus_tag="VVR39_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU6031379.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2749..3918)
                     /locus_tag="VVR39_001976"
     CDS             complement(2749..3918)
                     /locus_tag="VVR39_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6031380.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYTPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            4067..5077
                     /locus_tag="VVR39_001977"
     CDS             4067..5077
                     /locus_tag="VVR39_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU6031381.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMSMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(5315..5752)
                     /locus_tag="VVR39_001978"
     CDS             complement(5315..5752)
                     /locus_tag="VVR39_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU6031382.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPVPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5837..8470)
                     /gene="polA"
                     /locus_tag="VVR39_001979"
     CDS             complement(5837..8470)
                     /gene="polA"
                     /locus_tag="VVR39_001979"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU6031383.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8726..9076
                     /locus_tag="VVR39_001980"
     CDS             8726..9076
                     /locus_tag="VVR39_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6031384.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            9291..9407
                     /locus_tag="VVR39_001981"
     CDS             9291..9407
                     /locus_tag="VVR39_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6031385.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            9400..9633
                     /locus_tag="VVR39_001982"
     CDS             9400..9633
                     /locus_tag="VVR39_001982"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031386.1"
                     /translation="MFNQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         2773 a         2426 c         1807 g         2816 t
ORIGIN      
        1 gctgcatagg ccacacctcc aagtatagct cctcccgcag caccagttgc tgcaccttgc
       61 catgttcttg ttttaattcc tagctgaaga cctcgtgctg ctcctcctcc aacacctgct
      121 ttggcaaaat ctccccaatt gcatccgcca ccttcaacgc aagcaagcat ctcagtatcc
      181 ataatttcaa attgtgacat cgtttttgta ttcataacga atacctcttt tttattttta
      241 atatttgtct tgttacaaac ttgacaagtt tagtataaca gtatctatta atttttttca
      301 tccaaatctt gaattggcat cgaaacgtct tgaattagct tttttgtttc aaaatcatct
      361 ctatttttaa aaaagatgtt ttctaatcac ttttttacta ttagacttcc tgcaaaacta
      421 gaatcctagt tcatgattga taataccagc aatcaaattc attcgtaatc cgaagcgttt
      481 acgatgattt cgataggttg ttgaaaacat tttaaacgtt tttactttgg caaagatatt
      541 ctcaaccttg cttctctcct tagatagcgc atgattacag gctttatctt caactgttag
      601 cggcttgagt ttgctggatt tacgtggagt ttgtgcttga ggatatatct tcatgagccc
      661 ttgataacca ctgtcagcca agattttacc agcttgtccg atatttctca tttctaaaaa
      721 ccatctactt ccgttgactt ggaactccga ttgctatttt ccttgaatga ttttaaccac
      781 atctcctacg ttttggagtt ggtcaatttc ttcatcgctg atttcgatac taaattcatc
      841 ttccagagtc aagataaact ccatcaagtc aacagaatcc gcatccaaat cgtctttcag
      901 actcaaggat tctgtcacga caaagtcctc tccctgtcgc tcttggataa tggtcacaat
      961 acggtcaaaa atttcttttt ctgtcatctc ttttattctc ctgaaaattc acgcgcagtc
     1021 tgggcaacta cgtctgtttc tagcatggta cgaatctggc gaatcgtact ataaacagcc
     1081 ttggcatcgc ttgagccatg agtcttgaca acaggtgcct taacaccaaa caagaccgct
     1141 ccaccaacat ctgaataatt gagctgtttt ttcaaacctc tgaggctgtc cttgagaagg
     1201 agggcaccta gtttcgctcg aagaccacca cctgtaatag ctgtcttgag caagcccatg
     1261 attcccatag ctgtcccttc gatggatttg agcacagcgt ttcccgtgaa accatctgcc
     1321 acaacaacat ctgcaacgcc attcatcaaa tcacgcgctt ccacatttcc gataaagttc
     1381 aaactttcat cagccactag taattcataa gtttccttac gaagcggatc gcccttgcta
     1441 ctctctgttc cgttattgag caagccaaca cgtggttgcg caatgccacg aacattttta
     1501 gcatagaagg atcctagaac cgcgtattga tggaggtgct gggctgtatt ttccgcattg
     1561 gcaccgaggt ctagcatgtc aaatcccttc ccatctacag tcggcaaagt cgacataagc
     1621 ccaggacggt cgatattctt gatacgaccc acgatgaaga atccagcagc caacaaggca
     1681 cctgtattcc cagccgaaag gacagcgtct gcttcaccat ctttgacagc cttggctgcc
     1741 aataccatac tggcattttt cttattccta atagctctcg taggttcatc atccgaatca
     1801 atcttctcat ccgtatggat aatgctgacg cgctctgtcg ctgtcagata ttgcttgatt
     1861 ttagcttcat ctccgtaaag ttgaacctcg atatctgaaa agtcagatag ggcttgattg
     1921 acaccctcaa caatggcctg aggtgcgtaa tcgcccccca tggcatctac tgcgattttt
     1981 ttcatttctt ttcctctttt agtaattgtc cccagtctgc tagggaatca ataaatttct
     2041 ttgattttag gtgaatccca acgtactctt catataattg atccataaat tggcgtagct
     2101 cttgcttgat tccaggcttg agcgaaatgg tctccaaagt ctcaaaatca atagcttgaa
     2161 attgattgag cagatagggg atattgggat tgagatgaca acgtctctta tcctcatgat
     2221 aatgctctgg acagaggcag gctccatatt tgaaagaaaa gtcaaaagcc tgaccaaccc
     2281 gatggcagaa gacacactca ttaaaattga ggctgattcc aaatcgagtc aaaatttgaa
     2341 tttcaaaaat attggtcaaa acctgataat ccaagcctgc ttccatcaac tccaaagtct
     2401 tttgcaaaaa agcaaacaag ggagcatcct gctgattgtc ctgcaaacta gcatctgcaa
     2461 gagctgccac ataggtcgca taggccatga caaagaggtc actattaatc ttgggaaaag
     2521 tcatgacctc atgatagtct tcgatgtaac tgagtccgtc atcattgatt cgcaagagaa
     2581 atcgtgccag caccaagggc tgaataacag gcgccagctt agactgacca gcgtgtttga
     2641 caaaaaacat gcgtttgcca acctgctctg taaaaatttt gacgagcttg tcatcctcac
     2701 gaaaattgcg attgtaaagc accaagcctt gactcgtgat agactgaatc atgcttctct
     2761 catgtactcc tcaagtcgtt tcatggcttc tttgatagtc tccatgctgg ctgcataaga
     2821 taggcggacg tagccttccc cgtaacgtcc aaaggctgca ccagggataa aggcaacggc
     2881 cttcttctga gcaaaatcct tcagaaaagc aaaggagtct tgattgtagc ccgctggaat
     2941 tttagcaaaa atatagaagg caccgtctgg tttgataatc tcaaaaccaa gagcagtcat
     3001 tttttcgatg atatagtccc gacgctggat atattccttc ttcatgggct ccgcatcatt
     3061 tttaccagcc gtcaaggctt ctaccgcagc atgttgcgcc atggtatttg cggcagtgac
     3121 caagtattgg tgactcttga ttaactgggc tgtgaaggcc gcaggagcga aaatcagccc
     3181 caaacgccaa cctgtcatgg catgcgattt agacaaacca ttgataataa tagcctggtc
     3241 tctcaacatc gttcctagag acacatgggc ttcgcctgtg taggtcaatt ctgagtaaac
     3301 ctcatcacag acaacaaaaa tttcgtactt gcgtaaaaca gctgccaagg cctctaactg
     3361 ctctcgactg taggtaattc ctgtcggatt ggctggatag ttgagaataa ccgccttgag
     3421 cttatcaccc tgctccaaaa tggccttctc caacatctca ggagtcaaga caaaaccatt
     3481 ttcagtcgta tcaatctcaa caatttctgc cccaactaag ttaacaatcg gttcatagcc
     3541 tggataagca ggagctggca aaagtacctt gtcgccctct tccaaaatag ccgtcaaagt
     3601 cgcagataaa gcctctgtcg ccccaattgt aaccaagatt tcattttcag gagtatagtc
     3661 cagttggtac ttttccttaa caaagtcact ggctgcctga cgtagagtca gcagaccact
     3721 catccctgta tagtaggatt ggttctgatc aatcgctcgc ttggccgcct ccttgacatg
     3781 gtctggcgtt gtaaaatcag gttcccccaa ggtcaaacgc aagaccccag gaatctccga
     3841 aatagcctgg tcaaactgac gaatcaacga aacttgaatt ttatctaact gtttattaaa
     3901 gcgcttagtt aagtccatag atacctccta ctttcaaaac gtatctctat tatactacaa
     3961 aagccccccg accgcaaaaa tacattagag aatagctttc cactttctat tttacttttc
     4021 ctgtttacag gtctataatg gtaacagatt ctatttggag gtttttatgt catttctatc
     4081 aaaaaatgga gcaggcatct tggtctgcct tctcatttct atcgtatctt ggtacttagg
     4141 aggattcttc cctgtgattg gcgcgcccgt ttttgcgatt tttatgagca tgctcctaca
     4201 tccctttctc tcgtcttata aacaactgga tgttggattg acctttagtt ccaagaaatt
     4261 gctccagtat gccgttatct tgcttggttt tggtctcaat atctctcaag tcttcgcagt
     4321 tgggcaatct tcactccctg tcatcctttc caccatttca atagccttga ttgttgccta
     4381 cctcttccag cgcttctttg ccctggatac aaaactggct accttgattg gagtaggttc
     4441 ttctatctgt gggggttctg ccattgcagc gacagcgcct gttatccatg ctaaggaaaa
     4501 ggaagtagcc caagccatct ccgttatctt tttcttcaat gtcttggctg cgctcatctt
     4561 tccaaccctc ggcacctggc ttcatctatc caatgacggc ttcgccctct ttgcaggaac
     4621 tgcggtcaat gatacttcct ctgtaaccgc cacagctagc gcttgggaca gtctctacca
     4681 gaccaatacc ctcgaatccg caaccattgt caaactcacg cgaaccctag ctatcatccc
     4741 catcactctc tttctttcct actggcaaag tcgcgagcaa aaaaataagc aaggcttaca
     4801 actgaaaaaa gtcttcccac tttttatcct tcacttcatc cttgcatcgc tcctaaccac
     4861 ccttctgacc tctctcggtg tgtctagtag tttctttacc cctctcaaac aactctctaa
     4921 attcctcatt atcatggcca tgagtgccat cggtctcaaa actaatctgg tcgctatggt
     4981 caaatccagt ggaaaatcca ttgttctcgg agccgtctgc tggattgcca tcatcctcac
     5041 cagccttggt atgcagaccc ttatcggcat tttctaatac tcttcgaaaa tctcttcaaa
     5101 ccacgtcaac gtcgccttgc cgtaggtata tgttactgac ttcgtcagtt ctatctgcaa
     5161 cctcaaaacg gtgttttgag ctgacttcgt cagtcgtatc tacaacctca aaacagtgtt
     5221 ttgagcagcc cgcggctagt ttcctagttt gctagtttgc tctttgattt tcattgagta
     5281 taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc aagcgagtat
     5341 gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca cgcaaaatct
     5401 ctttcgcttc taaactttca agtcctagct gtgcccaaaa aatcttggca tcagctttga
     5461 gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg acaatatcta
     5521 caggaacagg aatttcagcg aggctagcat aagccttttc acccaagatt tcgccacctg
     5581 ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc tttgttactc
     5641 gattgctggt tgtttcttca cggtcagaca aacccaccac agcaagggtt ttactcgttg
     5701 cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc atagaaatcc
     5761 tcctttttca tcagtatagc acattttgaa aaggtttgca gaattctact acaaaaaagg
     5821 aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc tcatctgcga
     5881 taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat ttttttatct
     5941 ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt aacagcatct
     6001 tagtctgata accacctgca accaaggctt tatccagctg aatcatggca atcttgagaa
     6061 tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca aaaccacgaa
     6121 tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag agggtctcta
     6181 catagccctt atcacgcgcc tcccgcacca cttcatccat gtagttttta atacctggaa
     6241 aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt cccaaattat
     6301 tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc ttggcattgc
     6361 gacggtcatt tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc atggctgtcg
     6421 aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc ttagaaatat
     6481 gcgccaaaac gcgcaattca atctgtgaat aatcagagct gagtagcaca ctatcctccc
     6541 actctggcac aaaagccttc cgaatcaagc gcccttgttc caatcgggca ggaatatttt
     6601 gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc acatagcgag
     6661 tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa gtagattgaa
     6721 tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata ggagcgagac
     6781 gctccaaaac atccactgct gtcgaataac ctgtcttggt tttcttagtg tattctagag
     6841 gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg acattaaact
     6901 cctcaccggc cagctcgtaa atctcttgag tcagtttttc aatgacaagc tcattttcag
     6961 cctgcatctc aagcaaggtc tctttcttga ccataatccc agcaatttcc atcttggcaa
     7021 ggacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca ttttcgctga
     7081 gtttttcaag taaaataggc tctgtttcta ccaaaacagc aagtttacaa gctaagtgtt
     7141 ccaagaattt ctcacgttca ggaatggcct ttttaacacc cttaccgtag aaagtttcat
     7201 catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca ttgtcctcca
     7261 cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc aaatccacac
     7321 caaaacgctg caaaagaact ttaaccttct taaagtcata aactctcaga gatgtttttt
     7381 ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg gcatagagct
     7441 tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc tcaccaaaaa
     7501 gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg tcaacaatag
     7561 taaaatccaa accctcagcc acatcagctg acgacacatt taaagcctgc ttgagctgtt
     7621 tgaatcccat ctcatcgtaa aatttcccaa gattttcaac atctggacca ctatagacca
     7681 agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt gttttagaca
     7741 aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc ttcattccat
     7801 caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta atacccgtct
     7861 tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg agcgccttga
     7921 gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct ggcgtaaagg
     7981 cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca tccgtcagct
     8041 gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc tctgctagct
     8101 tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag tgacgaatcc
     8161 ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca tcaggagtct
     8221 tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc tttcccgcat
     8281 caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc aacatcaact
     8341 gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg tccaactgct
     8401 gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat aataattttt
     8461 tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg aagagctaga
     8521 gcaagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt tagtaaacct
     8581 agatttaaaa atgtgctata atatagtata ttgaatctat aatagtacac cttgactgct
     8641 aaaatatttc tataaattaa tttgactttc ctgatagagt tattcacatc ttatttcaac
     8701 tcactataga aggaggaata ggaggattct cagacatccg ggcatcagcc caactaatga
     8761 tttgattgct aagaaaatat tcagcaatcc agaaatcact tgtcaattta ttcgcgatat
     8821 gctggacttg ccagcaaaaa atgtgaccat tttggaggga agcgatattc acgtattact
     8881 ctccatgcct tactcggtgc aggattttta taccagtata gacgtcttgg cggagttgga
     8941 taacggtact caagtaatta ttgagattca agtccatcat cagaattttt tcatcaatca
     9001 cttgtgggct tacctgtgca gtcaggttaa tcaaaatctt gaaaaaattc gtcagcgaga
     9061 aggtgatact cactagagct acaaacacat cgctcctgtt tacgccattg ctatcgtgga
     9121 tagtaattat ttctcagatg acctggcttt tcatagcttt agtatgcgcg aagacacaac
     9181 aggtgaggta ttggcgatta ccaacaatgg acaggaaaac catctggtta agatggcatt
     9241 cttggaatta aaaaatacag agaaaccagc aaagacaagg ttcgcaagcc atggttggag
     9301 tttttcggca acaagccctt tacccagcaa ccgcaacgag ccattaccca agcaaatcaa
     9361 ctgctggact acaagagctg gtccgaggag gacaggaaaa tgtttaatca actacatatg
     9421 cgagaagaac aagtcttgtt agcacaggac tatgccttgg aaactgctag ggctgaaggc
     9481 cttgaacaag gactagagcg tgggaaagtt gaaggaaggg cagaaaggaa actttttgcc
     9541 ttcctagaca tagtacgcca aggtcttctg acttctgagg ttgccagcca gcaattaggt
     9601 atgtcagtat ctgaatttga ggcactgttg taaaatggct ccataatatc catagtgggt
     9661 aaatccccta tggatattat ggagcctatt ttgtgtagaa aaaaagtccc atatgaccta
     9721 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
     9781 acaaaattac tagacattaa agaccctaat gtccagattt ta
//
LOCUS       DAVHSL010000073         9726 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000073 DAVHSL010000000
VERSION     DAVHSL010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.075"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            190..285
                     /locus_tag="VVR39_001983"
                     /pseudo
     CDS             190..285
                     /locus_tag="VVR39_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(538..1158)
                     /locus_tag="VVR39_001984"
     CDS             complement(538..1158)
                     /locus_tag="VVR39_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6031387.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1158..1640)
                     /locus_tag="VVR39_001985"
     CDS             complement(1158..1640)
                     /locus_tag="VVR39_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU6031388.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1640..2482)
                     /locus_tag="VVR39_001986"
     CDS             complement(1640..2482)
                     /locus_tag="VVR39_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU6031389.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVDYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2577..3377)
                     /locus_tag="VVR39_001987"
     CDS             complement(2577..3377)
                     /locus_tag="VVR39_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU6031390.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3521..4900
                     /gene="glmU"
                     /locus_tag="VVR39_001988"
     CDS             3521..4900
                     /gene="glmU"
                     /locus_tag="VVR39_001988"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU6031391.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRSRQINKDEYAT
                     RLPHHPKNQ"
     gene            4910..5455
                     /locus_tag="VVR39_001989"
     CDS             4910..5455
                     /locus_tag="VVR39_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6031392.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5467..5781
                     /locus_tag="VVR39_001990"
     CDS             5467..5781
                     /locus_tag="VVR39_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU6031393.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5798..6490
                     /locus_tag="VVR39_001991"
     CDS             5798..6490
                     /locus_tag="VVR39_001991"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU6031394.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6567..7058
                     /gene="rocS"
                     /locus_tag="VVR39_001992"
     CDS             6567..7058
                     /gene="rocS"
                     /locus_tag="VVR39_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU6031395.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7156..7746
                     /locus_tag="VVR39_001993"
     CDS             7156..7746
                     /locus_tag="VVR39_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU6031396.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7755..9518
                     /locus_tag="VVR39_001994"
     CDS             7755..9518
                     /locus_tag="VVR39_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU6031397.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3016 a         1685 c         2073 g         2952 t
ORIGIN      
        1 aagacttttt gaccagcctc atttttttaa cttgatactc agtgaaaagc aaagattaaa
       61 ctaggaagct agctgtaggc tgctcaaaga acagctttga ggttgcagat aaaacttgtg
      121 aggtaaccaa catatataat gtgaagctga cgtggtttga atagatttta gaagggtatg
      181 agtctggaag ttttaatgga taatgcaaga ttccatagaa tgggtaagct agagttctta
      241 tgtgaagagt ttgggcataa acttttacct tttcctccct actcatctta gtatagaaaa
      301 gtgaatctaa aatagtacat aactgcttct aaaacattct tataaattga tttaaattct
      361 caaatcatat tattcagttc ttatttcatt ttgctctaca atcctgttga gaagacacgt
      421 gttcatatca aaaaggtatt ggcaagttgc aatacctttt tacaaggttc ttttgtctta
      481 tttttgtttc aactgactat atctcctatg gttctagttc agaaggctag gctataatta
      541 tgattgataa gaagtatcat tccaagtatt gagagtgaat gtttcaaaat catgggtttc
      601 tataatggtc aggctggcat ttgctagacc gccatcttta cgaagaagtg gttctttata
      661 gcctaggaga gtacgaagac tggcagtaag attggcgccg tgtccgacaa ttagaatacg
      721 ctcagctgga ctatctttta atgatttgat aaattggatg gtccgctgag ttgtactata
      781 gagggattcg gctccgaaca ttcgagtgtc aaattgagca agatttgaac gaaaagcctg
      841 gatttgttgc gggtaaatag cttccagggt tgcaattttc aaaccttcta acttcccaag
      901 ttgccattca cggagattag gaacgatttc taaagaacag ggggtatgga gttgactttg
      961 gataatctca gcagatttga ccgctcgagg taaatcactt gaataaatct gatcaaaagg
     1021 aatttccttg agatactggc caagtcgttt tagggtttca atggattcag gaagaagagg
     1081 agaatcaccg ctagcacctt gaaaacgacc ttcttggttc cagagggtac gaccgtggcg
     1141 gacaaagtag agtttcatta cttgatgtcc tccaaaatat ctacaaagtc tgcctttaca
     1201 aagctagcca agtcttgtgg cgcgacgata atgctgtgtc cgacttcgcc tgcagagaca
     1261 atcattcgat ccaaatctag agcaatttta tcgataaaaa tgggataatt gtgtttctga
     1321 cgaattccga caggattatt ggctccatga atgtaaccag ttgttttttc taagtccttt
     1381 tgtggaatca tgctcacttt tttattgcca gaaattttag ctagtttctt ttcagacaag
     1441 tgctgagtga tagggacaat tccgataatc ggtccggtct tgtctcccaa aagcgccaag
     1501 gttttgaaaa tctgatctcg ttcataacct tgaggaagct ctccttctag ggcattgatt
     1561 tgaatcccct gatgagggat agctgcttta gataggattt gttccaccaa tgtttttttg
     1621 attttaactt tttttgccat tatttatatt tatcctccaa ttgactcatc caaataccaa
     1681 gccagattcc cagcgcaaag aagaaggcga tgatgacata atcgacaagt gaaagtcctg
     1741 tgtattggat actttcagcg tttcctgcat ttggaattaa gatcaaaagg gtacttgata
     1801 ggacgatacc gatgatgaaa tgatagacgc gtgagtggta gttgtttaag gcataatcca
     1861 tcaattttga aaaaacgatg agagttgcac ctgcaccaat tccaatcgga aagaaggttc
     1921 ccaagaaatc aaaagtttta aaaccagtca acataggagc atagagtccc aaaatcaaaa
     1981 gtaaatttga tgggctgagg ccaggaacca agacgccaag ggccaatagt gcgcctgcta
     2041 ggacgaagtt aagaaagctg gcgcttaagg ttccaacgac aaaatttaag gcatagagtc
     2101 ctaatccaga aatgataaag gttgtccata accaagctaa atcaatcttg tctcggtcag
     2161 attctcgagt tgattctttg aggaggctag gaactgtacc gataatagct cccgcaaagc
     2221 tccataatac aaaaacctga taattttcaa gcaggtattc aatcgggtag gaaaataagc
     2281 cgattcccag aagcataccg atggcaactg gaataaagta caaaacattt tctttaaagt
     2341 ctttaaaggg atgggccaga aagccaatca ttcgttcata gattcctaag attgctgcta
     2401 gaacccctcc ggaaattccc ggtaggataa atccaagagc aattacaatc cctttaataa
     2461 cgcgtgctaa ccatgagagc atatatttcc tccaactatt tctatttcaa aaaatcctta
     2521 ctatattgta tcacaatcag acacaaaaag aaaaagcaaa tgataaacaa atgcttttaa
     2581 ggttttaaaa aaagttttcg aaaggtttct tctttatttt ttaagggaga gataacgttg
     2641 atatctaaat cgtggtcaaa gccggcaatt tttcctttag atgtgtattg gtgaatatca
     2701 taatctaaat cagttttagg actgctctcc aaaaatcctg agtctgagcc gtaggacgga
     2761 atccaaacag aggtaaactt gcctgtatca atactgtgtt cttccatgaa gtagacacca
     2821 acgtagatgc cgatgttttt agcacctagt gatgctagtt ttgctcgaaa gttttcgaca
     2881 ccttcgttca tattagacat ggttttgtct tccacgtcaa gccaatagta actagggctg
     2941 taaggagagg cagcattgta gaaaacttcg gcagcctttt ccatttcttg gacacttttt
     3001 ccagctacat aagcgtagac agcaactggg acattccgct tttgaagttc agtgatatga
     3061 ctcttatagg ccttgtctat tccattgata aatgaagcat cattttcttt tgttgtttga
     3121 gcaccactgt gaacacgaac aatagcacct gaaatatttt gtgagagggc atcgtagttg
     3181 atttcctcag gacgctgcca gccagagagg tcaataatcg gtttgtctaa gtgtttcaaa
     3241 gcctgtgctt caatctgtgc tatattggat tttgttttaa acgattggct gtcattaagt
     3301 gggcgattga tgattaaaat gaacatcata atcccaaaaa aactaaataa aataagtgga
     3361 tgaatttgtt ttctcatatc ttataagtct accctaaaaa tcaaaaaaaa tcaaaaaaat
     3421 gggttaagga agagacttta gagcattttt tcattcaaga gtgcggaatg atttgaaata
     3481 tggtataata aaagggaatt tctacagaaa agagaagatt atgtcaaatt ttgccattat
     3541 tttagcagcg ggtaaaggga ctcgcatgaa atctgatttg ccaaaagttt tgcacaaggt
     3601 tgcgggtatt tctatgttgg aacatgtttt ccgtagtgtg ggagctatcc aacctgaaaa
     3661 gacagtaaca gttgtaggac acaaggcaga attggttgag gaggtcttgg ctggacagac
     3721 agaatttgtg actcaatctg aacagttggg aactggtcat gcagttatga tgacagaacc
     3781 tatcttagaa ggtttgtcag gacacacctt ggtcattgca ggagatactc ctttaatcac
     3841 tggtgaaagc ttgaaaaact tgattgattt ccatatcaat cataaaaatg tggccactat
     3901 cttgactgct gaaacggata atccttttgg ctatggacga attgttcgta atgacaatgc
     3961 tgaggttctt cgtattgttg agcagaagga tgctacagat tttgaaaagc aaatcaagga
     4021 aatcaacact ggaacatacg tctttgacaa cgagcgtttg tttgaggctt tgaaaaatat
     4081 caataccaat aacgctcaag gcgaatacta tattacagac gtcattggta ttttccgtga
     4141 aactggtgaa aaagttggcg cttatacttt gaaagatttt gatgaaagtc ttggggtaaa
     4201 tgaccgtgtg gcgcttgcga cagctgagtc agttatgcgt cgtcgcatca atcataaaca
     4261 catggtcaac ggtgttagct ttgtcaatcc agaagcaact tatatcgata ttgatgttga
     4321 gattgctccg gaagttcaaa tcgaagccaa tgttaccttg aaagggcaaa cgaaaattgg
     4381 tgctgagact gttttgacaa atggtactta tgtagtggac agcactatcg gagcaggagc
     4441 ggtcattacc aattctatga ttgaggaaag tagtgttgca gacggtgtga cagtcggtcc
     4501 ttatgctcac attcgtccaa attcaagtct gggtgcccaa gttcatattg gtaactttgt
     4561 tgaggtgaaa ggatcttcaa tcggtgagaa taccaaggct ggtcatttga cttatatcgg
     4621 aaactgtgaa gtgggaagca acgttaattt cggtgctgga actattacag tcaactatga
     4681 cggcaaaaac aaatacaaga cagtcattgg agataatgtc tttgttggtt caaattcaac
     4741 cattattgca ccagtagaac ttggtgacaa ttccctcgtt ggtgctggtt caactattac
     4801 taaagacgtg ccagcagatg ctattgctat tggtcgcagt cgtcagatca ataaagacga
     4861 atatgcaaca cgtcttcctc atcatcctaa gaaccagtag gagcctatca tggagtttga
     4921 agaaaaaacg cttagccgaa aagaaatcta tcaaggacca atatttaaac tggtccaaga
     4981 tcaggttgaa ttaccagaag gcaagggaac tgcccaacgg gatttgattt tccacaatgg
     5041 ggctgtctgt gttttagcag taacggatga acaaaaactt atcttggtca agcagtaccg
     5101 caaagctata gaggctgtct cttacgaaat tccagccgga aaattggaag taggagaaaa
     5161 cacagcccct gtggcagctg cccttcgtga attagaggaa gaaacagcct atacagggaa
     5221 attagaactc ttgtacgatt tttattcagc tattggcttt tgtaatgaga agttaaaact
     5281 atatttagca agcgatttga caaaagtgga aaatccgcgt ccgcaggatg aggatgaaac
     5341 cttggaagtc cttgaagtga gcttagaaga agcgaaagaa ttaatccaat caggtcatat
     5401 ttgtgatgcc aaaacaatta tggctgttca gtattgggag ttgcagaaaa aatagaggag
     5461 gtcagtatgg gtaaatcttt attaacggat gaaatgattg aaagagctaa tagaggcgaa
     5521 aaaatttcag gtcctccttt gctagatgat aatgaggaaa ctaagatttt accaacctct
     5581 tcttcccgtt ttggttatgc caatcctaag gatcatggtt ttagccagga aaccttgaag
     5641 attcaggtcg aaccatctat tcataaaagc cgtcgtattg aaaataccaa gagaaatgtc
     5701 ttcaattcta agttgaataa aatcttattc gcggtcatct ttctcttgat tttgcttgtt
     5761 ttagcaatga aacttttgta atagaaaagg aattgaaatg aaaataggaa ttattgctgc
     5821 tatgccagaa gaactggctt atctggtcca gcatttagac aatgcccagg agcaagttgt
     5881 tttggggaat acctatcata caggaaccat tgcttctcat gaagtcgttc ttgtagaaag
     5941 tggaattggt aaggtcatgt ctgctatgag tgtggcgatt ttggctgatc atttccaggt
     6001 ggatgccctt attaatacgg gttcagctgg ggcagtagca gaaggtatcg ctgttgggga
     6061 tgtcgtgatt gctgacaaat tagcctatca tgacgtggat gtcacagctt ttggctatgc
     6121 ttatggacaa atggcgcaac aaccgcttta tttcgaatca gacaaaacct ttgttgctca
     6181 aatccaagag agtttatctc aattggacca aaactggcat cttggtttga ttgctacagg
     6241 agatagtttt gttgcaggaa atgacaagat agaagcgatt aagtcccatt tcccagaagt
     6301 tttagccgtg gagatggagg gggcagctat tgctcaagca gcgcatgccc tcaatctccc
     6361 agtcttagtc atcagagcta tgagtgacaa tgccaaccat gaagcaaaca tcttttttga
     6421 tgagtttatt atcgaagctg gacgtcgctc tgcccaagtc ttgttgacct ttttgaaggc
     6481 tttagattaa gcggaaattt gacagttttt ctagcttatg ataagattta agtaaagaaa
     6541 agctagaaaa cgtttcagag gatattatga gtattgaaat gaccgtcagt gagattgcag
     6601 aggtcttagg attatctcgc caagcaatca ataaccgtgt caaagaatta ccagaagaag
     6661 acacagataa aaatgacaaa ggggtaacag ttgttaccag aagtggcttg attaagctag
     6721 aagaaatcta taaaaaaacg atttttgaag atgagcctgt cagtgaagat gtcaaacaac
     6781 gtgaactgat ggagattcta gtggatgaga agaatgcaga aattcttcgt ctttatgaac
     6841 aattaaaagc caaggatcgt cagttatcag aaaaagacga gcagatgcgt atcaaagacc
     6901 gtcagattgc tgagaaagac aaacaattag atcagcaaca acaattgacc cttcaagcca
     6961 tgaaggatca agaaaatctt aagctagagc tggaccaagc aaaagaagaa gtccaatcca
     7021 ctaagaaagg cttttttgct cgtttatttg gaggataatc aaggagctgt ttaggttaaa
     7081 tgctaacctg atggcttctt ttgtttgtga atagtatagt tgattagaac agagacagta
     7141 gaggagaggt acagaatgga acgattagaa gattacattg cttttgactt agaatttaat
     7201 cagcacgaag gacaaacaca cttgattcaa gtatcggcag tgcgttttag agatggtcgg
     7261 gaaatcgatg cctatgattc ctatgttcat accagcgtcc ctctaaaaag ctttatcaat
     7321 ggtttgaccg ggattacagc tgagacctta aaagatgctc ctccagttga gaaagtctta
     7381 gaagaattcc aagagtttgt gggttctttg ctgatgatag gctacaatgc tgctaaaagt
     7441 gatttaccta ttttagcaga gcatggttta gactatagcc aacagtacaa ggtggatttg
     7501 tatgatgaag cttttgaacg tcggagttca gatttacatg gtattgccaa tctcaaattg
     7561 caaactgttg cctcatttct tggatttcaa ggtcagtctc ataatagttt agaggatgct
     7621 cggatgacgg cgcgtgttta cgaatccttc ttagagtcgg atcaagctag ggaattgtta
     7681 gagacagaaa gtagcttatc aaacaatcct tttggtggct tggacttgtc tcaattattt
     7741 gactaggagt gcctatgaaa cctgaaaaac ctaaaaaatt gggtcttaaa cagatttacc
     7801 tcaatcttga taaaatcctc tttctatttt tcttgatttt tatgatagtg gagtatttgt
     7861 gggtaccatt caattcatgg ttggctagct tcttattaga tcagacaggt tatcttttta
     7921 tttcctataa caatgtctta gccatcctta ctcattctcc attgattagt ctagcttttt
     7981 tagccttgat tgtaattaac cttctggttg cttattttca aataggactc ctctttattg
     8041 gtgctcgtca tctcctctat aatgaaaagc gaaggctaat tgagtatatc cgcaaggttt
     8101 tccatgaaag ttttggattt atgaaaaagc taacttgcgc taaagccttg tttatctttt
     8161 tctatatagc tatgcttttt ccttttatac ggaaaatgct gaagatttat tatcttaata
     8221 aaatcgtcat cccagagttt atccaagctt atttagaaga taaatattgg atgtggtggc
     8281 tgagcatcct acttctatct cttatctttc tctatgtctc tgtcagattg atgtttgccc
     8341 ttccgaagat tgtatatgat cagctgactg ttcgagaagc agtgatgttt agcttggaga
     8401 aaaccaagaa gagagttact ttttatgctt ggaatttatt ttacatcttg ctcaaagcac
     8461 atttattatt ttatcttcct ttgattcctt tattattggc tcaaactttg gtagatgata
     8521 tcactcagag agagtctctg attcttggta ttttgaattt tgtcgtgatt aaaaatctct
     8581 attatatggc tctgacttat tttttggtta aatttgtttc atttttgaca ggaaaggagt
     8641 tggatatgct tcctaggaga gaaaaagatc acatcgtgcg atggggtgtc atgacttgtg
     8701 ccagtctttt ctttgcctta gaaggttata tttatctgga ggctcccatg gttcatctac
     8761 ctcaacttat ttctcaccga ggggtttcca atgcaaatgg gattcaaaat acagtagagt
     8821 ccttggaaac tacagcacaa ctcaaaccag acttggtgga gacggacgtg caggaaacaa
     8881 aagatgggca gtttgtcatg atgcatgatg ctaacttgaa aaatttagca ggtatcaata
     8941 aaagtcctca agacttaaac ttggaggagc ttaaagggat tgatattttt gaaaatggct
     9001 accagactaa aatttcaagc tttgaagatt atctcagtcg agccaacgaa cttggtcaaa
     9061 aattactaat tgaaattaaa accagtaaaa aagatagtcc agacatgatg aaccgctttt
     9121 tagcccgtta tgctgcaaag ctcaagattt atggacatca aatccagtct ttagactacc
     9181 atgttgtcga aaaagtaaga cagtatgatg ccgaactgcc agtttatttc atcatgccct
     9241 acaattctgt ctttcctaaa acaagagcga caggatatac tatggagtac tcaaccttgg
     9301 atgaatattt tgtaagcaaa ctatggacaa cggatcagaa actttatgtc tggactgtca
     9361 atgattcaga agctatcagc aaatctcttc acttaggagt agatggagtg attacagatg
     9421 atttggaaaa agttcagcgg gaaatagaag tagcccaaga agatccagaa tatacggatt
     9481 tgctcttgaa aaaagcattg gaattctttg aattttagta ataaaaaaga ggaacggttg
     9541 ttcctcccat gataggtaag tattcttgtg aatgcttgct tttttgtggt tgcaatccgt
     9601 ttacgagaat tgtttgtatt gttcttgttt caatttactt tatagtgctt tgaagttgga
     9661 atgctacact ataacttcta aaatatagta aaatgaacca aaaatagtac acaatgtggt
     9721 ataatc
//
LOCUS       DAVHSL010000074         8538 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000074 DAVHSL010000000
VERSION     DAVHSL010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.076"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            39..167
                     /locus_tag="VVR39_001995"
     CDS             39..167
                     /locus_tag="VVR39_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RiPP precursor"
                     /protein_id="HEU6031398.1"
                     /translation="MKYCKPTFESIATFKKDTKGLWTGKFRDIFGGRAIVRIRIEF"
     gene            284..2008
                     /locus_tag="VVR39_001996"
     CDS             284..2008
                     /locus_tag="VVR39_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase"
                     /protein_id="HEU6031399.1"
                     /translation="MVNKYFFEKYSDKKIVFLTKNLYRTVSGENKKIYCLEDYVEGVC
                     SIIEQNDISSFEEIILALQDYVTNGLIIVEMTERTYIISPYLDSRLSWFENNKNIIFS
                     DSSVEIAKYLNLKLSTKRLASQFIFGLPYYPFQTISLWEELVNIRPLNYLEISEKGCL
                     EKRVPSYEVDTKDFNKLIIKIKEEFLNSINHDLNMRNEVSSDVSGGVDSATIAFTLNK
                     LIPDFSILHAESSTTANSDTKWATFIAKSLGRELKKFDSIEITEKRFAIDEKYINDIM
                     PSSPLLWADSEGYLKSVIGYQKGRKQPTHFLGIGGDELFTPMPSNSWNIVRQENLGGL
                     LYALKYSLIMRRPFFSCLLDLLDNRGYSETVIKNLEIVFNESSAPIKRELGWVDGLQV
                     PDWLSEKSKQESQIFLNSLLFSNSEPIISDRTAFQMIQSLIFQKSVLRQIQLTTNSIY
                     WATPFLHKKLIEICLQIPAKYKVSSKLTKPILQKALKGIVPIEVFNRGFKGDYSDALY
                     SGYREAVRKNFHNLEQFELVKMGIIDVEKLKLEMSLPAGNPSKIDYFEKLCSVERWIR
                     QIKLYMKN"
     gene            2023..2274
                     /locus_tag="VVR39_001997"
     CDS             2023..2274
                     /locus_tag="VVR39_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HEU6031400.1"
                     /translation="MFNKESKSRLKIIKQDTGAIVFDKNQGIYFQTNDVGVKILELLS
                     KNESEEEIVSAISVAYSIEIDVAKQDVKDFIQSLKKGGL"
     gene            2278..4500
                     /locus_tag="VVR39_001998"
     CDS             2278..4500
                     /locus_tag="VVR39_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="HEU6031401.1"
                     /translation="MDMQLNQESYSYVQLKYRLLAQIALLISYPLTKFSPKRIELLIN
                     KLSNSKLSATENEAILARDAICTVSHKCRNQDGCVKRSLGVIMFLLLLNKRASWCTGF
                     AMNPFRSHAWVEVNGNPIKELEEVSSYERVVKTLDDKNEERKHMISENIEKVDDTMTN
                     VKFRDLLVLIENKRKYFLIVLCLGILTSILTLLQPELLSKVISQKGVNLFNNPTIYML
                     ITITVGSTIISSLQYYFLQLMGESAVFQSRKNLIIQFLKLPIYKYNDLSAGDLISRFS
                     SDTSKLRAGIIQSTVALTSGLFLSLGAIFTLFLKDTYLAIITIISIALSFLFILLMSS
                     LIQTASYKAHQGLGKMTAYLNRLIVGIRTIRSTNETNSELSKMLSEVQEVKNLGIGVA
                     RVQSIMTPISNFSLQLCGIIILGIGGYRVSTGQMSIANLTSFMLLMYIAISPVGQIFS
                     SVTTISEALGALSRITEIIDLPKEEDNDIILNLESKSDRSKAIEFVNVTFSYDSYQFQ
                     DIQSDDNYILKDITFEINSGDYVSIVGPSGAGKSTLLYLIERFYDTTSGGIKIFGQDF
                     RTISRETLRSNISYVEQNSPLVAGTILENLKMGNSNVTYDECCDALEKVGLEHLIQRG
                     ASGIESPISEGGFNLSGGERQRLAMARAILSDAKILLLDELTSNLDSLSEKKMKEAIK
                     SMRGERTIIMVAHRLSTILDSDEIFVLEHGRIVGNGTHMELLESVPLYKELAKEQFLV
                     "
     gene            4513..5229
                     /locus_tag="VVR39_001999"
     CDS             4513..5229
                     /locus_tag="VVR39_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6031402.1"
                     /translation="MTNKIEIRNVTKTYKDGDILKNVSFTAEEGEVTAFLGPNGAGKS
                     STLRILLGLDRSSLGTALIGGKKYCDIERPLLTVGASFDGVGAPSDRTVFQHLKIAAA
                     SNGIGFSRISEVLSITDIEHKRYSKISNLSLGEGQRLGIATALLGNPQYLILDEPTNG
                     LDPSGIRWFRNFIREQASTGKTVLLSSHILSEVEAVTDKVVFIDKGSIIASGTLHNIM
                     NGFDNLEDVFFHLTGGDYDK"
     gene            5219..6010
                     /locus_tag="VVR39_002000"
     CDS             5219..6010
                     /locus_tag="VVR39_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031403.1"
                     /translation="MISSIKSHNILSELYKIFYSRSTQIVLPIVFILQPLLSYISSKQ
                     ILTVGLNATPETNSSLAESIPPIEYIGFDAILLGLFAMIILGAIIGSMEYKNSSLRTS
                     LLLCSNKAVFFVIKFFVTSVFIFVVSCVSIYLSIASAQFGLGREGLNPLILSNNVWYF
                     ILLGSLSWSLLTVLSYSIAFYFKSSLGSLLFLLPQVYNLGSFLSDRIQLAKYLPVSLG
                     QDLIATSPLKITTPGRSVLFLSIWVLVISSFAYYKFLKKDVGNVI"
     gene            6007..6714
                     /locus_tag="VVR39_002001"
     CDS             6007..6714
                     /locus_tag="VVR39_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6031404.1"
                     /translation="MNSFRSEYLKFIYNKWLLLTVLATIILVPLFVIFLHETPSYITE
                     DYVLTQILESFYLGQAGIIIIIILFIGQEFNGSTLRSSLLANPTRWKFFFIKLIVILS
                     ISILVWTLVAFCTICVVYIFYGLLIPLLIYTFTLRIILVSIGLILICFSLVIITRSIV
                     VPMGMSLSFLLGLGQMLLQFSDAFLYFPIISTMNSFLMTENQSYIPYTIGIAIQFLWG
                     ILLLSFSILLFWKRIVR"
     gene            6745..7428
                     /locus_tag="VVR39_002002"
     CDS             6745..7428
                     /locus_tag="VVR39_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6031405.1"
                     /translation="MKEKKVYQILAIDDDESILRLIKNSLERSEFEVTTRREVGNIDI
                     CSFIGFDLILLDIMMSIDGLEICKSIREQIDVPIIFVTAKQLDSDLASGVKAGADDYI
                     KKPFSITELVARVRMHIQREERNRKNNKEICTKNLIINVSNQEILIEEETISLTKREF
                     TILYTLASNPKRVYSVEELYERIYPSESDAQFRSIAEYIYQIRSKLKPYSINPIKTQW
                     GGGYSWNEN"
     gene            7413..8510
                     /locus_tag="VVR39_002003"
     CDS             7413..8510
                     /locus_tag="VVR39_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6031406.1"
                     /translation="MERKLDFKTLVKKTKWTIVKQFCLNIIVAYIFPISTISIDIHSE
                     TQSIARDLLGVLFNVFSWVYICISLIIIVSINIKALLTRVKQEMEIVYHSSIWLTSVN
                     DSSNLTILEFIETNRHIESMQQRIKNMIQVEKDQKADILFKVSAMAHDLKTPLTVIKG
                     NSELLQLAPLSGIDVQCLKDIERASNQLNSYFNQLINYSKTFYSDQISFHQYRISNLS
                     KILEQECTYLIGDSIDYKYSTKIDRDCNIELDLDLIIRSVANIVNNAIAYADDAKKKI
                     RVTFELADSNITLSIWNNGSKFSDDVLENFGKLFYREDTSRNSQFEHFGIGLAFVKQV
                     MSIHSGDIQLQNKENGAMVKLIIPMKSSDYV"
BASE COUNT         2980 a         1086 c         1570 g         2902 t
ORIGIN      
        1 ggttctggca ttagtataaa tgatagaagg agtttaagat gaaatattgc aaaccaacat
       61 ttgaatcaat tgcaactttc aaaaaagaca ctaaaggtct atggactggt aagtttcgtg
      121 atatctttgg tggacgtgca attgtaagaa ttagaattga gttttaagct tataactatg
      181 tattacaatg gtaaataatt ttgaataaag tattttgata ttcattccag aactacgaat
      241 atcaagatgc tttgtttttt tatttctgag gttgttaata tatatggtaa ataagtattt
      301 ttttgaaaaa tattctgata aaaaaatagt attccttact aaaaatttat atagaaccgt
      361 ttctggagag aataaaaaaa tctattgttt agaagattat gtcgaaggag tatgctcaat
      421 tatagaacaa aatgatatta gtagttttga agaaataata ttagcacttc aagattatgt
      481 tacaaatggt ttaattattg ttgaaatgac tgaaagaaca tatattattt caccttattt
      541 agattcaaga ctgtcttggt ttgagaataa taagaatata atttttagtg attcatctgt
      601 agaaattgca aaatatttga atttaaaact ctctacgaag cgtttagcaa gtcaatttat
      661 ttttggactt ccatattatc catttcaaac aattagcctc tgggaagagc tagtgaatat
      721 aagaccttta aactatttag aaatatctga aaaaggttgt ttagaaaaaa gagttccgag
      781 ttatgaagta gacacaaaag attttaataa actaataata aaaataaaag aggagttttt
      841 aaatagcatt aatcatgatt tgaatatgag aaatgaagtg tcgagtgatg tatcaggagg
      901 tgttgattct gcaactattg cttttacatt gaataaactg atacctgact tctctatttt
      961 gcatgctgaa tcaagtacca ctgctaatag tgatactaaa tgggcgacat ttattgctaa
     1021 aagtcttggt agggagttga aaaagtttga ctcaatagaa ataacagaaa aaagatttgc
     1081 gatagatgaa aaatatatca atgatattat gccaagttct ccgttattgt gggcggattc
     1141 agaaggatat ttgaaatcag tgattggtta ccagaaaggt agaaaacaac cgactcactt
     1201 tctaggtatt ggtggtgatg aattatttac accgatgccg tctaattcct ggaatattgt
     1261 tcgtcaggaa aatttaggtg gactacttta tgctctgaaa tatagtttaa taatgagaag
     1321 accatttttt agttgcctat tggatttgtt agataataga ggatattcgg aaactgtgat
     1381 caaaaattta gaaattgttt tcaacgaatc ttctgcacct atcaagagag aactgggatg
     1441 ggtggatggt ttacaagtac cagattggct cagtgaaaaa tccaaacaag aatcgcaaat
     1501 ttttttaaac tcgttattat tttccaattc tgagccaata atatctgata ggacagcctt
     1561 ccaaatgatt caatccttaa tatttcaaaa atcagtattg cgacaaattc aattaaccac
     1621 taattccatt tattgggcaa ctccattttt acataaaaaa ttaatagaaa tttgtcttca
     1681 aattccagca aaatataaag ttagttcaaa actaacaaaa ccgatattgc aaaaagcatt
     1741 gaagggaatc gtaccaattg aggtttttaa caggggtttc aaaggggatt attcagatgc
     1801 cttatatagt ggatatagag aagcagttcg taaaaacttc cacaatttag aacagtttga
     1861 attggttaaa atgggtatta ttgatgttga gaagttaaaa ttagagatgt cattacccgc
     1921 gggaaatccg agtaaaattg attattttga aaagttatgt tcggtagaac gttggatacg
     1981 gcagatcaaa ttatatatga agaactagtg aggtttacaa ttatgtttaa taaagaatcg
     2041 aaaagtagac tgaaaataat aaagcaagat actggtgcaa ttgtattcga caaaaatcaa
     2101 gggatatact ttcaaacaaa tgatgtaggt gtcaaaattt tagagttact atctaaaaat
     2161 gaaagcgaag aagaaattgt tagcgctata tctgttgcgt attccattga aatcgatgtt
     2221 gcaaaacaag atgttaaaga ttttatacaa tctctaaaaa aaggagggct atagattatg
     2281 gatatgcaac tcaatcaaga gtcatactcc tatgttcagc taaaatacag attactagca
     2341 caaatagctt tactgatttc ttatccgctt acaaagttct cgcctaaaag aattgaactt
     2401 ttgattaata agttaagtaa ctcgaaacta tctgccacag aaaatgaagc aatattagct
     2461 cgtgatgcaa tatgtactgt aagccataag tgtaggaatc aagatggatg cgtaaaaaga
     2521 tcattaggag taataatgtt tttacttctt ttaaataaac gtgcaagttg gtgtactgga
     2581 tttgctatga acccctttag atctcatgca tgggtggaag taaacggaaa tccgattaaa
     2641 gagttagaag aagtatcatc gtatgaaaga gtcgtgaaaa ctctagatga taaaaatgaa
     2701 gagcgtaaac atatgatatc tgaaaatata gaaaaagtag atgatactat gactaacgta
     2761 aaattccgtg atttacttgt tttgatagaa aataaaagaa aatatttttt aatcgtttta
     2821 tgtttgggaa tacttacgtc cattttaacg ttattacaac cagaactttt atctaaagta
     2881 atctctcaaa agggagtaaa tttattcaac aatccaacca tatatatgct tataactatt
     2941 accgtgggtt caacaattat ttccagtttg caatattact ttttacaatt aatgggagaa
     3001 agtgcagtat ttcaatcaag aaaaaattta attattcaat ttttgaaact tcctatttat
     3061 aagtataatg atctatctgc aggagaccta attagtcgct ttagcagtga tacaagtaaa
     3121 ctaagagcag gtatcattca atcaaccgtt gctctgacga gtggattgtt cttgagttta
     3181 ggtgcgatat ttacactatt tttaaaggat acttatcttg caataattac aattatttct
     3241 atagctttat cattcctatt tattttattg atgagtagtt tgattcaaac ggcaagttat
     3301 aaagctcatc agggtttggg gaaaatgaca gcatacctaa ataggctaat cgtagggatt
     3361 agaacaattc ggtcgacaaa tgaaacgaat tcagaattat ctaaaatgtt atctgaggta
     3421 caagaagtaa aaaacttggg aattggagtt gcaagagtgc aatcaataat gacaccaata
     3481 tcaaatttta gcttgcaatt gtgtgggata attattttgg gaattggagg ctaccgtgtt
     3541 tctactgggc aaatgtctat tgcaaatcta acttctttta tgctattaat gtatatcgct
     3601 atttcaccag taggacaaat attttcgtca gtcacaacta tttcagaagc tttgggagcc
     3661 ttaagtagaa ttactgaaat tattgatctt ccaaaagaag aagataatga tatcatttta
     3721 aatctagaat ctaagtcaga cagaagcaaa gcaattgaat ttgtgaatgt aactttttca
     3781 tatgactctt accaatttca agatattcaa tcggatgata attacatatt aaaggacatt
     3841 acttttgaaa taaatagtgg agattacgtc agtattgtcg gtccgtctgg tgcggggaaa
     3901 agtacacttc tttacctcat tgaaagattc tatgatacta ccagtggtgg tataaagata
     3961 tttggacaag attttcgaac aataagtcgt gagactttac gttcgaatat ttcatatgtt
     4021 gaacaaaatt caccattagt agctggtaca atcttagaaa atctaaaaat gggtaatagt
     4081 aatgtaacat atgatgaatg ttgtgacgct ttagaaaaag ttggtttgga gcatttaatt
     4141 caaagaggtg catctgggat tgaaagccca attagtgaag gagggttcaa tttatcagga
     4201 ggagaaagac agagattggc aatggcaaga gcaatacttt ccgatgcaaa gatactcttg
     4261 ctggatgagt taacttcgaa tttggatagt ctgagtgaga agaaaatgaa ggaagcaatc
     4321 aaaagtatga gaggtgagag aaccataata atggttgctc atagattatc tacaatttta
     4381 gattcagatg aaatctttgt tttggaacac ggaagaattg taggaaatgg gactcatatg
     4441 gagttattgg aatctgttcc attatataaa gagctggcca aagaacaatt tttagtatag
     4501 gagtatcgta ttatgacaaa taagattgaa ataagaaatg ttacaaaaac ttataaagat
     4561 ggggatatat taaagaacgt atcctttaca gctgaagagg gggaagtcac ggcctttttg
     4621 ggaccgaatg gtgcaggaaa aagttcgaca ctacgaatac ttttggggct ggatagatca
     4681 tctttaggta ctgctttaat aggaggtaag aaatattgtg acattgaacg tcctctttta
     4741 actgtaggag cttcttttga tggcgtaggg gctcccagtg atcggacagt ttttcaacat
     4801 ttgaaaattg ctgctgctag taatggaata ggtttttcca gaatatcaga ggtattatcc
     4861 attactgata ttgaacataa aagatattca aaaataagca acctttcatt aggagagggt
     4921 cagaggttag gtattgcaac agcgctgttg ggaaatcccc agtacctaat tttagatgaa
     4981 cctacaaatg gtttagatcc tagtggaatt agatggttta gaaattttat tagagaacaa
     5041 gcaagtactg gcaagacagt attgttatct tcacatatac tttcagaagt agaggcggta
     5101 actgataagg ttgtttttat tgacaaagga agtatcatag cttcgggtac acttcataat
     5161 ataatgaacg gatttgataa tttagaagat gttttctttc atttaacagg aggtgactat
     5221 gataagtagt ataaaaagcc ataatatttt atcagagcta tataaaattt tttatagcag
     5281 atcaacccaa atagttttac caattgtttt tattcttcag ccgttattgt cttatatcag
     5341 ttctaaacaa attttaacag ttggattgaa tgcaacacct gaaacaaata gtagtttagc
     5401 agaatcaata cctccaattg agtatattgg ttttgatgca atattattgg gcttgtttgc
     5461 tatgattatt ttaggagcaa ttattggaag tatggaatat aaaaatagtt ctttacgtac
     5521 cagtttgcta ttatgttcaa ataaggcagt attctttgta ataaaatttt ttgttacaag
     5581 tgtatttatt tttgttgtat cgtgtgtttc aatctattta tctattgcaa gtgcacagtt
     5641 tggtttaggg agagagggat tgaaccctct gatactgagt aataatgtgt ggtactttat
     5701 attattgggg tcattgtcgt ggtcgttatt aacggtatta tcctattcaa ttgcttttta
     5761 ttttaaatcc tcacttggat cattattatt cttactacca caagtctata atttaggcag
     5821 ttttctttct gacagaattc agcttgcaaa gtatttacca gtatctttag gtcaagattt
     5881 aattgcaaca tctcctttaa aaatcacaac accaggacgc agtgttttat ttctgagtat
     5941 ttgggtgcta gtaattagta gttttgcata ttacaaattt ttgaaaaaag atgtaggtaa
     6001 tgttatatga attcttttag aagtgagtat ttaaagttta tttataataa atggctatta
     6061 ttgactgtat tagcaactat aattttagtg cctttatttg ttattttttt acatgaaact
     6121 ccaagttata taaccgagga ttatgtttta acgcaaatct tagaaagctt ctatcttgga
     6181 caagctggaa ttattattat tattatacta tttatagggc aagaatttaa cggttcaact
     6241 ttaagaagca gtttattagc taatccaaca cgttggaaat tcttttttat aaaattaata
     6301 gtaatattat caatatctat attagtttgg actctggttg ctttctgtac tatttgcgta
     6361 gtgtatattt tttatggtct attaattccc ttacttattt atacctttac attaagaata
     6421 atattggtat caattggttt aatattaata tgttttagtt tagtgattat aacaaggagt
     6481 atagttgttc caatggggat gtctttgtct tttttgttgg ggttgggtca aatgcttctg
     6541 caattcagcg atgcttttct ctacttccca attatctcca ctatgaattc atttttgatg
     6601 actgagaatc aatcttatat accttataca ataggtattg caattcaatt tttatggggg
     6661 attttgttgt tatctttctc tattttgcta ttttggaaga gaatagtacg ataaaaattt
     6721 tgtattttgt gatattatat aattatgaaa gaaaaaaaag tatatcaaat attagcaatt
     6781 gatgatgatg aaagcattct tcgtttgata aagaattctt tagaacgctc ggagtttgaa
     6841 gttacgacga ggagagaagt aggtaacata gatatttgtt cattcattgg ctttgattta
     6901 attttattag atattatgat gtcgattgat ggtttagaaa tttgtaaatc cattcgagaa
     6961 caaatcgatg taccgataat ttttgtaaca gccaagcaat tggatagtga cttggctagt
     7021 ggagtaaaag ctggtgcgga tgattatata aaaaaaccat ttagtattac agaattagtt
     7081 gctcgtgtta ggatgcatat ccaaagggag gaaagaaatc gtaaaaataa taaagaaata
     7141 tgcacaaaga atttgataat taatgtcagc aatcaagaaa tcttaattga agaagagact
     7201 atatcattga caaagcgaga atttacaatt ttatatactt tagcaagcaa cccgaagaga
     7261 gtatattccg tagaggagct ctatgagaga atatatccgt cggaatcaga tgcacaattt
     7321 cgttctattg ctgagtatat ttatcaaatt cgttcaaaat taaaaccata ttcaattaat
     7381 ccgatcaaga cacagtgggg aggcggatat agttggaacg aaaattagat tttaagactt
     7441 tagtaaaaaa gacgaagtgg acgattgtta aacaattttg tttgaatata attgtagctt
     7501 atatttttcc tatatcaact atttctattg atattcattc agaaactcag tcaatcgctc
     7561 gtgacttgtt aggggtatta tttaatgttt tttcatgggt ttatatttgt atatctttga
     7621 ttattatagt ttctattaat attaaagcct tgttgacaag agtaaagcaa gaaatggaga
     7681 ttgtttatca tagcagtata tggctaacct ctgtaaacga ttcatctaat ttaacaattc
     7741 ttgaattcat agagacaaat agacacattg aatcaatgca acaaagaata aaaaatatga
     7801 ttcaggtaga gaaagaccaa aaggcggata ttctctttaa agtttcagcg atggcacatg
     7861 acttaaaaac acctttgact gtgattaaag gaaactcgga attgttgcaa ttggcacctt
     7921 tatcaggtat tgatgttcaa tgtctcaagg atattgaaag agcaagtaac caattaaata
     7981 gctattttaa tcagttaatc aactactcta aaacttttta ctctgatcag atttcttttc
     8041 atcagtatcg tatcagtaat ttatccaaaa tactggaaca agagtgtaca taccttattg
     8101 gagatagcat tgactacaaa tatagtacta agatagaccg agactgtaat attgaattgg
     8161 atttagattt aattatccgt tcggtggcaa atattgttaa taatgctata gcttatgcag
     8221 atgatgctaa aaagaaaatc agagttacct ttgagttagc agatagcaat attaccttaa
     8281 gtatttggaa taatggttcc aaattttcgg atgatgtttt agaaaatttt ggaaaattat
     8341 tttatcgaga agatactagc agaaattcac aatttgaaca ttttggaata ggtttggcat
     8401 ttgtaaaaca agtaatgagc attcattcag gtgatataca attgcaaaat aaggaaaatg
     8461 gagctatggt taaattaatt attccgatga aaagtagtga ctatgtctag gcttgaatat
     8521 cgtaattttg aatactat
//
LOCUS       DAVHSL010000075         8316 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000075 DAVHSL010000000
VERSION     DAVHSL010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.077"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            266..2763
                     /locus_tag="VVR39_002004"
                     /pseudo
     CDS             266..2763
                     /locus_tag="VVR39_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808684.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase/lanthionine synthetase C family
                     protein"
     gene            2796..4736
                     /locus_tag="VVR39_002005"
     CDS             2796..4736
                     /locus_tag="VVR39_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEU6031407.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            4733..6340
                     /locus_tag="VVR39_002006"
     CDS             4733..6340
                     /locus_tag="VVR39_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031408.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            6355..7095
                     /locus_tag="VVR39_002007"
     CDS             6355..7095
                     /locus_tag="VVR39_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031409.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            7098..>8316
                     /locus_tag="VVR39_002008"
     CDS             7098..>8316
                     /locus_tag="VVR39_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031410.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQMSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIIALIYY
                     SLEDILIDDMNLLG"
BASE COUNT         2872 a         1031 c         1569 g         2844 t
ORIGIN      
        1 gattctctgg agttatggat gtcgttccaa tatgtgcacg ttggaatgtt agtgcttata
       61 tggggagaat ccaaaggatt ctcccttttt atttaaataa gtctgtctag ctatagatat
      121 attaagtttg ataaaatttc ttggagattt tgttatggat tataatttca atttggagca
      181 tcctttcttt ttcactaata atgattatag tacagatact agcataaagt accaagtaag
      241 tctgcctttt aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat
      301 tggaaaattt gttgaaagac aagggtggaa aatacacatt agttcagagt ataacagttc
      361 acatgaattg ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca
      421 tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc
      481 tggtaaattt attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt
      541 agaaagtgcc ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga
      601 agcaccaata tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt
      661 tgctattgat gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt
      721 taaaattcca aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga
      781 taaaaaacag ggagactttc cctttattat agataatgca attagatttt caaacagtgg
      841 tgggatatat aatgctaggc taaaagaaga tgggaaaaaa ataattttaa aagaggctag
      901 accgtataca ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg
      961 caaagcacta aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa
     1021 gatctgggag cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg
     1081 ggttaccaat aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag
     1141 agtttcaaag atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt
     1201 atatcatcaa gatttacatt tagaaaatat cttggttaag gatgaagatg agattagtat
     1261 aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc
     1321 ccctggtttt agagcatggc gagaaacact tcccagtgag atagattggt atggtattag
     1381 acaaatagct cattatttat acatgctact agtaactaca tcggatttga catacaacta
     1441 tgtaagtcaa accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga
     1501 acatatagat tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga
     1561 gaatatttcc aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga
     1621 gcaagatata caagatttta ttataaaatt attgagaggg tttacgctaa cttatggaca
     1681 gtggcgtaaa gaatttcaat caagattctt cccagttcat tattatggtc tgaattttaa
     1741 tcaaggaatt gcgttttcag atttagctat cctttggagt tatcaacaac tagctaagaa
     1801 agtaaaaatt tcaagtttga tgactattat gagattcgaa cacaggttat taatgaggca
     1861 gtaaataatt ttaagaaatc gtccctttct ggtctttttg atggtaaaat tggtacaatc
     1921 tggctcattt atgaatttgg ggagatagat cgggcagttg aactttttac aactcatttt
     1981 atagagatat ttgagaattc acaaaataaa aatttatata gtgggcaggc tggaatttta
     2041 ctggttggac tgtattttct tagtaaaggg gaaattgata ataaactagg agaagaaata
     2101 ctaattaggc ttagagaata tactttaaat tatatagaaa atccagaaac tttttgtaaa
     2161 gttggcgcta gtgatgttca gagtaatgat ccttatgaga attttggtgg attactatat
     2221 ggtcacgcag gggtagcttg gctcttcggt gaagcttata aattaactgg tgaaagtatc
     2281 tataaaaatg gtctagaatt ggctgtagat aaagaattag ttgcttataa agtagatagt
     2341 aataattcat tgcagtacag ccaaggtcat agattactac catatctagc aactggaagt
     2401 gctggcctgc ttttacttat taatagaaat aaagaaatct tgtcaagcaa atacttaaaa
     2461 tatttaactt ctttagagag ggcaactgat gtagtttttt gtgtattacc aggtttattt
     2521 aacggatttt gtggtcttga agttgctaat aatatatata gtgatatcga tgataacttt
     2581 tcaggacaaa agaaattaat tgaacaactt tatagatatt tgtgtgtaat tgaagaagga
     2641 tttgttattg cgggagataa tggtttaaag ataacaacag atattgcttc gggatttgcg
     2701 ggtgttgcaa ttggattggt atcaataatg gataataaat tgacgattct tcctcaaata
     2761 taatatttag ataccattat taaggggtca tacttgtgaa tcagagtaat gaaatatttt
     2821 taaatacaat acaggaaaaa acacactata agaggtctat ctcttcatca tttcaggaat
     2881 taaaaaaatg gaattctttg atatttagga gagggcgata ttggtaccaa tttgataatt
     2941 ggagtatacc caatactggt gtaataaagg aatggtatgt cgaagataat gactggattc
     3001 ctaaggttag ttcttccagt ttagacaatt caaattcact taaaattgtc tttgatgtgg
     3061 aaaaatatac tttgccagat gatagtatct tacaggatgt taggatttca tctgatgaga
     3121 gttatatagt tttggttgta tcctcactgc gtagcactaa tttaattgga ataaaaaaat
     3181 atactatgga agagttattt atcattgaag atatttcagt agaaagttcg ttctatttgg
     3241 gtaaattcgg tgttatgtat actcgctcca aagagtacgg gaggccaagt aagttattct
     3301 ataaatcttt tgatagcttt acagaagagg aactgtttga agaaaacgaa tgctcttttc
     3361 gattaaaaat agtccacatt gatagcaata attgttttgt aaagtcagta gactttcaga
     3421 aaggcaggat ttttctatac agtttcgacc ggacgggttt tgttagacac tcttacacag
     3481 aaacggtagc cccaacacct agagatatcg ctctatttag tacagaaaaa gcacagtact
     3541 ttcttgggct ctcttcaact gaagaaaaga aagatcaact aattctaagg gaaacttctt
     3601 cgggagacag agtttctatt actataccat atcaagatag ggctagaaga gttcactgta
     3661 taggacgtta tatcctttta gactgttcaa acgcagcgaa ttccgtcttt tatcttgcta
     3721 catttaaaaa taatagtttg agggagttga gtgttaataa gataacattt gatgaaaaga
     3781 caacacttta tgaaaattca ttttctgatc gtgttcttct gtttttagag aggagaactt
     3841 tttacgaaaa aatacttagt tttgatttaa tagaaaatac attaaaaact gaatttgaaa
     3901 gacccatcat aaaatcgaat aatactaaat atttttctaa ggtgatttgg actaaaaaag
     3961 acagttatga tgtaagcata ccgatttctt tattttggaa aagtgaagat acggatgagc
     4021 tcccaagaag aaaaaaatgt attctaagtg tctatggggc ttatggtaag aatgataatt
     4081 ctgatttaga tgaaattatg ttatctataa tagatgcagg ttttatttat gctatagttc
     4141 atgtaagagg tggaggctat ttgggtggtg aatggtatcg ctcaggaaag gcgttaaaca
     4201 aatggaattc tatcagagat tttattgagg gagtaaatta tttaagggaa aatgatgtaa
     4261 ttgacagtaa gcgattaggt ttaataactt ctagtgcagg tggaataatt gctggtgcgg
     4321 tgttgaacga ggaaaaaaat ttattgcaaa gcattctctt attttcgcca tttataaatc
     4381 cttatgatac acttcagaat ccaaatgatc ctctttctaa gaccgaaata gcagagtggg
     4441 gagatattag agaccctgaa gtaaaggctt atataaagtc atattcgcct atgcaaaata
     4501 ttgaaaaggc acgagactca aatactgtta tagttaatat tttgggtgag aaagacccat
     4561 atattaataa taacgaagtg atagagtggt caaagaaatt aaattctatt ggagttaaaa
     4621 gtttgttgta tttaaacaaa gcagctggtc atggaggttt tactccatca gatgttctct
     4681 taatgattga tactttaaat tatttctttg aagaagtggg aaggaataac ttatgaatta
     4741 tttaaaattt ataaaaaaga ctaaacttat attaatgggg attttaatat ttctatcttc
     4801 gtttaatggt gtcttgctct caggaattat tgtatatgca ggtagtttaa atcagacttc
     4861 ctcattttct gacgttctaa gatttggtgc tataagtatt ctgggttggt cagcaatcta
     4921 tatatcaaat tactatttag aagtaacgga agcatcaata acgaaagata taaatgtaaa
     4981 aattaaacaa ggatatttta gagaacagta tctttcttct gaaatggtta aagattactc
     5041 atctattatt tcagttttgt caaatgattt gagattaatc gaagaaaact attttagaca
     5101 aatttttgaa ataatttctt caatattgtt gttcatcgtc tctctaagtt ttatgcttta
     5161 tttaaacttc ctagtttcaa taatatttat tgtattatca gcattgccga ttatagtacc
     5221 tgtctttatg aagaagatgt tgtctaattc agctaatgag tactctaaca gcaatgcaga
     5281 gtatactcac ataataaaag aaatttttaa tggttttaag acattaaaat cttattctgt
     5341 tactaaagaa ataattagtt tgtcggataa aaagttggat aaactagaag attctacttt
     5401 taatttgaaa cgatcagagg ttctttcaaa attggttgca gtactaattt caggtttttg
     5461 ctttctagtt cccttggttg taggatgtta ttttgtaatt tatcataaaa gcctttcttt
     5521 tagtgaactg ataggtattt tcttagcaaa cgataaagtt ttagggccga tacaatcaat
     5581 tgcctattca ttaaataaga taaatacaac caaagattta aggaaaccgt ttttaaaata
     5641 cttaagtgga gagaagaatt ttatagacgc tgaacatgat aataacggac tgtatacttc
     5701 atcaatagat gagatacaca tgaaagatgt tgtatattct attacaccag aaaataaatt
     5761 aagtattgac ttctcattta agtcaccatt tagggtatta ttaacaggaa cttctggtag
     5821 tgggaaaaca acgattttaa atttaattaa tggttcttta aagccacaaa aaggttatgt
     5881 aaatttgtta tcacatggga aaaagagttc agattcaata ccaacagttg atcagacacc
     5941 atatattttt gacactacta ttcgtgagaa cgtaacttta tttcaaaatg aatatttttc
     6001 agatgatcag ataattgagg tgttaaaaaa ggtaaatcta tatgaagaat tagaaaagat
     6061 agatatacta aattatcaat gtggtgaaaa tggtagtaat ttgtctggag gtcaaaaaca
     6121 aaaaatagct ttagctagag ctctgattag aaataataaa gtgtacttat ttgacgaaat
     6181 atcagctaat ttagataatg ataattcaaa ttccatacat gatattctgt tcaatttagg
     6241 tatttcattt attgaagttt cacatcatta tgacttaaat gacaagagat acactgatat
     6301 atataaattg gaaaatggaa cacttttcaa aattaagtga ttggaggcaa gaatatggat
     6361 aaagattata tattaaaagt gaaagggctg tatcatcaat ttttactagg aaataataaa
     6421 acgttgcaag tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt tataagtatt
     6481 ctaggaatta gtggttctgg aaagtcaact ttattaaaat gtatttctag tttgcttgaa
     6541 ccaacaagtg gggaagtaat tttaaatgga atcaacccct ataaaatcag aaatgcaaaa
     6601 ttgtcaagta taagacgtaa cgaagtatct tttatatttc aagcatacaa tttaatacct
     6661 tccctgccgg taatagaaaa tatagcactt cctttgcgat tatcacaaaa aaaattaact
     6721 attaaaaatg tagaaaactt actcaaaaga atgaagttta atgctggctt aaacgatttt
     6781 gttggaactc tgtctggtgg agaacaacag aaggttgcta tagctagagc ggttattgct
     6841 gatagtgata taatatttgc tgatgagcca actggggctt tagacagcgt ttctcgtgaa
     6901 gtaatttttg aattattgag agagttagta ggggcgggta agtgtgtaat tatggtaacg
     6961 cacgatatag aattggcctc gaaaactgat cgtgcattaa tattgaaaga tggaaaaatt
     7021 ttcaaagaac ttcatagacc tagcggggaa gagttgtata aaatcttaga ggtacaatca
     7081 actacggagg aatagagatg ctcagattag tttactatca atttttacat aataagaaac
     7141 aatggttagg agtttcacca gtaatttttg tttcgagttt agttatggga ttggctgtta
     7201 atggggtaat taatgttgag aataattcgc aagtatttgt cggacttcca gatcctaaac
     7261 caatttttat gtttccgata gtattcggag gagtaacatt attctttgtg ctctctaaca
     7321 taataaatat gttggttgaa atttttagag atgattacga acttctggag gtgttgggag
     7381 caagtcgcct tcaactatca tttcttgtgg ggggacagat ttttatcatt tcctcgatta
     7441 ttagttttat tgcatatcta tgctctatat ttgttacgtc aaattattat tattttttac
     7501 aatacttttt cggggaaaat atattacctg atatccaatt tcaaatgagt gctgttggat
     7561 gtatcattac agtagtgttg atttcatttt tagcctttct aagtggttgc ttttatacgt
     7621 tcaagaagat tagaaatagg aagagttcta aaataaggca tgttctttca atagtaaaaa
     7681 gaatactgct attggctggt tttagtgtta tctggttgct ttctttgcaa caaattttcc
     7741 aagatagcac aattttagcg aaggcccaga taatattcaa tattgtaatc ttagatattg
     7801 tgattattta tcaattatct ccttttatac agtcatgttt tatcaaacta ctttctataa
     7861 ttatatttag aaataatttt atgttcattg tttcgaagtg gaatttacta tatcgtaagc
     7921 cttatataaa atctatcagt gctgcaatta caggagctat attactaatt tctagttttc
     7981 aaatgatttc tcagaatata ctatctcaat ttcaagatga cagtgattta gagctaaaag
     8041 tggcatttat tgtctatgta ggagcaccaa ttttgatagt acttgcaaat attatttcaa
     8101 ttgcattttt gtcatcgcat caagaaagga ttgagattca gcaatttgaa attttaggaa
     8161 cttctaatta ccagatggtt aagattaaag ttggtgaggc tatatttttg acatttgtta
     8221 cttcattaat tgcattttta cttaacatta aaattattgc tttaatatac tactctttag
     8281 aggatatttt aatagatgat atgaatcttt tggggt
//
LOCUS       DAVHSL010000076         7938 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000076 DAVHSL010000000
VERSION     DAVHSL010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.078"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(209..1177)
                     /locus_tag="VVR39_002009"
     CDS             complement(209..1177)
                     /locus_tag="VVR39_002009"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6031411.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1322..2137)
                     /locus_tag="VVR39_002010"
     CDS             complement(1322..2137)
                     /locus_tag="VVR39_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU6031412.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     STFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2162..2659)
                     /locus_tag="VVR39_002011"
     CDS             complement(2162..2659)
                     /locus_tag="VVR39_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU6031413.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2732..4093)
                     /gene="radA"
                     /locus_tag="VVR39_002012"
     CDS             complement(2732..4093)
                     /gene="radA"
                     /locus_tag="VVR39_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU6031414.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4107..4622)
                     /locus_tag="VVR39_002013"
     CDS             complement(4107..4622)
                     /locus_tag="VVR39_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6031415.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4624..5067)
                     /locus_tag="VVR39_002014"
     CDS             complement(4624..5067)
                     /locus_tag="VVR39_002014"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU6031416.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5127..5220)
                     /gene="ffs"
                     /locus_tag="VVR39_002015"
     ncRNA           complement(5127..5220)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVR39_002015"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5253..5720)
                     /locus_tag="VVR39_002016"
     CDS             complement(5253..5720)
                     /locus_tag="VVR39_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU6031417.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5921..7207)
                     /locus_tag="VVR39_002017"
     CDS             complement(5921..7207)
                     /locus_tag="VVR39_002017"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU6031418.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDSQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7438..7674)
                     /locus_tag="VVR39_002018"
     CDS             complement(7438..7674)
                     /locus_tag="VVR39_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU6031419.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         2532 a         1931 c         1271 g         2204 t
ORIGIN      
        1 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
       61 gtcgctgaaa cttctgatga cgtatagtca tatttcttct ctttttatta tatcacagtt
      121 ttaaatctag ctttactaga ttcaccgcta ctatccattt attcggaaaa aagacgaaaa
      181 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
      241 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
      301 tctgctcaat cttatcaatc aaacgctctt ctggcagata gatggtatcc aaaacaacca
      361 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
      421 tacagcttgc atagacttca acagcaccag cttccgcaag agcatctgcc gcatgacaaa
      481 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
      541 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
      601 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
      661 ccgggctgac aaccacatag tcagaaccaa ccataccacg acgctcaaaa taatctgcaa
      721 tcagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
      781 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
      841 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
      901 aaggcatgac aacattgaca gattctgcac tcgcacgctt caaagcatct accataatca
      961 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaggata aagacgtgtt
     1021 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
     1081 ttgatttccc caactctatc ccaatctcct gcgccacacg ttctgccaat tctttattag
     1141 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
     1201 cgcttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
     1261 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
     1321 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa aaaccataga
     1381 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
     1441 gagagttaaa caagaagtga gttcccaagg ctaaacctag aaaaataagg ccctgtttct
     1501 tgccaacctt ctgtccttta taggctctgt aaagcaagta aacacctact acagctagac
     1561 ctgaaaaagt ccagtgagag gcaattcctg agatgatacg ctctaaaatt cgcgaaatag
     1621 taaagtcaaa gccctctggc aaatccgtac gaatataacc aatatcctca atcatttgga
     1681 atcccaaacc ggaagcaatt ccaagtaaaa acaaagattt taattttcgc acaggaatca
     1741 aagccaaaac aaaaacaagt ggcaataatt tcaagggttc ttctaccaaa ggagccacaa
     1801 tagcactttc aaaggcattt aaaaatgtac tatctgggaa aagaaccccc agtaaatcat
     1861 ggatataagt attagcaaaa ctagacaacc agcctgaaag gaacatccct cccaataaag
     1921 acagaatcaa aaccttcttt ggcaattccc attttttccc aatacggaag agaaaataaa
     1981 gagccggaat catgtaaaag agagctagaa agatagaaac tcccattagt ccatattccg
     2041 cacctgacct cgaaccgtcc gtatagtaga tggtttcata ctgtaaacca atacatagca
     2101 ataaaataaa aataaataaa atactgcttt tcttcataca ctttctttct aaatgaagta
     2161 tttataattc tacgactgtc atacttcctg tatcaacatt gtaaatggca ccagagataa
     2221 tgacatcgtc tggtattagg ggagactcga taagcagttg catatcctcg cgtacactct
     2281 cttctatatc ttggaagggc aagaagtcct ggtctgacac atctacacct aattcctctt
     2341 ttaaatactc ctgaaaaggt tcattttcaa aggtctgagc accacagtct gtatggtgca
     2401 ataccacaat ctctcttgtc cccatttgtt gctgggaaat aactagcgaa cgaatcatgt
     2461 cttcagtcac tcgaccacct gcattccgca agatatgagc atccccaagt gccaagccca
     2521 gagcttgcgc aacgtgcaga cgagagtcca tacaggtcac aatagctact cttgttttgg
     2581 gtttaagtgg cagatttaac tgcccatgta gggcaacata agcctgattg gcttgcataa
     2641 actgttcaaa atacgacacg attccctcct tgaaaatttg atagtcaaat atttctccta
     2701 tcttatcatt tttaagagaa tttgtcacgg attatgcaaa gacctttttc aagacttcct
     2761 gaatcgttgt cacgccaatg acctgaattt ccttaggcag agtgattcct gtcaaggaat
     2821 tcttaggtac ataaatctta gtaaagccca gtttagcagc ttcgttgatg cgttgctcaa
     2881 tacgattcac gcgccgaatc tctcctgtca agcccagttc tccgacaaaa cattcctgag
     2941 gattagttgg cttgtctttg tagctcgaag caatagcaac tgcaacagcc aagtcaatcg
     3001 caggttcatc caatttaaca ccaccagcag atttgagata ggcatcctga ttttgcaaga
     3061 gaagccctgc ccgtttttcc aaaacagcca taatcaagct agcacggtta aaatcaagtc
     3121 ctgtcgtagt acgcttggca tttccaaaca tggtcggtgt taccaaagcc tgaacctccg
     3181 ccaaaatcgg acgcgtccct tccatggtta caacgatgga ggaaccagtc gccccatcca
     3241 aacgctcttc taggaaaact tgactcggat tgagtacctc aaccaaaccg cccgactgca
     3301 tctcaaaaat cccaatctca ttagtggaac caaaacgatt tttgaccgct ctcaaaatac
     3361 gaaaggtgtg gtgacgctcc ccttcaaagt aaagcaccgt atccaccata tgctccaaca
     3421 tacgaggccc agccaaggtt ccttctttgg tcacatgacc tacgataaag atggcaatgt
     3481 tattggtctt ggccaactgc atgagttcag cggtcacttc acgcacctga gaaacagacc
     3541 cctgcacccc tgaaatctca ggagacatga tggtctggat ggaatcaata atgagaaagt
     3601 ctggctggat acgctccact tctgcacgaa cactctgcat attggtctct gcatagagat
     3661 aaaactcact atcaatatca cctaagcgct ctgcacgtag tttaatctgc tgggcagact
     3721 cctccccact gacatagaga actgtcccca cttgggacaa ctgggttgag acttgtagga
     3781 gaagggttga tttcccaatc ccaggatccc caccgatgag gacgagactt cctggtacca
     3841 ctccgcctcc aagcacacgg ttgaattcct ccatctccgt cttggttcga ttgacattga
     3901 tggaagtcac ctcagctagt ttcatgggct tggttttctc acctgtcaag gacacacgcg
     3961 cattcttgac ctcggcaacc tcaacctctt ccacaaaaga agaccaagac ccacagttgg
     4021 ggcaacgtcc cagatattta ggggaattat acccacaatt ttgacataca aatgtcgctt
     4081 ttttctttgc gatgacaaac ctctttctat atctctaact cacactcaat cacttggcaa
     4141 aaatcaatct tctcatttgg cacaaactgg cgcatgagca ttcgatgagc aacaactacc
     4201 acagtctgat gttctcgata cttagacata cattctagaa accgagactt catttccgta
     4261 gctgtctcat attgaatagg actattagga agcaactccc ccttgttttc taaaaacagt
     4321 cttctagctg tttcaaagtt ttctattcct gttttataga cctgccattc atgtaataaa
     4381 ggctctactc ttaaaggaag acccgtagca cagaccacat acgaagccgt ttctaaagct
     4441 cttgtgactg cagaagatac gattatttca gctgacgaga gtaaaggatt tttgctcaat
     4501 ttctggactt gctgccgtcc catctcagac aagggtgcca aatctatccc aaatcctata
     4561 taagaacgct cctctaactc acggtaatct ggctccccat gacgtacaaa gataatcttc
     4621 attctagtgc cctgtcgatc caaatccacc agttcgaacg ccatcagccg catctccatc
     4681 tgcaattaag aaagtagcaa aaacagcctg gacaatacgc tccccaactt caagaacaac
     4741 ctcttggtct gtgatattct tcatctgcgc aaaaatatgc ccttcatttc caggatttcc
     4801 ataataatct ccatcaatga ccccaactga gttaattaaa accaagccct tcttacgagg
     4861 atttgaagaa cgatcataga ggtagagaac ctcagtcggc tgcatataag ccttaacccc
     4921 tgtcggaacc aagacaatct ctcctggcgc aacaactgta cgcacagcaa cctttaagtc
     4981 gtaaccagcc gcatgcgctg tctcacgctt gggcaataaa ttttcatctg taaaactcga
     5041 aaccaattca aaaccacgaa ttttcataat tttctctttt ctattatcat ttattctaga
     5101 ttattctatc ttatttattc ggaaaaagca cgaaaaaaga gcacacaatt caaatcgctt
     5161 agggctgctg gattcctccc ctgacccgct tcacgcagaa ctgttgctcc actatttatt
     5221 atatcacatt cctattcatt ttaaaagcaa aattattttt tccgtctatt tctaaaaaaa
     5281 tcctgcatga tagctgcgca ttcatcttcc aaaattccta tttcaacctc cacacgatga
     5341 ttgagacgct catctgtcaa gatatcgtac aaactcccag cagcgccaaa tttctggttt
     5401 ttagccccat agaccacatt tggaatgcgg gcaagcccaa tcgccccact acacatgaca
     5461 caaggttcaa tggtcacaaa aagtgtgcaa tccagcaagc gccagctctc ctcactcaag
     5521 ttcgcatcct ctatagccat aatttccgca tgcataaccg ctcgctgtaa ttcctcacgc
     5581 gcattatgcc cacgaccaat gatttcccca tctttgacaa tcacacaacc aattggaatt
     5641 tcatcgtgtt caagagcaat ctcagcctct ctcaaagcct ccctcataaa gacttctttt
     5701 tcttcaagcg tataatacat ctcttttctc ttttcctact tatcgatttt attattatat
     5761 catgaatccc aacacaaaaa aagccaccga atgcggtgac tctataggga gattattatg
     5821 aaaaagaaaa gtttaggata tttgttacaa caagttagga ggtcttcttg taactgtcta
     5881 tagtataccc gacctatctt aaacaaatct taaaaatctc ttaggaccaa acgctttcta
     5941 aaatatttgt ttgttcacga ccaggaccta ctgagaaagt agaaatacga acgccaacca
     6001 attcactcac acgacgaaca tagttacgcg cattctcagg aagatcttcc aaattgcgaa
     6061 ctccggtaat atcttctgac caacctggca actcttcata gataggcttg caacgtttca
     6121 attgctcaag actagctgga tagtagtcaa tacgttgact gtcaagatca taggccacac
     6181 agattttcac agtatccaaa ccgctcaaaa catcaataga gttcaaagaa aggttagtaa
     6241 taccagaaac acgacggcta tgacgcatca caactgagtc aaaccaacct acacgacgtg
     6301 gacgaccagt tgttgtacca tattcatgac ccacttcacg gatacgttct cccacttcat
     6361 caaacaactc agttgggaaa ggaccatctc ctacacgact cgtataagct ttacatacac
     6421 ctacaacctt gtcaatcttg cttggaccaa caccagaacc aattgtcaca ccaccagcta
     6481 cagggtttga tgacgtaaca aatggataag taccttggtc gatatctagc ataacacctt
     6541 gtgcaccttc aaaaagcaca cgtttgccat tatcaagcgc atcattcaag ataacagatg
     6601 tatctatcac gtatttcttg atttgttgac catattcgta atattcttca aaaatatcat
     6661 cgaaaacaat cgctttactg tcatacaatt tttcaaaaag acgattcttt tcagcaaggt
     6721 tacgttctaa acgctcacgg aaaatatctt tatctaaaag atctgcaata cgaattccaa
     6781 cacgagcagc cttgtccata taagctggac caattccctt aattgtcgta ccaatcttat
     6841 tgtcgccctt agcttcttct tgcaagcgat ccaactcgat atgataaggc aaaataacat
     6901 gcgcacgatc agaaatacgc aagttatcag ttgttacacc ttcctcatga agatagctca
     6961 actcttttac aagagattta ggatttacaa ccataccatt cccaatgaca gatatttttt
     7021 cagggaagaa aatcccagat ggaatcaagt gcaacttaaa tttcttaccg tcaatcacaa
     7081 tcgtgtgacc agcattatca ccaccttggt aacgtgcaat cacttctgca ttcgctgaaa
     7141 ggaagtctgt aatcttccct ttaccttcat caccccattg ggtacctaca acaacaactg
     7201 aagtcataat tttgtctgag ccctcaggct cttcctttct cacatacatg gcaggactct
     7261 cacctgcaat tatatcttac aatttattat aataaaaaat cgccttttta tcaagaagaa
     7321 acaatagaaa gatttgctat ttccaactat taaaaaatga tttagaaaaa ttactagcta
     7381 tttactatta tctttccata aaagagtaaa ttagttcgga aatttactaa aattacctca
     7441 acaagaaata aacccccgat tcattaccaa tttttcaaga tacaaacgat aagcaacacg
     7501 ataatggtaa acgataaaat ccctacgaca accaatgcca tatctcacta aataataaat
     7561 taaaaattta aaatgaacat gttcccagtc aaaattatca ccaaatgtag gaccatactc
     7621 ttcttcaata ctatcataga aattagccat ctgctcataa attttttgta acataatcaa
     7681 atactccttt tcttttttat aaacttattc taacaaaaaa ttttacacat tcactatcaa
     7741 ttcctgaatt gttaaaatac cagcctcaac aagataaaaa taggaaaagt tgacaaaata
     7801 gaaacaaatt tgctacctaa atttcaaaca attaaagttc taaaaagacc gccttaaaac
     7861 ttttgggtaa atcctattaa aactataata tttttatata ggtattatgg ttctgatttt
     7921 ctagtataaa aaaattca
//
LOCUS       DAVHSL010000077         7483 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000077 DAVHSL010000000
VERSION     DAVHSL010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.079"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(201..1592)
                     /gene="argH"
                     /locus_tag="VVR39_002019"
     CDS             complement(201..1592)
                     /gene="argH"
                     /locus_tag="VVR39_002019"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6031420.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAHHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TIGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(1621..2818)
                     /locus_tag="VVR39_002020"
                     /pseudo
     CDS             complement(1621..2818)
                     /locus_tag="VVR39_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(2835..3641)
                     /locus_tag="VVR39_002021"
     CDS             complement(2835..3641)
                     /locus_tag="VVR39_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6031421.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3848..4489)
                     /locus_tag="VVR39_002022"
     CDS             complement(3848..4489)
                     /locus_tag="VVR39_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031422.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4486..6594)
                     /locus_tag="VVR39_002023"
     CDS             complement(4486..6594)
                     /locus_tag="VVR39_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6031423.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6646..6933)
                     /locus_tag="VVR39_002024"
     CDS             complement(6646..6933)
                     /locus_tag="VVR39_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6031424.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            7359..>7483
                     /locus_tag="VVR39_002025"
     CDS             7359..>7483
                     /locus_tag="VVR39_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6031425.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQIC"
BASE COUNT         2277 a         1699 c         1221 g         2286 t
ORIGIN      
        1 ctgccaagcc acatagtgtg tttactacta tgtgtccatg tcaccatgaa tcgccgaacg
       61 atttaacgag aaagtatgac ttttacgttt atcccaactc aattatgaca tttttttcaa
      121 aagtcaatat atctcacttt ttcaacgaca agaaagaggc tgccaatcga ccaacctctt
      181 attctgaacc catcactcca tcacttttta gcttcattcg ctttcttagc gactgcaatc
      241 tggtattcga cttggtcaaa ccctgtgcct cccaaggaat ttcgtctttg aacagcagtt
      301 ttaggttgca agtagacata gatatcctcg gtaatgagag aatgataggt ttgtaattcc
      361 tccaaagtcc aatcttgaag atttttagca gacttgatag agtctagcac taatcttccc
      421 acaacctcat gagcttctct aaatggcaag cctttccctg ccaaataatc tgccaactca
      481 gttgcatttg aaaagtcctt ctctgttgat tcttgcattt tttccttgtt tacctgcaaa
      541 ctagataaca tacctgccaa cacatcgagg gaatttaaaa tcgtttcgac cgtatcaaac
      601 attccttcct tatcttcttg caaatcctta ttataagcta aaggcaagga cttcatgact
      661 gtcaacagtc caaacaaatg cccataaact ctgccagtct ttcctcgaat caactcagcc
      721 atatctggat ttttcttttg gggcataata gaggaaccta ttgtaaacgt atctgacaag
      781 gtaatgaatt ggtactcaaa actacaccaa ttaatcattt cttcgcaaaa acgactcata
      841 tgcatcatga gtatgctggc atttgataga aattctaaga taaaatcgcg gtcactaaca
      901 gcatccaaag aatttgtata aggttgctta aactccagca aatcgctaga caattggcga
      961 tcaatgggga aagtcgttcc tgccaaagct gccgcaccta aagggcatag gtctgtatgc
     1021 ttctggttaa attcaaaacg ttcactgtct ctttgaaaca tattgtagta agccatcagg
     1081 tggtgggcaa aactaatagg ctgggcatgt tgcagatggg tatagcccgg catgatcgtc
     1141 gccacatgat tttccgccaa gtctaataaa acacccttaa gatgagccag tttatctagg
     1201 acatagccta gttgttcctt gagatacaag tgcatatctg tcgcaacttg gtcatttcga
     1261 gaacgagccg tatgtaactt ccctgcaagg ggaccaattt tttctgtcag caacacttcc
     1321 atattcatat gaatatcttc gtttgcgata tcaaagtcaa gttgacctgc ctctagctct
     1381 tctaaaagct ctttcaagcc tacttgaatc ttttctgact cctccaaact caaaatgccc
     1441 gtctgaccca acatctgaac gtgggctaaa gaaccaatca catcaaattt agctaatttc
     1501 tggtcaaaag atatactcgc accaaagcgc tctacccagt cttcgacagt accttcaaag
     1561 cgaccacccc ataattttgt attcttagcc atatcacatc cacctctcta tccaatcgtc
     1621 ctatttggcg cttttttgaa cctcagaatg aaccttggtt ggaagtcccc ataactcaat
     1681 aaagccaaca gccgcatctt ggtcaaaggt atctgcacta gtatacgtcg ccaaattttc
     1741 atcgtaaaga gaatttggtg atttccgagc cacgacctga gcactccccc ttatacagtt
     1801 tgacttttgc agtcccattg acaacttttt gagtctcttt aatataagca atcaaggctt
     1861 gtgtagccga actaaaccac aaagcattat aaatgagatt tgataattca ttttctatga
     1921 ttggtttaaa atgagccact tctctcacaa gcgtcaagtc ctcaatttcc ttatgagctg
     1981 tcagcagggt cactgcacct ggacactcat agatttctct tgatttaatc ccaaccaagc
     2041 gattttccac gtggtcaatc cgtccaaccc catgttttcc agctatttca ttgagttttt
     2101 gaatcaaatc tgccaatttt aacacttctc cattgaggga aactggaaca ccttcactaa
     2161 actcaatctc aatgtattct ggcatatctg gagcttgctc tggagaagtt gtgatgccaa
     2221 aggcttcttc tggagcctga ttccatggat tttccaaaat accacactca ttggcacgtc
     2281 cccaaagatt ttggtcgaca gagtagggat tgtcaaggtc agcaggaaca ggcaccccat
     2341 ttttcttggc ataataaatt tcttcctccc gagaccattt ccattcacga actggagcaa
     2401 tcacttttaa attgggatcc aaggctgcaa tcgatacttc aaaacgtact tggtcattcc
     2461 ccttaccggt acaaccatga gcaattgtag tcgctcctat ctgatgcgct atttcaacca
     2521 attttttaga aataagaggg cggctcaagg cagataccaa ggggtacttt tgttcataat
     2581 aggcatgtga ctgaagagcc actagcacat aatctgtagc aaattcgtcc ttgacatcaa
     2641 tgacataaga ttcgactgcc ccaaccttga gagccttatc atggatgaag tctaagtctt
     2701 tcccttcacc cacatccata caaactgaaa caacatcata gtctttcttt aaccaggtaa
     2761 tagcaactga tgtgtccaaa ccgccagaat aggccaaaat tactttttct ttactcatgt
     2821 tcttttcctt ctttctattt ttcaatggat gctttaaagg catcctcaat gagtttgtct
     2881 aattccccag actccttcaa cttttgaatg gttttatcga ctgcctcttt caattccttg
     2941 ctatcttttt tcatggctac cgcgtaggaa tcatcttgct ctttttcaaa attgaggtct
     3001 gcgattgcta aatcaggatt attttccaca aatcccttgg aaacaggttc ttcaaagata
     3061 acggcatcca cttgtcctga ttttaaatct gtgattaaat tcccattttt aggcagagat
     3121 acgagggaag aattttgtag caaatctttc gccatcgtct cttgaatcga acctttctgc
     3181 gctccaacct ttttctgcgc caagtcgttt acagactgat aagtagtcaa gtcagatttt
     3241 ttgacaatga gtttattttt tgcagtatag tagggaatgg aaaagtcaaa caccttgctc
     3301 cgttcatctg tcttagaaac acctgatatg gcaaggtcgg cttttcctga ttgaacacta
     3361 gccagtacat tatcaaaact catgggagat agttccaatt cgacacctag ttctgttgcg
     3421 atagccttgg ctaattcgat atctgaaccc acaatctgat ttttcccatc aaccactttt
     3481 tggtattcaa atggagcaaa atctggattg agggctacaa ccaattttcc tttggacttg
     3541 atggcttcaa ttccagccga ttgattgttg ctacaagcaa atagtagggg gagcatcact
     3601 aaaccaaaca tcgtcatcaa caccttcttc atcttattca taacaaagtc tcctttatgt
     3661 ttattctttt tggttgtata aataatactc ccatactcat cctttgtcaa gcctaaattg
     3721 aaaaaatttt caatttgaaa caaaaaaaac ctagaaatac tacataaaat gtcattccta
     3781 ggcgtattta tgctattttt ctctggaaaa catgagtatt cagccagtca aaaggagctg
     3841 aatgaactca ttttccctcg cccaattcaa tgacacgatg acattgttgg gctacataag
     3901 catcgtgggt cacaataatg actgttttcc cttctcgatt catctctaag agaaacttca
     3961 agaccaaatc tctattttca ggatccagcg aacctgtagg ttcatcggct aaaatcagct
     4021 ggctgggttt taagatggct ctagcaactg caattcgttg ttgttcgccc ccagacaact
     4081 cggagaccct ttgatgcaaa gtagctgaca aacctactct ctctaaaatc tcttccacct
     4141 ttttgagctt gtctttctta ggcaatttca catatttcag cgccagcatg agattgtact
     4201 cgaccgtttc atcatcaatc agggcaaaat tttgaaacag ataagagata tgttcacgga
     4261 ttattgtttg cgacttagca gaattaaccg ctagatttgt ctgaccaaaa atctcatacc
     4321 gtccgctata atcaccatct atcaaaccca ataaatttaa caaggtcgac ttcccactac
     4381 cactcttacc aacaatagct accaaatccc cctgatcaat cctgagagat aagttatcca
     4441 aaatcacttt tcccccaatg gttttggtaa tatttttcaa ctcaatcata agatgccccc
     4501 tttcaataac tctactagac ttcttttctc catcctagaa gctaagccta gcacaaatag
     4561 tatatccaga catgtaaaac ctgcaaacag tagaagtggt aagaacgcat gggcaaagaa
     4621 aatcaagact agaagaggga aactatagcc cagcaagagc agaacgagga gaggacggta
     4681 gcgatcgacc agtttccacc ccataaactt cttggtaatg atatccctgc gcttcaataa
     4741 gaaagttgtt actagtaaga agtaggaaat catcatgcta aggagaccaa acaaagcaaa
     4801 gagtaggtta aaattccgaa cagcatctct ataagaatcc actttctctt gttgaatggc
     4861 ttgaatagat gaaaatttta aataatttcc atctgacaat ttctcaacta actctgtaat
     4921 ctctttttga tgttgaaccg tattttcaat tttaatcgga ttatttaagc cagttgttga
     4981 cagggaggct ttctcatccc acatcatatc agaatcattg accaagctaa taattggatt
     5041 ggagagattt tcctttcgct tatcactata tgggaaaaat gaccaatctc cttcataata
     5101 ggcaatctcg acatccatct cctctatcgt tcgtttttgc tgctcttcat acttcatcga
     5161 atgaaaggca attaacttcc ccaagagctg atttttatct tcttcacctt tcgtacttgc
     5221 tggcatcaaa ataacttttt taataccggt atctggtagc ttgaatccct tgctctttag
     5281 aaaattgcga ttggcatagt aaacatccac cgtatctgtt aactgatatt gctgaatctg
     5341 ttctgattgg acaaaatttt ttacaggaag actgctactc tgcacatagc ccgcctgcgt
     5401 tttttctacc aaatcctgat aaaatcgata gaaataatct gtagatttcc ctgaccctgc
     5461 tagctcttct tgccacagat tatcattgag tttgaaggtt tctaaggtca ggtaattacc
     5521 ttgacttacc cactgttgct gataagcaag ttctttgttt tcttgttcta aacttctgcc
     5581 caccccaatc agtaaggccg tcagtaaaat agttgtccct attttcatca cataattgaa
     5641 gataagacca aatttgaaag atgaaaaacc tttcagcaga gagctgattg tcattttttg
     5701 gattaagagg taagtcaacc aactgataaa gagataaagc tgcaacagca aaaaatgaga
     5761 caaccacagc ataggaaaca aatcttttgg cttataatca agcaagaaaa acacgcctag
     5821 attgatcaca agagccccac ctaggaggag gtaaaggttg ccttttacaa catcagctaa
     5881 aacagcccta tcttgaaaac caagtaattt ttgtacccca actcttttca tctccatcat
     5941 cggttgatac actgtcacta acacaagaag caaaatagcc aagacaaaaa caatggcaga
     6001 taaaagcaaa tctcgattta tgacttccac tgcacttttg taggtcggct ctagcaaggt
     6061 agcctggtct atcttgaaaa aatcgctcca tttctgtaca atcctatcct tgtccatctc
     6121 ttgtgtagaa gttatcgtat agcgaccatt taaactacga gatgtatcct tgatataggt
     6181 ttgaaaagtc ataagctgaa taggtttggc ttttagaaag gtcggaatcg taccaagttt
     6241 attggaaatt tctttattac tatagactcc ttcaccatct gtggtaaaat caagagaaga
     6301 aatcccaaac tcttggtagg ggaaggtatc tttatcaaaa acaccagact tgaccacctc
     6361 atcaccactg tctgttttga tgatggagac tttatactcc tttgatacat cctcaaaaaa
     6421 tcgaagaaca gacgctgcag gttcgttaat atctttcaaa tacaaatcca aagaatctac
     6481 agtctttccc atttcttgaa tccgaaccac ttctcgtgta tagtttacat taaaaacaaa
     6541 aaaagtggta cacagaagca ggagtaacat acagaaatta ctgatttttt tcataaaagt
     6601 gcctccacta cagttttccc tctccaaata ggagagggaa gaattttact caaatccata
     6661 gaaatattcc attcctgttg gcggaatctt ggtgagggaa gctctagccc atgcctcagg
     6721 ttttgcataa tccttagagg ttctaccccc atgtctaaca gttgctgtat gatatcgagt
     6781 agaatgtaag taatcagaat atccaaaagt tcctgtccaa cctactccat agttccattg
     6841 accaccctca acccatactg ctaaagcatt tgtagtagca agtataccac ataccattaa
     6901 agatgcaaca ccaattttaa ctaattttct catgatttat ttctcctatt atcgagagct
     6961 gttccgtaaa aacagctata gtaatttatc aacaagtatc gtagtccatt ggactcacct
     7021 tccttctatc tcatttcatt tttaaacaac gaacttactc ttaactagaa gaatagttct
     7081 cttctgtatc aggtctttga acaaccagag tagtattaat cacactctaa ctattactca
     7141 agaatcagcc caataaacaa catggatagc gctttcaaat ttttaaactc ttatcccatc
     7201 cttttatcta tataataagt gaaaatataa taactgtcaa gtaatcgaag taaattttat
     7261 aaaaaaaatt acaagccaaa tttgtaaagt ttacactaag ccgctagggc aatcgtctat
     7321 cagaatgtcc gtttatttgt caataatccg agaaaatctt gcaacgctta gaagtctata
     7381 aaaactatca acgtttatat gacttgcgaa tagcaatcct gctcaacctt tccacactct
     7441 atctatacaa tcaagataaa aacatgtgta agcaaatctg cta
//
LOCUS       DAVHSL010000078         7269 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000078 DAVHSL010000000
VERSION     DAVHSL010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.080"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..496
                     /locus_tag="VVR39_002026"
                     /pseudo
     CDS             1..496
                     /locus_tag="VVR39_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            557..1519
                     /locus_tag="VVR39_002027"
     CDS             557..1519
                     /locus_tag="VVR39_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6031426.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFMKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1696..2703
                     /gene="gap"
                     /locus_tag="VVR39_002028"
     CDS             1696..2703
                     /gene="gap"
                     /locus_tag="VVR39_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU6031427.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2771..3607)
                     /locus_tag="VVR39_002029"
     CDS             complement(2771..3607)
                     /locus_tag="VVR39_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6031428.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3733..5928
                     /locus_tag="VVR39_002030"
     CDS             3733..5928
                     /locus_tag="VVR39_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6031429.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5981..6133
                     /gene="rpmG"
                     /locus_tag="VVR39_002031"
     CDS             5981..6133
                     /gene="rpmG"
                     /locus_tag="VVR39_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6031430.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6143..6319
                     /gene="secE"
                     /locus_tag="VVR39_002032"
     CDS             6143..6319
                     /gene="secE"
                     /locus_tag="VVR39_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU6031431.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6374..6910
                     /gene="nusG"
                     /locus_tag="VVR39_002033"
     CDS             6374..6910
                     /gene="nusG"
                     /locus_tag="VVR39_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU6031432.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            7032..>7269
                     /locus_tag="VVR39_002034"
     CDS             7032..>7269
                     /locus_tag="VVR39_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6031433.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKR"
BASE COUNT         2274 a         1252 c         1579 g         2164 t
ORIGIN      
        1 cttatttctt aaaaatttta atagtttaaa gcacctagca cctgtttaga ttgatgaaac
       61 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaataag
      121 aggtaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg
      181 tgagttaatc gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagcttg
      241 gtttcagaag tttctcttac caacattaac cacaccatcg gttattatta tggataatgc
      301 aagattccat agaatgggta agttagaact tttatgcgag gagtttgggc ataaactttt
      361 acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa
      421 aaagcacctc aaaagggtat taccaagttg caataccttt tatgaggctc ttttgtcttg
      481 ttcttgtttc aattgactat agttcacgga tacagttggg aaagaagcca ttaaacattt
      541 ggagagtcct tttgggatga acatgtcaaa tattactata gatgggcaag aaatggatct
      601 gagtcaaacg atgccttctt atgctcaagt agtgagtctt tatgaggata caagcatctc
      661 tgttagtagt aatgagacgg acaaagtgtt ggctggatcc ctctatactg atacaaatga
      721 acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa
      781 tttgacagct aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc
      841 cgaagctagt aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga
      901 tgacatggag gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga
      961 ggctggattt atgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac
     1021 aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag
     1081 agttcttgat attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc
     1141 atcacaagct attgtggtag cagcggttat gattggtatt attatttaca tcaatatcat
     1201 gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt tatcagaatc gtgatgtcaa
     1261 aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt
     1321 ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat
     1381 cactaaggtt tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt
     1441 acttggttat gtctcagcct acttcccggc acgtaagatt agtaaaatgg atcctgtaga
     1501 atcgttacgc tatgaatagt aagggattcc ttgatttaca gtcttaaaaa gaaactaaca
     1561 tagaaaaaca atggccatac ttgcaattca actcaaatag ttgtataata ggtttgttga
     1621 aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata
     1681 aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt
     1741 cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt
     1801 acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac
     1861 ggtactgttg aagttaaaga aggtggattt gaagttaacg gtaaattcat caaagtttct
     1921 gctgaacgtg atccagaaca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa
     1981 gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa
     2041 aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caacactaac
     2101 cacaacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc
     2161 ttggctccaa tggctaaagc tcttcaagac aactttggtg ttgttgaagg attgatgact
     2221 actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac
     2281 cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgcaaaa
     2341 gctatcggtc ttgtaattcc agaattgaat ggtaaacttg acggatctgc acaacgcgtt
     2401 ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt
     2461 gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat
     2521 ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa
     2581 actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac
     2641 gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa gattgctaaa
     2701 taattcttga gttgatagaa agcaaggctt tgtggtcttg cttttttata tggaaaaatg
     2761 gatgacacga tcatccattc ttttttaatt ctttttcaaa tgtatttgaa agggtagtga
     2821 aagttagcct ctctaaagta agtgggtggg taaaggaaag tcggaaggca tgaagcataa
     2881 gccggcttgt ctttgattta ctattataga gagggtctcc caggatagga agattatgat
     2941 gcaaaaggtg cacacgaatc tgatgggttc gccctgtctt tagcttgcaa tgagccaagg
     3001 aagtcttgtt tgagaattgc tttaatctgc ttacatgcgt ttcagcatat tgcccatttt
     3061 ttgcatcaac tattcttttt ctacgatcat ggcgatcacg tccaattttg tctctgaaaa
     3121 caagttcttt tctgttgata tttccatcaa ctagagccca atattctcta gaaatctctt
     3181 ttttctccaa taagcgattg agaatgggca ggataaaagg atttttggca aagagaacta
     3241 agccactggt ttccatgtcc agacgatgaa cgacatagca ggtttggcca acataggtac
     3301 tgacatggtt aagaagggca atttcgtttg gttgattacc atgcgttttc atcccctctg
     3361 gtttgtttac aataatcaag tgttgatctt gataaacttc ctgcactaag tctgggttgc
     3421 cccaagggat cgtcttttgg gaataatctt cctcgtcaaa agtcaactgg caaacatctc
     3481 caggatttac gatttcgttc cagtggactt cttcttgatt tatcaaaata tgtttcttga
     3541 ttctcaaaaa atgacggatt tttctaggga tgaggagttg ttcctcaagt aattgcttta
     3601 ccgtcatttg aggtagagag gcgggtaatg taaatgtgaa ttgcatacag atattgtaac
     3661 aaaaaaagcc ctatttggat aggaaatagc taaattcttg tcttcctatg atgaagatga
     3721 taaaataaac gcatgaaatt agataaatta tttgagaaat ttctttctct ttttaaaaaa
     3781 gaaacaagtg aactagagga ctctgattct actatcttac gtcgctctcg tagtgatcga
     3841 aaaaaattag cccaagtagg tccgattcga aaattctggc gtcgttatca tctaacaaag
     3901 attatcctta tactaggttt gagtgcaggc ttgctagttg gaatctattt gtttgctgta
     3961 gccaagtcga ccaatgtcaa tgatttgcaa aatgccttga aaactcggac tcttattttt
     4021 gaccgtgaag aaaaagaggc tggtgccttg tctggtcaaa agggaaccta tgttgagctg
     4081 actgacatca gtaaaaactt gcagaatgct gttattgcga cagaagaccg ttctttctat
     4141 aaaaatgacg ggattaacta tggccgtttc ttcttggcta ttgtcactgc tggacgttca
     4201 ggtggtggct ctaccattac ccaacagctg gctaaaaacg cctatttatc gcaggatcaa
     4261 actgttgaga gaaaagcgaa agaatttttc cttgccttag aattaagcaa aaaatatagt
     4321 aaggagcaaa ttctaaccat gtaccttaac aacgcttatt ttggaaatgg tgtgtggggt
     4381 gtagaagatg cgagtaagaa atactttgga gtttctgcat cagaagtgag tctggatcaa
     4441 gctgcgactc tggcagggat gctcaagggg ccggaactgt ataatccctt gaattccgta
     4501 gaagattcta ctaatcggcg cgatactgtc ttgaagaata tggttgcagc aggatatatt
     4561 gataaaaacc aagaaaccga agctgctgaa gttgatatga cttcgcaatt gcacgataag
     4621 tatgaaggaa aaatctcaga ttaccgttac ccctcttatt ttgatgcggt ggttaatgaa
     4681 gctgtttcca agtataatct aacagaggaa gagattgtca ataatggcta ccgcatttac
     4741 acagagctgg accaaaacta ccaagcaaat atgcagattg tttatgaaaa cacatcgcta
     4801 tttccgaggg cagaggatgg aacgtttgct caatcaggaa gtgtagctct cgaaccgaaa
     4861 acagggggag ttcgtggagt tgtcggtcaa gttgctgaca atgataaaac tggattccgg
     4921 aatttcaact atgcaaccca atcaaagcgt agtcctggtt ctacaattaa gcctttagtt
     4981 gtttatacgc cagcagttga agcaggctgg gctttgaata agcagttgga taaccatacc
     5041 atgcagtatg acagctataa ggttgataac tatgcaggga tcaaaacgag tcgagaagtt
     5101 cctatgtatc aagccttggc agaatcgctt aatctacctg ctgttgccac tgttaatgat
     5161 ttgggtgtcg acaaggcttt tgaggcaggc gaaaaattcg gactcaacat ggaaaaggtc
     5221 gaccgtgttc ttggtgtcgc cttgggaagc ggtgttgaaa ccaaccctct tcaaatggct
     5281 caagcatacg ccgcctttgc aaatgaaggt ttaatgcctg aagctcattt tattagtaga
     5341 attgaaaatg ctagtggaca agttattgcg agtcataaaa attcacaaaa acgggtgatt
     5401 gataagtctg tagctgacaa gatgaccagt atgatgttgg ggactttcac caacggtacc
     5461 ggtattagtt catcgcctgc agactatgtc atggcaggga aaactggaac aactgaagca
     5521 gttttcaatc cggagtacac aagtgaccag tgggtaattg gttatactcc ggatgtagtg
     5581 attagccact ggcttggctt tccgaccact gatgaaaacc actatctagc tggctctact
     5641 tcaaacggtg cagctcatgt ctttagaaac attgccaata ccattttacc ttatacgcca
     5701 ggaagtacct ttacggttga aaatgcttat aagcaaaatg gaattgcacc agccaataca
     5761 aaaagacaag tacaaaccaa tgataatagc cagacagatg ataatttgtc tgatattcga
     5821 gggcgtgcgc aaagtctagt agatgaggct agccgggcta tctcagatgc gaagattaag
     5881 gaaaaggctc aaacaatatg ggattcgata gtcaatctat ttcgctaaga tgcttgtcaa
     5941 agcctagctt tcttgttata atggataaga tggaggcgtt atggcactaa aaaaagcaag
     6001 cctagcttgt gcggtttgtg gttcgagaaa ctattcaatc aagatcagcg gaaaccccaa
     6061 gcctacacga ctagaagtaa ataaattttg taagcattgt ggcaagtaca ctacacacag
     6121 agaaacgaga taggagagag cgatgcgttt tattggagat atttttagac ttcttaaaga
     6181 cacaacatgg ccaactcgca aggaaagctg gagagatttt cgttctatca tggaatacac
     6241 agctttcttt gtagtaatta tttacatttt tgaccagttg attgtttcag gtttgattcg
     6301 atttattaac attttttaga agattagtgg agttaattac actagaaatc ttctatttat
     6361 gaaaggaaat atcatggata gttttgataa aggatggttt gttttacaaa cttattctgg
     6421 ttatgaaaat aaggtgaaag aaaatctatt acaacgtgca caaacctaca atatgttgga
     6481 taatattcta cgcgttgaaa ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag
     6541 aaaagaagta gaagaaaatc gctttccagg ttatgttctt gtagaaatgg tcatgacaga
     6601 tgaagcttgg tttgttgttc gaaacacacc aaatgttaca ggatttgtcg gatcacacgg
     6661 gaacagatca aaaccaactc cattattgga acaagaaatt cgtgacattt tggtatctat
     6721 gggacaaact gttcaagaat ttgatttcga tgttgagatt ggtcaaactg tacgtattat
     6781 tgatggtgct tttgcagact acactggtaa gattacagaa attgataata acaaagtgaa
     6841 aatgattatc tctatgtttg gtaatgacac agttgcagaa gtaaacctaa accaaatcgc
     6901 agaattataa ccctgagaga ggctggagcc tctctttttt gtgcagttta ggagctaaag
     6961 ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact gtatctagaa
     7021 aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg tataagtgta
     7081 gaaatgaata ttaccttcat ttatgggaat tgtcggattg ggaccaagaa ggcatgctct
     7141 gcttacatga attgattagt agagaagaag gactggtaga cgatattcca cgtttaagga
     7201 aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag caggaaagtc
     7261 agaagcgta
//
LOCUS       DAVHSL010000079         7191 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000079 DAVHSL010000000
VERSION     DAVHSL010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.081"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            77..334
                     /locus_tag="VVR39_002035"
     CDS             77..334
                     /locus_tag="VVR39_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6031434.1"
                     /translation="MDIRKKIIELCIKINPHLEDHYFYDYEKMIDDLDFDSLTITQLV
                     IDIEEQFDIMLPPQKISMSEMETFGKIVDLVHKCITSKESR"
     gene            331..1521
                     /locus_tag="VVR39_002036"
     CDS             331..1521
                     /locus_tag="VVR39_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031435.1"
                     /translation="MMPQITQFLNNIKNNNEYYSNIINDATVLDDIPILNKNDIRLNP
                     DSIISECYSKKDLIHETTNGTTDYHPLDLYKTPQERVDLNFSLWKERRKFISASNIKS
                     VKIAVFYYSHDSLMNHDGSLKKVSGLIQVPMNRADDNQYIADLKYLIEEEIKWLIGPV
                     SIFLKYAKICKKYCIKFNVEYCECTSEYVPEVYRKEIEDVFKCKFLMQYSCHELWGIA
                     FTNSLEMYNVLKPLDNSIVEGLLRKEFTSKKLYSPVVTSLTLKAMPFIKYLLTDLVYF
                     DNGYIIPFGFRYTDMVKLKTDTIHCSIFDNLFGTLPFKFEPLEQYQIIYDAQNSEIVV
                     NVLNLEVTQGDIVCSVLKEYIKEHYKSSIKVSLRNCSKFFRDNLTGKMRGIINKENIN
                     NEIW"
     gene            1537..3042
                     /locus_tag="VVR39_002037"
     CDS             1537..3042
                     /locus_tag="VVR39_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU6031436.1"
                     /translation="MDNENEISKFFLSSENVKDMKTIANDILNMGLDFKLSEKVSQKK
                     MKEHDDLNFLSLEESIDNLPQLLEEFREKVIPYCTNFSSPNFMGFPDSGNSLGGLSGS
                     LLSDLLQQNLINASFCAPVATIMEINVIQWLRKVLGYSTSDVHNIMEVGGIVTYGGTG
                     SNSTAMLLARENKDGNTLELGVRNPRNYKVIVPKGIGHYSIASSLKWLGLGNNIIEVP
                     TENYRYNLKKLREALINHSNEIMAVVAYAGDSRTMTIDNLSEVADLVKTLTPNVWLHC
                     DACHGFSLAFSKKYKDRIKGIEKFDSISTDPHKVLGIPYCISVLLVKTPQSLNLIHSQ
                     SDLIMNENLALGQTTPFLGSKSWISLKLWLVAKHLGSEKIGAMVDKRIELTNYLQDLI
                     LKSSKLILLNRTDINSVMFMYIGDKHQEVSLSSVQNINNINKSIYDRLKDEGIYYLHQ
                     FPIIDNTETIYRGFELCPLRFMSGNPNLTIEELQKMVIEVENLGDRFVGES"
     gene            3046..4518
                     /locus_tag="VVR39_002038"
     CDS             3046..4518
                     /locus_tag="VVR39_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl--CoA ligase"
                     /protein_id="HEU6031437.1"
                     /translation="MSKELYNKFILTKEAGNIIYDGIEFGRDEIDRRILEISKILTAD
                     IVNLSQEAVAISCNKKINFFFLFLVVNCCDGVVMPVYARTPENKLQHICERYDINYMV
                     SDHEINLVGYSLIYHGSVFSEEYFIYECNKSFPKHEELKGIELLMLSSGTTGVSKAIS
                     LSLDNILSNTRSIQKYIIPTREDRCLIIKEITHSSSLISELINSLLSKNSVLLSDLIP
                     TVSSLGYLISTYGVTILYAIPDFLLFMNSIKFINNYRQLLGKLRLVQVVGAFCPPNYI
                     TDFHKNWPKIDLFNGYGLTEASPRVAVLGGEELYANPRCVGYPISGVGVHIDTSSNNT
                     QEGEICVTGPNIMVEYYLNEELTSKIKIGGMLRTGDIGYFDDKNRLYILGRKDNRYIK
                     SGKNIFPEEIESVVRKLPFISEVIVYPKIESGRLISILEYTICNDEEKDLNQEASEII
                     KLCKDNLEDYKIPDQYRKVKNIPHTSTGKVKRDRNNYYNE"
     gene            4511..6244
                     /locus_tag="VVR39_002039"
     CDS             4511..6244
                     /locus_tag="VVR39_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU6031438.1"
                     /translation="MNELCKKYVYQLQNELNQYCDNLEGIHVIAYGSNGSNDLSISSD
                     FDVCLIVNDDSFVAMNQRLICDFTKLFHFQENLPIDKDIPLSNKLIYLSSEVELFLDN
                     PPFISDSKKVKIEDIKKTKNFLTSRTMKQRLLLNILTTDSTVLFGDEDYVNNLKYRAW
                     EDIEKIIERAYNIKLTTKNENEFLNLLYQNPVSKASGEYYLGYKKEKRNVVKHLERNV
                     HRLAILNEKKVEDIIDLSENVNRLLLKDYSFLFPSETIKKMISTYPEKKSCSIKEVLS
                     SKLTIASNNFLITNGSLEGMNIIIANLVQNNIGYLTPTFWGYGDSAKRYNKSVISAPL
                     SDIYNYNVTEIDKISKSCELMIICNPNNPTTAILTKNQIENLLLNNPQTYFLIDESML
                     PYKYDFFNYTMIPFVEKYTNLIVCSSISKSLCAPGLRIGYICANEKIVKKLEKKVIPF
                     NVSNINQCIAEKILENFPLSLSICSDIESSFRQLDLFMEKYTTQKSEKACGFRLYQLK
                     AKYDGNKIIDILTERGFLIRNISASYPELGENWIRISNGTLSEIKDLMHIMKDIFEDF
                     DDKASDSYDKG"
     gene            6287..>7191
                     /locus_tag="VVR39_002040"
     CDS             6287..>7191
                     /locus_tag="VVR39_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031439.1"
                     /translation="MKLSSDLNILIRQLSYFIKDKEMLQQKIFGNFLDRFEEAYEQHF
                     FDIFDSLTGGIKISDVDWILGEEKLIKFLGRKNKNGQYLYVLPTNDGYLLRGSETYYH
                     YLSNVPYDYFKLIDKNIFIDGLKSTQNFLTEFIQYINSENSLTLKISLAFLDNLRNQI
                     LILLNAKFLVENDFKHGKYYVNFDSKLFKAIELFYSYYEKLFNFKHFILQPEDLVVIL
                     DILNSEIEALIPKLKNLDNNKVRKLTRVFRELDSIWEIFISLKYFFESENSLDVDNIS
                     EFCGIAYGGIEIPLVAHLFKEKNEIS"
BASE COUNT         2696 a          858 c         1246 g         2391 t
ORIGIN      
        1 acaaatatta tattgggtta taattaacaa caattaactc cacaaccaaa ttacaaactt
       61 tgagaaaggt aaaaatatgg atattagaaa aaaaattatt gaattatgca ttaagattaa
      121 tccgcattta gaagatcatt atttttatga ttatgaaaaa atgattgatg atttagattt
      181 tgattctctg acaatcacgc aattagttat agatattgaa gaacaatttg acataatgct
      241 tcccccacaa aaaatttcta tgtcagaaat ggaaacgttt ggaaaaattg ttgacttggt
      301 acataaatgt atcacgagca aggagagtag atgatgcctc aaatcacaca atttttaaat
      361 aatataaaaa acaacaatga atattattca aacatcatta atgatgccac agttttagat
      421 gatattccaa ttttgaataa gaatgatatt agattaaacc cagattctat tatttcagaa
      481 tgttacagca aaaaagatct tatacatgaa acaactaatg gcacgacaga ttatcatcca
      541 ttggatttat acaagactcc tcaagaaaga gttgacttga acttttcact ttggaaagaa
      601 agaagaaaat ttattagtgc ttctaatatt aagtctgtta agatagcagt tttttattac
      661 agtcatgatt cattaatgaa tcatgatggc agtctgaaaa aagtatcggg attgattcaa
      721 gttccaatga atagggctga cgataatcaa tatattgcgg atttaaaata tcttattgag
      781 gaagaaataa aatggctgat tggtccggtt tcgatattct tgaaatatgc aaagatttgt
      841 aaaaaatatt gtattaaatt taatgttgaa tattgtgaat gtactagtga gtatgtccct
      901 gaagtatata gaaaggaaat agaagatgta tttaaatgta aatttttaat gcaatatagc
      961 tgtcatgagt tatggggaat tgcatttaca aattcattag aaatgtataa tgtacttaaa
     1021 ccattagata attctatagt tgaaggtctg ctgagaaaag aatttacttc taaaaaatta
     1081 tatagtccag ttgttacttc actaactcta aaggcaatgc catttataaa atatttactt
     1141 actgatttgg tttactttga taatgggtat attatcccgt ttggctttag atacacagac
     1201 atggtaaaac taaaaacaga taccatccat tgttcaatat ttgataattt atttggaaca
     1261 ttaccattta aatttgaacc tttagaacag tatcagatta tctacgatgc tcaaaattca
     1321 gagattgtgg ttaatgttct aaatttagaa gtgacacaag gtgatattgt ttgctcggtt
     1381 ttaaaagaat atatcaaaga acactacaaa agttcaataa aagtttctct tcgaaattgt
     1441 tcaaaatttt ttagagataa tctgacagga aaaatgcgtg ggataataaa taaagagaat
     1501 ataaataatg aaatttggta ggaggcaaac tcatacatgg ataatgaaaa cgaaatttca
     1561 aagttttttc tgagttcaga aaatgtaaaa gatatgaaaa ctatcgcaaa tgacatttta
     1621 aatatggggt tggattttaa attaagcgaa aaagtttctc agaaaaaaat gaaagaacac
     1681 gatgatttaa attttctcag cttagaagag agtatagaca atcttccgca acttttggaa
     1741 gaattcaggg aaaaagtaat tccttactgt acaaattttt cttcccctaa ttttatgggt
     1801 tttcctgact caggaaattc attaggcggt ctttcaggta gtttgcttag tgatttatta
     1861 cagcaaaatt tgattaatgc atctttttgc gctcccgttg ctactattat ggaaataaat
     1921 gtaatccagt ggttacgaaa agttttagga tattccactt ctgatgttca taatattatg
     1981 gaagtaggcg gcatcgttac ctatggtggt acaggaagta attctacagc tatgctttta
     2041 gcaagagaaa ataaagatgg aaatactctt gaattaggcg taagaaaccc cagaaactat
     2101 aaggtaattg tgccaaaagg aattggtcat tatagtatcg catcaagttt aaagtggctg
     2161 ggattgggga ataatattat tgaagttcct acagaaaatt atcgctataa cttgaagaaa
     2221 cttagggaag cactaatcaa ccattctaat gaaataatgg cagtggttgc atatgctgga
     2281 gatagtagaa caatgactat tgataatcta tctgaagtag cagatttggt aaagacactt
     2341 accccaaatg tttggttaca ctgtgatgct tgtcacggat tttcattagc tttttctaaa
     2401 aagtataaag ataggataaa aggaattgaa aaatttgata gtatttcgac agatccgcat
     2461 aaagttttag gaattcctta ttgcataagt gttttgttag tgaaaacacc tcaatcgctt
     2521 aatctaattc actctcaatc agatttgatt atgaatgaaa acttggccct tgggcaaacg
     2581 actccatttt tgggaagtaa aagttggata tctctaaaat tgtggttagt agctaaacat
     2641 ttaggatcag agaaaatagg agcgatggta gacaagagaa tagagttaac gaattatttg
     2701 caagatctaa tacttaagag ttctaagtta atattattaa ataggacaga tattaattca
     2761 gttatgttca tgtatatagg tgataaacat caagaagtaa gcttatcatc agtacagaat
     2821 ataaataaca ttaataagag tatttatgac agactaaaag atgaaggaat atactaccta
     2881 catcaatttc caataataga taatacagaa accatataca gagggtttga attatgtcca
     2941 ttacgattta tgtctggaaa tcctaattta acaattgaag aactacaaaa aatggttata
     3001 gaagtagaaa atctagggga tagatttgta ggagagagtt aaaaaatgag taaagagctc
     3061 tataataaat ttattttgac aaaggaagct ggaaatataa tatatgacgg cattgaattt
     3121 ggcagggatg aaattgatag gagaattctc gaaatttcta aaatacttac tgcagatatt
     3181 gtcaacttat cacaagaagc agttgctata agttgtaata aaaaaataaa ctttttcttt
     3241 ctttttctgg tagttaattg ttgtgatggt gttgttatgc cagtgtatgc tagaacgcca
     3301 gaaaataaat tacaacatat ctgtgaaagg tatgacataa actatatggt ttctgaccat
     3361 gaaattaatt tggtagggta tagtttaata tatcatggga gtgttttttc agaagagtat
     3421 tttatatacg agtgtaataa atcatttccg aaacatgagg agttgaaggg gattgaattg
     3481 ttaatgctct cttcaggtac tacaggagtt tcaaaagcga ttagtttatc gcttgataat
     3541 attttatcta atactagaag cattcaaaaa tatattattc ctactagaga agataggtgt
     3601 ctcataataa aagaaatcac acactcgtcg tcattgatat cagaattaat aaatagtttg
     3661 ttatcaaaaa attcagtgtt gttaagcgat ttaattccga ccgttagttc attagggtat
     3721 ttaataagta catacggtgt gactatttta tacgctatac ctgattttct attgtttatg
     3781 aactctatta aatttataaa taattataga caattgttag ggaaattaag attagtacag
     3841 gttgtaggtg cattttgtcc tccaaattat ataacagatt ttcataaaaa ctggccaaaa
     3901 attgatttat ttaatggtta tggtttaaca gaggcctctc ctagagttgc tgtattagga
     3961 ggagaagaat tatatgcaaa tcctaggtgt gtaggttatc caatttcagg agttggtgtg
     4021 catattgata caagtagcaa caacacccaa gagggagaaa tttgtgttac tggtcctaat
     4081 attatggttg aatattactt gaacgaagag cttacttcta aaataaaaat tggaggtatg
     4141 ttaaggactg gagacattgg ttactttgat gataaaaaca ggttatatat tttaggcaga
     4201 aaagacaata ggtatataaa atcaggaaaa aatatatttc cggaagaaat agaatctgta
     4261 gtaagaaaat taccttttat atccgaagta atagtttatc ctaaaataga atctgggaga
     4321 ttaatatcta ttcttgaata tactatttgc aatgatgaag agaaagattt gaatcaagaa
     4381 gcaagtgaaa taataaaatt atgcaaagat aatctagaag attataaaat ccctgatcaa
     4441 tataggaagg ttaaaaatat cccgcacact tctacaggga aagtaaaacg tgataggaat
     4501 aattattata atgaatgagc tatgtaaaaa atatgtttat caattacaaa acgaactaaa
     4561 tcagtattgt gataatctgg agggaatcca tgttattgct tacggttcaa atggtagtaa
     4621 tgatttgtct atttcatctg attttgatgt ttgtcttatt gttaacgatg attcatttgt
     4681 tgctatgaat cagcggttga tatgtgactt tacaaagtta tttcattttc aagaaaattt
     4741 accgatagat aaggatattc ctttgagcaa caaacttatt tatctaagca gtgaggttga
     4801 attatttttg gataatccgc cgttcatatc agattctaag aaagttaaga ttgaagatat
     4861 taaaaaaacg aagaactttt taacttcaag aactatgaaa caacgtctct tactaaatat
     4921 tttgactaca gattctacag ttttatttgg tgatgaagat tatgttaata atctgaaata
     4981 tagggcatgg gaggacattg aaaaaataat tgaaagagcg tataatatta aattaacgac
     5041 caaaaatgaa aatgaattct taaatttact atatcaaaac ccagtatcga aagcaagtgg
     5101 agagtattat ttaggatata aaaaagaaaa aaggaatgtt gttaaacatt tagaaaggaa
     5161 tgttcaccga ttagcaattt tgaacgagaa aaaggtggaa gatataattg atttatctga
     5221 aaacgtcaat aggttactct tgaaagatta ctcattttta tttccttctg aaactataaa
     5281 aaaaatgata agcacatatc cagaaaaaaa atcatgcagc attaaagaag ttttgtcttc
     5341 taaattaaca atagccagta acaatttctt gattacaaac ggttctttag agggtatgaa
     5401 tattataatt gcgaacttgg ttcaaaataa tataggatat ttaaccccta ctttttgggg
     5461 atatggggat tctgcaaaaa ggtataataa atcagtgatt tcggcacctt tgtcagatat
     5521 ttataattat aatgttacag aaatagataa aatttctaaa tcttgtgagc ttatgataat
     5581 atgtaaccca aataatccga ctacggctat tttaacaaaa aatcaaatag aaaatcttct
     5641 tttaaacaat ccacaaacat attttttgat tgatgaaagc atgttgccat ataaatatga
     5701 tttttttaat tatacaatga taccatttgt agaaaaatat actaatttga ttgtttgttc
     5761 ctcaatatcg aagtcactat gtgctcctgg attaagaata ggctatatat gtgctaacga
     5821 aaaaattgta aaaaaattag aaaaaaaagt aattcctttc aatgtttcta atatcaatca
     5881 atgtatagct gaaaaaatat tagaaaattt tccgctctct ctaagtatat gttcagacat
     5941 tgagtcttca tttagacaat tagatttatt tatggagaaa tacactactc aaaagtctga
     6001 aaaggcgtgt ggtttcaggt tataccagtt gaaagcaaaa tatgatggta ataaaataat
     6061 agatatacta acggaaagag gttttttgat aagaaatata agtgcttcat atcctgaatt
     6121 gggtgaaaat tggataagga ttagtaatgg cacgttatca gagattaaag atttgatgca
     6181 cataatgaaa gatatctttg aagattttga tgacaaagcc agtgatagtt atgacaaggg
     6241 gtaggtgttg aaaataaaag atagtgcgga gattttgaat aataatatga aattaagtag
     6301 tgacttaaat attttaataa ggcaactctc ttattttata aaagacaagg aaatgttgca
     6361 acaaaagatt tttggtaatt tcttagatag atttgaagag gcttatgagc agcacttttt
     6421 tgatattttt gattcactta ctgggggaat taagattagt gatgttgatt ggattttagg
     6481 tgaagaaaag ttgattaaat ttcttgggag aaaaaataaa aatggtcaat acctctacgt
     6541 acttccaaca aatgacggct atttactcag aggttctgaa acatactacc attatttatc
     6601 gaatgtacca tatgattatt ttaaactcat tgacaaaaat atatttatcg atggcttgaa
     6661 atctacacaa aattttttaa cggaattcat ccaatatata aattcagaaa actctttgac
     6721 tcttaaaatc agtcttgcat ttctagacaa tttaagaaat caaattttaa tactcttgaa
     6781 tgctaagttt ttagtagaga atgattttaa acatgggaaa tattatgtga atttcgattc
     6841 taaactattc aaagctattg agttatttta cagctattat gaaaagctat ttaatttcaa
     6901 gcattttatt ctgcaaccgg aagatttagt tgtgatcctt gatattttaa actctgaaat
     6961 tgaagctttg attcctaagc ttaaaaatct agataataat aaagttagaa agcttactcg
     7021 tgtttttagg gaattagatt ctatctggga aatttttatt tctttaaagt atttctttga
     7081 aagtgaaaat tcattggatg tagataatat tagtgaattt tgtgggatag cttatggcgg
     7141 gatagaaatt cccttggttg cgcacctatt taaagaaaaa aatgaaatat c
//
LOCUS       DAVHSL010000080         7172 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000080 DAVHSL010000000
VERSION     DAVHSL010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.082"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(27..1019)
                     /locus_tag="VVR39_002041"
     CDS             complement(27..1019)
                     /locus_tag="VVR39_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031440.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1179..2933
                     /locus_tag="VVR39_002042"
     CDS             1179..2933
                     /locus_tag="VVR39_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031441.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     TLLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            2917..4638
                     /locus_tag="VVR39_002043"
     CDS             2917..4638
                     /locus_tag="VVR39_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031442.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSILTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVKGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            4649..5233
                     /locus_tag="VVR39_002044"
     CDS             4649..5233
                     /locus_tag="VVR39_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6031443.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            5233..5928
                     /locus_tag="VVR39_002045"
     CDS             5233..5928
                     /locus_tag="VVR39_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6031444.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIAGGLIWLK"
     gene            5916..>7172
                     /locus_tag="VVR39_002046"
     CDS             5916..>7172
                     /locus_tag="VVR39_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031445.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGKIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRREFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLCLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIK"
BASE COUNT         2569 a          965 c         1278 g         2360 t
ORIGIN      
        1 aaaaacatgg cttgtaaaaa attactttaa tcacaataat cgcatttaaa attgtgatgt
       61 ttgcaagcta aattacggac ttcacttgga agttttccct tgtatctttt ataatagata
      121 gaaaatttgc tggcagatga atatccaaca gattctgcta tctcttttat aggtagttca
      181 gtgtttaaaa gaagagtttc agctacattc attctttttc tttgagtgta ctctgtaatg
      241 ctttgacaat atttttcctt aaataaattt tttaatttag taccactcat tttagatatt
      301 ttttcaagcg tgccttgatt tacattcgtt gcaaaatgat catctaagaa tcttgctaca
      361 tcttcaagtg ctttatcatc atcaatttca attttatatt tttttctatt taagtatgtg
      421 tcaattacta tacttatcca ttcatttgcc tttgctttaa agaaaaaatc agcggcagga
      481 gcgtccatct tacaatttaa tatttccatt gccactcttt ctaaggcctt tgtaagtatt
      541 atttgattcg gttgaagcaa ggttgaataa aaagattctg gattaatgtt aatagatgct
      601 aaatgttttt ctattagctc ttttttaaaa ccaatggaaa cagcaagata acaacaattc
      661 tcgtgtaata aaaaaacaaa atcatctttt atattatcaa aatcaaaagt acataaagag
      721 tttgcggtaa tagtttgata cggattaaac ttttctccgt ttgcactgac aatgtaactt
      781 gaataaattg aaacatagtc tgacatacta taagtgctat tttgaactac ttcctctttg
      841 atataaaaat catgtatatc gataatgaag ctgcctcctt cataaaacca atataggcct
      901 tctgcataag ttgaattctc ttttttccaa caaaatgtat gacctgcact tgaatacttc
      961 tcattgtttt tacattcatc tactttcata taatctttta caaaatcata atatgacata
     1021 acacactatc ccttttagac aatattccaa ttagccttat taattcaaaa ctattgtatt
     1081 agtaattata acagatgtat aatagaaaag caatgataga tattatcaat taagcgaatt
     1141 tatatctaaa agggatatta aagaaaggag atatgcttat gaagatttac aaaaaactat
     1201 ttgcttatgt ccaagataag aaatatcttg gggttttggc cataattttt tctgctatat
     1261 ctgctgcact tacagtatat ggatattatt taatctacaa atttctagat aagttaataa
     1321 ttaattcaaa cttatccggt gcagagagta tagcattaaa atctgttatt acactaacaa
     1381 gtggagcgat attttatttt gtctcaggaa tgttttcaca tatcttggga tttaggcttg
     1441 aaacaaattt aagaaaaagg ggaatcgatg gtctggaaaa agcaagtttt aggttctttg
     1501 acttaaatcc atctggtcaa ataagaaaga tcatagatga taatgcagca caaactcatc
     1561 aggtggtagc tcacatgatt ccagatagct ctcaggcaat agtcacacct atacttgtcc
     1621 ttgtactagg ctttatagta agtataaggg ttggtataac tttgcttgct cttactataa
     1681 ttggcggctt aattttaggg gcaatgatgg gcgagcaaga atttatgaag atataccaag
     1741 aatccctatc taaactaagt gctgaaactg ttgagtacgt gagaggaatg caagttgtaa
     1801 aaatatttaa agcaaatgta gagtcattta aaagctttta caaggctata aaagattact
     1861 caaagtatgc ttatgattat tccctatctt gtaaaaggcc ttatgttttg tatcaatggt
     1921 tattttttgg actgattgca attttaatta ttcctatagt ttattttatg actagcttag
     1981 ctagcgcaaa ggtgatttta cttgagctta tcatgatttt atttttatca ggagttctct
     2041 ttgtttcatt catgagaatg atgtggtact ccatgtatat ttctcaagga aattatgcag
     2101 tagatacttt agaggcgctt tacgaagata tgcaaaaaga caaattagtg catggtaatg
     2161 tcaataattt taaaaactat aatatagaat ttgagaatgt tagctttgct tataatgata
     2221 aagctgtcat tgaaaattta tcctttaatt tagaagaagg aaagtcctac gcacttgtcg
     2281 gttcatctgg atcaggcaaa tcaacagtag caaaacttat atcaggtttt tacaatgtta
     2341 atgaaggaag cataaagata ggcgggatag caataagtga atattctgac gaagccttaa
     2401 ttaaagccat ttcctttgtt tttcaagatt caaaattatt caagaagagc atttatgata
     2461 atgtagcttt agctaataaa gatgcgacga aagatgacgt tatgagagcc ttaaaattag
     2521 caggatgcga tttaatatta gacaaattcc cagaaagaga aaatacaatc ataggctcaa
     2581 aaggtgttta tttatccggt ggagaaaaac aaagaattgc aattgctaga gcaattttaa
     2641 aggattccaa aattattatt atggatgaag catcagcatc tattgaccca gataatgagt
     2701 ttgaattgca aaaagctttt aaaaatctta tgaaggataa aacagttatc atgattgcac
     2761 acaggctatc tacaattaaa gaccttgatg aaattattgt catggatagt ggaaaaatta
     2821 tagaaagagg gtctgacaaa gaattaatgt caaaagatac aaggtataag agcctgcaag
     2881 agatgtttaa cagtgcgaat gaatggaggg tttcaaatga aagagtttta taaaaaaaga
     2941 tttgctctta cagatggagg agcaagaaat ttaagtaaag caacactggc ttcatttttc
     3001 gtttattgta taaacatgct tcctgccata ttacttatga tttttgctca ggaagttttg
     3061 gaaaatatgg gcaaaagcaa tggcttttat atagtattct caattttgac tttgatagca
     3121 atgtatattt tgctttctat cgaatacgat aaattatata acacaaccta tcaagaaagt
     3181 gcagatttaa gaataaggac agcggagaat ttatcaaaat tacctctatc ttacttttct
     3241 aaacatgaca tttccgacat ttcacaaaca atcatggctg atattgaagg catagagcat
     3301 gcaatgagcc actcaatacc aaaggtgggc ggcatggtac tgtttttccc attaatatct
     3361 gtaatgatgc tagcgggcaa tgtcaagatg ggtttagctg taattattcc atctatttta
     3421 agctttatat ttataccttt atctaaaaaa tatcaggtta agggacagaa tagatattat
     3481 gatgtcttaa gaaaaaactc agaaagcttt caagaaaata tcgaaatgca aatggagatt
     3541 aaagcatata atttatcgaa ggatattaaa gatgacttat ataaaaaaat ggaagatagt
     3601 gagagagtac acttaaaggc ggaagtaact acaattttaa ctttgtctat atcttcaata
     3661 tttagcttta tatctcttgc tgttgtgata tttgtcggcg taaatctaat tattaataaa
     3721 gagataaatt ctctctacct tataggatat ttactagctg ctatgaagat aaaagactct
     3781 ttagatgcat ctaaagaggg cttgatggaa atattttatt tatcgcccaa aatagaaaga
     3841 ttaaaagaaa ttcaaaatca agatctacaa gaaggcgatg actatagctt aaaaaaattt
     3901 gatattgatc taaaagatgt tgagtttgcc tacaataaag acgcaaaagt tttaaatggt
     3961 gtaagtttta aagctaagca gggagaggtc actgctttgg taggtgcaag tggctgcggt
     4021 aaaacaacta tcttgaaact tatatcaaga ctttatgatt atgacaaggg acaaatctta
     4081 atcgatggca aagatataaa agaaatatca acagaatctc tttttgataa ggtctctata
     4141 gttttccaag atgtggttct ctttaatcaa agcgttatgg aaaatattag aatcggaaag
     4201 caagatgcaa gtgacgaaga ggttaaaaga gcagcaaaac ttgcaaattg cacagatttt
     4261 atagaaaaaa tggataaagg tttcgataca gttattggtg agaacggagc tgagctatca
     4321 ggaggagaaa gacaaagatt atcaatagcc agagccttct taaaagatgc gccgatattg
     4381 atcttagatg agataacagc aagccttgat gttaacaacg agaaaaagat tcaagagtct
     4441 ttaaataatt tagttaaaga taaaactgtt gtaatcattt cacatagaat gaaatccata
     4501 gaaaatgcag acaagatagt agttcttcaa aacggaagag tagaaagcga aggtaagcat
     4561 gaagagcttt tacaaaaatc aaaaatttac aaaaatttaa tagaaaagac aaaaatggca
     4621 gaagaattta tttattagga ggactacaat ggataataaa aaattaaaag taaaagattt
     4681 agtaagtatc ggtgtttttg gcgtaattta ttttgccttc atgtttggag ttggtatgat
     4741 gggcttgatt ccaatattgt tcttaatata cccgacagta ttagccatag ttgcaggaac
     4801 tgttgttatg ttatttatgg ctaaggttca aaagccatgg gcactattta tatttggtat
     4861 gatatcacca cttgtgatgt ttgcagctgg tcatacctac gtagttgtgg ttttatcact
     4921 tatagtaatg ataatagcag aattaattag aaagattggt aattataatt catttaaata
     4981 caatatgctt tcttatgcaa tcttcagcac atggatatgt agctctttaa tgcaaatgct
     5041 tttagcaaaa gaaaaatata tggagtggtc tttgatgacg atgggaaaag attatgttga
     5101 tgtattagaa aagttaataa cttatcctca catggcttta atagccttag gtgctttctt
     5161 aggaggaatt cttggagcat atataggcaa ggctctattg aaaaaacact ttgaaaaagc
     5221 aggcatcgta taatgcctac tttttcttca aatgctccct ttaatcccaa tccgatctct
     5281 aagatattag tcgtatttat cacaggctta actgttatgc atagcataaa catccgtttt
     5341 gagctggcaa ttgtttgtct tattggtatt ttgctttatt tgaatggata caaaaaaaca
     5401 cttttcaaat ggattatatt gtgtgggata ctttactcct tgcctaattt tatggtatta
     5461 tctgaattaa accctatagt taagatgttt ttgagtatac ctattgttat tagaatgttt
     5521 attttaccat ttatggcagc aagctttatg ataaagacct cggatgtagg cgcaataatt
     5581 tcatcgatgg ataagcttaa gatttcaaag aatgtatcca tacctattgc ggttatgttt
     5641 agattcttcc catcttttaa ggaggagaag aaaaacatca aaatggctat gagagtaaga
     5701 gggataaatt ttaaaaaccc agtcaaatat cttgaatatg tttctgtgcc actactcatt
     5761 atatcatcta atatatcaga tgacattgca aaagcggcag aaacaaaggc aatagaaaat
     5821 ccaattgcca agaccagata cattcgcgta aagatacagc taattgattt tgtttatgtt
     5881 ttagcggttg ctggacttat tgcgggaggc ttaatatggt tgaaataaaa aatttaagtc
     5941 ttgattatgg tgaagagcat atattagatg atatatcact atccatagcc gagggagagt
     6001 gcgtgctatt tacaggaaaa agtggaaatg gtaagtcatc tttaataaat tcaatcaatg
     6061 gactagctgt aaggtatgat aacgcaaaga caaagggcaa aataattatt gatggtaaga
     6121 atataaaaaa tttggaactt tatcaaatct caatgcttgt ttcaactgtt tttcaaaatc
     6181 ctaagaccta tttttttaat gtcaatacga cattagaatt attattttat ttggaaaata
     6241 tcggtcttgc aagagaagag atggacaggc gtttgaagga tatgcttgag atattcccga
     6301 taaaaaatct tttgaacaga aatatattta atctatccgg cggtgaaaaa caaattcttt
     6361 gcattgcagc ttcttatata gcaggtacaa agattatagt tatggatgag ccttcatcga
     6421 atttagatat taaaagcata agtgttttgg caaagatgct aaagatatta aaagagaaag
     6481 gcataagcat aattgttgca gagcatagaa tttattattt gatggacata gttgaccgtg
     6541 tatttttaat agataaagga aagcttaaaa aaacttatac tagaagggaa tttttaaagc
     6601 tagataaaaa tgaattaaat gctttaagtt taagagataa agaattaagt aaattaaaag
     6661 ttccttattt aaaagaaggt ggagagtatc agataaaaaa tcttagctac aaatttactg
     6721 atgatgagtg tttaagctta aaagatattt cgttcaagct tgggaaaatt tatggcataa
     6781 taggatccaa cggacgagga aaatcaacgc ttttaagatg tttaataggt cttgagaaaa
     6841 aatcaaaaga agaaatttat tttaagggag agaagctatc taaaaaagaa agactcaaaa
     6901 actcttcact tgttatgcaa gatgtaaatc atcaattatt cacagatgaa gtattcaacg
     6961 agcttagatt aggagtaaag aattttgatg aagaaaaggc gaaaatcatt ttaaaagatt
     7021 tatgcctgga cgaatttatt gaaaggcatc cgatgagttt atcaggaggg caaaagcaaa
     7081 ggcttgcaat agcatctgtt atgtgcaaga attctccatt tgtctttttt gacgaacctt
     7141 caagtggtat ggattattcc aatatgataa aa
//
LOCUS       DAVHSL010000081         6669 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000081 DAVHSL010000000
VERSION     DAVHSL010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.083"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..98
                     /locus_tag="VVR39_002047"
     CDS             <1..98
                     /locus_tag="VVR39_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU6031446.1"
                     /translation="YDLEPMAQQVIPKAAFGYIASGAGDTFTSFQ"
     gene            226..1716
                     /gene="lysS"
                     /locus_tag="VVR39_002048"
     CDS             226..1716
                     /gene="lysS"
                     /locus_tag="VVR39_002048"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU6031447.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            2340..3476
                     /gene="lctO"
                     /locus_tag="VVR39_002049"
     CDS             2340..3476
                     /gene="lctO"
                     /locus_tag="VVR39_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU6031448.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      3728..3816
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4031..4699
                     /locus_tag="VVR39_002050"
     CDS             4031..4699
                     /locus_tag="VVR39_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU6031449.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(4849..4935)
                     /locus_tag="VVR39_002051"
                     /pseudo
     CDS             complement(4849..4935)
                     /locus_tag="VVR39_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            5026..5808
                     /gene="thiM"
                     /locus_tag="VVR39_002052"
     CDS             5026..5808
                     /gene="thiM"
                     /locus_tag="VVR39_002052"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6031450.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            5810..6439
                     /locus_tag="VVR39_002053"
     CDS             5810..6439
                     /locus_tag="VVR39_002053"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6031451.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
BASE COUNT         2108 a         1153 c         1428 g         1980 t
ORIGIN      
        1 cctatgattt ggagccaatg gcgcaacaag ttattcctaa agcagcattt ggctatatcg
       61 ctagtggggc gggagatact ttcacttctt tccagtgatt ttagcgtcag gttcttttta
      121 gtttttaaag attatccgtg aatttcttgc ttatttatga taaaatgggg gtatcgcaaa
      181 aaatgactca tcgtattcaa ttttgagtaa aattaggagg atcccatgtc tacagaacat
      241 atggaagaac taaatgacca gcagatcgtt cgccgtgaaa aaatggctgc gctccgcgaa
      301 caaggaatcg atcctttcgg aaaacgtttt gaacgtactg caaattcaca agaattaaaa
      361 gataaatatg ccaacctcga taaagaacaa ttacacgata aaaacgaaac agctactatc
      421 gcaggacgct tggtaaccaa acgtggtaaa ggaaaagttg gttttgccca ccttcaagac
      481 cgcgaaggcc agattcagat ctacgttcgt aaggatgctg tcggtgaaga aaactacgaa
      541 atcttcaaaa aagcagacct tggtgacttc cttggtgtcg aaggtgaagt gatgcgtacg
      601 gatatgggag aactctctat caaggcaacc cacatcacac acttgtctaa ggctcttcgt
      661 cctcttcctg agaaattcca tggtttgaca gacgttgaaa caatttaccg taaacgttac
      721 cttgacttga tttctaaccg tgaaagcttt gaacgctttg tcactcgttc aaaaatcatc
      781 tctgaaatcc gtcgttacct tgaccaaaaa ggattccttg aagtggaaac acctgttctt
      841 cataatgaag ccggtggtgc tgctgcccgt ccatttatca cccaccacaa tgcccaaaac
      901 attgacatgg tgcttcgtat cgcgactgag cttcacttaa aacgccttat cgtgggtggt
      961 atggaacgtg tctatgaaat tggccgtatc ttccgtaacg aaggaatgga cgctactcat
     1021 aaccctgagt ttacttctat cgaagtttac caagcttatg cagacttcca agacatcatg
     1081 gacttgacgg aaggcattat ccaacacgct gctaaatcag ttaagggcga tggcccagtc
     1141 aactaccaag gtactgaaat caagattaac gaaccattta agcgtgttca tatggtggat
     1201 gctatcagag aaattactgg tgtcgatttc tggcaagaca tgactttaga agaagctaaa
     1261 gctatcgctg ctgagaagaa agttccagtt gagaaacact acactgaggt tggtcacatc
     1321 atcaatgcct tctttgaaga gtttgttgaa gaaactttaa tccaaccaac ctttgtctat
     1381 ggacatccag tagctgtatc tccactcgct aagaaaaatc ctgaagacca acgctttact
     1441 gaccgtttcg agctctttat catgactaag gagtacggta atgcctttac tgaactcaac
     1501 gacccaatcg accaacttag ccgttttgaa gcccaagcta aagccaaaga acttggtgat
     1561 gatgaagcga caggaatcga ctatgactac attgaagctc ttgaatacgg tatgccacca
     1621 acaggtggtt tgggaatcgg tatcgaccgt ctctgcatgc tcctcactga tacaacaact
     1681 atccgtgatg tattgctctt cccaacaatg aaataaattc ttatcctctg gctcttacca
     1741 gaggattttt tgattcaaaa agagactgaa tttaaggaga aaatgaagtg tagtatattg
     1801 aagttgaaat agtacacttt gatttctaag acattgttag aaattggttt aaattcccta
     1861 agcaatttgt gcatgtttta tttcatttta cgatagtacg ctgaaactgt tcaaaaagta
     1921 ctagaaattg acttggattc cccaattgat ttgttcagat tcactataaa taaaaaatta
     1981 ataagtggga taggaagtta gcgtcaacta ggatagtatc ttgcttaaac agtatatatg
     2041 ggactgatat aagtccatag gtcctattag aggatgttct ggtgtcttat tcacttgttt
     2101 tttatagtat tagtagatag aatcagcaaa taaaaaagta gttcaaatgc ctggcagcaa
     2161 aaaatctcaa cgattcactt aatatagact aaggtttaga gtttaaggaa agtagggcta
     2221 gtatattgta tgaaaaaata agatggtttt taagcaaaac tcttgaaaat gattgaaaaa
     2281 agagttatta tagttgtata gtaaaaagca aacgcttact taatcgagga ggacagttta
     2341 tgtcatacaa aacaagcaat gcagaaggtc atgtagactt catcaatacc tatgatttgg
     2401 agccaatggc gcaacaagtt attcctaaag cagcatttgg ctatatcgct agtggggcgg
     2461 aagatacttt cactttaaga gagaatatcc gtgcctttaa ccacaagctc atcgttcctc
     2521 atacactttg caatgtagaa aatccaagta cagagattga atttgcaggt gaaaaactat
     2581 cttctccaat cattatggca cctgttgcgg ctcataaatt ggcaaatgaa cagggggaag
     2641 tggcgactgc gcgtggtgtg catgagtttg gttctcttta tacaaccagt tcttactcta
     2701 ctgttgacct tccagagatt tctgaagccc ttcaagggac accccattgg ttccaatttt
     2761 actttagtaa ggatgacggt atcaaccgcc acatcatgga ccgtgtgaag gctgaaggtt
     2821 ataaagcgat tgtcttgacg gcagatgcta ctgtaggggg gaatcgtgaa gtggataagc
     2881 gtaatggttt tgtcttccca gttggcatgc cgattgttga agaatacctg ccagaaggtg
     2941 ctggtaaatc aatggacttt gtttacaaat cagctaaaca acgcttgtct ccacgcgatg
     3001 tagaatttat cgctgaatac tctggtcttc ctgtgtatgt caagggacca caatgccgtg
     3061 aggacgttga acgttcactt gctgcaggag cttctggtat ctgggtaacc aaccacggtg
     3121 gtcgtcaaat cgacggtgga ccagctgcct ttgactcgct tcaagaagtg gcagaagcag
     3181 ttgatagacg tgtgccgatt gtctttgact ctggtgttcg tcgtggtcaa cacgtcttta
     3241 aagccttggc ttcaggagca gacttggtag ctattggtcg ccctgttatt tatggcttgg
     3301 ctctcggtgg tagtgtcggt gtgcgtcaag tctttgaaca cttgaatgcg gaattgaaga
     3361 cagttatgca attgtctgga gctcagacca ttgaagatgt caaacacttt aagctccgtc
     3421 acaatccata caacccaacc ttcccagttg accctcgtga cttaaaattg tattgataaa
     3481 acagattgcc ttcactgaat gtggaggttt ttcttcgtgt attggaagaa taaatcgcta
     3541 tcgaaaacta tagtaaaatg aaataagaat aggacaaatc aatcaggaca gttaaatcga
     3601 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta ctatataaag
     3661 atatttttcg gtcaaatatc ttgctagggc tttcattttt tgctatactg gttcagtaat
     3721 taaataatag agacatttgg ggtgctttaa gctgagatga tacccattga acctgataca
     3781 gttaagactg gcgaagggaa atgtgaaacg ttttttcgta tggcgaaatg aacgatctaa
     3841 tcttgtaagt caactctaat tcttgattgt aattggagtt ttttgtttat ataaactgga
     3901 taggcttgtt tagttagctc tctgcaaatg ctctcgatgt gctttaaaag gatcaagtgg
     3961 aattacgatt ttgcttgata tttcttgctg ttttattaat tactaacaag taaagagagg
     4021 agaagtaaat atggaaacac aagactatgc atttcagcca ggtttgactg ttggagaatt
     4081 attaaaaagc agtcagaagg attggcaggc tgcaatcaat catcgttttg ttaaggaact
     4141 ttttgcgggg acaattgaga ataaggtctt aaaggactat ctgattcaag attatcactt
     4201 ctttgatgcc ttcttatcca tgctgggtgc ctgcgtagct cacgcagata aacttgaatc
     4261 caagcttcgt tttgccaagc aactaggctt tcttgaagca gatgaagatg gttatttcca
     4321 aaaggctttt aaagagttaa aagtagcaga gaatgactat ctagaagtga ctttgcaccc
     4381 tgtaacaaaa gcctttcagg atctaatgta ttcggcagtg gcttcatcag actatgccca
     4441 tcttttggtc atgctggtca ttgcagaagg tctctattta gactggggtt ctaaagattt
     4501 ggctctacct gaagtctata ttcattcgga atggatcaat ctccacagag gtcctttctt
     4561 tgcagagtgg gttcaatttc tggttgacga actcaatcgt gtcggtaaaa atcgagaaga
     4621 tttgacagaa cttcagcaac gctggaatca agcagtcgct ttagaattag ctttttttga
     4681 tattggttac gatgtctaga gaaggctcat gatatttaca aatttgatga ggtaagactc
     4741 ttcgaaaatc tcttcaaacc acgtcagttt caccttgccg taggtatggt tactgacttc
     4801 gtcagttcta tccacaacct caaaacagtg ttttgagctg acttcgtcag tcttatctac
     4861 aggttcaaag cagtgttttg agcaacctgc ggttagcctc ctagtttgct ctttgatttt
     4921 cattgagtat aaatcattca acgtaaatga aaaaaatttc ttaacgaaag atagagataa
     4981 atcgaaatca gtagatcgta taaagtgaaa aggaaggatt tcaatatgac aagtttaaaa
     5041 ttattaaaag aaaaagcacc attggtcatt tgtataacca atgatgtagt aaaaaatttc
     5101 acagcaaatg gattagtagc actgggcgcc tcaccagcca tgagtgagtt tccagcagat
     5161 ttagaggatt tgttaaagta tgctggtggt ttattaataa acataggaac attgacagat
     5221 gaaaattgga aattatacca agctgctctg aaaattgcgg agaaatataa tgtcccagca
     5281 gttttagatc ctgtagcctg tggagcagga gaatatagaa aaaaagtagc agatgatcta
     5341 atcaacaatt ataaactagc agcgattaga ggaaatgctg gcgagattgc ctctttagta
     5401 ggaatagatg tggcatctaa aggagtagat agtgcgggcg tagataatat tgacgaaatt
     5461 gctctagcag caaatgagaa gttcaatatt ccaatagtag taacaggtga agtggatgcc
     5521 attgctgtta atggagaagt ggtaacgatt cataatggta gtgctatgat gccgaaagtc
     5581 attgggacag gatgcttatt aggagctgta gtagcaagct ttatcggact agaaaaaggt
     5641 caagaattga aatcattaga aacagcaatg ttagtttaca atatcgctgg agaaatggca
     5701 gaaaaacgtc caaatggaca tcttcctggg acatttaaag ttgaatttat aaatgcctta
     5761 tacgagatta cagatgaaga tgtaaaggaa ttcaaaagag tgaagtaaga tgtttcataa
     5821 agaattacta aaactatatt ttatttgtgg aacgactact tgccaaggaa aaaatctata
     5881 tacagtcgtt gaggaagcct taaaaggtgg tataacctta tttcaatttc gagaaaaagg
     5941 tgagggtgct ttagaaggct tagaaaaact tgagctagct atccaaatta aagaactttg
     6001 taaaaaatac aatgttccat ttatcgttaa tgacgatata gatttagcaa tggaaattga
     6061 cgctgatggc gtacatgtag gtcaagatga tattggtgtt gatgaaatta gaaaattgat
     6121 gccagataaa ataattggtc tttctataaa aaacgaggaa gaatttcaac aatcaaaagt
     6181 tgaatatgta gattatgttg gtgttggtcc tgtatttgat acccagtcaa aggatgatgc
     6241 tggtggtgct ataggttatg aaggtgttaa attgatgaga aaactattgc cacaaatgcc
     6301 tttagttgca attggtggga tacagacgaa acatattaaa gacattataa agaccaatat
     6361 ggatggcgtt tcaatcattt cggcaatatc gtatgcaaaa aatatagaaa aaactgttcg
     6421 ggaaatgagt gaacaataga tatctatcct tggattctaa gtaagtagga ttttcctttt
     6481 ttaaaaagct atgtccagat tcagcttgaa tggctaattc atcaaacagg tcatttgttt
     6541 tttgcaaaag aaagatctgc tgtctttgtg agtgcaaggc tgtatttcca gttcaatttc
     6601 ttgaactagt ataaaatgtg tgttataata atcacataat taaataataa agacatttgg
     6661 ggtgcttta
//
LOCUS       DAVHSL010000082         6516 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000082 DAVHSL010000000
VERSION     DAVHSL010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.084"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..814
                     /locus_tag="VVR39_002054"
     CDS             <1..814
                     /locus_tag="VVR39_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6031452.1"
                     /translation="LLLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNY
                     AYRRVHLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQ
                     FEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIACNLSTSPNLEQVQTMLE
                     QAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGIL
                     KSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGLIPVQYRTKSFG"
     gene            complement(942..1145)
                     /locus_tag="VVR39_002055"
     CDS             complement(942..1145)
                     /locus_tag="VVR39_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031453.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCSNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1138..2220)
                     /locus_tag="VVR39_002056"
     CDS             complement(1138..2220)
                     /locus_tag="VVR39_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6031454.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2346..3128)
                     /locus_tag="VVR39_002057"
     CDS             complement(2346..3128)
                     /locus_tag="VVR39_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU6031455.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3128..4471)
                     /locus_tag="VVR39_002058"
     CDS             complement(3128..4471)
                     /locus_tag="VVR39_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU6031456.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4570..5886)
                     /locus_tag="VVR39_002059"
     CDS             complement(4570..5886)
                     /locus_tag="VVR39_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU6031457.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6079..>6516
                     /locus_tag="VVR39_002060"
     CDS             6079..>6516
                     /locus_tag="VVR39_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6031458.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFAS"
BASE COUNT         1897 a         1272 c         1421 g         1926 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccattt ttatcgaaca
      121 caagggaaat tatgcttatc gtcgggttca tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaag gcttgatgaa agtactcaat ttacaagcta aaatgcgaca
      241 gaaacgaaaa tattcttctc ataaaggaga cgttggtaag aaagcagaga atctcattca
      301 aggccaattt gaaggctcta aaacaatgga aaagtgctat acagatgtga cagaatttgc
      361 cattccagca agtactcaaa agctttactt atcaccagtt ttagatggct ttaatagcga
      421 aattatcgcc tgtaatcttt caacttcacc caacttagaa caagtacaaa caatgttgga
      481 acaggcattc acagagaagc actacgagaa tacgattctc catagtgacc aaggctggca
      541 atatcaacac gattcttatc atcagtttct tgagggtaag ggaattcaag catccatgtc
      601 acgcaaggga aacagccaag acaacggtat gatggagtcc ttctttggga ttctgaaatc
      661 ggaaatgttt tatggctatg agaaaacatt taaatcactt aatcaattgg aacaagctat
      721 tgtagactat attgattact acaacaataa acgaattaag gtaaaactaa aaggacttat
      781 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggggc
      841 agttcattct acacccacta ttatgcgttt tattgtggga agattttcct cattttctag
      901 tgaaattgaa ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc
      961 attgttgttt cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta
     1021 tcattccaga cacttagggt tagattactg cagccaattt ctttagcata atagcagaaa
     1081 aatgacaata aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta
     1141 atcaaaataa agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac
     1201 aacaccgcag tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac
     1261 agagaagcac atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc
     1321 atggacatcc ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc
     1381 tttttcgatg acctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat
     1441 aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg
     1501 gtctggtttg ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac
     1561 acccaggtca aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg
     1621 tggattcgca gcattatcac cagtcaagac catggtatca aagctcattt cataaccttc
     1681 acgtttcatg gcaaagtcga tttgtgcgat gatatctgtc tcagtcttat caagagaaat
     1741 attgtcaaaa ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg
     1801 cacttcatca gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttgtcaaa
     1861 ctcagcagtc tcaaaaactg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa
     1921 ctcaacagcg acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg
     1981 attttcagaa tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac
     2041 ttcaagagct gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg
     2101 gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac
     2161 gacagcgacg tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat
     2221 atgctacctt ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa
     2281 gggtaaaaga aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc
     2341 tttgtttaag aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg
     2401 ctgagaatgt cctcataggc agggagttgg atgtcctgac catatttctt cttgagggca
     2461 gtagtaacta ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag
     2521 gaaccaaaga cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt
     2581 ccatagacaa cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga
     2641 ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata
     2701 aaacggttat tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt
     2761 tttcctgaag cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga
     2821 actacaccgt cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct
     2881 gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt
     2941 tcatcaaagt catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca
     3001 gccacatact tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg
     3061 tagaggtggg caatgttgag ctgatagggg taattgctat cttttgagga aagtgaagta
     3121 taaaccatta gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt
     3181 ccagcatggc agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg
     3241 tcttgagaac ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca
     3301 ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt
     3361 ccatgtcagt gatttgctca aagtctgcat cccagatcca gctagtgtca attccatctg
     3421 catagttggc attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt
     3481 cgatagcttg ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac
     3541 cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga
     3601 tgagttggga atctgcgccg aggaaacggg cgatggccac agcagctagg gcgttataga
     3661 tattatagag cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc
     3721 gattgttggt caactcaacc agttttgtca aacgatagtc gagatcagga cgtttacatc
     3781 cacaaccttc acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga
     3841 tgccttggca gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc
     3901 ctttttccaa gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa
     3961 gtggactgtc tccgttaagg agaacagtag cagttggaac ttttcgaatg gcatccaata
     4021 tcatgttata ggtagtatag atttcaccga aacggtccat ctggtcacgg aaaatattag
     4081 taataacaaa taagcttggc tggatatagt cacagatacg agatagactg gcctcgtcga
     4141 tttctaggac ggcaatattt ttcccagttt tagaagattt ggctgttaag aaggttgtcg
     4201 caattcctgt aatcatgttg gcaccgcttg ggttggtcag aacttgacca taaacttctt
     4261 ttaaaatacc gacagtgagg gcagttgtca aggtttttcc gttggttcca gtgaccacga
     4321 caatctcgta gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt
     4381 tacctgggag cgtacttcca cggccaagac ggcttaaaat gaagtgggaa gaacgcccag
     4441 caagaaggcc caaagtagtt tttaagttca tgtttctatt atatcataaa agaggagaaa
     4501 gacagatttg agattccgca gaagtaaaaa cagcccaaag agggctgttc gatacgatta
     4561 aatctcaact taaatcgcaa acaagtcatt caagttctca gccaaggttg ggtgagtgaa
     4621 gatttgtttt gtgaagtaag tgtaaggaat cttgttgtcc atagcaacag tgatgatgtt
     4681 gatgatttct tgagaacctt ctgagaagat gcttgcacca agaatttctt ttgtttcagt
     4741 attaacaaca gctttgaaag ctccgcgaag gtctccattt acgtgaccac gaggcatggc
     4801 tgcaacaggg atttctttca ctgcgtatgg aagtttcaaa tcagctgctt ggctttcagt
     4861 caaaccaact tgtgaaagtg caggtgtgat gaacatagta tttggcacat tgagacggtc
     4921 ctcaagtgtg tagctgccat ctccagcaag gtagctgtaa acaacacgga agtcatcaag
     4981 tgaaatgtaa gtaaattgaa gaccaccgtt gacatctcca actgcaaaga caccaggaac
     5041 gtttgtttga cagtgtttat ctactttaat agcgccacgt tcagttagtt caatatctgt
     5101 attttcaagt tgaagtggtt ctacatttgg tttgcgtcca gttgcgtaga gaagggcgtc
     5161 gaaacggtaa gtttcgtctt cagttacgac aagcacttgg tcaccgtcgt ttttaatttc
     5221 agtagtatgg atattttgaa gcaattcaat accgtcttct tccatgtatt gtttagcaag
     5281 agctgcgatg gaaggttctg cacgaggtag gaatgtatcc aaggcatcta ggactgtaac
     5341 cttgcttcct agtttattgt aaaggccagc aaattcaaga ccgatatttc cgccaccaag
     5401 gactccaagt ttttcaggca atttatccaa gctttggata cctgttgagt caaagatgtt
     5461 tttgcttgta gcaagtccag gaattggcaa gacgtttgaa acagcaccag tgttgatgac
     5521 gattgtttca gcagtcagtt ctttcttttc atcaccagct tggatttcga tgactttatt
     5581 tgaaaggaag tgagcttccg catcaaagat atctacgcct gtaccagcaa cagtcgcata
     5641 gtttttaccg ttgaggcgac cagtgatcgt gtttttagta gcaatcactt cttcaaaaga
     5701 caagtccttt tcagcagcaa ctagcaaggt tttagttggg atacaaccaa tgttgataca
     5761 agttccaccg tacatagcct tgctgcgttc aacgagggca acttttttgc cagctgaagc
     5821 caatttacct gctagtgttt taccagcttt accaaatcca ataacaatta aatcgtatgt
     5881 taacatttat cttcctccta ttcgaatttc attctagcac aagaaaaaaa cttttgcaca
     5941 attctgctac ggaaaagaca gaaaaagata aaaacgcttt ccagacaaaa aactagtaat
     6001 tttttgacaa gcttgataaa ctaaaatcct atctattttt atataagaaa gaataaatgt
     6061 tcgaaaatag gaggttttat gaaatcgaat cgttatatta ttgcctttgc tggggtcatt
     6121 ttacacttaa tgctgggttc gacttatgct tggagtgttt atcgtaaccc tattattgaa
     6181 aaaacgggat gggatcaggc ttctgttgcc ttcgccttta gtctagcaat cttttgtttg
     6241 ggcttatcgg ctgcatttat ggggcgtttg gtagaaaaat ttggtccgaa agtcatgggg
     6301 agtctatctg cttttctata cgcaggtgga aatatcttaa caggatttgc aatagaccgt
     6361 caggaactgt ggttgttgta tctagcttat ggcattttag gtgggcttgg tttgggagca
     6421 ggctatatta cccctgtgtc aacgattata aaatggtttc ctgataaacg tggtctcgca
     6481 acaggtttag cgattatggg gtttggtttt gcttct
//
LOCUS       DAVHSL010000083         6337 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000083 DAVHSL010000000
VERSION     DAVHSL010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6337
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.085"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..306
                     /locus_tag="VVR39_002061"
                     /pseudo
     CDS             1..306
                     /locus_tag="VVR39_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            473..673
                     /locus_tag="VVR39_002062"
     CDS             473..673
                     /locus_tag="VVR39_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031459.1"
                     /translation="MVVSASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            698..1114
                     /locus_tag="VVR39_002063"
     CDS             698..1114
                     /locus_tag="VVR39_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031460.1"
                     /translation="MKTALDSLKDVIANASDSKPTQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1345..2052
                     /gene="ccdA2"
                     /locus_tag="VVR39_002064"
     CDS             1345..2052
                     /gene="ccdA2"
                     /locus_tag="VVR39_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6031461.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2063..2620
                     /gene="sdbB"
                     /locus_tag="VVR39_002065"
     CDS             2063..2620
                     /gene="sdbB"
                     /locus_tag="VVR39_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU6031462.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2994..4385
                     /locus_tag="VVR39_002066"
     CDS             2994..4385
                     /locus_tag="VVR39_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU6031463.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNVNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4528..5445
                     /gene="adcAII"
                     /locus_tag="VVR39_002067"
     CDS             4528..5445
                     /gene="adcAII"
                     /locus_tag="VVR39_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU6031464.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5453..>6337
                     /gene="phtD"
                     /locus_tag="VVR39_002068"
     CDS             5453..>6337
                     /gene="phtD"
                     /locus_tag="VVR39_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU6031465.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGL"
BASE COUNT         1944 a         1128 c         1345 g         1920 t
ORIGIN      
        1 ccagaaaaag tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt
       61 tagattgatg aaacaggatt tgatacttat ttttatcgag aatatggtcg ctcattaaaa
      121 ggtcagttaa gaagaggcaa agtatctgga agaagatatc agaggatttc tttggttgca
      181 ggtctaacaa atggtgaatt aatcgctcca atgacttacg aagagacgat gacgagcgac
      241 ttttttgaag tatggtttca gaaatttctc ttaccaacat taaccacacc atcggttatt
      301 atagtaaaat ggaataagaa caggacaaat cgatcaggac aatcaaatca atttctagca
      361 atgttttaga agtccatatg tactattcta gtttcaatat accataactg ctcctagtca
      421 acctgcaagt cctgtcccag ctccaagctc agctccgact caagatccta gagtggtagt
      481 aagcgcttcg gctagctcaa cgagcacaca agctcaagag caagttgaca agtctgaact
      541 tcgtgccttg agtcaagagt tagaccaacg cttgaaagct ttggcaacag tatctgatcc
      601 gaaaatcgat gcaaccaagg ctgtcctcct agatgctcaa aaagctccgg aagatagtgc
      661 cttgacagag taaggtctgc atactgcagt agagtctgtg aagactgcct tggactctct
      721 caaagatgtg atagcaaatg ctagcgacag caagcctaca caggacaaga aggatgcaaa
      781 acaaggaacg gaagatagta aggattcaga taagatgact gaaacaaact cagttccagc
      841 aggagtgatt gtggtcagtc tacttgccct cctaggcgtg attgccttct ggctgattcg
      901 ccgtaagaaa gagtcagaaa tccagcaatt aagcacggaa ttaatcaagg ttctaggaca
      961 gctagatgca gaaaaagcgg ataaaaaagt ccttgccaaa gcccaaaacc ttctccaaga
     1021 aacccttgat ttcgtgaaag aagaaaatgg ctcagcagag acagaaacta aactagtaga
     1081 ggagcttaaa gcaatccttg acaaactcaa gtaaaacatg atttatgaaa tgtcagactt
     1141 aaaagacatt ttcgttcaca aaagcagcga cgagtaatcc ttgtcgttgc tttttggcta
     1201 ttttggggga taagatccgc cttgactagc aaaagaaaag attggtccaa tagtgcccga
     1261 tacgattttg cgtagcagaa agcttacaaa taaaattgaa tatagtaaaa taggattaga
     1321 attattaaga aagttggttc tttattggaa acgatagtat ttttaatctc tgtttttcta
     1381 gcaggtgttt tatccttttt ttctccttgt atttttcctc ttctgccagt ctatgctggg
     1441 attttattgg atgatcaaga aagtgcaaaa agcttttctt tgtttgggag aaaggttctc
     1501 tggtcaggct tgattcgaac actttgcttt atcgctggta tctctctcat tttctttatt
     1561 ctaggctttg gtgctggtta ctttggtcat attctctatg caaattggtt tcgatatggc
     1621 atgggagcta ttattatcat tttgggtctt caccagatgg aaatttttca tttgaagaaa
     1681 ttagaagttc aaaaaagttt tacctttaaa aaatcagatt ctaatcgtta ttggtcagct
     1741 tttttacttg gtattacctt tagctttggt tggacacctt gtattggtcc agttttaagt
     1801 tctgttttag cacttgcggc ttctggaggc aatggcgctt ggcaaggagc gatttatact
     1861 ctcatttaca ctctgggcat ggcccttcct ttcttggtat tggcactagc ttcaggtcta
     1921 gtcatgccat attttagtaa aatcaagcgt catatgatgc tactaaagaa aattggtggt
     1981 ttcctcattg ttttaatggg aattttgtta ctattaggac aagtaaatgt tctagctgga
     2041 atttttgaat aaaggaggac aaatgaaaaa agtaatgttt gctggcttaa gtctcttgtc
     2101 attagttgta ttgatggcct gtggtgagga agaaactaaa aagactcaag cagcacaaca
     2161 gccaaaacaa caaacgactg tacaacaaat tgctgttgga aaagatgctc cagactttac
     2221 attgcaatcc atggatggca aagaagttaa gttatctgat tttaagggta aaaaggttta
     2281 cttgaagttt tgggcttcat ggtgtggtcc atgcaagaaa agtatgccag agttgatgga
     2341 actagcggcg aaaccagatc gtgatttcga aattcttact gtcattgcac caggaattca
     2401 aggtgaaaaa actgttgagc aattcccaca atggttccag gaacaaggat ataaggatat
     2461 cccagttctt tatgatacca aagcaaccac cttccaagct tatcaaattc gaagcattcc
     2521 tacagaatat ttaattgata gccaaggaaa gattggaaag attcaatttg gtgctatcag
     2581 taatgcggat gcagaagcag catttaaaga aatgaactag aatcgataaa atctgattac
     2641 aagatgtagt cagattttgg taacttctaa aactaacttc cagtttccca caacctagct
     2701 tttagtatga gaaaaacgcg tgacatcagt ggaaatccgt cttagattaa cttccactgg
     2761 ttttcttttt cttgatatat aagggttcaa aagcgaaaag actcagaaaa agtgcacgac
     2821 aaatagccct aaaacagagt cgtctgagac taacttccag ttttgggaga gagatggaag
     2881 ttactttgag aagttacggt agtcagattt ttttagaaaa atattttata aatattcaca
     2941 tatctcctat atttatggta aaatagaatc atcagtttat tttggagtca aagatgaata
     3001 tatttagaac aaagaatgtt agtttagata aaacagagat gcataggcat ttgaagttat
     3061 gggatttgat tttgctgggt attggagcca tggtagggac aggtgttttt acaatcacag
     3121 gtactgcagc tgctacactt gctggtccag cactagtgat ttcaatcgtt atttctgcct
     3181 tgtgtgtggg attatcagcc ctcttttttg cagaatttgc ctcgcgagta cccgctacag
     3241 gaggtgccta tagttacctc tatgctatct taggagaatt ccctgcctgg ttggctggtt
     3301 ggttaaccat gatggagttc atgacagcca tatcaggcgt agcttcgggt tgggcagctt
     3361 attttaaagg cttgctctct caatacggga tagcccttcc tcaggcttta aatggtacct
     3421 ttaatcctca agcagggaca tttgttgatt tattgcctat tcttgtcttg gtcttggtga
     3481 cttcgcttgt tttactaaat gccaaggcag ccttacgctt taattcgatt ctagttattt
     3541 tgaaattttc cgctttagct ctctttgttt tagtaggaat ttggaatatt aagtttgata
     3601 attggagcaa ttttgctcct tacggttttg gacaaatcta tggagctagt actggtatta
     3661 tggctggtgc gtccttgatg ttcttcggtt ttttgggatt tgaatccatc tctatggctg
     3721 tagatgaagt caagactcct caaaaaaata ttcctagagg gattgtctta tcgctttcta
     3781 tcgtaaccat tctctatgcc ttggtgaccc ttgttttgac tggtgtggtt cactatagtc
     3841 atttaaatgt cgatgatgcc gttgcctttg cccttcgtag tgttgggatt agttgggcag
     3901 ccaactatgt gtcattagtg gctatcttga ccttgattac agtttgtatt tcgatgacct
     3961 atgccctatc gcgtatgatt tacagtttag cacgtgacgg cttagtgcct gctgccttta
     4021 aggaactgac gaagactagc aaggtaccaa agaatgctac tatcttgaca ggtctagctt
     4081 cagcagtagc agcaggaatg ttcccactag ccagtattgc agccttttta aatatttgta
     4141 ccttagccta cttgatcctg ctggcttatg gtctgattcg cttacggaaa gaaaaaggaa
     4201 tgcccaaagc tggggaattt aaaacaccat tggtacctct gttaccaatt ttatcgatca
     4261 tcatttgttt atccttcatg ttacagtata atgtgaacac ctggattgct ttcctagttg
     4321 cgttgttagt aggaagtatt atttacttca cttatggcta taagcattct accatagaag
     4381 aataaagtga aagtctattg agttgttgac actcagcaga tttttatatg tgaaagaaat
     4441 ttcaaatttt ttctaaaaat atcttgacag attaaatttt caggagtaga atatttacta
     4501 gttaattaaa tggttaagga gttgttcatg aagaaacaaa atttattttt agtcctgtta
     4561 agtgtctttc ttttatgctt gggggcttgt ggtcaaaagg aaagtcagac aggaaagggg
     4621 atgaaaattg tgaccagttt ttatcctatc tatgctatgg ttaaggaagt atctggtgac
     4681 ttgaatgatg ttcggatgat tcagtcaagt agtgggattc actcttttga accttcggca
     4741 aatgacatcg cggccatcta tgatgcagat gtctttgttt accattctca tacgctagaa
     4801 tcttgggcag gaagtttaga tcccaatcta aaaaaatcca aagtgaaggt cttagaggct
     4861 tctgagggaa tgaccttgga acgtgtccct ggactagagg atgtggaagc aggggatgga
     4921 gttgatgaaa aaacgctcta tgaccctcac acatggctag atcctgaaaa agctggagaa
     4981 gaagcccaaa ttatcgctga taaactttca gaggtggata gtgagcataa agagacttat
     5041 caaaaaaatg cgcaagcctt tatcaaaaaa gctcaggaat tgactaagaa attccaacca
     5101 aaatttgaaa aagcgactca gaaaacattt gtaacacaac atacagcctt ttcttatcta
     5161 gcgaagagat ttgggcttaa tcaacttggt attgcaggca tctctcctga acaagaacca
     5221 agtccacgac aattaacaga aattcaggaa tttgttaaaa cctataaggt taaaacgatt
     5281 tttacagaaa gtaatgcttc ttcaaaagta gctgaaactc ttgtcaaatc aacaggtgtg
     5341 ggtcttaaaa ctctgaatcc tttagaggca gacccacaaa atgacaagac ctatttagaa
     5401 aatctggaag aaaatatgag tgttctagca gaagaattaa agtgaggaaa gaatgaaaat
     5461 caataaaaaa tatctagcag gttcagtggc agtccttgcc ctaagtgttt gttcctatga
     5521 acttggtcgt caccaagctg gtcaggttaa gaaagagtct aatcgagttt cttatataga
     5581 tggtgatcag gctggtcaaa aggcagaaaa tttgacacca gatgaagtca gtaagagaga
     5641 ggggatcaac gccgaacaaa ttgttatcaa gattacggat caaggttatg tgacctctca
     5701 tggagaccat tatcattact ataatggcaa ggttccttat gatgccatca tcagtgaaga
     5761 acttctcatg aaagatccga attatcagtt gaaggattca gacattgtca atgaaatcaa
     5821 gggtggctat gtgattaagg tagacggaaa atactatgtt taccttaaag atgcggccca
     5881 tgcggacaat attcggacaa aagaagagat taaacgtcag aagcaggaac gcagtcataa
     5941 tcataactca agagcagata atgctgttgc tgcagccaga gcccaaggac gttatacaac
     6001 ggatgatggg tatatcttca atgcatctga tatcattgag gacacgggtg atgcttatat
     6061 cgttcctcac ggcgaccatt accattacat tcctaagaat gagttatcag ctagcgagtt
     6121 agctgctgca gaagcctatt ggaatgggaa gcagggatct cgtccttctt caagttctag
     6181 ttataatgca aatacagctc aaccaagatt gtcagagaac cacaatctga ctgtcactcc
     6241 aacttatcat caaaatcaag gggaaaacat ttcaagcctt ttacgtgaat tgtatgctaa
     6301 acccttatca gaacgccatg tggaatctga tggcctt
//
LOCUS       DAVHSL010000084         6328 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000084 DAVHSL010000000
VERSION     DAVHSL010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.086"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            153..467
                     /locus_tag="VVR39_002069"
                     /pseudo
     CDS             153..467
                     /locus_tag="VVR39_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            644..1303
                     /locus_tag="VVR39_002070"
     CDS             644..1303
                     /locus_tag="VVR39_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU6031466.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPIITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1328..2395
                     /locus_tag="VVR39_002071"
     CDS             1328..2395
                     /locus_tag="VVR39_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6031467.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESTVVKVLDKENAIQYGMIWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2498..3508
                     /locus_tag="VVR39_002072"
     CDS             2498..3508
                     /locus_tag="VVR39_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031468.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3520..5211
                     /locus_tag="VVR39_002073"
     CDS             3520..5211
                     /locus_tag="VVR39_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6031469.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5214..5924
                     /locus_tag="VVR39_002074"
     CDS             5214..5924
                     /locus_tag="VVR39_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU6031470.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6020..>6328
                     /locus_tag="VVR39_002075"
     CDS             6020..>6328
                     /locus_tag="VVR39_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031471.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     I"
BASE COUNT         2113 a          878 c         1199 g         2138 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgcta aactttcaga aaaaagttgg agtatatgat
       61 gctaggtgac tgcgtcatgt tagtaaacga aatggaaata actgatcata gagtagataa
      121 cttatttgaa aaagggaaaa atgagataaa agatccatgt agtagattta gcaataggac
      181 atataaaagc tttagaaaaa gtatctgaaa aaacagatgt ttatatctat aacctaggct
      241 cgggagaagg cactagtgta ttacaacttg taaatacatt tgaaagtgtt aataagatcc
      301 ctattcctta taaaatagtt ccaagacgtt caggagacgt tgcaacttgt tatgcaaatg
      361 cagacaaagc atataaggaa ttaaattgga ggacaacaaa atcgattgaa gacatgtgta
      421 gagatacatg gaattggcaa tcaaaaaatc ccaatgacta taattgatga tactgtctat
      481 atgagtgctg tattttggaa aaattactta accttttaat gaaatgcata tttaatgaaa
      541 gataaataaa aaaagtttga cagcgcttga caaaggaaac ggtttcattg tataatgtaa
      601 acatggtgac accgatgtca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa
      661 aattaagttc aaagaaaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa
      721 tctttatact aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga
      781 attaccattt atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat
      841 tgaattgttg tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga
      901 tacaccttta caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt
      961 ggatgaagaa attcatatgc gtataactga aatgggaaaa caaaacatac tagttgaacc
     1021 tgcagatgaa gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc
     1081 aggtgtttgt ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg
     1141 gattcctcta accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga
     1201 aattttatta gagaagattc caattattac tgtaaaccgt attgactata ctgtatttga
     1261 agatatgaga caatttgttc catatcacga aaaatttaaa taaaataata aaaaaggaga
     1321 acttatcatg aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac
     1381 tacacttgct gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa
     1441 agctgataaa agtcaagaat tagtaatcta ttcgaactca gtctcaaatg gtcgtggtga
     1501 ttggttaact gctaaagcaa aagaagctgg ttttaatata aaaatggttg atattgctgg
     1561 cgctcaatta gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt
     1621 tggaattggt gctgttgact caaataaaat tagagatcaa aaattactag tacagtacaa
     1681 gcctaaatgg ttagataaaa ttgatcaatc tttatcagat aaagataatt attataaccc
     1741 agttattgtt caacccttgg tattgattgg agctcctgat gcaaaagaaa tgccaaaaga
     1801 ctggacagag ttagctagta aatataaggg acaatattcc atttatggct taactggtgg
     1861 gactggacgc gccatttacg caagtattct agttcgttat cttgatgaaa aaggtgattt
     1921 aggagtatcg gaaaagggct gggaagttgc aaaagaatac tttgcaaatg cctatacact
     1981 acaaaaaggt gaaagcacag ttgttaaagt attagacaaa gaaaacgcta tccaatacgg
     2041 tatgatctgg ggttctggag cgttagtcgg acaaaaagaa caaaatgttg tttttaaagt
     2101 gatgtctcct gaaattgggg ttccatttgt aactgagcaa acaatgattt tgagtacaag
     2161 taagaagcaa gcattggcta aagaatttat tgattggttt ggtcaatctg aaattcaagt
     2221 agagtacagt aaaaactttg gctctatccc tgccaataaa gatgccctca aagagctacc
     2281 agaagatact aagaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt
     2341 tggaaagcat ttggatgaat gggtagaaaa agctgaatta gaatacgtac aataagaaat
     2401 aagagttatt atttatgtcc aagtctctct attatttcta aatttatgga agaaataaag
     2461 agaggctttt ggtttagtaa tagagggagt tagtgagatg attaaatttg ataatattca
     2521 aattaaatat ggtgattttg ttgcaattga taatctgaat ttagatatac atgaagggga
     2581 attctttaca tttcttgggc cttcaggatg tggtaaatca actactttga gagcattagt
     2641 aggtttttta gatccatcat caggaagtat tgaagttaat ggaacagatg tcactcattt
     2701 ggaacctgaa aagcgtggaa ttggtattgt atttcaatct tatgcgctat ttccaactat
     2761 gactgttttt gataatattg catttggttt aaaagttaag aaggtagctc cagatgttat
     2821 taaagctaaa gtatcagcag tggcagcaaa aattaagatc tctgatcaac agttacagcg
     2881 taatgtatca gaattatctg ggggtcaaca acaaagggta gcattggctc gtgctctggt
     2941 tcttgaacct aaaattcttt gtctagatga accattgtca aaccttgacg caaaattacg
     3001 tgtagatttg agaaaagagt tgaaaagact tcaaaaagag ttaggtatta ctactttata
     3061 tgttactcat gatcaagagg aagccttgac tttatctgat agaattgcag tctttaacaa
     3121 tggatacatc gaacaggtcg gtacaccagt agagatttat cataattctc aaactgaatt
     3181 tgtatgtgat tttattggag atattaatgt tttgaccgat gaaacagtcc acgaagtatt
     3241 attgaaaaat acaagcgttt tcttagagga taaaaaagga tacattcgat tagagaaagt
     3301 tcgattcaat cgtgaaactg aacaagattt tattctaaaa gggacaatta ttgatgttga
     3361 gttttctgga gttacaattc actatacaat aaaagtttct gaaagtcaga ttcttaatgt
     3421 aacaagtatt gatagtcagg ctgctattag atctgtcgga gaaagtgtgg aattatttat
     3481 cacaccatca gacgttctgc aattttaagg aggtgcagta tgcgtcataa attaaattta
     3541 aaagattggc ttattcgttt agggttaatc tggttcttag taacatttat tatttatcca
     3601 aactttgatc tagtagtgaa tgtatttgta aaaggaggag aattttccct tgatgctgta
     3661 catcgtgttc taaaatctca gagggcactt cagagtatta tgaacagttt taagttagca
     3721 ttttcactta ttattacagt taatgtcgta ggtattcttt gtgttctatt tacagagtac
     3781 tttgatatta aaggtgctaa aattttaaaa ttaggttata tgacctcttt aatttatgga
     3841 ggagtggttt tagcgactgg atataaattt gtctatggtc cttatggatt gattacaaaa
     3901 tttttacaaa atgttatccc ttctttagac tctaactggt ttattgggta tggtgcagtc
     3961 ttattcatta tgacattttc aggaactgct aatcatacat tgtttttaac aaatacaatt
     4021 cgaagcgttg actatcacac tattgaggct gctcgaaata tgggagcaaa accatttact
     4081 gttttccgaa aagtagtgtt accaacctta attccaactc tatttgcact tactattatg
     4141 gtttttctta gtggtttatc tgcagtagca gcacccatga ttgttggtgg taaagaattt
     4201 caaactataa atccaatgat tattacattt gcagggatgg ggaattctcg tgatttagct
     4261 gccttacttg caattatttt aggtattgca actacaattt tgcttactat catgaataag
     4321 atagaaaaag gtggaaatta tatttctatc tctaagacta aagcgcctct aaaaaaacaa
     4381 aaaattgcgt ctaagccttg gaatatcatt gctcacattg tagcatatgg attgttcaca
     4441 gttttcatgc ttccactaat ttttatagta ttatactcat ttacagatcc agttgcaatt
     4501 caaacaggta acttaacatt atcaaacttt actttagaaa attatcgctt attctttagt
     4561 aatagtgcgg cattctctcc attcttggtc agctttattt attctattat tgctgcgaca
     4621 acagcaacaa ttctcgcagt tgtatttgct cgtgttgtca gaaaacataa atctcgtttt
     4681 gatttcttat ttgaatatgg tgctctactt ccttggttac taccaagtac acttttagca
     4741 gtaagtttat tatttacttt taatcaacca caatttcttg tcttgaatca gattttggta
     4801 ggtagtttgg taattctact tattgcatat atagttgtaa aaatcccatt ttcttataga
     4861 atggtacgtg ctattttatt tagtgttgat gatgagatgg aagatgcagc aagaagtatg
     4921 ggtgcttcac ctttttatac tatgatgaag gttatcattc catttatttt accggttgtt
     4981 ctctctgtta ttgctttaaa ctttaactct ttattaactg acttcgactt atctgtattc
     5041 ctttaccatc ccctagctca accattaggt attacgattc gatctgcagg tgatgaaaca
     5101 gcaacatcta atgcacaagc tctggtattt gtttatacaa ttgttctgat gattatttct
     5161 ggaacggtat tatacttcac acaaagaccg gggcgtaaag taaggaaata atcatgacag
     5221 ccactagtct tgggttatca aatattgaaa tagttgtcag gattgtttta tcagtagtca
     5281 ttggtagtat aattggttta gagagaggga gcaaatccca gcctgcaggc atccgaactt
     5341 atagtattgt ttgtctagct gcatgtttga ttatgatgac gaatgaatac gtatcttata
     5401 aatttgggac aggagatcct acacgattag gagctcaagt tatatcaggt gtgggttttc
     5461 taggcgctgg aacgattctt attacagata aaaagaaaat tacaggtctg acaactgcag
     5521 caggcatttg ggcttcggca ggaattggat tagctattgg agtaggtttt tatgagggag
     5581 ctcttttagt agccatttct gtttggggtg tgatatccat gttccaacca ctaaaaaaat
     5641 atctgcaaaa tcgttctaaa atgattgaat tgtatatagt agttaaatct acagaagcct
     5701 ataatcgtgt attggtttat tgtgcagaaa atggtatcag aatgaccgat tcaagaacag
     5761 cgtttggaga tgttaattct gacagaattg aatactttga tgttccggac aaaaaaatag
     5821 cgtcatttat tactctggaa ttatcaggta gatttgaaca tcttcgactg atggaagaaa
     5881 ttgctaatat tgtaggtgtt atttatgtcg aagaaattag ctgaaattta gtaaacaaag
     5941 ggacagatgt ttttgtcctt ttgcttttta gatgttttaa tcatctaatt tttgagtaga
     6001 tttttgctca gaggttttta tgaaagatta taaaatcaat tttgatttag gtaaaataga
     6061 atattttgat aataattgtt tgatacaagt atacaaattt atttcttttt atgatatttg
     6121 tgaaatggtg tttgcctttc atttacctcc tgatgagttg ataacaaatg ttatctttaa
     6181 agaaaaaatt aactctatgt taaaatgtta cattgacagg ctattatatg tttttataaa
     6241 tcctacacat tttactgaaa aagttaatct acaattttat ggtagttttt tctcatatga
     6301 atttatttgt cgtgaagttg gaaacatt
//
LOCUS       DAVHSL010000085         6203 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000085 DAVHSL010000000
VERSION     DAVHSL010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.087"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            43..1068
                     /locus_tag="VVR39_002076"
     CDS             43..1068
                     /locus_tag="VVR39_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6031472.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAREISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1058..2065
                     /locus_tag="VVR39_002077"
     CDS             1058..2065
                     /locus_tag="VVR39_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6031473.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSAFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2065..3072
                     /locus_tag="VVR39_002078"
     CDS             2065..3072
                     /locus_tag="VVR39_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6031474.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3072..3866
                     /locus_tag="VVR39_002079"
     CDS             3072..3866
                     /locus_tag="VVR39_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031475.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVMANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            4254..4679
                     /locus_tag="VVR39_002080"
     CDS             4254..4679
                     /locus_tag="VVR39_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6031476.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            4735..5052
                     /locus_tag="VVR39_002081"
     CDS             4735..5052
                     /locus_tag="VVR39_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU6031477.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            5366..>6203
                     /locus_tag="VVR39_002082"
     CDS             5366..>6203
                     /locus_tag="VVR39_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU6031478.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEKVLNKNGK
                     PKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVDHRSFKRQNSDYLPTIH
                     LGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLKGWIGNLLDNLSTAYEK
                     FKD"
BASE COUNT         2439 a          851 c         1054 g         1859 t
ORIGIN      
        1 attatcgata caatagactt gaaatatgtt taaggagttt ttatgaaaaa caaatttttt
       61 ctaatagcta ttttagctat gtgtatagtt tttagcgctt gttcttctaa ttctgttaaa
      121 aatgaagaaa atacttctaa agagcatgcg cctgataaaa tagttttaga tcatgctttc
      181 ggtcaaacta tattagataa aaaacctgaa agagttgcaa ctattgcttg gggaaatcat
      241 gatgtagcat tagctttagg aatagttcct gttggatttt caaaagcaaa ttacggtgta
      301 agtgctgata aaggagtttt accatggaca gaagaaaaaa tcaaagaact aaatggtaaa
      361 gctaacctat ttgacgattt ggatggactt aactttgaag caatatcaaa ttctaaacca
      421 gatgttatct tagcaggtta ttctggtata actaaagaag attatgacac tctatcaaaa
      481 attgctcctg tagcagcata caaatctaaa ccttggcaaa ctttatggag agatatgatt
      541 aaaattgatt caaaagcctt aggtatggaa aaagaaggtg atgagttaat caaaaatact
      601 gaagctcgta tatccaaaga attagaaaaa catccagaaa tcaaaggaaa aatcaaagga
      661 aaaaaagtat tatttactat gattaatgct gcagatacat caaaattctg gatttatact
      721 agcaaagatc caagagcaaa ttatttaaca gatttaggtc tagttttccc tgaatcatta
      781 aaagaatttg agagtgaaga tagttttgca agggaaattt ctgcagaaga agcaaataag
      841 ataaatgatg ctgatgtaat cataacttat ggtgatgata aaactcttga agctttacaa
      901 aaagatcctc ttttaggtaa aataaatgca attaaaaatg gtgccgttgc tgtaattcca
      961 gataatacac cgttagcagc ctcatgcact ccaacaccac tttcaataaa ctatactatt
     1021 gaagaatacc taaatctttt aggaaatgca tgcaaaaatg cgaaataaaa aacaaataaa
     1081 cctaggcata atttttgtaa tctgcctagg tcttcttatt acaatatttt tgtcattaaa
     1141 gcttggaaca aaagaaatta atatcagaga ttttttagca gcttttggaa tgggtaatac
     1201 aaatgatgat tttattaaat caattatata taaaagaata cctagaacta tttttgcaat
     1261 tttagcaggt tctagtcttg ccataagcgg tgtattgatg caatcagtta ctagaaaccc
     1321 aatagctgat ccaggtatac tcggtataaa cacaggagca agtcttagtg tagtaattgg
     1381 tctttctttt ttaggaattt catcaagcat aagccatata agttttgcaa tcattggtgg
     1441 cttagtaagt gcaatttttg tatacgcgat tgctgtaagc ggaaaagcag gccttacccc
     1501 tataaaactt gccttatcag gaacttgtgt tagtatggct ttaagcagtt ttgtaagttt
     1561 tttaatttta ccgaataata acgtcttaga caaatttaga ttttggcaaa taggtagcct
     1621 tggagcagct acattatctt ctatatctac actactacct tttataattt taggtcactt
     1681 gatagctata tttatttcat cagatttaaa cgctttagct atgggtgatg aaatggctgt
     1741 tggtcttgga gttaatgtta ataggataag atcacttgca ataattgcaa gtgtgctttt
     1801 atgttcaagt attactgcaa ttggtggacc tattggcttc gtaggtctta tagttcctca
     1861 cttttgtggc ttatttataa gcaaagatat acgcacaatg accatttctt cagcttttat
     1921 aggtgcagag ctcttgctta tatgtgatat aatcggccgt atgttaggta aaccaggtga
     1981 aattgaagtg gggataatta ctgcaataat cgggggtcca gtacttattt atgtaactat
     2041 gaaaaataga ggggttaata actaatgcaa aatttaatta taggtattca aaaaagaaaa
     2101 aatagaataa cactattttc ctcactattt ttattaataa taatcagtct atcatttttc
     2161 attttactta tcggagatga aagttattct ttttcaactt tgattaaagt cttaaatagt
     2221 gaaactgttc ctggagctag tttttcgatt atggaaatta gattaccaaa attattagca
     2281 ggaattatag ctggctggtc ttttggattg gcaggattta tctttcaaac tatgttaaga
     2341 aatcctcttg caagtcctga tataatcggt gtcacaagtt cttcatctat tgcagcggtc
     2401 ttttgcatat tggtattaaa aacaaatagt ttaactactg gaattatttc aataacttgt
     2461 ggactaacat catctttaat attattttta ctagctaaaa aagatggttt ttcagcagca
     2521 agactgataa tattaggtat tggttttcaa gctgtcacaa gagcaggcac ctcattttta
     2581 ttgttgaaag tagcaagata tgaattacaa gaagttatga gatggctcag tggctcttta
     2641 tcttttacaa agttagatga catacctctt gttctaatag taagtattat tgctactata
     2701 ttagttttat tttttaataa aagactagaa attattgaac ttggtgaaga aatagcaatc
     2761 ggacttggag caaatcccga gctttcaagg cttgttttaa ttttttgcgc tgtatcttta
     2821 actgcttttt ctacttcaat tacaggacca atagcttgta tatctttttt agctggtccc
     2881 atagccttaa atattggcaa gaaaagaagc ccaatattag ctggattggt tggaatttta
     2941 ctagttttgt tatcagacat attctctcaa aatattttac cagctagata tccagtaggt
     3001 gttgtaactg gcttgttagg ttcaccatac ttaatatact tactaataaa aatgaacagg
     3061 agaaatatat aatgaaaggt ctgtggtcaa ataatcttac ctgcggttat gatgaaaaaa
     3121 taatcttgga aaatataaat ataaaaatac ctgaagaaaa aatatcagtt attattgggt
     3181 caaatggttg tgggaaatca acactcatta aaaccttgtc tcgacttata aagccattag
     3241 agggagaagt attgcttgat aataaatcaa ttaattctta taaagaaaaa gatttagcaa
     3301 aacacatagc tatattacct caatctccaa taatccctga atcaataaca gtagctgatc
     3361 ttgtaagccg tggtcgtttc ccctacagaa agccttttaa gagtcttgga aaagatgacc
     3421 ttgaaataat aaacagatca atggttatgg ccaatgttga agatctagca aataacctag
     3481 ttgaagaact ttctgggggt caaaggcaaa gagtatggat agctctagcc ctagcccaag
     3541 atacaagtat cctactttta gatgagccaa ctacttactt ggatatctca tatcaaatag
     3601 aactattaga cctcttgact gatctaaacc aaaaatataa gacaaccatt tgcatgattt
     3661 tgcacgatat aaatctaaca gcaagatacg ctgattacct atttgcaatt aaagaaggta
     3721 aacttgttgc agagggaaag cctgaagata tactaaatga taaactagtt aaagatatct
     3781 ttaatcttga agcaaaaatt atacgtgacc ctatttccaa ttcgcctcta atgattccta
     3841 ttggcaagca ccatgttagc tcttaataat tgaatattgg aattcattta aaagtcgcaa
     3901 attttgaact gaccctcaaa agttaggcca aaaaactaac taaaggaggt cagtttttta
     3961 atggcaaata cagcacagaa tttaagataa aattagtaaa agaatatcat gaatgaaaaa
     4021 taggatatag agaataacag caatattaaa aagatcagga ctgataataa acaaaaagaa
     4081 agtacaacga ctagttcaaa agctaaaact tcaagtaaaa agttattcaa gaaaatctag
     4141 aaaatactca tcctacaaag gacaggtagg aaaaatatcg gacaacaaaa taaaaagaaa
     4201 tatttattac cgaaaaaaag gggaaatcga gtcaagtacc aacaggctca tctattccaa
     4261 aaagatattt actcgatgga aaaactccta gaattagtgc tacaaatatt gacaatggta
     4321 tcttaggtta ctacgaagat atagatgata aaaattatag agtttttgaa aattttatat
     4381 ctgtttcatt tttaggagca gtcttttatc ataaatataa agcaagccta gatatgaaaa
     4441 ttcattgttt aaaattaaaa aataaagaat tgaataaaga agtagcattc tatttaactt
     4501 caattattag gcaagcttta aaaaatactg aatataaaga tcaaatatct agcacagtat
     4561 tgccagatat caaaattaaa ttaccgatag acagtagagg tactccagat tggaattaca
     4621 tggaaagata tatagaagac ttaaaattaa aatgcaatat agcaaattat aatatttaaa
     4681 acaagaacga ttagaaataa aaatctagtc gttttttatt ttaagaaagg atacatgatg
     4741 gcaagtaaaa gattaagtat tgaagaacag attgaaaaga aagaagaaag cattaagcaa
     4801 ttacaaaatc aaaaaagaca gttgaagaaa aaacttaatg aacaagaaag aaaagcaaga
     4861 aacaaaagac ttatagaaaa aggtgcagtg tttgaaagta tttttgaaga aagtattgat
     4921 ttaacaaaag atgaatttta taagttaata aaaacgttaa atgatgaaga aataagatta
     4981 aacataatgg aaattttaga agaaagaata gatgataatg tagaaaaatc atctaaagat
     5041 gaaataacat aattgtccct tggttacaag ggcgcaatta tacaccctaa agggtgcttg
     5101 cgtcctgcgg agtcaaaccc ttgcagggag caacaaccat tcgcttttta aaagtcaagg
     5161 gtaaataaac tcgctaaggc tcgcccttga cttttaaaat ttgaaatgaa agtaacaatt
     5221 aagccgacat actgaaacaa caaaaattaa ttcagtagtc ggctttttta attctatcat
     5281 ttcaaaacgc tcattcacaa agaggatata aaaaaactat taagtctcca cctaaaacaa
     5341 caaagaaaga aaggaagtga taaaaatggc agacagtttt catttttcag taaacataat
     5401 atcaagagga aaaggcaaaa gtgcagtagc aagtgcagca tatataagtg gagaaaaaat
     5461 aaaaaatgaa tgggacggag taacccatga ctacacaaga aaagaaaaaa tattagtaaa
     5521 aaatataata ttgcctgatc atataccaaa agaatttaat gataggtcta ccttatggaa
     5581 taaagtagaa atggcagaaa aaaattctaa tgcacaacta gcaagacaat tcataatagg
     5641 actaccaaaa gagttatctt taagtgaaaa taaaaacctg gttgaaagat atataaaaga
     5701 aaatttaaca tcacaaggaa tgatagtaga ttatgcaatt catgatgaga gtcaagataa
     5761 aaatggaaat atccattgtc atataatgac cataatgcga ccaataaacg aaaaaggaga
     5821 aaaagtatta aacaaaaatg gaaaaccaaa gacaagaaaa gtagaactaa caacctggaa
     5881 cgatacaggc aatgtagaaa aatggagaga aaatttttca gatctttgta acaaatattt
     5941 agaaagagca ggagcagaaa aaagagtaga ccataggagt tttaaaagac aaaattcaga
     6001 ttatctaccg acaatccatt taggatcagc agcaagtgca atggaaagaa agggaataga
     6061 aactgacaag ggaaactata atagagaaat aagaaaatat aatcaacttg taaaaacaat
     6121 aaaagaagag ataaaaacat taaagggttg gataggaaat ttattagata acttatctac
     6181 tgcttatgaa aaatttaaag ata
//
LOCUS       DAVHSL010000086         6101 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000086 DAVHSL010000000
VERSION     DAVHSL010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.088"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            33..863
                     /locus_tag="VVR39_002083"
     CDS             33..863
                     /locus_tag="VVR39_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6031479.1"
                     /translation="MSEKQKISVLMSVYIKENPTFLKDAIESVQNQTLKPSELVLVED
                     GPLTPELYQVLDQVETESEIPVKRYPLEQNQGLGLALRQGVLQCQYNIIARMDTDDIA
                     VPDRFEKQLQLMEKDKLDLLGGHIAEFIDNPDEIVSYRRVPTQHADIVAYQRMRSAFN
                     HMTVMFKKDMVLKAGNYEDGLYMEDDLLWLNMIAAGAKTGNLDQILCQVRVGAGMFER
                     RGGLRYLKLYRQARQRMLKRGQISYMEYAKSVAIQMIVALCPGFVRQFIFMKLLRKSK
                     "
     gene            949..2799
                     /locus_tag="VVR39_002084"
     CDS             949..2799
                     /locus_tag="VVR39_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6031480.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLTFLFYQLMIGFWGLNASISRYSKITDFMKIFFGATASSILS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDAKKKGQRLGGIPVLGSYDNLSELAKRHQIER
                     VIVAIPSLDPLEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIREIQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2976..3053)
                     /locus_tag="VVR39_002085"
                     /pseudo
     CDS             complement(2976..3053)
                     /locus_tag="VVR39_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3103..3735)
                     /locus_tag="VVR39_002086"
     CDS             complement(3103..3735)
                     /locus_tag="VVR39_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEU6031481.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     RDIKFDMLGARETGIQKLPVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(3757..4629)
                     /gene="sdaAA"
                     /locus_tag="VVR39_002087"
     CDS             complement(3757..4629)
                     /gene="sdaAA"
                     /locus_tag="VVR39_002087"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU6031482.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(4638..5309)
                     /gene="sdaAB"
                     /locus_tag="VVR39_002088"
     CDS             complement(4638..5309)
                     /gene="sdaAB"
                     /locus_tag="VVR39_002088"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU6031483.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKE
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            5551..>6101
                     /locus_tag="VVR39_002089"
     CDS             5551..>6101
                     /locus_tag="VVR39_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6031484.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTA"
BASE COUNT         1741 a         1197 c         1372 g         1791 t
ORIGIN      
        1 gtggaaggaa atctatacat tggagaaaaa ctgtgtctga aaagcaaaaa atcagcgtat
       61 tgatgtcggt ctatatcaag gaaaatccga catttttaaa ggatgctatt gagagtgttc
      121 aaaatcagac tctgaaaccg agcgaattgg ttctggttga ggatgggcct ttgacacctg
      181 agctctatca ggtgttagac caggtggaga ctgagtctga aattccagtg aaacgctatc
      241 ctcttgagca gaatcaaggt ttgggtctgg ctcttcgaca gggtgttttg cagtgtcagt
      301 acaatatcat cgctcgtatg gatacggatg atatagctgt tccagaccgt tttgagaaac
      361 agcttcagtt aatggagaag gacaagcttg acctattagg tggacatatt gcagaattta
      421 ttgataatcc tgatgagatt gtttcttacc gtcgtgttcc gactcaacat gcagatattg
      481 tagcttatca aaggatgaga agtgccttta accacatgac tgtcatgttc aagaaggaca
      541 tggttctcaa ggcaggcaac tatgaggatg gcctttatat ggaagatgac ctcctctggc
      601 tcaatatgat tgctgcagga gccaagactg gaaatctgga tcaaatcttg tgtcaggttc
      661 gtgtcggagc agggatgttt gagcgtcgtg ggggactgcg ttacctcaaa ctctatcgtc
      721 aggctcgtca gcgcatgctg aagagagggc aaatttctta catggagtat gccaagagtg
      781 ttgccattca gatgattgtt gccctttgtc caggatttgt cagacagttt atttttatga
      841 aactgttacg aaaaagcaag taaaagattg tagcaaatcg taaactggat aaaaagtgtt
      901 ataataacaa tataactatc cagttctttt aaggaggagt aaatttctat gaataaaaaa
      961 ctcacagatt atgtgattga tctggtggaa attttaaata aacaacaaaa gcaggttttc
     1021 tggggaatat ttgatatttt cagtatggtg gtttccatca ttgtatctta tattttattt
     1081 tatgggctga ttaatccagc acctgttgac tacattatct atacgagttt gaccttcctg
     1141 ttctatcaat tgatgattgg tttttggggc ttgaacgcga gtattagtcg ttacagcaag
     1201 attacggatt tcatgaaaat cttttttggt gcgactgcca gcagtatcct gtcatatagt
     1261 atctgctatg ccttcttgcc actcttctcc atccgtttca tcattctctt tatcttgttg
     1321 agtaccttct tgattttatt gccacggatt acttggcagt taatctactc cagacgcaaa
     1381 aaaggtagtg gtgatggaga acaccgtcgt accttcttga ttggtgctgg tgatggtggg
     1441 gctctcttta tggatagcta ccaacatcca actagtgaat tggaacttgt tggtattttg
     1501 gataaggatg ctaagaaaaa gggtcaaaga cttggtggta tccctgtttt aggctcttat
     1561 gacaatctgt ctgaattagc caaacgccat caaatcgagc gtgtcatcgt tgcgattccg
     1621 tcgctggatc cgttagaata tgagcgtatc ttgcagatgt gtaataagct gggtgtcaaa
     1681 tgttacaaga tgcctaaggt tgaaactgtt gttcagggcc ttcaccaagc aggtactggc
     1741 ttccaaaaaa ttgatattac ggaccttttg ggtcgtcagg aaatccgtct tgacgaatcg
     1801 cgtctgggtg cagaactgac aggtaagacc atcttagtca caggagctgg aggttcaatc
     1861 ggttctgaaa tctgtcgtca agttagtcgc ttcaatcctg aacgcattgt cttgctcggt
     1921 catggggaaa actcaatcta ccttgtttat catgaattaa ttcgtgagat ccaagggatt
     1981 gattatgtac ctgtgattgc ggacattcaa gactatgatc gtttgttgca agtctttgag
     2041 cagtacaaac ctgctattgt ttatcatgcg gcagcccaca agcatgttcc tatgatggag
     2101 cgcaatccaa aagaagcctt caaaaacaat atccgtggaa cttacaatgt tgctaaggct
     2161 gttgatgaag ctaaagtgtc taagatggtt atgatttcga cagataaggc agttaatcca
     2221 ccaaatgtta tgggagcaac caagcgcgtg gcggagttga ttgtcactgg ctttaaccaa
     2281 cgtagccaat caacctactg tgcagttcgt tttgggaatg ttcttggtag ccgtggtagt
     2341 gtcattccag tctttgaacg tcagattgct gaaggtgggc ctgtaacggt gacagacttc
     2401 cgcatgaccc gttactttat gaccattcca gaagctagcc gtctggttat ccatgctggt
     2461 gcttatgcca aagatgggga agtctttatc cttgatatgg gcaaaccagt caagatttat
     2521 gacttggcca agaagatggt gcttctaagt ggccacactg aaagtgaaat tccaatcgtt
     2581 gaagttggaa tccgcccagg tgaaaaactc tacgaagaac tcttggtatc aaccgaactc
     2641 gttgacaatc aagttatgga taagattttc gttggtaagg ttaatgtcat gcctttagaa
     2701 tccatcaatc aaaagattgg agagttccgc actctcagtg gagatgaatt gaagcaagct
     2761 attatcgcct ttgctaatca aacaacccac attgaataaa aaagaaaaac gcatattatc
     2821 aagttaacaa ccttggtaat atgcgtttta ttatgtagag acttatactc tttgaaaatc
     2881 tcttcaaacc acgtcaacgt cgccttgccg taggtatggt tactgacttc gtcagttcta
     2941 gccacaacct caaaacagtg ttttgatctg acttcgtcag ttctatctgc aacctcaaaa
     3001 cagtgttttg agcagcccgc agctagtttc ctagtttgct ctttgatttt cattgagtat
     3061 tacttcattt tcttctgaaa tggaattgtt acccagtcta tgctattgaa aatacgccaa
     3121 aacttctaag ggtttgtgag cgatataatc aggttgatag tttagtagat ctgcttgctc
     3181 tccaaatccc caagtgacgg gcaatttctg aatacctgtt tctcgagctc ccagcatatc
     3241 aaacttgata tctctgatga tgatggcttg ttctggtgct agttgatgtg tctgcagggc
     3301 ttggtgaatg acatctgcct tatggggtgc ttcagggcta gaaccataaa tgccatcaaa
     3361 gaaatgatgg atttccaagt tttttgccat gtcttgagca gtagatgtat tctttgtcgt
     3421 ggtgatgtag agtggataac tgcttgataa ctcctcaagc aagtctataa tctgaggaaa
     3481 gagttgagct tcatagatgc cttttgcctt atagtaagaa cgatatatct gcatggcttc
     3541 agaaatttgg tctttggaca ggcaggtcgc aaaactactt tcgagaggtg gtcccataaa
     3601 accacgaata gttttggcat cagggctagg cacccccagc tctttaaagg tataggtaaa
     3661 ggcattgtga atcccgatag aactatcaac gagggttcca tccaaatcga aaaaaatcgc
     3721 tgtgatagag gtcatggttt ctcctatttg ataagcttat tctccgaaaa tttctttttg
     3781 gaggcgacga ccagtagggg tggtagcgag tccaccttca gctgtttcac gaaaggcagt
     3841 tggcatgctt gctcctactt ggtacatggc atcgatcact tcatccacag ggattttaga
     3901 ttcgatacct gccaaggcca tgtctgctgc gatgaaagca aagctagctc ccatggcatt
     3961 acgtttgaca cagggaactt cgaccaaacc tgcaacaggg tcacagatga ggcctagcat
     4021 atttttaatg acaaaggcaa tagcttgact ggcctgataa ggtgttccac ctgcagccag
     4081 agtcaaggcg gcagcactca tagcagaggc tgaaccaact tcagcttgac acccaccctc
     4141 agcacctgag atggaggcat tgtttgcgat gactagtcca aaggcaccag cagcaaagag
     4201 gaaatccaat tgttgctcgt ggctgaggtc taatttttca atagcagcag tgagaacgga
     4261 tggcagacag ccagcacttc cagcggttgg agtggcacag accaagccca ttttggcatt
     4321 gtgttcattg actgcgatgg catttcgggc agccgagaga atcgtataat ctgacagagt
     4381 ttttccgttt tcgatgtagt gatccaattt ggcagcatct ccacctgtca ggccactacg
     4441 agatttattt tcattgaggc caagttggac agaggctttc ataacttcca gattgcgttc
     4501 catgagaagg aagacttctt cacgttcgcg accggtcaat tcaaactctg ttgtaatcat
     4561 gagttctgcg acatttcctt gaaagtccag atctgcttgc tcgaccaatt ctttgataga
     4621 ataaaacatg cttcctccta tttaaagaaa ttgacattgt ggagatgagg gatttttcgg
     4681 atttcttcga tagcctcatc acagttgcga ctgtcaactt cgataatcat aatggctttt
     4741 tcaccagctt tttcacgagt gacattcatc tgggcgatat tgataccata gcgggaaagc
     4801 gcctctgtaa caagggcaat catacctgga atatcttgat gaacgatgat gatagtcggt
     4861 gtattcatat tgagagagac ggcaaaacca ttgagttcgg ttacctgaat atttcctcca
     4921 ccgatagaaa taccagtcac gctgatggtc ttgtgggcat ttttaacagt aattttagtg
     4981 gtgttagggt gaggggcatt gctttctttc tgaatggtcc agacaatctt gataccacgc
     5041 ttgtgggcaa tttccagact atttggaatt tcaggatcat ctgtatccat tcctaaaata
     5101 cctgcaacaa gggctaggtc tgttccgtga ccacgatagg tcttggcaaa tgagttaaaa
     5161 agttggaatt caacttctgt cggagtatca tcaaaaatgg aagagacaat cttcccaata
     5221 cgaacagcac cagcggtatg gctactagat gggccaatca taactggtcc gatgatatca
     5281 aagacagatt gaaaacgaag tgatttcatc agtttcccct tataaaaatt cttatctcta
     5341 ttatatcaaa gaatgagggg cttggcttta attgtggatg aaaacctttc taatacctca
     5401 aatagcataa aaatagtatc ttttatgaca aaaaacacct tatttaggga aataaaaaat
     5461 aattttgtaa tatttctaca taaaagtgtc aagaaacggt aatatttaaa gggtatgata
     5521 gaactataga aagaaggaga attttcgaat atgaaatcaa taactaaaaa gattaaagca
     5581 actcttgcag gagttgctgc cttgtttgca gtatttgctc catcatttgt atctgctcaa
     5641 gaatcatcaa cttacactgt taaagaaggt gatacacttt cagaaatcgc tgaaactcac
     5701 aacacaacag ttgaaaaatt ggcagaaaac aaccacattg ataacattca tttgatttat
     5761 gttgatcaag agttggttat cgatggccct gtagcgcctg ttgcaacacc agcgccagct
     5821 acttatgcgg caccagccgc tcaagatgaa actgtttcag ctccagtagc agaaactcca
     5881 gtagtaagtg aaacagttgt ttcaactgta agcggatctg aagcagaagc caaagaatgg
     5941 atcgctcaaa aagaatcagg tggtagctat acagctacaa atggacgtta tatcggacgt
     6001 taccaattaa cagattcata cctgaacggt gactactcag ctgaaaacca agaacgtgta
     6061 gcagatgcct acgttgcagg acgttacggt tcatggactg c
//
LOCUS       DAVHSL010000087         5886 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000087 DAVHSL010000000
VERSION     DAVHSL010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.089"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            271..591
                     /locus_tag="VVR39_002090"
     CDS             271..591
                     /locus_tag="VVR39_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6031485.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETYYQ
                     PKER"
     gene            complement(1094..1474)
                     /locus_tag="VVR39_002091"
     CDS             complement(1094..1474)
                     /locus_tag="VVR39_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEU6031486.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(1620..2972)
                     /locus_tag="VVR39_002092"
     CDS             complement(1620..2972)
                     /locus_tag="VVR39_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEU6031487.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQTLQNELIQLQQQGDSSSLSDTTSDDDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILASNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKVDVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVILQKDMPVEVQIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(2969..3436)
                     /locus_tag="VVR39_002093"
     CDS             complement(2969..3436)
                     /locus_tag="VVR39_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6031488.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(3429..5648)
                     /locus_tag="VVR39_002094"
     CDS             complement(3429..5648)
                     /locus_tag="VVR39_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU6031489.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEDGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
BASE COUNT         1926 a         1177 c          814 g         1969 t
ORIGIN      
        1 gtacctctta ttaagctcat ttcaaaatta cgttaacttt tttcacgaaa aggagaaaat
       61 tatgcgttat gattatggat agcgctttca aatttttaaa ctcctatccc atccttttat
      121 ctatattatg agcgaaaata taataactgt caagtaacta aagtgaattt tataaaaaaa
      181 ttacaagcca aatttgtaaa gtttacacta agccgctagg gcaatcgtct atcagaatgt
      241 ccgtttattt gtcaataatc cgagaaaatc ttgcaacgct tagaagtcta taaaaactat
      301 caacatttat atgacttgcg aatagcaatc ctgctcaacc tttccacact ctatctatac
      361 aatcaagata aaaacatgtg taagcaaatc tgctacactt tactagagga cgccaagaat
      421 aagaaaagct acgataggct ggctatctgc tatgtccgta ttgggatttg tacagacgat
      481 tctaaactta tccaaaaagg gttctccctt ctggagctaa ccgaggaaac ttctatgctg
      541 tctcatctca aaaaagaagt agaaacctat tatcaaccga aggaaagata aaaaagccga
      601 gggatttcct cgactcttta catattattt gttcgttagt tcttaatacc agccattgtt
      661 aaaccagaag tttttagctc tgccaagcca catagtgtgt ttactactat gtgtccatgt
      721 caccatgaat cgccgaacga tttaacgaga aagtatgact tttacgttta tcccaactca
      781 attatgacat ttttttcaaa agtcaatata tctcactttt tcaacgacaa gaaagaggct
      841 gataatctac caacctcttg tttttaaata catttcaagt ccaaactatt ctttatagaa
      901 aaaagtccta taaattcgag caatagttaa aatacaaaca aatataattc ccaaaataga
      961 taacactatt ttcacaaaat tcatttcaga acctattata tatacgtgaa aaaaaggggc
     1021 tattcctaca catatataca ataaataact tacaaagttt atttcaccaa ttcctgcaaa
     1081 aaaatgtttc attttaagca aaaatataac catctaagct accgtcagcc caatcagccc
     1141 catatgcgat tgctccacct agtgaaaatc cagtaacagt tagtgcaacg tttagtgcag
     1201 tattgactaa atggccagct gcactaccta catgtttaat tattaaacta cgtaatgttc
     1261 tcgtaatagc ccctctatta gctgagatag ctttttttat cgcataagca gaataaattg
     1321 ttgcaccacc actatagatg gccaaaccta catccagaac tgttgcaaaa ctacctctac
     1381 tattccacca gttacgacca acaccacccc catcaagata catcatctct tcttgctcaa
     1441 gagcaacata attatttggt aatacgagtt ccatttattt tctccttttt tattaagcat
     1501 ggttaggata gtttcctaac aagtgagcat cgactttgtt tatagcactt agttacctag
     1561 ataagatatc ttccctttat cttactttat tttataggtg acttaatgtt taaaaccaat
     1621 tattgcttga aacttaacat ttccaaaatc caatcaagat aggtttcttt atcatagaca
     1681 atctgcactt caactggcat atccttttgg agtatgaccg tctcgcttcc atgttttaga
     1741 gttaaggttt ctaattctat catgacttta tagaggctaa tattcccctc tttcgtttct
     1801 tgggaaattg ttcctgaatc aatctgtctg acttgtccct ttagtgttcc atatttttga
     1861 ctatttacac cagtaatagc aacatcaact tttgctcctt ttgagacacg agaaatatca
     1921 ctcgcaagta caaaagcctc tacatagtaa cctttttctt tccctgaaac ttctgctatc
     1981 gtttgcccct gctgaataga cattccttgt ttcaaaggta ccagataatg cagagtacct
     2041 tcatttgacg ctaatatact atgagcttta tcttgacctg ttgccactcc aagattagcc
     2101 tcaagctctg taatactttt attgttgttt gaacgagcag tacctaactc actaattaat
     2161 tgagcataaa tattataagc ctgagaagtt ggatcattat aggtacggtt catatcctta
     2221 atattgcttt gttgactatc aatctcgcta ttcttagaag taatatttgt ttttaatgct
     2281 tcgatttttg ttgttatttc tgatatctta gtttctaact tagctttatc atcatctgat
     2341 gtcgtatctg ataaggagga tgagtctcct tgctgttgaa gttgaatcaa ttcattttgt
     2401 agagtttgca agtcggcatc taactgattt ctttcagctg ttattttatt caacttcgta
     2461 tattcatcct gaatctttga atactgggta ccattattat aattttccga gtttaactga
     2521 gacagatagt attcaacttt cccataatat tcctgttctt caccagaatt agataaatga
     2581 ttgtatttct catttaatga ttgttcaaat ttttgaaaga tagcttcttt tgcacgtaac
     2641 ttctccaatt gtttatttaa agagctcgct tgtaaacctt cttgtccact tgataacgaa
     2701 ataatgacat ctccagcatt taccatatct ccttctgact tatgtaaagt aactaccttc
     2761 cctgaaccaa ttgctgatag gaactctgta cctgttataa ctgaatttcc attcgctttt
     2821 acaatatagt ttttgggtat ataagctgcg ccaaccaatg caccgcttaa gataatagca
     2881 gttgaaataa tgagaataaa cgcaaaagct ggtggtctct tatcaaagaa aatacgagaa
     2941 taacgtaatt ctgatttatt atataatttc ataggcttac aattggtcta aaaatatcta
     3001 ctaccatttt ttcaggagaa gaattaacat aaactgtata gacaatccca tccgtttgaa
     3061 tatcattttc atagacatat agatccaatt tagaatacgc atactgtaga tactctggac
     3121 tgtcttcaaa acgaacatat aaacaatatg gaacagagat agaatcctgt acatcataaa
     3181 tgttactgta ctgttgagca ttatgagctt gaatataaaa ctcaaaatca gtcgttatta
     3241 atccatcatc atgaatagta gtaccacaac tttttacaat taatggacca aaaatttgtg
     3301 cttttaacaa ctgcaaatgt tgatgaaatt tattaatttc ctgatctaca tcttctactt
     3361 ttgtatcatg taacttttta cagataactg actttagtac cagtttttta ttatctttta
     3421 cctctaactt agccataagt aacctcctct gtatctaaca cagcctgtga ctgaatttgt
     3481 tgattcactt gaacgctctg caaaccaacc attctagcat actttccatt tttcgccatt
     3541 agttcttcat gagtcccata ttccacaata gtcccatttt ctaaaaagca tatcttatca
     3601 catcgaagaa ttgtagacag cctgtgggct actacaattg ttgtcttatc cattatttta
     3661 ttaaagatta aatcctgaat aatctgttca ctaaatgaat ctaagttaga ggttgcctca
     3721 tcaaatatat acaaatcagc tttactcagt agtgctcttg caatagccaa tcgttgtttc
     3781 tctccacccg agaaattttg accgtcttct tctacaaagg agccataacg attttgaaga
     3841 cgttgaatcg tatcatgaat accaacaata cgacaaactc tcaccatatc ctcatatgta
     3901 acagaaggat taccaatttt tagattatca ataattgtcc ctgtaaagag ttctatggtc
     3961 tgaggaatgt aggaaatttt cttacgtagt ttaccatagt caagatctga taagtcattt
     4021 tctcctatac gaattttccc ctcactcgga tttataaatc ttaataacaa acgaactagc
     4081 gtactttttc ctgctccgct ttctccaaca aaagctattt tttctccttg tttaattcgc
     4141 aaattaaagt ccttgataac aggagggcgt gaaccatagg caaatgttac atctttaaat
     4201 tcaatgtcat cacataaggt gaagtctcta atactataat ccaaggcaat gtcttcacga
     4261 tctacttcca tcaattcttg aagccgacta accgcaacct gtacctcttg aaaggttaac
     4321 tgcaagccaa ctaaattctg aataggttct gtaaaatatt gacttaatgt ctgaaaaacc
     4381 aagaggtccc caatagtcat ttttccatca atgataaata aggcgcccac tcccataaat
     4441 aataacccac ccatggttga ggtcattgaa gatattgtag attgaatatt ctgcaaaaca
     4501 ccctctttat aaccaatttc taaagtatga acaaattttt cttcaatttt gtttaaacgt
     4561 tgttcctcat catgctgaga cttaatggta tcaatgttac gaatagattc aattaactgt
     4621 gaattaagaa gtccatttgc ttccatttgt tcatgattaa tttttttata aggcttttta
     4681 aaacagtata taagaatgat gttaacaata accataaaaa ctaatatcag aaataaagat
     4741 tgattaatag tccaaaggac aaccgcacta ataactgaca aggtgatatc catgactaat
     4801 gaaatagaga ctgacgtaaa cacattcttt atcgtcatcg catcttgaaa tcttgttaaa
     4861 acatcaccaa ctctacgact tccaaaaaaa ctataaggaa gatgaataat atggtcataa
     4921 tatcccatta aaaccggtat atcaattttt cgagatagaa acaaaagaac gtgctgacga
     4981 aatgcagata gaagagtctg taagaacgac actattccaa atactatcaa aaacatatac
     5041 agactatttt ttaaagcata tggaatcacc tcgtccatga taacttttga aaagagactc
     5101 gataaaatac caatgatact taaaacaaag gaagctaata tgactgtact aatcaatcct
     5161 ttttgattaa aaattaacct tccaaataaa tcaagaagtc cttttccctt tagtttccct
     5221 ctttcaaaat ccgaatttgg aaccataaaa agagtaatac cttgataaat ttctcccagt
     5281 tcgtcacttg acatcttgcg tatgccacta gcagggtctg ctacgtagaa cttactattc
     5341 cttttgatac tatgtagtac cacaaaatga ttttgaccta aatcattctt aacttgaaga
     5401 atcgcaggaa atgttaattt tggagtcaaa tcttccagtg ctactcgaac agcttttact
     5461 gtaaaattca acttattcag acctgaaaca ataccactga cagtcgttcc atacatgtct
     5521 gtaccaataa tttcccgaat cttcatgatt gatagttcct ttttgtaaga taaaagaact
     5581 gttgaaacaa ctgccgcagc acaatctgac tgatcatgtt gcatcgtaca aggatatttt
     5641 tttaacatag aaatactcaa ttctttagaa ttaatctaac ttttctttga tgtcacccaa
     5701 acctcaatca ctgcccagta gttcttgaat cagtttattt tcaatcgtat cattctttgt
     5761 tcttgatatc tttccaagca ttgtagtaca gcagattttt gtccaaggac taagcctcct
     5821 ttaacaactc aagctccctt acattatatc gaccagcccc atggaaagat tatggccaga
     5881 ctaatc
//
LOCUS       DAVHSL010000088         5693 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000088 DAVHSL010000000
VERSION     DAVHSL010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.090"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            210..524
                     /locus_tag="VVR39_002095"
     CDS             210..524
                     /locus_tag="VVR39_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031490.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            534..740
                     /locus_tag="VVR39_002096"
     CDS             534..740
                     /locus_tag="VVR39_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031491.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            740..937
                     /locus_tag="VVR39_002097"
     CDS             740..937
                     /locus_tag="VVR39_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031492.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            940..1674
                     /locus_tag="VVR39_002098"
     CDS             940..1674
                     /locus_tag="VVR39_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU6031493.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1686..2327
                     /locus_tag="VVR39_002099"
     CDS             1686..2327
                     /locus_tag="VVR39_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6031494.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2345..2575
                     /locus_tag="VVR39_002100"
     CDS             2345..2575
                     /locus_tag="VVR39_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031495.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKKSK"
     gene            2611..2691
                     /locus_tag="VVR39_002101"
                     /pseudo
     CDS             2611..2691
                     /locus_tag="VVR39_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2927..4690
                     /gene="aspS"
                     /locus_tag="VVR39_002102"
     CDS             2927..4690
                     /gene="aspS"
                     /locus_tag="VVR39_002102"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU6031496.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRVKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            4668..5609
                     /locus_tag="VVR39_002103"
     CDS             4668..5609
                     /locus_tag="VVR39_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6031497.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSLFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
BASE COUNT         1618 a         1040 c         1263 g         1772 t
ORIGIN      
        1 aaccatacct acggcaaggt gaagctgacg tggtttgaag agattttaga agagtattaa
       61 tgatagataa agtggtcagg aacttactcc tgaccttttt cttttgcaaa atgacaaaaa
      121 tcataaactt tttgacaaat atacttatca aaaagaaaaa gatgtgttac aatgtaagca
      181 agttaagaga aaagaagaaa ggagctatga tgtgggtact aggatttata ctatttctga
      241 ttttctttta ttctaatgat tctaaaaaaa tcaagaaact agagaagaaa atcaaaagac
      301 ttgagcgaaa agagaaagga aacgcagaaa tgtcgagatt attacaagaa atgattggaa
      361 aggaaccaat tataacggga gtgtatattg gcccagataa ctgggaagtt gtggatgttg
      421 atgaggaatg ggtaaagcta cgacgtgtag ataatacggg aaaagaaaaa ttcaagttgc
      481 aacgtattga agatatccaa accgttgaat ttgacggaga gtaggtgtgt aacatgcaac
      541 taaaaaatcg tctaaaagag cttcgagctc gtgatggtct caatcaaacc gacctagcca
      601 aactggcagg ggtttccaga cagaccatta gcctactaga acgggatgag tacaccccat
      661 ccattatcat tgccctgaaa atatctcaaa ttttcaacga aacagtcgaa tcggtatttc
      721 gtttggagga ggacgagtga tgaacaagta taaagtgatt tattatgtag tggtcatagc
      781 tttattagtc agtgtatttc tactgattgg gatggactta agctggttta atccctatca
      841 aagcgaccaa tttgtttggg tctactttgc tctcatccca gtaattgaat ggattgaaaa
      901 gaaatccaaa aatctagcaa gtgaaaaagg agaatgaata tgaaaaagaa acgtagattg
      961 ttatttttga tgtctattgt cttggggggg ttcttgggca tgtttgtagg gatgtttaag
     1021 gcacgtgtcg aatcccacga aattatttta gatgtaaaag ccttgatgcc atggatatca
     1081 gctatttgtt tactgatagg tttcattagt atgtttttga ctttcaattt cttaaagaaa
     1141 agtagaaaat ttcattcctt gtatcaagag gaaatggatg acgatctgaa tgaaacctat
     1201 tatgtgcaaa tgtatcggaa tcttgagttt ggaaccattg cttttaatat tacaggtgta
     1261 gcgattccat tggctatttt tatttcatta agtgaggtga ttatattgca tacaaaccct
     1321 caaacatttt tcctttcttt cttactcttt gtggtattct tagtcgctca aaaatctctt
     1381 tttaaaacca ttgcgattgt tcgtcagttt gatttggaat ttttcgctac accaaaggat
     1441 gtcttgaact atataaattc ttatgatgaa ggggagcgtc aggctaattt ggaacagagt
     1501 tttcgaattt tattccaatt acaccaatat gtcttaccag ccttatatat ttttcttatt
     1561 atcctttctt tcttgacagg agagattcag ttactagctt tcttgcttgt aggagccatc
     1621 catgtttata tcaatgtgat gcagttacct atggtaaaac gttatttcaa ataaaggagt
     1681 tatctatgaa attacttaaa aaccttggct ggattcttct agcccttcta tcctttttat
     1741 ttatctatgg ctttattcag gggctcgcga ctgcgtcgct tgctttaggc gcttcaccct
     1801 atgctgttac tctactctat gtggtcttgg ctggagtata tgtgtacggc atttacaaat
     1861 ggtatcagaa agctcctgtt tatattgaga agagcggctt taaccgattt atttggcttc
     1921 ctgtcttggt ttggttctta tctctggtcg ttcaattctt cttgccagat gatccttcag
     1981 taaatcaaca aatagcgaca gacttgacct tgtctcaacc acttttctca ttctttgctg
     2041 tggttatttt tgctcctttg acggaagaga ttgtttttag agggatgtta gcacgctatc
     2101 tctttcctaa gcaggacaat agtaaacgaa ccctgatttt tcttctggta tctagtcttc
     2161 tatttgcctt gattcatttt ccaggtgatg tgcaacaatt ttttgtctat tttagccttg
     2221 gttttagttt gggtttggct tacattagca gaaaaggtct ggtctacagt atttctcttc
     2281 acgctttgaa taatttagtc ggctttttga tgattctcat gctataatag agtcaggagg
     2341 tcacatgaaa cgagtaattt tagtagcagt gattcaggca gtcgttctat ttttcatcat
     2401 tggagcgcta gcttatgcct tcaaaggcga tttcttctat aactatctag cagttgtctt
     2461 tgctcctatt gcaggtgtac tgcgttttgg gacggcttac ataacggaaa ttgtcttgcc
     2521 tcgaaaggca gccgaaatcg ctgaaaagcg taaagcaggc aaaaaatcaa aataaaagag
     2581 tccggtgaag ttcatcggat ttttgtatta tactcaatga aaatcaaaga gtaaactagg
     2641 aagctagccg caggttgctc aaaacactgt tttgaggttg tggatgaaac tgacgaagtc
     2701 agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa ccatacctac
     2761 ggtaaggcga cgctgacgtg gtttgaagag attttcgaag agtattagcg ctaattttta
     2821 gggctttcac ctgactttta aagactggca aacttttctg atgattttca tgaagagcct
     2881 gcgcttttat ggtaaaatag taacagaata aaagaggaga gaaataatga aacgtagtat
     2941 gtatgctggt cgtgttcgtg aggaacacat cggacaagaa ataaccttga aaggatgggt
     3001 tggccgtcgt cgtgaccttg gtggtttgat ctttatcgat cttcgtgacc gtgaaggaat
     3061 catgcagttg gttatcaacc ctgaaaaagt atctgcagag gttatggcaa cagctgaaag
     3121 ccttcgtagc gaatttgtta ttgaggtgac tggtcaggtc gctgcgcgtg agcaagccaa
     3181 tgataagttg ccaactggtg cggttgagtt aaacgtgaca gctcttattg tgcttaacac
     3241 agctaagaca acaccatttg agattaagga tggcattgag gcaaatgacg atacacgttt
     3301 gcgttaccgt taccttgacc ttcgtcgtcc agaaatgttg gaaaatctta aacttcgtgc
     3361 caaggtgacc cactctatcc gcaactactt ggatgagttg gagtttatcg acgtggagac
     3421 accattcctt tctaagtcaa cgcctgaagg ggcgcgtgat tatttagtgc cgtctcgtgt
     3481 taataagggg catttttacg ctcttcctca aagtccacaa atcacgaaac agctcttgat
     3541 gaatgctggt tttgaccgtt actaccaaat cgttaaatgt ttccgtgacg aagacttgcg
     3601 tggagaccgc cagcctgaat ttactcaggt cgacttggaa acgtccttcc ttactgagca
     3661 agaaatccaa gatattacag aaggcttgat cgcgcgcgtg atgaaggaaa caaaaggcat
     3721 cgaagtaacg ctaccgttcc ctcgtgtgaa atacgatgat gctatggctc tttacggttc
     3781 tgacaagcca gatactcgtt ttgacatgtt gcttcaggac ttgacagaag tggtcaaagg
     3841 tgtagacttt aaagtctttt cagaagcacc tgctgtaaaa gcgattgtgg tcaaaggagc
     3901 tgcggacaac tattcacgta aagacatcga caagatgacg gaagtagcca aacagtatgg
     3961 tgccaaaggt cttgcttggg ttaaggtggt tgatggagaa ttaaacggac cagttgccaa
     4021 gttcttgact ggtatccaag aagaattgac aacagcgctt gctcttgaag ataaggactt
     4081 ggttctcttt gtggcggata cgcttgaagt ggctaatgca acactgggtg cccttcgtgg
     4141 acgtattgct aaagagcttg gcttgattga taatgataag ttcaacttcc tttgggtggt
     4201 tgactggccg atgtttgaat ggtctgaaga agaaggccgc tacatgagcg cccaccatcc
     4261 tttcaccctt ccacaggaag agactgctca cgaattagaa ggtgatttgg ctaaggttcg
     4321 tgccattgct tacgatatcg tcttgaacgg ttatgagctt ggtggtggta gccttcgtat
     4381 caaccaaaaa gaccttcaag aacgcatgtt caaggctctt ggtttctcag ctgaagaagc
     4441 caatgaccag tttggtttcc ttcttgaagc catggactat ggtttcccac cacacggtgg
     4501 tttggctatc gggcttgacc gttttgtcat gttgcttgct ggagaagaaa atatccgtga
     4561 agtcattgcc tttcctaaga acaacaaggc aactgaccca atgacacaag ctccatcaac
     4621 agtcgctctc aaacaactag aggaactcag cttacaagta gaagaagatg aaacaaacaa
     4681 aacgaattaa gcggtggcgc tattatctgc gccgctttgc ttatcagata aaaattttac
     4741 gtgtcttaca aagtatctct cgagaaaagt atgatgagaa gatttcggcc tctctggtct
     4801 atggtttttt atcagcagta gcagttaatt tctttttcca accagggcat gtgtattcga
     4861 gtggtgcaac aggtctggca cagattatct ctgccttgag taatcactgg tttggttttc
     4921 atattccgat ttcgctaagc ttctacgcca ttaacttccc tttgatggtc ttagcttggt
     4981 atcagattgg ccataagttc accgtcttta cctttatcac ggtatctatg agttccttat
     5041 ttatccagtt tgtccctgtg gcaaccttga cggaggatcc cattatcaat tccctttttg
     5101 ggggtgttgt tatgggtttg gggattggtt ttgctcttcg aaacaatatc tccagtggtg
     5161 ggacggatat cgtcagcctg actattcgca agaaaacggg taagaatgtc ggtagtattt
     5221 ctttcttggt aaatggaact atcatgctga tagcaggttt gacctttggt tggaaatacg
     5281 ctctttattc tatgattacc atctttgtct ctagccgtgt gacagacgca gtctttacta
     5341 agcaaaagcg tatgcaggcc atgattgtga caaatcatcc agagaaggta attgaaaaaa
     5401 tccataaaaa attgcaccgc ggagcaacca tgatccacga tgcagaagga acctataatc
     5461 acgagagaaa ggcagtttta atcactgtca ttacacgtgc agagtttaat gaatttaaac
     5521 agattatgac acaagtggat ccaagctcct ttgtctctgt ctcggaaaat gttcatattc
     5581 taggaagatt tgttgagata gataattagt gattaatact cttcgaaaat ctcttcaaac
     5641 cacgtcagcg tcgccttacc gtatatatgt tactgacttc gtcagttcta tct
//
LOCUS       DAVHSL010000089         5660 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000089 DAVHSL010000000
VERSION     DAVHSL010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.091"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            368..1714
                     /gene="gdhA"
                     /locus_tag="VVR39_002104"
     CDS             368..1714
                     /gene="gdhA"
                     /locus_tag="VVR39_002104"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU6031498.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2220..2390)
                     /locus_tag="VVR39_002105"
     CDS             complement(2220..2390)
                     /locus_tag="VVR39_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031499.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2403..3044)
                     /locus_tag="VVR39_002106"
     CDS             complement(2403..3044)
                     /locus_tag="VVR39_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6031500.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIFVMKGGKIVESGNHKYLMELGGEYYSLYTKRK"
     gene            3317..3922
                     /locus_tag="VVR39_002107"
     CDS             3317..3922
                     /locus_tag="VVR39_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031501.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHQDHLVFTIEKVVNTDEKEVN
                     HLIKYAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHTKYQKTQTDFQ
                     QEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKIDVEPVFGQ
                     IKASLGYKRCNLRGKRQVRIDMGLVLMANNLLKYNKRTTQN"
     gene            complement(4072..4266)
                     /locus_tag="VVR39_002108"
                     /pseudo
     CDS             complement(4072..4266)
                     /locus_tag="VVR39_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(4293..5210)
                     /locus_tag="VVR39_002109"
                     /pseudo
     CDS             complement(4293..5210)
                     /locus_tag="VVR39_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
     gene            complement(5242..5649)
                     /locus_tag="VVR39_002110"
     CDS             complement(5242..5649)
                     /locus_tag="VVR39_002110"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6031502.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
BASE COUNT         1792 a         1111 c          965 g         1792 t
ORIGIN      
        1 ttggatttct tctttagtta atttcatatc actattatat aatgattttt gattttagtc
       61 tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat ctaacatatc
      121 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatacc
      181 atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg tttttttatc
      241 tattttcaaa aaaaccaaaa actgaattga aagaattttt agaaaatttc tgttttttct
      301 ttacagtgaa aaaaaattct gctataatgt cttatgtaat aaaatatgac aataaaagga
      361 gaacgatatg acatctgcta aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg
      421 taacgggcac gaggctgaat tcctccaagc tgttgaagaa tttttcaaca ctttggaacc
      481 tgtatttgaa aaacaccctg agtatatcga agaaaatatc ttggcacgta ttactgagcc
      541 tgagcgcgtg gtttctttcc gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa
      601 ccgtggttac cgtgttcaat tcaactcagc tgttggacca tacaaaggtg gacttcgttt
      661 ccacccaact gtaaaccaag ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa
      721 tgtcttgact ggacttccta tcggtggagg taaaggtgga tcagacttcg atcctaaagg
      781 taaaacagat gctgaagtga tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca
      841 catcggacca tcacttgacg tacctgctgg tgatatcggt gttggtggac gtgaaattgg
      901 ttacctttac ggtcaataca aacgtcttaa ccaatttgat gctggtgtct tgactggtaa
      961 acctcttgga tttggtggta gcttgattcg tccagaagca actggttacg gtttggttta
     1021 ctatactgaa gaaatgctca aagctaacgg taacagcttt gctggtaaga aagtcgttat
     1081 ttcaggttct ggtaacgttg ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac
     1141 tgttatttct gtttctgact caaatggtta tgtcatcgat gaaaatggta tcgacttcga
     1201 tcttttggtt gatgttaaag aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa
     1261 agcaactgca acctaccacg aaggtactgt atggacttac gctggaaact atgacattgc
     1321 tcttccatgt gccactcaaa acgaaatcaa cggtgaagca gctaaacgtt tggttgctca
     1381 aggcgttatc tgtgtatctg aaggtgccaa catgccgagc gaccttgatg ccatcaaagt
     1441 ttacaaagaa aatggtatct tctacggacc tgcaaaagct gccaacgctg gtggtgtagc
     1501 cgtttcagcc cttgaaatga gccaaaacag ccttcgcctc tcatggactc gtgaagaagt
     1561 tgatggacgt ctcaaagaca tcatgaccaa catctttaac acagctaaaa caacttcaga
     1621 aacatatggt cttgataaag actaccttgc aggagctaac attgctgcct ttgaaaatgt
     1681 agcaaacgct atgattgcac aaggtattgt ttaagattta tttactcaat cctcaatcac
     1741 tacgattggg gatttttagc ttgaattaaa aaattggaaa atctaattaa ataaaatgaa
     1801 atgaaataaa aactgaacaa attgattgcg gaattcaaac caatttctaa catatttcta
     1861 gaaattaatt tgacttttct aatcgatttg ttcatatctt atttcaattt actatactta
     1921 cttaaccctt tttatactca atgaaaatca aagagcaaac taggaagcga gccgcaggct
     1981 gtacttgagt acggcaaggc aaagctgacg tggtttgaag agattttcaa agagtattaa
     2041 acaaaaagaa aaaccgctac tcctaagaat agcgatttaa tcatattttt aagctactac
     2101 tgtaattgct ctattattta agtgttatga ataacttcaa tatctttaaa gctttttgtt
     2161 agatttataa ttccaactat agccatctct actccttagt ttacagcaaa aaattatgct
     2221 taattcttat tgtttttgta aacaatcagc gaacccaata ctattccatt caacaagcct
     2281 aaagaaatac catattcaac tggaaaatct aaaaaaattg caaacactat tccaatcatc
     2341 acccctagtg aggctgttgt taaaattaca tattcatttt ctttcttcat tttctttaca
     2401 cctcatttcc tttttgtata taagctgtag tactctccac caagctccat taagtactta
     2461 tgatttcctg actcaacaat cttaccacct ttcattacaa aaataatatc cgcatcctta
     2521 atcgttgaca atctatgagc tacaattatt tgagtacagc cctgactttt tatatacttt
     2581 gttattcttt cctcattaat agtgtctaaa gcactagttg cttcatctaa aattacaata
     2641 ctaggattat ttattaatgc acgtgccagt gctatccgtt gtctttgacc acctgaaata
     2701 tttgaaccca tctctgagat tatagtatta aatttcatcg gcatagccat gatttcatca
     2761 tagatttgaa ctgctttaca aacttcctct atcttttgtg aagtaacttc gtgctttaaa
     2821 gttatattat caagaatact tcggttcaat aaaaacgaat cctgtggaac tactcctaaa
     2881 ttttgactta atattttttt atctatttga ttaatattta caccatcaaa taaaactttt
     2941 cctgtatcaa tcttatataa tcctgatggt atttttgata atgtactttt tcctgacccc
     3001 ggttgaccga ctagtgcaat tctctgtcct gactcaatag tcaaatttaa attttctatt
     3061 acaggagctg agtctttgga ataagagaaa gataggtcct taatatctat tctacttcaa
     3121 acgtttctaa actatactcc ggaaaataat ttaaccaata actatctttc atcgtatcct
     3181 ccaaccagta ctaagagtct gggacaatag tctcttatct ccaaaaaaga agcggatttg
     3241 ccgttgcttt tttgcatggt tgcgatagtc ttggtaaaat agaattgccc aataaaccat
     3301 ttagaaaggc tatcccatgc atattcacta taacacaaat caaacaactt taccactaga
     3361 aatcagttct ttcttgccgc aagaccatca agaccatctc gtctttacta ttgaaaaagt
     3421 ggtgaatacc gatgaaaagg aggtaaacca tctgattaaa tatgccatgt ttgataagga
     3481 acaaaagaga ggctataaac agtcagctag aaacttagcg aattggcact ataatgacaa
     3541 ggaggatagc tatacacatc ctgatggctg gtattatcgt tttcaccata ccaaatatca
     3601 gaaaacacag acagactttc aacaagaaat caaggtttac tacgccgacg aacctgaatc
     3661 agcccctcaa aagggactgt atatgaacga acgctatcaa aacttgaaag ctaaagaatg
     3721 tcaggcgctt ttatctcccc aaggtagaca gattttcgct caacgcaaga ttgatgtgga
     3781 acctgtcttt gggcagataa aggcttcttt gggttacaag agatgtaatc tgagaggcaa
     3841 gcgtcaagtg agaattgaca tgggattggt acttatggcc aataacctcc taaaatacaa
     3901 taagagaacg actcaaaatt aaaaagctag agttccacaa ttggaaatct ttagcttttt
     3961 tgtgattgag aactattttg tcctagactc ttttgatttt taaagagaac ttaaatcatt
     4021 ctctaattaa agtaggaaga atacactaat ttagtaaagt aaatattaaa tttattttat
     4081 tttaaaatga tagtaggctc caagcatacc agcagtgttt tgatgatgag caaattctaa
     4141 tcttgtgttc tcagccaaac ttggaaccaa ggcttctttc aaggctgcac gaatctttgg
     4201 tttgaggata gcttcttgtc ccatgatacc acccccgaga atgaccacct ctggattgac
     4261 aacgtagtgt gtcataaata cctccttatg gattagagga agcgctcctt ggtttcacga
     4321 atcaaggctg cagccgcttc tacaactgga cgatcttctt cagtcactgg tgtcaatggt
     4381 gaacgaacag atccaatagt caagccttca ttgattttca aaacttcttt gatgacaccg
     4441 tacatatttc catgagcaga agtgagttta ccaatgattg cgttgatagc atactgcaat
     4501 tcacgcgctg tttctaggtc cttatccgca atcaactgat tgagtttcaa gaagagttct
     4561 ggcatagcac cataagtacc accgatacca gccctagcac ccatgaggcg tcctcctaga
     4621 aactgctcat caggaccatt aaagacgata tggtcttccc caccaaggct gacaaaggtt
     4681 tggatatctt gaactggcat agaagagttc ttaacaccga taacacgagg atttttcaac
     4741 atttctgtgt aaaggcttgg agtcaaagca acccctgcca attgaggaat gttgtaaatc
     4801 acgtagtctg tgtttggagc tgcagaactg atatcgttcc agtatttggc aactgagtat
     4861 tctggcaagc ggaagtaaat tggtggaatc gttgcaatag catctactcc caagctttca
     4921 gcatggcgaa caagttccat actatcttta gtattattgc aagcaacatg ggcaataatg
     4981 gtcaatttac ctttggctac cgccatgact tcttccaaaa tcaacttgcg atcttcaacg
     5041 ctttggtaga tacattcacc agaagaacca ttgacataaa gaccttgaac acctttatca
     5101 atgaagtatt gaacctaggc acgcgtacgc tctggactta cttctccttg ctcatcataa
     5161 catgcgtaga aggctggaat gacaccttcg tattttttca aatctgacat tgtttttttc
     5221 tccttatttc atactacgta attacatttc tagacttgag aacgaatatg ggactaattc
     5281 ctctaatcgc aattcaagta tgtttccctt accatttaat agaaagacta aggtatcagg
     5341 ctcacaaaat tctaccataa cttgacgaca aatgttgcat ggtggtaagt agtcttcagt
     5401 ttcacctgca acagcaatcg caagaatatc tccttttcta tatccttgag aagccccata
     5461 aaaaatagca ctacgttctg cacagttagt tacaccaaac gatacatttt ctatatttgc
     5521 tcctgtaatt actttaccat ctttaaataa aattgctgca cctacaggaa atttggaata
     5581 cggacagtaa gcatttttta aaactttttt tgcttgctcc attaaaacaa atttattaat
     5641 tactgtcatt gttttaactc
//
LOCUS       DAVHSL010000090         5258 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000090 DAVHSL010000000
VERSION     DAVHSL010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.092"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(404..1132)
                     /locus_tag="VVR39_002111"
     CDS             complement(404..1132)
                     /locus_tag="VVR39_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6031503.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1290..2699
                     /locus_tag="VVR39_002112"
     CDS             1290..2699
                     /locus_tag="VVR39_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6031504.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENAMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2717..4012
                     /locus_tag="VVR39_002113"
     CDS             2717..4012
                     /locus_tag="VVR39_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6031505.1"
                     /translation="MKNSKFIDQFAIFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            4017..4325
                     /locus_tag="VVR39_002114"
     CDS             4017..4325
                     /locus_tag="VVR39_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6031506.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4322..4630
                     /locus_tag="VVR39_002115"
     CDS             4322..4630
                     /locus_tag="VVR39_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6031507.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1776 a          882 c          953 g         1647 t
ORIGIN      
        1 cagaatttat ttaatatatt aaaagaagat atgaacaaat aaattgggag attgaaattc
       61 atttctagca attttttaga agtcacagtc tactattcta acctcaatat actatatgtg
      121 ttacaagaaa agactcaaaa acttctcgtc agtgtaagaa tgtttgaaac actatttaaa
      181 actaaataac tataagaagt agatcaggtg aacaatttca gtacctactc tataagctat
      241 acgaagatat ttttcaacat gatggataaa acgatcactc ttttaaagtc atcttattta
      301 gaaaagagaa accatttaag catagatggg accttcttgc cctgttttaa atttttctta
      361 aactagagcc tgtaaaagat tggcttcatt ttcacatttt ctcctaggag gaatgtcgta
      421 atgcaaaaga attaaattca aataaatcat agcgatgacg actaatcgag tactcaaacg
      481 gagttccgtt atccaaataa gccacttgtt ctacttcaaa taccggttcc gttggaagga
      541 gctgcaagta atgttgctca ttttctgaac tagaagaagc tcgtaagatt tttgtagcac
      601 tggcaatatg caatcctaac tttccttcaa tgtaattgta aatcgatttt tgtaaaatat
      661 cttcagtaat acctggaata acatcggtac tcatataagt ttgttccaga acataaggtt
      721 taccgtcaat aatacgcagg cggtaaatat tataaactgg actctgcaaa gcgacctgta
      781 gtttttctgc taaaaattca tttgcaaatt ctaatttgaa gtgaataatc ctcgagtcaa
      841 ttgtagaatg agcatcttca gatatttttg tcagtccccg gatatctctt tctggaacga
      901 ttaattttct ttttgagctg ccacgagaga gaacaaaggt tccctgccca cgttttctaa
      961 aaattaagcc ctcagaaact aacaagtcta aagctttttt gatcgtcatt cgactacagg
     1021 caaactgttt agctaatgtc atttcatcag gcaattgttc gttcatggta tatttattac
     1081 aaagaatctt ttcacgaatc tcattgtaaa taaataaata ttttgtactc atttaatctg
     1141 gttctctcta taatattcta atagtagtat aacaaagttc aagaaatgag gcaaacacaa
     1201 gatatgtatc aacaattttt aaaaatgtct agacaaattt taaaattatg ctatacttta
     1261 tgtataggat aatagaaagg aggttgagca tgaaaaaaaa gttagtattt cctaatctgt
     1321 tttggtgggg agctgcttct agcggacctc agacagaagg tcaatatgga aaagtacatg
     1381 aaaatgcgat ggactactgg ttcaaaacgc atccagaaga ttttttcgat aatgtcggac
     1441 ctcttgtagc cagtaacttt tttcatactt acaccgaaga tttccacttg atgaaggaaa
     1501 ttggagttaa ttctttccgc acttccatcc aatggagtcg actcatcaag aatttagaga
     1561 caggtgagcc tgatccaaaa ggtattgctt tctacaatgc catcattgaa gaagctaaaa
     1621 agaaccagat ggatcttgtg atgaatttac atcattttga tttaccagtg gaacttcttc
     1681 aaaaatacgg tggttgggaa agcaaacatg tagtggagtt attcgtgaag tttgccaaga
     1741 ctgctttcac atgctttgga gataaggttc attactggac aactttcaat gagccaatgg
     1801 tcattccaga agcaggatac ttatatgctt tccattatcc aaatctaaaa ggaaagggaa
     1861 aagaggccgt acaagtcatc tataatctaa accttgctag tgcaaaagtg attcaactat
     1921 atcgctcatt aggacttgat ggaaagattg ggattatttt aaacttgaca cctgcttatc
     1981 caagaagtaa ttctccagaa gacttagaag caagtcgatt tacagatgac ttctttaaca
     2041 aagtcttctt gaatccagct gttaaaggaa ctttcccaga aagattggta aaacagctag
     2101 agagagatgg cgtgttatgg agtcataccg aaaaagagct tcaactgatg aaatcaaata
     2161 cggttgattt tcttggagta aactactacc atccaaaacg tgttcaagca caagcaaatc
     2221 ctgaggaata tcagacgccc tggatgccag accaatactt caaagagtat gaatggccgg
     2281 agcgtcgcat gaatccatat cgtggttggg aaatttttcc gaaagccatt tatgatattg
     2341 ctatgattgt gaaggaagaa tatggtaata tcccatggtt tatcagtgaa aacggaatgg
     2401 gtgttgaaaa cgaagcacgg tttatcgatg aaaatggagt tatcgatgac gtgtatcgta
     2461 ttgaatttta tgaagaacat ttaagatggc tacataaagc cattgaagag gggagtcact
     2521 gttttggata ccacgcttgg accgcatttg attgctggtc ttggaataat gcatataaga
     2581 atcgttacgg atttatctcc gttgatttag aaacgcaaaa gagaaccatc aagagctcag
     2641 gaagatggta tcgcaaagta agtgacaaca acggttttga agtagaaatt gaggagtaaa
     2701 gagaggagat attcagatga aaaactcaaa atttatagat caatttgcca tctttgctgg
     2761 taaactaggg aaccaaattc atttaaaaac cctaagagat gcattcgtaa cagtaatgcc
     2821 attatatatt ttggcaggtt taatcgttct tttgaacaac acggtattta agtggatttt
     2881 ccaaggggat acattaacaa aattccaata ttggggaata acaattgcaa acggtacttt
     2941 aagtatttca ggtatgatta ttgctgtaat ggttggttat ttcttagcta aaaacagaga
     3001 tttcgaaaac ccgttagcag catcaatgct atcattagtt tctttaattg tgatgatgcc
     3061 aaatacagtt tctgtagttc ctgacggagc aaaagatgct gtaaacattt caggtgttct
     3121 ttcattcaac aacacaggta caggcgcaat gttcgccggg gttatcgtag cgattattgc
     3181 aacagaatta ttcattgaat tatcaaacgt taaagcttta caaatgaacc ttggtgaaaa
     3241 tattccacca gctgttagta gatcatttag cgtattactt ccagtcatga ctgtcatctc
     3301 cttatttggg attgtttcag cattattatt caatataact ggaatgaact taatctcaat
     3361 cattacaatc tttattcaag aaccaattcg tcatattggt acaagcttaa tcggggtcat
     3421 tattatttac tctttaggaa atatgttatg gctatttggt attcaccaag cagttattta
     3481 cagtgccatc ctagaaccat tactattaat taacattact gaaaacatca ctgcagcaaa
     3541 taatggacaa gccattccac acatcatcaa cttatcacaa atacaaacat tcgctttaat
     3601 gggtggtagt ggatctacat tatgtttatt aatagcaaca ttcttagtga gtcgcaatgc
     3661 tgtttctaaa aacgtggcta aattatcttt tggacctggt atcttcaata tcaatgaacc
     3721 agtattattc ggttacccaa tcgtttataa catttcatta gctattccat ttatcacagt
     3781 tccagtcctt ggtattttaa tcagctactt agcaacagtt acaggattca tgagtcctgc
     3841 atttatacaa gttccttgga ctacaccagt attcttaaat gcatggttag caacagcagg
     3901 ggacgtgaga gcagttctag ttcaattcat catctttgca cttggagttc ttctatacat
     3961 tccatttatc aaagttaatg acaaagttgt tgagcaagaa atggaaggtt aagattatga
     4021 aacaaatttt attagtatgt aatgcgggaa tgtcgacaag tatgcttgtt aaaaaaatgc
     4081 aacaaagtgc gactgaacgt gggattgaaa tctctatcca agcaaaatca atgacagaag
     4141 ctaaaaagaa tatccatgaa gcagatgtca ttctaattgg gccacaaatt cgttatgagt
     4201 tacttgctgt gaaagaaatt gcaggaaata tccctgtaga taccattgat atgcgggatt
     4261 acggaatgat gaatggagca aaagttctgg aacaagcact tgcatggata ggagaaataa
     4321 gatgacagaa gaaatggaat atatctgttt tcagctcatt gccaatagtg gagcagccaa
     4381 atcatccttt attgaagcca tccaactagc taaggcagga aatttaaaag aagcgaaaat
     4441 taaagttgaa gaagcggaag actccttagt agaagcgcac aagattcact ctaatctcat
     4501 acaaaaagaa gctactggag aaaaaatagg attctccttg ctatttatgc atgcagaaga
     4561 ccaaatggct tcaacagaga ttattcagtt actatctaaa gaattcatcg atctctatca
     4621 aaataaatag gaacactgtc attcccatct gtctttatta atgacgacta cattgtagga
     4681 acctccaaaa gttggacaaa atgattgaaa ggattggatc ctgcattaca caagatccaa
     4741 tccttttctt ttactctagt ttttataata tgttgaatct agaatagtcc actgcagttt
     4801 ctaaaaaatt tctggaaatg gatgttaagc tccaatttat ttgtttatat cttatttcag
     4861 tttactatac tagcttatta ttctagtgaa aaattgaatg agccactatt tatttaatat
     4921 gtatgatgag ggaatgactc aaaaacttct tgtcgatata agaacatctg agatagtatt
     4981 ttaaaacgaa aggactataa aagctcattt ccttcgcact tattttatag agatctatca
     5041 ttatactctt tagaaatcaa aaagcaacac accttgtcat cgttttatcg taaatctgtt
     5101 aatgaggggg ctagtcttat ctgcaatctc aaatcagtgt tttgagctga atggcactcg
     5161 ttttctcgtt tgctctttga ttttaattgg gccttagtaa atactactct taaattaaac
     5221 tatagtgaat tgaaataaga tgtgaacaac tctatcag
//
LOCUS       DAVHSL010000091         5044 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000091 DAVHSL010000000
VERSION     DAVHSL010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.093"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(222..1637)
                     /locus_tag="VVR39_002116"
     CDS             complement(222..1637)
                     /locus_tag="VVR39_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6031508.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDKEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLKRYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1650..3488)
                     /locus_tag="VVR39_002117"
     CDS             complement(1650..3488)
                     /locus_tag="VVR39_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6031509.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3506..4345)
                     /locus_tag="VVR39_002118"
     CDS             complement(3506..4345)
                     /locus_tag="VVR39_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6031510.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4646..4828)
                     /locus_tag="VVR39_002119"
     CDS             complement(4646..4828)
                     /locus_tag="VVR39_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6031511.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGEVDEMTIL
                     RLESASIVSELVAGLR"
     gene            4887..>5044
                     /locus_tag="VVR39_002120"
     CDS             4887..>5044
                     /locus_tag="VVR39_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031512.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKG"
BASE COUNT         1701 a          966 c          664 g         1713 t
ORIGIN      
        1 gttttagcaa ttatttcgta ctattttaga ttcagtctac tatatataac caatctatcc
       61 taagttaact atttataatc ggctctctgt aacaaaatta aattaattaa tccccctatg
      121 aaataaagag gtttagaatt tgatgtcttc caaacctctt tatttcatat tcaatgagat
      181 gttgccttaa ccgtgataat atctaatcat caataaacaa actatttgaa taaggattct
      241 ccatttgatt caatcactcc tttataccaa gtaaaggaca ttttcttata tcgattgaat
      301 gtgccatttc catcatcatt tcgatcaaca taaatgagac cgtacctctt agaaagctgt
      361 gcagtggaca tagaaacgca gtcaatacat ccccaagacg tatagcccat aatttccaca
      421 ccatcttgta gagcttcagc tacttgcaat aaatgttctt tcatatactg aattctataa
      481 tcatcttgga ctgttaagtt attaaattca tcttttatta gttgatcttt agcacctaat
      541 ccgttttcca ctataaataa tggaatttga taacggtcat aatatctatt taaaattata
      601 cgtagtccaa ttggatcaat ttgccatccc cactctgaag actctaaata aggatttact
      661 aaaccaccaa taatattccc ttctcctgaa ttatactgtg ttggaagagc agattgagtc
      721 acactcatgt aatagctaaa ggataaaaaa tctacggtat aattttttaa taactctgca
      781 tcttcagctg caaactctat gttaatgtca tgttccttaa aatatctttt tgcataattc
      841 ggataataac ctctaacatg cacatctgaa aatagataat ttagattctc atactcatga
      901 gtcgcccata catcttttgg atttggagtc attggataag ctggcatagc taataccata
      961 caccccacct taaactctga attaatctca cgagcaattt ttgtaaccaa actcgaggcg
     1021 actaattcat gatgtatagc ttgatataat tcttgtttcg aaagattctc cttaggtata
     1081 tctattcctc cactagtaaa cggtaattcc aaaacagagt ttacttcgtt aaatgtaagc
     1141 caatatttaa ctttatcttt ataccttttt aaaactgttc gagcaaattt ttcataaaaa
     1201 tgaatcattc tcctatcaat ccatccatga tattttcttg ctaaatataa tggagtctca
     1261 tagtgtgaaa gagttacaag tggttctatc ccgtgagcat gtagttcatc aaataattca
     1321 tcataatatt tcaaaccagc ttcgttaggt tcttccttat ctccttttgg aaaaattcta
     1381 ctccatgcaa tagaagtacg aaaaacatta aagcccattt cagaaaacaa ggatatatct
     1441 tccttatatt tatgataaaa atcaatacct aacaacttta agttatcttc tgtaggattt
     1501 tctgttgctt ctcctaatcc acctttgggt aacacatcct gaactgataa tcccttacca
     1561 tcttcattat atgctccctc tacttgatta gctgcaacag ctccacccca aagaaaatca
     1621 tctggaaaaa tggtcataac tttcctccat tataatatta ccagtaattc cttagaatgc
     1681 tcgattgtct gattattagg taatactaat acatctagaa aatcattggt attcgttaca
     1741 attactggtg taactgtttc gtagccttta gtcttgatta aattcaagtc catttcaaaa
     1801 atcaactgat ttttgaaaac tctgtctcct tcttctacat gactaataaa accttgacct
     1861 tttagctcaa cagtatctaa tccaatatga attagtaact caacaccctc atcactcttc
     1921 aatccaattg cgtgcttagt cggaaaaata tttgtaattt tcccatcaaa tggtgcataa
     1981 accttacctt cacttgggat aatcgctact ccgtctccaa ttagtttatc tgaaaatgtt
     2041 ttatcctgga catcgcttaa cggaatgatt tctcctgata taggagaaaa tatcattttt
     2101 ttatttgaaa ctccaacttc aacttctaaa ttgctagaac tctcttcttc atcgattcca
     2161 aatatataag ctaatacaaa ggtaataaca accgaaatga ccgccacaat taaagcattt
     2221 acaatatttg atggcacatc agaataaata aattgaggca acgctatcaa agatgggaca
     2281 gcaaatagat atgctttaac actagtaaga cctgcaaata atcccgctaa tccaccacca
     2341 atcatagctg cataaagcgg ttttttatat tttaaagtca caccatataa tgcaggttcg
     2401 gtaatccctg caagtaaggc tgagaaacct gctgcaaaag caatttgttt tgtattatta
     2461 tttttactct ttaatgcaac agccatcgaa gcagcccctt gagctaagtt tgaccctaac
     2521 attgctggaa gaattaatac gtctggagta gcaatagatg ccgccaaaaa aataggtgca
     2581 aaagcccaat gcattccagt cataacaata aatggcataa tagcaccaag aatagctaat
     2641 gtaagccatc cagctacacc atacatttgc ccaactagat ttgataatcc ttcaccaaca
     2701 attactccaa taggtccgac tacaactaag gcaatacagc ttgatactaa taatactagc
     2761 gtaggttgca aaaaactctt agtaacagct ggtgttaatt tagcaatcat tttttcaata
     2821 tatttcatca accaaaccat aataagaatt ggaacgactg acgaaccata actagctggt
     2881 gtcacaggta caccaaataa actaagagga ttccctgatt gcaccatttg aacaaaattt
     2941 ggatggagaa gtacacctgc tacagacata gctaatgtag atgttacttt taatttttgt
     3001 gatgcagaat aagctaataa cagcggtaag aaataatatg gagcatcccc aaaaaatgtc
     3061 aaaaaagcaa tagtctgaga atctgattgc aatataccaa gcattggtaa aataattacc
     3121 aagactttca gcatacctcc ccctaacatt gctggaatga ttggagtcat ggaaccagcg
     3181 atatactcaa tgattctttc taaaatattc cctttgtgcc cttgaacaac tgaatcggat
     3241 tcaaaattgc caagtttaac gaattcttta taataattag ctacatcatt accaagtata
     3301 atttgatatt gtccattctt tttcataata cctattacac ctggtatctt cttcacatca
     3361 tcatcattga ctaaattttc atcttttaat tctaatctta aacgtgttac acaatgggta
     3421 actctattga catttttttc acctccaatt acatcgagga ttttttgtac cgtatcttta
     3481 taactcatgg tattctccta ttctattaat ctaaattttt tgttaagcga cgaatatgag
     3541 ccatcaaata aactaattca ctagaagtca gcaaataatt gtactcagtt tgtataaaca
     3601 ttgccacctg ttcaccacat tcatattctc taggatattt atttttcatt aatgctaaca
     3661 agtcttcatc atcatcgtca caataagttg tattttcaac caagcgatgg gcaaataatt
     3721 ttatatgagt tatgaatcta taataatcaa tagaatcttg gttaaactca gtacaataga
     3781 aatcttgaat gattttctca attcccataa ttatttcagt gattttatac gactcttgaa
     3841 aattattttc taaattagca ttaacaaaat gtagcgctat gaatgcagct tcgtcaattg
     3901 gaagttcaat acctaactct ttttttatta tttgtaaagc ccttttccca agctcaaatt
     3961 cttctttata atatttcgag atttcccagc gtaggggatt cgaaataata actccttctt
     4021 tataacgttc tatactcgaa gaaatatgat ccgttagatt tatatagata atctcatcaa
     4081 aattattacc taatgttatt ttacctagat taattatttt ttcggtgatg tacaccaact
     4141 ccaaaggaac gttaataaac atctctgtaa aacgggtcat gttatctcta tttttgagaa
     4201 aaaaactttt ctcaatatca attggattta ctttatctcc aatttttctt ccaaaagcta
     4261 ttccccttcc aaaaagaaga atatcgatat cttttttact ttgcgcaatt acggcattgt
     4321 ggtttagtat tcgttttatg atcataaaat ttccctttta aaataaaagg aacctactta
     4381 aaaaacatca agaaacttct tctgatgtga ttaaataggt tcctgctcac ttgtattagt
     4441 gataacatcc ttttatttca atttttaatg gtgacatgaa gcttaaataa ttaataactc
     4501 tgtaaccgtt tttattttat gatatttcaa tctatttgtc aagtacttat aaaaattttt
     4561 ttattttgtg tgattcgaat gtgataatgg caacagtctc actaaagaaa tgaaaatcat
     4621 acatagaaat ttttaaaaat tttctctatc gtaaacctgc cactagttca gaaactatac
     4681 tagctgattc caaacgtaat atggtcatct catctacctc ccctaataat ggcattgcac
     4741 cataccaaac aatagtctta ttcaccaaaa gaataggcgt tactattttt gattgagtaa
     4801 aagacacttt aattttctgg ctcttcaact gtgaactaca ccccaaaagt tagacagaaa
     4861 aaatctaact tttggggtgt tttattatga aactaactta tgatgataaa gttcagatct
     4921 atgaacttag aaaacaagga tatagcttag agaagctttc aaataaattt gggataaaca
     4981 attctaatct taggtacatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa
     5041 aagg
//
LOCUS       DAVHSL010000092         4862 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000092 DAVHSL010000000
VERSION     DAVHSL010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.094"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..1537
                     /locus_tag="VVR39_002121"
     rRNA            <1..1537
                     /locus_tag="VVR39_002121"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1589..1661
                     /locus_tag="VVR39_002122"
     tRNA            1589..1661
                     /locus_tag="VVR39_002122"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1622..1624,aa:Ala,seq:tgc)
     gene            1786..4687
                     /locus_tag="VVR39_002123"
     rRNA            1786..4687
                     /locus_tag="VVR39_002123"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4764..>4862
                     /gene="rrf"
                     /locus_tag="VVR39_002124"
     rRNA            4764..>4862
                     /gene="rrf"
                     /locus_tag="VVR39_002124"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1344 a          999 c         1445 g         1074 t
ORIGIN      
        1 agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca agtagaacgc
       61 tgaaggagga gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc gtaggtaacc
      121 tgcctggtag cgggggataa ctattggaaa cgatagctaa taccgcataa gagtggatgt
      181 tgcatgacat ttgcttaaaa ggtgcacttg catcactacc agatggacct gcgttgtatt
      241 agctagttgg tggggtaacg gctcaccaag gcgacgatac atagccgacc tgagagggtg
      301 atcggccaca ctgggactga gacacggccc agactcctac gggaggcagc agtagggaat
      361 cttcggcaat ggacggaagt ctgaccgagc aacgccgcgt gagtgaagaa ggttttcgga
      421 tcgtaaagct ctgttgtaag agaagaacga gtgtgagagt ggaaagttca cactgtgacg
      481 gtatcttacc agaaagggac ggctaactac gtgccagcag ccgcggtaat acgtaggtcc
      541 cgagcgttgt ccggatttat tgggcgtaaa gcgagcgcag gcggttagat aagtctgaag
      601 ttaaaggctg tggcttaacc atagtaggct ttggaaactg tttaacttga gtgcaagagg
      661 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccggtgg
      721 cgaaagcggc tctctggctt gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      781 gattagatac cctggtagtc cacgctgtaa acgatgagtg ctaggtgtta gaccctttcc
      841 ggggtttagt gccgtagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      901 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      961 agcaacgcga agaaccttac caggtcttga catccctctg accgctctag agatagagtt
     1021 ttccttcggg acagaggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
     1081 ttgggttaag tcccgcaacg agcgcaaccc ctattgttag ttgccatcat ttagttgggc
     1141 actctagcga gactgccggt aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat
     1201 gccccttatg acctgggcta cacacgtgct acaatggctg gtacaacgag tcgcaagccg
     1261 gtgacggcaa gctaatctct taaagccagt ctcagttcgg attgtaggct gcaactcgcc
     1321 tacatgaagt cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg
     1381 ggccttgtac acaccgcccg tcacaccacg agagtttgta acacccgaag tcggtgaggt
     1441 aaccgtaagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg
     1501 tagccgtatc ggaaggtgcg gctggatcac ctcctttcta aggataagga actgcgcatt
     1561 ggtcttgttt agtcttgaga ggtcttgtgg ggccttagct cagctgggag agcgcctgct
     1621 ttgcacgcag gaggtcagcg gttcgatccc gctaggctcc attggtgaga gatcaccaag
     1681 taatgcacat tgaaaattga atatctatat caaatagtaa caagaaaata aaccgaaaac
     1741 gctgtagtat taataagagt ttatgactga aaggtcagaa aataaggtta agttaataag
     1801 ggcgcacggt ggatgccttg gcactaggag ccgacgaagg acgtgacaaa cgacgatatg
     1861 ccttgggtag ctgtaagtaa gcgatgatcc agggatttcc gaatggggga acccaacagg
     1921 tagtacctgt tacccacatc tgttaaggat gtgaggagga agacgcagtg aactgaaaca
     1981 tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg
     2041 gcaggagggc aaaccgaaga gtttactctt cggggttgta ggactgcaat gtggactcaa
     2101 agattataga agaatgattt gggaagatca gccaaagaga gtaatagcct cgtatttaaa
     2161 atagtctttg tacctagcag tatcctgagt acggcgggac acgtgaaatc ccgtcggaat
     2221 ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga accagtaccg
     2281 tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc
     2341 tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat gaaccggcga
     2401 gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac cgagtctgaa
     2461 tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca tgagcaggtt
     2521 gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag tgcttggatg
     2581 acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata
     2641 gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt tgggtgaggg
     2701 gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta tggtcggcag
     2761 tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc accagctaag
     2821 gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac taggatgtta
     2881 gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga gtgaccctgc
     2941 gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt tataggtatg
     3001 gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga acgcatagaa
     3061 gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc gtaagactaa
     3121 ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag agaccgaaag
     3181 gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg atggagggac
     3241 gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga ggtgtgaatt
     3301 gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt tagtagcgaa
     3361 gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc tacccgtacc
     3421 gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa
     3481 ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt aagtcagccg
     3541 cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa atcgtaagat
     3601 gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag
     3661 cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag
     3721 cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt
     3781 ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac ccgcgacagg
     3841 acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta ccacatgtac
     3901 aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc tgttgggata
     3961 ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga gacagtgtct
     4021 gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc
     4081 cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct tgactgcgag
     4141 agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag
     4201 ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc ccccaagagt
     4261 tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt
     4321 cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt
     4381 cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg atctgctcct
     4441 agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc caaaggcatc
     4501 gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg aaacccacct
     4561 caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga tcaggtagat
     4621 aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag ctcgaggact
     4681 tatccaaagt aactgagaat atgaaagcga acggttttct taaattgaat agatattcaa
     4741 ttttgagtag gtattactca gagttaagtg acgatagcct aggagataca cctgtaccca
     4801 tgccgaacac agaagttaag ccctagaacg ccggaagtag ttgggggttg ccccctgtga
     4861 ga
//
LOCUS       DAVHSL010000093         4507 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000093 DAVHSL010000000
VERSION     DAVHSL010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.095"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..242
                     /locus_tag="VVR39_002125"
     CDS             <1..242
                     /locus_tag="VVR39_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031513.1"
                     /translation="LPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEY
                     NPIEKTWAHIKKNLKKVLPSCNTFYEALLSCSCFN"
     gene            complement(235..408)
                     /locus_tag="VVR39_002126"
     CDS             complement(235..408)
                     /locus_tag="VVR39_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU6031514.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFGGNPTTF
                     NYLLDYYADNTVN"
     gene            complement(567..2174)
                     /locus_tag="VVR39_002127"
     CDS             complement(567..2174)
                     /locus_tag="VVR39_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU6031515.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENKKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTDQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2327..3811
                     /locus_tag="VVR39_002128"
     CDS             2327..3811
                     /locus_tag="VVR39_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU6031516.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3906..4388
                     /locus_tag="VVR39_002129"
     CDS             3906..4388
                     /locus_tag="VVR39_002129"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU6031517.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1318 a         1025 c          854 g         1310 t
ORIGIN      
        1 tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga ttccatagaa
       61 tggggaagtt agaactttta tgcgaagagt ttgggcataa acttttacct cttcctccct
      121 actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag aacctcaaaa
      181 aggtattacc aagttgcaat accttttacg aagctctttt gtcttgttct tgtttcaatt
      241 gactgtatta tcagcgtaat agtctaatag atagttaaat gtagttggat ttccaccaaa
      301 ggttgatgag taagtttttg tatctgaacc tgattggccg caagcagcta aaagcaaagc
      361 agatgcaaaa gtcaggcctg cactaaggac acgcttcttt atgttcatct tctttctcct
      421 taatagtggg aatttgtaaa gttaattgaa tttcgagaat gaaagtttat aaaccttggt
      481 tataaaaaac aaaggatttc cgccttttat acagtcctcc cttgttttta tatgatttca
      541 attttaaatt tttctgcaaa aaatatttat agtaattcca cacagaaagc atcccatgga
      601 actaagattt gtttttcaaa gacttcttga gctagggtgt tttcaatcaa gacagatttg
      661 acttttcctt ctactgtcaa gtcttgctct tcattggaca agttagccac aactaggaag
      721 cgacggtcgc catccttacg tatataagca aagaccttat cagccgtatc aagcaattca
      781 aagtcagctc gaattaacca gctattctcc ttgcgaattt ggaccagttt ctgataggta
      841 tagaaaatag aatctggatt tgccagcgct tcttggacgt tgatcatctc gtaatttgga
      901 ttaactgcca accaaggttg atctgttgaa aaaccagcgt ttttgctctc gtcccattgc
      961 ataggggtac gggcattgtc acgtccaata acacggatac tgtccatgat ttcttcaatc
     1021 ggaacacctt tttcaagagc ctcacgcgca tagttgaggg attcaatatc ttctacttga
     1081 tctagtgttt caaacggata gttggtcatc ccaatctcct caccttggta gatataagga
     1141 gttcctctca tgagatgaag taagattgca aaggctttgg cagatttttc gcggtattct
     1201 tggtcatttc cccagattga gacaatacga gggaggtcat ggttgttcca gaagagggaa
     1261 ttccagccgt cctcaactcc taactctgtc tgccatttgt tgaagatttc ttttaactta
     1321 gcgatattca gctctttttg atagtgccat ttaggctgac cttcctgata ctgaagaccg
     1381 atatgttcaa actggaagac catagacaat tcttgcccct ttggatcaga gtagagcttg
     1441 gcaatctctg gcgttgctcc ccaagtctcc cctactgtca agagatcctt atctccaaag
     1501 gtcgcctgat tcatttcctt gagataggga tggagcatag gaccattatt gactaccttc
     1561 tcgtcaggaa ttttgccaat catgtcaata acatccatac ggaaaccacc aataccttta
     1621 tcaatccaga agttcatcat ctcataaatt ttctggcgaa gttttttatt ttcccagttg
     1681 agatccggct gtttcttgct gaaaaagtgg agatagtatt gacctgactt ttcatcgtat
     1741 tcccaagcag acccactaaa gatagaatct aggtcattgg gttcatcgcg ccagatatag
     1801 tagtctcgct cagggctgtc agtattttca caagcttcga caaaccaagc atgttcatct
     1861 gaggtatgat taaccaccaa gtccatgatg atacgaatgt cacgcttctt agcttccgca
     1921 atcagttgat ccatatcctc catggttcca aaaatcgttg caatcgcttg ataatcagca
     1981 atatcgtagc cattatcatc catagggctg tcataaacgg gagaaagcca aatcgctgtg
     2041 attcctagct tagctagata gtccaactta ctggtaatac ctggcaaatc accaactcca
     2101 tctccattac tatccataaa actctttgga tagacttgat agactacggc attatgccac
     2161 catttttctt gcatctgttt acctcattat tttaataatc tatagtatat gatagcactt
     2221 tttaaaattt tgtgcaagcg tttgcttaat ctttttaatt tcttttttag ctccgtagtt
     2281 tcctaacttc caatttttta ttataataga gtccagaggt aaaaaaatga aaaaacaagc
     2341 ttttagttct gaacagtatt tgaatttaca acgcgaccat attttggagc gcattaacca
     2401 atttgacggc aagctctact tagagtttgg cggtaaaatg ttagaagatt tccacgctgc
     2461 tcgtgtcctt cctggttatg aacctgacaa caaaatcaag ctcttgcaag aattgaaaga
     2521 gcaggttgag gttgtgattg ccattaatgc tagcaacatt gaacattcca aagcacgtgg
     2581 cgacttaggc atttcttatg accaagaagt tcttcgtttg attgacaaat tcaatgaatt
     2641 agggattttt gttggttccg ttgtcattac acaatacgct ggccaacccg ctgcagatgc
     2701 cttccgcaac caacttgaga aaaacggaat tgattcttat cttcattatc caatcaaagg
     2761 atatcctacg gatatggatc acatcatttc cccagaaggc atgggcaaaa acgactacat
     2821 caaaaccagt cgcaacttga ttgtcgtaac cgctcctgga cccggttctg gaaaattggc
     2881 aacgtgtatg tccaatatgt accacgacca aatcaatggc atcaaatctg gctacgctaa
     2941 atttgaaacc ttccctgttt ggaatcttcc ccttcatcat ccagttaact tggcttatga
     3001 agctgccaca gctgaccttg atgatgtcaa catgattgac cccttccatc ttcaaaccta
     3061 tggagaaacc actgtcaact acaaccgtga tatcgaaatc ttcccagtgc tcaaacgcat
     3121 gttggaacgt attctcggaa aatcaccata cgcttcaccg acagatatgg gtgtcaacat
     3181 ggttggtttc gctattacag atgacgaggc tgctgtcgaa gcttctaaac aagaaatcat
     3241 ccgccgttac tatcaaacag ttcttgactt caaagctgaa aaagttggcg aagctgccgt
     3301 caagaaaatt gagttgctca tgaacgacct cggtatcaca cctgcagatc gtaaggttgc
     3361 tgtcgttgcg cgccaaaaag cagaagaaac tggtggacca gccctagcct ttgaattgcc
     3421 aaatggggaa atcgtcactg gtaagaactc agaactcttt gggcctacag ccgctgcctt
     3481 gatcaacgcc atcaaaaaat cagctgacat cgctaaagaa gtaaaactaa tcgagcctga
     3541 agttgttaag ccaatccaag gtcttaaaat cgatcatctc ggtagccgca atccacgcct
     3601 tcattcaaat gaaatcctga ttgcacttgc tatcacagct acagaaaatc ctgatgctgc
     3661 ccgcgctatg gaagaactcg gcaacctcaa aggaagcgaa gcccactcaa ccatcatctt
     3721 gactgatgaa gacaagaatg tccttcgtaa actgggtatc aacgtaacct ttgacccata
     3781 ctaccaatac gaccgcttat atcgtaagta aagatttcaa cctctccagc ctcggagagg
     3841 ttttctctct gtctcaggag caacctttat gatataatga gagaagaaaa ctgaaaggat
     3901 ttaccatgtc aaaagaagtt attgtcgaaa gttttgaact tgaccacacc attgtcaaag
     3961 caccctatgt tcgcttgatt ggggaagaaa caggaccaaa aggagacatc atctccaatt
     4021 atgatattcg cttggtgcaa ccaaacgaag actctatccc tactgccggt cttcacacta
     4081 tcgagcacct cttagccaaa ctcatccgta cccgcattga cggcatgatt gactgttcac
     4141 catttggttg ccgcacaggc ttccacatga ttatgtgggg acgtcacacc agtgctaaaa
     4201 tcgcagctgt tatcaaggat tcgctcaagg aaatcgctga aactactact tgggaagatg
     4261 tcccagggac aaccatcgaa tcttgcggaa actacaagga ccacagcctc ttctctgcta
     4321 aagaatgggc aaaactcatc ttggaacaag ggatttcaga tgatgccttt gaacgtcatg
     4381 tgatttaaaa tcgagtaggg gataatctct agcccctctc acaccaccgt acgtgccgtt
     4441 cggcatacgg cggttcaact aacttttaac gcatgtcgtt caaggtaata atccaaacac
     4501 gaaacca
//
LOCUS       DAVHSL010000094         4243 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000094 DAVHSL010000000
VERSION     DAVHSL010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.096"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..782
                     /gene="phtD"
                     /locus_tag="VVR39_002130"
     CDS             <1..782
                     /gene="phtD"
                     /locus_tag="VVR39_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU6031518.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPS
                     ADNLYKPSTDTEDTEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNA
                     VETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            992..4111
                     /gene="phtE"
                     /locus_tag="VVR39_002131"
     CDS             992..4111
                     /gene="phtE"
                     /locus_tag="VVR39_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU6031519.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1582 a          707 c          831 g         1123 t
ORIGIN      
        1 accatcagga ttcaggaaat actgaggcaa aaggagcaga agctatctac aaccgcgtga
       61 aagcagctaa gaaggtgcca cttgatcgta tgccttacaa tcttcaatat actgtagaag
      121 tcaaaaacgg tagtttaatc atacctcatt atgatcatta ccataacatc aaatttgagt
      181 ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat cttttggcga
      241 ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcagataat ggttttggta
      301 acgctagcga ccatgttcaa agaaacaaaa atggtcaagc tgataccaat caaacggaaa
      361 aaccaaacga ggagaaacct cagacagaaa aacctgagga agataaggaa catgatgaag
      421 taagtgagcc aactcaccct gaatctgatg aaaaagagaa tcacgctggt ttaaatcctt
      481 cagcagataa tctttataaa ccaagcactg atacggaaga tacagaggaa gaagctgaag
      541 atactacaga tgaggctgaa attcctcaag tagagcattc tgttattaac gctaagatag
      601 cagaggcgga ggccttgcta gaaaaagtaa cagattctag tattagacaa aatgctgtgg
      661 agacattgac tggtctaaaa agtagtcttc ttctcggaac gaaagataat aacactattt
      721 cagcagaagt agatagtctc ttggctttgt taaaaaaaag tcaaccggct cctatacagt
      781 agtaaaatga atggagcata ttctatggag aagtaacctt tcgtgttact tctctttttt
      841 agaaaaacgt aacagaaact tgacaaaagt aattttaaat agtaaactat ttactggtta
      901 attaaatggt taaataaccg gtttagaaaa ctatttaata aagtaaaaga agttgagaaa
      961 aaacttcatc atttattgaa atgagggatt tatgaaattt agtaaaaaat atatagcagc
     1021 tggatcagct gttatcgtat ccttgagtct atgtgcctat gcactaaacc agcatcgttc
     1081 gcaggaaaat aaggacaata atcgtgtctc ttatgtagat ggcagccagt caagtcagaa
     1141 aagtgaaaac ttgacaccag accaggttag ccagaaagaa ggaattcagg ccgagcaaat
     1201 tgtaatcaaa attacagatc agggctatgt aacgtcacac ggtgaccact atcattacta
     1261 taatgggaaa gttccttatg atgccctctt tagtgaagaa ctcttgatga aggatccaaa
     1321 ctatcaactt aaagacgctg atattgtcaa tgaagtcaag ggtggttata tcatcaaggt
     1381 cgatggaaaa tattatgtct acctgaaaga tgcagctcat gctgataatg ttcgaactaa
     1441 agatgaaatc aatcgtcaaa aacaagaaca tgtcaaagat aatgagaagg ttaactctaa
     1501 tgttgctgta gcaaggtctc agggacgata tacgacaaat gatggttatg tctttaatcc
     1561 agctgatatt atcgaagata cgggtaatgc ttatatcgtt cctcatggag gtcactatca
     1621 ctacattccc aaaagcgatt tatctgctag tgaattagca gcagctaaag cacatctggc
     1681 tggaaaaaat atgcaaccga gtcagttaag ctattcttca acagctagtg acaataacac
     1741 gcaatctgta gcaaaaggat caactagcaa gccagcaaat aaatctgaaa atctccagag
     1801 tcttttgaag gaactctatg attcacctag cgcccaacgt tacagtgaat cagatggcct
     1861 ggtctttgac cctgctaaga ttatcagtcg tacaccaaat ggagttgcga ttccgcatgg
     1921 cgaccattac cactttattc cttacagcaa gctttctgcc ttagaagaaa agattgctag
     1981 aatggtgcct atcagtggaa ctggttctac agtttctaca aatgcaaaac ctaatgaagt
     2041 agtgtctagt ctaggcagtc tttcaagcaa tccttcttct ttaacgacaa gtaaggagct
     2101 ctcttcagca tctgatggtt atatttttaa tccaaaagat atcgttgaag aaacggctac
     2161 agcttatatt gtaagacatg gtgatcattt ccattacatt ccaaaatcaa atcaaattgg
     2221 gcaaccgact cttccaaaca atagtctagc aacaccttct ccatctcttc caatcaatcc
     2281 aggaacttca catgagaaac atgaagaaga tggatacgga tttgatgcta atcgtattat
     2341 cgctgaagat gaatcaggtt ttgtcatgag tcacggagac cacaatcatt atttcttcaa
     2401 gaaggacttg acagaagagc aaattaaggc tgcgcaaaaa catttagagg aagttaaaac
     2461 tagtcataat ggattagatt ctttgtcatc tcatgaacag gattatccaa gtaatgccaa
     2521 agaaatgaaa gatttagata aaaaaatcga agaaaaaatt gctggcatta tgaaacaata
     2581 tggtgtcaaa cgtgaaagta ttgtcgtgaa taaagaaaaa aatgcgatta tttatccgca
     2641 tggagatcac catcatgcag atccgattga tgaacataaa ccggttggaa ttggtcattc
     2701 tcacagtaac tatgaactgt ttaaacccga agaaggagtt gctaaaaaag aagggaataa
     2761 agtttatact ggagaagaat taacgaatgt tgttaatttg ttaaaaaata gtacgtttaa
     2821 taatcaaaac tttactctag ccaatggtca aaaacgcgtt tcttttagtt ttccgcctga
     2881 attggagaaa aaattaggta tcaatatgct agtaaaatta ataacaccag atggaaaagt
     2941 attggagaaa gtatctggta aagtatttgg agaaggagta gggaatattg caaactttga
     3001 attagatcaa ccttatttac caggacaaac atttaagtat actatcgctt caaaagatta
     3061 tccagaagta agttatgatg gtacatttac agttccaacc tctttagctt acaaaatggc
     3121 cagtcaaacg attttctatc ctttccatgc aggggatact tatttaagag tgaaccctca
     3181 atttgcagtg cctaaaggaa ctgatgcttt agtcagagtg tttgatgaat ttcatggaaa
     3241 tgcttattta gaaaataact ataaagttgg tgaaatcaaa ttaccgattc cgaaattaaa
     3301 ccaaggaaca accagaacgg ccggaaataa aattcctgta accttcatgg caaatgctta
     3361 tttggacaat caatcgactt atattgtgga agtacctatc ttggaaaaag aaaatcaaac
     3421 tgataaacca agtattctac cacaatttaa aaggaataaa gcacaagaaa actcaaaact
     3481 tgatgaaaag gtagaagaac caaagactag tgagaaggta gaaaaagaaa aactttctga
     3541 aactgggaat agtactagta attcaacgtt agaagaagtt cctacagtgg atcctgtaca
     3601 agaaaaagta gcaaaatttg ctgaaagtta tgggatgaag ctagaaaatg tcttgtttaa
     3661 tatggacgga acaattgaat tatatttacc atcgggagaa gtcattaaaa agaatatggc
     3721 agattttaca ggagaagcac ctcaaggaaa tggtgaaaat aaaccatctg aaaatggaaa
     3781 agtatctact ggaacagttg agaaccaacc aacagaaaat aaaccagcag attctttacc
     3841 agaggcacca aacgaaaaac ctgtaaaacc agaaaactca acggataatg gaatgttgaa
     3901 tccagaaggg aatgtgggga gtgaccctat gttagatcca gcattagagg aagctccagc
     3961 agtagatcct gtacaagaaa aattagaaaa atttacagct agttacggat taggcttaga
     4021 tagtgttata ttcaatatgg atggaacgat tgaattaaga ttgccaagtg gagaagtgat
     4081 aaaaaagaat ttatctgatc tcatagcgta aggaatagca gtagaaaaag tctgaatcaa
     4141 aaatgaagtt ctctcaaaag ttagaaataa aactctgact ttgggagaat ttcattttat
     4201 tattaatata taaaatttct tgacatacaa cttaaaaaga ggt
//
LOCUS       DAVHSL010000095         4185 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000095 DAVHSL010000000
VERSION     DAVHSL010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.097"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            389..616
                     /locus_tag="VVR39_002132"
     CDS             389..616
                     /locus_tag="VVR39_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031520.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            904..3801
                     /gene="nanA"
                     /locus_tag="VVR39_002133"
     CDS             904..3801
                     /gene="nanA"
                     /locus_tag="VVR39_002133"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU6031521.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAVLTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1423 a          684 c          910 g         1168 t
ORIGIN      
        1 gtgttttgag ctgacttcgt cagtcttatc taccacctca aaacagtgtt ttgagcatca
       61 tgcggctagc ttcttagttt gctctttgat tttcattgag tataaaaaca gatgagtttc
      121 tgttttcttt ttatggacta taaatgttca gctgaaacta ctttcaagga cattattata
      181 taaaagaatt ttttgaaact aaaatctact atattacact atattgaaag cgttttaaaa
      241 atgaggtata ataaatttac taacacttat aaaaagtgat agaatctatc tttatgtata
      301 tttaaagata gattgctgta aaaatagtag tagctatgcg aaataacaga tagagagaag
      361 ggattgaagc ttagaaaagg ggaataatat gatatttaag gcattcaaga caaaaaagca
      421 gagaaaaaga caagttgaac tacttttgac agtttttttc gacagttttc tgattgattt
      481 atttcttcac ttatttggga ttgttccctt taagctggat aagattctga ttgtgagctt
      541 gattatattt cccattattt ctacaagtat ttatgcttat gaaaagctat ttgaaaaagt
      601 gttcgataag gattgagcag gaagtatggt gtaaatagca taggctgatg tccatcattt
      661 gcttataaag agatatttta gtttaattgc agcggtgtcc tggtagataa actagattgg
      721 caggagtctg attggagaaa ggagagggga aatttggcac caatttgaga tagtttgttt
      781 agttcatttt tgtcatttaa atgaactgta gtaaaagaaa gttaataaaa gacaaactaa
      841 gtgcattttc tggagtaaat gtcttatttc agaaatcggg atatagatat agagaggatc
      901 agtatgaatc ggagtgttca agaacgtaag tgtcgttata gcattaggaa actatcggta
      961 ggagcggttt ctatgattgt aggagcagtg gtatttggaa cgtctcctgt tttagctcaa
     1021 gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac tttcggggga gagctcaacc
     1081 ctaactgata cagaaaagag ccagccttct tcagagactg aactttctgg caataagcaa
     1141 gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa gagattacta tgcacgagat
     1201 ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg aaaccaatgc ttcaaatggt
     1261 cagagagttg atttatcaag tgaactagat aaactaaaga aacttgaaaa cgcaacagtt
     1321 cacatggagt ttaagccaga tgccaaggct ccagcattct ataatctctt ttctgtgtca
     1381 agtgctacta aaaaagatga gtacttcact atggcagttt acaataatac tgctactcta
     1441 gaggggcgtg gttcggatgg gaaacagttt tacaataatt acaacgatgc acccttaaaa
     1501 gttaaaccag gtcagtggaa ttctgtgact ttcacagttg aaaaaccgac agcagaattg
     1561 ccaaatggtc gagttcgcct ctacgtaaac ggggtattat ctcgaacaag tctgaaatct
     1621 ggcaatttca ttaaagatat gccagatgta acgcatgtgc aaatcggagc aaccaagcgt
     1681 gccaacaata cggtttgggg gtcaaatcta cagattcgga atctcactgt gtataatcgt
     1741 gctttaacac cagaagaggt acaaaaacgt agtcaacttt ttaaacgctc agatttagaa
     1801 aaaaaactac ctgaaggagc ggttttaaca gagaaaacgg acatattcga aagcgggcgt
     1861 aacggtaaac caaataaaga tggaatcaag agttatcgta ttccagcact tctcaagaca
     1921 gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc tccattcgag tgactggggt
     1981 gatatcggta tggtcatcag acgtagtgaa gataatggta aaacttgggg tgaccgagta
     2041 accattacca acttacgtga caatccaaaa gcttctgacc catcgatcgg ttcaccagtg
     2101 aatatcgata tggtgttggt tcaagatcct gaaaccaaac gaatcttttc tatctatgac
     2161 atgttcccag aagggaaggg aatctttgga atgtcttcac aaaaagaaga agcctacaaa
     2221 aaaatcgatg gaaaaaccta tcaaatcctc tatcgtgaag gagaaaaggg agcttatacc
     2281 attcgagaaa atggtactgt ctatacacca gatggtaagg cgacagacta tcgcgttgtt
     2341 gtagatcctg ttaaaccagc ctatagcgac aagggtgatc tatacaaggg tgaccaatta
     2401 ctaggaaata tctacttcac aacaaacaaa acttctccat ttagaattgc caaggatagc
     2461 tatctatgga tgtcctacag tgatgacgac gggaagacat ggtcagcgcc tcaagatatt
     2521 actccgatgg tcaaagccga ttggatgaaa ttcttgggtg taggtcctgg aacaggaatt
     2581 gtacttcgga atgggcctca caagggacgg attttgatac cggtttatac gactaataat
     2641 gtatctcact taaatggctc gcaatcttct cgtgtcatct attcagatga tcatggaaaa
     2701 acttggcatg ctggagaagc ggtcaacgat aaccgtcagg tagacggtca aaagatccac
     2761 tcttctacga tgaacaatga acgtgcgcaa aatacagaat caacggtggt acaactaaac
     2821 aatggagatg ttaaactctt tatgcgtggt ttgactggag atcttcaggt tgctacaagt
     2881 aaagacggag gagtgacttg ggagaaggat atcaaacgtt atccacaggt taaagatgtc
     2941 tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa aagaatacat catcctcagt
     3001 aatgcaggtg gaccgaaacg tgaaaatggg atggtccact tggcacgtgt cgaagaaaat
     3061 ggtgagttga cttggctcaa acacaatcca attcaaaaag gagagtttgc ctataattcg
     3121 ctccaagaat taggaaatgg ggagtatggc atcttgtatg aacatactga aaaaggacaa
     3181 aatgcctata ccctatcatt tagaaaattt aattgggaat ttttgagcaa agatctgatt
     3241 tctcctaccg aagcgaaagt gaagcgaact agagagatgg gcaaaggaga gatgggcaaa
     3301 ggagttattg gcttggagtt cgactcagaa gtattggtca acaaggctcc aacccttcaa
     3361 ttggcaaatg gtaaaacagc gactttccta acccagtatg atagcaagac cttgttgttt
     3421 gcagtagata aggaagatat cggacaggaa attattggta tagctaaagg aagcatcgaa
     3481 agtatgcata atcttcctgt aaatctagca ggtgccagag ttcctggcgg agtaaatggt
     3541 agcaaagcag cggtgcatga agttccagaa tttacagggg gagttaatgg tacagagcca
     3601 gctgttcatg aaatcgcaga gtataaggga tctgattcgc ttgtaactct tactacaaaa
     3661 gaagattata cttacaaagc tcctcttgct cagcaggcac ttcctgaaac aggaaacaag
     3721 gagagtgacc tcctagcttc actaggacta acagctttct tccttggtct gtttacgcta
     3781 gggaaaaaga gagaacaata agagaagaat tctaaacatt tgattttgta aaaatagaag
     3841 gagatagcag gttttcaagc ctgctatctt tttttgatga cattcaagct gatacgaaat
     3901 cataagaggt ctgaaactac tttcagagta gtctgttcta taaaatatag tagattgaaa
     3961 taagatgtga acaactctat caggaaagtc aaattaattt atagaaaaat tttagcagtc
     4021 aaggtgtact gttatagatt caatatatta tgcgactatt aaccttgtct tctcctaaaa
     4081 ttgactttct tgttttctta tcttgtccac tcgaaacaag tattgtaaga atttgattat
     4141 ttttgaaagt acttttaata tacttgatat agttaaaaaa gattt
//
LOCUS       DAVHSL010000096         3530 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000096 DAVHSL010000000
VERSION     DAVHSL010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.098"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..983
                     /locus_tag="VVR39_002134"
     CDS             <1..983
                     /locus_tag="VVR39_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031522.1"
                     /translation="KKTKKRNADSYFKQVESALNQLKSSVQNTDLIKMDIENGKLKHL
                     IGNLEFFTDDFLTKVNLFVRDEITDKEDEVYKELLNIISDSIGDVYEQEWIYEIEKEG
                     EKRFAEAIPPGFNDENKDGIRKYNGISYHQKYGDLIIWKDILKKATEQPRGDKVIFIT
                     NDGESNKKSDLIYKTSNMKVGPSIFLMNELYMCSRKKLYILNNTTLVNMITELSEDEI
                     DRIEAQEEKKYVVTFPKWILDKAEKDVRARNESNNSSVVYYIDSENRLASIDIDEVEP
                     LELISLLENPDVKKMLKEEILKKMLDGYYSKLPRHIIKDIINSYQEKNIQ"
     gene            complement(1538..1939)
                     /locus_tag="VVR39_002135"
     CDS             complement(1538..1939)
                     /locus_tag="VVR39_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6031523.1"
                     /translation="MLFFSISNDLLQLLISWEKQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISKALT
                     HSDTGTTQIYVNTSNVVPMTVGEFALKSLKQ"
     gene            complement(2315..3523)
                     /locus_tag="VVR39_002136"
     CDS             complement(2315..3523)
                     /locus_tag="VVR39_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6031524.1"
                     /translation="MNYIKRPHYLDFLRRHRDRPIIKVVSGVRRAGKSVLFQLYKEEL
                     LATGVDEDQIISINFEDLSYYDLRHFQTLFAYIKDQLVSKKTYYIFLDEIQHVEKFEL
                     VADSLFILANVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYAEKIDYLRGIYNSILLNDIVTRLGNPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDHKEDIGHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLEAIKDQFPKYLLTMDTIQPTANYNGIEK
                     KNIIDWLLEK"
BASE COUNT         1221 a          485 c          621 g         1203 t
ORIGIN      
        1 aaaagaaaac taaaaagaga aatgcagact catactttaa acaagttgaa tctgcattga
       61 atcaattaaa atcaagtgta cagaatactg atttaattaa aatggatatt gagaatggta
      121 aactaaaaca tttgattggg aatttggagt tttttactga tgattttttg actaaggtga
      181 atttatttgt aagagatgaa attactgata aagaagatga agtttataaa gagttactta
      241 atattatttc tgattctatt ggagatgtgt atgagcagga atggatatat gaaatagaaa
      301 aagaaggaga aaaacgtttt gcagaagcta ttccaccggg atttaatgac gaaaataaag
      361 atggaataag aaaatataat ggcatatctt atcatcaaaa atatggtgat ttaattattt
      421 ggaaggatat attaaaaaaa gcaacggaac aacctcgtgg tgataaagtt atctttatta
      481 ctaatgacgg agaatcaaat aaaaaaagtg atttaattta taaaacttca aatatgaaag
      541 ttggtccaag tattttcttg atgaatgaat tatatatgtg tagtagaaaa aaattatata
      601 tattaaacaa tactacactc gtaaacatga ttacagagtt atcagaagat gaaattgata
      661 ggatagaggc ccaggaagaa aagaagtatg ttgttacgtt tccaaaatgg attttagata
      721 aagcagaaaa agatgtgcga gcaagaaatg agtcaaataa ctcgagtgtt gtatattata
      781 ttgattcaga aaataggtta gctagcattg atattgatga agttgaaccg cttgaactca
      841 tatccctgct agagaatcct gatgtaaaaa aaatgttaaa agaagaaatt ttgaagaaaa
      901 tgttagatgg ttattacagt aaattaccaa gacatattat taaagacata ataaatagtt
      961 atcaagaaaa aaatattcaa tgaatttaat aataaaattt catcatttag ggcaaattac
     1021 tgataaagct gactcgtttt ggttggtttt gtagaaaaat ttgccctatt tagatgaaaa
     1081 tggttgaaat tagttgagaa ctagtaaata tttggtagtt aaaaatggtt tgattaaagg
     1141 taattgaaag aacttagtta ttaggttagc caaaccaggt cttaagaaag ctcgtaaagc
     1201 atcacaattt agtaagcgtt aattcgaaag aattactata cttatacaga gcacctttcg
     1261 gggtgttctt tttttatact ttcttactaa attggtgtaa ttgacacagt tgttgcgact
     1321 ttagtcgctt acaaatgtgg ctgcaacctg acaaggtcag ttgcctcaaa acgttaatca
     1381 atacgattat atcaacgttt caaagcactc aaaagttcac cttattttta tagtaaaatg
     1441 aaataagaat aggacaaatc gatcaggaca gtcaaatcga attctaacaa tgttttagaa
     1501 gtagaggtgt actattctag tttcaatcta ctatacctta ttgttttaga gactttaaag
     1561 caaattcacc tactgtcata ggaactacat tagaagtatt tacataaatc tgtgttgttc
     1621 ctgtgtcact gtgtgttaga gccttagaaa tggcttctaa gctcattcct gcttttttag
     1681 caagtgtcgc tcctgtatgg cgtaatttgt gaggtgtagc gtgtgtcagt tctttatgtc
     1741 gctttctaat gcttttcatt ttattgttca gatagtcggc atgtaaaggc ttgttgatgt
     1801 ttccttttgt gtcgatatat gtaaaaacaa attgttctgg attactgagg atgccaaact
     1861 ttgctagttc atatctttgt tgtttttccc aagagataag aagttgaagt aaatcattag
     1921 aaatagagaa aaataggata gcaaaagctc tatttcagga gaaaatgaag caaatatttc
     1981 cataataaaa cgcatattat caaggttgtt caatacctga tactatgcgc ttttctgatt
     2041 ttaaagactg attgctcagt ctctttttca ttataattca gttacaattt aatcttattt
     2101 gagaaagtgg gtgatgctat tctctaataa gactatgata ttaatttttg atagtacttc
     2161 cagaaattat agatcccctt tcatccccaa tttctatttt caagtgtccg tattatatag
     2221 cgtattcgaa attcactata tcttgttagg atttggggag aatcattggt aacagactgt
     2281 tgcaaatcta attagctgta tgatttatat ttatctattt ttctagtaac caatctataa
     2341 tgtttttctt ctcgattcca ttgtaattgg ctgttggctg aatcgtatcc attgttaata
     2401 gatatttagg gaattgatct ttaatggctt ctagtggtct aagttctctt tctagtgttt
     2461 ctggagcaag tgttgtttca ctgacctgat aataagcgta gtggccaaga tcagttacaa
     2521 caacaaaatc aacctcatac ttatctaaat taccaacata tacttgtgaa tatctacgtc
     2581 tcaattccaa atataccata ttttccaaga tatgcccaat gtcttctttg tggtctggta
     2641 ataagagatg tcgtaaacct aaatcaacgg gataatattt ttctaagcgt tgcaataatg
     2701 ctctaccttt tacatcaaaa cgtggaacgg aataaaaaag taaactatct gtcaaagttg
     2761 tcaaataatt ttccaaagta ttatgggata ttgaaacatt ttggctgact agggtattgc
     2821 gaatcttatt tgttgatatt aagctacctg tactactgag aagggttcgg acaatgcgct
     2881 caataatagt aggatttgga tttcccaatc tagtgacaat atcatttaac agtatggagt
     2941 tatatattcc tctgagatag tcaatttttt cagcgtaaga tgatgtttgc aataagtaag
     3001 ggaaagcact aaagagataa ttgttaaaaa tttctgttgt attcagattc tctgtgagag
     3061 attgacctga tagatattct tcaaatgaca aaggaagaac ctctatctca acataccgac
     3121 cagtcaagtt tgttgctaat tggctactca taaagtaggc gttagatcca gtcaaataga
     3181 ggtctacatt tgctaagatg aatagactat ctgctaccag ttcaaatttt tcaacatgtt
     3241 gaatttcatc taaaaagata tagtatgttt tcttgctaac taattgatct tttatataag
     3301 cgaataatgt ttgaaaatgt cgcagatcat agtaactcaa atcttcgaaa ttgatggata
     3361 taatctgatc ctcgtctacc ccagttgcta gtaactcctc tttatagagt tgaaaaagca
     3421 cagatttacc agctcgtcta actccactca caactttgat gattggtcgg tcacgatgtc
     3481 ttcttaaaaa atctaaataa tgtggtcttt tgatatagtt cataatagtt
//
LOCUS       DAVHSL010000097         3369 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000097 DAVHSL010000000
VERSION     DAVHSL010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3369
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.099"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..132)
                     /locus_tag="VVR39_002137"
     CDS             complement(<1..132)
                     /locus_tag="VVR39_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6031525.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     "
     gene            complement(317..928)
                     /gene="rpsD"
                     /locus_tag="VVR39_002138"
     CDS             complement(317..928)
                     /gene="rpsD"
                     /locus_tag="VVR39_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU6031526.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1123..2175)
                     /locus_tag="VVR39_002139"
     CDS             complement(1123..2175)
                     /locus_tag="VVR39_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6031527.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2172..2870)
                     /locus_tag="VVR39_002140"
     CDS             complement(2172..2870)
                     /locus_tag="VVR39_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6031528.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLLPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3037..>3369)
                     /locus_tag="VVR39_002141"
     CDS             complement(3037..>3369)
                     /locus_tag="VVR39_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6031529.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT          947 a          754 c          639 g         1029 t
ORIGIN      
        1 tttctctttt agctttaacc agccataaat ggtattacgt gagatttgga aaacgtgtga
       61 tgcttctgtt atactacctg ttcgctcaca ataagagaga acttttttac gaaaatctat
      121 tgaatatgcc ataaaagatt ataccacatt gtgtactatt tttggttcat tttactatat
      181 cactttggac tatatcggtc tagttatgtc tcaacgatta tagctggata ctaagagaaa
      241 tcaaaaaagc actaagggag aacgtcccaa agtgcttaat atcaaggcct caaagcctgt
      301 cttattcaat aaaatattac aacatcttgt tgtagaattc aacgacaagt gcttcgttga
      361 tttctgggtt gatttcgtcg cgttctggca agcgagtcaa tgaaccttcc aacttttcag
      421 cgtcgaatga tacgaatgct ggacgtccaa gagtagcttc tactgcttca aggattgctg
      481 gaactttcaa tgatttttca cgaactgaga tcacttgacc tggagttacg cggtatgatg
      541 ggatatcaac gcgtttcccg tcaacaagga tgtgaccgtg gtttacgaat tgacgagctt
      601 gacgacgagt agtcgcgaga ccaagacggt aaacaacatt atccaaacga cgttccaaaa
      661 gaagcataaa gttgaaacct aggattccac ctttgatttt tgtagcttgt acgaacaagt
      721 tacggaattg tttttcacct acaccgtaag tgaaacgaag tttttgtttt tcagccaatt
      781 gcaaaccata ttctgacaat ttagaacggt tgtttggtcc gtgttgtcct ggtacgtagt
      841 tacgacgtgc caattcttta cctgtacctg taagtgaaag gccaaggcga cgagcttgtt
      901 tccaagatgg tcctgtataa cgtgacatat gaatgtcctc ctgatataaa taatatttcg
      961 gtggaaatag tcacttagaa agccctgatt cgtgcagatg cccttcgcct aaacagccaa
     1021 ggttacttgt cataagacac ctgttgacga gcttcatgct ttcctgctga tatttcacac
     1081 aaaatccatt ttaccatgaa tagctggatt tgtaaaggag ttttaggctt tattttcact
     1141 accagagaga ttgagaacga gggtaaaggt acttcctaga ccgtactggc tgctgactgt
     1201 gatttcccca cccaattgat gggccaattc acgcgcaatc gcaagtccta atccatggcc
     1261 acctgtcttc atgttacgcg aagtttcgac acgataaagg cgtttgaaaa tattttccaa
     1321 atcctctggg gcaatgccct gcccttcatc ggtcacactg attgaaagct ggcccttctc
     1381 cagcttagtc accacttcca gcttggttcc tggagcagaa tatttaaaag cgttatcgac
     1441 cagattcacc aagatacgag aaagcttagc ataatctccc tcaatccggg cagactctgg
     1501 gattacttgc aagtggacat ctcttctctc ctgctcaatc aaaaactgaa attcactcat
     1561 gcactcaatt aagagcttgt ccagaaaaat actgtcttta ctggtagttt ccacctgatt
     1621 tctagctgta tttagggtca aaaaattcaa ctcctcaacc agtttattga gcctctccgt
     1681 ctggcgtcca atggttgcta gataatgagc ttgctccgac tccttgataa tcccatccaa
     1741 aatcccttct accgtcgctt gaatcgaagt gataggggtc ttaatatcat gcgacaactg
     1801 ggcaatcatc aagccctttt ctcgttcgct ttcttccaag gaatcaaagc ttacctgcaa
     1861 atcatgggac atctcattaa aagtttgccc taattgctga aattctacag gaccttgaac
     1921 ctccaaattt gaaggaaaat ccttggccgc tacccgcttg gcatgctcct tgagtttgcc
     1981 caacgacgta aagactggca ataggagaaa gagactaatc ccagcaccga caaggctggc
     2041 aacgatggtc atcccaagca aaaagtaaat ctcgcctttc gcaatcagca ttttttgaac
     2101 agcccaaaaa acaaccaaaa tggttaagag ggttgaaata atatatccaa ccaaaatata
     2161 actttttagt ttcatgtttg tcctctcggt ttctctatct tatatcccaa cccccaaact
     2221 gtcttaatag tgggcgtttg gtcactacta tattttgcca gctcctgtcg aagagcatgg
     2281 atatgcacat tcaaggtatt ggtgtcatcc acgtagtctt ctttccagat cttttcatag
     2341 aggtctgtct tggagaaaac tcgctctgga ttgctagcta aaatccacag caattcaaat
     2401 gatttaacag ttaaatccag catttcttct cctatttgaa cttcatgact actatgattc
     2461 atttttagat tgccaaggga aatcagctct gtttcgcccc cacgatgaag gcggcgcaaa
     2521 atattgtgga cacgcaaaac tagctcacgt gggctaaaag gcttagcaat aaaatcatct
     2581 gctcccaagc tcaggccgta aatcttgtcc tgttcactgg tcttagcagt aataaatagg
     2641 aaaggctgct ctggtaataa gtattgaacc tcactgatta aatcataacc atccatccga
     2701 ggcatcatga catctgtgat aatcaaatca atcggttttt tcttgaacag ctctagcgct
     2761 tccagtccat catgggctac caagacctga taacctgcct gaattaagta tctctgatga
     2821 atatctgtga tttctacctc gtcgtcaacg agtaaaattg tctttcccat ctgtctctcc
     2881 tttgataaaa acagtgctat actgctttaa gtataacact atttttattg ttttacgatg
     2941 attttaatct gctattgaaa gaaagtcctg attgctgatt gagttgttaa actaatctta
     3001 gtcagcccac tatccatcat ttatttcctt agctgattag ttttcttctt ttttgttttt
     3061 caaacctaga ccaccgagta aacctgcaag cgcaagccca aggaaaccaa tacttgccat
     3121 tgatgtttga gtctcaccag tatttggtag catagcttta tcctctgaca tcatcgtatc
     3181 agacatcttg ttagcagaag cagccatgtt ttcacctgcc atcgtgttgg tagaacttgt
     3241 catggtgtca gcaggcatgc tatctgtagt acctgtagca tgattgtgat tcatcggagt
     3301 cacgccagaa ccagagttag aaggtgataa tgaaccattt gctgtgtctg atgtttcttt
     3361 aacatttat
//
LOCUS       DAVHSL010000098         3360 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.100, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000098 DAVHSL010000000
VERSION     DAVHSL010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.100"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            158..640
                     /locus_tag="VVR39_002142"
     CDS             158..640
                     /locus_tag="VVR39_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009431600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEU6031530.1"
                     /translation="MEDVEKKILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDID
                     QYKVVSGKLKKLLSDKEKLSPKKWNEEKILLMSNLEEINKEKDKIKDEYQEINHIKYS
                     VDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYREMMKNKKMDQER
                     "
     gene            714..887
                     /locus_tag="VVR39_002143"
     CDS             714..887
                     /locus_tag="VVR39_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031531.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNI
                     KNYLSDKRTHINY"
     gene            1073..1609
                     /locus_tag="VVR39_002144"
     CDS             1073..1609
                     /locus_tag="VVR39_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU6031532.1"
                     /translation="MINEEISKEAGQAAQTAQTIISYTIKETKESINLEKEIRKKMNE
                     TLEKANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNK
                     ESKNYEIFFQAKDIKVMEYAFKQVISKENKKEKESILKQIKKYKDLSKNKDKTKEKGK
                     RKVKEKVKPNKKDMTREI"
     gene            1736..2456
                     /locus_tag="VVR39_002145"
                     /pseudo
     CDS             1736..2456
                     /locus_tag="VVR39_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
     gene            3140..3301
                     /locus_tag="VVR39_002146"
     CDS             3140..3301
                     /locus_tag="VVR39_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031533.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDQTPAKNQEMKNSFD
                     MAKTQIETD"
BASE COUNT         1619 a          430 c          556 g          755 t
ORIGIN      
        1 taataaagaa aaatatgact tcaaaaagct aacaagtgca tatagttatt taagaaaaaa
       61 caacatagaa accataggtc agttacaaac aaaaatagaa actttaaagt ctaatagtta
      121 taggctaaat agaaaagcaa agacaatcca taaagaaatg gaagatgtag aaaagaaaat
      181 tctatactat gaaatctaca aagccaaaaa agaagtttat gaagaatatc aaaagaaaaa
      241 tatattcaca aaagaagcat tttataacaa acataagaaa gatatagacc aatataaagt
      301 agtaagtggg aaattaaaaa aactcctatc agataaggaa aaactaagtc ctaaaaagtg
      361 gaatgaagaa aaaattcttt taatgtcaaa tcttgaagaa ataaataaag aaaaagacaa
      421 gataaaagat gaataccagg aaattaatca tataaaatat tcagtagatt ttgtaaacaa
      481 agaacttggt atagatttat ccatagaaat agataagcta ataaaacagg gagaaaaacc
      541 aagtgtaata gcacagatta aaaagttcca agaccaagtc aataaagata atgaatacag
      601 agaaatgatg aaaaacaaga aaatggatca agaaagataa gacctggtaa aaatatctta
      661 tccaagctat aatatgacca aacaactaaa gtcagatcta ggaggtaata gagatgaata
      721 aaaggcaaga gctaatagat gaactcataa aagcaaatga agatggaaca tacaaaacct
      781 ataaaagcac agaagaaata aaagcaatga acaatgaaga aatacagatt atatattcca
      841 acataaaaaa ctatctatca gacaaaagaa cacacataaa ctattaaagg tggaaaggta
      901 gtgtaagcta tttttaaaag tataaaaggt acaaagacct aagaaatata taaaaacatc
      961 aaaataaagt attccaccac caagaacaat aaaataaaaa caagcaaagg gaagtataga
     1021 aaaattaaaa cctatacttc ccttttttaa ttcaaacaaa ggagagaaaa gcatgataaa
     1081 cgaagaaata agcaaggaag caggtcaagc agcacaaaca gcacaaacca taatatcata
     1141 cacaataaag gaaacaaaag aatcaatcaa tttagaaaaa gaaataagaa aaaagatgaa
     1201 tgaaacttta gaaaaagcaa atggaaactt aaaaagtctt atgggcgatg aaatgaaaat
     1261 aaaagacctc tacaagaaag gacaactaga aaatataagc atagatcaaa tcgacctcaa
     1321 agacttaaaa aaagaactaa acaaacttgg agtaagtttc tcagtaatga aaaacaaaga
     1381 aagcaaaaac tatgaaatat tcttccaagc caaagacata aaagtaatgg aatatgcctt
     1441 taagcaagtc atatccaagg aaaataaaaa agaaaaagaa agtatcctaa aacaaataaa
     1501 gaaatacaaa gacctatcca aaaacaaaga taagacaaaa gaaaaaggaa aaaggaaagt
     1561 aaaagaaaaa gtaaaaccaa acaaaaaaga tatgaccaga gaaatctaaa gggagtaacg
     1621 aaaagttaca cccttaaata accataataa caagacttcc gaaaaacaga agtccagaat
     1681 tccgaaaatc ggaaatcaag aatttcgatt atcgaaaatc aagaaaggag cagatatggc
     1741 aacaaacaaa agatactatt ggataaaatt aaaagaagaa tttttcacag acaaaaggat
     1801 aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc taaaacttct
     1861 actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa gtgattttat
     1921 aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa cagtaaatta
     1981 tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact acctaactga
     2041 aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa gatacagaca
     2101 aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag agatagagaa
     2161 agatatagag atagataaag agagagggag agatagataa aaagtccacc cccatttttt
     2221 atggagaatt caaaaatgta aggttaagca aagaagaata taaaaatcta aaagaaaaat
     2281 taaactcaca cacagatata atgataaata aactatccag atacatggaa agcagtggta
     2341 agacctatca aaatcactat gtgacaatct taaaatggta tgaagaagat aaagacaaac
     2401 taagacagaa aggtttaaat aaaaaaatga attatgatgt aggagaatct ttatagataa
     2461 aaagaggtgg aaaggcacta ttaaagactt taagtctaaa aaggtatcaa agtatgccag
     2521 agataaaaaa atataaatat gacactttaa aggcgattag aaaattaaag aaatgctaga
     2581 agacttttag atgacagtta ccaagagggt ctaattttca ctgctactta tgcagtggga
     2641 attggacctt tttatataag caaattctat ttcaaaattg gttaccaaga aagacttctt
     2701 ttcactgtta agtataagag ggtaatttat agaattttgt tacatcaaga taaatatttt
     2761 ctgatggtca aattttaaaa agattaataa ctctcgataa attttgaacc ttaacaattg
     2821 aatagaccaa gacaagacgt taattatttt tggagcgtaa taacctatcc gtcaagatct
     2881 ttcggctgaa taattcggca aaaaaagttc tgctaagcaa aaagaaagtg agcgataagt
     2941 aagagtttga atataggaag ggatacccta tccgctatga agaaaatgag gataatgata
     3001 cttctaaggt tgaagccggc tcatccggaa tagaggcgga ggtgagattc ctatgttgct
     3061 aatccaaagc acttgtcaat gtcaaaaaac ttaattaaac aaataattat tagatataaa
     3121 actttagagg aggtatatat tggacaatga ctggaatgga ttggctgatt taatagcaaa
     3181 tctgattgca aaatatgctg gtgctttaga tttagataat ctacccgatc aaacgccagc
     3241 aaaaaatcaa gagatgaaaa atagttttga catggcaaaa acacaaattg agacggacta
     3301 ataaaagtgt tataatatac ttgaaatgat agtccaaact taaattaaaa aaattatata
//
LOCUS       DAVHSL010000099         3295 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000099 DAVHSL010000000
VERSION     DAVHSL010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.101"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..652
                     /locus_tag="VVR39_002147"
                     /pseudo
     CDS             1..652
                     /locus_tag="VVR39_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            624..1268
                     /locus_tag="VVR39_002148"
     CDS             624..1268
                     /locus_tag="VVR39_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU6031534.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSQEKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1310..>3295)
                     /locus_tag="VVR39_002149"
     CDS             complement(1310..>3295)
                     /locus_tag="VVR39_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6031535.1"
                     /translation="FRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNPK
                     IAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHLI
                     SMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLLV
                     FGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLALT
                     VKDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLIF
                     RMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDLD
                     KLLSQFASDKGYKIKEKEVLRYTYFAVTNQEGTKLTIFEKGQNRVQPKTVFMVFDQKD
                     YENMTGQKLSLSGNEVGLFVKNDGLKGQKTLTLNDHQFSVKEEFNKDFIVNHVPNKFN
                     ILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQFN
                     AQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGYE
                     DRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGVL
                     DTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
BASE COUNT         1035 a          651 c          668 g          941 t
ORIGIN      
        1 aagcaagcag gatctgcttt accctagaaa aggaaaagcg cttaagaaac aggctagcac
       61 caactttaaa cctgctggtc aatccatcga acagcggcct gaagctatca atcttcgctt
      121 ggagaatggg cattatgaga ttgatacggt tctacttacg agatcgaaaa actactgctt
      181 gcttgtcttg acggatcgaa agagtagaca tcagatcatc cgattgattc caaataaaag
      241 tgctgaggtg gtcaatcagg ctctaaaact catcttaaaa caacacaaga ttctttccat
      301 cacggcagat aatggaacgg aattcaatcg cttgtttgat atattttctg aggagcacat
      361 ctattatgcg cacccctatg cctcttggga aaggggaact aatgagaatc acaacaggct
      421 cattcgtaga tagttaccta agggaaccaa gaaaatgact cccaaagaag tcgcattcat
      481 cgaaaagtgg attaacaact atcctaaaaa atgcttggac tacaagtcac ccagagaaga
      541 cttctggatg gctaacttga acttgaaatt tagcgtcaga aacaaatcac gaaatcgatt
      601 caaattttgc aggtcgttta aatatcctac gcgcaggtgt tcttggtgct aacgatggaa
      661 ttatttccat tgctggtgtg gttatcgggg ttgccagtgc cacgaccaat atctggatta
      721 tctttttatc aggatttgcg gctatcttag ctggtgcctt ttcaatggct ggtggagaat
      781 atgtatccgt ttcaactcca aaagataccg aggaagctgc cgtttcgcaa gaaaaactct
      841 tgttagacca agatagggaa ctagccaaaa aatccctcta tgctgcttat atccaaaatg
      901 gagaatgcaa aacttctgcc caactcttga ccaataagat ctttcttaaa aatccactca
      961 aggctctggt agaggaaaaa tatgggattg agtatgaaga atttaccaat ccttggcacg
     1021 ctgccatttc tagcttcgtt gcctttttcc ttagaagttt gcctccaatg ctgtcagtga
     1081 ccatattccc aagtgaatat cgcatccctg ctactgtcct tattgtcggt gtggcccttc
     1141 ttctcactgg ttacactagt gccagacttg gaaaggatcc gactagaaca gctatgattc
     1201 ggaaccttgc tattggtctc ttgaccatgg gagttacctt cctgctcgaa caacttttca
     1261 gcatttagaa tacaagaaat acctcgattt tgaagtcgag gtatcttttt tacatttgca
     1321 caatcttgcg ataacttctt gaagtaatca tgaaaatcag cacataggcg atgaggaaga
     1381 tagcgcagat agacaaggtc acaatcaaca tcatagtcgt atccagtaca ccaatcactt
     1441 ttaaaatcag gctaagcata tggtaggcaa aggcgagatg tatgaaggca aagagcaaag
     1501 gaaggaagaa aacagttaaa acctgtttgt tgatggtttg cttgatttgc ttttggtcca
     1561 aaccgacttt ctgcaagata ataaagcgtt cacggtcttc gtagccttca gaaatttgtt
     1621 tgtagtagat gaccagaaca gttccgacca taaagataat ggataggaaa ataccgataa
     1681 agaagacacc accaaagagg gcactcatct gagaactagc atctgctaga ttgctaccat
     1741 aaacatagct accttctgtg tctaattgag cattaaattg attgaggtag ttttcatact
     1801 cctcagcgac cttgagttgt tcttcttcgc tggcatctac attcatacca ccgtaaaact
     1861 gattatagat agccgaatct gggaattgat ccaaaaaggc ttgtaaatca ggaacaacaa
     1921 ggtaattgta atcagtagtc aagatattaa acttatttgg aacatggttg acaatgaaat
     1981 ctttattaaa ttcttctttg acagaaaatt gatgatcatt tagagttaga gttttctgtc
     2041 ctttcagtcc gtcatttttg acaaagagac cgacctcatt tcctgataga gacagttttt
     2101 gaccagtcat attttcataa tctttttggt caaataccat gaaaactgtt tttggttgga
     2161 cacggttttg tcctttttca aaaatagtta acttggttcc ttcttgattc gtaacagcaa
     2221 agtaagtgta acgaagcact tctttctctt taatcttata acctttgtca cttgcaaact
     2281 ggctcaagag tttgtccaaa tcttcttttt caacattttg ccctgaaacc ccaaaatcat
     2341 gaggatttag aactttttta aaggattctg cggaattgaa aatgcttgtc gctgctgaca
     2401 tggttaccaa aaccattgtt gacaaaatag cgatagttgc tagtccaact gcatttttct
     2461 tcatacggaa aatcaagtta gaaacagata tgagattatt aggttggtaa tagtatttct
     2521 tatttttctt taagatttga agaaaaacgg taatccctgc attgaacaaa agataagtac
     2581 caaagataac cagtaaaaca gctaggaaga aggttgttaa ggctgtaaga ggatctttta
     2641 ccgtaagggc aagataatat ccaatcccta aacttatgga accaagaata gtttggagag
     2701 gaaggaagcg accttttttc tctccgctag ctttctcacg tgagagctgg agggcattca
     2761 tacgggcgat tcgaagggca ttcaggaaca tgaggcctag gaaaatcaaa ccgaagacaa
     2821 gaagtactgt aatgacaact ttcatctgga aggtagcgac cagttccacc ttcaatttca
     2881 tcagtttgag taggaaagcg aaaatcaact tgtcaaacaa ggctccaata ccgattcctg
     2941 ctccaacagt tagaatccca aatagcacta actccttaaa ggtcatactg attagatggc
     3001 gcttctccaa gcctaacatg ccatatatac ccagttcctt ggaacggttt ttcatgacaa
     3061 aactattggc atagaggacg ataatggctg acgcaagggt aacgacaaac ataccaaatc
     3121 caagtgttgc ttgaatggtg gttcctccac gaatttccgc aatcttggga ttgaaggtta
     3181 gggagtaaaa gagataggtg atggtgactg ccaagagaac agccagtgca aagggatagt
     3241 agagtttgcg gtttttaatc aagttcgata ccgctaactt attggttaat cgaaa
//
LOCUS       DAVHSL010000100         3106 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000100 DAVHSL010000000
VERSION     DAVHSL010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.102"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..194
                     /locus_tag="VVR39_002150"
     CDS             <1..194
                     /locus_tag="VVR39_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6031536.1"
                     /translation="KGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTL
                     SSGVTLITGKNGTGKSTLL"
     gene            complement(560..1870)
                     /locus_tag="VVR39_002151"
     CDS             complement(560..1870)
                     /locus_tag="VVR39_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU6031537.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2107..2979
                     /locus_tag="VVR39_002152"
     CDS             2107..2979
                     /locus_tag="VVR39_002152"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU6031538.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          957 a          515 c          711 g          923 t
ORIGIN      
        1 tgaaggggaa agagtatgaa aacagaactg tttcttttgc tattagttca aaaggagaaa
       61 aaatgaaagt agaaaatatt tcgtataggg tggatcatcg tatattgttt gataatattt
      121 cttttgatac tttgagttca ggcgtgacat taattactgg taaaaatggt acaggaaagt
      181 caactttact atagtagatt gaaactagaa tagtacacat ctacttataa aatattgtta
      241 gaaatcgatt tgactatcct gatctatttg tcctggtctt atttcatttc actatatttc
      301 aaattgagta tgacgaagtg cgctcccatg tcctgggaac gcactttctt catatttttc
      361 atattcttga atccatcgat aaagactatt gggatgaatt tttaaagttg aactaatcat
      421 ttttacagga tgaggtttac agcagagagt ttgaaggctt tatcaaaggt ttttcttggc
      481 ataatgactt ttcctcgttt ccacttaatt ttgtgtctac tttattatac caagtccacc
      541 cttaagttag ataataaatc taacttaagg aagctagaag gatgagaatc caggtggtca
      601 agagtcccaa acttaagctg atggggacac ccagaataat ttgctttttg aaggcaaggc
      661 cacgttcctc tatattggga agtgagagtt gaatgagaga accagctgat gaaaagggtg
      721 agatattagt agatagagcg ccaataacgg tggctgttgt gagtaagtga atatcaatct
      781 gaggattttg agcactgatg atagcaatga tgggaaagag ggctggagct acaacggata
      841 gggtggaact aaagagtgac atcactccgg ctatcacaca aaagaacaga ggtaaccaga
      901 aatgaggaat ggttgttgtc atgaggtgcc ctatcagtgt gactaaacct gacttgaccg
      961 ctagagacat tagtaagctc atgccgcaga gcatgataat tgtagcccag ggaaccttag
     1021 ctaaaatggc ttcttgcttc cctaatttga gccttaaggc gaggcagacc atgagtattg
     1081 agacaaagcc aatatcaaat gttttttgat aagtagctat ccaggcgatg tttgggaaaa
     1141 tgagatgcaa caagggaaaa agccaaacca aaaccatgct gctgatcatg agcaaggtgg
     1201 tttgtctttg aaccttgctg aggagtggtg gttggtcaat agtcaaggat gagtttgttc
     1261 ttcccttact atagtgactg taacaggata ataaaagcaa gacgatgagt gggtagataa
     1321 tgctgacgat aaagatatga ttgccaagtg aaaaagcttg ctcttcccat cccatttgct
     1381 taaacaggcc ttgaaagaca atgcctgagc tactggttat caaattagcc cctcctgaag
     1441 ctccccaatt gacggcttga gctccaatca aagggtgttt gtccgctttt tgacagaggg
     1501 taatcgctag aggacagcaa acggccatag tagtgaaaaa tccagcacct aaagcagaca
     1561 aaagggttgc catcaggtat aaaatcatgt agagggcgtt agggtaggtg cgtgtgcggt
     1621 agagaatgtg ttgagccaaa acatcaagag taccgttagt tgttgcaacg ttataaaaga
     1681 gagagacgct aaaaatggta aaaaagagtg aggttggcca aaaatgaaga agttctttgg
     1741 ggcttaatcc catgagagtg gttgcgatga ggtaagaaaa agcaatagcc agcaggccaa
     1801 tattgatttt ggtgcggtaa ccaattccaa tggctagagc aatggcgcta atcattatta
     1861 aatgaatcat tgaattgtcc tttcagttag aatatggaaa taggttggca attttggcgc
     1921 tcaaaagacc acctgtttcc tattggtact tgactattat acacaaaaaa aatacaattg
     1981 tcttgacaat tgtattgaca cttgttagaa ttaaaaatga ggtattcagg cttgtgattt
     2041 cctatggaag ttaatagtga ttgcctctag tgcttacaag tgatattaaa aatagaggac
     2101 ttagtgatgt caatcatttc aactgattta accccttttc aaatagatga tacattgaaa
     2161 gcagccttgc gagaagatgt tcattccgaa gattacagta ccaatgccat ttttgatcat
     2221 catggccaag ccaaggtgtc gctttttgcc aaggaagctg gtgttttagc gggactaacc
     2281 gtttttcaaa gggtttttac cctatttgat gccgaggtga ccttccagaa tcctcatcaa
     2341 tttaaggatg gggatcgttt gactagtggc gatttggttt tagaaatcat aggctcggtg
     2401 agaagtctct taacatgtga acgcgttgcc ttgaattttt tacaacattt atcagggatt
     2461 gcttcgatga cagctgctta tgtagaagcc ttaggcgatg attgcattaa ggtatttgat
     2521 actcgaaaaa ctactcctaa tttacgtctt tttgagaaat atgccgtgag agttggcggt
     2581 ggctataatc atcgctttaa tttatcagat gctatcatgc taaaagacaa tcacattgcg
     2641 gcagtaggta gtgttcaaaa ggcaattgct caagcgcgtg cctatgcccc ttttgtgaaa
     2701 atggtcgagg tggaagtgga aagccttgct gctgccgaag aagctgcggc ggcgggtgct
     2761 gatattatca tgttggataa tatgtcattg gaacagattg aacaggccat taccctaatt
     2821 gcaggacgtt ctcggattga atgttctgga aatattgata tgaccactat tagccgtttt
     2881 cgtggtttag cgattgatta cgtctccagt ggtagtttaa cccatagtgc taagagtctt
     2941 gatttttcca tgaagggttt aacctacctt gatgtctaag ttgtaaaata aactaacttt
     3001 ttaaaggatg tctttcctct agaacgagtt ttatgtcaga tagtttaaac gcctcttcaa
     3061 atatagtaaa atgaaccaaa aatagtacac aatgtggtat aatctt
//
LOCUS       DAVHSL010000101         2846 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000101 DAVHSL010000000
VERSION     DAVHSL010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.103"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..314
                     /locus_tag="VVR39_002153"
     CDS             <1..314
                     /locus_tag="VVR39_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031539.1"
                     /translation="KKGQFDELVSNLNLSEQEQLDLLQQYKEEHPRRAKRGIKSAIIK
                     KVARFLAAKVGQKSVVEITDYLFEWQDNLEVGAENYLVQYGWDRNIAHWTIKTVSFIF
                     L"
     gene            801..1763
                     /locus_tag="VVR39_002154"
     CDS             801..1763
                     /locus_tag="VVR39_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEU6031540.1"
                     /translation="MEKWENQDKILLDKNKRGKDRNWRGRKLLSLKLADIFKELGYRE
                     TLIERVETCGDTLRFIRREDGSLRLYQAYFCKNKLCPMCNWRRSMKYSYQTSQIVDEA
                     IKEQPKGRFLFLTLTVKNVPGKELNATISQLTQSFDRLFRRAKVKKNLIGFLRSVEVT
                     HNQEEETYHPHIHVLMMVKSSYFSGAGDNYVSQEEWGRMWEQSLKVDYVPMVDIRSVK
                     EIGKGLKGAILETAKYPIKPIKLDVENKQVVGDLYNGLYRKRQLGYGGLFKEIRKRLQ
                     LSNVENGDLVYTSDDNDEMSKGTKIVAIWNATKQNYFVKNKGWN"
     gene            2684..>2846
                     /locus_tag="VVR39_002155"
     CDS             2684..>2846
                     /locus_tag="VVR39_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031541.1"
                     /translation="MNKKFLKCGTLFLISCSILGSTIPAVTVFSDEVTITYNSENNSE
                     KNELYNQLSA"
BASE COUNT          989 a          334 c          592 g          931 t
ORIGIN      
        1 aaaaaaaagg acagtttgat gagttggtaa gtaatttgaa tttgagcgaa caagaacaat
       61 tagacttgtt gcagcagtat aaagaggaac atcctcggcg agctaaaagg gggataaaat
      121 cagctataat aaaaaaagtc gctcgtttcc ttgctgctaa agtaggacaa aaaagtgtag
      181 tggagataac tgactattta tttgaatggc aagacaattt agaagttgga gcggagaatt
      241 atcttgtaca atatggttgg gatagaaata ttgctcactg gacaataaag acagttagct
      301 ttattttctt ataagtcatt atgaataaag cttggttatt ttggagtgtc atagtcttat
      361 atttttttat aaagtttttt gataaagttt tagatataaa gctttttggt tctattcaaa
      421 tatggctaga taatctccct attccgatga aaatactgtt aacaatagca ttagttttgt
      481 ttttattcat tgtatttcca tatagaggaa aacggtaaaa acggtaatta gatatataaa
      541 aggagctgaa agctccgtaa aaaacctact cgaagagtag gttttttctt atcttgatac
      601 tagtaggaaa taactctcat gctattttta gggtttcgac agggtctaaa cccttgatac
      661 tactgacttt ttaggtaaaa aaatgccctt gacttttttc aacggatctt ttataattta
      721 gttgttcaga aaaaattata aaaagagaaa aaaggcaaag gtatttttgt atttctttgt
      781 aattacaggt aaattataac atggagaagt gggaaaatca agataaaatt cttttagata
      841 aaaataaaag aggcaaggat agaaactggc gaggacgaaa attattaagt ttgaaattgg
      901 cagatatttt taaagagtta ggttataggg aaaccttgat agaacgcgtt gagacttgtg
      961 gagatactct tcgatttatt cgtcgagaag atgggagttt gcgtttatat caagcctatt
     1021 tttgtaagaa taaattgtgt cctatgtgta attggagacg gtcaatgaaa tattcttatc
     1081 aaacatctca gatagttgat gaagcaatta aagaacaacc aaaagggcgt tttcttttct
     1141 tgactttgac tgtgaaaaat gttccaggta aagaattgaa cgcaacaatt agccagctaa
     1201 ctcagtcctt tgaccgtctt tttagacggg caaaggtaaa gaaaaatcta atcgggtttt
     1261 tacgttcggt tgaggtgact cataatcaag aagaagagac ctatcaccct catatccatg
     1321 ttttgatgat ggttaagtct agctatttta gtggggctgg agataattat gtatctcaag
     1381 aagaatgggg gcggatgtgg gaacagtcgc ttaaggttga ctatgtgcca atggttgata
     1441 ttcggtcagt taaagaaata ggaaaaggtc ttaaaggggc aattcttgaa acggcaaaat
     1501 atccaattaa gccgattaag ttagatgttg aaaacaagca agttgttggt gatttgtata
     1561 atgggttata tcgtaaacgg caattgggtt acggtggatt gtttaaagaa attcggaaga
     1621 gattgcaact gtctaatgtc gaaaatggag atctggttta tacttctgat gacaatgatg
     1681 aaatgtcaaa aggtacaaaa atagtcgcga tttggaatgc gactaaacaa aactattttg
     1741 taaaaaataa gggttggaat taaagtatca actcttttat tataacataa aaaagagtaa
     1801 aatagacttg atttttttga gtttagatgt atattgaagg tgtgaaaatt aaaaagatag
     1861 ctatgttttt tctgggtata cttgttgggg tatttattgt tctatttttt agaaattatt
     1921 ttgttttact tttggaatat atttttggtt aaaaagcacc ctctaaaaag ggtgcttttt
     1981 gtgcggttat tcgcacgaaa gttctctgca agagttcctc ggaagagcgt ttgtattttg
     2041 attgtacgtc aaaactataa aaacatttac tctttgtcaa aacgagtata aagagattat
     2101 ggaaaatgtt aatcaagcaa aagaggaatt aaagagaata gatgaattaa tagccgtcag
     2161 gagctccaga attgattttt tagaggataa aacccttaga attacaggga accaaagatg
     2221 agcttaaaaa cgaaatggag agcctaaaaa gagatttatc tttttttaga aacgaaaata
     2281 ctcgactgaa aaatgtagtt tcagattgta tcaaggtagt atttttgggg tatttttagt
     2341 agaaagtata ttgtaatttc tgagcgattt atgccgtgaa agctacttga ccgtaagcta
     2401 gatcaaagta cgctagtcag ggacgagccg aaaggctgta gcgtttcgga gcggcacgga
     2461 caaagtacgt cgacctaggt tacttgcggt caagtagacc atggaataaa acaagcgggt
     2521 atgatataaa aaagttatcg gcaaaccgaa atatagactt gtttttttgt ttataaaaat
     2581 gtattattat attgagaata agattgttta atttatttag agaggagtgt aagttgatca
     2641 gtaaacgatt ttaattctgc ctttaaataa taaggagttt gttatgaata aaaaattttt
     2701 gaaatgtggt actttatttt tgatttcttg ttctatttta ggaagtacta ttcctgcagt
     2761 tacagtattt tctgatgaag taacaattac ttataattca gagaataatt cagaaaaaaa
     2821 tgaattatat aatcaacttt ctgctg
//
LOCUS       DAVHSL010000102         2763 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000102 DAVHSL010000000
VERSION     DAVHSL010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.104"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(346..642)
                     /locus_tag="VVR39_002156"
     CDS             complement(346..642)
                     /locus_tag="VVR39_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEU6031542.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(1185..2078)
                     /locus_tag="VVR39_002157"
     CDS             complement(1185..2078)
                     /locus_tag="VVR39_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031543.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
BASE COUNT          972 a          514 c          303 g          974 t
ORIGIN      
        1 aataatatct agaaaataca aaataaataa ataaatgaat gattgtaaaa tttggaaaga
       61 ataatatttc ttgacaatgg caagaagata gagaaaaata tagtttttcc ttatatagaa
      121 agtatttatt tttttacttt ggataggcag tttcatatta taacgattca aagtagcgta
      181 atctactacc aaaaaaagta aaaataattt cccttgaaaa ggaagatagc ttttaaaata
      241 gattgacaaa cttatgataa caaaaaacaa aagggttatc ccaataaaat taagataacc
      301 taaaatactt tcacattctt ttttagaaag tattttcatc tagttctacc atagagctgc
      361 tttagcagca cctttctttt tcaatatata aagaactgtt gctgcaatac ccgaaccaat
      421 agaacctact cctgtgattg cacctacaat tgaaattact gctgtaactg tactataagc
      481 actaatcaaa ttgactacag tagcagcagc ttttgtcgaa attcctaatg tcccagccaa
      541 cataggaaaa gaaacaacac ctaagcttaa ccaactaatg actgctaaca ttgctgaaac
      601 aataagaaat ttattatgaa attccattct tttagatttc attttagtgt actccttttg
      661 tatattatgt atgttttatt gagagttaat tcgcacatgt tgtattccta actctcttca
      721 aatgttcgtc tatattttat actactttta ttaacatatc tataataaat aaattactac
      781 tacattttcc tagattatca aattactttt atatcactaa gactcaataa aagataatgt
      841 ctatttaact tttatacgat tactacctcc tttttagttt acacttccta catcataaat
      901 aaacatactc aaccctcaca atctccaaat aactcttcta tatcattgaa aattgagttt
      961 catcctctat actaatgtag gaaacctatt aaaacattcc tttaatccaa tataagaata
     1021 ccttgttcca ttaatctcta cccgatatta tagatagaac caaattccta tacttaaaag
     1081 gacaaataac gttccaccca taataaacct cctttctttt tgaaaacgtt ttctttatag
     1141 gtttagtata gcaaaaacat gaaaaaaaca acatgactta gaagtcaggt tgttgggaaa
     1201 tctatctgtt tttctgctaa aattctctga actaatacct gatcgtctag caattctgct
     1261 agagaaatcg ccttttcata gaaactttct gcctctaaaa tattcttgtc tacaaataaa
     1321 gcatattttg cctttagcaa aaatagatga ggtcggtaaa aaacatgtct tgttttagca
     1381 ataattttct caaatgtttg aatatatatc agactatctt ctgtctgaat ttggataaat
     1441 aggctcagaa gaactttttc catttgaact aggctagcct tatcttcata ttctgaacat
     1501 agcaatactt tttgagctaa ctcctcaaaa tgttctttat cttctaatcc catagcacaa
     1561 caaaagaaat acaattcaat aatcaacaaa tcatttacag aaaaatattt cttttttaat
     1621 aactgctgga aatattcttc cactaaccct aaaccgtagg tcacatctga actaccataa
     1681 atatcaaaac gagcttgtgt cacatccaca attaactgct cttcctcagg caaattctca
     1741 taatagtttt catatatttc ctcaagtata gcttcttttc gttcgattct tcccttatca
     1801 gcgtaggttt gagaatgaat cagctcatct ttgagtttta ggaatccttt tggaatctct
     1861 ataaccttaa catccacaat attctgtaat gatactccaa gtttatccgc aatcaataat
     1921 aatttaggaa gtgttgctaa agcttgccca ttttcaatac gtgctagctg acgaatcgtc
     1981 aactctgatt catcaccaca aatatctatc tgagtttttc cacaagatcg cctaatagtt
     2041 ttgattttat aaccaatttc acgtttcaac tcatccatag taatactcct taagttgatt
     2101 acaaagattt ctttttcttc ctaattcttt tgtcaatcat atataaaacg ataagcgaaa
     2161 acagcggtag aacaatataa ctcttttcac tcattatcag ctgaaatccc agggttgcta
     2221 gtatcttaaa gatgaaaata ttcatcaaaa atagaaaaac aaatactaaa aaatatttta
     2281 aaaccttctt catttctttt cttcaacttt cctaatttct acacctattt tatcgaaaat
     2341 atatataaaa ctccaaataa acacttcgac tgcacttttt ttggcaaaaa atagacagaa
     2401 caaacatcct acctactaaa aatatgatat gaaaggaaat tgatttttta ctgtcaccct
     2461 aggcaagctt gaaacaaata aatcattgat agtaacactt acgacatcct atttattact
     2521 tcaatttcta atgtctctgc tatttctaag ctacctctgg tatgatctat tcctagtcag
     2581 aatagataac accgttctaa attacgattc atagttactc cttttttgac tcgttactat
     2641 aagactcctc tttacatgcg caaaataatt ttgattcaga ttcatcattt atagttttga
     2701 ttatttttta acagattttt ctgttttctt ctccgaagac tttaaaaatt tttttctaat
     2761 taa
//
LOCUS       DAVHSL010000103         2294 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000103 DAVHSL010000000
VERSION     DAVHSL010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.105"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            107..289
                     /locus_tag="VVR39_002158"
     CDS             107..289
                     /locus_tag="VVR39_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6031544.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            299..664
                     /locus_tag="VVR39_002159"
     CDS             299..664
                     /locus_tag="VVR39_002159"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6031545.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            661..1851
                     /locus_tag="VVR39_002160"
     CDS             661..1851
                     /locus_tag="VVR39_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6031546.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
BASE COUNT          933 a          308 c          350 g          703 t
ORIGIN      
        1 tataacaaga ggatagaaat gaccgaatta gaaagaaaaa atcgaaaaat tagctaagaa
       61 atattctaat aacttaaaca tcaaagttca agagagagtt cgtgaaatgg caaatgataa
      121 taagagccat tatttgatat acagagtttt aggtatttca tttgaagaag gagaaaatat
      181 cgatttgtat caaaataaag gtcgtttttt atacaaatat gctggttcat ttttagaaga
      241 agctgcagta ctatccttta acgaaaaatt tggtacagaa aatacttaaa aagttaacat
      301 tcctaattct gaaagtacaa aacctaagac ttttgaaatt gattgtttag tcggagaaaa
      361 acacgcatac gaaataaaat ggtgggatgc aactacagat ggagaccata taactaaaga
      421 acacactaga ataaaagtta ttcataacaa aggatatata ccaattcggt taatgttcta
      481 ctatccaaat agaactcaag ctataaaaat tcagcaaact ttagaaacat tgtataacgg
      541 tattggaggg aaatattatt atggagattc tgcctgggaa catttaagag cagtgaccgg
      601 tattgattta cttagtattc taacagatat tgcaaataaa aaaacagggg taaaatcaaa
      661 atgacagtat taaaaggaga taacttagaa atattaaaaa ctattgaatc ctcaagtatt
      721 gatttaatct atatggaccc tcctttcttt acacagaaaa cccaaaaatt atctaataac
      781 aaaaatatta tgtattcatt cgaagatacg tggacttcga ttgaggatta caaagaattt
      841 ttgtctgtaa gattagaaga atgcaaaaga gtgctaaaaa atagtggcag tattttcgtt
      901 cattgtgata aaattgcaaa tcatcatatt agattaattt tagataatat ctttggagca
      961 gatatgtttc aaagcgaaat tatatggaac tataaacggt ggtctaattc aaaaaaggga
     1021 ttattgaaca atcatcaaaa catttacttt tattcaaagt caaaagattt taaatttaat
     1081 acaattttta cagagtattc ttctactaca aatatcgacc aaatactagt ggaacgaaaa
     1141 cgagatggaa actctaaaac tatatataaa gttgataata atggtaacta tattctagca
     1201 aaagagaaaa atggagttcc cctttcagat gtttggaata taccatttct taatccaaaa
     1261 gctaaagaaa gagtaggtta tcctacacaa aaacctattc tgttattaga acaaattata
     1321 aagattgcta ctgataaaaa tgatatagtt ttagacccgt tctgtggaag tggaactact
     1381 ttagtagcct ccaagatttt gaatagaaat tatatgggga ttgatttatc tgaggaagct
     1441 atcaatataa ctcagcaacg tctggaaaat gttataaaaa caagttcaaa tttattgaat
     1501 aaaggaatcg aagcatatag aaccaaaact gaggaagagg aaaacattct taaattatta
     1561 caggcaaaaa ttgttcaaag aaataaagga attgatggtt ttttacctaa acattttcaa
     1621 aaaaaaccga tacctataaa aattcaaaaa aataatgaat gtctgaatga gagtatctct
     1681 ttattacaga atgctataaa ctccaaaaaa cttgattttg gagtagttat aaaaactcat
     1741 tcagataatt tattatttga ttttgatacg attcctgaaa atataatagt agttgaccat
     1801 tttgaactta caatcgaaaa atggttaagt aaaagtcaac agttactata gtttgcaaat
     1861 tatttacaga aagaacaaaa aatgctctga aacactgatt tcaaagcatt ttttgttagt
     1921 ttaaaattac tcccattctt cttttccaaa cgtacaatat atccaaaacc attcaaaata
     1981 ctagattcta ttttttataa tattactaaa tccacctaat tataggacgt tttcagattt
     2041 ttagtcccgt cccagtccca gtaccggaga aatattgttt taatataata tctctttttg
     2101 tcttctaagc tcttaaaagc aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc
     2161 atattagggc aaataaaaag ctttaagaca gatgacaaat ttaagtcaaa taagaaagac
     2221 catagcaaag gtgcagagag ataaatattg gcggtcttcg gactgccttt atttttttat
     2281 ccatttttca aatc
//
LOCUS       DAVHSL010000104         2278 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000104 DAVHSL010000000
VERSION     DAVHSL010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.106"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            116..931
                     /locus_tag="VVR39_002161"
     CDS             116..931
                     /locus_tag="VVR39_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FRG domain-containing protein"
                     /protein_id="HEU6031547.1"
                     /translation="MIPGIWREAYSVSDSRGERIPIHRTNFYNPKGEVVVMPSQNVLL
                     EKFMSKAMTEDILGPKNEVQWLELAQHYGLPTNLLDWSTDPLVALFFAASTVDCKNDN
                     ETYLTEDQVIVREDDEDEDEIIHAHASVWVINPLEINQILLNEPGIEGVFQSFNPNDI
                     EKINKEISLNCGTFCFEGSKINPRITRQSGNFTHSGTKLTHPLDFLAAVQSKIIKINI
                     PYSCISKIITDLNKLDITNESIYFGRTERDLTAERIKGEVYSEFKEYLNSIIE"
     gene            992..1705
                     /locus_tag="VVR39_002162"
     CDS             992..1705
                     /locus_tag="VVR39_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU6031548.1"
                     /translation="MSYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTERLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            1739..>2278
                     /locus_tag="VVR39_002163"
     CDS             1739..>2278
                     /locus_tag="VVR39_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031549.1"
                     /translation="MTIEEYNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISE"
BASE COUNT          779 a          383 c          400 g          716 t
ORIGIN      
        1 aaaaaaatat tttgtaaatt caattgaatc gtacattcaa actattagag aaattaattc
       61 agcgaatcca tctcatagac tatggtatag agggcaaaag agttccgaat atggcttgat
      121 tcctggaatt tggcgtgagg cttattctgt ttccgattct aggggagaga gaatcccaat
      181 tcatcgaaca aacttttaca accctaaagg agaagtagtt gttatgccat ctcaaaatgt
      241 tctccttgaa aaatttatga gtaaggcaat gactgaagat atcttagggc cgaaaaacga
      301 agtacaatgg ttagaattag cacaacatta tggcttacca acaaatttat tagattggtc
      361 tacagaccca ttggttgcat tattttttgc tgcctctaca gttgattgta aaaatgataa
      421 tgaaacttac ctaactgaag atcaagttat tgttcgagaa gatgatgaag atgaggatga
      481 gataattcat gctcatgctt ctgtatgggt aattaatccg ttagaaataa accaaatctt
      541 actaaacgaa cctggtatag aaggagtttt tcagagtttc aatcctaatg atatcgagaa
      601 aattaacaaa gaaatttctt tgaattgcgg cacattttgt tttgaggggt ctaaaattaa
      661 tcctcgtatc accagacaat caggtaactt cacgcactca ggaacaaaac ttacgcatcc
      721 tctagatttt ttagcagctg ttcaatcaaa aattataaaa ataaatatac cttatagttg
      781 tatttccaaa attataactg acttaaataa attagatatt acaaatgaat ctatatattt
      841 tggacgtact gaaagagatt tgactgcaga aagaattaaa ggcgaagttt attcggaatt
      901 taaggaatat cttaattcga ttattgagta atcattattt gtacaccccc atttgaacca
      961 ttgcaccccc tctagaaagg aaaacctcaa attgtcctac aaatttctac tcttcgacct
     1021 cgaccacact cttcttgatt ttgatgctgc tgaggatgtg gctttgaccc aacttctaaa
     1081 agaagaagga gttgcggata ttcaggctta taaagattat tacgttccta tgaacaaggc
     1141 tctctggaaa gacttggagc taaagaaaat cagtaaacaa gaactggtta acacgcgctt
     1201 ttctcgttta tttgctcatt ttggacagga aaaagacggt agttttcttg cccagcgtta
     1261 ccaattttac ctcgcccagc agggacaaac actatcgggc gctcatgatc tcttggacag
     1321 cctcattgag cgtgattatg acttgtatgc tgcgacaaat ggcattactg ccattcagac
     1381 agaacgtttg gctcaatctg gtctagcacc ttatttcaat caagtcttta tctcagaaca
     1441 gttgcaaact caaaagccgg atgctctctt ttatgaaaag attggccagc aaattgctgg
     1501 atttagtaaa gaaaagacgc tgatgattgg agattctcta accgccgaca ttcaaggtgg
     1561 caataatgcg gggattgaca ctatctggta taatcctcat cacctcgaaa atcacacaca
     1621 agcccagccg acttacgaag tctattctta ccaagacttg ctggattgtt tagataaaaa
     1681 tattcttgaa aagatcacat tttaaaggag acgagctaat gactacaaaa aagctaatat
     1741 tactattgaa gagtacaatg aagctgttaa ttatgaattt acatctgaca cttgtcaatt
     1801 agcaaatagt atttatcaat ctctttttaa gttttttgat aagaaaaatt tctctggcga
     1861 tttaattttt acttggaaat ctccatcatt agtcaaagaa ggggattata ttgggagaag
     1921 ggattcacaa gtagataatc ttagagtaat aggaaatata tttccgaatt atcttactaa
     1981 tcgaaaatat agcctcaata tgaatcgtaa tggctgtatg ggagattttc ctcatgactt
     2041 ttttgatata tacctagatc atgtagcaaa atatgcctac gaacaaaaag ttaataatat
     2101 taaagagtat tatcctttaa aaagagcgat tttacaccaa gagaatgcat tgtattttcg
     2161 attgttttct aattttgacg actttttaga aaaaaattat ttaaagacta tatggcaagt
     2221 ttctaaagaa actccttttt ctgaaatgga ttttaatatg tttaaaaata tttcagaa
//
LOCUS       DAVHSL010000105         2266 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.107, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000105 DAVHSL010000000
VERSION     DAVHSL010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.107"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..215
                     /locus_tag="VVR39_002164"
                     /pseudo
     CDS             1..215
                     /locus_tag="VVR39_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(384..936)
                     /locus_tag="VVR39_002165"
                     /pseudo
     CDS             complement(384..936)
                     /locus_tag="VVR39_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1012..1452)
                     /locus_tag="VVR39_002166"
                     /pseudo
     CDS             complement(1012..1452)
                     /locus_tag="VVR39_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1443..1751
                     /locus_tag="VVR39_002167"
                     /pseudo
     CDS             1443..1751
                     /locus_tag="VVR39_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1906..2229)
                     /gene="tnpB"
                     /locus_tag="VVR39_002168"
     CDS             complement(1906..2229)
                     /gene="tnpB"
                     /locus_tag="VVR39_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6031550.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
BASE COUNT          708 a          470 c          420 g          668 t
ORIGIN      
        1 ctagaattct ccttagaaag cgtcgattca agtgttatca ctgttcaaaa atgatggtcg
       61 ctgaaacttc tatcgtcaag aagaatcacc aaatccctcg tatcatcaac caaaaaattg
      121 cgcaaaagtt aattgaaaag aattctatga ccgatattgc ccatcagctg gccatttcaa
      181 cttcaactgt cattcgaaag ctcaatgact tccacgttta cgagagtttc ctcgtttgga
      241 agacattcta gaagatagga tagatatttc tcgctattta taatggattg aaataagata
      301 tgaacaaatc gattaggaaa ggaaaattga tttatagaaa tgttttagca gtcgatgcgt
      361 actgttatag attcaacgca ctataattga tgacgtttag ctgtttccaa caagctcata
      421 ataatagctc ttgctttagc tccttcaaaa ctttgagaaa ataaccaccc tcgctttttt
      481 aaactgagct caggctaaaa gagtccactg gactctttta ctccgtccca taaccaatga
      541 tttaatggcg cgttcagcta gattattgga aaggaccaga tgtccgtctt tcaaaatagt
      601 cttaaaggtt tcttcatact tgaggctgta ttcaattgcc cttcctagtt ttgaacctgc
      661 taaaactgac tgacggccgg caccaagcaa agaaatcttc cattaggttg gagctcttct
      721 tgacgtttct gtagtcgttc atcagctggc aatgtcctcc cagtctcttt ccaaggaaaa
      781 taactgatca caataggcta atcctttagc tcctaaggat gatttatctg cttgcttggg
      841 ggtcgcttca aaaaacttcc ttctcacatg tgcccaacat ccaacaagtt cagcttcttc
      901 cagttgacga taagcttcta gcggttcgca gtttaccaag cttagcgtcg ccttgctcct
      961 aaaccttgga ctgctatcgc ataggcagaa ctagaggact aaagtcctaa gttactgccg
     1021 caacatatca caatgaacat agccagaata atctcctagg aattcttgta ctaccgaacc
     1081 actccgactc tgatcatgat ggtacagcgt gattgcttga ttctcaactt tcccagacaa
     1141 aaaggttcaa tagtaggtca gatggctatg actctctaga acccgataag aggtttcatc
     1201 tgcatgaaga agagcttgtt ctaacaactt ttctcgtaaa agattataaa ggggctccaa
     1261 ataatagtga ctcgtcttga tatgccaatt agaaatttcc ttacgtgtga ttggtaaacc
     1321 catcttagcc caatcttctt cttagcgata attgggtacc ttcagaataa acttctgatg
     1381 gatggtgtga gcgataatag aagctgagcc aaggctatgc gccaaagggg ctttaggaat
     1441 aggagctttc acaagcttat ccagatgatt atcttttact cgttatggac aatgctatat
     1501 ggcataaatc aagtacctta aagattccga ctaatattgg ctttgcattt attcctccat
     1561 acacaccaga gatgaacccc attgaacaag tgtggaaaga gattcgtaaa cgtggattta
     1621 agaataaagc ctttcaaact ttggaagatg tcatgaatca acttcaagat gttatacaag
     1681 gactggagaa ggaggtgata aagtccatcg ttaatcggag atggactaga atgcttttta
     1741 aaatcagatg agtataaaaa gaaagtcctc atttcaatag aaatcacgac tttctgatgg
     1801 atttatagta aaatgaaata agaacaggac aaatcgatca ggacaatcaa atcgatttct
     1861 aacaatgttt tagaagcaga ggtgtactat tctagtttca atctactata tttttggagt
     1921 gatagaaaag cctttcatca gccaatctac ttgttcaggt gcgagagctt tgacatcctt
     1981 ttctgtactt agccaagtca gttttccgtt ctcaaagcgt ttatatagta gccaaaatcc
     2041 ttgaccatcc cagtaaagga ctttaaagcg gtctttacgt ccaccacaaa agagaaaaac
     2101 ttgacctgag aaagaatcca attcaaagtg ggttttaacc agataagcca gtgaatcgat
     2161 tccttgtctc atatccgttt tcccacatac gagatagacc tgccctaggc tagatagatg
     2221 aattgtcata gagcaacacc ttatccaaaa gctgttctac catttc
//
LOCUS       DAVHSL010000106         2190 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000106 DAVHSL010000000
VERSION     DAVHSL010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.108"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            138..944
                     /locus_tag="VVR39_002169"
                     /pseudo
     CDS             138..944
                     /locus_tag="VVR39_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1094..1348
                     /gene="blpM"
                     /locus_tag="VVR39_002170"
     CDS             1094..1348
                     /gene="blpM"
                     /locus_tag="VVR39_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU6031551.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            1364..1567
                     /gene="blpN"
                     /locus_tag="VVR39_002171"
     CDS             1364..1567
                     /gene="blpN"
                     /locus_tag="VVR39_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU6031552.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGL
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1811..1960
                     /gene="blpO"
                     /locus_tag="VVR39_002172"
     CDS             1811..1960
                     /gene="blpO"
                     /locus_tag="VVR39_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU6031553.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            2064..2183
                     /locus_tag="VVR39_002173"
     CDS             2064..2183
                     /locus_tag="VVR39_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU6031554.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
BASE COUNT          722 a          318 c          471 g          679 t
ORIGIN      
        1 ccctgcgaaa caaaatatgg tatagtatag tatattgaaa ctagaatagt acgcctctac
       61 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttatcct gttcttattt
      121 cattttacta tagttctatg aatgatgaag caagtaaaca actaactgat acacgattta
      181 aatgtcttgt tggtgttcag cacacgactt ttgaagagat gttagctgtg ttaaaaacag
      241 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
      301 ttatggccac tcttcactat gtacgagaat accgcactta tgaagaaatt gcggctgatt
      361 ttggtatcca cgaaagcaac ttactccgtc ggagccaatg ggttgaagta actcttgttc
      421 aaaggtggtg ttacgatttc aagaactcct ctcagttctg aagacacggt aatgattgat
      481 gcgacggaag taaaaatcaa tcgccctaaa aaaaacaatt agcgaatgat tctggtaaaa
      541 agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt
      601 tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata
      661 tcggacaaac tggtaaaatc ttggctgaca gtggttatca aggacccatg aagatatatc
      721 ctcaagcaca aactccacgt aaatccagca aactcaagcc gctaacagtt gaagataaag
      781 cctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
      841 aaacgtttaa aatgatttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
      901 tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
      961 atgtaatttt tgcaattcaa gacgtttcga tgactattca agatctggat gaaaaatttt
     1021 aaaaaacgat gatatactaa acttgtcaaa gttacaacaa gacaaaaatt aaaaataaaa
     1081 aagagtattt gtcatggata caaaaattat ggaacaattt catgaaatgg atataactat
     1141 gttatctagt attgaaggag gcaagaataa ttggcaaact aatgtcttag aaggtggtgg
     1201 tgctgctttt ggtggctggg ggctagggac agctatttgt gctgcgagtg gtgttggagc
     1261 accatttatg ggagcatgtg gatacatagg agctaaattt ggtgtggatc tttgggcagg
     1321 agtaacaggg gcaacgggtg gattttaata aaaggagact tgtatgaata cttattgtaa
     1381 tataaatgaa acaatgctga gtgaggttta tggaggtaat tccggaggag cagctgtagt
     1441 tgctgcttta ggttgtgcag cgggtggagt gaaatatggg agacttctag gactatgggg
     1501 cgctgcaata ggaggaattg gaggagcagt ggtttgtgga tatttagcct ataccgctac
     1561 atcataaaaa tgaaagctaa attttatgaa ggctatattc tttattattc tcttcgcttt
     1621 tcaaacctat cttatttatc tatccataag tatctccgat aaaaaacaaa agactattga
     1681 attaacatca ttgaattgtt ttgtcatatt atttctaatc tatgataaat taatttttct
     1741 ctttattgcc tatgtttttt tgataatttt tatattaaac ttgttccgta actgaaaagt
     1801 gatatactat atggatacaa aaatgatgtc acaatttgca gttatggata atgaaatgct
     1861 tgcttgcgtt gaaggtggag atattgattg gggaagaaaa attagttgtg cagcaggggt
     1921 tgcatatggc gcaattgatg ggtgtgcaac aacggtttga catttctatt gggaccattt
     1981 gctataggaa taggtgtaac tggtgctgca ggtggagcta tacttggagg tgtagcctat
     2041 gcagcaatat gttggtggta attatggatt ttaaaagttt tattattggt ttagtagttg
     2101 gtatatttgg tccttatatg gatgacttaa ttagaaaaat attttcaaaa tcttccaaaa
     2161 aggatacgga tagtactctc taaaaaataa
//
LOCUS       DAVHSL010000107         2101 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000107 DAVHSL010000000
VERSION     DAVHSL010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.109"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(140..298)
                     /locus_tag="VVR39_002174"
     CDS             complement(140..298)
                     /locus_tag="VVR39_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU6031555.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(370..819)
                     /locus_tag="VVR39_002175"
     CDS             complement(370..819)
                     /locus_tag="VVR39_002175"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031556.1"
                     /translation="MVNCEQLEAYRQLEEAALVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLLEDFFAWCRRQSVLSGSKLGRAI
                     EYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQWTLLA"
     gene            complement(892..1482)
                     /locus_tag="VVR39_002176"
                     /pseudo
     CDS             complement(892..1482)
                     /locus_tag="VVR39_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1406..1600)
                     /locus_tag="VVR39_002177"
     CDS             complement(1406..1600)
                     /locus_tag="VVR39_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031557.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1665..2015)
                     /gene="tnpB"
                     /locus_tag="VVR39_002178"
     CDS             complement(1665..2015)
                     /gene="tnpB"
                     /locus_tag="VVR39_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6031558.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKSFS
                     ITPKINSSESRDFY"
BASE COUNT          594 a          452 c          404 g          651 t
ORIGIN      
        1 gtcaggggtt ttgtaagtta catctagttg agaggggtat gaatgatttg ggttgaatat
       61 cgtaaccgcc caataacgaa gtatattgaa aaatctccag actagagaac tcacggatag
      121 ttcctaatct ggagatttct tatttgcact tttcttgtac aactttagtc cacggtaaat
      181 aggcctctaa aacctctttg tttacgagag tttcctcgtt tggaagacat tctagaagat
      241 aggatagata tttctcacta tttaattgat gacgtttagc tgtttccaat aagctcataa
      301 taatagctct tgctttagct ccttcaaaaa ctttgagaaa acaaccaccc tcgctttttt
      361 aaactgagct taggctaaaa gagtccactg gactctttta ctccgtccca taaccaatga
      421 tttaatggcg cgttcagcta gattattgga aaggaccaga tgtccgtctt ttaaaatggt
      481 cttaaaggtt tcttcatact tgaggctgta ttcaattgcc cttcctagtt ttgaacccga
      541 taaaactgac tgacgacggc accaagcaaa gaagtcttcc agtaggggtt ggagatgttc
      601 ttgacgtttc tgtagtcgtt catcagctgg caaagcctcc cagtctcttt ccaaggaaaa
      661 taactgatca caataagcta aacctttagc tcctaaggat gatttatctg cttgcttggg
      721 gggcacttca aaaaacttcc ttctcacatg cgcccaacat ccaacaagtg cagcttcttc
      781 cagttgacga taagcttcta gctgttcgca gtttaccaag cttagcgtcg ccttactcct
      841 aaactttgga ctgctatcgc ataggcagaa ctagaggact aaagtcctaa gttactgccg
      901 caacatgtca caatgaacat agccagaata atctcctagg aattcttgta ctactaaacc
      961 actccgacgc tgatcatggt ggtacagcgt gattgcttga ttctcagctt tcccagacaa
     1021 aaaagtccaa tagtaagtca actgactatc actctctaga acccgataag aggtttcatc
     1081 cgcatgaagt aagggcttga gtcaatagtc tcgttataaa ggggctttag gaataggagc
     1141 tttcacgatt ttatcactcg gatttttatc actgcatgct tggcatttgt aagcgtgttg
     1201 gatatgatct atgcgtttta attgcgcagg aataaagacc aattcttgtc cttgaagact
     1261 ccctccaatc tcttttagat ctccctgaca atcagggcaa atcctctctt ctacttgatg
     1321 atgaacttct tctgaatcaa attgggcaag aagagcttgg cgtttccctt tagatttctt
     1381 acgtttgtag gtaatttcct ctgtttcaac tgggaacatc tccatcttcc tcagatggag
     1441 actcttcctc aaaaaggttg agttgtccag aggggcaaac acttttctca gaggattttc
     1501 catagagctt ttgagtcaga taagccactt gttcacgaag aagggcaagt tcattggtga
     1561 gactatcaat tgtagcactc tgttgttgaa tgattttcaa tcttcttcca tgagcttccc
     1621 tctctgtttt ctaactttat tatactaaaa agaaagtcct catttcaata gaaatcacga
     1681 ctttctgatg agtttatttt gggagtgata gaaaagctct tcataagcca gtctacttgt
     1741 tcaggtgtga gagctttgac atccttttct gtactgggcc aagtcagtct gccgttctca
     1801 aagcgtttat atagtagcca aaatccttga ccatcccagt aaagggcttt aaagcggtct
     1861 ttacgtccac cacaaaagag aaaaacttga cctgagaaag gatctaattc aaagtgggtt
     1921 ttaaccagat aagccagtga atcaatgcct tgcctcatat ccgttttccc acatacgaga
     1981 tagacctgcc ctaggctaga tagatgaatt gtcatagagc aacaccttat ccaaaagctg
     2041 ttctatcatt tcgagattga gagattgaaa aaaacttact tcaagcttgc caatacgaat
     2101 t
//
LOCUS       DAVHSL010000108         1652 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.110, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000108 DAVHSL010000000
VERSION     DAVHSL010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.110"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(147..347)
                     /locus_tag="VVR39_002179"
                     /pseudo
     CDS             complement(147..347)
                     /locus_tag="VVR39_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(435..809)
                     /locus_tag="VVR39_002180"
     CDS             complement(435..809)
                     /locus_tag="VVR39_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031559.1"
                     /translation="MTTSYLKSKSDNGGGTYCLDNIELLANIDFIKIFEEISTSSKID
                     IVTYSFYDDEFLKALLYDKINVRVLLSKISNQSQHYTDLIREIVPNSEVIQVEETHAK
                     IVLAEPNFVYLGSQNIDQSDWF"
     gene            complement(952..>1652)
                     /gene="phtB"
                     /locus_tag="VVR39_002181"
     CDS             complement(952..>1652)
                     /gene="phtB"
                     /locus_tag="VVR39_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU6031560.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESP
                     EESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIM
                     AEAEKLLALLKESK"
BASE COUNT          448 a          303 c          261 g          640 t
ORIGIN      
        1 acacttaaaa aagtaaaaaa gctaaaaata ctccaataat tattttaaaa ttcttcttcc
       61 tttcttttta agggttttca tttttctatg ttttaaataa ataggatatt aaaaatcgaa
      121 ctcatattat tatacttcct gcgaaactaa aatcctagtt cacggttgat aattccagca
      181 atcaaattca ttcgtaatcc aaagcgttta cgtcgatttc gataggttgt tgaaaacatt
      241 ttaaacgttt ttactttggc aaaaatattc tcaaccttga ttctctcttt agatagcaca
      301 tggttatagg atttatcttc aagagttagt ggcttaagtt tacttgattc ataattcata
      361 gttttattgt attatatttt tgtttcgcag gaagtctatt tataaatttc ttggtctcta
      421 ataactacgc ttgtctagaa ccagtctgat tgatcaatat tttgggaccc tagatataca
      481 aaattaggtt cagccagaac gattttagcg tgagtttctt cgacttgtat cacctctgaa
      541 ttaggtacaa tctctcgaat taaatctgtg taatgttgac tttgattaga gattttactt
      601 aataggactc tgacattgat tttatcatag agtagagctt ttaaaaattc atcatcataa
      661 aaactataag taacgatatc gattttagaa gaagtagaaa tttcttcaaa tattttgata
      721 aaatcaatat ttgctaacaa ttctatattg tctaaacagt aagtgccccc accattatca
      781 gatttagatt ttaaataaga tgttgtcata acttttacac cgtttccctt tcaattttat
      841 aaatctatca ttttcatgaa aaaaatgaga actagaactc acattctgct ctcatttttc
      901 gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc tttacttact
      961 ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt tgtcctgggt
     1021 gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg acttgataat
     1081 tggatcctgg atttttccaa gtaaatcttc agcctctctc agtttttctt caaccttttc
     1141 agtctcgacc tgaggttctt ctgattcctc tggtgattct tcttctggtt cctctgttgg
     1201 ttttggagac tctggtttct cgctttgcgg tttctcttct cgaggggttt cttcctcagg
     1261 tttttctgtc tgaggtttct cctcgcttgg tttttccgtt tgattggtat cagcttgacc
     1321 atttttgttt ctttgaacat ggtcgctagc gttaccaaaa ccattatctg aatgcggacg
     1381 ttcgtttgga tgttcgacat agtacttgac agtcgccaaa agatcctcaa gactataccc
     1441 cttaggtgcc tcataaaggc cttcgtcaaa ccactcaaat ttgatgttat ggtaatggtc
     1501 ataatgaggt atgattaaac taccgttttt gacttctaca gtatattgaa gattgtaagg
     1561 catacgatca agtggcacct tcttagctgc tttcacgcgg ttgtagatag cttctgctcc
     1621 ttttgcctca gtatttcctg aatcctgatg tt
//
LOCUS       DAVHSL010000109         1597 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.111, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000109 DAVHSL010000000
VERSION     DAVHSL010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.111"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(1..581)
                     /locus_tag="VVR39_002182"
                     /pseudo
     CDS             complement(1..581)
                     /locus_tag="VVR39_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(657..1433)
                     /locus_tag="VVR39_002183"
     CDS             complement(657..1433)
                     /locus_tag="VVR39_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031561.1"
                     /translation="MFAHLDNSVFLKRNKIWKKTLTYPVEREEITYKRKKSKGKRQAL
                     LAQFDSEEVYHQVEESIYPDCQGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQA
                     CSDKNPSDKIVKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKMGLPI
                     TRKEIANWHIKASQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLTYYWIFLS
                     GKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(1357..1551)
                     /locus_tag="VVR39_002184"
     CDS             complement(1357..1551)
                     /locus_tag="VVR39_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031562.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
BASE COUNT          433 a          344 c          304 g          516 t
ORIGIN      
        1 aagataggat agatatttct tactatttag ttgatgacgt ttagctgttt ccaacaagct
       61 cataataata gctcttgctt tagctccttc aaaactttga gaaaataacc accctcgctt
      121 ttttaaactg agctcaggct aaaagagtcc actggactct tttactccgt cccataacca
      181 atgatttaat ggcgcgttca gctagattat tggaaaggac cagatggtcc gtctttcaaa
      241 atagtcttaa aggtttcttc atacttgagg ctgtattcaa ttgcccttcc tagttttgaa
      301 cctgctaaaa ctgactgacg gcggcaccaa gcaaagaagt cttccattag gggctggaga
      361 tgttcttgac gtttctgtag tcgttcatca gctggcaaag cctcccagtc tctttccaag
      421 gaaaataact gatcacaata agctaaacct ttagatccta aggatgattt atctgcttgc
      481 ttgggggtcg cttcaaaaaa tttccttctc acatgcgccc aacatccaac aagttcagct
      541 tcttccagtt gacgataagc ttctagcggt tcgcagttta ccaagcttag cgtcgcctta
      601 ctcctaaact ttggactgct atcgcatagg cagaactaga ggactaaagt cctaagttac
      661 tgccgcaaca tgtcacaatg aacatagcca gaataatctc ctaggaattc ttgtactact
      721 gaaccacttc gacactgatc atggtggtaa agcgtaatcc cttgtttctc tgctttacct
      781 gacaaaaaaa tccaatagta agtcagctga ctatcacttt ctagaacccg ataagaggtt
      841 tcatccgcat gaagaagagc ttgttctaac aacttttctc gtaaaagatt ataaaggggc
      901 tccaaatagt attgactcgc cttgatatgc caattagcaa tttccttacg tgtgattggt
      961 aaacccatct tagcccaatc ttcttcttgg cgataattgg gtaccttcag attaaacttc
     1021 tgatggatgg tgtgagcgat aatagaagct gagccaaggc tatgcgccaa aggggcttta
     1081 ggaataggag ctttcacgat tttatcactc ggatttttat cactgcatgc ttggcactta
     1141 taagcgtgtt ggatatgatc tattcgtttt aattgcgcag gaataaagac taattcttgt
     1201 cgttgaaggg ttgctccaat ctcttttaga tctccctgac aatcagggta aatgctctct
     1261 tctacttgat gataaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
     1321 ttagatttct tacgtttata ggtgatttct tctctttcaa ctgggtaagt cagagtcttc
     1381 ttccatattt tgttcctctt caaaaagact gagttgtcca gatgggcaaa cacttttctc
     1441 agaggatttt ccatagagct tttgcgttag ataagccact tgttcacgaa gaagggcaag
     1501 ttcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
     1561 atgggcttcc tctccttatt tcctaacttt attataa
//
LOCUS       DAVHSL010000110         1518 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000110 DAVHSL010000000
VERSION     DAVHSL010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.112"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(96..1385)
                     /locus_tag="VVR39_002185"
     CDS             complement(96..1385)
                     /locus_tag="VVR39_002185"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU6031563.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
BASE COUNT          398 a          355 c          327 g          438 t
ORIGIN      
        1 accatgtttt gagctgactt cgtcagttct atccacaacc tcaaaacagt gttttgagca
       61 acctgcggct agcttcctag tttgctcttt gatttttatt gagtataaaa tcctagtttt
      121 tcaaagattt ctgagaagtt ttggctgatt gtctcaagtg acacttgcac ttcttctcgg
      181 gtttggttgt tcttgactgt cacttgtctg ctttcgactt cgctctctcc tagggtgatg
      241 agggtcttag ccgcaaagac atcggctgac ttgaactgag ctttgagctt acggttgagg
      301 taatcacgct ctgctttgaa accttgttgg cgaagagctt ggactagttc tagggctttg
      361 acatttgctc catcacccaa gactgcgata tagacatcta gggcattttc gatagggagg
      421 gccacgcctt gtttttcaag gatgagaagc aggcgctcta caccaagccc aaaaccaaat
      481 ccagcagttt cagggcctcc aaagtaagca accaaaccat cgtagcgacc acccgcacag
      541 actgtcaagt cattgccctc aatctctgtg ataaactcga aaatggtgtg gttgtagtag
      601 tccagaccac gcaccatatt ggtatcgatg atgtaatcta ctccaagatt ttccaacatc
      661 tgacgcacag catcaaaatg agtttggctt tcttcatcaa gaaagtccaa gatagacggc
      721 gcattctcta ctgccacctt gtcttctttt tccttagagt ccaagacacg aagaggattt
      781 tcctccaagc gacgttggct atccttagac aaggtctcct tgagcggtgt caaatagtca
      841 atcaaggctt ggcggtaggc tgcacggctc tcaggatttc caagagtgtt gaggtgcaat
      901 ttgacacctt gaataccgat ttccttcaaa aaatgggctg ccataacgat tgtttccaca
      961 tcggtagctg gattgctaga gccaaaacac tcaacaccaa tctggtggaa ttggcgcaag
     1021 cgccctgcct gtggacgctc ataacggaac ataggtccca tgtagtagaa cttgcttggc
     1081 ttttgcactt ctggggcgaa gagtttattt tccacatagg aacggacaac gggcgcagtt
     1141 ccttctggac ggagggtaat atgacggtca cccttgtcat aaaaatcgta catttccttg
     1201 gttacgatat ctgttgtatc tccgacagag cggctgataa cctcgtaatg ctcgaaaata
     1261 ggcgtacgca cttctgcgta gttgtagcgc ttgaaaattt cacgggcaaa gccctcaacg
     1321 tactgccatt tggcagattc agcaggtaaa atatcctgcg ttccttttgg tttttgtaat
     1381 ttcataggga atcctcttta aacttaatag tcttatttta ccacaaataa agggattaaa
     1441 acagtgagaa aaaaattagg atttaaccca aatcattcat acctctctca actagatgta
     1501 acttacaaaa cccctgac
//
LOCUS       DAVHSL010000111         1371 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.113, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000111 DAVHSL010000000
VERSION     DAVHSL010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.113"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            129..584
                     /locus_tag="VVR39_002186"
     CDS             129..584
                     /locus_tag="VVR39_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6031564.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVHAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYSNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWQKQHKIG"
     gene            749..1048
                     /locus_tag="VVR39_002187"
     CDS             749..1048
                     /locus_tag="VVR39_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU6031565.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          482 a          268 c          234 g          387 t
ORIGIN      
        1 ttcgctcaca ataagagaga acttttttac gaaaatctat tgaatatgcc ataagaagat
       61 tataccacat tgtgtactat ttttggttca tttcactata ataataacga tactagataa
      121 tgaggaaaat gcaatggcaa acccaacttt cggagaaaaa agcgaataca gactatattg
      181 ctcgctatgg cgtacatgca gttatcccta atcctgaaca aaaacaaatt gttcttgttc
      241 aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat tgaagcaggt gaaaatcatc
      301 aggaagccct aaagcgtgag ttgattgaag agcttggttt cacagcagaa attggtacct
      361 attacggaca agctgacgaa tatttctatt ctcgtcatcg tgatacctac tactccaatc
      421 ctgcctacct ctatgaagca actcctttca aagaagtaca aaagccacta gaaaacttta
      481 atcatattgc ctggttccct attgacgagg ctatcaaaaa ccttaaacgt ggtagccata
      541 aatgggccat tgaatcttgg caaaaacagc ataagattgg ctaatactct tcgaaaataa
      601 aattcaaacc acgtcagcgt cgccttaccg tactcaagta tagcctgcgg ctagcttcct
      661 agtttgctct ttgattttca ttgagtataa atcaagcgac tttattcaaa aagtgctata
      721 atagaattag aaaatcggag gaaatattat gaagcttatc aatacgacaa actcacactc
      781 gcaacttgta aaaagtcagc tagaaagtac cgatgcaacc cttgttgagg tttattctgc
      841 agggaataca gatgttattt ttacccaagc tccgcttcac tatgaaatcc tcatctcaaa
      901 caaacaccgt gctattcgtg agcctgaaat cgaaaccatt caagaatttt tcttgaaacg
      961 taaaattgat aagacctctg ttgatgaagc caatatcaag acactctact cagagaaatt
     1021 aattggaatt tcaatcccaa tcaagtaaga aaattgagta aaaactcgat ttgagagaaa
     1081 gtccaataag tctttccata acaaaacgca tagtaacaag agtttctaca cccactatta
     1141 tgcgttttta tcattttgaa atctactgct aatcaatgaa gaagcaaaga tcaaactagg
     1201 cagctagtta caagttacgt aagcgcgtca taacaaggta tctatcctaa ttccccaact
     1261 tccagtatac tagataaaaa ataattatcg gaggaaaggt attgtactat gataattcaa
     1321 ctaagtgatt taggtcaagt tcaccttgtt tgtggtaaga cagatatgag g
//
LOCUS       DAVHSL010000112         1177 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000112 DAVHSL010000000
VERSION     DAVHSL010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.114"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..1084
                     /locus_tag="VVR39_002188"
                     /pseudo
     CDS             1..1084
                     /locus_tag="VVR39_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          380 a          242 c          203 g          352 t
ORIGIN      
        1 tgttctaaaa tgatggttgc tgaaacttct atcgtcaaga agaatcatca aatccctcgt
       61 atcatcaacc aaaagattgc tcaaaagtta attgaaaaga tttctatgac cgatattgcc
      121 catcagcttt ccatctcaac ttcaactgtc attcgaaagc tcaatgactt ccactttgag
      181 tgtaatttta gaaatctgcc taagattatg tcttgggacg ttgaaacagt ccggggagtg
      241 actgtttcaa tcgggagatg gagatgagct ttattgcgca agattttgaa aagctcgata
      301 tcatcactgt tcttgaaggt agaacacaag ctgtcatccg agatcacttt cttaaatatg
      361 atagagccgt ccgatgtcgc gtcaaaatca ttactatgga tatgtttagc ccttactatg
      421 acttggctaa acagcttcgc tttcaaattt ctaggctcag gctgaaacag tctcctagac
      481 tgtttcactc ccgaatgcta aaatcgttct tgatcgcttt cacattgtac aacatcttag
      541 ccgtgctatg agtcgtgtgc gtgtccaaat catgaatcag tttcatcgaa aatcccatga
      601 acacaaggct atcaagcact actggaagct catacaacag gatagccgta aactgagtga
      661 taagcgattt tatcgtccta cttttcgtat gcacttaacc aataaagaga ttttaaacaa
      721 gcttttgagt tattcggaag acttgaaaca ccactatcag ctctatcagc tcttgctttt
      781 tcacttccag aataaggaac cagagaaatt tttcgaactt atcgaggaca atcttaagca
      841 ggttcatcct atttttcaga ctgtctttaa aaccttcctc aaagataaag aaaagattat
      901 caacgccctt caactacact attctaatgc caaactggaa gcgaccaata atctcatcaa
      961 acttatcaag cgcaatgcct ttggttttcg aaactttgaa aacttcaaaa aacggatttt
     1021 tatcgctttg aacatcaaaa aagaaaggac gaaatttggg ctctataata tttgtagtgg
     1081 gtaaatcccc tatggatatt atggagctta tttttgtgta gaaaaaaagt cccatatgac
     1141 ctataatgaa aagcgacaaa acaactcatt agaaaga
//
LOCUS       DAVHSL010000113         1119 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.115, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000113 DAVHSL010000000
VERSION     DAVHSL010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.115"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(1..94)
                     /locus_tag="VVR39_002189"
                     /pseudo
     CDS             complement(1..94)
                     /locus_tag="VVR39_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(552..950)
                     /locus_tag="VVR39_002190"
     CDS             complement(552..950)
                     /locus_tag="VVR39_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031566.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          339 a          217 c          170 g          393 t
ORIGIN      
        1 agtgtggata gtttgaggag cttttccaag cagagaggca atttctctat ttgatttccc
       61 tttgttcgcc ttttgtagta taatggtttt gcatctctgt gcctttcttg tgtttgtggt
      121 tgaacaacaa gtataacaca gaggtgtttt cttatgccta caagagcttt cattatttcc
      181 attttctttc ggatttcact ctattctgaa aaacttgtgt atatttactg aagctagcaa
      241 gtcttacctg taaatttaat gaaagcaaca caaaatccga gaggggaatc tcggattaat
      301 gtcaatttaa aaagatagag agtttttagt ttaaataaat tgttttaaaa tatcaacaac
      361 atcacttctt ttcttaacct gataagcctt gattcctaat tttggagcta cgattatatt
      421 gtcctcaata tcgtctagaa agacacaatt tctaggttat aactggtatt tatcgatagt
      481 tactcatata catcagtcca cctccatact tatgtgcgag cctctctttg tattatacct
      541 ccatactcac cttacagatt cttttggtaa taatatcttt gcctaatgta gagatagtct
      601 tgcaaagaaa aaacttcctt gtagccatgt ttctgataaa agtccggtgc ctggaactga
      661 taagtattga caaaggcaaa acaacaattt cgattcttag cttcactttc tgcctgttgc
      721 aatagttttg aaccgattcc ttgccctcgc agttcctctt ttacaaacaa atactcgatt
      781 tctagccaat ttccaaaagt ctctgctatc aaacccgcaa ggagattgcc cttttcatct
      841 tcgacataaa gattaagtgg ctcactttca gcctcttccc tttttgaacg gttataaaca
      901 cgaatcagat tccctatttc ttgcgattta tgtgattcct tattttccaa tctaaagtat
      961 aatgaaatga aataaaacat gcgcaaatcg attaaggaat ttaatctaat ttctaataat
     1021 gtcttagaaa tcaaagttta ctattttaac ttcaatgcac tatacatcta atactcaatg
     1081 aaaatcaaag agcaaactag gaaactagcc gcaggttgc
//
LOCUS       DAVHSL010000114          983 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.116, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000114 DAVHSL010000000
VERSION     DAVHSL010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.116"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            186..>983
                     /locus_tag="VVR39_002191"
     CDS             186..>983
                     /locus_tag="VVR39_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031567.1"
                     /translation="MIELKIGKPSFGFLPYESHIEGILTGNNLNKIDYYLSMLDMEAI
                     CLQYGNKRIYDFFIGRNIQCNNIYREYSSRIDLSSEEALIPFLVDALAKGSFCYLSVD
                     TFCINKYISYKKEHIVHSPLVSGIDLDRNLIKISDFFDFTNYGIVWVPINEFIKGYFA
                     IQKVVEEGDIEETENWILKIEKINICKNKTEICDRMAINKVFKGYVLGSEEVKDSMDT
                     FSYINYRLANHKVFQKQSIVEQNLSVTGIKVYEYLKLYIEESIKEPQV"
BASE COUNT          375 a           83 c          181 g          344 t
ORIGIN      
        1 aataaattgt taaaaaggac gaattcatct tggttagtct ctaaatttat attattgcgt
       61 taatcaggta taagtttttg cataatataa gaatagttgt gaattaaagc aggaatgatg
      121 acagaaatta tgtcaatttg agtttagttc gatgaaagta aatttatatt aggagattta
      181 taaaaatgat tgaattaaag attggaaaac caagttttgg ctttttgccc tatgaatcac
      241 atattgaagg aattcttaca ggaaataacc taaataaaat tgattattat ttatccatgc
      301 tggatatgga agcgatatgt cttcaatatg gtaataagag aatttatgat tttttcattg
      361 gaagaaatat acaatgtaat aatatataca gagagtattc gtcacgtata gatttatcta
      421 gtgaggaagc tttaatccct tttttggttg atgcgttagc taaaggttct ttttgttatt
      481 tatcagtaga tacattctgt attaataagt atattagtta taaaaaggaa catattgtgc
      541 attcaccttt ggtttcagga attgatttag atagaaacct gataaaaata tctgactttt
      601 ttgattttac aaattatgga attgtttggg ttcctataaa tgagttcatt aaaggatatt
      661 ttgcaattca aaaggtggtg gaagaaggtg atattgaaga aacagaaaac tggatactga
      721 aaatagaaaa aataaatata tgtaaaaata aaacagaaat ttgtgataga atggcgataa
      781 ataaagtttt taaaggctat gttttgggtt cagaagaagt gaaggattca atggatacat
      841 ttagttatat aaattatagg ttagctaatc ataaggtttt tcagaaacag agtatagtag
      901 agcaaaatct tagtgtgaca ggaataaaag tatatgaata tttgaaactt tatattgaag
      961 aaagtattaa agaacctcaa gtt
//
LOCUS       DAVHSL010000115          951 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.117, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000115 DAVHSL010000000
VERSION     DAVHSL010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.117"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            46..951
                     /locus_tag="VVR39_002192"
                     /pseudo
     CDS             46..951
                     /locus_tag="VVR39_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          313 a          204 c          167 g          267 t
ORIGIN      
        1 gacctataat gaaaagcgac aaaacaactc attagaaaga atcatatgga acaattacat
       61 tttatcacaa aactgctcga tattaaagac ccaaacatca agattctaga tatcatcaat
      121 aaagatacac acaaagaaat catcgccaaa ctggactacg acgccccatc ttgccctgag
      181 tgcggaaacc aattgaagaa atatgacttt caaaaacctt ctaaaattcc ttatcttgaa
      241 acgactggta tgcctactag aattctcctt agaaagcgtc gattcaagtg ctatcactgt
      301 tcaaaaatga tggtcgctga aacttctata gtcaataaga atcaccaaat ccctcgtatc
      361 atcaaccaaa agattgctca aaagttaatt gaaaagaatt ctatgaccga tattgcccat
      421 cagctggcca tttcaacttc aactgtcatt cgaaagctca atgacttcca ctttgagtgt
      481 aattttagaa atctgcctga gattatgtcc tgggacgttg aaacagtccg gggagtgact
      541 gtttcaatcg ggagatggag atgagcttta ttgcgcaaga ttttgaaaag ctcgatatca
      601 tcactgttct tgagggtaga atacaagctg tcatccgaga tcattttctt aagtatgata
      661 gagccgtccg atgtcgcgtc aaaatcatta ctatggatat gtttagccct tactatgact
      721 tggctaaaca gcttcgcttt caaatttcta ggctcaggct gaaacagtct cccagactgt
      781 ttcactcccg aatgctaaaa tcgttcttga tcgctttcac attgtacaac atcttagccg
      841 tgctatgagt cgtgtgcatg tccaaatcat gaatcagttt gaacgaaaat ctcatgaata
      901 caaggctatc aagcgttact ggaaactcat ccaacaggat agtcgtaaat t
//
LOCUS       DAVHSL010000116          897 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.118, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000116 DAVHSL010000000
VERSION     DAVHSL010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.118"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..416
                     /locus_tag="VVR39_002193"
                     /pseudo
     CDS             1..416
                     /locus_tag="VVR39_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(449..658)
                     /locus_tag="VVR39_002194"
                     /pseudo
     CDS             complement(449..658)
                     /locus_tag="VVR39_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(824..897)
                     /locus_tag="VVR39_002195"
     tRNA            complement(824..897)
                     /locus_tag="VVR39_002195"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(861..863),aa:Asn,seq:gtt)
BASE COUNT          292 a          179 c          157 g          269 t
ORIGIN      
        1 caagaagaat caccaaatcc ctcgtattat caaccaaaag attgctcaaa agttaattga
       61 aaagatttct atgaccgaca ttgatcatca gttgtctatt tcaacttcaa ctgtcattcg
      121 caagatcaat gattttcact ttgagcatga tttttcgcgt cttcctgaga ttatgtccta
      181 ggacgttgaa acagtccggg gagtgactgt ttcaatcggg agatggagat gagctttatt
      241 gctcaggact ttgataaact caatatcata actgttcttg agagcagaac acaagccatc
      301 atccgaaatc ccatggatac aaggctatca agcgctactg gaaactcatt caacaggata
      361 gtcgtaaact gagtgataaa catttttatc gtcctacttt tcgtatgcac ttgacaaaga
      421 accgaaaaat gtctcgcctc taatatagtc aattgaaaca agaacaagac aaaagagcct
      481 cgtaaaaggt attgcaactt ggtaatacct ttttgaggtg ctttttgata tgagcccatg
      541 ttttcttaat aggattgtac tcaggtgagt agggaggaag aggtaaaagt tcatgcccaa
      601 actcctcgca taaaagttct agcttaccca ttctatggaa tcttgcattg tccataatat
      661 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga attcgatttt
      721 actgtcctga tcgatttgtc ctattcttat ttcattttac tataacacga aatagattat
      781 tattacataa caaaaaagag gtctaaacct cttaactaaa ttactccgcc agtaggactc
      841 gaacctacga catcatgatt aacagtcatg cgctactacc aactgagcta tggcgga
//
LOCUS       DAVHSL010000117          851 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.119, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000117 DAVHSL010000000
VERSION     DAVHSL010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.119"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            <1..>851
                     /gene="phtB"
                     /locus_tag="VVR39_002196"
     CDS             <1..>851
                     /gene="phtB"
                     /locus_tag="VVR39_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU6031568.1"
                     /translation="SRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWV
                     PDSRPEEPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVS
                     RYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDREFYNKAYDLLARIHQD
                     LLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLGKPNAQITYT
                     DDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAA
                     QAYAKEK"
BASE COUNT          277 a          183 c          180 g          211 t
ORIGIN      
        1 caagtcgaac cgccagaggt gtagctgtcc ctcatggtaa ccattaccac tttatccctt
       61 atgaacaaat gtctgaattg gaaaaacgaa ttgctcgtat tattcccctt cgttatcgtt
      121 caaaccattg ggtaccagat tcaagaccag aagaaccaag tccacaaccg actccggaac
      181 ctagtccaag tccgcaacct gcaccaaatc ctcaaccagc tccaagcaat ccaattgatg
      241 agaaattggt caaagaagct gttcgaaaag taggcgatgg ttatgtcttt gaggagaatg
      301 gagtttctcg ttatatccca gccaaggatc tttcagcaga aacagcagca ggcattgata
      361 gcaaactggc caagcaggaa agtttatctc ataagctagg aactaagaaa actgacctcc
      421 catctagtga tcgagaattt tacaataagg cttatgactt actagcaaga attcaccaag
      481 atttacttga taataaaggt cgacaagttg attttgaggc tttggataac ctgttggaac
      541 gactcaagga tgtctcaagt gataaagtca agttagtgga agatattctt gccttcttag
      601 ctccgattcg tcatccagaa cgtttaggaa aaccaaatgc gcaaattacc tacactgatg
      661 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
      721 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      781 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      841 ctaaagagaa a
//
LOCUS       DAVHSL010000118          830 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000118 DAVHSL010000000
VERSION     DAVHSL010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.120"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            21..830
                     /locus_tag="VVR39_002197"
                     /pseudo
     CDS             21..830
                     /locus_tag="VVR39_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVHSL010000119          817 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.121, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000119 DAVHSL010000000
VERSION     DAVHSL010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.121"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            150..>817
                     /locus_tag="VVR39_002198"
     CDS             150..>817
                     /locus_tag="VVR39_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6031569.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAKQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQIC"
BASE COUNT          290 a          156 c          122 g          249 t
ORIGIN      
        1 atacctctta ttaagctcat tttaaaatta cgttaacttt tttcacaaat ttatttcgac
       61 tttctttttt actttttaca ttgctatgat acaatatttt taacaagatt ttattgtttg
      121 ttaacttttt tcacagaaag gagaaaatca tgcgttatga tttcggaaag gtctataaag
      181 aaatacgtga gtcaaagggg ctgacccaag aagaggtctg tgggggtgtt ctctcaagaa
      241 ccagcttatc aaaaatcgaa agtggcaaga caaccccaaa atatgaaaat atggaatttc
      301 ttctccgtca aatcaatatg agttttgaag agtttgaata tatctgtcaa ctttatcaac
      361 caagtcaacg cacagagatt atgcaaacct atctcaatat gcgttccatt atcgggacca
      421 gcgatcttgt caatttattt caaaaatgcc aagactacct caagacccac cacgatctcc
      481 ctatagaaga aatcagagat atgcttgaag ttgttattta tctccgtcaa cacggggcag
      541 gggaactatc aaaacacgca aaacaggttg tcaaaaaact ttggaaaaaa attgaaaaac
      601 aagatacatg gtatgagagt gatctaaaaa tcctcaatac cattcttttc agttttccca
      661 ttgaatacct ccatctcatc actggaaaaa tattgcaacg cctagaagtc tataaaaact
      721 atcaacattt atatgacttg cgaatgacaa ttctattaaa cctttccaca ctctatctat
      781 acaatcaaga taaaaacatg tgtaagcaaa tctgcta
//
LOCUS       DAVHSL010000120          763 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.122, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000120 DAVHSL010000000
VERSION     DAVHSL010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.122"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            251..727
                     /locus_tag="VVR39_002199"
                     /pseudo
     CDS             251..727
                     /locus_tag="VVR39_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
BASE COUNT          269 a          120 c          135 g          239 t
ORIGIN      
        1 ttatctacaa cctcaaaact gtgttttgag taacctgcgg ctagcttcct agtttgctct
       61 ttgattttca ttgagtatta gaacagaaaa atgcttggag tatttgtttg tgtgtttgtt
      121 tttatataac aaactataaa cacaacaaaa atataaaaaa agagacaaaa aagaacagaa
      181 agtaattaac aacgatttca tatagtgtta tacttatagc ataaagttaa tggaaagaag
      241 ggaaaacctt atggtattag attatttctt tgacaaaaac cttgtgtttt gcttagaagc
      301 ggataatcaa gaataactct ttgatcaggt agcaagcttg ttggaagaac gagaaattgt
      361 cactcctact tatcgtgaag ccttgatcac gcgtgaaaag tcatttccaa ctggtttaga
      421 tatggaattt ctaggaaagg acttgccaaa tgtagcgatt cctcacacag atattgttca
      481 taatctagct gagaaagtgg tggttgttcg attagaaaaa ccagtaactt ttcacaatat
      541 gatagctcct gataaggaag tagaagtatc cctactcttc tttatcatta acaattcaag
      601 ttcaagtcaa acaaatattc tggctcagtt gatggacttt ttcacaggaa atggacatct
      661 tgaagaccta tcaaaaattt ccgaaccaga agccctttat gcttatatag atgaagcaat
      721 cgcttaatct tgtctattaa aaaataaaat cggaggaagt cta
//
LOCUS       DAVHSL010000121          715 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.123, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000121 DAVHSL010000000
VERSION     DAVHSL010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.123"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>715)
                     /locus_tag="VVR39_002200"
     CDS             complement(<1..>715)
                     /locus_tag="VVR39_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6031570.1"
                     /translation="EYAFTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAV
                     RCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKS
                     HEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQ
                     LLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKRNAFGFRNFEN"
BASE COUNT          217 a          120 c          150 g          228 t
ORIGIN      
        1 agttttcaaa gttccgaaaa ccaaaggcat tgcgcttgat aagtttgatg agattattgg
       61 tcgcttccaa tttggcgtta gaatagtgta gttgaagggc gttgacgatt ttctctttgt
      121 cctttagaaa ggttttaaag acagtctgaa aaagaggatg aacctgcttt agattgtcct
      181 caatgagtcc gaaaaatttc tccggttcct tattctgaaa gtgaaacagc aagagttgat
      241 agagctgata gtgatgtttc aagtcttgtg aatagctcaa aagcttgttt aaaatctctt
      301 tattggttaa atgcatacga aaagtagggc gataaaaatg tttatcgctg agtttacgac
      361 tatcctgttg tatgagcttc cagtagcgct tgatagcctt gtattcatga gactttcgat
      421 ccaattgatt catgatttga acacgcacac gactcatagc acggctaaga tgttgtacaa
      481 tgtgaaagcg atccaacacg attttagcac atgggaaaag ttgtctagct aagtcatagt
      541 aaggactaaa catatccata gtaataattt tgacgcgaca tcggacggct ctatcatatt
      601 taagaaagtg atttcgaatg atagcttgtg ttcttccctc aagaacagtg atgatattga
      661 gattgttaaa atcttgcgca atgaagctca tctttccctt tgtaaaagca tactc
//
LOCUS       DAVHSL010000122          634 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.124, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000122 DAVHSL010000000
VERSION     DAVHSL010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.124"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            1..634
                     /locus_tag="VVR39_002201"
                     /pseudo
     CDS             1..634
                     /locus_tag="VVR39_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          190 a          135 c          111 g          198 t
ORIGIN      
        1 tgttcaaaaa tgatggttgc tgagactccc ctggtaaaga aaaatcacca aatccctcgt
       61 atcatcaacc aaaaaattgc tcaaaagtta attgaaaaaa tttctatgac tgatattgcc
      121 catcagcttt ccatttcaac ttcaactgtc attcgcaagc tcaatgactt tcactttgag
      181 catgattttt ctcggcttcc aaagattatg tcttgggatg agtatgcctt cactaaggga
      241 aagatgagtt tcattgcgca agattttgat aatcttaata ttatcactgt tcttgaaggc
      301 agaacacaag ctgtcatccg aaatcacttt cttcgctacg atagagccgt tcgttgtcaa
      361 gtgaaaatca ttacgatgga tatgtttagt ccttactatg acttggctaa acagcttcgc
      421 tttcaaattt ctaggctcag gctgaaacag tctcccagac tgtttcactc ccgaatgcta
      481 aaatcgttct tgatcgcttt cacattgtac aacatcttag ccgtgctatg agtcgtgtgc
      541 gtgttcaaat tatgaatcag tttgaacgaa aatctcatga atacaaggct atcaagcgtt
      601 actggaaact catccaacag gatagtcgta aact
//
LOCUS       DAVHSL010000123          525 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.125, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000123 DAVHSL010000000
VERSION     DAVHSL010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.125"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(110..>525)
                     /locus_tag="VVR39_002202"
     CDS             complement(110..>525)
                     /locus_tag="VVR39_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031571.1"
                     /translation="TSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDSSTLIKNEV
                     RMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLYA
                     YSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          139 a          113 c          106 g          167 t
ORIGIN      
        1 gtcagtttta ctttctgctg ttccagtatc gtttttcctc gctagatttc ctcaaaaggg
       61 cagactcctc ccttggtgcg tcacacgatt ttttcatctc gactgttctt taatgcatca
      121 ttaacgacgc ttttcttcta ggtggttcat aaggaacagg aagattcagg ttgacttttc
      181 taatcctaga ataaagtgct gaaaacaatt cggaataggc atagagacta gacaatttga
      241 ggagctgctt gcgtcctgtt cgaacacatt ttcctaccac gtgaagaaaa agatggcgga
      301 agcgtttgat tgttaaagtt tggaagtcac ctccagctag atgtttgaga aaaagataga
      361 gattgtaggc gatacagctc atcatcatac gaacttcgtt tttgattaag gttgaactat
      421 ccgttttatc gccaaaaaat ccctccttca tctccttgat gaaattctcg gcttgaccac
      481 gtccacgata aagctgaaac tggtcttggc ttgttccact cgtca
//
LOCUS       DAVHSL010000124          262 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.127, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000124 DAVHSL010000000
VERSION     DAVHSL010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.127"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..244)
                     /locus_tag="VVR39_002203"
     CDS             complement(<1..244)
                     /locus_tag="VVR39_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031572.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTD"
BASE COUNT           83 a           44 c           56 g           79 t
ORIGIN      
        1 agtccgttcc atagcctgtt aacagttgaa agaggaactg gacaaggata tctgaatccg
       61 aataacgaca gtagcggcgt tggtcattcg ttactaaata cttagaaatc cgctctttta
      121 gtttcaactg ggaaaaaagt tcctgaaaaa agataagacc accatactgg gttaaatgac
      181 ctccatcgaa agatagttgg taaaaagact tgttttggaa gtgatgattt ggtaaactgt
      241 tcatgtgagt ttcctttctt tt
//
LOCUS       DAVHSL010000125          253 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.128, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000125 DAVHSL010000000
VERSION     DAVHSL010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.128"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>253)
                     /locus_tag="VVR39_002204"
     CDS             complement(<1..>253)
                     /locus_tag="VVR39_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031573.1"
                     /translation="LEGGQLASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQL
                     NQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEG"
BASE COUNT           77 a           50 c           63 g           63 t
ORIGIN      
        1 cccctcgaaa gcataaagag gatgatagcc atgagcacga tagtgggcgt tataagcaac
       61 accttcttgc ttgccataag ttgtgaaatg ggtagaatcg atatctacaa tgagttggtt
      121 tagctggtga aactgtaaaa agaattcgac caattcaagg ttgaggcatc gcaaactatg
      181 gactgtttcc tcgtcagttc tggaaagaaa acgggataag gttggctgtg aagcaagctg
      241 ccctccttcc aac
//
LOCUS       DAVHSL010000126          236 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.denovo.129, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000126 DAVHSL010000000
VERSION     DAVHSL010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.denovo.129"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>236)
                     /locus_tag="VVR39_002205"
     CDS             complement(<1..>236)
                     /locus_tag="VVR39_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6031574.1"
                     /translation="RMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFG
                     LIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLP"
BASE COUNT           69 a           30 c           54 g           83 t
ORIGIN      
        1 agggtagttg aagggcgttg acgattttct ctttgttctt tagaaaggtt ttaaagacag
       61 tctgaaaaat aggatgaacc tgcttcagat tgtcctcaat gagtccgaaa aatttctcag
      121 ggtctttgtt ctgaaagtga aaaagtaaga gttgatagat ctgatagtgg tgtttcaagt
      181 cttctgaata gcttaaaatc ttgtcaagaa tttctttatt tgttaagtgc atgcga
//
LOCUS       DAVHSL010000127        22776 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.guided.032, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000127 DAVHSL010000000
VERSION     DAVHSL010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.guided.032"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            81..782
                     /locus_tag="VVR39_002206"
     CDS             81..782
                     /locus_tag="VVR39_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6031575.1"
                     /translation="MTIKLDFRTKLFMTIVLSYVMVLGNIQVKYFLQALIISVIPIVL
                     LINTKHTRVAIIGMATLVFVYGADRFLMKLEYSPLVAILLILVMVVKKILPAFLMGKY
                     TILTSNVGESIYSLKKMKCPDEIAIPLTVMVRFFYAARIDYSQIKKAMRLRGLTLKKL
                     IKNPILLFEYRLVPLLMCLSKTADDLTVSAMTKGLAVNQKRTSISESRIGGIDCIFFV
                     IMVWAIYLYIRGKYA"
     gene            775..1332
                     /locus_tag="VVR39_002207"
                     /pseudo
     CDS             775..1332
                     /locus_tag="VVR39_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844950.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            1665..1979
                     /locus_tag="VVR39_002208"
     CDS             1665..1979
                     /locus_tag="VVR39_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6031576.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            1995..2381
                     /locus_tag="VVR39_002209"
     CDS             1995..2381
                     /locus_tag="VVR39_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6031577.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            2410..3795
                     /locus_tag="VVR39_002210"
     CDS             2410..3795
                     /locus_tag="VVR39_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6031578.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            3798..3950
                     /locus_tag="VVR39_002211"
     CDS             3798..3950
                     /locus_tag="VVR39_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6031579.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            3973..5178
                     /locus_tag="VVR39_002212"
     CDS             3973..5178
                     /locus_tag="VVR39_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6031580.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            5221..5442
                     /locus_tag="VVR39_002213"
     CDS             5221..5442
                     /locus_tag="VVR39_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031581.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            5559..6056
                     /locus_tag="VVR39_002214"
     CDS             5559..6056
                     /locus_tag="VVR39_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6031582.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            6031..6537
                     /locus_tag="VVR39_002215"
     CDS             6031..6537
                     /locus_tag="VVR39_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6031583.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            6521..8968
                     /locus_tag="VVR39_002216"
     CDS             6521..8968
                     /locus_tag="VVR39_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6031584.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            8971..11148
                     /locus_tag="VVR39_002217"
     CDS             8971..11148
                     /locus_tag="VVR39_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6031585.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYDPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            11145..12146
                     /locus_tag="VVR39_002218"
     CDS             11145..12146
                     /locus_tag="VVR39_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6031586.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            12143..13075
                     /locus_tag="VVR39_002219"
     CDS             12143..13075
                     /locus_tag="VVR39_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6031587.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            13320..13436
                     /locus_tag="VVR39_002220"
     CDS             13320..13436
                     /locus_tag="VVR39_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6031588.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            13452..15371
                     /gene="tet(M)"
                     /locus_tag="VVR39_002221"
     CDS             13452..15371
                     /gene="tet(M)"
                     /locus_tag="VVR39_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6031589.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDYLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            15490..15657
                     /locus_tag="VVR39_002222"
     CDS             15490..15657
                     /locus_tag="VVR39_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6031590.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(15717..16070)
                     /locus_tag="VVR39_002223"
     CDS             complement(15717..16070)
                     /locus_tag="VVR39_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6031591.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            16575..16997
                     /locus_tag="VVR39_002224"
     CDS             16575..16997
                     /locus_tag="VVR39_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6031592.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            16994..17224
                     /locus_tag="VVR39_002225"
     CDS             16994..17224
                     /locus_tag="VVR39_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6031593.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            17685..17888
                     /locus_tag="VVR39_002226"
     CDS             17685..17888
                     /locus_tag="VVR39_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU6031594.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            17970..19187
                     /locus_tag="VVR39_002227"
     CDS             17970..19187
                     /locus_tag="VVR39_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6031595.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            19365..20210
                     /locus_tag="VVR39_002228"
                     /pseudo
     CDS             19365..20210
                     /locus_tag="VVR39_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844950.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            20244..21989
                     /locus_tag="VVR39_002229"
     CDS             20244..21989
                     /locus_tag="VVR39_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031596.1"
                     /translation="MKEKSPTAILWELAHDEHPKLKTSVFIASIGVLAGIVPYIAASR
                     ILVYLVNGIEDSKVYLMWLGIGLLSYALKSILYSLALSVSHKATFSVLKDIRLRMLDK
                     LPKMPLGEIINIPSGNLKQIIVDQVESMEKPLAHLLPEMTSNILGSLSIFIYLLFLDW
                     RMALLSLVSIPLGMFFMGLVMKNYAAQYEGSVKVSREMNSAIVEYVNGIEVIKTFNQD
                     KRSYAKYKDKVIANAKYFYEWMRSCQLPVSLSKNISPTTMITILPVGWYFYINGSLSI
                     ETFIVVIILSLGIAGPLLETMNFVDGLAKIGTIANSINSILEGKEQIHSNVDVKINKY
                     DIALQDVKFGYEEGKEILHGVSLNIEEGTTIAFVGPSGSGKSTLAKLIAGYWDINTGS
                     IKIGGYNLQEIPLKQLYSLVAFVSQDNFLFNESIRENIRMGNPSASDKEVENIAKKSG
                     CHDFIMNMEKGYDTVVGSSGSHISGGERQRISIARAMLKKSPIVILDEATSYIDPENE
                     VIIKEALSKLIQNKTVIVIAHRLSTITDVQQIFFVENGELISHGKHNELMEDCELYKK
                     MWNAHIGVKDGEIKC"
     gene            21983..>22776
                     /locus_tag="VVR39_002230"
     CDS             21983..>22776
                     /locus_tag="VVR39_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031597.1"
                     /translation="MLSALKKILDFSGDEKKNIYHSIWVSFLFAIFHMLQISAIYFIV
                     KAVSEKDMSMTPAWIALILLVVSIVGRSIANYYSQLQQCHASYFMVANKRISIGEMFK
                     KIPMGFFNGNNGGEVVGISTTVLEDVENTAAMVMVNTLSGFINTIIFTLMILIFEWRI
                     GFIVTVGSLLYLVILSKMEKKSREVLPKRQMASAKLVDTVLEQIGGMSVIKSFNLTGK
                     GDEKVRGAIENTRKTNLDCEKLFTPYTIVQNILLDLFSILIIGAGI"
BASE COUNT         7629 a         3801 c         4673 g         6673 t
ORIGIN      
        1 tgtagtatag gtatggcttt cctaaaaaaa cattttaaaa aggctggtat ggaaaaataa
       61 ggattcataa ggagttaagg atgacaatca aacttgattt tcgtacaaaa ctttttatga
      121 caatagttct ttcatatgtg atggttttag gcaatattca agtaaagtat ttcttgcaag
      181 cccttataat atccgtaatt ccgatagtgc ttttaataaa tacaaaacat acaagagtag
      241 ctattattgg gatggctact cttgtgttcg tttatggtgc tgatagattt ttaatgaaat
      301 tagaatacag tcccttggta gcgattttac tgatattagt aatggttgtt aagaaaatac
      361 ttcccgcatt tttaatgggg aaatatacca tactcacatc aaatgtaggg gaaagtattt
      421 attcattgaa aaaaatgaaa tgtcccgatg aaatagcaat accattgact gtgatggttc
      481 gtttctttta tgccgcaagg attgattata gccagataaa aaaagccatg cgtttgagag
      541 gactaacgct taaaaagtta ataaaaaatc caattctatt atttgaatat agattagtgc
      601 cactattgat gtgtttgtct aagacggcag atgatttaac agtatccgca atgacaaaag
      661 ggttagctgt taatcaaaag cgaacaagta ttagtgaatc acgcattggt ggcattgatt
      721 gcatattttt tgtgataatg gtatgggcaa tctatttata tataaggggt aagtatgctt
      781 agtttacaaa atttagtatt aaagtttgat ggagaaagca tattagaaaa tgtaaatcta
      841 aatttcaaac ccggagaggt aactgttata acgggacact caggtacggg gaaaagtagt
      901 ttgttaaaag taataaacgg cattattccc gaatatgatt gtggagatgt aaaaggagat
      961 gttttataca aggacaaatc tttattaggg atgagtatat tagaacgatc caagtttata
     1021 tctacagtgt ttcaaaatcc taaaacacag ttttattgta tcaattccac agatgaattg
     1081 gcttttcaat tagaaaatag atgtatagaa agaaatttaa ttttagataa aatacactat
     1141 tattcagatg ttttaggtag taaagatttg ttagacaaga atatttttga actgtccggt
     1201 ggagagaagc agttaattgc tataactgct agtggaattt cagaaaatga aattattctt
     1261 ttagatgaac catcttcatc tttggattat gaatcaatta agaacttaaa aagagctatt
     1321 attgagctaa aaatagcata aaaatctagt tatccgcata aaaactggac ttatcacact
     1381 ttatcaaggt caaaaccact caatttacta ctaatttact acttatgaat gagctttgat
     1441 acgacgattt atccttgaaa agtgaagata taaagatact tccaataaaa tttgaatatt
     1501 taataggtag acacttcaaa aaatgaggtg tctatttttt tacccgattt tgaaaggaag
     1561 tgaacttatg aaaacaaaaa atcaagaatc aaaaggtcgt tccccactct ttaagaccat
     1621 caaacattca ttcagccaat aaaaaagaaa ggataggtaa aaatatggaa cttaaatttg
     1681 tgattcccaa catggaaaaa acattcggca atttagaatt tgctggcgag gataaagtcg
     1741 ttcagcgaag aatcaacgga cggctaactg tcttatcaag aagctataat ctctattctg
     1801 atgttcaaag agcagatgat attgtggtgg tgcttcctgc tgaagctggc gaaaaacatt
     1861 tcggctttga ggaacgtgtg aagttagtca atccacgtat taccgcagag ggctacaaaa
     1921 tcggcactcg tggttttaca aattaccttt tacatgctga cgacatgata aaagaataaa
     1981 gaaagagagg aaaaatgatg agattagcaa atggcattgt attagataaa gacacgactt
     2041 ttggagaatt gaaattctct gctctacgtc gtgaagtgag aatccaaaat gaagacgggt
     2101 cggtttcaga tgaaatcaag gaacgtacct atgacttaaa atccaaagga caaggacgca
     2161 tgattcaagt aagtattcct gccagcgtgc ctttgaaaga gtttgattat aacgcacggg
     2221 tggaacttat caatcccatt gcggacaccg ttgctactgc cacctatcaa ggagcagatg
     2281 ttgactggta tatcaaggca gacgatattg tgctgacaaa ggattctagt tcattcaaag
     2341 ctcaaccaca agcaaagaaa gaaccgacac aagacaaata gtcgctaggt agaaaggaga
     2401 ctttttcgca tgaaacagcg tggtaaaagg attcgcccat ctggtaaaga tttagtcttt
     2461 cattttacga tagcgtcact cctgcctgtt ttcctgctgg ttgtcggact gtttcatgtg
     2521 aagacaatcc agcagatcaa ctggcaggat tttaacctat cacaagcaga taagattgac
     2581 attccctatt taattatcag tttcagtgtc gcaattctta tctgcttgct ggtagcgttt
     2641 gtattcaaac gggttcgcta tgatacggtt aaacaacttt accaccgtca aaaactggca
     2701 aagatgatac ttgaaaacaa gtggtatgaa tctgaacagg tcaaaacaga gggtttcttt
     2761 aaagatagtg ctggtcgtac aaaggaaaag ataacctact tccctaaaat gtattatcga
     2821 cttaaaaatg gcttgataca gatacgggtg gaaatcacgc tgggaaaata tcaagaccaa
     2881 ctcttacact tggaaaagaa attagagagt ggcttgtact gtgagctgac ggataaagag
     2941 ttaaaggatt cctatgtgga atatactttg ctctatgaca ccatagccag tcgtatttct
     3001 attgatgaag tagaagctaa agatggtaaa cttcgcttaa tgaaaaacgt atggtgggaa
     3061 tatgataagc tccctcatat gttgattgct ggtggtacag gtggcggtaa aacttacttt
     3121 atactgacac tgattgaagc cttgcttcat acagattcaa aactgtatat tcttgacccg
     3181 aaaaatgctg atcttgcgga cttaggttct gtgatggcaa atgtctacta tagaaaagaa
     3241 gacttgcttt cttgcattga aacattctat gaagaaatga tgaaacgtag tgaggaaatg
     3301 aagcagatga agaactataa gactggcaaa aattatgctt acttaggtct cccggcacac
     3361 ttcttaatct ttgatgaata cgtcgctttc atggaaatgc tgggaacaaa agaaaacacc
     3421 gcagttatga ataagctgaa acagattgtc atgttaggtc gtcaagctgg cttctttcta
     3481 atactggctt gtcaacgtcc agacgcaaaa tatttaggcg acggaatccg tgatcagttt
     3541 aatttcagag tggctttagg tcgtatgtct gaaatgggct atggcatgat gtttggcagt
     3601 gacgtacaaa aggatttctt cttaaagcga atcaaaggtc gtggctatgt tgatgtagga
     3661 acaagtgtca tatcagagtt ttatactccc cttgtaccaa aaggatatga tttcttggag
     3721 gaaattaaaa agttatccaa cagcagacag tccacgcagg cgacgtgcga agcggaagtc
     3781 gcaggtgtgg actgatcttg ctggctggtg tggcaatagc cacgccagca cttaaccccc
     3841 cgtatctaac aggggggtac aaatcgacag gaaacagtca aaaaaacatt agaaaatcct
     3901 ttggttacaa gggatttaca aaatttcagc gtatgtcaaa tgggctttaa aagttgacat
     3961 acgccttttt gattggaggg atttttactg aatgaacaaa cttggttaca gcatttaaaa
     4021 gaaaaacgct tggcttatgg actatctcaa aaccgtttag ctgttgcgac tggtattaca
     4081 aggcagtatc taagcgatat tgaaacagga aaagtcaagc catcagagga tttacagcag
     4141 tccctttggg aagctctgga acgcttcaat cccgacgctc cccttgaaat gctgtttgat
     4201 tatgtaagaa ttcgctttcc gacaacagac gtacagcagg tggtcgaaaa catcttacaa
     4261 ctgaaactgt cctattttct tcatgaggac tatggtttct attcttattc agagcattat
     4321 gctttaggcg acatattcgt cctttgctcc catgaactgg acaaaggagt tctggtggaa
     4381 ttgaaaggtc gtgggtgcag acaatttgaa agctatcttc tggcacaaca aagaagctgg
     4441 tatgagttct ttatggacgt tttggtggct ggcggtgtga tgaaacgcct tgaccttgcc
     4501 attaacgata agacagggat tttaaatatc cctgtactca ctgaaaagtg ccaacaggaa
     4561 gaatgtatct ccgtcttccg cagttttaaa agctatcgca gtggcgaact ggtacgcaaa
     4621 gaggaaaagg aatgtatggg aaacaccctc tatatcggtt cattacaaag tgaagtttat
     4681 ttctgtatct atgaaaagga ctacgagcag tacaagaaaa atgatattcc cattgaagac
     4741 gcagaagtaa aaaaccgttt tgagattcga ttgaaaaatg agcgtgccta ttatgcagtc
     4801 cgtgatttac tcgtctatga caatccagag cataccgcct ttaaaattat caatcggtat
     4861 atccgttttg tagataaaga cgattccaaa cctcgttctg attggaaact gaatgaagaa
     4921 tgggcttggt ttattgggaa caatcgtgaa cgattaaaac taaccacaaa accagagcct
     4981 tactccttcc aaaggacgct gaactggcta tctcatcaag ttgccccgac cttaaaggtt
     5041 gcgattaaac ttgatgaaat caaccagacg caggttgtaa aagacattct cgaccatgcg
     5101 aaactgacag accgacacaa gcagattttg aagcaacagt cagtaaaaga acaggacgtg
     5161 ataacaacaa aaaaataact caaatacaaa ttcattgaat atagagagga gaacattttt
     5221 atgaattttg gacaaaacct ttataactgg tttctatcaa acgctcaatc actggtgctt
     5281 ttagcaatcg ttgtgattgg cttgtatctt ggcttcaagc gtgagtttag caaactgatt
     5341 ggctttttaa ttattgcgat tattgcggtt ggcttagtct tcaacgctgc tggagtaaaa
     5401 gacattttac tagagctatt caatcgcatt attggtgctt aaataaaacc gttcttttgt
     5461 ggaatataag tggttttctt atgttccgca aaggaatggt acaccaaacg aagtgcggta
     5521 gggatttttg aatctctaca aagaaaggac gtgaatatat ggacgatatg caagtctata
     5581 ttgcgaattt aggcaaatac aatgagggcg aattggtcgg tgcgtggttt acctttccca
     5641 ttgactttga ggaagtcaaa gagaaaatcg gcttgaatga tgaatatgag gaatacgcca
     5701 ttcatgacta cgagttaccc tttacggttg acgaatacac ttccattggc gaactcaatc
     5761 gactatggga aatggtatcg gaattacccg aagaattaca atcggagcta tctgctctgc
     5821 tcactcattt ttcaagcatt gaagaactaa gcgaacatca agaggatatt atcattcatt
     5881 ccgattgtga tgatatgtat gacgtggcac gctactacat tgaagaaacg ggtgctttag
     5941 gcgaagtacc agctagtctt caaaactata ttgattatca agcctatggt cgggatttag
     6001 acctttcagg aacgtttatc tcaaccaatc atgggatttt tgaaatcgtc tattaaatct
     6061 gtcggtacat tactactggc agattttcta ttttacgggg tggctcaatc agctacccct
     6121 attttttatg aaaggattga ttacatgaag aaaatacgaa gctataccag tatctggtct
     6181 gtggaaaagg tactgtattc tatcaatgat tttagacttc cgtttcccat aacctttacg
     6241 caaatgacat ggtttgtcgt gtcactcttt gcagtgatga tacttggcaa cttgccccct
     6301 ctttccatga tagagggagc atttctcaaa tactttggga ttcctgtggc tttcacatgg
     6361 tttatgtcta caaaaacttt tgatggtaaa aagccttatg gatttttgaa gtctgtcatt
     6421 gcttatgcac tgcgaccaaa gctgacctat gcaggaaaaa aagtaacgct tggcagaaac
     6481 cagccacaag aagccattac agcagttagg agtgaatttt atggcatatc caattaaata
     6541 cattgaaaac aatctcgtct ggaataaaga cggggaatgt tatgcttact atgagcttgt
     6601 tccttacaat tactcatttc taagtccaga acagaaaata caagtgcatg attctttcag
     6661 acagcttatc gcacaaaatc gtgatggcaa aattcatgct ttacaaatca gtacagaatc
     6721 cagcatacgt tctgcacaag agcgttccaa aaatgaagtc actggcaagc tcaaagcggt
     6781 tgcctatgac aaaatcgacc aacagacaga cgctttaata tccatgattg gcgaaaatca
     6841 agtgaactac cgtttcttta tcggctttaa gttgcttctc aacgatcagg agttttctat
     6901 gaaaagtctt accgttgaag caaaaaatgc tttgtctgat tttgtctatg atgtgaacca
     6961 taagctgatg ggcgattttg ttagtatgag taatgatgaa atcctgcgtt ttcagaagat
     7021 ggaaaagctc ttagaaaata aaatctctcg tcgtttcaaa atccgcaggt tagataagga
     7081 cgacttcggc tatctgattg aacaccttta cggacagaca ggcactgcct atgaagagta
     7141 tgagtaccat ctatcaaaga aaaagctgga taatgaaacg ctgattaaat actatgactt
     7201 gattaagcct actcgctgtt tggtggaaga aaaacagcga tatttgaaaa tccagcagga
     7261 agatgaaacc gtctatgtag cttactttac cattaacagc attgtcggag aactggactt
     7321 cccgtcctct gaaatcttct actaccagca acagcaattt acattcccga ttgatacgtc
     7381 aatgaatgtg gaaattgtag cgaatcgtaa agccctatct actgtccgca ataaaaagaa
     7441 agaactgaaa gacttggata accacgcttg gcaaagtgat aatgaaacca gctccaatgt
     7501 ggcggaagct ctggaaagtg tgaatgagct ggaaaccaat ttagaccaaa gcaaggaatc
     7561 tatgtacaag ctgtcttatg tggtaagggt atcagcaaat gatcttgacg aactcaaacg
     7621 tcgttgtaat gaagtgaaag atttttatga cgatttaagc gtaaaactgg tacgaccatt
     7681 tggggatatg ctcggcttac atgaagaatt tttacctgcc agcaagcgtt atatgaatga
     7741 ttatattcaa tacgtgacct ctgatttcct cgctggttta ggttttggtg ctactcaaat
     7801 gctgggggaa aatgagggga tttatgttgg ctacagctta gatactggac gcaatgtcta
     7861 tctgaaacct gctcttgcca gtcaaggggt taagggttca gtaaccaatg cgttagcgtc
     7921 ggcttttgtt ggttcgctgg gtggtggtaa atcctttgcg aataacctta tcgtctatta
     7981 tgcggtgctt tatggggcac aagcagtgat tgtagaccca aaagcagaac gtggcagatg
     8041 gaaagaaacc ttgccagaga tttcccatga aatcaatatc gtcactctga cttctgatga
     8101 gaaaaacaaa ggcttacttg acccttatgt gattatgaaa aatcccaaag attctgaatc
     8161 actggctatt gatattctga cattccttac ggggatttcc tctcgtgatg gggaacgctt
     8221 cccaatcctt agaaaagcca ttcgtgcagt aaccaatagt gaagtacgag ggttgatgaa
     8281 agtgattgag gaattacggg ttgagaatac gccactaagt accagtatag ccgaccatat
     8341 cgaaagtttt acagactatg actttgcaca tttattattc agtaatggtt atgtggagca
     8401 gtctatcagc ttagaaaaac aactgaacat tatacaggtt gcggacttgg tacttcccga
     8461 caaggaaact tcctttgagg aatataccac tatggagctt ttatccgttg ctatgctgat
     8521 tgtcattagt acctttgctt tagactttat ccatacagac cgaagcattt tcaagattgt
     8581 agatttagac gaagcatgga gctttttaca ggtagcacaa ggaaaaacac tatctatgaa
     8641 gctggttcgg gctggtcgtg ctatgaacgc tggggtatat ttcgtgaccc aaaatacaga
     8701 cgacctctta gatgaaaaac tgaaaaataa cctcggctta aaatttgcat ttcgttccac
     8761 tgaccttaac gagattaaaa agaccttagc cttttttggt gtagacccag aggacgaaaa
     8821 caatcagaag cgattgcgtg atttggaaaa cgggcaatgc cttatcagtg atttatatgg
     8881 tcgtgtcggt gtgatacagt tccaccctgt atttgaagaa ctgctccatg cctttgatac
     8941 cagaccacct gtgcgaaaag aggtgtaaat gtgaaaccat caatagtaaa cagaataaaa
     9001 tcaaactgga cgctgaaacg tctaggtaaa gtggcaatga cagtggcttt cacacttgtg
     9061 attgccattt ttcttttagc catgctggga acggtggttc aagctgcggg cttggtagat
     9121 gatacggtca atgtggcaaa tgaatacagc cgatacccac ttgaaaacta tcaactggat
     9181 ttttatgtgg ataatagctg gggctggctt ccgtggaact ggtcggacgg gattggaaaa
     9241 caggtcatgt atggactata tgccattacc aattttattt ggacaatcag tttgtatgtt
     9301 tccaatgcga caggttactt agtacaggaa gcctattcct tagacttcat ttccgctaca
     9361 gcagattcca ttggtaagaa tatgcagacc ttagctggtg tgagtgcaaa cggattttca
     9421 acagagggtt tctatgttgg attcctctta ctcttgattt tggttcttgg ggtttatgtt
     9481 gcctatacgg gactgataaa gagagaaacc acaaaggcaa ttcatgccat tatgaatttt
     9541 gtgctggtgt ttatcctatc ggcttccttt attgcctacg atcccgacta cattaaaaaa
     9601 atcaatgact tttcatcaga catcagtaat gccagtttat cacttggcac gaagattgtc
     9661 atgccccatt ccgatagtca aggcaaggac agcgtggact taatcagaga tagcctgttt
     9721 tccatacagg ttcagcaacc gtggctactg cttcaataca acagttcaga cattgaaagt
     9781 atcggtattg accgtgtgga aagcctgctc tccaccagcc cagattccaa caatggcgaa
     9841 gatagagaaa aaattgttgc ggaagaaatt gaagacagaa gcaataccaa tctaaccatt
     9901 acaaagacca ttaaccgttt aggtacagtc ttcttcctat ttgtcttcaa tattgggatt
     9961 tccatatttg tattcctatt aacaggaatc atgattttct cgcaggtact ttttatcatc
    10021 tatgctatgt ttctgcctgt gagctttatt ttaagcatga ttccatcatt tgatggtatg
    10081 tcaaaacgag ccataacaaa gctctttaat accattttga cacgagctgg aatcacattg
    10141 attattacga cagcatttag tatttcaacc atgctctata ccttatcggc tggttatccg
    10201 ttctttttga ttgcttttct acagattgtg acctttgcag gaatctactt caagctgggc
    10261 gatttaatga gtatgttttc tctacagagt aacgattctc aaagtgtggg aagtcgtgtg
    10321 atgagaaaac ctcgtatgct tatgcacgct cacatgcacc gtctacagcg gaaacttgga
    10381 cgttccatga ctactctagg ggctgggtct gccattgtta caggtaaaaa aggacagtcg
    10441 ggttcgggga gttctgcaag gacacaagca gatcactccc gaccagacgg aaaggaaaaa
    10501 tcaacacttg gaaaacgtat cggtcaaacc atcggtacag tagctgatac caaagacaga
    10561 atggtagaca ctgctagtgg tttgaaagaa caggttaaag atttgccgac caatgcaaga
    10621 tatgcagtat atcaaggaaa atccaaagta aaagagaatg tccgtgattt aaccagtagt
    10681 atttctcaaa ccaaagcgga cagagccagt ggacgcaagg aacagcagga acaaaggcga
    10741 aaaaccattg cgaagcgtcg ctctgaaatg gaacaggtca aacagaaaaa acagcctgct
    10801 tcttctgttc atgaaagacc gactacaaga caagaacaat atcatgatga acagacctca
    10861 aaacagtcta atattcagac ttcatataag gaatctcaac aagccaaaca agagcgtcca
    10921 gcagttaagt ccgatttttc aagtccaaaa gtggaacgcc aaggcaatac cgttcaagaa
    10981 aaaaccgttc aaaagccagc aacttcaacc actacagcag atagaacttc acaacgtcca
    11041 atcacaaaag aacgtccgtc tactgttcaa agagtaccac tacaaaatac aagaagtaga
    11101 ccaccaatca aaaccgccac cattaagaaa gtcggtaaga aaccatgaag ttgaaaactt
    11161 tagtgattgg tggttctgga ttattcttga tggtcttctc actgcttctg tttgttgcca
    11221 ttttattttc agatgaacag gacagcggaa tttccaatat tcattatgga ggtgtgaatg
    11281 tttccgcaga agtgctggct cataagccta tggtagaaaa atatgccaaa gaatatggcg
    11341 ttgaagaata tgtcaacata cttcttgcga ttatacaggt ggaatcgggc ggtactgcgg
    11401 aagatgttat gcagtcctcg gaatccctcg gtcttccacc taattcattg agtacagaag
    11461 aatccattaa gcaaggtgtg aagtatttca gtgaattatt agccagtagc gaaaggctca
    11521 gtgtagattt agaatcggtt atccagtcct acaattatgg tggtggtttc ttagggtatg
    11581 tggctaatcg tggaaataaa tatacctttg aactggctca aagtttctca aaagagtatt
    11641 caggtggcga aaaagtgtct taccccaatc ccatagccat acctatcaat gggggctggc
    11701 gatacaacta tggcaatatg ttttatgtgc aactggtaac gcagtatctt gtcacaacag
    11761 agtttgatga tgatacggta caagccatca tggacgaagc actgaaatat gagggctggc
    11821 gatacgttta cggtggagct tccccgacta cttcttttga ttgtagcgga ctgacacaat
    11881 ggacgtatgg aaaagctgga attaacttac cacgaaccgc acaacagcaa tatgatgtga
    11941 cccagcatat cccactatcg gaagcacaag ctggcgattt ggttttcttt cattctacct
    12001 ataacgctgg ctcttatatt actcatgttg ggatatacct tggcaataac cgtatgtttc
    12061 atgcaggcga cccaatcggt tatgccgact taacaagccc ctactggcaa cagcatttag
    12121 tgggagcagg acgaatcaaa caatgagaaa ggaagattta atgatgaaat ttagaaaaaa
    12181 tcagaataaa gaaaaacaga taccaaagga aaagaaacct cgtgtctata aggtcaatcc
    12241 tcataaaaag gttgtgattg ccttgtgggt acttttaggg cttagtttca gctttgcgat
    12301 attcaagcac tttacagcta tagatactca tactattcac gaaacaacta tcatagaaaa
    12361 ggaatacgtt gatactcatc atgtagaaaa ttttgtagag aactttgcga aagtctacta
    12421 ttcatgggag caatccgata agtccattga taatcgaatg gaaagtctaa aaggctatct
    12481 gacagatgaa cttcaagctc tcaatgttga tacagtacgc aaagatattc ctgtatcgtc
    12541 ttctgtaaga ggatttcaga tatggacggt agagccaact ggcgacaatg agtttaatgt
    12601 aacctacagt gtagaccagc tcattacaga gggagaaaat acaaagaccg tccactctgc
    12661 ttatatagtg agtgtctatg tagatggttc tggaaatatg gtactggtta agaatccgac
    12721 cattaccaac atacctaaga aatcaagtta taaaccaaaa gccattgaaa gtgaggggac
    12781 ggttgattcc attacaacca atgaaatcaa tgagttttta acgacgttct tcaagctcta
    12841 tcctacagcg acagccagtg aactttccta ctatgtgaat gacgggatat taaaaccaat
    12901 cggaaaagag tacatctttc aagaactggt aaatcctatt cacaatcgta aggataatca
    12961 agtcacggta tcgctgacag tggagtatat cgaccagcag accaaagcaa cgcaggtatc
    13021 tcaatttgat ttggtacttg aaaagaacgg gagtaattgg aagattatag aataacaaat
    13081 attggtacat tattacagct attttgtaat cacgtactct ctttgataaa aaattggaga
    13141 ttcctttaca aatatgctct tacgtgctat tatttaagta tctatttaaa aggagttaat
    13201 aaatatgcgg caaggtattc ttaaataaac tgtcaatttg atagtgggaa caaataattg
    13261 gatgtccttt tttaggaggg cttagttttt tgtacccagt ttaagaatac ctttatcatg
    13321 tgattctaaa gtatccggag aatatctgta tgctttgtat gcctatggtt atgcataaaa
    13381 atcccagtga taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg
    13441 aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa
    13501 ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg
    13561 acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc
    13621 agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag
    13681 gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc
    13741 tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta
    13801 ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt
    13861 tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta atcaaacaga
    13921 aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa caatgggata
    13981 cggtaataga gggaaacgat taccttttag agaaatatat gtccggtaaa tcattagaag
    14041 cattggaact cgaacaagag gaaagcataa gatttcagaa ttgttctctg ttccctcttt
    14101 atcatggaag tgcaaaaagt aatataggga ttgataacct tatagaagtt attactaata
    14161 aattttattc atcaacacat cgaggtccgt ctgaactttg cggaaatgtt ttcaaaattg
    14221 aatatacaaa aaaaagacaa cgtcttgcat atatacgcct ttatagtgga gtactacatt
    14281 tacgagattc ggttagagta tcagaaaaag aaaaaataaa agttacagaa atgtatactt
    14341 caataaatgg tgaattatgt aagattgata gagcttattc tggagaaatt gttattttgc
    14401 aaaatgagtt tttgaagtta aatagtgttc ttggagatac aaaactattg ccacagagaa
    14461 aaaagattga aaatccgcac cctctactac aaacaactgt tgaaccgagt aaacctgaac
    14521 agagagaaat gttgcttgat gcccttttgg aaatctcaga tagtgatccg cttctacgat
    14581 attacgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg
    14641 aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta
    14701 cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc
    14761 cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg
    14821 gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcgttt caaaatgcag
    14881 ttatggaggg gatacgctat ggctgtgaac aaggattgta tggttggaat gtgacggact
    14941 gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca gcagattttc
    15001 ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca gaattgttag
    15061 agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga gcatacaacg
    15121 atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat gaggtcattc
    15181 ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta actttcttta
    15241 caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact accggtgaac
    15301 ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat atgttcaata
    15361 aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa ataagatgaa
    15421 atatttttta ataaagattt gaattaaagt gtaaaggagg agatagttat tataaactac
    15481 aagtggatat tgtgtcctgt atgtggaaat aaaacacgat taaagataag ggaagatact
    15541 gaattaaaaa aattccccct ctattgtccg aaatgcagac aagaaaattt aattgaaata
    15601 aagcagttca aagtaactgt gattacagag ccagacgcaa agacgcagag ccgataaaat
    15661 gagattaata caatctcatt ttatcggctc tttccgttat gtatggattc ttttaattag
    15721 tcttcgatgt ttcttgcttc gttgataccg ctggctaaag attccattaa ggatagttct
    15781 ttgtctgtaa agctatccat gtatttctct atctgtaatc gtcgggtgct ttttaccaag
    15841 ttattagcag gtaagaaaaa ttcatcaacg gaaacatgaa gtaacgatac aaggtcataa
    15901 agaacttgta tgctggggtg ttgcccttta ttttcaatat tagttaagta ccgtgggtca
    15961 atttcaatca atgctcccac ttgttcacga gttaaacctc gtttcaatcg agcttcttta
    16021 atggctaaac caaaggctct aaaatcatat ttatcttctt ttttacgcat agtagaccac
    16081 ctctatacat tttattgttc ctactgaatt aaaaacaggt atagaaaaac gtgttatatg
    16141 gtttataggt ttatatttaa taaaaagcac tactaaacgc caataaaaaa aaccgttata
    16201 tggtagtgct atttacgctg ttaaaatatt gtatattact tccaaatggc ggtttgttgg
    16261 aggtcaacgt cgccatgaag tacatcatat acaataaatt tccttacatt gggttcttgt
    16321 caaaaaaagt cgtctatctg caatagataa gtacgtccac caatgtggtt ttataaatca
    16381 tatagataga ataacagaag catgtaaaca gagaaataaa tctgtttata tgcttttttg
    16441 gctattcaga acttttttac aaagtttatt tatcagtaat gcaacaaatc cccctttcac
    16501 attgggacta agagtgaaag gagataaacg agcaaggctc acttcctttc ctagacagaa
    16561 agggggtgag aaacatgaaa ccatcttctt ttcagaccac aatagaaaat cagtttgact
    16621 atatctgtaa acgtgctatg gaagacgagc gaaagaatta tatgctttat ctttcaagga
    16681 ttgcaaagcg tgaggtgtcc ttttcggatg ttggcgatta tcttgttagc cagtttgcga
    16741 caacagataa ctattcaact gactttcaga tttttacact caatgggtta tcagtaggcg
    16801 ttgaaaatga tttgttgagt gaagcattac gtgagttgcc agacaagaaa cgtgaaattc
    16861 tactgctgtt ttactttatg gacatgagcg attcagaaat tgcagacctg ttgaaattga
    16921 accgttctac tgtctatcgg catagaacca gtggactagc cttaattaaa aagtttatgg
    16981 aggaatttga agaatgaaaa cacaatatcc tatgattccc tttcctctca ttgtaaaggc
    17041 aacagatggc gataccgaag cgattaacca gattctacat cattacagag ggtacataac
    17101 gaagcgttcc ctacgactta tgaaagatga atatggcaat caaagtatgg tcgttgatga
    17161 agtcttacgt ggaagaatgg aaaccagact gattacaaag attttgtcat ttgaaattaa
    17221 gtaatatcct ctctcctttc gtggaagcgt gctaaaccat tccacgcttc ccgaacaggg
    17281 aggtttgtta ttccaccaaa gcatattgag ctttcaatgt gttttgatag gctaacgagc
    17341 cattgttctt tgaaaactga ataaaagtaa tcgaatacgt ttcgataaga aaagagccaa
    17401 cggaactaac cgccatgacc tatcttataa agatagcgag cgattcatgt tagtgatccg
    17461 agaagcaatc tttagcagga ttgcctgcaa cgacattctt atcgtgataa tgatactccc
    17521 atacagtcaa tagtccgagc gtgataaaac cgtcgcaggc aatgagtatg gctacatgag
    17581 aaccatgcag gggtggaact cccgtgagct ttgctaaagc tgttcgattg ctggtaaaac
    17641 aacttttatg aaatccaaat aagtgatttg gaaaggagga ttttatgaag cagactgaca
    17701 ttcctatttg ggaacgttat accctaacca ttgaagaagc gtcaaaatat tttcgtattg
    17761 gcgaaaacaa gctacgacgc ttggcagagg aaaataaaaa tgcaaattgg ctgattatga
    17821 atggcaatcg tattcagatt aaacgaaaac aatttgaaaa aattatagat acattggacg
    17881 caatctagcg tcgccaaagg gtcttgtata tgataaaata gtattaagtc gtatcaaggc
    17941 tctttccata aaggaaagga gcaaatgcca tgtcagaaaa aagacgtgac aataaaggtc
    18001 gaatcttaaa gactggagag agccaacgaa aagacggaag atacttatac aaatatatag
    18061 attcatttgg agaaccgcaa tttgtttact cgtggaaact tgtggctaca gaccgagtac
    18121 cagcaggaaa gcgtgattgt atctcactta gagagaaaat cgcagagtta cagaaagaca
    18181 ttcatgatgg tattgatgtt gtaggaaaga aaatgacact ctgccagctt tacgcaaaac
    18241 agaacgctca aagaccaaag gttagaaaaa acactgaaac tggacgcaaa tatcttatgg
    18301 atattttgaa gaaagacaag ttaggtgtaa gaagtattga cagtattaag ccatcagacg
    18361 ctaaagaatg ggctattaga atgagtgaaa atggttatgc ttatcaaacc atcaataact
    18421 acaaacgttc tttaaaggct tcattctata ttgctataca agatgattgt gttcggaaga
    18481 atccatttga ctttcaactg aaagcagttc ttgatgatga tactgtccct aagaccgtac
    18541 taacagaaga acaggaagaa aaactgttag cctttgcaaa agctgataaa acctacagca
    18601 aaaattatga tgaaattctg atactcttaa aaacaggtct tcgtatttca gagtttggtg
    18661 gtttgacact tccagattta gattttgaga atcgtcttgt caatatagac catcagctat
    18721 tgagagatac tgaaattggg tactacattg aaacaccaaa gaccaaaagt ggcgaacgtc
    18781 aagttcctat ggttgaagaa gcctatcaag catttaagcg agtgttagcg aatcgaaaga
    18841 atgataagcg tgttgagatt gatggatata gtgattttct ctttcttaat agaaagaact
    18901 atccaaaagt ggcaagtgat tacaacggca tgatgaaagg tcttgttaag aaatacaata
    18961 agtataacga ggataaattg ccacacatca ctccacatag tttgcgacat acattctgta
    19021 ccaactatgc aaatgcagga atgaatccaa aggcattaca gtacattatg ggacatgcta
    19081 atatagccat gacgctgaac tattacgcac atgcaacatt cgattctgca atggcagaaa
    19141 tgaaacgctt gaataaagag aagcaacagg agcgtcttgt tgcttagtag tacaaatgaa
    19201 tttactactt atttaccact tctgacagct aagacatgag gaaatatgca aagaaacgtg
    19261 aagtatcttc ctacagtaaa aatactcgaa agcacataga ataaggcttt acgagcattt
    19321 aagaaaatat aaaaagataa ttagaaattt atactttgtt tatattaaaa aaaagaaata
    19381 aaatcataat cattgtcgag catagattat tttatttgaa agacattgta gacaagctgt
    19441 gtgtaataga aaataaaact tttaaagaat acacgaaaga atattttagt gatgatttct
    19501 ttgtaagagt ttcagaaaaa cataatttaa gaaatttcaa tgaaattttt aagagtgatt
    19561 tcttaaatag acaatatgaa aaagtagata tgttacaaaa aaatactcca tcaaactttg
    19621 ttaatgaatc aataacatgt ctacatttca aaaaaacata cgataagaat acaatttttg
    19681 attttagtgt ttcttttaat accgggataa atttcattat tggacaaaac ggtgttggga
    19741 aaagtacttt tatcaattta cttatgggaa ctataaaagg caagggagaa gttttttata
    19801 agggagaaaa gctcaaaaaa cggtacgaga atatctttgc agtcatgcaa gatgttaatt
    19861 atcaactttt cacagaatct gtatggcagg aaattggaac agttacaaaa caggataatt
    19921 tgaaaaatga agccttaaga aaggtacatt tatttaataa aaaagaaatg cacccaagtt
    19981 cgttatcagg tggtgaaaaa cagagattgt tgcttgctat gtctatggta agtcaaaaac
    20041 caatcatagt gtttgatgag ccaacgagtg gactttgcaa aatgcaaatg gatattttga
    20101 ttggattttt aaatcaaatg gtagagcaag gaaaaactat tattataatc acgcatgatt
    20161 ttgaatttat aaaacaatgc gatggtgcaa tatatgaatt tttgaaatga aatgtaaata
    20221 gatagaacta tggaggtgtt gaaatgaaag aaaaaagtcc tactgcaata ttgtgggagc
    20281 ttgcacatga tgaacatcca aaattaaaga catcagtatt tatagcgagt attggtgttt
    20341 tagcggggat tgttccatac attgcggcaa gtcgcatttt agtttattta gtgaatggaa
    20401 ttgaagacag caaggtttat cttatgtggc ttggcatagg cttgctatca tatgctttga
    20461 aatcaatttt atattcttta gcattatcag tatctcataa agcgactttt agtgtactaa
    20521 aagatattcg tttaagaatg cttgataaac ttccaaagat gccattggga gaaataataa
    20581 atattccaag cggtaattta aagcaaatta tagtcgatca ggtcgaaagt atggagaaac
    20641 ctcttgcaca cttattacct gaaatgacat ccaatatatt aggctctttg agtatattca
    20701 tatatttgtt atttcttgac tggagaatgg cgttattgtc attagtttct attcctttag
    20761 gaatgttttt catgggactt gtgatgaaaa actacgctgc tcagtatgaa ggatctgtaa
    20821 aagttagtcg tgaaatgaac tcggcaattg tggagtatgt taacggaata gaagtgatca
    20881 aaaccttcaa tcaggataaa aggtcatatg caaaatataa agataaggtt attgcaaatg
    20941 caaagtattt ctatgaatgg atgagaagct gtcaacttcc tgtgtcttta tcaaaaaata
    21001 tatcgcctac tacaatgata acaatccttc cggttggctg gtatttttac atcaatggaa
    21061 gtttgagtat agaaacattt atagtagtta ttattttgtc gttaggaatt gcaggacctt
    21121 tacttgaaac gatgaatttt gttgatggtc ttgcaaagat aggaactatt gcaaattcta
    21181 ttaattcaat tttagaagga aaagagcaaa ttcattccaa tgttgatgtg aaaataaaca
    21241 aatatgatat tgctctgcaa gatgtgaagt ttggatatga agaaggaaag gaaattcttc
    21301 atggagtgtc gttaaacata gaagaaggga caacgatagc ttttgttgga ccgagcggta
    21361 gtggaaagtc aactttggca aaactgatag caggatattg ggacataaat acaggaagca
    21421 taaaaattgg tggatataat ctccaagaga ttcctcttaa acagttatat agcttagtag
    21481 catttgtttc tcaagacaat ttccttttta atgaaagcat tagggaaaac atacgaatgg
    21541 gaaatccaag tgcaagtgat aaagaagttg aaaatattgc aaagaagtca ggctgccatg
    21601 attttattat gaatatggaa aaaggctatg acacagttgt cggaagcagt ggtagccata
    21661 tttccggagg agaaagacaa agaatctcaa tagcaagagc aatgcttaaa aaatccccga
    21721 tagtgatatt ggatgaagca acttcatata ttgatccgga gaatgaggtg attatcaaag
    21781 aagctctatc aaaattgata caaaataaaa ctgttatcgt tattgcacac aggttatcaa
    21841 caataacaga tgttcaacaa atcttttttg ttgagaatgg agagcttatt tcacatggta
    21901 aacataacga gttaatggaa gattgtgagc tatataaaaa aatgtggaat gctcatattg
    21961 gagtaaagga tggtgaaata aaatgctaag tgctttaaaa aaaattttag atttctcagg
    22021 tgatgagaag aaaaatatat accattctat atgggtaagt ttcttgtttg caatttttca
    22081 catgcttcaa atcagtgcaa tttattttat agttaaagct gtttctgaaa aagatatgag
    22141 tatgacacct gcgtggattg ctttgatact tcttgttgta agcatagtag gcagaagtat
    22201 tgcaaattat tattcacagt tacaacaatg ccatgcaagc tattttatgg ttgcaaataa
    22261 aagaatttca ataggggaaa tgttcaaaaa aattcctatg ggatttttta atggaaacaa
    22321 tgggggagaa gtcgttggta tttctacaac cgttttagaa gatgtggaaa atacggctgc
    22381 gatggttatg gtaaatacct tgtcgggatt tataaatact ataatcttta ctttgatgat
    22441 tttaatattt gaatggagaa taggttttat tgtaactgtc ggaagtctat tatatttggt
    22501 tattttgtca aaaatggaaa agaagtcaag agaggttctt cctaaacgac aaatggcttc
    22561 agcaaaatta gtagatactg ttttagaaca gattggagga atgtctgtta taaaatcctt
    22621 taatttaacc ggtaaaggtg atgagaaagt tagaggtgct attgaaaata ccagaaaaac
    22681 aaatcttgat tgtgaaaagt tgtttacacc ttacacgatt gttcaaaata ttcttttaga
    22741 tttgttcagc attttaatca taggtgcagg tatttt
//
LOCUS       DAVHSL010000128        17537 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254704-rid19266823.guided.047, whole
            genome shotgun sequence.
ACCESSION   DAVHSL010000128 DAVHSL010000000
VERSION     DAVHSL010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254704
            Sequence Read Archive: SRR2912548
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866613.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866613.1
            Genome Coverage       :: 210x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:30:40
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,248
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,043
            CDSs (with protein)               :: 2,043
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 72 of 159
            Pseudo Genes (incomplete)         :: 75 of 159
            Pseudo Genes (internal stop)      :: 51 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254704-rid19266823.guided.047"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="Pleural fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-04-27"
                     /collected_by="Catrin Moore"
     gene            307..735
                     /locus_tag="VVR39_002231"
     CDS             307..735
                     /locus_tag="VVR39_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6031598.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            814..1401
                     /locus_tag="VVR39_002232"
     CDS             814..1401
                     /locus_tag="VVR39_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU6031599.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYFLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            1683..1935
                     /locus_tag="VVR39_002233"
                     /pseudo
     CDS             1683..1935
                     /locus_tag="VVR39_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            2111..2364
                     /locus_tag="VVR39_002234"
                     /pseudo
     CDS             2111..2364
                     /locus_tag="VVR39_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2492..3721
                     /locus_tag="VVR39_002235"
     CDS             2492..3721
                     /locus_tag="VVR39_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6031600.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3741..6437
                     /gene="ppc"
                     /locus_tag="VVR39_002236"
     CDS             3741..6437
                     /gene="ppc"
                     /locus_tag="VVR39_002236"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU6031601.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6520..6737
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6850..7854
                     /locus_tag="VVR39_002237"
     CDS             6850..7854
                     /locus_tag="VVR39_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6031602.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7923..8789
                     /locus_tag="VVR39_002238"
     CDS             7923..8789
                     /locus_tag="VVR39_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6031603.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8786..9544
                     /locus_tag="VVR39_002239"
     CDS             8786..9544
                     /locus_tag="VVR39_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6031604.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9634..11394
                     /gene="dnaG"
                     /locus_tag="VVR39_002240"
     CDS             9634..11394
                     /gene="dnaG"
                     /locus_tag="VVR39_002240"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6031605.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPSE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDDNQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            11397..12506
                     /gene="rpoD"
                     /locus_tag="VVR39_002241"
     CDS             11397..12506
                     /gene="rpoD"
                     /locus_tag="VVR39_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU6031606.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12520..12849
                     /locus_tag="VVR39_002242"
     CDS             12520..12849
                     /locus_tag="VVR39_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6031607.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12964..14007
                     /gene="cpoA"
                     /locus_tag="VVR39_002243"
     CDS             12964..14007
                     /gene="cpoA"
                     /locus_tag="VVR39_002243"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU6031608.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            14023..15348
                     /locus_tag="VVR39_002244"
     CDS             14023..15348
                     /locus_tag="VVR39_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6031609.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            15379..15555
                     /locus_tag="VVR39_002245"
     CDS             15379..15555
                     /locus_tag="VVR39_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6031610.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15614..15748
                     /locus_tag="VVR39_002246"
     CDS             15614..15748
                     /locus_tag="VVR39_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU6031611.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15812..17122
                     /gene="obgE"
                     /locus_tag="VVR39_002247"
     CDS             15812..17122
                     /gene="obgE"
                     /locus_tag="VVR39_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU6031612.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            17132..17290
                     /locus_tag="VVR39_002248"
     CDS             17132..17290
                     /locus_tag="VVR39_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6031613.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         5481 a         2986 c         3901 g         5169 t
ORIGIN      
        1 atacacacaa ggaaatcatc gccaaactgg actacgacgc accatgttga ggcagtatca
       61 ctgcttgtac aagctgaggc atcagcgaag tagaagtaaa tgatctccca tacgatagga
      121 ctcgtagaat gaggagggaa accgacgaaa tgataaggta agtccgaacc gctgagtgcg
      181 tggctctgct cttccgatct gagacagtcg aaaagtagaa ggggatggta ttggtatcaa
      241 tcaatgagta acaaagtatc agcatgattc gaaacattta cttgtaattt gcggaggaac
      301 atcaatatgg atggaataac aaaagatttt ataaaaacgg ctaaactaat gaaacaatta
      361 tggccccaat tgaccgataa agaagctatt gatgaagtaa aaaaatatac gaatggcaaa
      421 aatactgcaa tctttactga agttgaaggt gacacaattg taggtctagc actatgttca
      481 ctcagatttg attatgttga aggttgtaaa tatagtcctg ttggattctt agaagggatt
      541 attgttgacg aggaatatcg tttaaaggat attgctaaaa atctctgtac aaaatgtgag
      601 gaatgggcga aaaataaagg atgtaaggaa tttgcaagtg actgtacttt aacgaatacg
      661 gattctataa gatttcatct caatattgga tttcaggagg caaatagaat tattcatttt
      721 aagaaaaaat tataatttag aaacgtgaat aaacttgttt aaactttatg tatctttaga
      781 aagtgtgtta acttgaaaga acaaattttt ttgatgggtg ggaatccccc aatgaagaaa
      841 tatagtattg ttgataaaat tgtattatca accaagatta aaagaattat catttttaca
      901 gtttttcgag aaaattggga accgtacatg aaaaagtaca cggaagtttt tcaaagtcaa
      961 tttcctaatc taaacattga ttactttctc ctggacactg agcagattga tcttgatagc
     1021 tatctagatg ctgacataat tatcatcggt ggtggaaata cggaaaaata tattgctact
     1081 tatgttaatc aggagttcaa aagttatatc gatcatatgc ttaataaaga ggcaaaaatt
     1141 ataggatttt ctgcaggagc cctactatta ggagaaaaag tctatgtctc acctaatgat
     1201 aattcagatc atcagataaa gataaaaaat ggattaggac tctttagtca gtttttaatt
     1261 agtgtccatt atgattcctg gaatgataaa gcaaataagg atagagctga agaactcgtt
     1321 aatgttccca taattccact aaatgatcat tcttgtcttg tattggataa acttggaaac
     1381 atcatagaga aaattgacta actttcataa tgtaaaaatg gatctaggaa ataaaagtgt
     1441 agacgaactg gataggttac tagtgaaaac tgcaaaaagt gttgtaaagt gaatcggagt
     1501 gtgcttgatg gattttagta gtaagatagc cataaataaa ggctggtcag atgataaaaa
     1561 atattgtgtg acagatcaaa atcagtaaaa atatttcttg cgtgtttctg ataagtcgaa
     1621 gttagattat aaaaaaattt gaatttgata tgatggagaa agtagcttct cttggagttc
     1681 cgatgtgtaa accaattagc attgaactct gcgatgacga agtacattct ttacacgaat
     1741 ggatggatag acggaagaga tgcaatagat agcattttaa cttattcaga aaaccaacaa
     1801 tacacatatg gtgtagaagc aggaaagata cttagaaaga ttcatacaat tcctgctaca
     1861 gaagtttgtg aagattggga aatctttttt aatctaaaaa ttgatgataa aatctccaac
     1921 gaaatgatat ggtaagtccg aaacgctcag tgtgtaagct tgttgctaaa agcgtaaaaa
     1981 ccttggaacg aaaggaataa tagacttcct gcgaaacaaa aatacaatac aataaaacta
     2041 tggatgatga agcaagtaaa caattaagcg atagccgttt caagagcctt gtaggtgttc
     2101 agcgcacgag atgttagctg tgttaaaaac agcttatcaa cgcaacgtaa acgcgcaaaa
     2161 ggtggacgaa aaaccaaatt aagcctagac gatctcctca tggtaactat tcaatacatg
     2221 cgagaatagc ccacttatga acaaattgcg gctgattttg gcattcacga aagcaacata
     2281 attagtcgga gccaatgggt tgaagtaact cttgttcaaa atggttttac gatttcaaat
     2341 tctgccctaa ttatgaaaaa cagtaaaatt cgaaggattg taaggtaaga gtttttttct
     2401 ttctgaaaaa atggtataat agcaatcaaa actagaaaat aaaacggaat ttggaacaga
     2461 tttgtctgta tcctagtaga gtggtgatac tatgaagatt agtaagaggc acttattaaa
     2521 ttattccatc ttgattccct acttgctttt atctattttg ggcttgattg tggtctattc
     2581 gaccaccagt gctattttaa ttgaagaagg caagagcgcc ttgcagttgg ttcgaaacca
     2641 aggaatcttt tggattgtta gtttgatact gattgcctta atttataaat tgagactaga
     2701 ttttttgaga aatgagcgac taatcatttt agttatatta atagaaatgc ttttattgtt
     2761 cttggctcgt tttattggta tttccgtaaa cggggcatac ggttggattt cggttgcagg
     2821 agtaactatt cagccagctg agtacttaaa aatcattatt atttggtatt tagctcaccg
     2881 attctccaaa cagcaagaag aaatagctac ttatgatttt caagttttga ctcaaaatca
     2941 atggcttccc cgtgctttta atgattggcg attcgttctc ctagttctga ttggaagttt
     3001 gggaattttc cctgatttag gaaatgcgac tattttagtc ttggtttcct tgattatgta
     3061 tacagttagt ggaatcgctt atcgctggtt ttcaaccatt ctggcgctcg tatctgccac
     3121 ttctgtcttt gtcttgacca ctatcagcct aatcggtgtt gagacctttt caaaaattcc
     3181 agtatttggc tatgtagcca agcgctttag tgcctttttt aatccttttg ccgatcgtgc
     3241 tgatgcaggt caccagttag ctaattctta ttttgccatg gtcaatggtg gttggtttgg
     3301 tctaggtctt ggaaactcga ttgaaaaacg aggttatttg ccagaagctc atacagactt
     3361 tgtcttttct atcgtgattg aagaatttgg ctttgttggt gccagtctta ttttagctct
     3421 cttgtttttc atgattttgc ggattatctt ggtcggtatc cgagcggaga atcctttcaa
     3481 tgccatggtt gcactcggtg tcggagggat gatgttggtt caggtatttg tcaatatcgg
     3541 agggatttcg ggcttgattc catctacagg agtgactttc cctttcttat cccagggtgg
     3601 aaatagtctt ctagtcttat cagtggcagt agcctttgtc ttaaatattg atgccagtga
     3661 aaaacgcgct aagttgtacc gagaattgga aaatcaacca atgaaccttc tgttgaagta
     3721 ggataaagaa aggatagttt atgtctcttc aaaaattaga aaattatagt aataaaagtg
     3781 ttgtgcaaga agaagtcttg attctaacag aattactgga agatattact aaaaatatgc
     3841 ttgccccaga gacctttgaa aaaataatac agttgaaaga attatcaacg caggaagatt
     3901 atcaaggtct aaaccgtcta gtgactagct tatcaaatga tgaaatggtc tatatttcac
     3961 gctatttctc tatcttacct cttttgatta atatttcaga ggatgtggat ttagcttatg
     4021 aaatcaatca tcaaaataat attgatcagg actatttagg taaattatct acaacgatta
     4081 aattggtagc agaaaaggaa aatgccgttg agatcctaga acacttgaat gttgtccctg
     4141 ttttgacagc ccatccaaca caagtgcaac gcaaaagtat gttggattta acaaatcata
     4201 ttcatagtct tttgcgtaaa taccgtgatg ttaagttggg gttgatcaat aaagataaat
     4261 ggtacaatga tttgcgtcgt tacatcgaaa ttatcatgca gacagacatg attcgtgaga
     4321 aaaaattaaa agtgactaac gaaatcacga atgctatgga atattataac agctcctttt
     4381 tgaaagctgt acctcatttg acgacggagt ataagcgctt agcgcaagcg catggtctga
     4441 atttaaaaca ggctaaacca atcaccatgg gtatgtggat aggtggtgac cgtgatggaa
     4501 atccatttgt tacagcagag accttgaagc agtctgcact cactcaatgt gaagtcatca
     4561 tgaactatta tgataaaaag atttaccaac tttatcgtga attttctctt tcaactagca
     4621 ttgtcaacgt cagcaagcaa gtcagagaaa tggctcgtca atccaaggat aactcgattt
     4681 accgcgaaaa agagctttac cgtcgtgcct tgtttgatat tcaatcaaaa attcaggcaa
     4741 ctaaaaccta tctgattgag gatgaagaag ttgggactcg ttatgaaacc gccaatgatt
     4801 tctacaagga tttgattgcc attcgagatt ctctactaga aaataagggc gagtccttga
     4861 tttcaggtga ttttgtggaa ttattgcagg cagtagagat atttggtttt tacctagcat
     4921 caattgatat gcgacaagac tctagcgtct atgaagcctg tgtggcagaa ctcttgaaat
     4981 cagcaggaat tcattctcgt tatagcgagt tgagcgaaga agaaaagtgt gaccttctct
     5041 tgaaagaatt agaagaagat ccccgaattc tttctgcgac tcacgcagaa aaatcagaat
     5101 tattagcaaa agaactagct atttttaaga cggctcgtgt tttgaaagat aagttgggag
     5161 atgatgtcat ccgtcagacc atcatttcac atgcaaccag cctttctgat atgctagaat
     5221 tagctattct gttaaaagaa gtaggactgg tggatacgga aagggcgcgt gttcagattg
     5281 ttcccctttt tgaaacaatt gaagacttgg atcattcaga ggaaacaatg agaaaatatc
     5341 tttctcttag ccttgccaaa aaatggattg actcacgaaa taactaccaa gaaatcatgc
     5401 ttggctactc tgacagtaat aaagatggcg gttacttgtc atcatgttgg accctctaca
     5461 aggctcaaca acaattgact gctattggag atgaatttgg cgttaaggtt accttcttcc
     5521 atggtcgtgg tggtactgtc ggtcgtggtg gtgggccaac ctatgaagcc attacatctc
     5581 aaccgctcaa gtctatcaag gatcgtatcc gcttgacgga gcagggtgaa gtaattggga
     5641 ataaatacgg taacaaagac gccgcttact ataaccttga aatgctagta tcggcagcta
     5701 ttaaccgtat gattactcag aagaagagcg ataccaatac cccaaatcgt tatgaagcca
     5761 ttatggatca agtagtggac cgtagttacg acgtctaccg tgatttggtc tttggtaatg
     5821 agcatttcta tgattatttc ttcgagtcaa gtccaatcaa ggctatttca agttttaata
     5881 ttggttctcg tccagccgct cgtaagacta ttactgaaat cggtggattg cgtgccatcc
     5941 cttgggtatt ctcatggtca cagagtcgtg ttatgttccc tggatggtac ggggttggtt
     6001 caagcttcaa ggaatttatc aataaaaatc cagagaatat tgctatctta cgagatatgt
     6061 accaaaattg gcctttcttc caatcgcttc tttcaaatgt tgatatggtt ttgtcaaaat
     6121 caaatatgaa tattgctttt gaatatgcta aactttgtga agacgagcaa gttaaggcca
     6181 tctatgagac tattttaaat gaatggcaag ttactaagaa cgttatcttg gctattgaag
     6241 gacatgacga actcttagct gacaatccat atctaaaagc tagtctggat taccgtatgc
     6301 cttactttaa tattctcaac tatattcagt tggagttgat taaacgccaa cgtcgtggag
     6361 aattgtctag tgatcaagaa cgattgattc atatcaccat caacggaatt gcgacaggat
     6421 tgcgtaattc aggttgataa ttttcaagag tgaatgctaa aagtgaatat caaaaaaatt
     6481 ctaatagact attgacaagt agtttaaaaa tgatataatt taaccattca gaaaagtaat
     6541 catacaaact ttttagagag tctgtggtag ctgaaaacag ataagtggcg atgatgaaaa
     6601 ttgggctgaa tgctatttag aatttgaaat tataaaaatt cggtaagcac accttacagt
     6661 gcatctcgtt attgcgagac tgagcgatag ggaaattccc tataattgag gtggtaccgc
     6721 gcatcgacgt cctcacacaa gttttttgtg tgaggatttt tttgatggag gttagtatgg
     6781 aaagaaaacg atggcgtcgc ttgtttagat aagtgaaata tgttaaagga aataaaaagg
     6841 agaaacagaa tgaaaaataa acgtttaatt ggaattattg ctgcattagc agtcttagta
     6901 gcaggaagct tgatttattc ttcaatgaat aaatcagaag ctcagaataa taaggatgag
     6961 aagaaaataa ctaagattgg tgtgcttcaa tttgtgagcc atccatccct tgatttgatt
     7021 tataaaggga tccaagatgg acttgcagaa gaaggatata aagatgatca agttaaaatt
     7081 gattttatga actcagaagg tgaccaaagt aaggttgcga caatgagtaa acaattggtt
     7141 gcaaatggga atgaccttgt ggttggtatc gcaacaccag cagcccaagg gttggctagt
     7201 gcaacaaaag acctaccggt tatcatggcc gctattacag acccaattgg tgctaacttg
     7261 gttaaagatt tgaaaaaacc aggtggcaac attacagggg tatctgacca caatccagct
     7321 caacaacaag ttgaactcat caaggctctg acaccgaatg tgaaaacaat cggagctctt
     7381 tactcaagta gcgaagacaa ttcaaaaaca caggtcgaag aatttaaggc ttatgctgaa
     7441 aaagcaggtc tgacagtgga aacatttgca gttccttcaa caaatgaaat tgcctcaact
     7501 gtcactgtta tgactagcaa ggtagatgct atttgggttc caattgataa caccattgca
     7561 tcaggatttc caacggttgt ctctagcaat caaagttcta agaaaccaat ttatcccagt
     7621 gcgacagcta tggtagaagt aggtggtttg gcatcagttg taattgacca acatgacctt
     7681 ggtgtggcaa caggtaaaat gattgtgcaa gtcttgaaag gtgcaaaacc agccgatacc
     7741 ccagtcaatg tcttttcaac tggtaagtca gtcatcaata aaaaaatagc acaagaacta
     7801 ggtattacta ttcctgagtc tgttctcaaa gaagcaggac aagtcatcga ataaataagg
     7861 tagggaggag gagactcttc ccatttttta aaaagatgaa tatagaaagg attaaataaa
     7921 atatgattgt ttccattatt tctcaaggat ttgtctgggc tattctaggt ctgggaatct
     7981 ttatgacatt taggatttta aactttccag atatgacgac agaaggttcc ttccctcttg
     8041 ggggagctgt tgctgtcact ttgataacca aaggcgtgaa cccattttta gcgacacttg
     8101 ttgctgtagg ggcaggttgt ttggctggaa tggcagcagg ccttctttat acaaaaggga
     8161 agatcccaac cttgctctca gggattttgg tgatgacttc ttgtcactca atcatgctct
     8221 tgattatggg acgtgcgaat ttaggcctgc ttggaaccaa gcaaattcag gatgttttgc
     8281 cttttgattc ggatttgaat caactcttga caggtctcat ctttgtgagt attgttattg
     8341 ctctcatgct ctttttcttg gacactaaac tcggacaagc ctatattgct acaggggata
     8401 atcctgatat ggctagaagt ttcgggattc atactggacg catggagctc atgggcttgg
     8461 tcttatcaaa tggtgtgatt gcccttgcag gtgccctcat tgctcagcaa gaaggttatg
     8521 ccgatgtgtc tcgagggatc ggggttatcg ttgtggggct tgcaagtttg attattggag
     8581 aagttatttt caagagtttg agcttggcag agcgtttggt tactatcgtt gtaggttcta
     8641 tcgcttatca atttttagtg tgggcagtta tcgcacttgg ctttaataca agttaccttc
     8701 gtttatacag tgccttgatt ttagcagtct gcctcatgat tccaacattt aagcaaacaa
     8761 tcttgaaagg agccaagtta agcaaatgac agcaattgta gaattaaaaa atgcaaccaa
     8821 aatcgttaaa aatggctttg atgaagaaaa gattatttta aatgatgttt ccttagaaat
     8881 ttttgaacgg gactttatca cgattttggg cggaaatggt gctggaaaat caaccctctt
     8941 taacactata gcagggacct tatcactaac tagtggaact atccgtattt taggtgaaga
     9001 tctcactaag ttttcacccg agaagcgtgc caagtacctg tctcgtgtct tccaagatcc
     9061 aaagatgggg acagctcccc gtatgacggt cgctgaaaat cttttaatcg ccaagtttcg
     9121 tggtgaaaag cgtggattgt taccacgacg cttgactagc tataaggatg aatttcaggt
     9181 aaccattgaa aaagtaggaa atggtcttga gaaacacttg aatacaccga ttgagttctt
     9241 atcaggtgga caaagacagg ctttgagtct cttgatggca accttgaagc gacctgaatt
     9301 actcctgtta gatgagcata ctgctgccct ggatccaaag actagtgttg ctttgatgga
     9361 attgacagat gaatttgtta agaaagatca gctaacagcc cttatgatta ctcatcatat
     9421 ggaagatgct ctcaaatacg gcaatcgctt gattgtcatg aaagaaggac ggattatcca
     9481 agatttaaac caagaagaaa aagcaaaaat gaaaatctct gattattatc aactctttga
     9541 ataaagtagg gaaaatgagt gaaatggttt actttttttc tgaaataaag tatactatat
     9601 aaagtaaact atgataacat ggaggtattg tgtatggttg acaaacaagt cattgaagaa
     9661 atcaaaaaca atgccaacat tgtggaagtc ataggagatg tgatttcttt acaaaaggca
     9721 ggacggaact atctagggct ctgtcctttt catggtgaaa aaacaccttc tttcaacgtt
     9781 gtagaggaca agcagtttta ccactgtttt ggttgtggtc gctcaggtga tgtctttaaa
     9841 ttcatcgagg agtaccaagg ggttcccttt atggaggctg tccaaatctt aggtcagcgt
     9901 gtcgggattg aggttgaaaa accgctttat agtgaacaga agccagcctc gccttaccaa
     9961 gatctttatg atatgcacga agatgcggct aaattttacc atgctattct catgacaacg
    10021 actatgggcg aagaggccag aaattacctt tatcagcggg gtttgacaga tgaagtgctt
    10081 aaacattttt ggattggttt agcaccttca gaacgaaact atctctatca acgtttgtct
    10141 gatcagtatc gtgaagagga tttactggat tcaggcctgt tttatctctc ggatgacaat
    10201 caatttgtag acacctttca caatcgcatt atgtttcccc tgacaaatga ccaaggaaag
    10261 gtcattgcct tctcaggtcg tatctggcaa aaaacggatt cacaaacttc taagtataaa
    10321 aacagccgat cgactgcaat ttttaacaaa agttacgaat tatatcatat ggatagggca
    10381 aaaaaatctt ctggaaaaac tagtgagatt tacctgatgg aaggattcat ggatgttatt
    10441 gcagcctatc gggctggaat cgaaaatgct gtggcgtcga tgggaacggc cttgagtcga
    10501 gagcatgttg agcatctgaa aaggttaacc aagaaattgg ttcttgttta cgatggagat
    10561 aaggctgggc aagccgcgat attgaaagca ttggatgaaa ttggtgatat gcctgtgcaa
    10621 atcgttagta tgcctgataa cttggatcct gatgagtatc tacaaaaaaa tggtccagaa
    10681 gacttggcct atctattaac aaaaactcgt attagtccga ttgagttcta cattcatcag
    10741 tacaaacctg aaaacagtga aaatctgcag gctcagattg agtttattga aaaaatagct
    10801 cccttgattg ttcaagaaaa gtccatcgct gctcaaaaca gctatattca tattttagct
    10861 gacagtctgg cgtcctttga ttatacccag attgagcaga ttgttaatga gagtcgtcag
    10921 gtgcaaaggc agaatcgcat ggaaagaatt tccagaccga cgccaatcac catgcctgtc
    10981 accaagcagt tatcggctat tatgagggca gaagcccatc tactctatcg gatgatggaa
    11041 tcccctcttg ttttgaacga ttaccgtttg cgagaagact ttgcatttgc tacacctgaa
    11101 tttcaggtct tatatgactt gcttggccag tatggaaatc ttcctccaga agttttagca
    11161 gagcagacag aggaagttga aagagcttgg taccaagttt tagctcagga tttgcctgct
    11221 gagatatcgc cgcaggaact tagtgaagta gagatgactc gaaacaaggc tctcttgaat
    11281 caggacaata tgagaatcaa aaagaaggtg caggaagcta gccatgtagg agatacagat
    11341 acagccctag aagaattgga acgtttaatt tcccaaaaga gaagaatgga gtaataatgg
    11401 caacaaaaca aaaagaagta acaacatttg acgtacaggt agcagaattt atccgtaatc
    11461 ataagcaaaa agggacagca acagatgatg aaatcaatgc aagtctggtt attcctttta
    11521 ccttggacgc tgatgggatt gaagatctct tgcaacggat tcaggatgca ggcatttcta
    11581 tcacagataa cgaaggaaat ccaagtgcgc gtgttcttag caatgaagaa gaaccagaac
    11641 tcagcgatga ggacttgatt gggtcaactt ctgctaaggt caatgaccct gtccgtatgt
    11701 acttgaaaga aataggggtc gttcctctct tgaccaatga agaggagaaa gagttggcac
    11761 tggctgttga agctggtgat atcgaagcca aacaacgtct tgcggaagcc aatcttcgtt
    11821 tggttgtttc cattgccaaa cgctatgtcg gtcgtggcat gcagttcctt gacttgattc
    11881 aagaaggaaa tatgggcttg atgaaggcgg ttgacaagtt tgactattct aaagggttca
    11941 agttttcaac ttatgcaact tggtggattc gtcaggctat cactcgtgct attgcggacc
    12001 aagctcgtac catccgtatc ccagttcaca tggttgaaac tatcaataaa ttggttcgtg
    12061 aacagcggaa tctccttcaa gaattggggc aagatccgac accagaacag attgctgaac
    12121 gaatggatat gacacctgat aaggttcgtg aaatcttgaa gattgcccaa gaaccagtat
    12181 ctcttgaaac tcctatcggt gaagaggacg atagccacct tggagacttt atcgaagatg
    12241 aagtgattga aaatccagtg gattatacga ctcgtatcgt cttgcgtgag caattggatg
    12301 aaatcttaga tactcttaca gaccgtgaag aaaatgttct gcgtctacgt tttggactag
    12361 atgatggaaa aatgcgcaca cttgaagatg tggggaaagt ctttaacgta actcgtgagc
    12421 gtatccgtca gattgaagca aaggctttga gaaaactacg ccaaccaagt cgtagcaaac
    12481 cgcttcgtga ttttattgaa gactaagagt gaggaaaata tggcttatac agaagagcaa
    12541 attgaaaaca tcaaaacacg gattttaaca gccttggaag aagtcatcga ccctgagttg
    12601 ggaatcgata ttgtcaatct tggtttgatc tatgagattc gttttgacgg tgacacaggg
    12661 caaacagaga ttgacatgac tttgacaact atgggttgtc ccttagcaga ccttttgaca
    12721 gaccagattt atgatgctat gatagaggtt ccagaagtaa cggatactga ggttaaatta
    12781 gtctggtatc cagcctggac agttgaaaaa atgagtcgct atgcccgcat tgccctaggc
    12841 attaagtaaa catataaaag catgtgagag actgttggaa aagcgaggaa atttcccctc
    12901 ttttcctcta gtctctcctt tcttttgctg attttattca aagaaaatga tataatagta
    12961 gttatggaga aaaagaaatt acgcatcaat atgttgagtt caagtgagaa agtagcagga
    13021 cagggagttt caggtgctta ccgtgaatta gttcgtcttc ttcaccgtgc tgccaaggac
    13081 caattgattg ttacagaaaa tcttccaatc gaggcagatg tgactcactt tcatacgatt
    13141 gattttccct attatttatc aaccttccaa aagaaacgct cagggagaaa gattggctat
    13201 gtgcatttct tgccagctac acttgaggga agtttgaaaa ttccattttt cttaaaggga
    13261 attgtgaaac gctatgtatt ttctttttac aaccggatgg agcacttggt tgtggtcaat
    13321 cctatgttta ttgaggattt ggtagcagct ggtattccac gtgaaaaagt gacctatatt
    13381 cctaactttg tcaacaagga aaaatggcat cctctaccac aagaagaggt agtcagactg
    13441 cgcacagatc ttggtcttag tgacaatcag tttatcgtag taggtgctgg gcaagttcag
    13501 aaacgtaaag ggattgatga ctttatccgt ctggctgagg aattgcctca gattaccttt
    13561 atctgggctg gtggcttctc ttttggtggt atgacagatg gttatgaaca ctataagaaa
    13621 attatggaaa atccccctaa aaatttgatt tttccaggca ttgtatcgcc agagcggatg
    13681 cgcgaattgt atgctctagc ggatcttttc ttgttgccta gttacaatga gctctttcct
    13741 atgactattt tagaagctgc gagttgtgag gctcctatta tgttgcgtga tttagatctc
    13801 tataaggtga ttttggaggg aaattatcgg gcgacagcgg gtagagaaga gatgaaagag
    13861 gctattttgg aatatcaagc aaatcctgct gccttaaaag atctcaaaga aaaggctaag
    13921 aatatttcca gagagtattc tgaagagcat ctgttacaaa tctggttgga cttttatgag
    13981 aaacaagccg ctttagggag aaagtaaaaa gtgaggtaat ctatgcgaat tggtttattt
    14041 acagatacct attttcctca agtttctggt gttgcgacca gtattcgaac cttgaaaaca
    14101 gaacttgaaa agcagggaca tgctgttttt atctttacga cgacagataa ggatgtcaat
    14161 cgctacgaag attggcaaat tatccgcatt ccaagtgttc ctttctttgc ttttaaggat
    14221 cgtcgctttg cctaccgagg ttttagcaag gcacttgaaa ttgctaaaca gtatcagcta
    14281 gatattatcc atactcagac agaattttct cttggcctgt tggggatttg gattgcgcgt
    14341 gaattgaaaa ttccagtcat ccatacctat cacacccagt atgaagacta tgtccattat
    14401 attgctaagg ggatgttgat ccggccgagt atggtcaagt atctggttag aggtttcctg
    14461 catgatgtgg atggggttat ttgtcctagt gagattgtcc gtgacttgct atctgattat
    14521 aaggtcaagg ttgaaaaacg ggtcattcct actgggattg aattagccaa gtttgagcgt
    14581 ccggaaatca agcaggaaaa tttgaaagaa ctgcgtagta aactagggat tcaagatggt
    14641 gaaaagacgt tgcttagtct ttcgagaatc tcctatgaaa aaaatattca agcagtttta
    14701 gcagcctttg ctgatgttct gaaagaggaa gacaaggtta aactggtagt agctggggat
    14761 ggcccttatc tgaatgacct caaagagcaa gcccagaacc tagagattca agactcagtc
    14821 atctttacag ggatgattgc tcctagtgag acggctcttt actataaagc ggcggatttc
    14881 ttcatttcgg catcgacaag cgaaacgcaa ggtttgacct acttggaaag cttagccagt
    14941 ggaacacctg tcattgctca cggaaatcct tatttgaaca acctcatcag tgataaaatg
    15001 tttggaacct tgtactatgg agaacatgat ttggctggtg ctattttgga agccctgatt
    15061 gcaacaccag acatgaacga gcatacctta tcagagaaat tgtatgagat ttcagctgag
    15121 aactttggga aacgagtgca tgagttttat ctggatgcca ttatttcaaa taacttccag
    15181 aaagatttgg ctaaagatga tacggtcagt cagcgtatct ttaagacagt tttgtatctt
    15241 cagcaacagg tggttgctgt acctgtaaaa ggatctagac gcatgttgaa ggcttcaaaa
    15301 acacagttga tcagtatgag agactattgg aaagaccatg aagaatagaa agaggaacag
    15361 ctatgaaaaa aacaattaat gagaagcggt cgtgataaaa agattgcggg tgtttgtgct
    15421 ggggtggccc attatctgga tatggatccg actatcgttc aagtcatttg gggtgttctt
    15481 acttgctgtt acggagctgg aattgtagct tacattattt tatggattat cgcaccagta
    15541 gcaactgact attgaaaact agctcaattc atgctaagat aatagaaaat agaatgtaac
    15601 gaaggagaga aaaatggcat ttggagataa tggaaatcgt aaaaaaacta tgtttgagaa
    15661 aataaccttg tttatcgtga ttatcatgct agtagcaagt ttattgggaa tttttgcaac
    15721 tgcaattggt gccctcagta atctataaaa tagattcaag aaaatttagt gactgggatt
    15781 tcccagccct tttttaaagt gagaagaaat aatgagtatg tttttagata cagctaagat
    15841 taaggtcaag gctggtaatg gtggcgatgg tatggttgcc tttcgtcgtg aaaaatatgt
    15901 ccctaatgga ggcccttggg gtggtgatgg tggtcgtgga ggcaatgtgg tcttcgttgt
    15961 agacgaagga ctacgtacct tgatggattt ccgctacaat cgtcatttca aggctgattc
    16021 tggtgaaaaa gggatgacca aagggatgca tggtcgtggt gctgaggacc ttagagttcg
    16081 agtaccacaa ggtacgactg ttcgtgatgc ggagactggc aaggttttaa cagatttgat
    16141 tgaacatggg caagaattta tcgttgccca cggtggtcgt ggtggacgtg gaaatattcg
    16201 tttcgcgaca ccaaaaaatc ctgcaccgga aatctctgaa aatggagaac caggtcagga
    16261 acgtgagtta caattggaac taaaaatctt ggcagatgtc ggtttagtag gattcccatc
    16321 tgtagggaag tcaacacttt taagtgttat tacctcagct aagcctaaaa ttggtgccta
    16381 ccactttacc actattgtac caaatttagg tatggttcgc acccaatcag gtgaatcctt
    16441 tgcagtagcc gacttgccag gtttgattga aggggctagt caaggtgttg gtttgggaac
    16501 tcagttcctc cgtcacatcg agcgtacacg tgttatcctt cacatcattg atatgtcagc
    16561 tagcgaaggc cgtgatccat atgaggatta cctagctatc aataaagagc tggagtctta
    16621 caatcttcgc ctcatggagc gtccacagat tattgtagct aataagatgg acatgcctga
    16681 gagtcaggaa aatcttgaag aatttaagaa aaaattggct gaaaattatg atgaatttga
    16741 agagttacca gctatcttcc caatttctgg attgaccaag caaggtctgg caacactttt
    16801 agatgctaca gctgaattgt tagataagac accagaattt ttgctctacg acgagtccga
    16861 tatggaagaa gaagcttact atggatttga cgaagaagaa aaagcctttg aaattagtcg
    16921 tgatgacgat gcgacatggg tactttctgg tgaaaaactc atgaaactct ttaatatgac
    16981 caactttgat cgtgatgaat ctgtcatgaa atttgcccgt cagcttcgtg gtatgggggt
    17041 tgatgaagcc cttcgtgcgc gtggagctaa agatggggat ttggtccgca ttggtaaatt
    17101 tgagtttgaa tttgtagact aggagactgg tatgggagat aaaccgatat ctttccgaga
    17161 tgcggatggt aattttgttt ccgccgcaga cgtttggaat gaaaagaaat tggaagaact
    17221 atttaatcgt ctaaatccaa atcgtgcctt gagattggca cgaactaaaa aggaaaatcc
    17281 atctcagtaa agaagctaaa aaatcccgtg cctcatcaga cacgggattt tgtggtacga
    17341 cgggcatgta tagcgaactg aatctggaat agcacagcat atcttctaaa atattgttat
    17401 aaattgattt gaatttcaaa attaaattgt ttgattctta tttcaatttg ttatagtata
    17461 tctgatgtca aagttctcgg cgagtcaaat agcgattccc aagcctgact atcgtgaggt
    17521 agcggattaa aatggtc
//
